Pehea e hoʻohana ai iā Metglib?

Pono e pili ana i ka maʻi diabetes "Pehea e hoʻohana ai i ka Metglib Force?

ʻO ka Metglib Force e pili ana i nā mea hana hypoglycemic. Hoʻolauna ka hana maʻamau o ka nui o ka glucose koko. He hopena hoʻomanawanui nō. Hoʻohana ʻia e mālama i ka maʻi maʻi type 2.

E hoʻokuʻu i nā palapala a me ka ʻano

Loaʻa ka lāʻau lapaʻau ma ke ʻano o nā papa i ka maʻi he 2.5 mg + 500 mg a me 5 mg + 500 mg. ʻO nā mea nui, he glibenclamide a me metformin hydrochloride. Hōʻike ʻia nā mea i koe: ke kō, kalima dihydrate, a me ka macrogol a me ka povidone, kahi liʻiliʻi o ka cellulose.

ʻO ke kiʻi o nā papa ʻaina keʻokeʻo ʻōwili 5 mg + 500 mg i loaʻa i ka Opadra keʻokeʻo, giprolose, talc, titanium dioxide. Aia nā papa ʻāpana i ka laina hoʻokaʻawale.

Nā Papa 2.5,5 + 500 mg oval, i uhi ʻia me ka pale pale kiʻi me kahi kala hoʻoneʻe.

Ka hana lāʻau lapaʻau

ʻO ia kahi mea hoʻohui hypoglycemic agent, kahi sulfonylurea derivative o 2 mau hanauna, i manaʻo ʻia no ka lawelawe waha. Loaʻa ia i nā hopena pancreatic a me nā extrapancreatic hopena.

Hoʻokumu ʻo Glibenclamide i ka mea huna o ka insulin ma ka hoʻoli ʻana ʻana i kona ʻike ʻana e nā pū beta i nā pancreas. Ma muli o ke hoʻonuiʻana i ka hoʻohuiʻana o ka insulin, e hoʻopaʻa ana i ka huli ʻana i nā selela i ka wikiwiki. Ke iho nei ke kaʻina o lipolysis o ka adipose kiko.

Loaʻa ka pae plasma kiʻekiʻe loa ma hope o 2 mau hola ma hope o ka lawe ʻana i ka ʻaʻe. ʻO ka hapalua hapalua o nā glibenclamide e lōʻihi ka lōʻihi ma mua o ka metformin (ma kahi o 24 mau hola).

Nā hōʻailona no ka hoʻohana ʻana

ʻO nā ʻōhua no ka hoʻohana ʻana i nā maʻi kauka ma lalo iho nei:

• ʻano laikē type 2 i ka pākeke, inā ʻaʻole kōkua ka ʻaʻaʻai a me ka hoʻomaʻamaʻa.
• ka nele o ka hoʻohana pono ʻana o ka mālama ʻana me nā derivatives o ka olony a me ka metformin,
• e hoʻololi i ka monotherapy me nā 2 lapaʻau i nā kānaka me ka mana glycemic maikaʻi.

Hoʻohana ʻia ka lāʻau lapaʻau no ka maʻi maʻi type 2 i nā pākeke, inā ʻaʻole kōkua ke ʻano a me ka hoʻoikaika kino.

Nā Hoʻohui

Nui kekahi contraindications i ka hoʻohana ʻana i kēia lāʻau lapaʻau i wehewehe ʻia i nā ʻōlelo aʻoaʻo. I waena o lākou:

• hypersensitivity i nā māhele o ka lāʻau lapaʻau,
• maʻi diabetes type 1
• hana koʻikoʻi nā keiki,
• maʻi maʻamau ketoacidosis,
• nā hopenaʻeha e hele pū me ka hypoxia kiko,
• hapai a lactation
• nā maʻi ʻohi
• nā hōʻeha a me nā hana lehulehu,
• con conidance con miconazole,
• make wai make,
• lactic acidosis,
• ka hana ʻana i kahi meaʻai haʻahaʻa,
• keiki malalo o 18 makahiki.

