Nā Papa - 1 papa:

ʻO ka papa hana neʻe: metformin hydrochloride 500 mg / 850 mg / 1000 mg,
Nā mea hoʻihoʻi: hypromellose 2208 5.0 mg / 8.5 mg / 10.0 mg, povidone K90 (collidone 90F) 20.0 mg / 34.0 mg / 40.0 mg, sodium stearyl fumarate 5.0 mg / 8, 5 mg / 10.0 mg
ʻO ka kiʻi kiʻiʻoniʻoni wai wai: hypromellose 2910 7.0 mg / 11.9 mg / 14.0 mg, polyethylene glycol 6000 (macrogol 6000) 0.9 mg / 1.53 mg / 1.8 mg, polysorbate 80 (ʻumikumamāwalu 80) 0, 1 mg / 0.17 mg / 0.2 mg, titanium dioxide 2.0 mg / 3.4 mg / 4.0 mg.

ʻO nā papa kiʻi ʻoniʻoni 500 mg, 850 mg, 1000 mg.

Hoʻopuka i ka lāʻau lapaʻau mua

Ma nā papa he 10 i loko o kahi pale polū blister mai kahi kiʻi o polyvinyl chloride a me kahi alumini foil i paʻi ʻia ua varnished.

No 15, 30, 60, 100, 120 papa i loko o kahi pahu poli i hana ʻia me ka polyethylene me kahi uhi i hoʻopaʻa ʻia me ka kaohi o ka wehe mua. Hoʻopiha ʻia ka wahi paʻa me ka lei lapaʻau. ʻO nā laka i hana ʻia i ka pepa a hōʻailona paha, a i ʻole nā mea polymeric i hoʻopili pono ʻia e hoʻopili ʻia ma nā waihona.

Hoʻopiha ʻaʻano pōkole lua

1, 2, 3, 4, 5, 6, 8, 9, or 10 mau pūʻulu blister, me nā kauoha no ka hoʻohana ʻana, ua waiho ʻia i loko o kahi pihi o ka pepa pahu no ka pale ʻana i ka mea kūʻai.

1 hiki i nā mea aʻoaʻo no ke hoʻohana ʻana i waiho ʻia i loko o kahi paʻi pepa no ka hoʻopiha ʻana i ka mea hoʻohana.

Nā papa ʻaina 1000 mg: nā kālani oblong biconvex i kāʻei ʻia me ke kāʻei kiʻi keʻokeʻo me ka pilikia o kekahi ʻaoʻao. Ma kahi ʻāpana ʻāpana, he keʻokeʻo a ʻokoʻa paha ke kumu.

ʻO kahi mākaʻi hypoglycemic o ka pūʻulu biguanide no ka hoʻohana waha.

Hoʻopuka a hoʻoili

Ma hope o ka lawelawe waha, ua hoʻohuihui ʻia ka metformin mai ka gastrointestinal tract maoli. ʻO ka bioavailability piha kūpono he 50-60%. Ka lōʻihi loa o ke kūkaʻi (Cmax) (ma kahi o 2 μg / ml a 15 μmol) i loko o ka plasma i hala ma hope o nā hola 2.5. Me ka hoʻohaʻina ʻana o ka meaʻai, ua hoʻemi ʻia ka haʻawina o ka metformin a kali.

Hoʻopuka koke ʻo Metformin i ka kiko, hoʻomaʻamaʻa ʻole ia i nā protein plasma.

Metabolism a me ka hoʻopā ʻana

Hoʻomili ʻia ia i kahi pae palupalu loa a hoʻopā ʻia e nā keiki. ʻO ka hoʻomaʻemaʻe i ke metformin i nā kumuhana olakino he 400 ml / min (4 mau manawa hou aku ma mua o ka clearance creatinine), e hōʻike ana i ka loaʻa o nā huna huna kanal. ʻO ka hapalua hapalua he 6,5 mau hola. Me ka hikiʻole o ka renal, ke hoʻonui nui ʻia, aia nō kahi pilikia o ka hōʻiliʻili o ka lāʻau.

Hoʻopau ka Metformin i ka hyperglycemia me ke alakaʻi ʻana i ka hoʻomohala ʻana o ka ha pilikia hypoglycemia. ʻAʻole e like me derivatives sulfonylurea, ʻaʻole ia e hoʻowalewale i ka huna ʻana o ka insulin a ʻaʻohe ona hypoglycemic hopena i nā poʻe olakino. Hoʻonui i ka paʻakikī o nā receptors peripheral i ka insulin a me ka hoʻohanaʻana i nā glucose i nā cell. Hoʻemi i ka hana glucose glucose ma ka pale ʻana i ka glucoseoneogenesis a me ka glycogenolysis. Hoʻopili i ka hoʻopili ʻana o ka pehu o ka glucose. Hoʻonohonoho ka Metformin i ka synthesis glycogen ma ka hana ʻana ma ka synthase glycogen. Hoʻonui i ka hiki o ka halihali i nā ʻano kīwili o nā membrane glucose. Eia kekahi, he hopena maikaʻi ia e pili ana i ka lipid metabolism: e hōʻemi ana i nā kiko o ka kolamu piha, ka lipoproteins haʻahaʻa haʻahaʻa a me nā triglycerides.

