Pākuʻi a me ke ʻano type diabetes 1 a me ka 2 kiʻina o ka hoʻouka ʻana, ka pūnaehana, nā hopena ʻaoʻao a me ke kumukūʻai
ʻO kahi mea loea, koho i kahi lāʻau lapaʻau no ka maʻi maʻi i ka mea maʻi, pono ke alakaʻi e ka helu o nā mea, e komo pū ana i ka makahiki a me ka paʻakikī o ke kaʻina pathological, ka hele ʻana o nā maʻi concomitant. Eia kekahi, e kau pono i ke ʻano o ka patology, e loli paha ke ʻano o ka mālama ʻana i ka maʻi.
Pono e hāpai i ka lawe wale ʻana i nā papa no ka diabetes mellitus e hiki ke hoʻokō i kahi hopena lōʻihi loa, ʻoiai pono e paʻakikī ka mālama ʻana i kēia ʻano. ʻO ka hoʻokō me kahi pākola therapeutic a me ke ʻano ikaika e lilo i mau mea nui.
I kēiaʻano, maʻi ka maʻi maʻi ʻaʻole hiki ke hoʻōla maikaʻi ʻia. Inā hāʻawi ʻia kekahi kanaka i kēia maʻi, ʻo ia ka mea e hoʻololi pono ʻoe i kou ala maʻamau i kahi ala hou a hahai mau iā ia.
Hāʻawi ka lāʻau olakino i kēia lā i nā lāʻau hou aʻe a nui hou aʻe i loaʻa ʻole nā hopena maikaʻi ʻole i ke kino o ke kanaka me nā lāʻau lapaʻau kahiko.
He aha ka maʻi?
Ma ke kaʻina o ka hoʻomohala ʻana o ka maʻi, hele ka lohi i nā pae kaʻina āpau i ke kino. ʻO ke kumu nui no kēia hana ʻole, ʻo ka pancreas e hana ana i ka nui o ka insulin o ka nui, e hoʻoponopono ana i ke kiʻekiʻe o ka glucose i ke koko.
I ka hopena, ʻaʻole hiki ke loaʻa i nā ʻāpana o ke kino ke ʻano pono o ka pono a me nā mea waiwai ʻē aʻe, a me ka nui o ka nui o nā hōʻailona gula e hōʻike ʻia nā maʻi ʻē aʻe o nā kino ponoʻī.
I kēia lā, ʻelua mau ʻano o nā maʻi:
- ʻAno maʻi type 1. ʻO ka hiʻohiʻona nui o kēia ʻano maʻi, ʻo ka hiki ʻole o ka pancreas e hana i ka insulin ma kāna iho. ʻO ia ke kumu, pono ka poʻe i ʻike i kēia ʻanololo (o ke ʻano mua) i nā inikini mau loa o ka hormone e mālama i kā lākou hana koʻikoʻi.
- ʻO ka maʻi diabetes type 2 ka mea maʻamau ke ʻano o ka maʻi. Wahi a nā helu loea, ʻoi aku ka nui o ka wahine i ka hoʻomohala ʻana i ka pathology ma mua o ke kāne. Eia kekahi, ulia nā ʻelemakule. ʻO ke kumu nui o ka hoʻomohala ʻana o kēia ʻano o ka papa hana o ka papaʻaina o ka hiki ʻole o ka pancreas e hana i ka insulin i ka nui o ka pono no ke kino.
I nā hihia koʻikoʻi loa, hiki i kekahi ʻano o nā pathology e like me ke maʻi gestational maʻi. ʻO nā kumu nui no kona hoʻomohala ʻana e komo pū me nā mea penei:
- ka wā hānau o kahi keiki i ka wahine,
- ka hoʻomohala ʻana o ka hyperglycemia.
ʻO nā kumu o ka hoʻolālā ʻana o ka maʻi e komo paha:
- genetic predisposition a hoʻoilina kuleana paha,
- momona momona a me ke kaumaha
- hopohopo nui a me ke kūlohelohe nui,
- kahi hana maʻalahi ʻole a me ka nele o ka hana kino,
- ka komo ʻana i loko o ke kino wahine o nā maʻi maʻi ʻehā.
Eia kekahi, nā kumu o ke hōʻike o ka maʻi e komo i nā mea like e like me ka makahiki, ka ʻola, ka hana maʻamau o ka pancreas, ka loaʻa ʻana o ka hoʻomaha kūpono.
He aha nā hōʻailona e hōʻike mai i ka hoʻomohala ʻana o ka pathology?
ʻAʻole he ʻano like ʻole o ka maʻi, e like pū ana nā hōʻailona o ka maʻi maʻi.
Ma ka maʻi diabetes o ka ʻano lua, ʻike ʻia nā hōʻailona mua loa me ka mea maʻi. Hoʻomaʻa pinepine nā ʻike a pau i ka wā e loaʻa ai ka maʻi i ka hoʻomohala ʻana.
Kekahi ʻano o kēia mau wā, hoʻokau pinepine nei a hoʻopili ʻia e nā koʻikoʻi mau ke kumu i ka nānā ʻole ʻana o kahi mea i nā hōʻailona mua o ka maʻi.
ʻO nā hōʻailona nui o ka hoʻomohala ʻana i ka maʻi maʻi i nā hana penei:
- ʻO ka paluhaluhi, ka nalowale o ka ikaika a me ke ʻano mau o ka hoʻoluhi ʻana, hiki ke lilo i mau hōʻailona mua e ʻike ʻia me ka maʻi maʻamau o ka lā 2. Ma ke ʻano he kānāwai, ʻaʻole ka waiho ʻana i kahi nāwaliwali i kekahi kanaka ma hope o ka hoʻomaha maikaʻi a me ka hiamoe.
- Ka ʻike ʻana o ka lethargy, ke hiamoe a me ka nalowale o ka ikaika ma hope o ka ʻai ʻana, kaomi maoli inā ua lilo kēia ʻano i mea maʻamau a hōʻike pinepine iā ia iho.
- Ka makewai mau ʻole, ka mea i hele pū ʻia me ka maloʻo nui loa i ka waha waha. Pono e hoʻomaopopo ʻia, ʻoiai e inu ana i ka nui o ka wai, ʻaʻohe hiki i ke kanaka ke hōʻino i kona make wai. ʻO ia kahi ʻano hōʻailona o ka diabetes mellitus type 2 i ʻike nui ʻia a pono e lawelawe ma ke ʻano he hōʻailona ka pono o ke kūkā pono i kekahi kauka.
- Ke koi pinepine nei i ka urinate a me ka nui o ka hoʻonuiʻana i ke kahe mai ke kino, e hōʻike ana i ka hiki ʻana o nā maʻi a me ka hoʻonāola wai.
- Hoʻopili ka paona nui i ke kūlike ʻole o ka glucose. ʻO ia ke kumu he momona nui kekahi o nā hopena koʻikoʻi e pili ana i ka hoʻomohala ʻana i ka maʻi. ʻO nā hōʻailona o ka diabetes mellitus type 2 hiki ke loaʻa i ka momona o ke kino ma ka ʻāʻī a me ka ʻōpū.
- ʻO ka nui o ke kahe koko maʻamau.
- Hoʻohālikelike nui i ka leʻaleʻa no nā lole momona a hoʻonui i ka makemake. I ka manawa like, ʻoiai e hoʻopau i ka meaʻai nui, hiki i ke kanaka ke hōʻemi i ko lākou paona.
- ʻO ka hōʻike o nā pilikia me ka ʻili o ka ʻili a me ka ulu kino o ke kūlana. Eia kekahi, hoʻohui pinepine nā wahine i ka ʻalāʻau āpau ma ko lākou mau kino, ʻoi loa ma ka palu. Eia kekahi, hiki i nā pustules a me nā kinikini ke piʻi ma luna o ka ʻili. I ka wā lōʻihi, ua loli ka ʻili ma nā pālima a me nā wāwae - e lilo lākou i callous a keratinized. Pono hoʻi e uku aku i ka hoʻololi ʻana o nā papa kuʻuna, kā lākou melemele a paʻakikī.
- ʻO nā poʻomanaʻo mau loa, hiki ke hele pū me ka maʻi a me ka luaʻi.
- ʻO kahi hōʻeha koʻikoʻi i ka hihiʻo.
- ʻO ka hiʻohiʻona o nā ʻeha ma nā ʻōpio a me nā kolohe.
- Ke kahe aku nei i ka urine no ka nānā ʻana, hiki i nā hopena ke hōʻike ma mua o ka acetone.
- Aia nā pilikia me ka pōʻai kāne.
ʻOiai nā kumu i hoʻonāukiuki i ka hoʻomohala ʻana o ka maʻi, inā e ʻike ʻia kēlā mau hōʻailona, pono ʻoe e kamaʻilio i kahi keʻena olakino a loaʻa i nā haʻawina pono.
