Pehea e hoʻohana ai i ka lāʻau lapaʻau Glyclazide? > He hoʻomaʻemaʻe a me ke pale aku

Ka puka ʻai - nā papa: papaʻa-cylindrical, aneane keʻokeʻo a ʻele paha paha, me ka pilikia a me ka bevel (10 kēlā me kēia i loko o ka pā kīwila, i loko o ka pahu kīwila 3 a i ʻole 6 mau pākaʻi a me nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana o Gliclazide).

ʻO ka ʻōmole o 1 papa:

mea waiwai: gliclazide - 80 mg,
Nā mea kōkua: kō kōpau 1500 (ʻāpana kūhā pregelatinized kākā), ʻoi sodium lauryl sulfate, lactose monohydrate, magnesium stearate, croscarmellose sodium.

Lapaʻau lāʻau

ʻO Glyclazide - kahi derphative sulfonylurea o ka lua o ka hanauna, kahi kuʻuna hypoglycemic.

ʻO ka kaila o ka hana o ka lāʻau lapaʻau ma muli o ka hiki ke hoʻoikaika i ka hoʻihoʻi ʻana i ka insulin pancreatic, hoʻonui i ka hopena o ka insulin-secretory o ka glucose, a hoʻonui i ka ʻike ʻana i nā kiko i ka insulin. Hoʻololi ka Gliclazide i ka hana o nā kinipopa intracellular e like me ka glycogen synthetase muscle. Hoʻololi i ka manawa manawa mai ka manawa o ka ʻai ʻana a i ka hoʻomaka ʻana i ka huna ʻana i ka insulin. ʻAʻole ia e like me nā derivatives sulfonylurea, e hoʻihoʻi hou i kahi wā kiʻekiʻe i ka neʻe ʻana o ka insulin. Hoʻemi i ka hyperglycemia postprandial.

ʻO ka maikaʻi ʻo Gliclazide i ka metabolic a me latent diabetes mellitus, ʻo ia hoʻi i nā mea maʻi me ka obesity kumukānāwai exogenously. ʻO ka normalization o ka paukū glycemic i ʻike ʻia i kekahi mau lā ma hope o ka hoʻomaka ʻana o ka mālama ʻana. Ke pale aku nei ka lāʻau lapaʻau i ka hoʻomohala ʻana o ka microvasculitis, me ka hōʻino ʻia i ka retina o ka maka. Kākoʻo i ka hoʻohui platelet. Hoʻonui i ka hana fibrinolytic a me ka heparin, a me ka hoʻomanawanuiʻo heparin. Hoʻonui koʻikoʻi i ka ʻikepili hakakā male. Hōʻike i ka hana antioxidant, hoʻomaikaʻi i ka vascularization.

Me ka nephropathy maʻi maʻi, ua hoʻemi ʻia ka proteinuria. Me ka hoʻohana lōʻihi, kōkua ia i ka hōʻemi i ka proteinuria i nā maʻi me ka nephropathy maʻi.

No ka mea he hopena nui ka lāʻau lapaʻau i ka wana o ka wana o ka huna ʻana i ka insulin a ʻaʻole ia e hoʻoulu i ka hyperinsulinemia, ʻaʻole ia e alakaʻi i ka hoʻonui ʻana i ke kaupaona kino. Eia kekahi, i nā maʻi maʻi momona, ua hāʻawi ka gliclazide i ka pohō kaumaha, e hōʻemi ana i ka ʻai haʻahaʻa.

Loaʻa ia i ka hana antiatherogenic, e hōʻemi i ka piʻiʻana o ka kolamu nui ma ka koko.

ʻO nā mea antioxidant a me nā hemovascular o gliclazide e kōkua i ka hōʻemi i ka hopena o ka hoʻomohalaʻana i nā hoʻopiʻi vascular i nā maʻi me ka maʻi mellitus.

Lapaʻau lāʻau

Hoʻohālikelike ʻia ka Gliclazide e ke kaʻe kiʻekiʻe. Ma hope o kahi kahena waha he 40 mg, ʻo ka nui loa o ke kaila (C_max) ua nānā ʻia ma hope o 2-3 mau hola a helu i 2-3 μg / ml, ma hope o ka lawe ʻana i ka nui o ka 80 mg, mau hōʻailona kēia he 4 mau hola a he 2.2-8 μg / ml, ma kēlā.

ʻO ka pilina me nā protein plasma he 85–97%, ka lōhele hoʻoili he 0.35 l / kg. Loaʻa ka kūlehuʻu kūloko i loko o 2 mau lā.

Hoʻomili ʻia ka Gliclazide i ke kōpaʻa me ka hoʻokumu ʻana o 8 mau metabolites. ʻO ka nui o ka metabolite koʻikoʻi he 2-3% o ka nui o ka nui i lawe ʻia, ʻaʻole ia o nā waiwai hypoglycemic, akā e hoʻopilikia ai ka microcirculation.

Ka hapalua ola (T_½) - mau hola 8-12. Ua hoʻokuʻu ʻia ka lāʻau lapaʻau nā mea nui e nā keiki: 70% - i ke ʻano o nā metabolites, ʻaʻole iʻoi aku ma mua o 1% - i loli ʻole. Ma kahi o 12% o gliclazide e hoʻopili ʻia e nā ʻōpū ma mua o nā metabolites.

