ʻO ka lāʻau lapaʻau Glidiab MV: nā ʻōlelo i hoʻohana ʻia ai, loiloi

ʻO ka Gliclazide he lāʻau lapaʻau hypoglycemic waha e pili ana i nā derivatives huikaʻi ʻO ka hanauna 2. Hoʻokomo ʻia ka hana o ka lāʻau lapaʻau i ka hoʻōla ʻana o nā cells-cell i pancreashana ʻana insulin, hoʻonui i ka hoʻoluʻu o nā kiko peripheral i ia, i hoʻonui hopena huna huna glucose a me ka hoʻouluʻana i ka hana intracellular gilikai synthetase iloko o ka kikoo kino. Ke hōʻemi nei ka lāʻau lapaʻau i ka manawa manawa mai ka manawa o ka ʻai ʻana i ka meaʻai a hiki i ka hoʻomaka ʻana o ka hana insulinhōʻemi kaʻukū papaha postprandial, a hoʻihoʻi hou i ka poʻe mua (mua) pūkuniahi huna huna (like me nā lāʻau lapaʻau ʻē aʻe huikaʻika hana nui ʻana i ka lua lua).

Hoʻohui pono i ka hoʻoponopono ʻana i ka hana hoʻoneʻe kalama gliclazide hoʻomaikaʻi microcirculationma ka hoemi ana pāwili hui a ʻāpono, ka hoʻōla ʻana o ka hoʻonaninui vascular, ka hoʻihoʻi ʻana o ke kaʻina pili fethinolysis parietal.

Hoʻomaʻamaʻaʻia ka lāʻau glidiab i ka hoʻoweliweli vascular adrenalinepale i ka hoʻokumu ʻana atherosclerosis a microthrombosis. ^ E Ha yM. Hōʻike i ka holomua o ka non-proliferative (background) retinopathy maʻi maʻi. ^ E Ha yM. Me ka hoʻomau lōʻihi, ʻike ʻia kahi lohi nui proteinuriake kūkulu ʻana ma luna o ka hopemaʻi nephropathy maʻi.

ʻO ka lawe ʻana i ka lāʻau lapaʻau, ma muli o kona hopena i ke ʻano mua ʻiliʻu insulin, ʻaʻole i ukali ʻia e ka uku paona a makemake nui hoʻi i kona hōʻemi ʻana i nā maʻi hānai, inā kūpono lāʻauʻai meaʻai.

Hoʻolālā waha gliclazide alakaʻi i kona komo piha ʻana ma ka hoʻoneʻe ʻana. TCmax i ka serum koko 4 hola (no nā papa MV - 6-12 mau hola). ʻO ka nakinaki ʻana i nā protein plasma me ka pae o 90-95%. Hoʻololi ka loli Metabolic i loko o ke kao me ka hoʻokuʻu o nā huahana hana ʻole hoʻokūkū. ^ E Ha yM. T1 / 2 mau hola 8-11 (no nā papa MV - 16 mau hola). Hōʻailona ʻĀina nā metabolites lawe ʻia e ka maʻi nui (ma kahi o 70%), a me nā pahu (12%). Ma kahi o 1% gliclazide i hoʻokaʻawale ʻia i ka urine.

Nā hōʻailona no ka hoʻohana ʻana

Hoike ʻia ʻo Glidiab no diabetes type 2 (NIDDM, non-insulin-dependant diabetes) me ka manawa like lāʻauʻai meaʻai a me ka luku anaka hoʻoikaika kino pilikia paʻakikī ināʻaʻole lākou i kūpono i ka wā ma mua.

Ua hoʻohana nui ʻia ka hoʻohana ʻana o Glidiab i:

• maʻi ketoacidosis maʻi,
• hana waiū,
• maʻi diabetes type 1,
• kanesiakoma,
• nā maʻi ākea nui/ʻōpala,
• ʻO kā comosmolar coma,
• leukopenia,
• nā kūlana hōʻeha, me ka pono e hoʻohana insulinkomo me nā hōʻeha, hana hoʻokelenui loa kuniʻa,
• paresis o ka ʻōpū,
• o ka hāpai ʻana,
• ālai ʻia,
• nā ala i hui pū ʻia e mea palupalu mea ʻai a me ke ʻano hypoglycemia (komo pū me nā maʻi hopohopo)
• pilikino haaheo i gliclazide a i nā mea ola ʻē aʻe
• i kou wā kamaliʻi.

