Hoʻolālā a me ka Hoʻolauna ʻOle

Chlorpropamide (Chlorpropamidum)

N- (para-Chlorobenzenesulfonyl) -N - propylurea.
ʻO ka paukū keʻokeʻo keʻokeʻo; kīwili a ʻono ʻole. Hoʻōlō pono ia i ka inu wai, benzene, acetone.
He kokoke i ke kime me ka butamide, ʻokoʻa ma ka hope i loko o ka para para o ka kinima benzene nona ka Cl atom ma ka pūʻulu CH3 a mahele o ka pūʻulu butyl (C 4 H 9) ma N 'he kōmole propyl (C 3 H 7).

Nā hopena hopena

Allergic reaksi, leukopenia (kahi i emi mai ka pae o leukocytes i loko o ke koko), thrombocytopenia (ka hoʻēmi ʻana o ka nui o nā platelets i ke koko), agranulocytosis (kahi kao nui o ka helu o nā granulocytes i loko o ke koko), ke nānā aku (ʻeha), kūmole jaundice ka pehu. ka lana ʻana o ka hua bile ma ka pālākiō.

Nā Hoʻohui

ʻO ka precomatous (ka piha piha o ka ʻike - ka hoʻomaka mua ʻana o ke kūkulu coma, ke ʻano i ka mālama ʻia ʻana o ka eha a me ka hoʻoliʻi kūloko) a me ka coma (hōʻemi i ka ʻike mua, ʻike ʻia e ka waiho ʻana o ke ʻano o ka hopena o ke kino me ka hoʻoulu ʻana i waho) nā kūlana, ketoacidosis (acidification ma muli o ka loaʻa nui o nā kino ketone i loko o ke koko - waena. nā huahana metabolic), nā keiki a me nā ʻōpio, ke hāpai a me ka lactation, nā maʻi maʻi maʻi pāpaʻi, nā maʻi renal impaired, leukopenia, thrombocyte a me granulocytopenia (noʻonoʻo ʻO ka emi ʻana o ka helu o nā platelets a me nā granulocytes i loko o ke koko), nā mea hoʻolapalapa, nā hopena alū i nā sulfonamides.
ʻO nā contraindications kūpono loa he jaundice a me ka hana aho o ka ate.

Chlorpropamide - nā hiʻohiʻona a me nā hiʻohiʻona o ke noi

No ka mālamaʻana i nā hui pū, ua hoʻohana maikaʻi kā mākou mea heluhelu iā DiabeNot. Ke ʻike nei i ka kaulana o kēia huahana, ua hoʻoholo mākou e hāʻawi iā i kou makemake.

ʻO ka hopena no ka maʻi mellitus type 2 e pili ana i ka hana ʻana o nā lāʻau lapaʻau i ke kō ʻana o nā hui like ʻole.

ʻO ka pili kēia o nā derivatives sulfonylurea.

ʻO kekahi o nā ʻelele o kēia hui he chlorpopamide.

ʻO ka ʻike nui o ka lāʻau lapaʻau

ʻO Chlorpropamide kahi hana ikaika e pili ana i ka derivatives no ka hopena o ka makahiki. ʻO kāna hui pharmacological a me nā mīkini synthetic hypoglycemic synthetic. ʻAʻole hoʻoheheʻe ʻia ʻo Chlorpropamide i ka wai, akā, ma kahi ʻē aʻe, hoʻomāliʻi i ka inu ʻula.

ʻAʻole e like me nā hanauna ʻē aʻe o ka derivatives o ka sulfonylurea, e hana koke ana ka chlorpropamide. E hoʻokō i ka pae kiʻekiʻe o ka glycemia, hoʻohana ʻia ma nā ʻano nui.

Hoʻomaopopo loa nā hopena ʻaoʻao o ka lawe ʻana i ka lāʻau i hoʻohālikelike ʻia me Glibenclamide a me nā luna ʻē aʻe o ka hanauna 2. Maʻaola me ka lawa ʻole o ka hana ʻana o ka hormone (insulin) a me kahi laʻa o ka hoʻēmi i nā aihue. Loaʻa ka hopena me ka chlorpropamide i nā mea maʻi me ka partip diabetes diabetes partial a me / a me nā maʻi type 2.