ʻO nā hiʻohiʻona Pharmacokinetic i kekahi mau hihia:

hana ʻoi a me ka ate: i ka hihia o ka maʻi hepatic a me ka maikaʻi ʻole o ka hana ʻole, he loli i ka pharmacokinetics o gliclazide e hiki, hiki paha ke lōʻihi ka manawa o nā hypoglycemia i kēlā mau mea maʻi.
ʻoiau hele: ʻaʻole i nānā ʻia nā hiʻohiʻona pharmacokinetic.

Nā Hoʻohui

mellitus type 1 mellitus (me ka hoʻohana ʻana i ka mody mode MODE),
maʻi pākīpeka maʻi maʻi precoma and coma,
maʻi maʻamau ketoacidosis,
hyp- and hyperthyroidism,
pilikia hōʻeha a me / a i ʻole kaulū palupalu,
mau hoopoina a puhi
intolerance galactose, hemahema lactase, malabsorption glucose-galactose,
makahiki i 18 makahiki
hapai a lactation
con conidance con miconazole,
hypersensitivity i kekahi māhele o ka lāʻau lapaʻau, sulfonamides a i ʻole nā mea waiwai'ē aʻe o ka hui sulfonylurea.

ʻAʻole ia e hoʻohana i ka hoʻohana ʻana o Gliclazide i ka hui me danazol, phenylbutazone, ethanol.

ʻO Gliclazide, nā ʻōlelo e hoʻohana ai: ke ʻano a me ka helu ʻana

Pono e lawe ʻia i nā papa glyclazide me kaʻai me ka meaʻai.

I ka hoʻomakaʻana o ka pena, 80 mg (1 papa) maʻamau i kuhikuhi ʻia i ka manawa 1 i ka lā. I ka wā e hiki mai ana, koho ke kauka i ka ʻōmaʻomaʻo mālama, hiki iā ia ke 80-320 mg i kēlā me kēia lā. ʻAʻole pono kahi momona hoʻokahi ma mua o 160 mg. I ke kohoʻana i nāosa kiʻekiʻe, pono ʻoe e lawe i ka lāʻau lapaʻau 2 mau manawa i ka lā i ka wā nui.

ʻO ka papa hoʻomaka ʻana i nā maʻi maʻi (ma mua o 65 mau makahiki) he 40 mg (½ papa) i hoʻokahi lā. Inā pono, e hoʻonui hou ʻia ka pāpaʻi. Pono ka hana ʻana i nā ʻōpiopio ma waena o nā liʻiliʻi he 14 i lalo o ka kaohi o ke kahe koko o ka nui.

Ma ka hapa iki o kēlā me kēia lā (40-80 mg), ua ʻōlelo ʻia ʻo Gliclazide no ka poʻe maʻi me ka maʻi o ka maʻi / hepatic, a me nā maʻi maʻi, a me nā mea maʻi i ka hopena o ka ulu ʻana o ka hypoglycemia: ʻoi aku ka hoʻopiʻi a i ʻole ka uku endocrine (ʻo ka hypothyroidism, adrenal a me ka ʻōpū o ka pituitary). mau maʻi hōʻeha maʻi (me ka nui o ka maʻi puʻukui coronary nui, ka atherosclerosis nui, atherosclerosis koʻikoʻi o nā carotid arteri), ke kūpapa ʻole ʻole a hōʻino ʻole ʻia, ka wā ʻO ka hoʻopau ʻia ʻana o ka glucocorticosteroids ma hope o kā lākou alakaʻi lōʻihi ʻana a me / a i ʻole ke alakaʻi ʻana i nā dosis kiʻekiʻe.

Ke hoʻoneʻe nei i ka mea maʻi i Glyclazide mai kahi mākia hypoglycemic waha, ʻaʻole pono kahi manawa hoʻololi. I ka hihia o ka hoʻoponopono hou ʻana o kekahi hoʻomākaukau azi sulfonylurea me kahi hapalua hapalua ola (ʻo ka laʻana, ʻo chlorpropamide) me gliclazide, kiaʻi pono ka nānā ʻana i ke ʻano o ka mea maʻi e pale i ka hoʻomohala ʻana o kahi hopena hoʻohui a me hypoglycemia.

Inā pono, hiki ke kuhikuhi ʻia Gliclazide i ka hui pū me ka insulin, alpha-glucosidase inhibitors a me biguanides.

ʻO nā maʻi e lawe ana iā Glyclazide ʻaʻole i lawa ka kaohi o ka nui o ka glucose i loko o ke koko ke kuhikuhi i ka insulin. Pono e mālama ʻia ka lāʻau lapaʻau ma lalo o ka mākaʻikaʻi koʻikoʻi o kahi kauka.

Inā e poina ʻoe i ka pau aʻe o ka lā aʻe, ua pāpā ʻia ʻo ia e lawe i ʻelua pālua i ka lā aʻe.

Aia i ka pākuʻi metabolic o hoʻokahi (glucose koko, glycated hemoglobin) o ka mea maʻi, hiki ke hoʻoponopono ʻia ka nui o ka lāʻau i ka wā o ka therapy.