Nā hopena hopena

ʻO ka hopena maʻamau a koʻikoʻi ka hopena o Glidiab hypoglycemia, ka mea pinepine i hana ʻia mai ka mau hewa ʻana o ka regimen dosage a me ka nele ʻole lāʻauʻai meaʻai. ^ E Ha yM. ʻO ke ʻano o ka hoʻohālikelike ʻana o kēia hoʻopiʻi ua ʻokoʻa a hiki ke hōʻike iā ia iho: poʻomanaʻopololi māliekoke nāwaliwalika hemolele hopohopo, hoohioliihuhū wahiʻelemakulehele mai lohi, hiki ʻole i ka noʻonoʻo, ʻike makaleuluu aphasianā hopena naʻau hāpau, āhāhuʻe, deliriumlilo, huahuanalowale o ka ike ana hypersomniapuʻu papaʻu kaohuu, brieociaia.

ʻO ka hopena ʻelua corking koʻikoʻi o ke keʻena ʻo Glidiab i manaʻo ʻia i nā hopena maikaʻi loa e ʻike ʻia mai ka gastrointestinal tract, i hōʻike ʻia. ʻumiina (nininiepigastric Severity a nā ninia), hoʻopōʻino hana hepatic (hoʻonui i ka hanatransaminase ate, jaundice cholestatic), anorexia (i ka hihia o ke lawe ʻana i nā pōpoki me ka meaʻai, koʻikoʻi anorexia hoʻemi).

E ulu pū kekahi nā mea hoʻonāukiukikū nui nui i loko urticaria, rula makulopapular a kaʻiliʻili.

I kekahi manawa i nānā ʻia leukopenia, thrombocytopenia a anemia.

ʻO Glidiab, nā ʻōlelo aʻoaʻo no ka hoʻohana

ʻO ka koho o ka regimen dosage o ka lāʻau Glidiab e lawe pono ʻia e like me nā hōʻike kulana NIDDM a me ka pae glycemia, kahi e anaia ma ke aniani, a mahope o ka hora 2 o ka ai ana.

I ka hoʻomaka, ua hoʻolaha ʻia ke kōpono o kēlā me kēia lā o ka papa pā 1 Glidiab 80 mg a i ʻole ka papa ʻaina Glidiab MV 30 mg. ʻO ka awelika nui o kēlā me kēia lā he 160 mg a 60 mg, a ʻo ka nui he 320 mg a me 120 mg, kēlā, no nā papa a me nā pilahi MV. Lawe ʻia nā papa pākuʻi Glidiab 80 mg mau minima 30-60 mau minuke ma mua o ka papa ʻai ʻelua i 24 mau hola (kakahiaka a me ke ahiahi). Hōʻike ʻia nā papa inoa he 30 mau mg i lawe i kēlā me kēia kakahiaka i ka wā kakahiaka. Hiki ke mālama ʻia nā ʻōpiopio me kahi wā o 14 mau lā.

ʻO nā maʻi āpau a me nā maʻi me ʻōpala lolo (me CC 15-80 ml / min) ʻaʻohe pono o ka hoʻoponopono hoʻoponopono ʻia.

Ke keu

I kahi o ka overdose gliclazide atiina hana hoʻomohala hypoglycemiai kekahi manawapiko comoglycemic.

I ka hanana ʻana nā hōʻailona o kahi overdose e hoʻomaopopo ʻia ka mea maʻi, pono ia e inu koke haʻuki gula a i ʻole kekuhi (hoʻolaha) Ma kahi kūlana ʻole i ka hoʻomanawanui, hōʻike ʻia ka hopena intravenous Dextrose (40%) a i ʻole ke aloha IM Hoʻolau (1-2 mg). I ka wā e hiki mai ana, me kekahi o ka maʻamau o ke kūlana, pono ka mea maʻi e ʻai i nā meaʻai me kahi kīʻaha kiʻekiʻe kalapu, no ke kuana o ka hoike ka hoʻihoʻi ʻana o ka hypoglycemia.

