Nā papa acekardol - nā mea kikoʻī a me nā mea hōʻike, ka hana a me nā contraindications, nā analogues a me nā kumukūʻai

ʻO ka lāʻau "Acecardol" kahi acetylsalicylic acid, pani ʻia, e hoʻokaʻawale pololei i loko o nā wahi o hope. He lāʻau lapaʻau ia non-steroidal me ka hopena anti-inflammatory. Hoʻokomo ʻia ka Acetylsalicylic acid i loko o nā pāʻina like ʻole i nā mea hou acecardol.

Loaʻa iā ia ke pale i ka synthesis o ka thromboxane a hoʻopaʻa i ke kaʻina o ka hoʻohui ʻana i nā platelets i nā clots. Hoʻomaopopo ʻia kēia hopena o Acecardol me nā liʻiliʻi liʻiliʻi o kona hoʻohana a hoʻomau me ka hoʻohana hoʻokahi no ka hebedoma. I nā dosis kiʻekiʻe, he lāʻau antipyretic, analgesic a me anti-inflammatory ka hopena.

ʻO ka papa 1 i ka 50, 100 a i ʻole 300 mg o ka acid acid acetylsalicylic acid. No ka lāʻau lapaʻau e pili ana i ka lāʻau lapaʻau a me ka ʻoihana lapaʻau o nā NSAIDs, a me ka hoʻohui antiplatelet.

ʻO ke kumu o ka hana o ka hana o ka hiki o ke kaohi ʻana o ka cyclooxygenase e ka neʻe ikaika, ka mea i hōʻemi ai i ka hoʻoulu ʻana o ka thromboxane A2 a me kahi hoʻohaʻahaʻa i ka platelet aggregation. Loaʻa ka hopena antiplatelet e ka lawe ʻana i hoʻokahi papa i hoʻokahi pule.

Nā kuʻuna no ka hoʻohana ʻana iā Acecardol

Kāohi ʻo Acecardol i ka trombosis, pale i ka hoʻomohala ʻana a me ka holomua ʻana o ka hōʻeha ʻana o ka naʻau, nā puʻuwai ischemic, a me ka thromboembolism. Hoʻohana lōʻihi ka hoʻohana ʻana i ka acecardol i ka lōʻihi a me ka maikaʻi o ke ola o nā maʻi. ʻO nā mea maʻi i hopohopo ʻia e ka puʻuwai wikiwiki i hōʻeha ʻia i ka hoʻomaikaʻi ʻana i ko lākou kūlana, ka maikaʻi o ka lehulehu a me ka maʻamau o ke kaumaha.

Ua ʻōkuhi ʻia ka Acecardol no ka pectoris angststable ka lōʻihi, i mea e pale ai i ka infocrose myocardial recurrent, e pale ai i ka embolism pulmonary (me kāna mau lālā) a me ka thrombosis vein hohonu (me ka lōʻihi o ka immobility, no ka laʻana, i ka wā lōʻihi).

Nā ʻōkuhi no ka hoʻohana ʻana i ka dosis Acecardol

E kamaʻilio me kāu kauka e pili ana i ka maʻi maikaʻi loa i kēlā me kēia lā. Hoʻomoe nā Acetylsalicylic acid i kahi 50-150 mg i kēlā me kēia lā no ka hoʻohana lōʻihi. Ma ke ʻano he kānāwai, ua kuhikuhi ʻia lākou no ke ola inā ʻaʻohe nā hopena koʻikoʻi.

Aia ka mahele maʻi o nā lāʻau lapaʻau i hoʻohana ʻia i ka pale ʻana o nā maʻi like ʻole. I mea e pale ai i ka infarction myocardial akahola, me ka ʻole a me ke alo ʻana o nā mea pōpilikia, thromboembolism o ka pulmonary artery a me kāna mau lālā, ua hoʻonoho ʻia ka veins thrombosis 100 mg i kēlā me kēia lā a i ʻole 300 mg i kēlā me kēia lā maʻa (ʻoi aku ka ʻōlelo ʻana e hoʻopiʻi i ka papa mua no ka hoʻomau koke ʻana).

