Pehea e hoʻohana ai iā Lorista ND no ka maʻi maʻi

ʻO ka mea hana a Lorista ʻo losartan, he mea hiki ke pale i ka ʻāpoʻao o ka ʻāpoʻopau ke ala (wasiotensin 2) i loko o ka puʻuwai, nā ʻōpū, nā kīʻaha koko, a me nā cortex adrenal, e hōʻea ana i ka vasoconstriction (ka ʻikepili ʻana i ka lumen o ka lāʻau), he hōʻemi i ka huina o ke kūloko o peripheral a, ma muli o kēia, he kahe o ke koko.

Ma ke hihia o ka puʻuwai naʻau o Lorista, hōʻoia nā loiloi e hoʻonui nui ana i ka hoʻomanawanui o ka poʻe maʻi me ka hoʻoikaika kino, a pale pū i ka hoʻomohala ʻana o ka hypocrial myocardial. Hiki ke mālama ʻia ka mea nui loa o ka losartan i ke koko 1 hola ma hope o ka hoʻokele waha ʻana o Lorista, ʻoiai nā metabolits i hoʻokumu ʻia i loko o ka ate e hoʻomaka e hana ma hope o nā hola 2.5-4.

ʻO Lorista N a me Lorista ND ka hui pū ʻana o nā lāʻau lapaʻau, nā mea kūlohelohe e pili ana i ka losartan a me hydrochlorothiazide. Ua wehe ʻia ka hopena diuretic o ka Hydrochlorothiazide, kahi o ka hiki ke hana i ka waiwai ke hoʻopiʻi i nā ʻōnaehana o ka lua o ka urination, ʻo ia ka reabsorption (kahuhina) o ka wai, magnesium, potassium, chlorine, sodium ion, a me ka hoʻolohi i ka hoʻonui ʻana o ka uric acid a me nā meons calcium. He waiwai hypotensive ka Hydrochlorothiazide, i ho'ākāka ʻia e kāna hana e pili ana i ka hoʻonui ʻia o ka arterioles.

Hiki ke mālama ʻia ka hopena diuretic o kēia ʻano i loko o nā hola 1-2 ma hope o ka noi ʻana o Lorista N, aʻo ka hopena hypotensive e kūkulu i nā lā 3-4.

Nā ʻōmike Lorista

Hoʻomaopopo ke aʻo i ka hoʻohana ʻana i ka lāʻau lapaʻau Lorista inā:

• haehae maʻi
• waiho i ka hypertrophy ventricular a me ka hypertension arterial i mea e hōʻemi ai i ka hopena o ka hoʻi,
• ka huhū puʻuwai hemahema, ma ke ʻano he hui hui
• nephrology i nā maʻi me ka diabetes mellitus type 2 i mea e hōʻemi ai i ka protenuria (ʻo ke kahe o ka protein i ka urine).

Wahi a nā ʻōlelo kuhikuhi, ua kuhikuhi ʻia ʻo Lorista N inā pono, i hui pū ʻia me ka lāʻau antihypertensive a me ka diuretics.

Nā Hoʻohui

ʻO Lorista, ka palapala noi e pili ana i nā ʻōlelo lapaʻau ma mua, ʻaʻole i kuhikuhi ʻia no ke kahe koko haʻahaʻa, dehydration, hyperkalemia, intolerance lactose, ka maʻi o ka puʻukū a me ka galactose absorption syndrome, hypersensitivity a losartan. E haʻalele ʻoe i ka hoʻohana ʻana iā Lorista no nā maʻi hānai a me nā umauma hānai, a me nā poʻe ma lalo o ka 18 o ka makahiki. ʻO Lorista N, i ka hoʻohui i nā contraindications i luna, ʻaʻole i kuhikuhi ʻia no ka pilikia o ka ulia pōpilikia a i ʻole hepatic function and anuria (ka hapa o ka urine i ka wila).

Me ka mālama aka, pono e lawe ʻia nā papa o Lorista i nā poʻe me ka lēho a i ʻole hepatic insufficiency, me ka koina o ka wai-electrolyte impaired, me ka hoʻemi ʻana o ke koko kahe.

Nā ʻōkuhi no ka hoʻohana ʻana iā Lorista

Loaʻa ʻo Lorista i ka ʻaoʻao o nā papa i loaʻa iā 100, 50, 25 a iʻole 12.5 mg o ka potassium losartan. ʻO ka lāʻau e pono e lawe ʻia i ka lā hoʻokahi i ka lā hoʻokahi.

Ma ka hihia o ka hypertension arterial, i mea e hōʻemi ai i ka hopena o ka ʻeha, ʻo ia hoʻi e pale i nā keiki i nā maʻi me nā maʻi mellitus, ʻāpono ʻia nā papa no Lorista e lawe i nā papa Lorista i loko o kēlā me kēia lā o 50 mg. Inā pono, e hoʻokō i kahi hopena hou aʻe, hiki ke hoʻonui ʻia ke ʻano iā 100 mg i kēlā me kēia lā. Wahi a nā loiloi, kūkuluʻo Lorista i kāna hopena antihypertensive ma loko o nā papa he-6-6 o ka mālama ʻana. Me ka hoʻokaʻawale ʻana o nā hala o nā diuretics kiʻekiʻe, pono ke hoʻohana ʻia o Lorista me 25 mg i kēlā me kēia lā. Eia kekahi, ʻoi aku ka haʻahaʻa o ka lāʻau i kauoha ʻia no ka poʻe me ka hana naʻau lēʻa.

I ka hihia o ka nele o ka maʻi, ka lāʻau Lorista, pili ka noi i ka lawelawe like me ka diuretics a me ka glycosides cardiac, hoʻohana ʻia ia e like me kahi kumumanaʻo. I loko o ka hebedoma mua o ka mālama ʻana, pono ʻo Lorista e lawe i ka 12.5 mg i kēlā me kēia lā, a laila ma kēlā me kēia pule e hoʻonui ʻia ka pā o kēlā me kēia lā e 12.5 mg. Inā lawe pololei ʻia ka lāʻau lapaʻau, e hoʻomaka ka hopena o ka lāʻau lapaʻau me ka 50 mg o Lorista i kēlā me kēia lā. Pono e hoʻomau ʻia ka hana hou me Lorista me kahi maʻi mālama mālama o 50 mg.

ʻO Lorista N kahi papa pā i loaʻa 50 mg ka losartan a me 12.5 mg o ka hydrochlorothiazide.

Loaʻa nā papa o Lorista ND i ka hui like o nā mea like, ʻelua wale nō ka nui - 100 mg o ka losartan a me 25 mg o ka hydrochlorothiazide.

Me ka hypertension arterial, ʻōlelo ʻia i kēlā me kēia lā o Lorista N no 1 papa, inā pono, 2 papa i kēlā me kēia lā. Inā hōʻemi ka mea maʻi i ka nui o ke koko kahe, pono e hoʻomaka ka lāʻau lapaʻau me ka maʻi o kēlā me kēia lā o 25 mg. Pono e lawe ʻia nā papa no Lorista N ma hope o ka hoʻoponopono ʻana i ka nui o ke koko kahe a me ka hoʻopau ʻana i nā diuretics.