Hoʻohui

ʻO ka emi ʻana o ka hana hypoglycemic Glameab e ʻike ʻia me ka hoʻohana pū ʻana me ia nā glucocorticoids, pani ʻiakaukaʻala (Terbutaline, Epinephrine, Ritodrin, Clonidine, Salbutamol), nā calcium antagonist, nā lithium salts, hoʻōla nicotinic, diuretics thiazidecarbonic anhydrase inhibitors (Diacarb), Chlortalidone, Na Triamteren, Chlorpromazine, Puʻu, Asparaginase, Danazol, Baclofen, Diazoxide, Rifampicin, Moramona, Isoniazid, Hoʻolau, Phenytoin, hona kelima puaa a estrogen (komo nā mea hoʻohālikelike waha).

Hoʻonui ʻia ka hana hypoglycemic o Glidiab me ka hoʻohana pū ʻana me ka lāʻau antifungal (Fluconazole, ʻO Miconazole), ʻAe aku ʻo ACE (Enalapril, Kanakaole), H2-blockers (ʻO Cimetidine) ana,Bezafibrat, Hoʻopili), Nā NSAID ((Nā Indomethacin, Phenylbutazone, Diclofenac), nā salicylates, nā lāʻau anti-TB (Ethionamide), nā mea kanu anticoagulants, β-blockerssteroids anabolic CyclophosphamideMAO ka mea paʻa Chloramphenicol, Theophylline, Allopurinolmolfonamides lohi, Fenfluramine, Pentoxifylline, Hoʻolālā, ʻO Guanethidine, Kahuliehu, mea ʻala pale poloka Disopyramide, Bromocriptine, ʻO Pyridoxine, ka ethanol, a me nā lāʻau lapaʻau hypoglycemic ʻē aʻe (insulin, nā biguanides, acarbose).

He lokomaikaʻi ʻo Glidiab a me cardiac glycosides hoʻonui i ka pilikia o ka hoʻokumu extrushstole ʻano.

Nā hopena o ka β-blockers, Kahuliehu, Clonidine, ʻO Guanethidine hiki ke nānā aku i nā maʻi lapaʻau hypoglycemia.

Nā ʻōlelo kikoʻī

ʻO ke kālai ʻia e kākoʻo ʻiahaʻahaʻa hoʻolaʻa haʻahaʻa haʻahaʻame ka hoʻopili liʻiliʻi ʻana kalapu.

ʻO nā huliʻana i ka meaʻai, a me ke olakino a me ke koʻikoʻi ʻana i ke kino e pono ai ka hoʻoponopono ʻana i ka dosage gliclazide.

Ma ke ʻano o ka papa hana, pono e nānā pae kiʻekiʻe glycemianānā iā ia ma kahi ʻōpū ʻole a ma hope o ka ʻai ʻana.

I decompensation huehueaoiaʻe wawao opala pono e noʻonoʻo ʻia ka hoʻohana ʻana ʻike i ka insulin hoʻomākaukau.

Pono e ʻike ʻia ka mea maʻi e pili ana i ka hiki ke hoʻokumu hypoglycemia i ka wā e ʻaina ai, e lawe ana Nā NSAID a ka hoʻomākaukau ʻana no ka ethanol.

Hoʻomaʻamaʻa nui ʻia i nā hopena o nā lāʻau hypoglycemic nā poʻe maʻi maʻi, nā mea nāwaliwali nāwaliwali, a i ʻole nā ​​mea i loaʻa ʻole ka meaʻai kaulike, me ka poʻe e hōʻeha nei hypocorticism.

Pono e mālama ʻia i ka mālama ʻana i ka wā e hana ai i ka hana ʻeha a pololei hoʻi, me ka mālama ʻana i kekahi kaʻa, ʻoiai i ka wā o ke koho ʻana o ka hoʻoponopono dosage, ma muli o ka hoʻonui nui o ka hoʻokumu. hypoglycemia.

• Glemaz,
• Amaril,
• Glairy,
• Amix,
• Hoʻolālā,
• Diabrex,
• ʻO Glianov,
• Maninil,
• ʻO Glibenclamide,
• Diameprid,
• Glimepiride,
• Diapiride,
• ʻO Glinova,
• Meglimide,
• Kuiluna,
• Alarahi,
• Hoʻopau etc.

• ʻO Glidia MV,
• Diabeton MR,
• Gliklada,
• Hoʻololi,
• ʻO Gliclazide MR,
• Diagnizide MR,
• Gluktam,
• Diabinax,
• Hula,
• Nā Diula,
• Glioral,
• Diabresid,
• Osiklid.

ʻAʻole lawa ke ʻike no ka hoʻomaʻamaʻa ʻana o Glidiab i nā maʻi i nā makahiki ʻōpio o nā keiki.