ʻO Chlorpropamide ka inoa generic inoa no kahi lāʻau lapaʻau. ʻO ia ke kumu o ka lāʻau lapaʻau (he ʻano ikaika). Loaʻa i nā papa.

Ka hana lāʻau lapaʻau

Loaʻa ka lāʻau lapaʻau i ka hopena hypoglycemic. Hoʻopili ka mea i nā pāhare pālala, hoʻoulu i ka mea huna o ka insulin. I loko o nā kiko a me nā huelo e hoʻopili ʻia e ka insulin, hoʻonui ka nui o ka receptors hormone.

Ma ke alo o ka insulin endogenous, hoʻemi ka nui o ka glucose. He hana antidiuretic. Ma muli o ka hana huna ʻana i ka insulin, loaʻa ka loaʻa o ka paona.

ʻO ka hoʻomaha ʻana i ka glycemia he liʻiliʻi i ka honi koko. ʻO Chlorpropamide, e like me nā sulfonylureas ʻē aʻe, e lawe ana i nā pilikia o ka hypoglycemia, akā i ka liʻiliʻi.

Ke hui pū ʻia me nā ʻaina hypoglycemic ʻē aʻe (biguanides, thiazolidinediones, ʻike i ka launa pū me nā lāʻau lapaʻau ʻē aʻe), ua hoʻemi iki ʻia ka dosage o ka hopena.

Lapaʻau lāʻau

Ma hope o ke komo ʻana i ka hana kūwili, hoʻopili maikaʻi ʻia ka chlorpropamide. Ma hope o hoʻokahi hola, aia ka waiwai i loko o ke koko, ʻo kona mau kikoʻī loa - ma hope o nā hola 2-4. Hoʻomili ʻia ka waiwai i ka puʻuwai. Hoʻolaha ka protein protein> 90%.

Ke hana nei ka lāʻau lapaʻau i ke ao holoʻokoʻa i ka hihia. ʻO ka pauʻana o ka hapalua-ola he 36 mau hola. Hoʻokuʻu ʻia ia ma ka urine (a ʻo 90%).

Nā hōʻailona a me nā contraindications

ʻO nā ʻōmina no ka hoʻohana ʻana nā non-insulin-hilinaʻi, a me ka maʻi insipidus maʻi. Ua hoʻonohonoho ʻia ʻo Chlorpropamide i nā hihia kahi i mālama ʻia ai ka mālama ʻana i ka meaʻai, ʻaʻole lawe mai nā lāʻau lapaʻau i ka hopena kūpono i ke hoʻoponopono ʻana i nā hōʻailona.

I waena o nā contraindications i ka hoʻohana ʻana o ka lāʻau lapaʻau ka mea:

• hypersensitivity a chlorpropamide,
• ʻAno maʻi type 1
• epersensitivity i kekahi sulfonylureas,
• metabolism me kahi hopena e pili ana i ka acidosis,
• thyroid
• ketoacidosis
• akeo a me nā uhao o ka hana,
• maʻi maʻi pāpaʻi
• hapai / lactation,
• kupuna a iā wai lā
• nā makahiki o nā keiki
• ka hana mau hou ʻana o ka hana chlorpropamide,
• mau kūlana ma hope o ka haʻalele ʻana o ka pancreatic.

ʻ a me ke kākele

Hoʻonohonoho ʻia ka lāʻau lapaʻau e pili ana i ke papa o ka maʻi maʻi a me ka hoʻomaha ʻana o ka glycemia. I ka loaʻaʻana o kahi uku kūpono ma ka mea maʻi, hiki ke hoʻemi ʻia. Ma ke ʻano he kānāwai, me ka maʻi maʻamau o ka lā 2, ʻo ke ʻano o kēlā me kēia lā he 250-500 mg. Me ka maʻi indipidus maʻi - 125 mg i kēlā me kēia lā. Ke hoʻoili ʻia i nā lāʻau ʻē aʻe, e pono ai ke hoʻoponopono ʻia ʻana.

Hōʻike nā ʻōlelo no ka hoʻohana ʻana i ka chlorpropamide i ka hoʻohana ʻana i ka lāʻau i ka hapalua hola i mua o ka papaʻaina. Pono ia e hoʻopau iā ia i ka manawa hoʻokahi. Inā hāʻawi ʻia ka dosage i emi iho ma lalo o 2 mau papa, a laila e lawe ʻia ka hoʻokipa i kakahiaka.