Me ka mālama nui, ʻōkuhi kēia lāʻau lapaʻau no ka poʻe e loaʻa ana i ka maʻi febrile, inu waiʻona, hana adrenal impaired, gland pituitary a me nā gland thyroid. Ua kuhikuhi pono ʻia i nā poʻe he 45 mau makahiki a ʻoi aku paha (ma muli o ka nui o ka ulu o ka hypoglycemia a me ka lactic acidosis).

Pehea e lawe ai i ka Metglib Force?

Pau nā papa ʻōlelo no ka hoʻohana ʻana i ka waha. Koho ʻia ka ʻākāka hoʻokahi, me ka mālama ʻana i ka nui o ka hōʻeha o nā hōʻike lapaʻau.

Hoʻomaka me 1 papa i kēlā me kēia lā me nā inika o nā mea ikaika o 2.5 mg a me 500 mg, kahi. Hoʻonui i ka nui o ka waiʻai i kēlā me kēia pule, akā hāʻawi ʻia i ka nui o ka glycemia. Me ka hui pū ʻana e hoʻohālikelike ai, ʻoiai inā ʻo ia ka mea i hoʻokaʻawale ʻia e ka metformin a me nā glibenclamide, pono ʻia e inu i 2 papa i kēlā me kēia lā. ʻO ka ʻae loa ʻana i kēlā me kēia lā e ʻānai ʻia ʻoi aku ka 4 mau papa i ka lā.

Nā hopena hopena

I ka wā mālama, hiki ke hoʻomohala ʻia ka loaʻa ʻana o kēlā ʻano hopena.

• leuko- a me thrombocytopenia,
• anemia
• anaphylactic haʻalulu,
• huahuʻi,
• lactic acidosis,
• kaomi ʻana i ke kō o ka vitamin B12,
• nā kuhi hewa
• ua hoemi i ka hihio
• ninini
• utuka
• nā ninia
• nele i ka momona
• he ʻeha o loko o ka ʻōpū
• lawelawe aho ʻaia,
• repatitis react
• nā hopena ʻili
• urticaria
• ʻūkū pū i hui pū ʻia e ka minamina
• erythema
• dermatitis
• ka hoʻonui ʻana o ka urea a me ka hana i loko o ke koko.

Pono e hoʻomaopopo ʻia ka poʻe e pili ana i ka hiki ʻana o ka hypoglycemia a hana i nā hana e pale ai ma mua o ka hoʻi ʻana aku ma hope o ka huila o ke kaʻa a i ʻole e hoʻomaka ana e hana me nā hana paʻakikī e koi nui ai ka naʻau o ka makaʻala.

Nā ʻōlelo kikoʻī

Hoʻopili ʻia ka lāʻau lapaʻau i ka mālama ʻana i nā wela palupalu, nā maʻi maʻi pāpaʻomaʻi, nā mākaukau paʻakikī ma mua o nā maʻi nui. I ia mau kūlana, huli lākou i ka insulin maʻamau. Hōʻalo ka pilikia o ka hoʻomohala ʻana i ka hypoglycemia me nā abnormalities i ka meaʻai, ʻaina lōʻihi a me nā NSAID.

ʻAʻole i ʻae ʻia. Loaʻa ka mea hana a ka pale i ka pale o ka plasenta a hiki i ka hana ʻino ke hana i ke kaʻina hana.

ʻAʻole hiki iā ʻoe ke lawe i nā paila i ka wā lactation, no ka mea nā mea ikaika e hele i loko o ka waiū. Inā makemake ʻia ka lāʻau lapaʻau, ʻoi aku ka maikaʻi o ka haʻalele i ka umauma.

ʻAʻole pili i nā maʻi pediatrics.

Pono e mālama nā kāne a me nā wahine ma mua o 65 i kēlā mau kānaka, e hoʻonui nui ʻia ka pilikia o ka hoʻomohala ʻana i ka hypoglycemia.

Hoʻohui ʻia ka hiki ke hoʻohana ʻia e nā mahele cleinine. ʻOi aku ke kiʻekiʻe, ua kuhikuhi ʻia ka lāʻau liʻiliʻi. Inā ʻinoʻino ke ʻano o ka mea maʻi, ʻoi aku ka maikaʻi o ka hōʻole ʻana i ia ʻano mālama.