Me ka waiʻona

Inā inu ʻoe i ka wai inu ke lawe nei i ka lapaʻau ʻo Glidiab, ʻike paha ʻoee like me ka disulfiram-like manaʻo (ʻĀpana) hōʻike i ka ʻeha ka ʻōpū, ninini/utuka, poʻomanaʻo.

I ka wā hāpai a me ka lactation

Hoʻohana i ka mālamaʻana iā Glidiab me hana waiū a o ka hāpai ʻana papaia.

Loaʻa nā loiloi Glidiab ma ka upena he liʻiliʻi, akā ʻano maikaʻi. Wahi a nā mea maʻi e loaʻa ana, paʻi ke lāʻau lapaʻau me nā hōʻike maikaʻi ʻole. non-insulin dependant diabetes a he liʻuliʻu liʻiliʻi o nā hopena ʻaoʻao. ʻOiaʻiʻo, i ka wā e lawe ai iā Glidiab, pono e mālama i ka kūpono mea ʻai a hahai i nā ʻōlelo kuhikuhi no ka hoʻoikaika kino.

E hoʻokuʻu i ke ʻano a me ka ʻano

ʻO ka papa ʻaina no ka hoʻokuʻu ʻana o Glidiab MV he papa papa me kahi hoʻoneʻe i hoʻololi ʻia: flat-cylindrical, keʻokeʻo me kahi ʻono ʻono a i ke keʻokeʻo paha, beveled, ʻae ʻia nā marbling (ʻāpana he 10 i nā blisters, i loko o kahi pūlani pepa o nā 3 a 6 paha mau pā).

Helu 1 papa:

• mea waiwai: gliclazide - 30 mg,
• ʻO nā mea kōkua: microcrystalline cellulose - 123 mg, hypromellose - 44 mg, magnesium stearate - 2 mg, silikone colloidal dioxide - 1 mg.

Lapaʻau lāʻau

ʻO Gliclazide ma hope o ke kaʻina waha he mea piha loa ia mai ka gastrointestinal tract. Hoʻonui pinepine ʻia kona kaila kiʻekiʻe a hiki i kahi lōʻihi i loko o nā hola 6-12. ʻO ka ʻai ʻaʻole e hoʻopilikia i ka hoʻopili ʻana o ka waiwai.

Me kahi pākahi hoʻokahi o ka Glidiab MV i kēlā me kēia lā, hāʻawi ʻia ke kinikini plasma pae kūpono e hoʻolako ʻia ai nā gliclazide no 24 mau hola.

ʻO ka pilina o ka protein plasma e pili ana i ka 95%.

Hoʻopilikia wale ka mea hoʻokūkū i ka ate me ka hoʻolālā o nā metabolites i ʻole.

T_1/2 (hapalua-ola) aneane 16 mau hola. Hoʻokuʻu ʻia ia ma nā kumuʻai a i ke ʻano o ka metabolites, ma kahi o 1% o ka waiwai i hoʻololi ʻia i ka urine.

Nā Hoʻohui

• maʻi diabetes type 1
• maʻi maʻamau ketoacidosis,
• maʻiʻeleʻele coma / precoma,
• nā kūlana i hui pū ʻia me ka malabsorption o ka meaʻai, ka loaʻa ʻana o ka hypoglycemia (nā maʻi ʻeha),
• pāpale pākole,
• paresis o ka ʻōpū
• leukopenia
• loaʻa ʻole hepatic / renal failed,
• ālai ʻole,
• interventiveh operation 'ole, hanana hoeha nui, Burns, a me na mea e ae e pono ai ka therapy insulin,
• hui pū me nā miconazole, danazole a phenylbutazone,
• makahiki i 18 makahiki
• hapai a me lactation,
• ka molaki ʻana o kēlā me kēia o nā mea pono o ka lāʻau lapaʻau, a me nā sulfonamides a me nā mea hoʻopuka sulfonylurea ʻē aʻe.

Relative (Glidiab MV i kuhikuhi ʻia ma lalo o ka mākaʻi loea)

• ʻiliʻala maʻi
• waiʻona
• ke kaupaona ʻole / kaʻai ʻai,
• lawa lawa / lawena
• nā maʻi koʻikoʻi o ka ʻōnaehana cardiovascular (me ka atherosclerosis, ka maʻi naʻau coronary).
• kōleʻa / lawelawe kōleʻa
• hipapoliona,
• Iʻa nele o ka glucose-6-phosphate dehydrogenase,
• hoonui pinepine ana o ka glucocorticosteroids,
• ka maʻi thyroid, ka hoʻomau ʻana me kāna hana hewa,
• hiʻona kiʻekiʻe.