ʻO nā wikiō mai kahi loea e pili ana i ka maʻi diabetes a pehea e mālama ai iā ia:

Nā hiʻohiʻona noi

Ma mua o ka hoʻolālā ʻana i ka wā hāpai, pono ʻoe e haʻalele i ka chlorpropamide. Manaʻo ʻia ka maʻi diabetes type 2 me ka insulin e manaʻo ʻia e ke ʻano maikaʻi loa. I ka wā lactation, pili lākou i nā loina like.

Hoʻololi ʻia i ka lāʻau lapaʻau mai ka hapalua i kahi papa i kēlā me kēia lā, a laila e kuhikuhi ʻia no ka papa mua. ʻO nā mea maʻi me ka hana renal maʻi hepatic e pono ai he hoʻoponopono hoʻoponopono ʻia. I ka helu ʻana i ka papa o ka lāʻau lapaʻau i nā poʻe kahiko, ua noʻonoʻo ʻia ko lākou makahiki.

Ke koi nei ʻo ia no ka maʻi, pono ke hoʻemi ʻia ʻana ma ke ʻano. Lawe ʻia ka hoʻoponopono ʻana me nā loli i ke kaumaha o ke kino, ke kaumaha, ka neʻe ʻana i kekahi pae manawa hou.

Ma muli o ka nele o nā ʻike e pili ana i ka palekana o ka hoʻohana, ʻaʻole i kuhikuhi ʻia ka lāʻau lapaʻau i nā keiki. I ka hihia o nā hōʻeha, ma mua / ma hope o ka hana, i ka manawa o nā maʻi maʻi hopohopo, e hoʻokaʻawale ʻia ka mea maʻi i ka insulin.

Mai hoʻohana me Bozetan. Aia ma laila he hōʻike no ka hopena maikaʻi loa i nā maʻi i loaʻa i ka chlorpropamide. Kuhi lākou i ka hoʻonui ʻana i nā ʻōkuhi hepatic (enzymes). E like me nā waiwai o nā lāʻau ʻelua, ua hōʻemi ʻia ka ʻano o ka hoʻōla ʻana o nā waikawa bile mai nā papa. Hoʻopili kēia i kā lākou hōʻiliʻili, nāna e hele i ka hopena o kahi meaʻala.

Hoʻopili me nā lāʻau lapaʻau ʻē aʻe

Me ka hoʻohana pū ʻana o ka chlorpropamide a me nā lāʻau lapaʻau ʻē aʻe, e hoʻēmi paha ka hopena a hoʻonui paha. Kūloko paʻa i mua o ka lawe ʻana i nā lāʻau lapaʻau ʻē aʻe.

Ulu lāʻau 'ana ia lŘlŘ ka wā coadministered me insulina, nā hypoglycemic ai', biguanides, coumarin nā mea loaʻa, phenylbutazone, ai 'tetracycline, Mao nā mea kūpale, fibrates, salicylates, miconazole, streroidami, kane hormones, cytostatics, sulfonamides, quinolone nā mea loaʻa, clofibrate, sulfinpyrazone.

ʻO kēia mau lāʻau lapaʻau e hoʻonāwaliwali i ka hopena o ka chlorpropamide: barbiturates, diuretics, adrenostimulants, estrogens, contraceptives tableted, nui i nā kūmole nui o ka acid nicotinic, diazoxide, hormon thyroid, phenytoin, glucocorticosteroids, sympathomimetics, deretazolamide.

ʻO Chlorpropamide kahi aikoi hypoglycemic e pili ana i ka 1st 1st sulfonylurea derivatives. Ke hoʻohālikelike ʻia me kāna poʻe hahai, he haʻahaʻa hoʻohaʻahaʻa ia o ka hilo ʻana a me nā hopena hou aʻe. I kēia manawa, ʻaʻole hana ka lāʻau lapaʻau.

ʻO nā maʻi hoʻomalu i ka hānau hānau no ka maʻi maʻi

Hiki i kekahi mau ala ke hopena i ke kōʻai koko. E aʻo e pili ana i nā koho koho hānau no nā wahine me ka maʻi maʻi.