ʻAʻole loaʻa ka ʻae ʻia inā ʻike ʻia ka puʻuwai koʻikoʻi. Hoʻopili kēia i nā mea hoʻoikaika paʻa i ka ate a hāʻawi i ka hoʻohena ʻana i nā hoʻokolohua hana ʻoi aku.

Ke keu

Me kahi overdose, kū ʻia ka hypoglycemia. Hiki ke hoʻoponopono ʻia kahi pae mālie e ka hoʻohana koke ʻana i ke kō a me nā meaʻai i loaʻa i ka haʻalulu. Lā ʻoe i maʻaneʻi a i ʻole ka hoʻoponopono ʻana i ka meaʻai.

I nā hihia koʻikoʻi, ka hele pū ʻana me kahi kūlana ʻole ʻike, hoʻomanaki i ka maʻi a i ʻole coma mea hōʻeha, he hopena glucose a i ʻole ka intramuscularly glucagon e lawelawe ʻia ana. Ma hope o kēia, ua pono e hānai i kahi mea ʻai i kahi mea momona a me nā mea momona wikiwiki.

I ka poʻe maʻi me ka maʻi hepatic, ʻoi ka hoʻomaʻamaʻa ʻana o ka glibenclamide. ʻAʻole hōʻino ʻia ka lāʻau lapaʻau e nā dialysis, no ka mea Hoʻopili maikaʻi nā glibenclamide i nā protein koko.

Hana ʻia kahi overdose wale nō ma ka hoʻonohonoho o kahi haukapila, i ka hiki ʻana i ka acidosis lactic. ʻO ka meaʻoi loa i kēia hihia ʻo hemodialysis.

Hoʻopili pū me nā lāʻau ʻē aʻe

ʻO ka hoʻohana pūʻana o ka miconazole, hoʻonui i ka fluconazole ka hopena o ka hypoglycemia. Hoʻopili ʻo Phenylbutazone i ka paa ʻana o ka waiwai ikaika i nā kāpena protein, ke alakaʻi nei i ka hypoglycemia a me kā lākou hōʻiliʻili i ka serum koko.

ʻO nā lāʻau lapaʻau me ka ʻike iodine i hoʻohana ʻia i ka diagnostics X-ray e hoʻopau pinepine i ka hana o ke keiki a me ka metformin cumulation. Hoʻ hoʻonāukiuki kēia i ka loaʻa o ka acidosis lactic.

Hoʻokomo ʻo Ethanol i nā hopena like ʻole disulfiram. Hoʻemi ka diuretics i ka hopena o ka hopena o ka lāʻau. ACE inhibitors a me beta-blockers alakaʻi i kahi kūlana hypoglycemic.

Mai lawe i kahi papa peni me ka waiʻona. Hoʻopilikia kēia i nā hypoglycemia koʻikoʻi, hoʻonui i nā hopena ʻē aʻe.

Aia kekahi papa inoa o nā hoʻohālikelike o kēia lāʻau lapaʻau, e like me ia i nā mea hoʻoikaika a me ka hopena.

• ʻO Aōmomi
• Hoʻohanohano
• Glibomet,
• ʻOlauwa,
• Makalei,
• Huakai Hou,
• Metglib.

Nā Hōʻikeʻike e pili ana i ka Pūnaewele Metglib

Moroz V. A., 38 makahiki, endocrinologist, Arkhangelsk: "He maikaʻi ka lāʻau lapaʻau. ʻĀnō wau e hoʻāʻo e koho iā ia i nā manawa pinepine. Mālama maikaʻi ka Sugar i nā maʻi maʻi maʻa, ʻaʻohe hana like ʻole. "

Kozerod A.I., 50 makahiki, endocrinologist, Novosibirsk: "Makemake wau i kēia lāʻau lapaʻau, ʻae maikaʻi ʻia e nā maʻi. He kuhikuhi pinepine wau iā ia, akā ma mua o ka hana ke ʻike nei iaʻu e ʻike i loko o ia mau wahi lapaʻau i loaʻa ai. "