Wahi a nā loiloi, ʻike ʻia e lawe iā Lorista N i ka hopena o ka maʻi cardiovascular inā ʻaʻole i kōkua ka losartan monotherapy i ka hopena o ke ana o ke koko. ʻO ka ʻōlelo paʻa o ka lāʻau lapaʻau i kēlā me kēia lā he 1-2 papa.

Nā hopena hopena

Nā hopena hopena o nā papa Lorista a me nā hoʻokolohua hoʻopaʻa i ka:

• hōʻeha, ka ʻōpū, ka ʻeha, ka dizziness, asthenia, ke ahonui, hoʻomanaʻo ʻana, ke kahe, migraine, ke kaumaha,
• hypotension dosis-hilinaʻi, bradycardia, tachycardia, palpitations, angina pectoris, arrhythmia, vasculitis,
• bronchitis, waʻai, pharyngitis, honestest hidal a i ke hamu paha, pōkole o ka hanu,
• ʻeha ka ʻōpū, ʻeha, ʻōpū, waha maloʻo, anorexia, gastritis, flatulence, constipation, puka, hōʻeha o ka ʻōpū, ka huina o ka ate, hepatitis,
• urinary tract maʻi, urrollally control, impaired renal function, hoʻonui serum creatinine a me Urea,
• ka hoʻemi ʻana i ke kaʻa ka hana, ka impotence,
• ʻeha ma hope o nā ʻūhā, nā ʻūhā, nā umauma, nā ʻeha o ka naʻau, ka ʻōpū, ka arthralgia,
• conjunctivitis, ʻikeʻole i ka ʻike, ʻono ʻano, tinnitus,
• ʻO ka erythema (ʻulaʻula o ka ʻili, hoʻonāukiuki ʻia e ka hoʻonui ʻia o nā kapillaries), hoʻonui nui loa, ka maloʻo maloʻo, phytosensitization (hoʻonui nui i ka radiation ultraviolet), nui ka lau o ka lauoho.
• gout, hyperkalemia, anemia,
• angioedema, ʻohiʻoki, ʻeha, urticaria.

E like me ke kānāwai, nā hopena maikaʻi loa o nā huaʻōlelo ʻo Lorista i loaʻa ka hopena pōkole a me ka nāwaliwali.

ʻO ka hopena ʻaoʻao o Lorista N i nā mea like ʻole e like me nā hopena o kahi mea ola i ke noi ʻana iā Lorista.

ʻŌpū a me ka lactation

ʻO ka ʻikepili epidemiological e pili ana i ka hopena o ka teratogenicity i ka wā e lawe ai i nā inhibitor ACE i loko o ka trimester mua o ka hānau ʻana, ʻaʻole ia e ʻae i ka hopena hope loa, akā ʻaʻole i ʻae ʻia kahi māhina o ka pilikia. ʻOiai ka ʻike ʻole ʻana o ka ʻikepili epidemiological e pili ana i ka teratogenicity o ARA-I, ʻaʻole hiki ke hoʻokaʻawale ʻia nā pilikia like ʻole ma kēia pūʻulu o nā mea lapaʻau. Inā ʻaʻole hiki iā ia ke hoʻololi i ka ARA-I me nā ala ʻē aʻe, e huli ʻia nā mea maʻi e hoʻolālā ana i ka hāpai ʻana i ka lāʻau lapaʻau, kahi e hoʻomaopopo pono ai ka ʻike palekana. Ke ulu mai ka wā hāpai, ʻo ARA-pono e pani koke ʻia wau, a inā he pono, pono ke kau ʻia o nā lāʻau ʻē. Me ka hoʻohana ʻana o ARA-I i ka lua o ke kolu o ka hapo o ka hapai, kahi hōʻike i kahi hopena fetotoxic (hana ʻole ʻia ka hopena, oligohydroamniosis, lohi i ka pīpī iwi o nā iwi ʻihiʻā) a me nā meaʻeha neonatal (pilikia ʻole, hypotension, hyperkalemia) i hoʻokumu ʻia. Inā lawelawe ʻia ʻo APA-II ma ka lua o ke kolamu o ka hapalua o ka hapai ʻana, e hoʻomaopopo ʻia e hana i kahi ultrasound o nā iwi o nā ʻōpala a me nā iwi. I nā pēpē hou i lawe aku ai nā makuahine iā ARAL, pono pono e nānā pono i ke kahe o ke koko e pale ai i ka hiki ke kūkulu ʻia o ka hypotension.

Hoʻolaha ka ʻike e pili ana i ka hoʻohana ʻana iā hydrochlorothiazide i ka wā hapai, inā no ka trimester mua. Hoʻopaʻi ka Hydrochlorothiazide i ka plasenta. Hoʻokumu i ka mākeke lāʻau o ka hana, hiki ke hoʻopaʻapaʻa i kona hoʻohana ʻana i ke kolamu o ka lua a o ke kolamu o ka hapai i hiki ke hoʻonāukiuki i ka make Plusion a me ka hana ʻana i nā pilikia i loko o ka pūpū a me ka pēpē, e like me ka jaundice, electrolyte imbalance a me thrombocytopenia. ʻAʻole pono ke hoʻohana ʻia ka Hydrochlorothiazide no ka edema gestational, hypertension gestational a i ʻole ke toxicosis o ka hāpai ʻana ma muli o ka hopena o ka hoʻemi ʻana o ka nui o ka plasma a me ke kūkulu ʻana o ka hypoperfusion placental i ka lilo ʻole o kahi hopena kūpono i ka papa o ka maʻi.

ʻAʻole pono e hoʻohana ʻia ʻo Hydrochlorothiazide e mālama i ka hypertension primert arela wahine i loko o nā wahine hāpai, me kaʻole ʻole o kēlā mau hihia i loaʻa ʻole ke hoʻohana i nā ʻano aʻoaʻo ʻē aʻe.

ʻAʻohe ʻikepili i ka hoʻohana ʻia ʻana o ka lāʻau lapaʻau Lorista ND i ka wā o ka ʻōpū. Pono e hoʻohālikelike ʻia ke ʻano hana me ka hoʻohana ʻana i nā lāʻau lapaʻau i hōʻike ʻia i ke ʻano o ka palekana i ka wā o ka lactation, ʻoi aku ka hānai ʻana i nā pēpē a i ʻole pēpē keiki.

ʻLoe a me ke kākele

Ke ʻae ʻia ka lāʻau e lawe pū ʻia me nā lāʻau lapaʻau antihypertensive.

Hiki ke kiʻi ʻia ka lāʻau e pili ana i nā mea o ka ʻai.

Pono e holoi ʻia ka papa ʻaina me kahi aniani o ka wai.

ʻAʻole paʻa ka hui pū ʻana o ka losartan a me hydrochlorothiazide no ka hana mua ʻana, ua hōʻike ʻia ka hoʻohana ʻana i nā hihia me ka hapa ʻole o ke kaomi o ke koko me ka hoʻohana ʻana i ka losartan a me ka hydrochlorothiazide. Hoʻonohonoho ʻia nā kaha titration o nā pona. Inā makemake ʻia ia ʻo ka ʻoihana ʻoihana, pono e noʻonoʻo i ka hoʻololi ʻana mai ka monotherapy i ka hoʻohana ʻana o kahi hui me kahi maʻi paʻa.