He aha ka lapaʻau lapaʻau o nā ala?
Ke kuhikuhi ʻia aku nā lāʻau lapaʻau no ka mālama ʻana i ka maʻi diabetes i ka wā ʻaʻole hua lāʻau lapaʻau (ʻo ia hoʻi, ʻo ka mālama ʻana i kaʻai a me ka hana kino) ʻaʻole ia i lawe i ka hopena kūpono.
Mamuli o ka mea i loaʻa ʻole ka hewa i ka pancreas, ʻaʻole hiki ke hoʻonui ʻia ke kaila o ke koko me ka ʻole o ka wawao o ke kauka.
I kēia mau lā, aia he nui nā papa lāʻau ʻoneki e hoʻohana ikaika i ka glycemia.
Hiki ke hoʻokaʻawale ʻia lākou a pau i kekahi mau pūʻulu a hoʻohana ʻia nā mea pili i ke ʻano o ke ʻano o ka maʻi i loko o kahi maʻi maʻi.
- ʻO nā keʻena a nā maʻi lapaʻau nā lāʻau lapaʻau e kōkua i ka hoʻoulu ʻana i ka mea huna o ka insulin hormone. Kuhi pū kekahi pūʻulu o nā lāʻau i ʻelua mau pūʻulu nui - sulfonylureas a me meglitinides.
- ʻO ka Sensitizers nā lāʻau lapaʻau maʻi e loaʻa ai ka hopena maikaʻi loa i ka hoʻonui ʻana i ke ʻano o ka huina a me nā ʻāpana o ke kino i ka insulin i hana ʻia e ka pancreas. ʻO ia nā peni maʻi maʻamau e hoʻohana pinepine ʻia i ka hoʻomohala ʻana o ka kū i ka insulin. Kuhi pū kekahi pūʻulu lāʻau i nā mākaukau o ʻelua mau pūʻulu - biguanides a me thiazolidinediones.
- ʻO nā lāʻau lapaʻau no ka maʻi maʻi, ʻo ia nā alpha-glucosidiaz inhibitors, ke kuleana no ka hoʻoponopono a me ka hana ʻana pono maʻamau i nā hōʻea kino i loko o ka pākia, a me kā lākou excretion. ʻO ka lāʻau lapaʻau no ka maʻi maʻamau, ʻo ia ka mea nui i kēia hui, ʻo ia ʻo Acarbose.
- ʻO nā hua maʻi o ka maʻi āpau hou, he kōkua i ka hana o ka insulin a ma ka manawa like ke pale i ka hana o ka glucogen.
Nui nā lāʻau lapaʻau hou i hoʻohana nui ʻia a ʻaʻole paha he hopena maikaʻi loa i ke kino o ka mea maʻi (ma ke ʻano o nā ʻano ʻano like ʻole) ka mea nui loa. Kuhi i ka mea o kā lākou hoʻohana ʻana e pono ai i loko o ke ola holoʻokoʻa, he nui nā mea maʻi e hikiʻole iā ia ke hoʻolilo i kēlā maʻi maʻi hou i kahi lāʻau hou. ʻO ia ke kumu i hoʻohana pinepine ʻia ai nā lāʻau lapaʻau ʻano type 2 i ka hui o ka sulfonylurea a me nā pūʻulu derivative biguanide. Ma ke ʻano he kānāwai, he haʻahaʻa ka haʻahaʻa o nā lāʻau maʻi maʻi a kōkua e hoʻokō i ka pae i koi ʻia o ka glycemia.
Eia kekahi, hiki ke mālama i ka mālama lāʻau lapaʻau i ka hoʻopihapiha ʻana i ka mālama ʻana i nā lāʻau lapaʻau mai nā hui like ʻole (nā ʻōkuhi o ka maʻi diabetes no ka hoʻohana) e hoʻokō pono i kahi hopena maikaʻi aʻe.
Nā lāʻau lapaʻau mai ka pūʻulu o nā derivatives o ka sulfonylurea
Ua hoʻohana ʻia nā derfatives o Sulfonylurea i nā lāʻau lapaʻau e hoʻohaʻahaʻa i nā glucose koko.
Pili ka hopena o kēia pūʻulu o nā lāʻau lapaʻau ma ke kino o ke kanaka me ke ʻano o ke kaʻina o nā pupu beta pancreatic, ka mea e kamaʻilio pū me ka hoʻoulu ʻana a hoʻonui i ka hana o ka insulin endogenous.
ʻO ka hoʻohanaʻana i nā derivatives o ka sulfonylurea e hele ana i mua o ka maikaʻi o ka hoʻonela beta paʻa i ke kino.
ʻO ka hana o kēia ʻano o nā lāʻau lapaʻau ka mea e hōʻike ai i nā hopena aʻe:
- ka hoʻowalewale ʻana i nā ʻōnaehana beta pancreatic a me ka hoʻonui ʻana i kā lākou naʻau ma ka cellular levelular
- hoʻonui i ka hana o ka insulin a me ka pani ʻana o ka hormone e wāwahi iā ia (insulinase) ꓼ
- nāwaliwali i ka pilina o ka insulin a me ka protein, e hōʻemi ana i ka pae o ka insulin e hoʻopaʻa ana i ka antibodiesꓼ
- komo i ka hoʻonui i ka mahele o ka naʻau a me ka lipid tissue e hele aku i ka insulinꓼ
- hoonui i ka nui o nā mea i hāʻawi ʻia i ka insulin i ka membranesꓼ tissue
- Kōkua i ka hoʻomaikaʻi ʻana i ka hoʻohana ʻana i ka glucose i loko o ka naʻau a me nā kalamu
- hoʻoliʻiliʻi glucoseoneogenesis ma loko o ka ate
- i ka lipid tissues hoʻoulu i ka lipolysis a hoʻonui hoʻi i ka nui o ka hoʻihoʻi ʻana a me ka hoʻihoʻi o ka glucose.
I kēia manawa, nui nā ʻano hua lāʻau i loaʻa mai ka sulfonylurea.
ʻO nā lāʻau lapaʻau o ka pauku mua, ka mea i hoʻohana ʻole ʻia i ka lāʻau lapaʻau o kēia wā, ʻo ia ʻo Tolazamide, Carbutamide. Ua lilo lākou i mau ʻelele o ka sulfonylurea i ka hoʻomaka ʻana o ka iwakāluakūmālua, akā ma muli o ka nui o nā hopena maikaʻi ʻole e hoʻokō ana i nā kino āpau a me nā ʻōnaehana o ke kanaka, ʻaʻole lākou i hoʻohana hou ʻia e nā lāʻau lapaʻau hou.
ʻO ka papa ʻelua, ʻo Glibenclamide, ʻo Gliclazide a me Glipizide he mau ʻelele. Kēia mau lāʻau lapaʻau i kuhikuhi ʻia i nā mea maʻi e hoʻohaʻahaʻa i ko lākou koko koko. Ke hoʻohana nei i kēlā mau lāʻau lapaʻau, pono e nānā pono i ke kūlana o ka glycemia, no ka mea, i kahi koho kūpono ʻole ke hoʻolilo i ka hoʻomohala ʻana o ka hypoglycemia. No ka māhele o ke kolu ʻo Glimepiride.
He aha ka maʻi diabetes
ʻO kēia ka inoa o nā pūʻulu o nā maʻi o ka pūnaehana endocrine, ma kahi o ka hana o ka hōʻemi ʻana o ka hoʻoneʻe o ka hormone a ua loaʻa i kahi nui o ka glucose i ke koko. I kēia lā, ua hoʻokaʻawale ʻia nā ʻano ʻelua o ke ʻano maʻi maʻi:
- ʻO ke ʻano mua (DM 1) - ke ʻano hilinaʻi nei kēia ʻano, kahi i hana ʻole ʻia ka hormon a i ʻole ka synthesized i ka nui o ka nui ma muli o ka make ʻana o nā cell beta. Kuhi ʻia kēia ʻano ma ka 5-10% o nā maʻi āpau. ʻO ia nā kamaliʻi a me nā ʻōpio.
- ʻO ke ʻano lua (type 2 diabetes) kahi ʻano kūʻokoʻa kūmole i hopena mai loko mai o ka hōʻino ʻana o ka hoʻopili ʻana i nā pūnaehana kino o ke kino me ka insulin a i ʻole kahi ʻāpana hōʻeuʻeu o kāna mea hilo i loko o nā puna o ka pancreas. ʻO nā kānaka ma luna o ka 35 he mau makahiki e loaʻa iā ia, 90% o lākou he mau maʻi maʻi makua ma mua o 50 mau makahiki.