Veronika, 32 makahiki, Moscow: "Ua maʻi koʻu makuahine i ka maʻi maʻamau. I ka wā mua, ua mālama ʻia ʻo ia me Glybomet. Akā i ka manawa e koi ai ka hoʻonui ʻana i ke ʻano, ua lilo ia he mea uku nui loa. Ua hoʻololi ʻia ka glibomet e ka Metglib Force, ʻo ia ka hapa o ka hapalua. ʻO ka lāʻau lapaʻau ka hana maikaʻi loa, ʻoiai me kaʻole o ka meaʻai. Mālama ʻia ka Sugar i kahi pae ua lōʻihi ʻole ka hypoglycemia. ʻO nā mea maikaʻi wale nō ke paʻakikī i ka ʻike ʻana i ka mākeke. ”

ʻO Roma, 49 makahiki, ʻo Yaroslavl: “I ka pae ʻana o koʻu kōʻai gula i ka 30 a ua manaʻo koke ʻole au e hele i ka haukapila, ua loaʻa iaʻu kahi maʻi diabetes. Ua hoʻomaka lākou i ka terapi insulin. A laila hoʻomaka wau e kāhāhā me ke kauka inā hiki paha ke hoʻololi mai nā ʻokiʻō ʻana i nā papa. Ua ʻōlelo aku ke kauka e hoʻāʻo ana i nā papa papa ʻo Metglib. Ua hoʻohana au iā ia no nā makahiki 2, ua hauʻoli wau. Mālama mau ʻia ka Sugar i ka pae, ʻaʻohe hewa no kekahi manawa lōʻihi. ”

ʻO Valeria, he 51 makahiki o Chelyabinsk: “Ua inu au i ka lāʻau lapaʻau ma kahi o hoʻokahi makahiki. He maʻamau ke gula, ʻaʻohe ʻano o ka hypoglycemia, akā ua manaʻo wau ʻaʻole pono, aia mau. Ka mea i loaʻa iaʻu he pilikia me ke kūpaʻa thyroid. I kēia manawa ua koho mākou i ka lāʻau kūpono. Ua haʻalele ke kauka i nā papa o ka Pūnaewele ʻo Metglib. Ke hana maikaʻi nei ʻo ia.

ʻO nā huahana Pharmacological o ka lāʻau Glibomet

Lapaʻau lāʻau ʻO Glibomet kahi hui pū me ka glibenclamide a me ka metformin. ʻO ka hopena hui pū ʻana o nā ʻāpana ʻelua, ʻo ka hoʻoulu ʻia ʻana o ka huna ʻana o ka insulin endogenous i kumu ʻia e ka glibenclamide, a me ka nui o ka hoʻonui ʻana i ka hoʻohana ʻana o ka puhipuhi e nā kikoʻī ma muli o ka hana a ka metformin. Ke alakaʻi nei kēia i kahi hopena synergistic nui, hiki iā ia ke hōʻemi i ka nui o nā mea āpau o ka lāʻau, no laila e hōʻemi nei i ka hoʻouluʻana o ka pancreatic cells-cells a me ka pilikia o ka hoʻomohala ʻana i kā lākou hana hana, e hōʻemi nui i ka hopena o nā hopena ʻaoʻao.
Lapaʻau lāʻau Ma kahi o 84% o glibenclamide e hoʻopili ʻia i ka digestive tract. Hoʻomaumi ia i ka puʻuwai me ka hoʻokumu ʻana o nā metabolites kaohi, i hoʻopā ʻia i nā feces a me ka urine. ʻO ka hapalua kahi ola he mau hola 5. ʻO ke kiʻekiʻe o ka pilina o ka protein protein he 97%.
ʻO ka Metformin, hoʻolaha ʻia i loko o ka pānaehana hana, ka wikiwiki i ka leʻa a me ka urine, ʻaʻole paʻa i nā protein plasma, ʻaʻole i hana ʻia i loko o ke kino. ʻO ka hoʻopau hapa-hapalua ke ola ma kahi o 2 mau hola.