ʻO ka papa mālama maʻi maʻamau ka 1 papa o Lorista N (losartan 50 mg / hydrochlorothiazide 12.5 mg) hoʻokahi i ka lā.

Me ka pane paneole ʻole e hiki ai ke hoʻonui ʻia, hiki ke hoʻonui ʻia i ka nui i 1 papa o Lorista ND (losartan 100 mg / hydrochlorothiazide 25 mg) hoʻokahi i ka lā. ʻO ka nui loa o ka maʻa he 1 papa o Lorista ND (losartan 100 mg / hydrochlorothiazide 25 mg) i kēlā me kēia lā.

Ma ke ʻano he kānāwai, ua hoʻokō ʻia ka hopena hypotensive i loko o nā hebedoma 3-4 ma hope o ka hoʻomaka ʻana o ka hōʻola.

Hoʻohana ma ka hihia o kahi hana renal impaired a ma nā mea maʻi ma ka hemodialysis I nā maʻi me ka hōʻeha ʻole o ka renal (clearance creince o 30-50 ml / min), ʻaʻole koi ʻia kahi hoʻoponopono hoʻoponopono mua. ʻAʻole ia e kuhikuhi i kēia hoʻohui no ka hana pūlea i loaʻa i ka maʻi koʻikoʻi

Ke keu

ʻO nā ʻike kikoʻī e pili ana i ka overdose o ka Hoʻohui Kūleʻa 50 mg / Hydrochlorothiazide Hoʻohui

12.5 mg ua hala.

Hoʻomaʻikaʻi ka mālama ʻana, kākoʻo.

Ma kahi o kahi overdose, pono e hoʻokaʻawale ke ʻano lāʻau lapaʻau, a pono e hoʻoneʻe ʻia ka mea maʻi ma lalo o ka mākaʻikaʻi koʻikoʻi. Inā ua lawe hou ʻia ka lāʻau lapaʻau hou, e hāpai i ka hoʻoulu ʻana, a me ka hoʻohana ʻana i nā ala ʻike ʻike e hoʻokō ai i nā hana pale e pili ana i ka hoʻopau ʻana i ka dehydration, palauleʻa electrolyte, pāpaʻi hepatic a me hypotension.

Hoʻohui ka ʻikepili overdose. Hiki i nā hōʻailona, ​​nā hōʻailona maʻamau: hypotension, tachycardia, bradycardia (ma muli o ka parasympathetic (ma muli o ke kuʻuna). Ke hele a hōʻailona ka hypotension, pono e kuhikuhi ʻia ka mālama ʻana.

ʻAʻole hiki ke hoʻopau ʻia ka losartan a me kāna metabolite ikaika e ka hemodialysis.

ʻO nā hōʻailona a me nā hōʻailona maʻamau, "hypokalemia, hypochloremia, hyponatremia (ma muli o ke kahe ʻana o nā pae electrolyte) a me ka pulu (no ka diuresis nui). Inā i kuhikuhi ʻia i ka digitalis i ka manawa like, hiki i ka hypokalemia ke alakaʻi i ka exacerbation o ka arrhythmia cardiac.

Ehia ka nui o ka hydrochlorothiazide i waho i ka hemodialysis ʻaʻole i ʻike ʻia.

Hoʻopili pū me nā lāʻau ʻē aʻe

ʻO ka Rifampicin a me fluconazole e hōʻemi i ka paneʻana o ka metabolite ikaika. ʻAʻole i aʻo ʻia nā hopena koʻikoʻi o kēia maʻi.

E like me nā lāʻau lapaʻau ʻē aʻe e ālai ana i ka angiotensin II a i hōʻemi paha i kona hopena, ka hoʻohana pono ʻana o ka pā diuretics potassium-sparing (spironolactone, triamteren, amiloride), a me nā hoʻohui me ka paʻakai a me nā loaʻa o ka paʻakai hiki ke alakaʻi i ka hoʻonui ʻana o ka paʻakai i ka plasma koko. ʻAʻole kōkua ʻia ka hoʻohana pinepine ʻana i kēia mau lāʻau.

E like me nā lāʻau ʻē aʻe e pili ana i ka sodium excretion, hiki i ka losartan ke hōʻemi i ka hoʻonuiʻana o ka lithium mai ke kino. No laila, me ka hoʻohana pinepine ʻana o APA-II a me ka paʻakai lithium, pono pono e nānā pono kekahi i ka pae o ka hopena o ka plasma koko.

Me ka hoʻohana pū ʻana o APA-II a me nā lāʻau anti-inflammatory non-steroidal (NSAIDs) (no ka laʻana, ka palupalu māpala cyclooxygenase-2 (COX-2), ka acetylsalicylic acid i nā wai anti-inflammatory a me nā NSAID-koho ʻole), nā hopena hypotensive e nawaliwali. ʻO ka hoʻohana maʻamau Pono e hoʻohana pū ʻia kēia hui me ka makaʻala, keu i nā pākeke. Pono nā mea maʻi e loaʻa i ka nui o ka wai o ka wai, pono nō hoʻi e nānā i ka nānā ʻana i nā hiʻohiʻona hana o nā pūpū ma hope o ka hoʻomaka ʻana o ka concomitant therapy a me ka manawa maʻamau i ka mālama ʻana.

I kekahi mau mea maʻi me ka hana renal impaired, ʻo ia hoʻi. COX-2 inhibitors, hoʻopili paʻa ʻana o APA-II hiki ke alakaʻi hou aku i ka hoʻopilikia ʻana i ka hana māla. Eia nō naʻe, hōʻano hou kēia hopena.

ʻO nā lāʻau'ē aʻe me nā hopena hypotensive he tricyclic antidepressants, nā lāʻau antipsychotic, baclofen a me amifostine. ʻO ka hoʻohana pū ʻana o losartan me kēia mau lāʻau lapaʻau ka hoʻonui i ka hopena o ka hypotension.

Me ka hoʻohana pū ʻana o ka diuret thiazide a me nā huaʻala e hiki mai ana, e ʻike ʻia ka launa pū ʻana.

Ethanol, barbiturates, nā lāʻau lapaʻau narkotic a me nā antidepressants.

ʻO ka lāʻau antidiabetic (waha a me ka insulin)

ʻO ka hoʻohana ʻana i ka thiazides e pā paha i ka hoʻohaʻahaʻa glucose, ma muli o kahi hopena e hoʻonā hou ai i kahi lāʻau lapaʻau antidiabetic. Pono e hoʻohana me Metformin me ka makaʻala no ka loaʻa ʻana o ka acidosis lactic i kumu no ka hiki ʻole o ka hana pono ʻole i pili me ka hoʻohana ʻana i ka hydrochlorothiazide.

ʻO nā lāʻau lapaʻau antihypertensive Hoʻohui hou.

Nā resolilo Cholestyramine a me colestipol

Hoʻemi ʻia ka komo ʻana o ka hydrochlorothiazide i ka wā i ʻike ʻia ai i loko o nā anion ke hoʻololi hou ʻana. Hoʻomoe kahi kakala o ka cholestyramine a i ʻole colestipol resins e hoʻopaʻa i ka hydrochlorothiazide, e hōʻemi ana i kona komoʻana ma ka gastrointestinal tract e 85% a 43%, kekahi. He corticosteroids, adrenocorticotropic hormone (ACTH)

ʻO ka hōʻemi hoʻopiʻi ʻia i loko o ka paʻa ʻana o nā electrolytes (ma ke ʻano, hypokalemia). Nā mea hana mana (e.g. adrenaline)

He hiki ke hoʻonāukiuki i ka hana ʻana i nā mea paʻi pressor, ʻo ia hoʻi, ʻaʻole lawa e pale i kā lākou hoʻohana.