Nā hopena hopena

mai ka papa hana ʻana: ʻeha o ka ʻōpū, ke ahulau, a me ka constipation, nausea, huʻi (ke kaumaha o kēia mau ʻōuli e hoʻoliʻeke inā lawe ʻoe i ka lāʻau me ka meaʻai).
ma ka ʻāpana o ka ate a me ka pāpaona o ke akea: hoʻonui i ka hana o nā enzyme o nā pepela, jaundice cholestatic, hepatitis,
mai nā lālā hemopoietic: leukopenia, thrombocytopenia, anemia, granulocytopenia,
mai ka cardiovascular system: epistaxis, arterial hypotension, cerebrovascular insufficiency, arteritis, palpitations, heart failed, tachycardia, myocardial infarction, leg swelling, thrombophlebitis,
ma ka ʻāpana o ke kiko o ka hihiʻo: ka ʻike maka ʻana o ka ʻike (ma mua o ka hoʻomaka ʻana o ka mālama).
nā maʻi kūlohelohe: pruritus, erythema, hōʻeha ʻili (me ke ʻano o ka bullous a me ke ʻano maculopapular), urticaria, vasculitis allergic, angioedema.

Nā hōʻailona nui o ka hypoglycemia: nā hiamoe, ka palupalu, ke poʻo, ka manawa, ka palupalu, ka palupalu, ka palupalu, ka paresthesia, ka haʻalulu, ka haʻalulu, ka nausea, ka luaʻi. Hiki ke hōʻike ʻia i kēia mau ʻano. , ke kaumaha, ka nalowale o ka ʻike. Hiki i ka hypoglycemia ke alakaʻi i ka piko a me ka make. Ke hōʻike nei kekahi mau mea maʻi i nā hōʻailona o ka adrenergic counter-regulation: kahe ʻana, ka ʻili palipaka, palpitations, ke kaumaha, ke kahe nui o ke koko, ka angina pectoris, tachycardia, ka arrhythmia cardiac - ʻo kēia mau hōʻailona e nalowale ma hope o ka laweʻana i nā kao.

Ke keu

I ka hihia o kahi overdose, ulu pinepine ka hypoglycemia.

No nā maʻi maʻalahi, pono e hoʻonui ʻoe i ka nui o nā karapu i ka meaʻai, e hoʻemi i ka momona o Gliclazide a / a hoʻoponopono i ka meaʻai. A hoʻokō ʻole ke ʻano o ka maʻi i ka mea maʻi.

Hiki i nā maʻi hypoglycemic hopena ke hoʻohui pū me ka hoʻokahuli, coma a me nā maʻi neurological ʻē aʻe. Pono kēlā mau maʻi iā lākou e mālama koke i ka lāʻau lapaʻau.

Inā nānā a hoʻokū paha kahi comog hypoglycemic, kahi hōʻike intravenous o 50 ml o kahi papa o 20-30% o dextrose (glucose). ʻOi aʻe, pono kahi hana o ka hopena o ka dextrose o 10% e mālama i nā pae o ke koko ma mua o 1 g / l. Pono ka liʻiliʻi o ʻelua lā e nānā pono. Pono e mālama ʻia ka mālama ʻana me ka mālama a mālama i nā hana koʻikoʻi o ke kino.

ʻAʻole maikaʻi ka Dialysis no ka mea paʻa ka gliclazide i kahi nui i nā protein plasma.

Nā ʻōlelo kikoʻī

No ka hōʻalo ʻana i ka pilikia o ka hoʻomohala ʻana i ka lawaiʻa o ka hypoglycemic, pono ke koho pono ke kauka i ka nui o ka Glyclazide, hāʻawi i ka ʻōmomaʻi i nā ʻōmomaʻi maʻalahi no ka lawe ʻana i ka lāʻau, a me ka mālama pono ʻana i kēia mau ʻōlelo aʻo.

Hiki ke hoʻomāliʻi ʻia ʻo Gliclazide i kēlā mau maʻi e hiki ai ke hāʻawi aku i nā meaʻai maʻamau, me ka ʻaina kakahiaka. ʻO ka mea nui o ka kalaiwa o ka kalaiwa ma muli o ka hoʻonui nui o ka hypoglycemia inā ke kali ʻana i ka ʻai o ka meaʻai, ʻaʻole i lawa ka nui a i ʻole haʻahaʻa haʻahaʻa puʻupena. Ke hoʻonui i ka hopena o ka hypoglycemia me kahi meaʻai haʻahaʻa-helu, ka inu ʻona, ka hoʻokaʻina ʻana o kekahi mau lāʻau mai ka hui o ka sulfonylurea, a ma hope iho o ka lōʻihi o ka hoʻoikaika ʻana a ka lāʻau nui paha. Hiki i ke hypoglycemia ke hoʻohālikelike a koʻikoʻi loa, ka mea e pono ai ka hoʻokipa ʻana i ka mea maʻi a me ka hoʻomaka ʻana o ka glucose i kekahi mau lā.