Nā hiʻohiʻona noi

ʻOiai e lawe ana i ka lāʻau lapaʻau Acekardol, pono e hoʻomaʻamaʻa i ka wā o ke kaʻa ʻana i nā kaʻa, nā hana hoʻokūkū a i ka wā e hana ana i nā hana ʻē aʻe e pōʻino ana i koi ʻia ka nui o ka nānā ʻana a me ka wikiwiki o ka hopena psychomotor.

I ka wā mālama me ka hoʻomākaukau ʻana e pili ana i ka acetylsalicylic acid, pono e hoʻokaʻawale ʻia nā hōʻike koko, ʻoiai ua hāʻawi kēia mea waiwai i kona ʻoki koʻikoʻi. Me ka hoʻohana mau ʻole ʻole a kaohi ʻole o ka acecardol, nui ka maikaʻi o ka ulu ʻana o ke kaila i loko.

Ke lawe like ʻia me ka waiʻona, hoʻonui ʻia ka hopena o ka ʻalā, piʻi ka nui o ke koko a hoʻonui ʻia ko lākou manawa, a hoʻonui ʻia ko lākou manawa, a me ke ʻano o ka hōʻino ʻana o ka membrane mucous o ka gastrointestinal tract e hoʻonui.

ʻO Acecardol potentiates ka hopena o nā lāʻau lapaʻau e like me:

- pākana,
- heparin,
- insulin
- nā maʻi glycosides.

Acekardol - he aha kēia mau peni mai

Kuhi nā kauka i nā papa Acekardol no ka pale ʻana i ka maʻi pale, ma hope o ka hōʻeha ʻana i ka puʻuwai a me nā kīʻaha koko a i ʻole e pale ai i kahi pilikia o ka hōʻea ma kahi lua i nā maʻi nā mea i loaʻa iā ia. ʻO ka hōʻeha o ka hōʻeha a me nā ʻeha ma ka umauma (angina pectoris) lawelawe pū kekahi i ke kumu e hoʻomaka ai ka lawe ʻana iā Acecardol ma ke ʻano he nui i loko o ka hoʻoulu ʻia ʻana o ka hōʻeha kaumaha.

Wahi a nā ʻōlelo kuhikuhi no ka hoʻohana ʻana, aia ʻo Acekardol i ka hui o nā lāʻau antiplatelet. Hoʻokomo ʻia kāna hana i ka pale ʻana i ka clumping (ka ʻōpū) o nā platelets a me nā ʻāpana koko ʻula. ʻO ka hopena o ka lāʻau Acekardol ma ke kaʻina o ka hematopoiesis e hōʻoluʻolu i ka hoʻomohu o nā capillaries, ka hoʻomoʻa ʻana i nā palaka koko, i hana ʻia ma muli o nā hanana pathological e kū mai ana i ka puʻuwai a me nā kīʻaha koko.

ʻO ka mea hana e hoʻohālikelike ai i ke kumu o ka hoʻohālikelike o ka lāʻau Acecardol ka acetylsalicylic acid, i ʻike ʻia i kona ʻano ākea o nā hopena therapeutic. Hoʻohana ʻia kēia mau mea e like me nā mea kōkua ma kahi o ka pākeleka pakeneka.

• polyvinylpyrrolidone haʻahaʻa loa - 1,8%,
• ʻōpio palaoa - 9,5%,
• microcrystalline pauma o ka lāʻau polysaccharide (cellulose) - 5.6%,
• Lāwalu Lāwī (or magnesium stearate) - 0.6%,
• talc - 1,7%
• waiū glucose monohala (lactose) - 53%.

E hoʻokuʻu i ke ʻano

ʻO ke kūlana o ka lāʻau Acecardol, kahi hōʻike i hoʻākāka ʻia nā waiwai o ke ʻano lāʻau, he papa i uhi ʻia me ka ʻālehu keʻokeʻo a me ke ʻano o nā mea ikaika o 50, 100 a i 300 mg. Hōʻailona ka mea a ia i hana ai i ka waiwai o ka gastric-soluble i ka cachet (ʻoiʻi ka lāʻau).