ʻOiai ke lawe nei i ka metformin, paʻa mau ke kino o ka mea maʻi i ka hoʻomau ʻana a i ʻole ka hoʻohaʻahaʻa ʻana. Ua hōʻike ʻia nā haʻawina hauoli ʻana i ka hopena o ka metformin no ka pale ʻana i ka maʻi maʻi i ka poʻe maʻi me ka prediabetes me nā mea pilikia hou aʻe no ka hoʻomohala ʻana i ka maʻi diabetes mellitus type 2, kahi i hiki ʻole ai i nā loli ke ola i ka hopena o ka glycemic kūpono e hoʻokō.

Nā Hōʻikeʻike Merifatin

ʻO ka maʻi diabetes mellitus type 2, keu i nā mea maʻi me ka momona, me ka hana ʻole o ka lāʻau ʻaina a me ka hana kino.

i nā pākeke, ma ka monotherapy a i hui pū ʻia me nā mea haole hypoglycemic waha a i ʻole paha me ka insulin.
i nā keiki mai 10 mau makahiki o ka monotherapy a i hui pū ʻia me ka insulin. ʻO ka pale ʻana i ka maʻi diabetes type 2 i nā mea maʻi me ka prediabetes me nā mea hou aku e pono ai no ka hoʻomohala ʻana i ke ʻano maʻi type 2, kahi i ʻae ʻole ai nā loli ola pono e loaʻa ai ka mālama glycemic kūpono.

Nā Hoʻolālā Merifatin

Hypersensitivity e metformin a i kekahi mea ʻokoʻa,
maʻi ketoacidosis maʻi, maʻi kanesa precoma, coma,
hana ʻole a hana ʻole a paʻa ʻole kahi māka (hana i hana ʻia ma lalo o 45 ml / min),
nā hopena ʻoi me ka pilikia o ka hoʻomohala ʻana i ka hana renal: dehydration (me ka maʻi ʻaʻa, ka luaʻi), nā maʻi koʻikoʻi o ka maʻi ʻeha, pīhoihoi,
nā hōʻike olakino i hōʻike ʻia aʻe o nā maʻi a me nā maʻi kūpaʻa e hiki ke alakaʻi i ka hoʻomohala ʻana o ka maʻi hypoxia (e pili ana i ka hina o ka naʻau, ke ake ʻole o ka naʻau me ka hemodynamics kūmau, ka huhū ʻole, ka huina myocardial infarction).
hoʻonui i ka hoʻokō a me nā trauma ke hōʻike ʻia nei ka maʻi insulin,
ake aho ole, ʻaole hema ʻole,
humuhinu maoli, huakino makehewa,
hapai
lactic acidosis (me ka mōʻaukala),
noi no ka liʻiliʻi ma mua o 48 mau hola ma mua a i loko o 48 mau hola ma hope o ka lawe ʻana i nā haʻawina radioisotope a i ʻole x-ray me ka hoʻomaka ʻana o ka iodine-medium vari,
ka mālama ʻana i kahi meaʻai hypocaloric (ʻoi aku ma mua o 1000 kcal / lā).

E hoʻohana me ka makaʻala o ka lāʻau lapaʻau:

i nā poʻe i ʻoi aku ma mua o ka 60 e hana i ka hana kino olakino, ka mea i hui ʻia me ka piʻi nui o ka hoʻomohala ʻana i ka waikena lactic,
i nā mea maʻi me ka maikaʻi ʻole (clearanine clearance 45-59 ml / min),
i ka wā hānai.

Merifatin Hoʻohana i ka wā hāpai a me nā keiki

ʻO ka maʻi mellitus maʻi maʻi ʻole i ka wā hāpai e pili ana i ka nui o ka nui o ka hānau hānau ʻana a me ka make ma mua. Hōʻike ka palena o nā ikepili e lawe i ka metformin i nā wahine hāpai ʻaʻole i hoʻonui i ka hopena o ka hoʻomohala ʻana i nā hemahema o ka hānau ʻana i nā keiki.

Ke hoʻolālā nei i ka hapai, me ka hoʻomaka ʻana o ka hapai ma ka hope o ka lawe ʻana i ka metformin me ka prediabetes a me nā maʻi type 2, pono e hoʻokaʻawale ʻia ka lāʻau lapaʻau, a inā i ʻano ke ʻano maʻi maʻamau, ua kau ʻia ka lāʻau lapaʻau. Pono e mālama i nā ʻike o ka glucose i loko o ke koko koko ma ke pae kokoke i ka maʻamau e hōʻemi i ka hopena o nā malalations fetal.