Hiki i ka hypoglycemia koʻikoʻi ke lawe i ka lāʻau sulfonylurea. ʻO nā mea palupalu a hoʻonāukiuki i nā mea maʻi, nā poʻe ʻelemakule, nā mea maʻi me ka nele o adrenal (ʻelua a me ka lua)

Pono ka poʻe maʻi a me kā lākou mau ʻohana e wehewehe i ka pilikia o ke kūlana hypoglycemic, e haʻi i kā lākou mauʻeha a me nā ala e mālama ai, a e wehewehe pū hoʻi i nā kumu i manaʻo ʻia i ke kūkulu hou ʻana o kēia hoʻopiʻi. E hoʻomaopopo pono ka mea maʻi i ka pono o kaʻai, ka hoʻomaʻamaʻa maʻamau a me ka nānā pinepine ʻana i nā pae o ka glucose koko. ʻO nā mea maʻi me ka maʻi maʻi e hoʻomaopopo ʻia e pili ana i ka piʻi nui o ka hypoglycemia inā he pōloli, ka lawe ʻana i ka mea inu ʻawaʻawa a me nā lāʻau anti-inflammatory non-steroidal.

Hoʻomaʻamaʻa pinepine nā hōʻailona o ka hypoglycemia ma hope o ka ʻai ʻana i ka meaʻai me ka ʻai momona, e like me ke kō. ʻAʻole maikaʻi kēlā me nā mea aloha. ʻOiai ke kōkua mua ʻana o ka hoʻomaha, hypoglycemia e noho hou. Inā ʻike ʻia kahi mau maʻi koʻikoʻi a lōʻihi paha, ʻoiai hoʻi ma hope o ka hoʻomaikaʻi iki ʻana me ka hoʻonui ʻana i ka kalaiwa, e koi ʻia ka nānā ʻana, e komo ai ka hale mālama.

ʻO ka hopena o ka mālama koko glucose i ka wā o ka lāʻau antidiabetic e emi i lalo o ke kumu o kēia mau kumu: ka maʻi, ke maʻi ʻokiʻoki, ka hōʻemi, ka trauma, nā kūlana kaumaha. I kekahi mau hihia, pono paha ke koi ʻia o ka insulin.

ʻO ka hopena o nā papa Gliclazide, e like me nā lāʻau lapaʻau hypoglycemic waha e pau ana i ka wā. ʻO ke kumu o kēia kūlana ka mea i hoʻomau ʻia o ka maʻi maʻamau a i ʻole ka nāwaliwali i ka hōʻalo. Ua kapa ʻia kēia ʻano me ka nalowale o ka lua o ka hopena o ka hopena, i ka hoʻohālikelike ʻole i ka hopena o ka hopena i ka hoʻomaka ʻana o ka lāʻau. ʻO ka hopena e pili ana i ka nele o ka hopena hiki ke hana wale ʻia ma hope o ka hoʻoponopono ʻana a me ka nānā ʻana i ka mea hoʻomanawanui e pili ana i ka meaʻai.

I loko o nā mea maʻi me ka nele o ka glucose-6-phosphate dihydrogenase, nā lāʻau lapaʻau mai ka hui o ka sulfonylurea, me Glyclazide, hiki i ka hoʻomohala ʻana o ka anemia hemolytic. Ma kēia hoʻohālikelike ʻana, e noʻonoʻo e hiki i ke koho ke ʻano o ka maʻi lapaʻau hou me ka lāʻau lapaʻau o nā papa ʻē aʻe a i ʻole e hoʻopili iā Glyclazide me ka akahele loa.

I ka wā o ka hoʻohana ʻana o Gliclazide, pono ia i ka loiloi pinepine ʻana i nā hana o nā pūpū, nā ʻōpū, ka pūnaehana cardiovascular, a me ke kūlana ophthalmic. I ka loiloi ʻana i ke kūmole o ka nui o ke koko, e pono e ana i ke ana o ka maʻi o ka hemoglobin glycated (a i ʻole ka lolo i ka ʻaihue koko plasma). Eia kekahi, ʻo ka nānā ponoʻī ʻana i ke kaʻe o ka glucose e pono ai i ka mea maʻi.

Hoʻokomo i ka hiki ke lawe i nā kaʻa a me nā mīkini paʻakikī

ʻAʻole i pā ʻia ka Gliclazide a i ʻole ka hopena iki ʻia i nā hana psychophysical a kahi kanaka. Eia nō naʻe, i ka wā o ka mālama ʻana, ʻoi aku ka hoʻomaka o ka hoʻōla, nā mea hoʻokele o nā kaʻa a me nā poʻe e hana ana i nā ʻoihana ulia pōpilikia e makaʻala e pili ana i ka hoʻoulu ʻia ʻana o ka hypoglycemia.

ʻŌpū a me ka lactation

Aia nā liʻiliʻi o nā ʻikepili lapaʻau e pili ana i ka hoʻohana ʻana o gliclazide i ka wā hāpai. Aia kekahi ʻike e pili ana i ka hoʻohana ʻana o nā hoʻomākaukau ʻē aʻe sulfonylurea.

Ma nā noiʻi holoholona, ua hōʻike pono ʻia ka loaʻa o nā huakui reproduction ma kahi o nā nui o nā gliclazide.