ʻO ka hoʻohana nuiʻana o ka lālani Glibomet

Hoʻololi ka lāʻau i kēlā me kēia lā a me ka lōʻihi o ka lāʻau lapaʻau e kēlā me kēia kauka e like me ke kūlana metabolic o ka mea maʻi. ʻO ka maʻa mua no ka pākeke ka maʻa mau 2 papa i kēlā me kēia lā (e lawe i 1 papa i ke kakahiaka a me ke ahiahi me nā meaʻai), ʻaʻole e hoʻonui ka lāʻau o kēlā me kēia lā i nā papa 6 (2 papa 3 mau manawa i ka lā me nā meaʻai). Hāʻawi i ka palena liʻiliʻi maʻa mau, e hāʻawi ana i ka mana kūpono o ka pae o ka glycemia. Hiki ke loli iki ka wai i kēlā me kēia lā a hiki i ka palena liʻiliʻi e lawa ai ka mālama ʻana i ke kō o ka glucose koko.

Nā hopena ʻaoʻao o ka lāʻau lapaʻau Glibomet

Ma nā hanana maʻamau, hiki i ka hoʻomohala ʻana o ka hypoglycemia, ʻoi aku paha i nā mea maʻi debilitated, ka poʻeʻelemakule, me nā hana ʻano maʻamau, me ka ʻai ʻawaʻawa a i ʻole e inu ʻana i ka wai, inā i nā mea maʻi āpau a me / a hana ʻole paha ka lolo. I kekahi manawa aia kahi hōʻea, ka pilikia o ka gastrointestinal: nausea, anorexia, gastralgia, luaʻi, ʻeha, koi aku i ka hoʻokuʻu ʻana o ka mālama ʻana. Kūʻai kekahi, e ulu ka hopena o ka ʻili-aila i ka maʻi maʻamau, maʻa mau lākou i ka wā pōkole a nalo ke hele ʻana me ka mālama hoʻomau. ʻO nā hihia i hōʻike ʻia i loko o nā palapala paʻi o ka hiki ke hoʻomohala ʻia o ka metabolic acidosis i ka wā ʻo ka metformin ka luhi. Eia nō naʻe, ua hōʻike maoli ʻia i loko o nā mea maʻi me nā mea pilikia, e like me ka renal a me ka cardiovascular failed, hiki i kēia ʻano ke hana i ka maʻi koʻikoʻi inā ʻaʻole e hoʻokuʻu koke ʻia ka lāʻau lapaʻau a ʻaʻole lawe ʻia nā lāʻau lapaʻau kūpono. ʻO nā ala o ka hoʻonui ʻana i ka nui o ka waikaʻi lactic i loko o ka serum o ke koko, ke piʻi ʻana me ka nui o ka ʻoihana o ka lactate / pyruvate, ua hōʻike ʻia kahi emi ʻana i ka pH koko a me ka hyperazotemia (ua hōʻike ʻia nā hihia āpau no nā mea maʻi me kahi papa maikaʻi ʻole o ka maʻi maʻamau). ʻO ka hoʻomohalaʻana i ka hoʻoliʻume metabola hiki ke alakaʻi i ka hoʻohana pinepine ʻana i ka waiʻai i ka wā e mālama ai me ka lāʻau lapaʻau. He ʻokoʻa loa ka Hematopoiesis a nānā pinepine ia mea.

Nā hua'ōlelo lāʻau Glibomet

ʻO ka hopena hypoglycemic of glibenclamide ka potentiated e dicumarol and its derivatives, MAO inhibitors, sulfonamide drug, phenylbutazone and derivatives, chloramphenicol, cyclophosphamide, probenecid, pheniramine, salicylates, miconazole no ka hoʻoponopono waha, sulfinpyrazone, kiʻekiʻe wai wai. Hiki ke hoʻonāukiuki i ka hopena o ka glibenclamide me ka hoʻohana pinepine ʻana o ka epinephrine, corticosteroids, contraceptives oral, diia at thiazide diuretics a me barbiturates. Pono e mālama pono i ka wā e hoʻohana ana i nā ʻae ʻenehana me ors-adrenergic me nā mea blockers. Pono e hāpai ʻia i hiki i ka biguanides ke hoʻonui i ka hopena o nā anticoagulants.