E hele a Metformin i ka waiū umauma. Hoʻokomo ʻia nā hopena i nā keiki hou i ka wā o ka wā o ka ʻōpū o ka wā e lawe ai i ka metformin i ʻike ʻole ʻia. Eia naʻe, ma muli o ka nui o ka waiwai o ka ʻikepili, ʻaʻole i ʻōlelo ʻia ka hoʻohana o ka lāʻau i ka wā o ka ʻōpū. ʻO ka hoʻoholo e pani i ka hōʻuluʻulu ʻana e pono e mālama i nā pono o ka umauma a me ka hiki o nā hopena kūpono i nā hopena kūpono i ka pēpē.

E hoʻokuʻu i ke ʻano, ka pūpū a me ka hoʻonohonoho

ʻO nā papaʻaina, i hoʻohui ʻia me ka poni keokeo keokeo, he oblong, biconvex, me ka loaʻa ʻana o ka ʻaoʻao ma kahi ʻaoʻao, i kahi mahele kea kahi o ka nui o ka waihoʻoluʻu a i ʻole keʻokeʻo.

1 kōpō
metformin hydrochloride	1000 mg

Nā mea kūʻai: hypromellose 2208 - 10 mg, povidone K90 (collidone 90F) - 40 mg, sodium stearyl fumarate - 10 mg.

ʻO ka kiʻi kiʻiʻoniʻoni wai wai: hypromellose 2910 - 14 mg, polyethylene glycol 6000 (macrogol 6000) - 1,8 mg, polysorbate 80 (ʻumikumamāwalu 80) - 0.2 mg, titanium dioxide - 4 mg.

10 kamepiula - nā kīpaha palemona (1) - nā ʻeke pepa.
10 kamepiula - nā ʻili uila (2) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (4) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (5) - nā ʻeke pepa.
10 kamepiula - nā papaki blister (6) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (7) - nā ʻeke pepa.
10 kamepiula - nā kīpaha blister (8) - nā ʻeke pepa.
10 kamepiula - nā ʻili uila (9) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (10) - nā ʻeke pepa.
15 ʻōpona. - nā kau (1) - nā ʻeke pepa.
30 kiʻi - nā kau (1) - nā ʻeke pepa.
60 pcs. - nā kau (1) - nā ʻeke pepa.
100 pcs - nā kau (1) - nā ʻeke pepa.
120 pcs - nā kau (1) - nā ʻeke pepa.

Ka hana lāʻau lapaʻau

ʻOiea hypoglycemic oral mai ka hui o ka biguanides (dimethylbiguanide). Hoʻopili ʻia ke ʻano hana o ka metformin me ka hiki iā ia ke kāpae i ka gluconeogenesis, me ka hoʻokumu ʻana i nā momona momona a me nā mea hoʻoneʻe o ka momona. Hoʻonui i ka paʻakikī o nā receptors peripheral i ka insulin a me ka hoʻohanaʻana i nā glucose i nā cell. ʻAʻole hoʻopilikia ka Metformin i ka nui o ka insulin i ke koko, akā hoʻololi i kona pharmacodynamics ma ka hoʻemi ʻana i ka ratio o ka lā i hoʻopaʻa ʻia ai ka insulin i ka manuahi a hoʻonui i ka pae o ka insulin i ka proinsulin.

Hoʻonohonoho ka Metformin i ka synthesis glycogen ma ka hana ʻana i ka synthetase glycogen. Hoʻonui i ka hiki o ka halihali i nā ʻano kīwili o nā membrane glucose. Hoʻopili i ka hoʻopili ʻana o ka pehu o ka glucose.

Hoʻēmi i ka pae o ka triglycerides, LDL, VLDL. Hoʻoulu ʻo Metformin i nā waiwai o fibrinolytic o ke koko ma o ke kāohi ʻana i kahi mea hoʻoneʻe i ka mea hoʻonāukiuki plasminogen.

ʻOiai ke lawe nei i ka metformin, paʻa mau ke kino o ka mea maʻi i ka hoʻomau ʻana a i ʻole ka hoʻohaʻahaʻa ʻana.

Lapaʻau lāʻau

Ma hope o ka lawelawe waha, ua hoʻopili mālie ʻia ka metformin a paʻa i ka hoʻopili ʻana mai ka ʻōpala. Loaʻa ka C max i ka plasma ma hope o nā hola he 2.5. Me kahi paona hoʻokahi o 500 mg, ʻo ka bioavailability kūleʻa he 50-60%. Me nā ingestion like ʻole, ua hoʻemi ʻia a emi aʻe ke ʻano o ka hoʻopili ʻana o ka metformin.

Hoʻolaha nui ʻia ka Metformin i ka hoʻopili kino o ke kino. ʻAʻole hiki ke hoʻopaʻaʻia i nā protein plasma. Hoʻomili ia i nā kuhi salivary, nā pēpē a me nā pōpoki.