Me ka mea nui, ʻaʻole ʻōlelo ʻia ka lāʻau lapaʻau no nā wahine hāpai. Eia naʻe, i mea e pale aku ai i ka hoʻopukapuka ʻana o nā maʻi congenital i loko o nā keiki, pono ka mālama pono ʻana i ka maʻi diabetes. ʻAʻole ke hoʻohana ʻia nā ʻoihana antidiabetic waha i nā wahine hāpai, ʻo ka insulin ka lāʻau o ke koho. Ke hoʻolālā nei i ka wā hāpai a inā loaʻa ka hānau ʻana i ka wā e lawe ana i ka gliclazide, paipai ʻia e hoʻololi i ka lāʻau lapaʻau ma ka maʻi o ka insulin.

ʻAʻole i ʻike ʻia inā komo ka lāʻau i loko o ka waiū o ka makuahine, e pili pū me kēia, ua hoʻohālikelike ʻia ʻo Glyclazide i ka wā lactation.

Hoʻohui nūhou

ʻO ka hoʻohana kuʻikahi ʻo ka miconazole ua contraindicated (i loko o nā ʻōnaehana dosic a i ʻole ke ʻano o ka gel no ke noi ʻana i nā membrane mucous o ka waha waha), ʻoiai e hoʻonui ana i ka hopena o ka gliclazide a, ma muli o ia, hoʻonui i ka hōʻeha o ka hypoglycemia koʻikoʻi, a hiki i ka coma.

ʻAʻole i koi ʻia nā hui:

ʻO ka phenylbutazone (ma nā hana inikua no ka hoʻohana ʻana i nā ʻōnaehana): hoʻonui i ka hopena hypoglycemic o ka sulfonylureas. Hoʻomaopopo ʻia kekahi lāʻau lapaʻau anti-inflammatory. Inā hoʻoholo ʻia ʻo ke kumu o ia hui, pono e ʻike pono ʻia ka nui o ka glucose koko, inā pono, e hoʻoponopono i ka nui o ka glyclazide (ma ke ke ʻano hui ʻana a ma hope o ka wehe ʻana o ka phenylbutazone).
ethanol: hoʻomaikaʻi nui i ka hypoglycemia a hiki ke kumu i ka comog hypoglycemic.No ka manawa o ka lapaʻau, pono ʻoe e haʻalele i ka hoʻohana ʻana i nā mea inu ʻawaʻī a lawe i nā lāʻau lapaʻau e pili ana i ka etanol.
danazol: loaʻa kahi hopena maʻi maʻi maʻi; ʻaʻole i ʻōlelo ʻia ʻo kāna keʻena i ka wā o ka hypoglycemic therapy. Eia nō naʻe, inā pono ka hoʻokele, e hoʻoponopono ʻia ka hopena o Gliclazide.

ʻO nā hui e koi ana i ka pālala:

nā kumuhana hypoglycemic ʻē aʻe (insulin, acarbose, biguanides), beta-blockers, angiotensin-hoʻohuli i ka hoʻohui o enzyme (enalapril, captopril), fluconazole, histamine H blockers₂-receptors, sulfonamides, non-steroidal anti-inflammatory drug, high-dosis chlorpromazine, monoamine oxidase inhibitors: hoʻonui i ka hopena hypoglycemic a hoʻonui i ka hopena o ka hypoglycemia. Kuhi ʻia ka mālama mālama glycemic a me ke koho ʻia o Gliclazide.
tetracosactide, glucocorticosteroids no ka systemic a me ka kūloko (intraarticular, subcutaneous, cutaneous, rectal) hoʻohana: hoʻonui i ka glucose o ke koko me ka hiki ke hoʻomohala i ka ketoacidosis (hoʻemi i ka hoʻokaʻawale ʻana i nā kākio). Pono ka mālama glycemic control, ʻoiai me ka hoʻomaka ʻana o ka maʻi hypoglycemic, a me ka hoʻoponopono hou ʻana i ka glycazide,
beta₂-adrenomimetics (terbutaline, salbutamol, ritodrine): e hoʻonui i ke kahe o ke koko, no laila pono ke nānā pono ʻia nā pae glucose koko. Pono ke koi aku o ka mea maʻi i ka insulin,
gliclazide a me nā kumulima sulfonylurea: hiki iā ia ke hoʻoikaika i ka hana o nā anticoagulants, e koi ana i ka hoʻoponopono hoʻoponopono ʻia.

Hoike e pili ana iā Gliclazide

Wahi a nā loiloi, ʻo Gliclazide kahi mea lapaʻau antidiabetic maikaʻi. I kēia manawa, hoʻohana pinepine ʻia nā derony o ka sulfonylureas o ka lua o ka hanauna, ʻoiai ua ʻoi aku lākou ma mua o ka hanauna i mua i ka hopena o ka hopena hypoglycemic, a hiki ke loaʻa i kahi hopena like i ka wā e kuhikuhi ana i nā ʻōkuhi haʻahaʻa. Eia kekahi, ʻoi aʻe nā kālā o kēia pūʻulu i kahi hopena i nā hopena hopena.

Hōʻike nā poʻe loea lapaʻau i ka manawa o ka biotransformation o gliclazide, hana pū kekahi metabolite, ka hopena maikaʻi i ka microcirculation. Ua hōʻike nā nui noiʻi e hōʻemi ka lāʻau lapaʻau i ka hopena o nā hoʻopiʻi o kā microvascular (nephropathy, retinopathy), ka hoʻomohala o ka angiopathy. Eia kekahi, hoʻomaikaʻi ia i nā mea kanu conjunctival, hoʻopau i ka vasis stasis. Ma kēia hiʻohiʻona, maikaʻi loa ke koho o Gliclazide no ka hoʻopiʻi ʻana i ka maʻi o ka maʻi maʻi e like me ka ʻoihana hoʻokaʻawale i ke ake a mua, nephropathy, retinopathy a me ka angiopathy.