• cellulose acetate - pale i ka haʻalele i ka esophagus,
• ka titanium dioxide - e pani nei i ka hopena o ka waikawa hydrochloric,
• aila castor (ricinoleic acid) - hoʻomaʻemaʻe a hoʻomālamalama i ke ʻano o nā papa ma ka esophagus.

Pharmacodynamics a me ka pharmacokinetics

ʻO ka hana o ka hana a ka luna anti antiplatelet Acekardol, e like me ke kuhikuhi i ka hoʻohana ʻana, kau ʻia i ke kāohi ʻana i ka loaʻa o nā thromboxanes i ka māhele palapala o ka cyclooxygenase. Hāʻawi ke kaʻina hana pale e kāpae i ka hoʻopili ʻana o ka prostanoids a me ke kīpē ʻana i ka platelet aggregation, ma muli o ka hopena o ka antipyretic, hōʻemi i ka hōʻeha a me ka hoʻopauʻana i nā hōʻailona maʻi.

ʻO ka lāʻau Acecardol, ke komo ʻana i ka ʻōpū ma hope o ka hoʻopale ʻana i ka waha, ua nalowale i kona membrane-pale pale, a ke hoʻokuʻu ʻia nei ka acetylsalicylic acid e komo pono i loko o ka ʻaoʻao o ka pūpū liʻiliʻi. ʻEkolu mau hola ma hope o ka lawe ʻana iā Acecardol, ua hiki i ka piʻi nui ʻana o nā mea i loko o ke koko koko. ʻO ka mea hana o ka lāʻau e loaʻa ana e ka hilo huna renal (60% i loko o ke ʻano o nā loli, 40% ma ke ʻano o nā metabolites).

Acekardol - hōʻailona mau no ka hoʻohana ʻana

Hoʻomaopopo ʻia nā lāʻau Antiplatelet no ka pale ʻana o nā hana koko a no ka mālama ʻana i nā pilikia kaʻe. ʻO ka Acecardol, e like me ke kauoha, ua hōʻike ʻia no ka hoʻohana ʻana e pale i ka hoʻomohala ʻana o kēia mau ala:

• postomboative thromboembolism (ma hope o ka shunting, ka angllasty arterial),
• ka hōʻike o ka maʻi ʻeha o ka coronary (ʻo ka hōʻailona nui ka kaina ʻaʻole i paʻa)
• māhā
• myocardial infarction (inā aia nā mea e hoʻopuka ai e like me ka maʻi mellitus maʻi, ʻokiʻoki, ʻelemakule, etc.)
• koko i loko o nā pua hohonu.

Nā Hoʻohui

Ma muli o ka hiki ʻana o ka waika acetylsalicylic ulcerogenic i ka hoʻopili ʻana o Acecardol, ua hoʻohana ʻia ka hoʻohana ʻana i kēia lāʻau i nā keiki i lalo o ka 18 mau makahiki a ma kēlā mau maʻi e loaʻa nei nā maʻi i hoʻopaʻa ʻia ma ka mōʻaukala o ka maʻi.

• keiki puʻuwai a pale ʻole paha,
• māhuahua
• ka huhū ʻana ma ka ana o ka ʻōpū o ka gastrointestinal,
• Hoʻokomo ʻia ka palaka bronchial me ka polyposis nasal,
• erosi e hana ino ai i ka gastosa mukosa.