I ka wā i hoʻoili ʻia ai nā keʻokeʻo. T 1/2 mai ka plasma he 2-6 hola.

I ka hihia o ka hana renal impaired, hiki i ka cumulation o metformin.

Hōʻikeʻike i nā lāʻau lapaʻau

ʻO ka maʻi diabetes mellitus type 2 (non-insulin-dependant) me ka papa ʻaina ʻana a me ka hana ʻana i ke kaumaha ole like ʻole, i nā mea maʻi me ka hoʻonāukiuki: i nā pākeke - ma ke ʻano monotherapy a i hui pū ʻia me nā ʻaihue hypoglycemic waha a i ʻole insulin, i nā keiki 10 mau makahiki a ʻoi aku - e like me monotherapy i ka hui me ka insulin.

Nā helu ICD-10

Aia ka helu ICD-10	Hōʻike ʻano
E11	ʻAno maʻi type 2

Ka hoʻoponopono ʻia ʻana

Lawe ʻia ʻia ma ke ʻano, ma ka manawa a ma hope o ka ʻai ʻana.

ʻO ka maʻi a me ke neʻe o ka hoʻokele e hilinaʻi ʻia ma ka ʻano kauka no ka hana.

Me ka monotherapy, ʻo ka maʻi pā hoʻokahi hoʻokahi no ka pākeke he 500 mg, ma muli o ke ʻano hana hoʻohālikelike i hoʻohana ʻia, ʻo 1-3 ka nui o ka lawelawe. Hiki ke hoʻohana i ka 850 mg 1-2 mau manawa / lā. Inā kūpono, hoʻonui pinepine ʻia ka pā me ka manawa o 1 pule. a i ka 2-3 g / lā.

Me ka monotherapy no nā keiki o 10 mau makahiki a ʻoi aku, ʻo ka ma mua mua he 500 mg a i ʻole 850 1 manawa / lā a i ʻole 500 mg 2 mau manawa / lā. Inā kūpono, me kahi huakaʻi o a ma kahi o ka 1 hebedoma, hiki ke hoʻonui ʻia ka nui i ka lōʻihi o 2 g / lā i nā lā 2-3.

Ma hope o nā lā 10-15, pono e hoʻoponopono ʻia ke kani e pili ana i nā hopena o ka hoʻoholo ʻana o ka glucose i loko o ke koko.

I ka hui pūʻana me ka insulin, ʻo ka hoʻomaka mua ʻana o ka metformin he 500-850 mg 2-3 mau manawa / lā. Koho ʻia ka nui o ka insulin e pili ana i nā hopena o ka hopena o ka glucose i ke koko.

Loaʻa ka hopena

Mai ka pūnaehana ʻana: hiki (maʻa mau ma ka hoʻomaka ʻana o ka mālama ʻana) ka kaila, ka luaʻi, ka ʻōpū ʻana o ke ahulau, ka lemulea, ka ʻike ʻana i ka ʻōpū ma loko o ka ʻōpū, i nā hihia kūwaho - he kue i ka hana o ka ate, hepatitis (nalo i hope ke kau ʻia ka mālama ʻana).

Mai ka ʻaoʻao o ka metabolism: loaʻa loa - ka lactic acidosis (wehe i ka mālama ʻia).

Mai ka ʻōnaehana hemopoietic: luhi pinepine loa - kahi kū ʻole i ka lawe ʻana i ka waiū B 12.

ʻO ka ʻōlelo ʻana o nā hana ʻino i nā keiki he 10 a ʻoi aku paha ka mea like ma ka pākeke.

E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana a me ka pōpoki

Hana ʻia ia i ke ʻano o nā papa kiʻi ʻoniʻoni kiʻi ʻia i loko o kahi iniha o metformin: 500 mg, 850 mg, 1000 mg.

Hoʻohui ʻia:

2208
sodium stearyl fumarate,
Povidone K90,
no ke uhi: hypromellose 2910,
titanium hone
hīmeni 80
polyethylene glycol 6000.

Hoʻopaʻa ʻia i loko o nā blisters o 10 mau ʻāpana, i kahi pūnana pahu mai 1 a 10 mau keleawe, a i ʻole i nā pahu pahu o nā 15, 30, 60, 100 a i ʻole nā papa 120.

Nā ʻōkuhi no ka hoʻohana (ʻano a me ke ʻano)

Lawe ʻia ʻo Merifatin ma ke ʻano a ma hope o ka ʻai. Koho ʻia ka ʻōkuhi ma ke kūlike i ka hōʻike a me nā pono maoli o ke kino.

Hoʻomaka ka lāʻauʻai ma kahi liʻiliʻi o 500 mg 1-3 mau manawa i ka lā. Inā pono, hiki iā ia ke hoʻonui mālie - i hoʻokahi manawa i kēlā me kēia 1-2 mau pule, i mea e pale aku ai i nā hopena maikaʻiʻole mai ka papa gastrointestinal. ʻO ka palena loa ʻo 2-3 g i kēlā me kēia lā.