ʻO ka hoʻomaha ʻana i loko o nā māla, nā mea hōʻihoʻi ʻole i ka hoʻoneʻe ʻana i nā lālani (e.g. tubocurarine) hiki ke loaʻa i ka ʻāʻī o nā mea hōʻeha kino.

Hoʻopau ka diuretics i ka hoʻomaʻemaʻe i kahi o ka lithium a hoʻonui i ka hopena o nā hopena o nā āʻā. ʻAʻole kūkākūkā ʻia ke kākoʻo ʻana.

ʻO nā lāʻau lapaʻau i hoʻohana ʻia e mālama i ka gout (probenecid, sulfinpyrazone a me allopurinol)

Hoʻololi ʻia kahi hopena o kahi lāʻau lapaʻau e hoʻolako nei i ka ʻāwili ʻana o ka waikū uric, ʻoiai ke hoʻohana ʻia ka hydrochlorothiazide hiki ke hoʻonui i ka kahe o ka waikiko uric i loko o ke kaila koko. Hiki paha iā ʻoe ke hoʻonui i ka maʻa o ka probenicide a sulfinpyrazone paha. Hiki i nā lāʻau Thiazide ke hoʻonui i ka hiki i ka ulu ʻana o ka hypersensitivity i allopurinol.

Anticholinergics (e.g. atropine, biperiden)

Ma muli o ka nāwaliwali o ka motility gastrointestinal a pani ʻole i ka ʻōpū, hoʻonui i nā bioavailability o ka diuretics thiazide.

ʻO nā hui Cytotoxic (e.g. cyclophosphamide, methotrexate)

Hiki i ka Thiazides ke hōʻemi i ka hoʻonui ʻana i nā lāʻau cytotoxic i loko o ka komi a me ka hoʻokaʻawale i kā lākou hana i manaʻo ai e kāohi i ka hana o ka mahi a nā iwi.

Ke noi nei i nā dosis kiʻekiʻe o ka salicylates, hiki i ka hydrochlorothiazide ke hoʻonui i ko lākou hopena o nā pona i ka paena nīnaehana. ,

Ua hōʻike ʻia nā hihia kūʻokoʻa o ka anemia hemolytic me ka hoʻohana pū ʻana o ka hydrochlorothiazide a me ka methyldopa.

ʻO ka hoʻohana pinepine ʻana o ka cyclosporine e hoʻonui i ka hōʻeha o ka hyperuricemia a me nā hoʻopiʻi gouty.

ʻO ke hypokalemia a i ʻole hypomagnesemia i hoʻoiho ʻia e ka thiazide diuretics hiki ke alakaʻi i kahi hoʻouka ʻana o ka arrhythmia cardiac i hoʻokumu ʻia e ka digitalis.

Nā lāʻau lapaʻau e hoʻololi ai kāna hana me kahi loli i ka pae o ka paʻakai ma ke koko

Hoʻomaopopo iki ka manawa o ka paʻakai pākela a me ka nānā ʻana o ka ECG i nā hihia me ka hoʻohana pū ʻana o ka hui losartan / hydrochlorothiazide a me nā lāʻau lapaʻau, ka hopena o ia mea e pili ana i ke kālai ʻia o ka pāhana pākīpī i loko o ke koko koko (me ka laʻana, ka digitalis glycosides a me nā lāʻau antiarrhythmic), a me nā lāʻau lapaʻau hoʻi e kumu "torsades de pointes" ( tachycardia ventricular), me kekahi mau lāʻau antiarrhythmic (hypokalemia he predisposing o ka ventachular tachycardia):

pauku 1a mau lāʻau lapaʻau antiarrhythmic (quinidine, hydroquinidine, disopyramide), nā papa III antiarrhythmic drug (amiodarone, sotalol, dofetilide, ibutilide),

kekahi mau lāʻau antipsychotic (thioridazine, chlorpromazine, levomepromazine, trifluoperazin, cyamemazine, sulpiride, sultopride, amisulpride, unggalride, pimozide, haloperidol, droperidol).

ʻO kekahi (bepridil, cisapride, difemanil, erythromycin (no ka hoʻokō intravenous), halofantrine, misolastine, pentamidine, terfenadine, vincamine (no ka hoʻokō intravenous)).

Hiki i nā Thaizide diuretics ke hoʻonui i ka kaila o ka paʻakai kalima i loko o ke koko koko ma o ka hōʻemi ʻana i kā lākou excretion. Inā pono, ʻo ke koho ʻana i kēia mau lāʻau e pono e kiaʻi i ka ʻike o ka calcium a, e like me nā hopena, e hoʻokō ʻia ka hoʻoponopono ʻana o ka maʻi.

Hoʻomaʻaʻa i nā hopena laboratory

Ma ka hoʻopilikia i ka metabolism o ka calcium, hiki i ka thiazide diuretics ke hoʻokaʻawale i nā hopena o nā noi ʻana o ka hana o nā kīnaka parathyroid.

Aia kahi hopena o ka hyponatremia hōʻailona. Pono ke nānā ʻana me ke nānā ʻana a me ke olakino.

I ka hihia o ka dehydration i hoʻoiho ʻia e ka diuretics, ʻoi ka nui o ka hōʻemi o ka hana ʻana i ke aʻa o ka maʻi me ka nui o ka iodine, i nā nui kiʻekiʻe o nā lāʻau lapaʻau e lako ai. Ma mua o ka hoʻohana ʻana i ia ʻano mea, pono e hoʻomaʻamaʻa ʻia ka mea maʻi.

Amphotericin B (no ka hoʻokele makua), corticosteroids, ACTH a i ʻole stimulant laxatives

Hiki i ka Hydrochlorothiazide ke hoʻonui i ka palupalu electrolyte, ʻoi aku hoʻi i ka hypokalemia.

Nā hiʻohiʻona noi

Hoʻomaopopo i ka hiki ke alakaʻi i kahi kaʻa a i ʻole nā ​​mīkini ʻē aʻe I ka hana ʻana i nā hana e koi nui ai ka nānā (ka lawe ʻana i kahi kaʻa, hana pū me nā mīkini paʻakikī), pono e hoʻomanaʻo ʻia i ka hoʻoluhi hypotensive i kekahi manawa e hoʻolilo ai i ka huki a me ka hiamoe, a ma ka hoʻomaka ʻana o ka hoʻōla a i ka wā e hoʻonui ʻia ka hopena.

ʻO nā mea mālama palekana

ʻO ka mea maʻi me ka mōʻaukala o ka angioedema pono ma lalo o ka mākaʻi koʻikoʻi ma lalo o ka mālama koʻikoʻi (ka huki o ka maka, nā lehelehe, ka ʻōpū, a me / a i ʻole ka ʻōlelo).