Pono ka wahine me ka maʻi hānai no nā pilikia like ʻole o ka wahine e kū ai, e like me ke koho ʻana i ke ʻano o ka hānau hānau. Akā, ʻaʻole e like me nā wahine i loaʻa ʻole i ka maʻi diabetes, pono e noʻonoʻo i ke ʻano o ka contraception i koho ai e hoʻopilikia i kāna kō koko koko.

ʻO ka maʻi maʻi pākahi a me nā piliona hoʻomalu

I ka wā ma mua, ʻaʻole i kuhikuhi ʻia nā lāʻau hoʻomalu hānau no nā wahine me ka maʻi maʻi ma muli o nā loli hormonal e hiki ai i ka mālama maʻi ke kumu. Hiki i nā dosis nui o ke kō ka nui o ka hopena o ke kō koko koko, ʻoi aku ka paʻakikī o nā wahine e hoʻokele i kā lākou maʻi. Eia nō naʻe, ua alakaʻi ka noiʻi ʻana i nā hoʻopukapuka hou i nā māmā o ka hui ʻana o ka hormone. ʻO nā peni hou, e like me ka mākaukau waha ʻo Jess, ʻoi aku ka palekana no nā wahine he nui, ʻaʻole wale me ka maʻi maʻi. Inā ʻaʻoheʻike iā ʻoe e hoʻohana ana i kēia contraceptive, heluhelu i nā loiloi e pili ana i nā papa. ʻO nā wahine me ka maʻi maʻi e hoʻoholo ai e hoʻohana i nā lāʻau lapaʻau hānau pono e lawe i ka palena haʻahaʻa loa e kaupalena ʻia ai ka hopena o ka lāʻau lapaʻau ma ka maʻi diabetes.

Akā, pono e hoʻomanaʻo nā wahine e lawe pū ana i nā piliona hoʻomohala i ka nui o ka mahuahua o ka myocardial infarction a i ʻole hōʻeha ʻia i loko o nā wahine e hoʻohana nei i kēia ʻano o ka contraception. No ka mea ua loaʻa i ka nui o ka maʻi me ka maʻi maʻi o ka naʻau, pono e nīnau nā wahine i kauka.

ʻO ka maʻi maʻi a me nā contraceptives hormonal

ʻO nā kīpoki mana hānau ʻaʻole wale ke ala e hoʻohana ai i nā hormones e pale ai i ka hānau ʻana. Aia nō hoʻi nā injections, implants, nā pihi a me nā paikeke.

Ke lilo nei nā ʻōlelo huna i kahi koho kaulana no ka mea hoʻokahi i hoʻopaʻa ʻia no ka depot medroxyprogesterone acetate (Depo-Provera) ke pale aku i ka wahine hapai a hiki i ʻekolu mau mahina. Ke hoʻohana nei i kēia ʻano, pono e noʻonoʻo nā wahine e pili ana i ka mālama hānau ʻana i ʻehā mau makahiki i ka makahiki. Eia nō naʻe, ʻo ka hoʻohana ʻana i ka maʻi ʻaʻai no ka progestin hormone, hiki paha i nā hopena ʻaoʻao e like me ka loaʻa ʻana o ka momona, ka ulu ʻana o ka lauoho i makemake ʻole ʻia, nā ʻeha, ke kaumaha, a me ka hopohopo.

Inā ʻaʻole ʻoe makemake e kuhihewa i kēlā me kēia mahina ʻekolu, hiki iā ʻoe ke hoʻāʻo i kahi hānau hānau. ʻO kēia kahi lāʻau-kaila palaka liʻiliʻi liʻiliʻi e kūpono i lalo o ka ʻili o kou pale. Ke kau ka mea i kahi implant, hoʻokuʻu ia i ka progestin, ʻo ka hoʻokō like ʻo ia ka nui o ka injection.

ʻO kekahi ʻaoʻao hou i hoʻokomo ʻia i loko o ka hui contraceptive, ʻo ia ka pūpū o ka vaginal, i hoʻopaʻa ʻia no 21 mau lā. Ke kau nei kēia apo i ka ʻāina kiʻekiʻe o ka maʻa, aia i kahi e waiho ai, ʻaʻole ʻoe e manaʻo. Hāʻawi wale i ke kani i ka progestin wale nō, akā ʻo ka estrogen, ʻo ia hoʻi, ʻo nā wahine i hoʻohana i ia ke ʻike i nā hopena ʻaoʻao e like like me nā tablet contraceptives.