No nā keiki, ʻo ka dosis mua ka 500 mg 1-2 mau manawa i ka lā. ʻO ka nui loa ka nui o ka 2 g i kēlā me kēia lā i kekahi mau pona.

I ka wā o ka lapaʻau me ka insulin, e pono ka nui o ka metformin o ke ʻano he 500-850 mg 2-3 mau lā i ka lā, a ua koho ʻia ka nui o ka hormone e pili ana i ka ʻikepili ʻike.

Nā hopena o ka lāʻau lapaʻau:

lactic acidosis,
nā hopena kūlohelohe
paila, mamaila,
pilikia pilikia
ʻākōwili ka naʻau i loko o ka waha
hua kalapalapalaoa o ka huahelu B12,
anemia
me ka hopena hui - hypoglycemia.

Ke keu

ʻOi paha ka hoʻomohala ʻana o ka acidact lactic i kumu ma ka hōʻemi o ka metformin i loko o ke kino. ʻO kāna mau hōʻailona kahi nausea, ka luaʻi, ka maʻi ʻeha, ka ʻōpū a me ka ʻehaʻeha o ka ʻōpū, ke ʻole ʻana o ka hanu, ke ʻano haʻahaʻa o ke kino, ke ʻano o ka ʻike ʻana i ka wī. Inā ʻike ʻia kēlā mau hōʻailona, pono e kāpae i ka lawe ʻana i ka lāʻau, hoʻomaha i ka mea maʻi a mālama i ka hemodialysis a me ka hoʻāʻo ʻana. He kūlana e ola nei kēia, ʻo ia no ka poʻe elemakule a me nā keiki, no laila he mea nui e ʻike i kāna mau hōʻailona.

Me ka hoʻohana pū ʻana me nā lāʻau lapaʻau e hoʻemi i ke kōpaʻa koko, hiki paha i ka hypoglycemia. Nā hōʻailonaʻeha: ka nāwaliwali, nā palau, ke kala, ka luaʻi, ka ʻike mua ʻole (ma mua o ka hāʻule ʻana o kahi coma), pōloli a me ka nui aʻe. Me kahi pepaʻoluʻolu, hiki i kahi mea ke hoʻomau i kona kūlana ma ka ʻai ʻana i nā meaʻai me nā momona. I ke ʻano hōʻona a me ke ʻano paʻakikī, koi ʻia kahi huakaʻi o ka momona glucagon a i ʻole ka hopena dextrose. A laila e lawe pono i ke kanaka i ka ʻike a laila hānai me ka meaʻai momona. He mea nui ia e nīnau aku ma hope i kahi loea no ka hoʻoponopono ʻana i ke ʻano o ka mālama ʻana.

Hoʻohui nūhou

Hoʻonui ʻia ka hopena o ka mālama ʻana me ka merifatin i:

nā mea āpau hypoglycemic āpau
mau poloka beta,
Nā NSAID
danazol
Nālailax
pili waiwai komo
luanuhauna
ʻO MAO a me ACE inhibitors,
huoli
ethanol.

Ua nāwaliwali ka hopena o ka metformin e:

Kiora
epinephrine
thiazide and loop diuretics,
kekahaka
ʻO nā hormones thyroid
haluluHalakalaha
nā mea hoʻohālikelike waha
humuhua's derivatives,
hoʻōla nicotinic.

Hoʻololi ʻo Cimetidine i ka hoʻopauʻana o ka metformin mai ke kino a hiki ke kumu i ka acidosis lactic.

Ua hoʻohua pono ʻo Merifatin iā ia ka hopena o nā derivatives Coumarin.

I ka koho ʻana i ka lāʻau lapaʻau me kēia mākēkē, pono ke ʻike i ke kauka komo i ka komo ʻana o nā mea i luna.

Nā ʻōlelo kikoʻī

I ka wā o ka mālamaʻana, he mea nui ia e nānā i ke kūlana o nā keiki. Ma kahi o kahi kānalua o ka ʻae ʻole o kā lākou hana, ke kāpae ʻia nei i kēia mea hana.

ʻAʻole ʻo Ka Metformin i hoʻopilikia i ka hiki ke lawe i kahi kaʻa, eia naʻe, i ka hui pū me ka insulin a i ʻole ka sulfonylurea, aia kahi hopena. No laila, me ka hoʻohui hoʻohui ʻana, pono ʻoe e hōʻole i ka lawe i kahi kaʻa a hana pū me nā hana paʻakikī.

Hiki i ke kīleʻa ke kumu i ka lactic acidosis, no laila lawe ʻia he mea pono ʻole.