I kahi kūlana e kau ʻia nā kōmela koko
Hiki i ka poʻe maʻi e hōʻeha ana i ka maʻi diabetes type 2 ke hele me nā wai ʻole e hoʻohiolo i ke kō. Mālama lākou i nā pae o ka glucose i loko o nā palena maʻamau ma muli o ka nui o ka hana pilikino a me ka ʻai me ka liʻiliʻi o nā mea kākena. I nā maʻi he nui, ua emi nā keʻena o ke kino, no laila pono ʻoe e hoʻololi e lawe i nā lāʻau lapaʻau. Ua kau ʻia lākou i ka wā, ʻoiai me ka mea ʻai, hoʻomau ʻia ke kōpaʻa no 3 mau mahina. Hoʻoholo ʻia nā ʻano kūpono o ka mālama ʻia e pili ana i nā ʻano pilikino o kēlā me kēia maʻi, i ka nānā ʻana i nā kikoʻī āpau.
ʻO ka pahuhopu o ka lapaʻau e hoʻihoʻi i ka pancreas, hoʻōla i nā kaʻina metabola a hoʻemi i ka pane ʻana mai o ka nui o nā ʻōnaehana o ke kino o ka insulin. No ka hapanui o nā maʻi, ʻo ka pauna i ka lāʻau diabetes i ka metformin e hoʻohālikelike ʻia. Hoʻonohonoho maikaʻi ia i nā kiʻekiʻe o ke kō, hāʻawi i ka hoʻohaʻahaʻa ʻana a he ʻemi iki ka hopena. Hiki ke hoʻokaʻawale ʻia nā ʻina āpau o ka mālama ʻana i ka maʻi diabetes 2 e holomua:
- ka mea mua, he meaʻai meaʻai,
- ʻo ka lua ua Metformin i hui pū me nā meaʻai,
- ʻo ke kolu ʻo Metformin i loko o ka mālama paʻakikī me ka hoʻohana ʻana i ka meaʻai a me ka hoʻomaʻamaʻa ʻana,
- ka ha he kīʻaha i ka hui pū ʻana me ka hoʻomaʻamaʻa ʻana a me ka mālama ʻana i nā lāʻau lapaʻau paʻakikī.
Ke lāʻau lapaʻau no nā maʻi maʻi type 2
Aia nā loaʻa nā papa kōnane e hoʻohiolo ai i ke ʻano maʻi type 2. Ua māhelehele ʻia lākou i mau pūʻulu e pili ana i ke kumu o ka hana ma ke kino. Wahi a kēia koi, hiki ke hoʻokaʻawale nā ʻano i kēia mau lāʻau lapaʻau:
- Nā mea paʻa o ka glucosidase Alpha. ʻO kēia ʻāpana o nā lāʻau antidiabetic ma waho o ka spra o ka hoʻoponopono ʻana i ka hormonal o nā metabolism ka pakanā ma muli o ke kuapo ʻana i ka hinuhinu o nā haʻalulu mai ka ʻawaʻawa. 2 ke kūkaʻi nei nā lāʻau lapaʻau ma aneʻi - Acarbose, Forsig, Vipidia a me Miglitol.
- Nā Kūlana. Kēia pūpū hui āpau e pili ana i ka sulfonylureas a me nā meglitinides. Hoʻonui lākou i nā hana hana insulin. Hanaʻo Meglitinides (Novonorm) i kēia wikiwiki, akā, ʻaʻole e mau i ka wā e like me ka sulfonylureas (Glurenorm, Diabeton).
- Nā ʻōwili. ʻO kēia nā papa mai kahi hanauna hou o ke kō. ʻO kēia ka melepidyl peptidase 4 inhibitors a me nā glucagon like me ka peptide 1 receptor agonists. I kēia hui, ua hāʻawi ʻia nā lāʻau lapaʻau ʻo Januvia, Liraglutid, Exenatide.
- Nā mea ʻike. ʻO kēia pūʻulu o nā lāʻau lapaʻau e hoʻonaninani i nā ʻili i ka insulin. ʻElua mau subtypes o nā papa i ʻokoʻa ma kēia: thiazolidinediones (Actos, Avandia) a me biguanides (Metformin, Siofor, Bagomet).
Hoʻomākaukau Sulfonylurea
Kuhihewa ʻia kēia mau papa he mau mea huna. Ua hoʻohana ʻia nā derfatives o Sulfonylurea mai 1955. I kēia mau lā, aia kēia mau lāʻau i ʻekolu mau hana o ka hana:
- hoonui i ka huna huna e nā kanaka pancreatic,
- ho'ēmi i kā lākou hana momona glucagon,
- hoʻonui i ka pilina o nā mea pale aku o ka ʻenekini kūpono no ka insulin.
Ke hōʻike nei no kā lākou hoʻohana ʻana nā non-insulin-depend-diabetes mellitus (NIDDM), kahi e lawe ʻole ai ka meaʻai a me ka hoʻoponopono regimen i kekahi hopena maikaʻi. He mea kūpono ia e ʻike ai i ka nui o nā derivatives o sulfonylurea e hoʻonui i ka hopena o ka hypoglycemia a kōkua i ka loaʻa kālā. Eia kekahi, loaʻa iā lākou kekahi mau hopena maikaʻi ʻole:
- nā pepeke
- wahawa
- leo koma
- hepatotoxic mau hopena
- kue
- blockade nā pā o potassium me ka myocardium.
ʻO kēia lāʻau hypoglycemic mai ka lua o ka hui sulfonylurea kūloko i hoʻohana maikaʻi i ka hana mua o ka hana hana insulin. ʻO ka mea hoʻohana i ka gliclazide. Hoʻemi ia i ka manawa mai ka ʻai ʻana i ka hoʻouka insulin.ʻO ka hopena, ala ka manaʻo o ka hormone ma mua o ka pāʻina a i ʻole ka momona ukana. Eia kekahi, ʻo ka lāʻau lapaʻau he mau hana penei:
- hemovascular
- antioxidant
- moʻoʻala.
Paʻi ʻia ka maʻi Diabeton e hoʻemi i ka pae o ka kolamu ma ke koko a me ka palupalu i ka pāʻai, paipai i ke kahe koko i loko o nā kīʻaha liʻiliʻi. ʻO nā hiʻohiʻona nui o ka lāʻau lapaʻau:
- Nā hōʻailona no ka hoʻohana ʻana. Kāhea 2 diabetes mellitus i ka hala ʻole o ka hopena o ke kaupaona ʻana.
- Nā hopena hopena. i ka pale hewa ʻana o ka reimen dosing, ka pōloli, ka ʻeha, ka ʻōpū, ka aphasia, ka mea hoʻopaʻapaʻa, ka hopohopo, a me ka insomnia ka mea.
- Nā Hoʻohui Hoʻohui lākou i ka ketoacidosis, nā hōʻeha a me nā ʻinoʻino paha, coma, precoma diabetes, ʻo ka hānau ʻana, ka maʻi diabetes type 1.
Hoʻokomo ʻia ka lāʻau lapaʻau e pili ana i ka glimepiride, kahi mea e hoʻohaʻahaʻa i ke kao o ka glucose i loko o ke koko. ʻO ka hana o ka hana ke hoʻokuʻu i ka insulin mai nā cell beta pancreatic. ʻO kahi hopena, e hoʻomaikaʻi ka paneʻana o ka glucose. Hōʻike ka hoʻohanaʻana o Amaril i ka maʻi diabetes type 2. Hiki nō ke hoʻohana pū i ka hana hui me ka metformin a i ʻole insulin. ʻO nā hoʻohālikelike no ka hoʻohana ʻana:
- huakini a me ka hana lima,
- nā makahiki o nā keiki
- hoʻoweliweli a ʻokoʻa ʻole i ka lāʻau lapaʻau,
- ʻAno maʻi type 1
- hapai, lactation,
- precoma, coma, diabetes ketoacidosis,
- ka predisposition hoʻoilina i nā maʻi ʻeha.
Hiki i nā hana amaril ke hoʻopili pū me nā hopena kūpono ʻole e pili i ka aneane o nā ʻuhane āpau. ʻO nā hopena nui, ka:
- ninini
- utuka
- mea momona
- manaʻo ʻino
- lie kanikela
- pololi
- hilahila.
ʻO ka lāʻau ikaika loa e pili ana i ka glibenclamide, ka mea e hoʻoikaika i ka hana o ka insulin a hoʻonui i ka hopena-hoʻokuʻu i ka insulin. Ma muli o kēia, ua manaʻo ʻia ka lāʻau lapaʻau e ʻeha. Eia kekahi, ʻo kēia mau maʻi maʻi diabetes i kahi hopena cardioprotective a me nā hopena antiarrhythmic. ʻO nā nuances koʻikoʻi āu e pono ai e ʻike i ka wā e lawe ai i kēia lāʻau lapaʻau.