Aia kekahi mau hōʻike i kahi mau makahiki (3-5 mau makahiki) ma hope o ka hoʻomaka ʻana o ka lawe ʻana i ka lāʻau lapaʻau, e hoʻemi ana ka naʻau. I ia mau pilikia, pono ke koho ʻana i kahi ʻoihana hypoglycemic hou.

Nā papa papa glyclazide

He mākaukau hypoglycemic no ka hoʻokūkū waha, ʻo ia ka mea o ka lua o ka hopena sulfonylurea, he ākea ka hopena o ka hopena pāpaʻi therapeutic. Loaʻa ka Glyclazide i ke ʻano o nā papa o 80 mg a 30 a me 60 mg me kahi kenekulia. Ua hōʻike ʻia ka lāʻau lapaʻau ka hopena o laila, no laila, kuhikuhi pinepine ʻia ia i hiki ke hoʻonui i ka glucose koko.

ʻO Glyclazide 30 mg nā papa i kahi pōʻai, pāpaʻi-cylindrical ʻano, aia kahi chamfer, ʻūnuʻa ka waiho a ʻulaʻula paha (ʻeleʻele a hina paha nā tint). ʻO ka make he 60 mg ʻoi ka pilikia. ʻO ka mea waiwai e gliclazide. ʻO keʻano o ka lāʻau lapaʻau:

gliclazide-30 a 60 mg

colloidal kaomi silika

sodium stearyl fumarate

Nā hōʻailona no ka hoʻohana ʻana

Hoʻohana nui ʻia ka lāʻau Gliclazide no ka maʻi type o ka lā 2 a me ka hyperglycemia. He mea kūpono kēlā i ka ʻala ma ka hopena o ka hana haʻahaʻa o ka mālama ʻana i nā meaʻai, nā ʻano no ka hoʻohaʻahaʻa ʻana i ka nui o ka leʻaleʻa a me ka hoʻomaʻamaʻa kino. Hoʻohana ʻo Glyclazide i ka pale ʻana i nā hoʻopiʻi o ka maʻi diabetes mellitus type 2: ka hoʻomohala ʻana o nā pathologies microvascular (stroke, myocardial infarction) a me nā mea maʻi microcirculatory (retinopathy, nephropathy).

Nā ʻōkuhi no ka hoʻohana ʻana iā Gliclazide

ʻO ka hoʻoholo ma ka nui o ka nui o ka nui o ka hoʻokomo ʻana me ka hyperglycemia i hoʻoholo ʻia ma ke kumu o ke ʻano o nā hoʻohālike: ka makahiki, ka nui o ka maʻi maʻi, a me ke kōpaʻa koko ma mua o ka ʻai a ʻelua mau hola ma hope o ka ʻai. ʻO ka papa ʻōlelo mua ʻia ʻo 40 mg me nā meaʻai. Hāʻawi ʻia kēia kapu i nā maʻi āpau, e komo pū me nā mea makua. ʻO ka inikua mua o kēlā me kēia lā he 80 mg. Eia kekahi, kau aku i nā ʻāpana, ʻokoʻa o 160 mg i kēlā me kēia lā. Hoʻolaha ʻia ka hoʻoponopono ʻia ʻana o ka dosis me ka manaʻo he ʻelua minuke ʻelua manawa ʻelua.

ʻO ka dosage ʻokoʻa loa - 320 mg. Inā hele ʻoe i ka lawe i ka lāʻau lapaʻau, ʻaʻole pono ʻoe e hoʻonui i ka maʻi i ka lā aʻe. ʻAʻole ʻokoʻa ʻē ka dosage no nā maʻi maʻi, a me nā poʻe maʻi me ka hala ʻole ʻole. ʻO ka lawe ʻana i ka lāʻau pono e hele pū me ka kaohi o ka glucose koko i mea e pale ai i ka hypoglycemia (hoʻonui i ka nui o ka glucose).

Glyclazide MV 30 mg

ʻO ka hoʻololi i ka hoʻokuʻu ʻia (MV) o Gliclazide ka mea hiki ke 30 a ka 120 mg. Hōʻike ka hana i ke kakahiaka me ka meaʻai. Inā kīhai ʻoe i ka lawe ʻana i ka lāʻau no ka hyperglycemia, pāpā ʻia ka uku ʻana ma ka hoʻonui ʻana i ka papaʻa aʻe i kahi lā aʻe. Hoʻoholo kū hoʻokahi ka hoʻoholo i ka dosage. ʻO ka ʻōlelo mua ma kahi o 30 mg. I ka hihia o ka nele o ka hopena, e piʻi mālie ka nui (hoʻokahi manawa i ka mahina) i 60, 90 a me 120 mg. Hiki ke hoʻohui pū ʻia ʻo Gliclazide MB me ka insulin. E noʻonoʻo kākou i kahi hoʻololi hoʻohālikelike mai ka lawe ʻana i ka mana ʻo Gliclazide 80 a i Gliclazide MV 30 mg ma hope o ka loaʻa ʻana o ke kō.