ʻO ka hypotension a me ka hoʻohaʻahaʻa o ka volume intravascular

I ka poʻe maʻi me ka hypovolemia a me / a i ʻole hyponatremia (ma muli o ke ʻano diuretic intensive, heʻai me ka hoʻēmi ʻana o ka sodium, maʻi ʻana a i ʻole luaʻi), hiki mai paha ka hypotension, ma hope o ka lawe ʻana i ka ʻaina mua. Ke koi nei kēia mau kūlana i ka hoʻoponopono ʻana ma mua o ka hoʻomaka ʻana o ka mālama ʻana.

Hoʻopiʻi ka piliona

Loaʻa ka nānāʻole o Electrolyte i nā mea maʻi me ka hiki ʻole o ka renal, ʻoi aku ka nui o ka maʻi maʻi. No laila, i ka wā o ka hoʻōla, ʻo ka ʻike o ka pāhana i loko o ke kaila koko a me ka hoʻopiʻi ʻana o nā mea mai ka kiaʻi, pono, i loko o nā mea maʻi me ka cleinine clearance o 30 - 50 ml / min.

Hōʻeha ka naʻau ʻili

Pono ka lāʻau ʻo Lorista ND e mālama me ka mālama aka i nā poʻe maʻi me ka mōʻaukala o ka hana maʻalahi a me ka palaualelo.

ʻOiai inā ʻaʻohe data e pili ana i ka hoʻohana ʻana i ka hopena o ka losartan i nā mea maʻi me ka maʻi hepatic koʻikoʻi, ua hoʻohana ka lāʻau lapaʻau Lorista ND i kēia māhele o nā maʻi. i i

Hola paʻa kino hana

Ma muli o ke kaohi ʻana o ka renin-angiotensin-aldosterone-1g-system, nā loli i ka hana ʻoi, me ka renal gagal, i ʻike ʻia (i loko nō i nā mea maʻi me ka paulele ʻana o ka hana renal ma ka ʻōnaehana renin-angiotensin-aldosterone: nā mea maʻi me ka hōʻeha pū o ka naʻau a i ʻole me ka hana ʻole ʻana o ka renal).

E like me nā lāʻau ʻē aʻe e pili ana i ka ʻōnaehana renin-angiotensin-aldosterone, nā maʻi me ka bilateral renal stenosis stenosis a i ʻole stenosis kūloko o kahi keiki hoʻokahi i hōʻike i ka hoʻonui ʻana o ka urea a me nā pae hana, ua hoʻohuli ʻia kēia mau loli i ka wā e hoʻokuʻu ʻia ai ke ʻano. E hoʻohana i ka akahele me ka losartan i nā mea maʻi me ka stenosis bilateral renal aren stenosis a i ʻole stenosis artery o ke keiki hoʻokahi.

ʻAʻohe ʻikepili i ka hoʻohana ʻana i ka lāʻau lapaʻau i nā mea maʻi e hoʻomanawanui nei i ka hōʻemi.

I ka poʻe maʻi me ka hyperaldosteronism maʻamau, ma ke ʻano he kānāwai, ʻaʻohe hopena o ka lāʻau antihypertensive e kāohi ana i ka ʻōnaehana renin-angiotensin. No laila, ʻaʻole i ʻōlelo ʻia ka hoʻohana ʻana o ka hui ʻana o ka losartan / hydrochlorothiazide.

ʻO ka maʻi ʻeha Coronary a me nā maʻi cerebrovascular

E like me nā lāʻau āpau antihypertensive, ʻo ka nui o ka hoʻemi ʻana o ke kao nui i loko o nā mea maʻi me ka maʻi naʻau coronary a me ka maʻi cerebrovascular hiki ke alakaʻi i myocardial infarction a i ʻole hahau. Haki puʻuwai

ʻO ka maʻi me ka puʻuwai puʻe (me ka ʻole ʻole o ka renal gagal) i loaʻa ka nui o ka ulu ʻana o ka ulu ʻana o ka hypotension arterial nui a me ka hoʻomaʻamaʻa ʻole ʻana i ke kino (pinepine aʻeha hoʻi).

ʻO ka stenosis a me ka aortic valve stenosis, obstructive hypertrophic cardiomyopathy

E like me nā vasodilator e pono, e mālama ʻia ka mālama kūikawā ʻana i ka wā e lawelawe ai i ka lāʻau lapaʻau i nā mea maʻi me ka stenosis aortic, stenosis mitral, a me ka hypventrophic cardiomyopathy.

Hōʻikeʻike i nā mea hoʻohālikelike o ka angiotensin-hoʻololi i ka enzyme, losartan, a me nā antagonist angiotensin e hōʻike ana i ka hopena o ka hypotensive i ka wā e hoʻohana ʻia ai i ka lāhui o ka lāhui Aferika. Manaʻo paha kēia kūlana i ka mea o kēia ʻano o nā maʻi i loaʻa i kahi haʻahaʻa o renin i loko o ke koko. Kahawai

ʻAʻole pono e lawe ʻia ka Angiotensin II receptor inhibitors (ARA-I) i ka wā hāpai. Inā hiki, a laila e kuhikuhi ʻia nā mea maʻi e hāpai i kahi hapai e hoʻohuli i nā ʻano o ke ʻano antihypertensive, ka mea i hōʻoiaʻiʻo ai iā lākou iho i nā hua palekana inā hoʻohana ʻia i ka wā hāpai. Ma hope o ke kūkulu ʻia ʻana o ka hapai ʻana, pono wau e haʻalele ʻia ʻo ARA -a a me nā lāʻau lapaʻau i kauoha ʻia inā pono.

ʻO ka maʻi hāleo a me ka ʻike wai-electrolyte

E like me nā lāʻau antihypertensive ʻē aʻe, e loaʻa paha kekahi mau maʻi i ka hypotension hypertension arterial. No laila, pono e hana ʻia kahi loiloi ʻōnaehana no ka ʻike ʻana i nā hōʻailona lapaʻau e pili ana i ka nānā ʻole ʻana o ka wai-electrolyte (hypovolemia, hyponatremia, hypochloremic alkalosis, hypomagnesemia a hypokalemia), no ka laʻana, ma hope o ka maʻi ʻaʻai a i ʻole ka luaʻi. I ia mau mea maʻi, pono kahi kiaʻi pinepine ʻana i nā ʻikepili electrolyte. Pūnaewele. I ka yoga, hiki i ka poʻe maʻi e loaʻa ana i ka edema ka meli hyponatremia.

Ka hopena i ka metabolism a me ka ʻōnaehana endocrine

Hiki i ke lāʻau Thiazide ke alakaʻi i ka paleʻana i nā hoʻohaʻahaʻa glucose. pono ia i ka hoʻoponopono hoʻoponopono ʻana i nā lāʻau antidiabetic, incl. insulin Ke hoʻohana ʻia ka lāʻau thiazide, hiki i ka maʻi diabetes mellitus ke hōʻike. Hiki i ka Thiazides ke hōʻemi i ka hoʻonui ʻana o ka kalima i ka pāʻai a ma ia mea, ke alakaʻi aku nei i kahi hoʻonui manawa pōkole loa i ka hoʻonui ʻana i loko o ke koko koko. ʻO ka hypercalcemia koʻikoʻi e hōʻike i ka latpar hyperparathyroidism. Ma mua o ka nānā ʻana i ka hana o nā kūloko o ka parathyroid, pono e hoʻokuʻu i ka diuret thiazide.