- Nā hopena hopena. ʻO nā ʻano maʻi, ka loaʻa ʻana o ka paona, ka maʻi, ka cholestasis, arthralgia, nā maʻi neurological.
- Nā Hoʻohui Hoʻokomo lākou i ka comos hyperosmolar, ketoacidosis, coma, coma, type 1 diabetes, ʻoki kuni, hōʻeha, hōʻeha, leukopenia.
ʻO kahi hiʻohiʻona o kēia lāʻau lapaʻau he kina hepatic. Ma kahi kokoke o 95% o ka lāʻau lapaʻau i lawe ʻia ma loko o ka bile. No kēia kumu, ʻaʻole pono ka hoʻoponopono ʻana o ka maʻi maʻi i nā mea maʻi me nā maʻi o ka maʻi. Hoʻomaopopo ʻia ka lāʻau lapaʻau no nā mea nona ka hana a me ke kino e hiki ke hoʻoponopono i ka pae glucose. Ma mua o ka hoʻohana ʻia, pono e aʻo ʻia i nā ʻano koʻikoʻi o Glycvidon:
- Nā hopena hopena. i nā hanana pinepine, hypoglycemia, allergies, dyspepsia, ua hoʻomaopopo ʻia nā loli i loko o ke ʻano o ke koko.
- Nā Hoʻohui Hoʻopili kēia ma ka lolo 1, ka maʻi maʻi kipa, ka hapai, ka lactation, ka manawa ma mua o ka hōʻemi, ka acidosis, precoma.
Meglitinides
ʻO nā subspecies puka lua o nā ʻekikekau he meglitinids, me nā repaglinides a me nā nateglinides. Hāʻawi ʻia kēlā mau lāʻau maʻi maʻi e ka wikiwiki o ka hana. ʻAno ke hoʻomākaʻi i nā lāʻau pili i ka hyperglycemia postprandial, i.e. kaupaʻa kōpae ma hope o ka ʻai ʻana. Hiki iā lākou ke lilo i loko o ka poʻe me kahi meaʻaiʻai ʻole. ʻO nā papa mai kēia pūʻulu he mau hemahema:
- i kekahi manawa kumu i ka hypoglycemia,
- pono ʻoe e hoʻohana i nā kīʻaha he nui;
- he kumukūʻai
- Hoʻohana i ka hoʻoili paona,
- ʻaʻole i ʻike e pili ana i ka hana lōʻihi a me ka palekana.
Hoʻokumu kēia lāʻau lapaʻau i ka repaglinide, ka hopena o ka mea i hōʻike wale ʻia inā e hoʻokiʻekiʻe ʻia ka nui o ke kō. Hoʻihoʻi i ka lāʻau lapaʻau i ka hoʻomaka mua o ka hana huna o ka insulin (hana iā 3-5 mau ʻoi aku ka ikaika ma mua o nā derivatives sulfonylurea). Ke emi nei ka nui o ka glucose, e nawaliwali ka hopena o ka repaglinide. Me ka hoʻohiolo maʻamau o ke kō, ʻaʻole e loli ka mea huna hona. Hoʻomaopopo ʻia nā papa no ke ʻano maʻi type 2, e noʻonoʻo ana:
- Nā hopena hopena. ʻO ka coma hypoglycemic comal, vascular a me nā puʻuwai puʻuwai, urticaria, maʻi o ka maʻi, a luaʻi, vasculitis a hiki paha.
- Nā Hoʻohui. ʻAʻole hiki iā ʻoe ke hoʻohana i ka lāʻau lapaʻau no nā maʻi maʻi, ketoacidosis maʻi, type diabetes 1, hypersensitivity, hana maʻi lēʻaleʻa, maʻi koma.
Kūkulu ʻia kēia lāʻau lapaʻau ma nateglinide, kahi kahi phenylalanine. Hoʻihoʻi ka waiwai i ka huna mua o ka insulin. ʻO ka hopena, kōkua ka lāʻau lapaʻau e hoʻemi i ka nui o nā glucose i ka manawa koke ma ka ʻai. Kuhi ʻia kēia ʻano ʻike i ka maʻi diabetes type 2. He hōʻailona kēia no ka hoʻohanaʻana o Starlix. Ma mua o ka hoʻomaka ʻana o ka hoʻōla, pono ʻoe e aʻo:
- Nā Hōʻailona huhū Hiki i ka mahana lou, hoʻoluʻu, nā kuʻuna, hoʻonui nui i ka momona, nāwaliwali, hilo.
- Nā Hoʻohui ʻO kā lākou papa inoa kahi papa maʻi type 1, ka wā kamaliʻi, lactation, ka maʻi ketoacidosis maʻi, nā wahine hāpai, a me ka pono o ka ate.
ʻO kēia papa o nā paila maʻi maʻi mai ka hui sensitizer. ʻAʻole pili lākou i ka pancreas. ʻO kā lākou hana, ʻo ke hoʻokuʻu ʻana i ke kōpaʻa mai ka ate, ka mea e hoʻopili ai i ka hoʻowalewale maikaʻi a me ka neʻe ʻana o ka glucose i nā puna a me nā kiko o ke kino. Aia i ka hola 6-16. ʻO nā mea pono nui o kēia papa o nā lāʻau lapaʻau:
- lipid profile holomua,
- ka hiki ke pale i ka hoʻomohala ʻana o ka infococion myocardial i ka poʻe lohi,
- haʻahaʻa haʻahaʻa o hypoglycemia,
- ke kumu kūʻai
- aole e pili i ka paona.
ʻO ka maʻa o ka hana o ka me ke ʻano nui o ka metformin ʻaʻole i hoʻopili ʻia. Ua manaʻo ʻia, inā ʻike ka hopena, ke hoʻonui ʻia ka hoʻohana ʻana o ka glucose i nā kiko, ua māhuahua ke komo ʻana mai loko mai o ka ʻōpū o ka gastrointestinal tract, ua kāohi ʻia ka glucogenesis i loko o ka ate a hoʻopili ʻia ka hopena o nā papa o ke kūlohelohe o peripheral no ka insulin. Ke hōʻike nei i ka hoʻohana ʻana:
- NIDDM palapū i nā maʻi me ka hyperlipidemia a me nā momona nui.
- kinomi hōkūkū kinehu
- linaki ʻaʻanima X.
ʻO ka Metformin ka lāʻau lapaʻau wale nō i hōʻike i nā mea i hōʻike ʻia ma ka maʻi me nā NIDDM. Noho ia he kikowaena ma ka mālama ʻana i kēia maʻi. ʻO Metformin ka koho koho mua no ka maʻi diabetes a me ke kūlana prediabetic. ʻO nā ʻōhumu i kona hoʻokipa ʻana:
- ʻōpala lolo
- kepiko i ke ketoacidosis,
- Hoʻoulu ma hope o ka ʻoihana.
Ua hoʻokumu ʻia nā lāʻau lapaʻau Siofor 500/850/1000 e pili ana i ka metformin. Ke pale nei ka lāʻau lapaʻau i ka hoʻopili ʻana o ka glucose mai ka huihui. Hoʻolima pinepine ʻia no nā poʻe me ka nui o ke kaumaha o ke kino, no ka mea, he kōkua nā peni e hōʻemi i ke kaumaha. He nui nā contraindications i ka lāʻau, kahi āu e pono ai ka familiarize iā ʻoe iho me ka mua. Nā hopena maikaʻi loa o Siofor:
- ʻili metala
- nā pepeke
- lilo ka momona
- utuka
- anemia megaloblastic,
- ʻeha ka ʻōpū
- nā ninia
Thiazolidinediones
Kūkā hou kēia ʻano lāʻau lapaʻau. ʻO kā lākou hana he hoʻopilikia i nā mea nānā aku o ka peroxisomal. ʻO ka hopena - hoʻomaikaʻi i ka hoʻoneʻe a glucose e nā ʻōpala a me kahi hoʻohaʻahaʻa i ka hoʻokuʻu ʻana o ke kō mai ka momona. ʻO ka ʻokoʻa ma waena o kēia papa o nā papa mai biguanides kahi papa inoa nui loa o nā hopena ʻaoʻao ma ke kumukūʻai kiʻekiʻe. ʻO nā pono e loaʻa:
- ka hōʻemi ʻana i ka hopena o ka hoʻopiʻi macrovascular,
- ka liʻiliʻi o ka hopena o ka hypoglycemia,
- pale ʻia o nā ʻāpana beta o ka pancreas.