ʻO ka mea hope loa, aia kahi pā contraceptive. E like me nā lāʻau lapaʻau ʻē aʻe, no ka laʻana, ka mea e kōkua iā ʻoe e hōʻalo i ka ulaula, hana ka patch contraceptive i ka wā e pili ana i ka ʻili. Hoʻokuʻu ka pale i ka estrogen a me ka progestin i hoʻokahi pule, a laila hoʻololi ia me kahi mea hou, ua hana ʻia no kēia he ʻekolu mau pule ma ka lālani. ʻAʻole paʻa ka pāpana no ka ha heʻehā mau makahiki (i ka manawa menstrual) a laila hana hou ka pōkole. Eia hou, hiki i nā hopena like ke like me nā pale mana o ka hānau ʻana a i ʻole nā ​​apo paha, a laila paha kekahi mau huhū ma ka wahi o ka ʻili e hoʻohana ai ʻoe i ka patch.

E like me nā lāʻau hoʻomalu hānau, hiki i nā ʻano ʻē aʻe o ke ʻano ka hopena i mea e pili ai i ka puna koko. Inā hoʻoholo ʻoe e hoʻohana i kekahi o kēia mau ala, pono ʻoe e hoʻoponopono i ka ʻai ʻana o kāu lāʻau lapaʻau maʻi.

Nā maʻi Diabetes a me nā hāmeʻa intrauterine

ʻO nā hana Intrauterine (IUD) nā mea i hoʻopili ʻia i loko o ka ʻōpū. Noho ka IUD no kahi manawa no ka manawa ke kāpae nei ke kauka. Nā kumu i ʻike ʻole ʻole ai nā kauka, hoʻomalu ka IUD i ka hua paʻū mai ke komo ʻana i ka pā ʻōpū a pēlā e kōkua ai i ka pale ʻana i ka wā hapai. ʻOiai aia ka IUD kūpono maikaʻi loa o ka hānau hānau ʻana, ʻo kekahi o nā mea pōpilikia i ka hoʻohana ʻana i ka mea hana i ka maʻi i loko o ka ʻōpū.

Aia ke kiʻekiʻe o ka wahine me ka maʻi diabetes i ke kiʻekiʻe o ka ulu ʻana i nā maʻi ma muli o ko lākou maʻi, no laila, ʻaʻole paha kēia ʻano o ka hānau hānau ʻana ke koho maikaʻi loa inā he maʻi maʻi ʻoe.

ʻO ka maʻi diabetes a me nā ala lāʻau no ka hoʻokūkū

Me nā hopohopo e pili ana i nā maʻi i hoʻoili ʻia, ua hoʻomaka ʻia nā ala lāʻau i waena o nā wahine. I ka paleʻana i ka sperm hiki i ke komo ʻana i ka ʻōpū, ka hopena o ka hānau ʻana, a me ka hoʻoiho ʻana i ka maʻi.

No ka hapanui o nā wahine, ʻo nā ala lāʻau hiki ke lilo i ka hopena ulu contraceptive maikaʻi loa, a me nā condoms a me nā diaphragms vaginal ʻaʻole pili i ke kō koko. He mea koʻikoʻi naʻe naʻe, i ka hoʻomaopopo ʻana i ka paʻa o nā ala pale he ʻoi aku ka nui o ka hōʻino ma mua o nā papa a pono e hoʻohana pono ʻia, me kēlā me kēia moekolohe. Eia kekahi, ʻoi aku ka nui o ka wahine me ka maʻi maʻi e pili ana i ka loaʻa ʻana o nā huehue i ka wā e hoʻohana ai i ka diaphragm.

Ma ka maʻi maʻi maʻi a me ka maʻi maʻi

ʻO ka mea hope loa, ʻo ia paha ke ala palekana palekana o ka hānau ʻana i ka hānau, ʻo ka hoʻomakei ʻana me ka hoʻohana ʻana i kahi kaʻina hana i kapa ʻia ʻo tubal ligation. Akā, eia naʻe kahi hana mau o ka contraception inā he wahine ke hoʻomaʻamaʻa ʻana. ʻO ka hilinaʻi o kēia ʻano ʻoi loaʻo Pro, a ʻo ka ʻoiaʻiʻo e hoʻomau mau ʻia i ke "kūʻē" inā ʻaʻole ʻoe he 100 pakeneka ke makemake nei ʻoe ʻaʻole makemake nā keiki.