Hiki ke hoʻopili ʻia ka hoʻohana ʻana i ka diuret thiazide me ka hoʻonui i ka cholesterol a me ka triglycerides.

I kekahi mau mea maʻi, hiki i ka lāʻau thiazide ke hoʻoulu i ka hyperuricemia a me / a i ʻole hoʻouka kaua ʻana i ka gout. No ka hoʻēmi ʻana o ka losartan i ka hoʻoneʻe ʻana o ka uric acid, ʻo kona hui pū me ka hydrochlorothiazide e hōʻemi i ka hopena o ka hyperuricemia pili me ka hoʻohana ʻana i ka diuretics.

Hōʻeha ka naʻau ʻili

I nā mea maʻi me ka leʻaleʻa o ka ate a me ka maʻi ʻōlohelohe holomua, pono e hoʻohana ʻia nā thiazides me ka makaʻala, no ka mea hiki iā lākou ke hōʻala i ka cholestasis intrahepatic, a me nā hoʻololi liʻiliʻi i ke kahe a me ka hoʻoliʻiliʻi electrolyte hiki ke hoʻonāukiuki i kahi koma i loko o ka puʻuwai. Lorista ND contraindicated i nā maʻi me nā maʻi hepatic koʻikoʻi.

Hiki i nā mea maʻi e hopu ana i ka thiazides e ʻike i nā hopena hypersensitivity, ʻoiai inā he mōʻaukala o lākou a me ka maʻi bronchial asthma. Aia nā mana o ka exacerbation a me ka hoʻomau hou ʻana o ka systemus lupus erythematosus me ka hoʻohana ʻana i nā lāʻau thiazide.

Loaʻa ka hopena

Ma keʻano holoʻokoʻa, mālama ʻia me ka hui ʻana o ka hydrochlorothiazide + losartan. I ka hapanui o nā hihia, he ʻoluʻolu nā hopena hopena, transient, ʻaʻole i koi i ka hoʻokuʻu ʻana o ka maʻi.

I ka hoʻokolohua ʻana i nā hoʻokolohua paʻa i ka mālama ʻia ʻana o ka maʻi hypertension, ʻo ka maʻi ʻana ka mea ʻino wale nō i pili me ka lawe ʻana i ka lāʻau, ka piʻi ʻana o ka manawa ma mua o ka waiho ʻana i kahi pletona ma mua o ka 1%. E like me ka hōʻike ʻana i nā hoʻokolohua paʻa i mālama ʻia, ka losartan i hui pū me ka hydrochlorothiazide i hoʻohaʻahaʻa ʻia ma nā maʻi me nā hypertension a waiho aku i ka hypertrophy ventricular. ʻO nā mea ʻino e hōʻike ai i ka hoʻonā systemic a me ka hoʻonāukiuki ʻole systemic, nāwaliwali / hoʻonui i ka momona. I ka wā o ka hoʻohana kau inoa ʻana o kēia hoʻohui, nā ho'āʻo lāʻau lapaʻau a me / a i ʻole hoʻohana ʻana i ke kau inoa o nā mea ikaika o ka hui ʻana, ua hōʻike ʻia nā hopena ʻē aʻe hou.

Nā pilikia mai ke koko a me ka ʻōnaehana lymphatic: thrombocytopenia, anemia, aplastic anemia, hemolytic anemia, leukopenia, agranulocytosis.

ʻO ka hanana ʻōnaehana maʻi: ka hopena anaphylactic, angioedema, me ka hoʻolei ʻana o ka larynx a me nā lipole leo me ka hoʻomohala ʻana o ka ala airway a / a me ka haki ʻana o ka maka, nā lehelehe, pharynx a / a i ʻole e ʻōlelo ai i nā mea maʻi e lawe ana i ka losartan, ua ʻike pinepine ʻia (≥0.01% a me 5.5 meq / l) i nānā ʻia ma 0.7% o nā mea maʻi, akā naʻe, i kēia mau noiʻi ʻaʻohe mea e pono e kāpae i ka hoʻohui ʻana o ka hydrochlorothiazide + losartan ma muli o ka hiki ʻana o hyperkalemia. ʻO ke hoʻonui ʻana i ka hana alanine aminotransferase hana i loaʻa iki ka maʻamau a hoʻi hou i ka maʻamau ma hope o ka hoʻokuʻu ʻana o ka maʻi.

Ke keu
ʻAʻohe ʻikepili i ka mālama kūikawā ʻana o ka overdose me ka hui pū ʻana o ka hydrochlorothiazide + losartan. Hoʻomaʻamaʻa ʻia ka hoʻomaʻamaʻa ʻana a kākoʻo. Pono e hōʻoki ʻia ka lāʻau laʻa Lorista ® ND, a ʻike ʻia ka mea maʻi. Inā lawe ʻia ka lāʻau lapaʻau i kēia manawa hou, e hōʻike ʻia e hoʻonāukiuki, a me ke kinai ʻana o ka hoʻoheheʻe ʻia, nā pilikia o ka wai-electrolyte, ka maʻi hepatic a me ka hoʻolilo ʻana i ke kahe koko e nā ala maʻamau.

Losartan
Hoʻohālikelike ka ʻike overdose. ʻO ka hōʻike maʻamau o kahi overdose he hōʻailona i hōʻemi ʻia i ke koko a me ke tachycardia, hiki i ka bradycardia ke hōʻea ma muli o ka hoʻouluʻana parasympathetic (vagal). I ka hihia o ka hoʻomohalaʻana o ka hōʻailona hypotension arterial, hōʻike ʻia ka mālama mālama ʻana.
Lāʻau: ʻano hana maʻi.
ʻAʻole kahi lawehala a Losartan a me kāna metabolite hoʻoikaika e ka hemodialysis.

ʻO ka hole waiwai
ʻO nā maʻi ʻomaʻoma loa e nānā nui ma muli o ka nele o ka electrolyte (hypokalemia, hypochloraemia, hyponatremia) a me ka dehydration ma muli o ka diuresis nui. Me ka hoʻomohala pinepine ʻana o nā glycosides cardiac, hiki i ka hypokalemia ke hoʻonāukiuki i ka papa o nā arrhythmias.
ʻAʻole i hoʻokau ʻia kahi e hiki ai ke wehe i ka hydrochlorothiazide mai ke kino e ka hemodialysis.

Ka inoa a me ka inoa o ka mea e paʻa ana (ka mea e paʻa ai) ka palapala hoʻopaʻa inoa

Mea Hana:
1. JSC "Krka, dd, Novo mesto", Šmarješka cesta 6, 8501 Novo mesto, Slovenia
2. LLC "KRKA-RUS",
143500, Lūkia, Moscow Wilayah, Istra, ul. Moskovskaya, d. 50
i ka launa pū me JSC "Krka, dd, Novo mesto", Šmarješka cesta 6, 8501 Novo mesto, Slovenia

Ke kīʻaha a me / a i ʻole i ka pēpē ma ka hui Lūkini, i hōʻike ʻia:
KRKA-RUS LLC, 143500, Lūkini, Mōkelē Moscow, Istra, ul. Moskovskaya, d. 50

ʻO ka inoa a me ka helu ʻana o ka hui e ʻae nei i ka hoʻopiʻi a ka mea kūʻai
LLC KRKA-RUS, 125212, Moscow, Golovinskoye Shosse, Ke kūkulu ʻana, 5

E hoʻokuʻu i nā palapala a me ka ʻano

Loaʻa i nā palapala papa. Kuhi ʻia no ka hoʻohana waha. Aia nā papa i kēia ʻano mea ikaika e pili ana:

• ka mea hoʻohana nui ka losartan, 100 mg,
• hydrochlorothiazide - 25 mg.