Hoʻohana ʻia nā papa maʻi diabetes kolohe e like me ka hui ʻana a i ʻole monotherapy no ka maʻi maʻi 2. ʻO ka inoa ʻoihana honua ʻo Pioglitazone. ʻO ka mea hana he agonist gamma receptor punahele maikaʻi loa. Kuhi ʻia ka ʻike ʻoi loa o ka waiwai hana ma hope o nā hola 2-4. Ma waena o nā hopena ʻino, ʻo ka hypoglycemia, ke kuʻi ʻana a me ka hoʻolilo ʻana i ka hemoglobin e hiki. ʻO nā hoʻohālikelike ʻana i ka lawe ʻana i nā papa:
- maʻi maʻamau ketoacidosis,
- hōʻeha paʻa ka naʻau
- a emi mai ma mua o 18 mau makahiki
- ʻAno maʻi type 1.
ʻO ke kumu o nā papa no ka maʻi Avandia e maʻa rosiglitazone, e hoʻonui ai i ka hoʻowalewale o nā ʻine i nā insulin. E pale i kēia kiʻi, aia ka hopena o ka glucose koko. Loaʻa ka bioavailability piha o ka waiwai i loko o 1 mau hola ma hope o ka hoʻokele ʻana. Hiki ke hoʻohana ʻo ia i ka mea hana e like me ka hui hui me ka derogative sulfonylurea a i nā metformin. ʻO nā hoʻohālikelike:
- maʻi diabetes type 1
- hapai
- hōʻeha a paʻakikī paha ka maʻi hana ʻana i ka nuku.
- makahiki keiki
- lactation.
Itors-glucosidase pale
ʻO ka waiwai nui o kēia māhele o nā papa, ʻo ia ka poloka o ka hana o kahi hoʻoneʻe o ka ʻono o ka waiʻawa e hoʻoneʻe i nā ʻaloli paʻakikī. ʻO ka maikaʻi o nā inhibitors ka aneane pau loa o nā hopena ʻaoʻao. I waena o kēia mau papa maʻi diabetes i waho:
- Hoʻopuka. Hoʻohana ʻia ia no ka hoʻonui nui ʻana o ka holi ma hope o ka ʻai ʻana. Hoʻohui - hāʻawi kālā maikaʻi maikaʻi. Ke hōʻike nei no ka hoʻohana ʻana he lāʻau hoʻohana hou me ka meaʻai haʻahaʻa-haʻahaʻa. I ka wā o ka mālamaʻana, flatulence, ʻeha, maʻi a me nā loli. ʻAʻole hiki iā ʻoe ke lawe i Glucobai me ka loaʻa ʻole o ka pilikia ʻole, nā maʻi gastrointestinal, hapai, lactation.
- Miglitol. Hoʻohana ʻia no ka maʻi maʻi mole 2 ʻano. Hiki i nā maʻi pākēneka ma hope o ka lawe ʻana i kēia mau lāʻau lapaʻau. ʻO nā contlines nā hernias nui, nā maʻi pākia, ke keiki a me ka wā hāpai.
Nā Kahu Inoa ʻo Dipeptidyl Peptidase
Ua kapa ʻia kēia mau huahana hou i mau huaʻāina. ʻO kā lākou hopena e hoʻonui ai i ka hana o ka insulin e mālama i ke kaona o ka glucose. I loko o kahi kino olakino, kahi ma ka 70% o kēia hormone e hana ʻia ma lalo o ka mana o ka pisa. Eia kekahi, hōʻemi lākou i ka momona. ʻO nā pono o kēia māhele o nā lāʻau lapaʻau:
- Ka hoʻomaikaʻi hoʻomaikaʻi Beta ʻana
- ka nui o ka emi ana o ka hookeai kiu,
- ka nele o ka hopena ma ke kaumaha o ke kino,
- haʻahaʻa haʻahaʻa o hypoglycemia.
ʻO kēia nā papa pani i hoʻohuiʻia. ʻO ka mea hana e neʻe ai i loko o ka mea i kahi sitagliptin i ka hoʻopaʻa ʻana o 25, 50 a 100 mg paha. Hiki i kaviavia ke mālama i nā haʻawina kō maʻa maʻamau ma ke ʻōpū ʻole a ma hope o ka ʻai ʻana. Ma muli o ka lawe ʻana i nā papa, ʻeha, ka ʻōpū, ka ʻōpū, ka luaʻi ʻana, hiki i ka nasopharyngitis ke hiki. Aia ka papa inoa o nā contraindications:
- maʻi maʻamau ketoacidosis,
- SD 1
- lactation
- hapai
- mau makahiki malalo mai o 18 makahiki.
Kūkulu ʻia kēia mau paila maʻi ma ka vildagliptin, e pili ana i ka hana o nā pancreas, e hoʻoikaika ana i kāna hana. Hōʻike ʻia ka lāʻau lapaʻau no ka monotherapy o nā ʻano maʻi type 2, ka mea e hoʻohui i ke ʻano kino a me ka ʻai. ʻAʻole he nui nā hapanui o nā maʻi e like me ka hoʻohewa ʻia. ʻAʻole hiki iā ʻoe ke hoʻohana iā Galvus me:
- hoʻonāukiakau nunactary
- nāwaliwali o ka puʻuwai
- a emi mai ma mua o 18 mau makahiki.
Nā ʻōwili Incretinomimetics
ʻO kekahi hui hou o nā lāʻau lapaʻau hou mai ka moʻokāki nui o ka huahelu he glucagon-like polypeptide-1 agonist receptor agonists. Hoʻokuʻu ʻia ka lāʻau lapaʻau ʻo Exenatide ma aneʻi nei, kahi i hāʻawi ʻia i ka synthesis o ka insulin. E pale i kēia kiʻi, kōkua ka lāʻau lapaʻau i ka hōʻemi ʻana i ka hana o glucagon. Hāʻawi kēia mau hopena i nā hoʻoliʻu koko koko i loko o nā palena maʻamau. Ua ʻike ʻia nā hopena maikaʻi o Exenatide i ka hui pū ʻana me ka metformin a i ʻole ka hopena sulfonylurea. Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, pono e nānā i nā contraindications i ka lāʻau lapaʻau.
- maʻi diabetes type 1
- maʻi maʻamau ketoacidosis,
- pilikia hōʻeha loa,
- makahiki i 18 makahiki
- ka mōʻaukala o ka pancreatitis.
ʻO nā lāʻau mai ke kolamu biguanide
ʻAʻole hiki ke noʻonoʻo i ka diabetes mellitus me ka ʻole o ka hoʻohana ʻana i nā biguanides, i hoʻomaka ʻia e hoʻohana i nā lāʻau lapaʻau ma mua o nā hapalua o nā kenekulia. Hoʻopaʻa ʻole paha kekahi o nā luna o kēia hui.
I kēia hihia, ʻo ka mea nui o nā biguanides hou o ka mea hoʻonaninani ʻo ka metformin hydrochloride. Ma kāna kumu, loaʻa nā lāʻau lapaʻau like ʻole he nui, hiki ke loaʻa i nā ʻokoʻa like ʻole.
ʻO kēlā lāʻau lapaʻau no ka maʻi diabetes ʻaʻole wale nō he hopena hypoglycemic wale nō, akā kōkua pū hoʻi e hōʻemi i ka paona, he mea nui ia no ka hapanui o nā maʻi maʻi me ka pathology kūʻokoʻa insulin. ʻO kekahi o nā pono o ka metformin hydrochloride ʻo ia ka hoʻohaʻahaʻa i nā pae o ka glucose koko me ka ʻole e kumu i ka hypoglycemia.
ʻO nā ʻano like ʻole o nā lāʻau biguanide ke kuhikuhi ia:
- Me ka insulin, e kōkua ana i ka hoʻemi ʻana i ka hana glucose ma o ka ʻāʻī, ʻoiai e hoʻonui ana i ka pae o ka naʻau o ka hepatocides. Eia kekahi, alakaʻi kēia hui i kahi hoʻonui i ka synty glycogen a me kahi laʻa o ka glycogenolysis.
- Hoʻolaha nā hoʻolaha i ka hoʻolaha ʻana i ka insulin.
- Hoʻohana maikaʻi i ka hoʻokuke wikiwiki ʻana o ka glucose mai ke kino.
- Hoʻopili ʻole i ka hoʻopili ʻana o ka glucose i loko o kahi pānaʻi.
- Hoʻonui i ke kaʻina o ka hoʻohanaʻana i glucose i loko o ke kino.
ʻO kahi lāʻau lapaʻau maʻi koho kūpono kūpono e pili ana i ka metformin hydrochloride ʻaʻole e hoʻohaʻahaʻa wale i ke kō koko, akā ua pale aku hoʻi i kona hoʻonui i ka wā e hiki mai ana. Eia kekahi, hoʻohaʻahaʻa iki nā biguanides i ka hapa nui o nā poʻe maʻi a ʻaʻole i loaʻa kahi helu o nā contraindications a me nā hopena ʻino.