I ka hoʻokuʻi ʻana o nā hana maʻi e hiki mai ana, i ka wā e mālama ai i nā maʻi hōʻeha, nā hōʻeha hōʻeha, nā exacerbations o nā maʻi maʻi, ʻaʻole i hoʻohana ʻia ka lāʻau lapaʻau.

Pono ka mea maʻi e ʻike i nā hōʻailona o ka hopena o ka hopena, hypoglycemia a me ka lactic acidosis a hiki iā ia ke hāʻawi i ke kōkua mua.

ʻAʻole loaʻa i nā pills nā carcinogens.

Nui! Hoʻokuʻu ʻia ka lāʻau lapaʻau ma o ka lāʻau wale nō!

Hōʻike ʻia i ke au kahiko

Hoʻohana ʻia nā papa hana Metformin i ka mālama ʻana o ka poʻe ʻelemakule, akā me ka akahele, no ka mea he ʻoi aʻe ka kiʻekiʻe o ka hoʻomohala ʻana i nā hypoglycemia a me ka lactic acidosis, ka mea i ka wā e hana ana i ka hana kino kaumaha. Pono kēia ʻōpiopio e nānā ākea e ka loea a me ka mālama mau ʻana i ke kūlana o nā keiki.

Nā kuleana a me nā kūlana e waiho ai

Pono e mālama ʻia ka lāʻau lapaʻau i kahi malū a maloʻo ka hiki ke mālama ʻia i nā keiki i ka mahana o ka lumi. ʻO ka wā i hoʻohana ʻia he 2 mau makahiki mai ka lā i hoʻopuka ai. A laila e hoʻohemo ʻia nā papa.

Loaʻa i kēia lako pahuhopu. He mea pono e hoʻomaʻamaʻa iā ʻoe iho iā lākou e hoʻohālikelike i nā waiwai a me ka hana pono.

Bagometua. ʻO kēia lāʻau lapaʻau ka hui pū ʻana, hoʻohui i nā mea ikaika o ka metformin a me ka glibenclamide. Hana ʻia e Chemist Montpellier, ʻAmelika. Uawe ia mai 160 rubles no ka paohi. Hoʻalōʻihi ka hopena o ka lāʻau. Hoʻohana kūpono ka bagomet i ka hoʻohana a loaʻa i loko o kahi lāʻau lapaʻau. Loaʻa iā ia nā contraindications maʻamau.

ʻO ka Hoʻonanea. ʻO kēia lāʻau lapaʻau, kahi mea e hui pū ai me nā metformin, e hana ʻia e ka hui ʻoʻāina ʻo Akrikhin. ʻO ke kumukūʻai no ka pauka mai nā 130 rubles (60 papa). He mea hoʻohālikelike maikaʻi kēia o nā lāʻau lapaʻau haole, akā ua palena ʻia i ka hoʻohana ʻana. No laila, ʻaʻole hiki ke hoʻohana ʻia ka glyformin e mālama i ke olakino o nā wahine hāpai, nā keiki a me nā mākua. Eia naʻe, ʻike maikaʻi kahi hopena maikaʻi ma ka mālamaʻana i ka maʻi maʻi ma ka laulā.

Metformin. ʻO ka lāʻau lapaʻau me ka pahuhopu mau. Nui nā mea hana: ʻo Gideona Richter, Hungary, Teva, Israel, Canonpharma a me Ozone, Rūsia. ʻO ke kumu kūʻai no ka ʻūpū ʻana i ka lāʻau lapaʻau he 120 rubles a keu aku. ʻO kēia ka analogue maʻalahi o Merifatin, kūpono a kūpono hoʻi.

Hoʻolaha. ʻO ia nā papa i loaʻa ka metformin. Mea hana - kamupene ʻo Merck Sante ma Farani. ʻO ke kumukūʻai o ka lāʻau lapaʻau he 130 rubles a keu aku. He ʻano mea hoʻohālikelike kēia o Merifatin, loaʻa no ke kūʻai aku a ma kahi uku hoʻi. Loaʻa ia i ka hopena wā pōkole a lōʻihi loa. ʻO nā maʻi nā maʻi maʻamau: ʻaʻole pono e hāʻawi ʻia i ka lāʻau lapaʻau i nā keiki, nā wahine hāpai a me ka pākeke. He maikaʻi nāʻike e pili ana i ka lāʻau lapaʻau.

Siofor. Hoʻopau ʻia kēia mau papa ma ka metformin. Mea hana - Kelemania ʻo Berlin Chemie a me Menarini. ʻO ke kumu kūʻai o ka pauka he 200 mau rubles. Loaʻa ma nā makemake a i ke kauoha. Hana ʻia kāna hana i ka manawa, hiki ke hoʻohana pū ʻia me nā lāʻau lapaʻau ʻē aʻe. ʻO ka papa inoa o contraindications he maʻamau.