Loaʻa ka lāʻau lapaʻau i loko o kahi waihona o 12, 25, 50 a me 100 mg.

Loaʻa ka Lorista ND i ka palapala papa.

Lapaʻau lāʻau

ʻO ka piʻi nui loa o nā mea ikaika e hōʻike i hoʻokahi hola ma hope o ka lawe ʻana i nā papa. Hoʻomaʻa ka hopena therapeutic no 3-4 mau hola. Ma kahi o 14% o losartan, lawe ʻia ma ke alo, ua hoʻohuli ʻia ka metabolite i kāna metabolite ikaika. ʻO ka hapalua hapalua o losartan he 2 mau hola. ʻAʻole i hoʻohālikelike ʻia ka Hydrochlorothiazide a hoʻonui koke i nā ʻōpū.

He aha ka mea e kōkua ai?

Hoʻomaopopo ʻia ka lāʻau lapaʻau i loko o ia mau hihia:

1. He maʻi haole.
2. ʻOiai he kākoʻo kākoʻo e hōʻemi i ka make nui o ka poʻe i loaʻa i ka hypertrophy hema a i ʻole ke kaumaha hypertension kino ʻole.
3. ʻO ka pale ʻana i ka hopena o nā hōʻeha, ka hōʻeha ʻana o ka naʻau, nā hōʻino myocardial i nā ala ʻo ke ʻano o ka ʻōnaehana cardiovascular.
4. Hypersensitivity a me ka intolerance pilikino i nā inhibitors isoenzyme.
5. Hypertension arterial, ulu e kū mai ana i ke kua o ka maʻi mellitus o ka maʻi mela, pilikia ʻole.
6. ʻO ka palaka cardiovascular maikaʻi loa.
7. Myocardial infarction ma ke ʻano hoʻopiʻi.
8. Hōʻeha ka puʻuwai paʻakikī e nā kaʻina hana kūpaʻa concomitant.

Hoʻomaopopo ʻia ka lāʻau lapaʻau ma ke ʻano he lāʻau lapaʻau e kuhikuhi ana i ka hoʻomākaukau ʻana i nā mea maʻi me ka hana ʻoi aku ka maikaʻi o ka hemodialysis.

Hiki ke kau ʻia ka lāʻau lapaʻau e like me ka mea o ka therapy paʻakikī e kuhikuhi ana i ka hoʻomākaukau ʻana i nā mea maʻi me ka hana ʻoi aku ka maikaʻi o ka hemodialysis.

Me ka mālama pono

Me ka nui o ka akahele, ua kuhikuhi ʻia ʻo Lorista i nā poʻe maʻi me nā maʻi maʻi e hiki mai ana:

• maʻi mellitus maʻiʻi
• ʻOiaʻiʻo
• nā maʻi maʻamau o ke koko,
• ka haʻalele ʻana o ke kaulike-wai-electrolyte i loko o ke kino,
• stenosis hāmeʻa like ʻole,
• kuʻe o ke kahe koko a me ka microcirculation,
• maʻi maʻi coronary artery
• huahua
• arrhythmia koʻikoʻi ma mua o ka hina o ka puʻuwai.

I kēia mau hihia a pau, ua kuhikuhi ʻia ka lāʻau lapaʻau ma nā liʻiliʻi liʻiliʻi, a ʻo ke keʻena mālama lāʻau e kūpono ana ma lalo o ka mākaʻi loea koʻikoʻi.

Pehea e lawe ai iā Lorista ND?

Hoʻolālā no ka hoʻohana kūloko. Hoʻopau ʻia nā papa ma hope o ka papaʻaina, holoi ʻia me ka wai piha nui. Koho ʻia ka pākēneka kiʻekiʻe e like me kahi kumuhana pākahi e noʻonoʻo ana i ke ʻano o ka makahiki maʻi a me ka maʻi i hōʻike ʻia me ia.

ʻAʻole pono ka nui o ka nui o ka lā ma mua o Lorista ma mua o 50 mg.

I kekahi mau manawa, hiki ke hoʻonui ʻia ka dosage e ke kauka i ka 100 mg o ka lāʻau lapaʻau i kēlā me kēia lā. ʻO ka lōʻihi maʻamau o ka lapaʻau mai nā wiki 3 a hiki i 1.5 mau mahina.

Hoʻopau ʻia nā papa ma hope o ka papaʻaina, holoi ʻia me ka wai piha nui.

Hoʻomaka ka mālamaʻana i nā meaʻuʻuku liʻiliʻi - mai 12-13 mg Lorista i kēlā me kēia lā. Ma hope o hoʻokahi pule, ua hoʻonui ʻia ka nui o ka lā i 25 mg. A laila e lawe ʻia nā papa i loko o kahi iniha o 50 mg.

Me ka hypertension arterial, hiki ke kaʻe o ka lā i kēlā me kēia lā 25 a hiki i 100 mg. I ka koho ʻana i nāosa nui, pono e mahele i kēlā me kēia lā i ʻelua pona. I ka wā o kahi papa mālama me ka nui o nā lāʻau lapaʻau diuretic, ua kuhikuhi ʻia ʻo Lorista i ka nui o 25 mg.

Hāʻawi ʻia kahi dosis hōʻemi no nā mea maʻi me ka hana hepatic impaired, pilikia ʻole.

Me ka maʻi diabetes

Hoʻomaka ka mālamaʻana me kahi waihona o 50 mg. Lawe ʻia nā papa he 1 manawa i ka lā. I ka wā e hiki mai ana, ua hoʻonui ʻia ka dosage i 80-100 mg, mālama ʻia i hoʻokahi manawa i ka lā.

Ma ka maʻi mellitus, hoʻomaka e hoʻomaʻamaʻa ʻia me kahi waihona ʻana o 50 mg.

ʻŌpala Gastrointestinal

• he ʻano hūnā
• ka pōʻai a me ke kūweʻe o ka luaʻi
• nā maʻi ʻino
• gaugitis
• ʻeha i ka ʻōpū.

Hiki i ka ʻike ʻO Lorista ke hoʻonāukiuki i nā hōʻeha o ka stool.

Pūnaehana pīhoihoi waena

Maʻa o ka ʻeha, ke kaumaha, nā luhi hiamoe, nāwaliwali, nā maʻi luhi o nā luhi, ka dizziness, hoʻemi i ka hiki ke hoʻomanaʻo i ka ʻike hou a me ka neʻe, a me ka hoʻopulapula o ka hoʻoweliweli.

Hiki i nā ʻeha o ke poʻo hōʻeha ke kau ʻana iā Lorista.

Hiki i ka lāʻau lapaʻau ke hoʻonāukiuki i ka hoʻomohala ʻana o nā maʻi kūlohelohe, i hōʻike ʻia ma ke ʻano o:

• rhinitis
• huhū
• ʻili ʻia ka ʻili e like me ka hives,
• kaʻiliʻili.