Nā ʻōlelo a ke kūʻai a me ka waiho ʻana

Pono e mālama i ka lāʻau lapaʻau i kahi wahi pōʻeleʻele me ka wai ʻole o ka mahana o kahi kiʻekiʻe o ke kiʻekiʻe o 25 kiʻekiʻe. Pono e pale ʻia Gliclazide mai nā keiki. ʻO ʻekolu makahiki ka ola. Hoʻokuʻu ʻia e ka papa lāʻau.

I loko o ka mākeke lāʻau lapaʻau kūloko he nui nā analogue o Gliclazide. ʻO kekahi o lākou he mea hoʻomehana ʻano like, hiki i kekahi ʻaoʻao ke hoʻokō i kahi hopena therapeutic like. ʻO nā lāʻau noiʻi aku nā mea like o ka lāʻau lapaʻau.

Kukuna Canon,
Glidia MV,
Makalei,
Gliklada
Glioral
ʻOlaka
Diabeton
Diabresid
Haʻi maʻi.

ʻO nā data Pharmacological o ka lāʻau

Hoʻoponopono ka hypoglycemic no ka hoʻokō waha. Hana ʻia kekahi huahana e like me kahi mea o ka lua o ka holony sulfonylurea. Kōkua i ka hana ʻana o ka insulin e nā ʻāpana pancreatic. Hoʻonui i ka paʻakikī o nā kōpili peripheral i insulin. Hoʻemi i ka manawa manawa ma waena o nā papaʻai a me ka hoʻomaka ʻana o ka hana insulin.

ʻO ka ʻimi a me ke ʻano hana o nā papa "Gliclazide"

Ke komo nei i ka ʻōpū, hoʻopau koke ka lāʻau i loko o kona ana. Ma hope o nā hola 4, 80 mg komo i ke kahe wai me ka pākahi hoʻokahi o ka lāʻau. Ma kahi o 100% e hui pū me nā protein koko. Kāha ʻia paha i ka palupalu a hana i nā metabolites ʻaʻohe ona hypoglycemic waiwai, akā hiki wale ke hoʻopilikia i ka microcirculation. Hoʻopau ia i ka urine i ka lā.

I ka hoʻomakaʻana o ka mālama ʻana, ua 80 mg ka manawa i kauoha ʻia i hoʻokahi lā. Hiki ke lawe ʻia ka nui loa 160-220 mg papalua i kēlā me kēia lā. Hainu nā papa ma mua o ka papaʻaina. Eia kekahi, kau ka dosage i ke ala o ka maʻi a me ka nui o ka hōʻino i ka pancreas. Hiki iā ʻoe ke kaʻana i ka hoʻokipa. Hoʻokahi papa papa ma luna o kahi ʻōpū ʻole, a ʻelua mau hola ma hope o ka ʻaina, e hana hou i ka dosis. Pehea e hoʻohana ai i ka "Glyclazide"? Nā ʻōkuhi no ka hoʻohana. Kūʻai, mea hoʻohālike, nā kūpono kūpono - e haʻi ke kauka e pili i kēia mau mea.

Hoʻopili pū me nā lāʻau ʻē aʻe

Ua pau ka hopena o nā papa Glyclazide i ka wā i lawe pū ʻia me kekahi mau lāʻau lapaʻau. ʻO kēia nā kumulā pyrazolone, nā lāʻau lapaʻau nā antibacterial sulfonamide, inhibitors MAO, theophylline, caffeine.

Me ka hoʻokūkū pinepine ʻana me nā beta-blockers koho-koho ʻole, hoʻomohala ʻia ka hoʻomohala ʻana o ka hypoglycemia, tachycardia a me nā lima haʻalulu, hoʻoulu ʻia, ma ka pō maoli, ʻike ʻia i ka pō.

Ke hoʻohana nei i ka lāʻau lapaʻau "Cimetidine" i loko o ka plasma, e hoʻonui ka hoʻonui o ka papa "Gliclazide". Hiki i kēia ke alakaʻi i ka hypoglycemia koʻikoʻi. Me ka hoʻokolohua hoʻohālikelike o nā papa Glyclazide a me ka lāʻau lapaʻau Veropomila, pono ia e kāohi i ke pae o ke kō koko.

Eia kekahi, me ka lawe ʻana i nā GCS, hōʻemi ʻia nā papa Glyclazide i ko lākou hypoglycemic waiwai. ʻO ia mau lāʻau like me ka diuretics, barbiturates, estrogens, a me kekahi mau lāʻau anti-TB. No laila, he mea kūpono e nānā i ka hoʻokolohua piha ʻana i ke kino ma mua o ka lawe ʻana i ka lāʻau lapaʻau "Gliclazide." ʻO nā ʻōkuhi no ka hoʻohana, ke kumu kūʻai, nā mea like, nā hopena hopena - pono ke ʻike ʻia kēia mea ma mua.