ʻLoe a me ke kākele

ʻO nā ʻōlelo e hoʻohana ai he kikoʻī kikoʻī loa no ka lawe ʻana i ka papa pākaukau o Acecardol. Hoʻokuʻu ʻia ka dosage i hōʻike ʻia a hoʻololi i ke ʻano o ka hoʻohana ʻana i ka lāʻau lapaʻau ʻaʻole ʻia ka ʻae ʻole o ke kauka. Pono ka lāʻau lapaʻau i loko o ka ʻōpū me ka ʻole e hōʻino i ke kūmole o ka membrane; no kēia, pono ia e luku ʻia a holoi ʻia me ka nui o ka wai. Pono ka Acecardol e lawe ʻia ma mua o ka papaʻaina. I mea e pale ai i nā hopena maikaʻiʻole ma ka mucosa, hiki ke holoi ʻia nā papa me ka wai mineral alkaline.

Ke lawe ʻo Acecardol no ka pale ʻana i nā maʻi, pono e ukali nā ʻōlelo aʻe:

Nā hopena ʻaoʻao a me nā contraindications Acekardol

Wahi a nā loiloi a me ka annotations kūlana, Acecardol hiki i nā hopena like ʻole.

• Mai ka pūnaehana ʻana: ka nausea, ka ʻōpio, ka luaʻi ʻana, ka ʻeha o ka epigastric, nā ʻōpū o ka membula mukous o ka ʻōpū a me ka duodenum, nā ʻōpio i hoʻouluhua o ka ʻōpū a me ka duodenum, ka huhui gastrointestinal, ka maʻi o ke kanalike me ka nui o ka hana o nā transaminases hepatic.
• Mai ka pūnaehana hemopoietic: ke hui pū ʻia ʻana o ASA me ka nui o ka neʻe ʻana o ka nahu ma muli o ka hopena o ka ʻalake o ASA ma ka platelet aggregation, anemia.
• He maʻi kūloko: ka hāwaha o ka ʻili, kaʻeha, ka urticaria, ka edema o Quincke, rhinitis, ka huehue o ka mucosa nasal, cardiorespiratory syndrome syndrome, a me nā hopena koʻikoʻi, e komo me ka pīhoihoi anaphylactic.
• Mai ka papa hana hanu: bronchospasm.
• Mai ka ʻaoʻao o ka pūnaehana loko ma waena: nā dizzness, nāwaliwali, ka lohe pepeiao, ka ʻeha, ka tinnitus.

ʻO ka hopena o ka hopena, ka huhū i ka wā e palaki ai i ko ʻoukou mau niho, ka wahaebleeds e kū pono ana i ke kua o ka pilikia hypertensive e hoʻomaopopo pinepine ʻia. Nui nā maʻi e hoʻopiʻi ana i ka puʻuwai kalepona ma hope o ka lawe ʻana iā Acecardol.

Inā ʻoe e hopohopo nei no nā hopena ʻokoʻa, ʻaʻole pono ʻoe e hoʻohiolo e lawe iā Acekardol. E kamaʻilio me kāu kauka inā hiki iā ʻoe ke hāʻawi i ka acetylsalicylic acid a i ʻole e hoʻololi iā ia i kahi mea ʻē aʻe. Hoʻomaopopo nā kauka lapaʻau o nā haole ma ka manawa mua ma hope o ka pau ʻana o ka hoʻokomo o ka aspirin i kēlā me kēia lā i nā mea maʻi, nā maʻi koko, ke hōʻeha ʻana i ka naʻau, a me ka stroke ischemic i ka hopena o ka "hopena hou".

Ke keu

ʻO nā hōʻailona o kahi overdose o ka hōʻemi nui o ka hōʻino: ka nausea, ka luaʻi, ka tinnitus, ka nalowale lohe, ke kaumaha, nā haunaele ʻike, nā haunaele.

Hoʻolālā: hoʻemi hōʻemi.

ʻO ka nui o ka overdose o Acecardol e hoʻoweliweli i ka edema pulmonary, hopu i ka cardiac, ka hopena ʻole o ke aʻalolo, hyperglycemia a me hypoglycemia. Ma ka hihia o ka overdose koʻikoʻi, loaʻa kahi nui ma ka hoʻolālā wikiwiki o ka gastric a me ka ʻōpū o ka ʻōpū.