Nā ʻōkuhi no ka hoʻohana ʻana i ka Glidiab MV: kaʻina a me ka helu ʻana

Lawe ʻia ka Glidiab MV i ka ʻōlelo maʻamau, 1 manawa i kēlā me kēia lā i ka ʻaina kakahiaka.

ʻO ke ʻano o ka lāʻau lapaʻau ke koho ʻia e ke kauka ponoʻī e pili ana i nā hōʻike ʻana o ke ʻano o ka maʻi, ka wikiwiki o ka glucose a me 2 mau hola ma hope o kahi pāʻina.

ʻO ka papa ʻōlelo pākahi mua i kēlā me kēia papa 1 papa. I ka wā e hiki mai ana, inā pono, e hoʻonui i ka nui me ka papa manawa ma ka liʻiliʻi 2 mau pule. ʻO ka nui maʻa loa he 4 papa no ka lā.

Hiki iā ia ke hoʻololi mai Glidiab i Glidiab MV i loko o kahi lā i kēlā me kēia papa nui o ka papa ʻaina i ka papa ʻaina.

Hiki ke hoʻohui ʻia ka Therapy me nā mea hana hypoglycemic ʻē aʻe: biguanides, insulin a iʻole alpha-glucosidase inhibitors.

Hoʻohui nūhou

Hoʻopili i nā mea e piʻi ai ka nui o ke koko (nāwaliwali i ka hopena o ka gliclazide):

• ʻO ka danazol: ʻaʻole i koi ʻia ka hui ʻana, he hopena maʻi ka maʻi lapaʻau, inā hiki ʻole ke hoʻololi iā ia me kekahi lāʻau lapaʻau ʻē aʻe, ke nānā ʻia ka ʻike o ka glucose i ke koko, e hiki ke hoʻoponopono ʻia ke ʻano o ka Glidiab MV e ka kauka i ka wā o ka hui pū ʻana a ma hope o ka pau ʻana.
• chlorpromazine (ma kahi o kēlā me kēia lā he 100 mg): pono ka hui ʻana e mālama, no ka mea, ua nui ka hoʻonui ʻana o ka puhī i loko o ke koko a me ka hoʻēmi ʻana i ka mea huna o ka insulin, inā ʻaʻole hiki ke hoʻololi hou ʻia me kahi lāʻau ʻai hou, ʻo ka hoʻomohala o ka glucose i ke koko e nānā ʻia, i ka wā o ka hui pū ʻana a ma hope o kona kū ʻana, hiki paha i ke kauka ke mālama. Hoʻoponopono ʻia ka nui o Glidiab MV,
• tetracosactide a me glucocorticosteroids (ka waena / hoʻohana ʻana i ka ʻōnaehana: intraarticular, rectal a me ka hoʻoponopono o waho): pono ka hui ʻana me ka makaʻala, no ka mea, he nui ka piʻi ʻana o ka glucose o ka toto me ke kūkulu ʻana i ka ketoacidosis, ua manaʻo ʻia e mālama pono i ka hoʻoliʻi ʻana o ka hoʻokaʻina o ke koko, ai ka hoʻomaka ʻana o ka maʻi, i ka wā o ka hui pū ʻana. ʻoi aku ka hopena a ma hope o ka hoʻopau ʻana i ke kauka, hiki ke hoʻoponopono ʻia i ka lāʻau o Glidiab MV,
• salbutamol, ritodrin, terbutaline (hoʻokō intravenous): pono ka hui ʻana me ka mālama,
• anticoagulants (ma ke ʻano he warfarin): hoʻonui i ka hana o nā anticoagulants (pono e koi ʻia ka hoʻoponopono ʻana).