ʻO kahi kumu ʻē aʻe i ke aloha ʻia i kēia ala no nā wahine me ka maʻi diabetes, ʻaʻole ia e pili i ka sterilisation i ka pae koko koko o ka wahine. Akā naʻe, ʻaʻole ia he hana me ka pilikia, ke komo pū me nā maʻi a me nā hoʻopiʻi ʻē aʻe.

ʻO nā mea āu e koho ai, he kumu kūpono o ka hānau ʻana i ka hānau ʻana he mea nui no ka wahine me ka maʻi maʻi, no ka mea, ʻaʻole i hoʻolālā ʻia ka hopena me ke ʻano o ka pilikia o ke olakino a me ke keiki. Ke lawe nei i ke kuleana no kāu olakino reproduction e hoʻokau iā ʻoe i ka noho o ke kaʻa.

No ka mālamaʻana i nā hui pū, ua hoʻohana maikaʻi kā mākou mea heluhelu iā DiabeNot. Ke ʻike nei i ka kaulana o kēia huahana, ua hoʻoholo mākou e hāʻawi iā i kou makemake.

Ke noi

Hoʻonohonoho ʻia ka ʻākāka pū kekahi, e noʻonoʻo ana i nā kuhikuhi o ka glycemia a me glucosuria. ʻO ka laʻana mua loa he 250 mg / lā, no nā poʻe maʻi kahiko - 100-125 mg / lā, 3 mau lā ʻo ka hoʻohana ʻana. A laila, hilinaʻi i ka hopena, hoʻemi iki ʻia ka nui a hoʻonui ʻia paha e 50-125 mg me kahi manawa o 3-5 lā. ʻO ka palena kiʻekiʻe loa o kēlā me kēia lā he 500 mg.

ʻO ka awelika mālama mālama maʻamau he 100-500 mg / lā, ma muli o ke kūlana o ka mea maʻi, ʻo ka nui o ka hoʻokele ʻana i ka 1 r / lā i ka wā kakahiaka. Ke hoʻololi nei i nā kīlani hypoglycemic ʻē aʻe me ka chlorpropamide, pono e hoʻokaʻawale ʻia nā lāʻau lapaʻau mua a e kau ʻia i nā chlorpropamide ma loko o kahi momona o 250 mg / lā.

ʻO ka hoʻohana lōʻihi ʻana o ka lāʻau lapaʻau e alakaʻi i kahi hōʻemi i ka hoʻoweliweli ʻana i nā hana hypoglycemic waha.Inā hoʻohui ʻia ka chlorpropamide i kahi lāʻau lapaʻau i hala (ma nā hihia i piʻi ʻole ai ka nui o nā lā he nui o ka insulin i ka 40 mau pūʻulu), hoʻemi ʻia ka nui o ka insulin i ka 50%.

Loaʻa ka hopena

- hypoglycemia o kēlā me kēia ʻano paʻakikī, hiki i ka coma,
- nā maʻi dyspeptic (nausea, luaʻi, ka ʻike i ka piha o ka ʻōpū),
- ʻiliwi AR (ʻulaʻula, urticaria),
- i kekahi manawa - leukopenia, agranulocytosis,
- luhi loa-jaundice obstructive, thrombocytopenia, aplastic anemia.

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

I loko. I ka maʻi maʻamau o ka maʻi hyperglycemia a me glucosuria, e hoʻomaka me ka 0.5 g i hoʻokahi lā i ka lā, i ke kakahiaka, 30 mau minuke ma mua o ka ʻaina.

I nā hoʻohālikelike iki o ka maʻi diabetes - mai ke ʻano he 0.25 g, i ka make ʻole o ka hopena i loko o 1 mau pule, ua hoʻonui ʻia ka nui i ka 0,5 g, a ma kekahi mau ala i 0.75 g. Me ka hana maʻamau o ka glycemia a me ka wehe ʻana o ka glucosuria, e hoʻemi iki ʻia ka nui ma ka 0.125 g i kēlā me 2 mau pule. I ka haʻalele ʻana o ka hopena o kahi pānaʻi o 0.75 g, he kūpono ʻole ka hoʻokele hou.

Me ka maʻi maʻi maʻi insipidus - 0.1-0.15 g / lā.