Metfogamma. ʻO ka hana ikaika e like me ka merifatin. Hana ʻia e Werwag Pharm, Kelemānia. Aia nā papa mai 200 rubles. Hoʻohālike ka hana, me nā pāpā ma luna o ka hoʻohana ʻana. ʻO kahi koho ʻē aʻe maikaʻi a kūpono hoʻi.

Hoʻolohe Ke lawe ʻia nei ka loli mai kekahi a i ke ʻano lāʻau hypoglycemic ʻē aʻe ma lalo o ka mākaʻikaʻi ʻana o kekahi kauka. Ua papa ʻia ka lāʻau lapaʻau pilikino!

ʻO ka maikaʻi loa nā loiloi o ka merifatin. ʻO ka hana kūpono, ka mākaukau e lawe me nā lāʻau lapaʻau ʻē aʻe. Aʻo nā hopena hopena, kākau ka mea maʻi ma ka hoʻomaka ʻana o ke ʻano maʻi, ʻoiai ke ʻano ka hana o ke kino i ka lāʻau. No kekahi, ʻaʻole kūpono ka hoʻoponopono.

Olga: "ʻO wau kahi maʻi maʻi i ka maʻi maʻi. Ua mālama lōʻihi wau iā ia, ʻo ka mea nui me nā lāʻau lapaʻau me ka metformin i ka ʻano. Ua hana hou au iā Merifatin ma ke ʻōlelo a kuʻu kauka. Makemake wau i kona hopena mau loa. ʻAʻole hōʻoluʻolu ka maikaʻi. A ma ka hale ʻaina kala mau ʻo ia nō. No laila he mea hana maikaʻi. ”

Valery: “Maʻalahi au i ka maʻi diabetes ma ka momona. ʻO nā mea āu i hoʻāʻo ai, ua kōkua ʻole keʻai. Ua kuhikuhi ke kauka i ke Merifatin, he mea pono ke kōkua hōʻemi i ke kaupaona. A ua kūpono kona. ʻAʻole wau e mālama mau i ke kō i kēia manawa, akā ua nalowale wau i ʻekolu kilokilo i hoʻokahi mahina. Noʻu, he holomua kēia. No laila ke kuhikuhi aku nei au iā ia. "

Pākuʻi helu

oblong biconvex papa, keʻokeʻo kāʻei kiʻiʻoniʻoni me ka pilikia ma kekahi ʻaoʻao. Ma kahi ʻāpana ʻāpana, he keʻokeʻo a ʻokoʻa paha ke kumu.

Pākaukau 1 papa:

ʻO kēia papa hana: metformin hydrochloride 1000 mg.

Nā mea kū'ē: hypromellose 2208 10.0 mg, povidone K90 (collidone 90F) 40.0 mg, sodium stearyl fumarate 10.0 mg.

ʻO ka kiʻi kiʻiʻoniʻoni wai wai: hypromellose 2910 14.0 mg, polyethylene glycol 6000 (macrogol 6000) 1.8 mg, polysorbate 80 (ʻumikumamāwalu 80) 0.2 mg, titanium dioxide 4.0 mg.

Lapaʻau lāʻau

Nā hopena hopena

Ka hopena o ka hopena o ka hopena o ka lāʻau lapaʻau e like me ka manawa: pinepine pinepine (≥1 / 10), pinepine pinepine (≥1 / 100, 35 kg / m2,

- he mōʻaukala o ka maʻi maʻi gestational,

- he moʻolelo ʻohana no ka maʻi maʻamau i nā hoahānau o ka papa mua,

- hoʻonui paʻa o ka triglycerides,

- ka hōʻemi iki ʻana o ka HDL cholesterol,

Hoʻopilikia i ka hiki ke pana i nā kaʻa a me nā mīkini:

ʻAʻole ke kumu o ka monotherapy i ka metformin i ka hypoglycemia a no laila ʻaʻole i pili i ka hiki ke lawe i nā kaʻa a me nā hanaʻenehana. Eia nō naʻe e pono e mālama ʻia nā mea maʻi e pili ana i ka hiki ʻana o ka hypoglycemia i ka wā e hoʻohana ai i ka metformin i hui pū me nā lāʻau lapaʻaka hypoglycemic (sulfonylurea derivatives, insulin, repaglinide, etc.).

ʻO ka maʻi diabetes mellitus type 2, keu i nā mea maʻi me ka momona, me ka hana ʻole o ka lāʻau ʻaina a me ka hana kino.

- i nā poʻe pākeke, e like me monotherapy a i hui pū ʻia me nā mea kū a waha hypoglycemic a i ʻole i ka insulin,

- i nā keiki mai 10 mau makahiki o ka monotherapy a i ʻole pū me ka insulin. ʻO ka pale ʻana i ka maʻi diabetes type 2 i nā mea maʻi me ka prediabetes me nā mea hou aku e pono ai no ka hoʻomohala ʻana i ke ʻano maʻi type 2, kahi i ʻae ʻole ai nā loli ola pono e loaʻa ai ka mālama glycemic kūpono.