ʻO nā hui i loko o ka hopena o ka uluʻana o ka hypoglycemia e hoʻonui (hoʻonui i ka hana o gliclazide):

• ʻO ka miconazole (ʻōnaehana a i ʻole ke kūloko i ke aniani i ke ʻano o ka gel ma nā membouss mucous o ka waha waha): ua hui ʻia ke hui ʻana, no ka mea hiki i ka hypoglycemia ke ulu a hiki i kahi coma.
• ʻO ka phenylbutazone (hoʻokōnaehana hoʻonohonoho): ʻaʻole i ʻāpono ʻia ka hui, inā ʻaʻole hiki ke hoʻololi hou iā ia me kekahi lāʻau lapaʻau ʻē aʻe, ke nānā ʻia ka ʻike o ka glucose i ke koko, e hiki ke hoʻoponopono ʻia ke ʻano o ka Glidiab MV e ka kauka i ka wā o ka hui pū ʻana a ma hope o ka pau ʻana.
• ethanol: ʻaʻole i aʻo ʻia ka hui ʻana, ka mea i hoʻopili ʻia me ka hypoglycemia i hoʻonui ʻia a me ka hopena o ka hoʻomohala ʻana i ka comog hypoglycemic,
• nā hana āpau hypoglycemic ʻē aʻe (insulin, alpha-glucosidase inhibitors, metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 agonists), nā mea hoʻohana anti-inflammatory anti-inflammatory, fluconazole, beta-adrenergic blocking agents, neurotransmitter antagonists, inhibitors.₂- nā mea i hoʻopaʻa, histamine, monoamine oxidase inhibitors, clarithromycin, sulfonamides: pono ka hui ʻana e mālama.

ʻO nā analogues o Glidiab MV nā: Diabeton MB, Diabefarm MV, Gliclazide Canon, Glidiab, Gliclada, Diabetalong, Diabinax, Diabefarm.

ʻO keʻano maʻamau

ʻO ka lāʻau lapaʻau "Glidiab MV 30" ke manaʻo ʻia ka analogue Lūkini o ka loea Farani "Diabeton MV". Kuhi ʻia ia e Akrikhin Chemical and Pharmaceutical Plant ma ka Moku o Moscow.

ʻO ka lāʻau lapaʻau e pili ana i nā ʻaihue hypoglycemic waha i ka puka papa me ka hoʻoiho ʻia. Ke keʻokeʻo a ʻona paha ke kala o ko lākou ʻano, he mau kinipōpō marmele. Ua like nā papa ma nā pani chamfers.

Mea hoʻohana ʻeke pepa kūʻai aku. Loaʻa he 30 a 60 paha mau papa, i waiho ʻia i nā papa blister.

ʻAʻole i like me ka lāʻau lapaʻau "Diabeton MV" me kahi pona o 0,060 g o gliclazide, ke lāʻau lapaʻau "Glidiab MV" he nui o nā mea hoʻomohala kaha i ʻelua mau manawa i lalo, ʻo ia ka 0,030 g.

I nā papa papa hana ikaika me ka cellulose hydroxypropylmethyl, nā moleki aerosilic, magnesium stearate, cellulose microcrystalline.

Aia pū kekahi lāʻau "Glidiab" me ka hoʻokuʻu maʻamau o ka mea ikaika. ʻO ka hewa ma ka papa hoʻokahi he 0.08 g o gliclazide.

Pehea e hana ai

ʻO nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana i pili i ka lāʻau hoʻolaʻa Glidiab MV e wehewehe i ka hopena o ka glyclazide, ka mea e hoʻoulu ai i ka mea huna o ka insulin i loko o nā β-cell i loaʻa i ka pancreas.

Ma lalo o ke aʻo ʻana o nā papa, ka piʻi ʻana o ka hana huna o ka insulin i nā moleki glucose, a nui ka naʻau o peripheral i makaʻala i ka hormone insulin.

ʻOi aku ka nui o ka naʻau glycogen synthetase, he enzyme intracellular i ʻoi aku ka maikaʻi. Hoʻomaopopo ka hapa o ka manawa mai ka hoʻomaka ʻana o ka ʻai a hiki i ka hoʻokuʻu i kahi o ka hormone. Hoʻihoʻi ʻia ka hoʻonaʻauao Insulin ma ke aniani kiʻekiʻe, ka mea e wehe ai i ka gliclazide mai nā mea hele mua o ka ʻalālani. Ua emi ka pae o ka glucose postprandial.

Loaʻa kahi hoʻomaikaʻi ʻana i ka microcirculation ma muli o ka hoʻohui ʻana a me ka hoʻopili ʻana o nā ʻāpana platelet, ka hoʻōla maʻamau o ka pono o ka pā vascular, kahi hoʻohaʻahaʻa i ka hoʻomohala ʻana i nā ʻōnaehana microthrombotic a me ka atherosclerosis, a me ka hoʻihoʻi hou aku i nā hopena o ka luku kūlohelohe o nā kīwaha koko. ʻO ka hopena o ka hopena o ka hoʻopiʻi ʻana i nā mea hoʻoponopono i loko o nā moku koko i nā molekui adrenaline e emi.