Pono e hoʻomanaʻo ʻia he puka hou o nā lāʻau lapaʻau no ka maʻi maʻi, e emi mālie i ka hoʻohana ʻana o nā biguanides.
Ma ka manawa like, hiki i nā papa Metformin ke hōʻoluʻolu i ke ala o ka maʻi i kūʻē i ka maʻi diabetes a ʻo nā huahana pono loa nā huahana no nā maʻi o nā maʻi.
Hiki paha ke pale i ka hiki ʻana o ka maʻi?
Aia kekahi mau hui pilikia no ka poʻe i hiki i lilo i mau mea i hoʻokō i ka hoʻomohala ʻana i ka maʻi diabetes.
Hoʻopili kēia mau mea, ʻo ka mea mua, ʻo ka wahine a me nā kāne ka poʻe i loaʻa i ka predisposition hoʻoilina i ka hoʻomohala ʻana i ka maʻi, nā poʻe luhi, nā poʻe me ka atherosclerosis o nā moku a i ʻole hypertension, nā wahine, inā i ka wā hāpai ʻia he hōʻike kahi maʻi maʻi gestational a i ʻole ke ahonui i ka ʻole. papakā, nā wāhine i hala i mua he kolohe.
ʻO nā ʻōlelo koʻikoʻi e kōkua i ka pale ʻana i ka hoʻomohala ʻana o ka maʻi penei:
- Ke hoʻomau nei i nā loiloi mau i ka pae o ka glucose koko.
- E hoʻomaʻamaʻa piha i kāu meaʻai, e pale i ka ʻai a me ka wikiwiki. Pono ka papa ʻai i ka hōʻaiho piha ʻana i ka meaʻai momona a me nā kō, nā huahana bakery, nā mea momona a me nā meaʻai. ʻO nā huahana maikaʻi i hōʻoia ʻia e like me ka kāpeti, celery, spinach, cereals (koe wale nō ka laiki a me ka semolina), nā legumes. ʻO ka papa ʻaina meaʻai no ke kō hānai kiʻekiʻe e hoʻomohala ʻia e ka mea lapaʻau e nānā i nā ʻano pono āpau o ka mea maʻi.
- E hōʻole i ka hana ʻino, mai hōʻino i ka waiʻona a me ka ulaula
- E alakaʻi i kahi ʻano hana ikaika, pāʻani i nā haʻuki. Pono pono ka hoʻomaʻamaʻa e hoʻoponopono i ke kō koko. ʻO kekahi manawa lawa ka mea komo wale i nā lā hele i kēlā me kēia wahi a ma nā ʻano like ʻole o kou ola maʻamau. ʻO kahi wahi kūpono no kēlā "hāmeʻa" e lilo i ka nahele a i ʻole ka paka. Hiki iā ʻoe ke hana i kahi hoʻonohonoho o ka home ma ke keʻena paha. I kēia hihia, mea nui e noʻonoʻo i nā pono a me nā hiʻohiʻona o kou kino a ʻaʻole hoʻi e kau palena.
- E hōʻalo i nā kūlana hoʻokaumaha, hāʻawi i kahi hoʻomaha maikaʻi a hoʻokipa maikaʻi i kekahi pilikia.
Inā aia kekahi mau mea e hoʻopilikia ai, e pono e nīnau aku i ke kauka a hōʻoia i kāu kō koko. Hoʻopilikia ka maʻi huakaʻi ma nā maʻi ʻelua ʻelua - ke koko a me ka urine.
I mea e hoʻoholo ai i ka pae o ka glucose, pono e lawe ʻia ke koko i ke kakahiaka ma kahi ʻōpū ʻole.I kēia hihia, ʻo ka ʻai hope loa ma kahi o nā hola he ʻumi ma mua o ka lawe ʻana. ʻO ka hoʻomākaukau kūpono wale nō ke kōkua i ka loaʻa ʻana o ka ʻike pono. Inā hōʻike nā hopena o nā hōʻike i kahi maʻi hiki, hiki ke hoʻouna ʻia i ka mea maʻi no kahi nānā ultrasound o ka pancreas. Hoʻomau ʻia ka maʻi a me ka mālama ʻana i nā patology e ka endocrinologist.
ʻO ka wikiō ma kēia ʻatikala e kikoʻī ai ka lāʻau lapaʻau maʻi maikaʻi loa.
He aha ka mea ʻokoʻa ma waena o T1DM a me T2DM
ʻO ka ʻokoʻa ma waena o ka maʻi diabetes type 1 a me ke ʻano type type 2 he nui loa. Ma ka hihia mua, aia ka emi ʻana o ka hoʻokahe ʻia o ka hōʻemi o ka hormone o ka pancreas (insulin), ma muli o ia glucose, kahi e komo ai i ke kino me ka meaʻai, ʻaʻole i wawahi a hoʻonoho wale i loko o ke koko.
E hoʻihoʻi hou i ka hana maoli o ka insulin i kēia manawa, ʻaʻole hiki i nā lāʻau lapaʻau hou. No laila, ʻae ʻia ka mea maʻamau i ka maʻi maʻi i ka hoʻōla ʻana.
A me T2DM, hoʻāla ʻia ka insulin i loko o ke kino ma ka nui o ka maʻamau, akā i ka manawa like i hiki ke lele i ka hoʻopili ʻana me kāna mau ʻoihana, kahi e hoʻōki ai i ka haʻahaʻa glucose i lawa ʻole. ʻO ia, i kēia hihia ke loaʻa nā makana hou. ʻO ka mea nui ka lawe maʻamau mau i nā lāʻau lapaʻau no ka maʻi type type 2 i kuhikuhi ʻia e kāu kauka a pili pono i kahi lāʻau lapaʻau.
I ka pilikia ʻana i ka hoʻomohala ʻana o ka T2DM he mau kanaka ia:
- e alakaʻi ana i kahi nohinohi,
- ʻokiʻoki
- aole e nana ana i ko lakou ai, ka ai i ka ai a me ka ai i ole, a me ka eʻe mau ana i ka pō,
- e loaʻa ana i nā maʻi ʻeha, me ka hoʻohui pū ʻana o ka ʻōnaehana genitourinary,
- kahi i ʻike pinepine ai ka dehydration o ke kino, etc.
Pono ka poʻe e pilikia i ka ulu ʻana i ka maʻi diabetes type 2 no ka ʻike maʻamau i ka pae koko koko. A inā i kahi hoʻonui o kona ʻōnaehana, hoʻomaka koke e lawe i nā lāʻau lapaʻau i ʻae ʻole i ka maʻi e ulu hou.
ʻO nā ʻano maʻi maʻi
Aia he ʻano ʻelua maʻi. Hōʻike ʻia lāua ʻelua i ke koko koko kiʻekiʻe, e loaʻa ana no nā kumu like ʻole. Me ka maʻi maʻamau 1, ka mea i kapa ʻia hoʻi i ka insulin-hilinaʻi, ke kū ʻole ʻole ke kino i kēia hormone nui. ʻO kēia no ka luku ʻia o nā cell pancreatic. Aʻo ka lāʻau nui loa no kēia ʻano maʻi maʻi maʻi is insulin.
Inā ʻaʻole nele nā hana a nā pancreas, akā no kekahi mau kumu e hōʻemi ai i ka hormone liʻiliʻi, ʻaʻole i ʻole nā cell o ke kino e lawe, e hoʻomohala i ka maʻi diabetes type 2. Ua kapa ʻia hoʻi he kūʻokoʻa kūmole insulin.
I kēia hihia, hiki ke piʻi aʻe ka pae o ka glucose ma muli o ka hoʻokomo nui o nā huapalapala, nā pilikia hōʻino. ʻO ka manawa pinepine, me ke ʻano maʻamau o ka maʻi maʻamau, he nui ke kaumaha o kekahi kanaka.
No laila, ua ʻōlelo ʻia e kaupalena i ka ʻai ʻana o ka ʻai o ka mea kalapu, ʻoi aku nā huahana palaoa, nā ʻeke a me ke kō. Akā, ma kahi o kaʻai, he mea nui ka lāʻau lapaʻau.
Aia i nā ʻano like like ʻole no ke ʻano maʻi like ʻole 2, ua kuhikuhi ʻia e ke kauka ma muli o ka ʻano o nā ʻano like o ka maʻi.
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ʻO ke koho o ka lāʻau lapaʻau
Ma hope o ka hoʻomohala ʻana o ka maʻi diabetes 2 ʻano, ua hoʻoholo ke kauka i ka papa o ka mālama ʻana i ka mea maʻi. ʻO ka mea mua e hoʻolohe i ka nānā ʻana i ka meaʻai a me ka paʻakikī o nā hana pilikino liʻiliʻi. ʻO kēia ala kūpono i ka mālama mua ʻana o ka mea maʻi maʻi e kōkua iā ia e hōʻoluʻolu hou a hiki i kekahi mau manawa ke hoʻomaʻamaʻa i kāna pae gula.