Ke kinikini Merifatin: ʻōkuhi no ka hoʻohana

E hoʻolaʻa i ka pae o ka glucose i ke koko, ua hoʻohana ʻia nā ʻano lāʻau like ʻole, kahi i loaʻa ʻo Merifatin. ʻO ka lāʻau lapaʻau Hypoglycemic he contraindications a me nā hopena ʻaoʻao, no laila ma mua o ka hoʻomaka ʻana o ka mālama ʻana, pono ʻoe e kipa i ka loea a hoʻopaʻa i nā ʻōlelo kuhikuhi.

E hoʻokuʻu i nā palapala a me ka ʻano

Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa o 500 mg, 850 mg a me 1000 mg, coated. Ua kau ʻia lākou ma 10 mau ʻāpana. i loko o kahi poho. Aia ka mea i hoʻopili ʻia ai ka pahu kākela 1, 2, 3, 4, 5, 6, 8, 9, a i ʻole 10 mau palaha. Hiki ke kau i nā papa i loko o kahi pahu pololi o 15 mau pcs., 30 pcs., 60 pcs., 100 pcs. a i ʻole 120 pcs. ʻO ka mea kūpono i ka metformin hydrochloride. ʻO nā mea kōkua i ka povidone, hypromellose a me ka sodium stearyl fumarate. Kūkulu ʻia i ka film film soluble polyethylene glycol, titanium dioxide, hypromellose a me polysorbate 80.

Me ka mālama pono

Hoʻohana maikaʻi lākou i ka lāʻau lapaʻau i ka wā o ka hana o ka hōʻeha ʻana a me nā hōʻeha inā pono ke lawe i ka insulin, ka hapai, ka ʻokiʻoki ʻana a i ʻole ke ʻano ʻawaʻawa ʻawaʻawa, e pili ana i ka meaʻai haʻahaʻa, ʻoniʻoni lactic, a me ka wā ma hope o ka wā ma hope o ka radioisotope a i ʻole x-ray hoʻokolohua, i ka wā e lawelawe ʻia ai ka manawaleʻa iodine i loko o ka mea maʻi . ^ E Ha yM.

Ma ka wā hāpai, pono ke mālama ʻia ʻo Merifatin.

Pehea e lawe ai iā Merifatin?

Pono ka huahana no ka hoʻohana ʻana ma ka waha. ʻO ka dosage mua i ka wā monotherapy i nā maʻi maʻi ʻo 500 mg 1-3 mau manawa i ka lā. Hiki ke hoʻololi ʻia ka hopena i 850 mg 1-2 mau manawa i ka lā. Inā lawa, hoʻonui ʻia ka pā i ka 3000 mg no nā lā 7.

Manaʻo nā keiki ma mua o 10 mau makahiki e lawe i ka 500 mg a i ka 850 mg hoʻokahi i ka lā a i ʻole 500 mg 2 mau manawa i ka lā. Hiki ke hoʻonui i ka dosage i loko o ka hebedoma a 2 g i ka lā no 2-3 mau pona. Ma hope o nā lā 14, e hoʻoponopono ke kauka i ka nui o ka lāʻau lapaʻau, me ka mālama ʻana i ka nui o ke kō i loko o ke koko.

Ke hui pū me ka insulin, ʻo ka maʻi o Merifatin he 500-850 mg 2-3 mau manawa i ka lā.

ʻŌpala Gastrointestinal

Mai ka ʻaoʻao o ka hāhai ʻana, ka nausea, ka luaʻi, ka maʻi ʻeha, ka ʻeha ʻeha a me ka nele o ka makemake e mālama ʻia. ʻO nā hōʻailona kūpono ʻole e kū pono ma ke kahua mua o ka mālama ʻana a haʻalele i ka wā e hiki mai ana. I ʻole e hoʻoulu pū me lākou, pono e hoʻomaka me kahi pae hōʻemi haʻahaʻa a hoʻonui iā ia.

Hoʻopili pū me nā lāʻau ʻē aʻe

Pāpā ʻia ka hoʻohui ʻana i ka metformin me nā lāʻau lapaʻau i ka iodine. Me ka makaʻala, lawe lākou i ka Merifatin me Danazole, Chlorpromazine, glucocorticosteroids, diuretics, injectable beta2-adrenergic agonists a me nā mea antihypertensive, koe wale no ka mea pale aku o ka agiotensin e hoʻohuli ana i ka enzyme.

Hoʻonui ʻia ka hoʻonui ʻana o ka metformin i ke koko i ka manawa o ka launa pū me nā lāʻau cationic, ma waena o amiloride. Hoʻonui ka hoʻonui ʻia o ka metformin i ka wā e hui pū me ka nifedipine. Hoʻopilikia ka contraceptives Hālal i ka hopena hypoglycemic o ka lāʻau.