Nā ʻōlelo kikoʻī

Ma muli o ka hopena nui i ka pūnaehana neʻe i waena a me ka hoʻoluhi o ke kahe koko i ka wā o ka mālama ʻana, ʻoi aku ka maikaʻi o Lorista e pale ʻole i ka mālama ʻana i nā mīkini a me nā kaʻa.

I ka wā o ka mālama ʻana, ʻoi aku ka maikaʻi o Lorista e pale ʻole i nā mīkini a me nā kaʻa.

I ka wā o ka papa o ka therapeutic, ua manaʻo ʻia e nānā i nā pae kaloli o ke koko e pale ai i ka hoʻomohala ʻana o ka maʻi hypercalcemia.

Waihoia nā keiki Lorista ND

Ma muli o ka ʻike hemahema kumu o Lorista ma luna o ke kino o nā keiki, ʻaʻole hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā keiki ma lalo o nā makahiki he nui.

ʻAʻole hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā keiki ma lalo o nā makahiki he nui loa.

Hoʻohana i ka wā hāpai a me ka lactation

Ma muli o kāna hopena hopena, hiki i ka lāʻau lapaʻau ke hoʻopilikia i ka hoʻokumu ʻana o ka pūnaehana cardiovascular a me nā ʻolipo o ke kino o ka pūpū i ka wā o ka hoʻoulu ʻana i ka maʻi fetal, ka mea i hoʻopuni ʻia me ka make. Nui ka nui o ka pilikia i ka pūpū i mua o nā mea mua o ka ʻelua o ka hānau ʻana. No kēia kumu, ʻaʻohe hana o Lorista e mālama i nā wahine hāpai.

Mai hoʻohana i ka Lorista ma ka umauma. Inā pono, e hoʻokaʻawale iki i ka hoʻohana ʻana o kēia lāʻau antihypertensive e hoʻolako i ka ʻai kūlohelohe.

Ke noi no ka hana renal impaired

I ka hihia o ka hana ʻōlaʻi o ka pale a hōʻino i ka paʻakikī o ka hoʻololi, hoʻonā ʻia ka lāʻau lapaʻau ma nā ʻano maʻamau. Ma nā hihia koʻikoʻi nui loa, ʻo ka hoʻoholo ma ka hopena kiʻekiʻe a me ka hiki ʻana o ka pili ʻana iā Lorista i lawe ʻia e ke kauka.

I ka hihia o ka hana ʻōlaʻi o ka pale a hōʻino i ka paʻakikī o ka hoʻololi, hoʻonā ʻia ka lāʻau lapaʻau ma nā ʻano maʻamau.

Hoʻopili pū me nā lāʻau ʻē aʻe

Me ka hana like o Lorista me nā lāʻau antihypertensive ʻē aʻe, ua hoʻokō nei ka wikiwiki o ka wikiwiki a me ka maikaʻi o nā ʻōnaehana koko.

ʻO ka hui pū me nā antidepressants a me antipsychotics hiki ke hoʻowalewale i ka hoʻokumu ʻana o ka hoʻokō.

Hoʻopili maikaʻi nā Barbiturates a me nā glycosides cardiac me Lorista, ʻaʻole like i Rifampicin, e hōʻemi ana i ka hopena o kēia lāʻau. Hoʻopili ʻo Asparkam i kahi o Lorista, akā me ka hoʻohana like ʻana o kēia mau lāʻau, ua pono ka hoʻonui ʻia o ka pae o ka calcium.

Hoʻolaha ka waipuna

I ka wā o ka hoʻomehana, ua hoʻohālikelike ʻo Lorista i ka hoʻohana ʻana i nā mea inu ʻona. Hoʻonui ka Ethyl alkohol i ka hopena o ka mea maʻi e hoʻomohala i nā hōʻeha kino e like me ka hōʻeha ʻana a me nā hōʻeha.

I ka wā o ka hoʻomehana, ua hoʻohālikelike ʻo Lorista i ka hoʻohana ʻana i nā mea inu ʻona.

ʻO kahi mea nui no kēia lāʻau lapaʻau ʻo Lorista N. ʻO kēia mau lāʻau lapaʻau e hiki ke lilo i mea hou aku i ka losartan:

Ke waiho nei i nā kūlana no ka lāʻau lapaʻau

Hoʻokomo ʻia kēia lāʻau lapaʻau e mālama i kahi wahi pōʻeleʻele, ma kahi o ka hiki o nā keiki. ʻO ka mālama mālama wela a hiki i ka + 30 ° С.

Hoʻokomo ʻia kēia lāʻau lapaʻau e mālama i kahi wahi pōʻeleʻele, ma kahi o ka hiki o nā keiki.

Cardiologists

Valeria Nikitina, cardiologist, Moscow

ʻO ka hoʻohana ʻana o Lorista ND e hiki iā ʻoe ke pani i ka hoʻomohala ʻana o nā hoʻopiʻi weliweli ʻo nā pilikia o ka ʻōnaehana cardiovascular e like me ka hahau a me ka myocardial infarction. I nā ʻōkuhi i koho pololei ʻia, hoʻomanawanui maikaʻi ʻia ka lāʻau e nā mea maʻi me ka ʻole o ka hoʻomohala ʻana i nā hopena ʻaoʻao.

ʻO Valentin Kurtsev, ke kaukaʻi, cardiologist, Kazan

ʻO ka hoʻohana ʻana o Lorista he mea ākea ia ma ke kahua o ka cardiology. Ua hōʻike ʻia ka lāʻau lapaʻau a me nā hopena o nā hoʻokolohua lapaʻau i hoʻōla ʻia ka lāʻau lapaʻau i waena o nā poʻe maʻi me ka hōʻeha ʻana o ka puʻuwai naʻau a me ka hypertension.

Ua lanakila ka lāʻau lapaʻau i ka nui o nā loiloi maikaʻi loa mai nā mea maʻi a me nā kauka.

Nina Sabashuk, 35 makahiki, ʻo Moscow

Ua pilikia wau i ka piʻi koko nui no nā makahiki 10. Ma hope o ka loaʻa iaʻu o ka maʻi hypertension, lawe wau i nā lāʻau lapaʻau he nui, akā hoʻohana wale nō ʻo Lorista ND e ʻae iaʻu e hoʻopaʻa wikiwiki i koʻu ʻano a hoʻi i koʻu ola maʻamau i kekahi mau lā.

Nikolay Panasov, 56 makahiki, Eagle

ʻOkoʻa wau iā Lorista ND i mau makahiki. Lawe koke ka lāʻau i ke kaomi i ke ʻano maʻamau, hāʻawi i ka hopena diuretic maikaʻi. A ʻo ke kumukūʻai o ka lāʻau lapaʻau, kūpono hoʻi ia.

Alexander Panchikov, 47 makahiki, Yekaterinburg

ʻIke wau i ka hana naʻau me kahi papa maʻi. Me kahi exacerbation o ka maʻi, ʻōlelo ke kauka e lawe i nā papa no Lorista ND. Ua hauʻoli wau i nā hopena. ʻOiai me ka laulā ākea o nā hopena ʻaoʻao maikaʻi loa, ua hele maikaʻi mai kēia lāʻau lapaʻau.