Ma ka hoʻomaʻamaʻa lāʻau lapaʻau, ʻaʻole i kuhikuhi koke ʻia nā papa papa no ka maʻi type 2 i ka poʻe kahiko. Ma lawa ka hoʻokō pololei ʻana i nā ʻōlelo a pau o ka endocrinologist e pili ana i nā meaʻai a me nā ukana hāmeʻa. Pono ka mea maʻi e hoʻomau mau i ka pae o ka kō. Kēia mau mākaʻikaʻi mau e kōkua i ka hoʻokumu ʻana pehea e hana ai ka papa ʻaina i ʻōlelo ʻia.
Inā, e like me ke ʻano o ka hōʻike o ka glucometer, ʻaʻole hiki i ka mea maʻi ke hoʻokō i kahi hopena maikaʻi ma ka hoʻohaʻahaʻa ʻana i ke kōpaʻa ma o kaʻai ʻana a me ke ʻano hoʻoikaika ʻana, a laila ua hoʻoholo ka endocrinologist no ka hoʻopuka ʻana i nā lāʻau.
He mea nui loa e koho ai ke kauka i ka lāʻau lapaʻau. ʻOiai ke kūlike nei ka manaʻo o nā lāʻau āpau, eia kekahi kaʻokoʻa ma kā lākou hopena. Ke koho nei i kahi lāʻau mālama, ke kau nei ke kauka ʻaʻole ma luna o kāna hana wale nō, akā ma ke ʻano o ka mea maʻi, kona momona, nā hōʻailona ʻona o ka maʻi, nā hōʻailona alima, ka hala mau ala e pili ana i nā kānaka kahiko.
Hoʻoholo wale ʻia ka Dosage ma ka kumu o nā hōʻike lab. No ka laʻana, ʻo ka mea maʻi me ka momona nui e kuhikuhi ʻia i ka lāʻau Metformin i nā liʻiliʻi liʻiliʻi. A no nā maʻi maʻi 'ano me kahi index index mass normal kino, ua koho ʻia nā papa e hoʻoikaika i ka hoonui o ka hormone (insulin).
ʻO ka maʻi diabetes mellitus type 1 a me 2 e pili ana i nā maʻi metabolic, no laila ʻo ka hopena o nā lāʻau lapaʻau, ʻo ka mea mua loa, pono ke kuhikuhi i ka lawe ʻana i nā kaʻina o ka metabolic i ke ʻano maʻamau.
Ma muli o ke kumu o ka maʻi diabetes type 1 ka make o nā cell beta e hoʻoili i ka insulin, pono e lawelawe ʻia kēia ʻoliva mai waho. Hiki ke mālama ʻia ka kahe ʻana o ka insulin i loko o ke kino a i ka hōʻemi ʻia ʻana a i ʻole e loaʻa i kahi mākena insulin. Me nā maʻi diabetes e hilinaʻi nei i ka lolo, ʻaʻole naʻe, ʻaʻohe ala ʻē aʻe o ka mālama ʻana i ka insulin.
No ka mālamaʻana i ka maʻi diabetes type 2, kuhikuhi nā kauka i nā ʻano lāʻau like ʻole e kōkua i ke kahe koko. ʻAʻohe pono e lawe i ka insulin i kēia pūʻulu o nā maʻi maʻi.
ʻO kaʻoiaʻiʻo, aia ke kauka wale nō ke kuleana e kākau i kahi lāʻau lapaʻau no nā maʻi maʻi type 2. A pono e hana ʻoe i kēia ma hope o ka hoʻokolokolo piha.
ʻO nā peni āpau i lawe ʻia e nā mea maʻi me nā ʻano maʻi mell type type 2 i hoʻokaʻawale ʻia i kekahi mau ʻāpana.
Sulfonylurea. ʻO kēia lāʻau lapaʻau e hōʻemi i nā kiʻekiʻe o ke kō me ka hoʻoulu ʻana i ka pancreas, kahi, ma lalo o kona mana, e hoʻomaka ana e hoʻoikaika ikaika i ka insulin. Aia kekahi mau lāʻau lapaʻau i ka hanauna mua a me ka lua. ʻO ka hapa mua:
Akā i kēia manawa, kokoke pau kēia mau lāʻau lapaʻau. Hoʻomaopopo pinepine nā kauka i nā hanauna hou o nā lāʻau, ʻo ia kēia:
- Makukula,
- Hanohano XL,
- DiaBeta,
- Nā ʻaumona
- Kahalena PresTab,
- Amaryl.
Biguanides. Kōkua kēia lāʻau lapaʻau i mea e hiki ai i ka insulin ke hoʻoponopono i ka nui o ke kōo hilo i loko o nā hale.
Nui ka ʻike i nā pona o nā ʻiʻo. Eia kekahi, ʻo ka lawe ʻana i kēia mau paila e hiki ke pale i ka hoʻokuʻu o ke kō ma ka ate.
ʻAʻole hiki i kēia mau lāʻau ke hana no ka poʻe i loaʻa nā hoʻopiʻi i ka palā a i ka naʻau. Inā ʻaʻole, hiki paha kahi hanana lactic acidosis.
Kēia pū me kēia hui nā hua lāʻau hou e like me:
- Biguanides
- Hoʻolaha
- Riet,
- Hoike XR,
- Glumetza,
- Fortamet
Thiazolidinediones. Kōkua kēia mau paila i ka hōʻemi ʻana i ka kūʻē o ka insulin.
Hoʻopilikia lākou i nā kikoʻī a me nā pili adipose. Aia he mau lāʻau lapaʻau ma kēia hui, ʻo ia ʻo Actos a me Avandia.
He ʻōiwi hou kekahi i nā lāʻau lapaʻau. Akā, pono ʻoe e lawe iā lākou me ka makaʻala nui.
Holo i ke kō o ke koko nā wai he 1-2 mau pule ma hope o ka hoʻomaka ʻana o ka lawe ʻana i kēia mau lāʻau. I ka manawa like, loaʻa iā Avandia ka hopena maikaʻi loa ma ka hana o ke ʻōnaehana cardiovascular.
No laila, no ka poʻe pakeke, ʻaʻole i ʻōlelo ʻia ka koho ʻana o ka poʻe hope.
ʻO kaʻoiaʻiʻo, aia ke koho o kahi lāʻau lapaʻau ma luna o nā mea he nui. A ua noho mau ka hoʻoholo hope loa me ke kauka kauka.
Tolinase - ka lāʻau lapaʻau no ka mālama ʻana i ka maʻi koko, e pili ana i ka huaʻala o ka huaʻawa o ka huahelu sulfonylurea. Hōʻike ʻia wale nō i nā hihia ʻaʻole i haʻi ka mea maʻi i nā hoʻopiʻi o kahi ʻano vascular.
ʻOiai ka hopena o ka "hou", ʻaʻole i kuhikuhi mau ʻia ka mea hana no ka hoʻohana mau ʻana. ʻO kaʻoiaʻiʻo inā ʻoe e lawe i ka lāʻau lapaʻau no ka manawa lōʻihi, a laila lilo ke kino i "hoʻohana ʻia" me ia, a hoʻemi nui ʻia ka hopena o ka lāʻau.
Ua kaukau ʻia ka nui o ka lāʻau i ke kū hoʻokahi, me ka mālama ʻana i nā ʻōmole glucose ma kahi ʻōpū ʻole, a me ke kō ma ke kanaka ma hope o ke kaumaha gula.
- No nā mea hoʻomaka, hiki iā lākou ke kau i ka papa hoʻokahi i kēlā me kēia lā.
- I ka lōʻihi o ka manawa, pono ʻoe e hoʻonui i ka dosage i ka mea māmā, a ua hoʻoholo ʻia ma muli o ka dinamika o ke kō.
- Lawe i nā manawa he i ka lā.
- Inā hana ʻia ka lāʻau lapaʻau i ka manawa like, ua ʻoki ʻia ka nui o ka lāʻau lapaʻau.
He hopena palupalu la ka lāʻau lapaʻau, hiki ke hoʻonāukiuki i ka hōʻeha ʻana o ka maʻi a me ka luaʻi. Me ka hoʻomaloka ʻole i ka lāʻau a i ʻole nā mea i hoʻohui ʻia, ʻike ʻia kahi hana kūlohelohe me nā ʻike kino.
Līpī loa ʻo ia i ka lawe ʻana i ka wā e lawe ai i ka pēpē a me ka hoʻoloki keiki i ka pēpē. Contraindications pili: maʻi pāpaʻi a me ka hana maʻamau.