Nā hōʻailona no ka lawe ʻana i nā papa Glyclazide

Ua kuhikuhi ʻia ka lāʻau lapaʻau no ka mellitus o ka lua o ka ʻano o ka ʻāʻālua o ka maʻi, inā ʻaʻohe insulin e hilinaʻi nei. Pēlā nō hoʻi no ka pale ʻana no nā maʻi microcirculatory. Hoʻohana ʻia ka lāʻau lapaʻau ma lalo o ka nānā o kekahi kauka. ʻO ka mua ʻoe e lawe i kahi hōʻike koko koko. E noʻonoʻo pono a hahai i kahi papaʻai i ka wā o ka mālama ʻana, e hoʻemi i ka komo ʻana o ka paʻakai a me nā kālaiʻai. E hōʻole i ka lawe i ka palaoa a me ke kō.

Gliclazide mv

Ua hōʻoiaʻiʻo maikaʻi ʻo Glyclazide mv nāʻa iā lākou iho. E hōʻike nā ʻōlelo aʻoaʻo i ka hoʻohana e pili ana i nā contraindications a me nā hopena ʻaoʻao o kēia lāʻau lapaʻau. Hoʻohana ʻia e mālama i ka mellitus non-insulin-hilinaʻi me ka hōʻeha ʻeha. ʻAʻole hiki iā ʻoe ke inu i kēia lāʻau lapaʻau no ka maʻi maʻi o ka ʻano mua, me nā ala o nā puʻuwai a me nā pūpū. I ka wā hāpai a me ka lactation, lawe pio ka lāʻau.

Pono e mālama pū i ka mālama ʻana me ke kaohi gula. I waena o nā hopena hopena, ka nausea, ka luaʻi, ke kaʻa ʻana a me ka ʻeha i loko o ka ʻōpū e hiki ke ʻike. I nā hanana pinepine, ulu ka anemia a me ka leukopenia. Me kahi hopena kūlohelohe i kekahi mau papa papa, hiki paha ke loaʻa. ʻO Gliclazide mv ka nui o nā lāʻau lapaʻau me ka hoʻohui ʻole ʻana. He mau diuretics kēia, barbiturates, estrogens, nā lāʻau lapaʻau aminophylline. ʻOiaʻiʻo, pono e aʻo ʻia nā ʻōlelo hoʻohana no ka hoʻohana ʻana ma mua o ka hoʻomaka ʻana i ka mālama ʻana me nā papa Glyclazide mv. ʻAʻoleʻoi aku ke kumukūʻai o ka huahana ma mua o 500 rubles.

ʻO ka lāʻau lapaʻau hypoglycemic oral. ʻO nā papa keʻokeʻo, hāmeʻa convex. Ma nā ʻaoʻao ʻelua he mau hōʻailona o DIA 60. Hoʻomaopopo kēia i ka laikini. He ala maikaʻi kēia e hōʻike i ka lāʻau lapaʻau.

ʻO ka hoʻonohonohoʻana o ka lāʻau lapaʻau ke komo pū me ka mea waiwai gliclazide. Ke kuhikuhi ʻia nei ka lāʻau lapaʻau wale nō no nā pākeke. Pono ʻoe e inu i hoʻokahi papa i hoʻokahi lā. Hoʻohana maikaʻi ʻia kēia i ka wā kakahiaka. Aia i ka ʻano o ke maʻi maʻi a me nā kūlana maʻamau, hiki ke hoʻonui ʻia ka dosage i ʻelua papa o ka lā. ʻO nā papa ʻōlelo Glyclazide like like me ka nui o ka hoʻoponopono regimen. ʻO nā ʻōlelo ʻōlelo e hoʻohana ai e wehewehe i nā mea āpau ma nā kikoʻī.

Ke hoʻohana nei i kahi kiʻekiʻe o ka lāʻau, e ulu paha ka hypoglycemia. I kēia kūlana, hiki i ka wikiwiki ke noi aku i ke kōkua a me ka loea. Loaʻa ia nā contraindications like a me nā hopena ʻaoʻao e like me ka "Gliclazide mv" hoʻoponopono. Kahi ʻōlelo no ka hoʻohana ʻana, kumukūʻai, nā loiloi - pono e aʻo ʻia a pau ma mua o ka hoʻomaka ʻana o ka mālama ʻana.

Hōʻike i ka lāʻau lapaʻau "Gliclazide"

ʻO ka manawa pinepine, hiki iā ʻoe ke lohe i nā ʻōlelo maikaʻi e pili ana i nā pōpoki. Hoʻomaopopo nā mea maʻi e kōkua ka lāʻau lapaʻau i ka mālama ʻana i ke kō koko a kōkua i ke olakino maʻamau. ʻO ka mea wale nō e hopohopo nei e pono ke lawe pono i ka lāʻau lapaʻau e like me ka hoʻolālā. Hiki i ka overdose ke weliweli.

ʻO ke kumukūʻai o Gliclazide i nā lāʻau lapaʻau

Ua pau ka hoʻopaʻa inoa ʻana o ka lāʻau lapaʻau, no laila ʻaʻole maopopo ka kumu o Gliclazide. ʻO ke kumukūʻai o kekahi mau analogues:

ʻO Gliclazide MV - 115–144 mau rubles. nā pā paona o 60 papa o 30 mg pākahi, pākahi.
Glidiab - 107–151 mau rubles. nā pākaukau he 60 papa o 80 mg pākahi, pākahi.
Diabeton MV - 260–347 mau rubles. ma kēlā me kēia paona 30 mau papa o ka 60 mg.