Hiki i ka lāʻau lapaʻau ke hoʻolōʻihi i ke ʻano maʻi diabetes o ka retinopathy ma ke kahua mua-proliferative. ʻO ka mālama lōʻihi ʻana i kēia lāʻau lapaʻau i nā kūlana o ka hōʻemi kino o nā maʻi i nā mea o nā ʻāpana o ke koena i kuleana no ka filtration e hiki ke hoʻemi i ka hōʻoki ʻana i nā protein i loko o ka urine.

ʻAʻole hoʻonui ka lāʻau lapaʻau i ka nui o ke kino, akā hoʻohaʻahaʻa iā ia ma muli o ka hopena i ka wīwī o ka hana huna ʻana i ka insulin. ʻAʻole ia e hoʻonāukiuki i ka insulinemia.

He aha ia e hoʻohana ai i ka?

Hoʻomaopopo nā kauka i ka hoʻohana ʻana i ka lāʻau lapaʻau me ke kō koko kiʻekiʻe o ke kekona. Hoʻopili ʻia ka mālama ʻana me ka hopena ʻole o ka meaʻai a me ka hoʻomaʻamaʻa ʻana i ke kino.

No ka lāʻau lapaʻau Glidiab MV, pili nā hōʻailona i ka pale ʻana i ka hoʻēmi ʻana i nā maʻi ma ka maʻi maʻi, hōʻailona ʻia e nephropathy, retinopathy, myocardial infarction a me ka hahau.

Pehea e hoʻohana ai

Koho ʻia ka nui o ka lāʻau no kēlā me kēia mea maʻi e hoʻokaʻawale, me ka noʻonoʻo ʻana i nā hōʻike o ka maʻi, ke kūpaʻa ʻana o ka glucose me kahi ʻōpū ʻole a me nā minuke 120 ma hope o ka ʻai.

No ka lāʻau lapaʻau "Glidiab MV", nā ʻōlelo no ka hoʻohana ʻana i kuhikuhi i kahi lā mua ma mua o ka 0,03 g, kahi mea like me hoʻokahi papa. Hōʻike ʻia kēia kaila no nā poʻe maʻi ma hope o 65 mau makahiki o kona mau makahiki. Hoʻohana ʻia ka lāʻau lapaʻau i kahi papa hoʻokahi i ke kakahiaka i ka ʻaina kakahiaka.

Inā kūpono, hoʻonui ʻia ka dosage i kēlā me kēia pule ʻelua. Loaʻa ka lōʻihi o hoʻokahi lā e lawe ma kahi o 0.120 g, kahi kūpono e like me 4 papa.

Hoʻohana ʻia ka lāʻau lapaʻau "Glidiab MV" ma kahi o ka lāʻau lapaʻau o ka inoa like me ka mea maʻamau, e hoʻopau ana i nā papa papa 1-4 i kēlā me kēia lā.

Hoʻohui pū ʻia me ka ʻaihue hypoglycemic pili i ka biguanide, kahi hoʻomehana alpha-glucosidase o nā molekina insulin.

Ma ka hihia o ka hana kumu kīpē o kahi ʻano nāwaliwali a hōʻino paha, ke kū ʻole o ka nui o ka excretion o ka creatinine ma mua o 0,080 lita mau minuke, ʻaʻole i hōʻemi ʻia ka dosage.

Ke lawe ʻole ia

ʻAʻole ʻōlelo ʻia nā papa o Glidiab MV i ka hoʻohana ʻana i ka puka mua o ka maʻi mellitus, me ka piʻi ʻana o ka ketones i loko o ka pā, a me ka paresis gastric, me ka hyperosmolar, ka maʻi diabetes a me ka precoma, me nā hōʻeha nui a hoʻomake i nā hōʻeha, nā hana traumatic i ka wā e pono ai ka insulin hana

ʻO nā Contraindications ka nui o ka hōʻino ʻana i ka hana hepatic a i ʻole ka hana ʻana, ka pākīpū i loko o nā wahi, nā hoʻololi i ke kū ʻana o ka meaʻai, ka hoʻomohala ʻana i kahi kūlana hypoglycemic.