Ma kahi o ka nui o ka hoʻohālikelike nui, kāʻei ʻia nā ʻano hana penei: ʻo ka mālama ʻana i ka hoʻokaʻina kūikawā i nā keʻena kūikawā no ka hōʻeha o ka maʻi gast - lavage gastric, hoʻoholo ʻana i ke kaupaona ʻana o ka acid-base, alkaline a me nā diuresis alkaline paʻa, hemodialysis, ka hoʻoponopono o nā mea hoʻoponopono, ka uluna i hoʻōla ʻia, nā hana hōʻailona.

Nā pālua:

• ka huhū haole,
• ʻuhū ka ʻūhā, gastrointestinal ulia,
• ʻO ka pupuna bronchial i ke kahua o ka hoʻonui a me ke kala ʻana,
• hemorrhagic diathesis,
• nāwaliwali o ka puʻuwai
• keiki malalo o 18 makahiki,
• ka polyposis o ka sinus paranasal a me ka ihu.

Ke pāpā ʻole ʻia nei e lawe i ka lāʻau lapaʻau Acekardol, nā mea waiwai a me ka hoʻomākaukau e like me nā manawa gestation (ʻo ka manawa holoʻokoʻa o ka hapai) a me ka ʻōpū. Hiki pū kekahi contraindication e pili ana i ka nānā ʻana o nā mea āpau i ka acetylsalicylic acid a me nā mea kōkua i ka hoʻopili o ka lāʻau, i ka lactose kikoʻī.

Contraindicated i ka maikaʻi ʻoi aku ka maikaʻi (ʻo ka cleince clearance (CC) ma mua o 30 ml / min). Me ka makaʻala a ma lalo o ka nānā ʻana o ka loea kūikawā, i kuhikuhi ʻia kahi lāʻau lapaʻau no ka hana ʻana i nā maʻi koʻikoʻi (CC ma mua o 30 ml / min).

ʻO nā analogs Acecardol, papa inoa

ʻO ke kumumanaʻo Acecardol nā mea kanu (papa inoa):

Mea koʻikoʻi - nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana o Acecardol, ke kumukūʻai a me nā loiloi ʻaʻole pili ʻia i nā analogues a ʻaʻole hiki ke hoʻohana ʻia i alakaʻi no ka hoʻohana ʻana i nā lāʻau lapaʻau o nā ʻano like ʻole a i ʻole hopena. Pono nā ʻōlelo lapaʻau āpau e pono e ke kauka. Ke hoʻololi nei iā Acecardol me kahi mea hoʻohālike, pono pono e kiʻi i nā ʻōlelo aʻo loea, pono paha ʻoe e loli i ka papa o ka lāʻau, dosages, a me nā mea pono ke hoʻāʻo pono iā ʻoe iho!

He kūpono nā loiloi o nā kauka e pili ana i ka lāʻau lapaʻau Acekardol. Wahi a nā kauka he maikaʻi nā pāpaʻi no ke pale ʻana i ka hoʻoulu ʻana o ka puʻuwai hōʻeha, nā hōʻeha, a me ka thrombosis ma hope o ka hoʻomaʻamaʻa ʻana a hana i kahi koina maikaʻi o kā lākou hana.

ʻO ka poʻe maʻi i hōʻa ʻia i ke ʻano o ka ʻoihana e ʻōlelo ʻoe inā ʻaʻole ʻoe e palau i ka papa, a laila ʻaʻole ʻia kahi pōʻino i loko o ka ʻōpū ma hope o ka lawe ʻana i ka ʻai. Hāʻawi kēia i ka kuhi hāmeʻa o ka papa papa o ka lāʻau lapaʻau. ʻO ka mea nui ka hoʻokō wale ʻia ʻana i ka pona i ʻōlelo ʻia e kāu kauka. Eia nō kekahi, ʻo ka ʻoiaʻiʻo o ka dinamics maikaʻi i ka pale ʻana a me ka mālama ʻana i nā maʻi koko, ua hōʻike ʻia nā mea maʻi.