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

Lawe ʻia ka lāʻau lāʻau me ka ʻai. Kahi ʻia ka noho ʻaiā ʻo Metglib, ʻoi aku ke ʻano o ka metabolism.

ʻO ka maʻamau, ʻo ka pākaukau mua o Metglib he 1 papa (2.5 mg glibenclamide a me 500 mg metformin), me kahi koho koho hōʻemi i nā he 1-2 wiki, e pili ana i ka glycemic index.

Ke hoʻopili nei i ka hoʻohuihui hui ʻana me ka metformin a me ka glibenclamide (e like me nā mea kaʻawale), ua kau ʻia nā papa 2 1-2 (2.5 mg glibenclamide a me 500 mg metformin), e pili ana i ka hala o mua o kēlā me kēia mea.

ʻO ka nui loa o ka lā i helu ʻia he 4 mau papa (2.5 a i ʻole 5 mg o ka glibenclamide a me 500 mg o ka metformin).

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa i ka ʻano o nā papa bīkopa lapuwale i hoʻopili ʻia me ka ʻula keʻokeʻo. Hoʻopili ʻia nā papa i nā palaka o 20 mau ʻāpana. Kuhi ʻia lākou i nā kāleka kāleka o 2, 3 a i ʻole 5.

Nā ʻōkuhi no ka hoʻohana ʻana iā Glibomet (ke ʻano a me ka helu ʻana)

Kau ke kauka i ka hoʻoponopono a me ka manawa o ka papa e mālama ai i kēlā me kēia kanaka, e pili ana i ka pae koko o ka mea maʻi a me ke ʻano o kāna metabolism.

Pono e kau ʻia nā maʻi pākahi i nā papa he 1-3 i kēlā me kēia lā, e ukali ʻia e kahi koho ʻana o ka ʻona loa maikaʻi loa.

Lawe i ʻelua lā i ka wā o ka ʻaina kakahiaka a me ka ʻaina ʻaina. ʻO ka dosis i kēlā me kēia lā e like me ke kauoha, ʻaʻole pono e hoʻonui i nā papa 6 papa.

Hoʻohui nūhou

• ʻO ka hopena hypoglycemic o ka lāʻau e hoʻonui nui ʻia i ka wā e lawe ana me ka dicumarol a me nā mea waiwai, beta-blockers, cimetidine, oxytetracycline, sulfanilamides, allopurinol, MAO inhibitors, phenylbutazone and its derivatives, probenecid, chloramphenicol, salicylinone anion ka nui nui.
• Hiki ke emi iho ka hopena o ka lāʻau me ka hoʻohana pū ʻana me ka epinephrine, nā hormone thyroid, glucocorticoids, barbiturates, thiazide diuretics a me nā kūmole waha.
• Me ka hoʻohana like ʻana o ka lāʻau lapaʻau me nā anticoagulants, hiki i ka hoʻonui ʻia o ka hopena o ka mea hope.
• Ke lawe ʻia me ka cimetidine, he piʻi nui ka hopena o ka hoʻomohala ʻana i ka waikena lactic acidosis.

He kumukūʻai ma nā lāʻau lapaʻau

Hoʻololi ʻia ke kumukūʻai Glibomet no 1 mau pahu mai 280 mau rubles.

ʻO ka ho'ākāka ʻana ma kēia ʻaoʻao he kope maʻalahi o ka mana o ka hanana o ka lāʻau lapaʻau. Hāʻawi ʻia ka ʻikepili no ka ʻike pili wale nō ʻaʻole ia he kumu no ka hōʻike pilikino.Ma mua o ka hoʻohana ʻana i ka lāʻau lapaʻau, pono ʻoe e kamaʻilio i kahi loea a hoʻomaʻamaʻa iā ʻoe iho me nā ʻōlelo i ʻae ʻia e ka mea hana.