Nā ʻōlelo kikoʻī

ʻO ka mālama pinepine ʻana i ka hoʻoliʻiliʻi koko a ma hope o ka ʻai ʻana i ka glycosylated Hb, pono ka lā glycemia a me ka glucosuria.

No nā mea ʻeha, hoʻoweliweli ʻia nā hōʻeha, nā maʻi maʻi maʻi, i ka wā hāpai ʻana, ua hōʻike ʻia kahi hoʻololi iki o ka mea maʻi i ka insulin.

Hoʻomaʻamaʻa ʻia nā mea maʻi e pili ana i ka hiki o ka hopena hypoglycemic, ʻoiai i ka wā o nā maʻi intercurrent a i ʻole nā ​​wā o ka pono ʻole.

Hoʻohālikelike ʻia nā hōʻailona o ka hypoglycemia i ʻole a i ʻole i loko o ka poʻe makua me ka neuropathy autonomic a i ka manawa like i loaʻa i nā beta-blockers, clonidine, reserpine, guanethidine a i ʻole nā ​​sympatholytics ʻē aʻe.

Inā pono e hoʻokaʻawale i ka mea maʻi mai ka inika insulin i ka hōʻino waha i ka chlorpropamide, hiki koke ke kāpae ʻia nā inikua insulin, a inā loaʻa aku ka mea maʻi ma mua o 40 PIECES / lā, a laila hiki ke mālama ʻia me ka chlorpropamide me ka hoʻohaʻahaʻa 50% i ka hōʻemi o ka insulin i nā lā mua.

Ke koi nei ʻo ia no ka mellitus maʻi diabetes, hoʻonui ʻia ka naʻau o ka insulin (e hōʻemi paha i ka pono o ka lāʻau).

Hoʻololi ʻia ka hoʻoponopono ʻana o ka dosis me kahi loli ma ke kaumaha o ke kino o ke kanaka, ke ola, no ka mea hoʻonui i ka ulu o ka hypoglycemia.

I ka wā o ka mālama ʻana, pono e mālama ʻia i ka wā e alakaʻi ana i nā kaʻa a hana i nā hana ʻē aʻe paha e koi ai i ka piʻi ʻana o ka nānā a me ka wikiwiki o ka hopena psychomotor.

Nā nīnau, nā pane, nā loiloi o ka lāʻau Chlorpropamide

ʻO ka ʻikepili i hāʻawi ʻia e hana no nā lāʻau lapaʻau a me nā lāʻau lapaʻau. Aia nā ʻike e pili ana i ka lāʻau lapaʻau e pili ana i nā ʻōlelo i hoʻopili ʻia e ka mea hoʻopiʻi e ka mea hana. ʻAʻohe ʻikepili i hoʻopili ʻia ma kēia a ʻole kekahi ʻaoʻao o ka pūnaewele a mākou e hiki ke lawelawe ma kahi kūʻokoʻa pilikino pili me ka loea.

Lapaʻau

Hoʻoweliweli i ka hoʻokuʻu ʻana o ka insulin mai nā cell beta pancreatic a hoʻonui i ka nui o nā mea i hāʻawi i ka insulin i nā ʻenehana kūpono. He hana antidiuretic.

Hoʻonono maikaʻi ʻia mai ka hana mai ka digestive, ʻike ʻia i loko o ke koko i loko o ka hola mua ma hope o ka hoʻokele ʻana. C_max Loaʻa ma 2-4 mau hola_1/2 - Nā hola 36. Hoʻopau ʻia e nā keiki (80-90% o nā pona) no nā hola 96, e komo 20-30% ʻaʻole i loli. ʻO ka hopena hypoglycemic ma hope o kahi pākahi hoʻokahi he 24 mau hola.

Ke keu

Lāʻau: me ka maʻi hypoglycemia maʻalahi - ingestion o glucose i loko, hoʻoponopono hoʻoponopono aʻai ʻole paha ka meaʻai. Ma ka ʻōpio koʻikoʻi (paʻakikī iki ʻole) me ka coma a me nā hōʻino - ke hoʻopuka ʻana i kahi hopena glucose i ka intravenous 50% a me ka hoʻopihapiha ʻana o kahi hopena glucose% 10 (e mālama i nā pae momona o ke koko ma luna o 100 mg / dl), mālama kiaʻi i nā pae glucose koko no 24- 48 h

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