ʻO ka mea hana o ka lāʻau lapaʻau, ʻo ʻAmelika Hui Pū ʻIa, hoʻomaka ke kumukūʻai mai 1500 rubles a ma luna.
I ka maʻi mellitus o ka lua a me ke kolu o ke ʻano, ua kauoha ʻia nā lāʻau lapaʻau kūikawā e hōʻemi i ke kō koko.
Na lāʻau lapaʻau hou
Hiki i ka poʻe maʻi e hōʻeha ana i ka maʻi diabetes type 2 ke hele me nā wai ʻole e hoʻohiolo i ke kō. Mālama lākou i nā pae o ka glucose i loko o nā palena maʻamau ma muli o ka nui o ka hana pilikino a me ka ʻai me ka liʻiliʻi o nā mea kākena.
I nā maʻi he nui, ua emi nā keʻena o ke kino, no laila pono ʻoe e hoʻololi e lawe i nā lāʻau lapaʻau. Ua kau ʻia lākou i ka wā, ʻoiai me ka mea ʻai, hoʻomau ʻia ke kōpaʻa no 3 mau mahina.
Hoʻoholo ʻia nā ʻano kūpono o ka mālama ʻia e pili ana i nā ʻano pilikino o kēlā me kēia maʻi, i ka nānā ʻana i nā kikoʻī āpau.
ʻO ka pahuhopu o ka lapaʻau e hoʻihoʻi i ka pancreas, hoʻōla i nā kaʻina metabola a hoʻemi i ka pane ʻana mai o ka nui o nā ʻōnaehana o ke kino o ka insulin. No ka hapanui o nā maʻi, ʻo ka pauna i ka lāʻau diabetes i ka metformin e hoʻohālikelike ʻia.
Hoʻonohonoho maikaʻi ia i nā kiʻekiʻe o ke kō, hāʻawi i ka hoʻohaʻahaʻa ʻana a he ʻemi iki ka hopena. Hiki ke hoʻokaʻawale ʻia nā ʻina āpau o ka mālama ʻana i ka maʻi diabetes 2 e holomua:
- ka mea mua, he meaʻai meaʻai,
- ʻo ka lua ua Metformin i hui pū me nā meaʻai,
- ʻo ke kolu ʻo Metformin i loko o ka mālama paʻakikī me ka hoʻohana ʻana i ka meaʻai a me ka hoʻomaʻamaʻa ʻana,
- ka ha he kīʻaha i ka hui pū ʻana me ka hoʻomaʻamaʻa ʻana a me ka mālama ʻana i nā lāʻau lapaʻau paʻakikī.
Kuhihewa ʻia kēia mau papa he mau mea huna. Ua hoʻohana ʻia nā derfatives o Sulfonylurea mai 1955. I kēia mau lā, aia kēia mau lāʻau i ʻekolu mau hana o ka hana:
- hoonui i ka huna huna e nā kanaka pancreatic,
- ho'ēmi i kā lākou hana momona glucagon,
- hoʻonui i ka pilina o nā mea pale aku o ka ʻenekini kūpono no ka insulin.
Ke hōʻike nei no kā lākou hoʻohana ʻana nā non-insulin-depend-diabetes mellitus (NIDDM), kahi e lawe ʻole ai ka meaʻai a me ka hoʻoponopono regimen i kekahi hopena maikaʻi. He mea kūpono ia e ʻike ai i ka nui o nā derivatives o sulfonylurea e hoʻonui i ka hopena o ka hypoglycemia a kōkua i ka loaʻa kālā. Eia kekahi, loaʻa iā lākou kekahi mau hopena maikaʻi ʻole:
- nā pepeke
- wahawa
- leo koma
- hepatotoxic mau hopena
- kue
- blockade nā pā o potassium me ka myocardium.
ʻO kēia lāʻau hypoglycemic mai ka lua o ka hui sulfonylurea kūloko i hoʻohana maikaʻi i ka hana mua o ka hana hana insulin. ʻO ka mea hoʻohana i ka gliclazide. Hoʻemi ia i ka manawa mai ka ʻai ʻana i ka hoʻouka insulin. ʻO ka hopena, ala ka manaʻo o ka hormone ma mua o ka pāʻina a i ʻole ka momona ukana. Eia kekahi, ʻo ka lāʻau lapaʻau he mau hana penei:
- hemovascular
- antioxidant
- moʻoʻala.
Paʻi ʻia ka maʻi Diabeton e hoʻemi i ka pae o ka kolamu ma ke koko a me ka palupalu i ka pāʻai, paipai i ke kahe koko i loko o nā kīʻaha liʻiliʻi. ʻO nā hiʻohiʻona nui o ka lāʻau lapaʻau:
- Nā hōʻailona no ka hoʻohana ʻana. Kāhea 2 diabetes mellitus i ka hala ʻole o ka hopena o ke kaupaona ʻana.
- Nā hopena hopena. i ka pale hewa ʻana o ka reimen dosing, ka pōloli, ka ʻeha, ka ʻōpū, ka aphasia, ka mea hoʻopaʻapaʻa, ka hopohopo, a me ka insomnia ka mea.
- Nā Hoʻohui Hoʻohui lākou i ka ketoacidosis, nā hōʻeha a me nā ʻinoʻino paha, coma, precoma diabetes, ʻo ka hānau ʻana, ka maʻi diabetes type 1.
Hoʻokomo ʻia ka lāʻau lapaʻau e pili ana i ka glimepiride, kahi mea e hoʻohaʻahaʻa i ke kao o ka glucose i loko o ke koko. ʻO ka hana o ka hana ke hoʻokuʻu i ka insulin mai nā cell beta pancreatic.
ʻO kahi hopena, e hoʻomaikaʻi ka paneʻana o ka glucose. Hōʻike ka hoʻohanaʻana o Amaril i ka maʻi diabetes type 2.
Hiki nō ke hoʻohana pū i ka hana hui me ka metformin a i ʻole insulin. ʻO nā hoʻohālikelike no ka hoʻohana ʻana:
- huakini a me ka hana lima,
- nā makahiki o nā keiki
- hoʻoweliweli a ʻokoʻa ʻole i ka lāʻau lapaʻau,
- ʻAno maʻi type 1
- hapai, lactation,
- precoma, coma, diabetes ketoacidosis,
- ka predisposition hoʻoilina i nā maʻi ʻeha.
Hiki i nā hana amaril ke hoʻopili pū me nā hopena kūpono ʻole e pili i ka aneane o nā ʻuhane āpau. ʻO nā hopena nui, ka:
- ninini
- utuka
- mea momona
- manaʻo ʻino
- lie kanikela
- pololi
- hilahila.
ʻO ka lāʻau ikaika loa e pili ana i ka glibenclamide, ka mea e hoʻoikaika i ka hana o ka insulin a hoʻonui i ka hopena-hoʻokuʻu i ka insulin. Ma muli o kēia, ua manaʻo ʻia ka lāʻau lapaʻau e ʻeha. Eia kekahi, ʻo kēia mau maʻi maʻi diabetes i kahi hopena cardioprotective a me nā hopena antiarrhythmic. ʻO nā nuances koʻikoʻi āu e pono ai e ʻike i ka wā e lawe ai i kēia lāʻau lapaʻau.
- Nā hopena hopena. ʻO nā ʻano maʻi, ka loaʻa ʻana o ka paona, ka maʻi, ka cholestasis, arthralgia, nā maʻi neurological.
- Nā Hoʻohui Hoʻokomo lākou i ka comos hyperosmolar, ketoacidosis, coma, coma, type 1 diabetes, ʻoki kuni, hōʻeha, hōʻeha, leukopenia.
ʻO kahi hiʻohiʻona o kēia lāʻau lapaʻau he kina hepatic. Ma kahi kokoke o 95% o ka lāʻau lapaʻau i lawe ʻia ma loko o ka bile. No kēia kumu, ʻaʻole pono ka hoʻoponopono ʻana o ka maʻi maʻi i nā mea maʻi me nā maʻi o ka maʻi. Hoʻomaopopo ʻia ka lāʻau lapaʻau no nā mea nona ka hana a me ke kino e hiki ke hoʻoponopono i ka pae glucose. Ma mua o ka hoʻohana ʻia, pono e aʻo ʻia i nā ʻano koʻikoʻi o Glycvidon:
- Nā hopena hopena. i nā hanana pinepine, hypoglycemia, allergies, dyspepsia, ua hoʻomaopopo ʻia nā loli i loko o ke ʻano o ke koko.
- Nā Hoʻohui Hoʻopili kēia ma ka lolo 1, ka maʻi maʻi kipa, ka hapai, ka lactation, ka manawa ma mua o ka hōʻemi, ka acidosis, precoma.