ʻAʻole hiki iā ʻoe ke hoʻohana i ka lāʻau lapaʻau no ka maʻi, leukopenia, ka hāpai ʻana, ka umauma a me ka luhi nui ʻana i nā mea lapaʻau.

Pono ʻia ka mālama ʻana i ka wā e lawelawe ai i ka lāʻau lapaʻau, mālama kūikawā a me ke koho ʻana i ka dosage no nā mea maʻi me ka hilinaʻi i ka waiʻona a me nā pilikia o ke kelepaʻo thyroid.

Nā hiʻohiʻona hana

No ka lāʻau lapaʻau "Glidiab MV", i nā kuhikuhi no ke hoʻohana e hōʻike i ka pono e hoʻohui pū me ia me ka meaʻai haʻahaʻa-haʻahaʻa, me ka haʻahaʻa haʻahaʻa haʻahaʻa. ʻO ka mālama pinepine ʻana i ka neʻe o ka glucose i ke kahe wai mai ke kakahiaka ma mua a ma hope o ka ʻai ʻia ke koi ʻia.

Inā he kaʻa hāpili a i ʻole hoʻokaʻawale i ke ʻano maʻi maʻi, hiki i ka hoʻokomo ʻana i nā mea hana i insulin.

Aia kahi luhi e pili ana i ka hiki ʻana o kahi kaʻao hypoglycemic me ka hoʻohana ʻana i ka etyl alkohol, he mea e non-steroidal anti-inflammatory a me ka nele o ka pono. Hiki i ka inu ʻona ke hōʻeha i kahi maʻi like o ka disulfiram, aʻo ka poʻo a me ka ʻōpū, hōʻeha ʻia, kaʻaʻi a me ka luaʻi.

Pono ke hoʻoponopono ʻia ka nui o ka lāʻau lapaʻau i ka wā o ke koʻikoʻi a i ke ʻano a me ka manaʻo ʻana me ka meaʻai ʻole o kaʻai.
Hoʻomaʻamaʻa koʻikoʻi loa i ka hopena o ka lāʻau lapaʻau ka poʻe ʻelemakule, nā mea maʻi me ka palaka ʻole a maikaʻi ʻole paha, nā nāwaliwali nāwaliwali e hoʻopilikia ai i ka nele o ka ʻoihana adrenal-pituitary

I ka wā mua o ka hoʻohana ʻana i ka lāʻau lapaʻau ke koho ʻana i kahi maʻa, inā aia kahi predisposition i kahi pilikia hypoglycemic, ʻaʻole pono ʻoe e hana i nā hana e koi ai i ka nui o ka nānā ʻana a me ke ʻano wikiwiki.

Nā hopena maikaʻiʻole

No Glidiab MV, aia ke aʻo e pili ana i ka ʻike e pili ana i nā abnormalities ma nā huaka endocrine i ka wā i hana hewa ʻia i ka hoʻoponopono regimen o ka hoʻohana ʻana i ka papa a i ka wā kūpono o nā meaʻai kūpono. ʻO ka maʻamau, ʻo ka hoʻohaʻahaʻa i ka glucose i loko o ke kahe wai e hōʻeha ai i ka hōʻeha, ka luhi, ka pōloli, ke kōkua ʻole, ka hopohopo, nāwaliwali koke, ka huhū, ka ʻōpū haʻahaʻa, a me ke kūlana kaumaha. Eia kekahi, loaʻa nā loli i ka ʻike maka ʻana, nā hana ʻana, ka naʻau a me ka hoʻomanawanui, nā dizziness, hypersomnia, ka papa ʻaina, a me ka hoʻemi ʻana o ka puʻuwai puʻuwai.

Ka hana ʻana o nā wahī i ka hana ʻana i ke ʻano o ka malabsorption, nausea, ke nānā ʻana i ka maʻi, anorexia, nele ʻole o ka makemake, ka hana ʻana o nā huina aina, jaundice cholestatic, a me ka hoʻonui aʻe i ka hana pono o nā enina transaminase.

ʻO nā hana e hikiʻole i ke keʻena hematopoietic e pili me ka hoʻohaʻahaʻa ʻana i ka hemoglobin, platelet a me nā leukocyte helu.

Hiki i ka lāʻau lapaʻau ke hōʻeha i nā hōʻike maʻi kūlohelohe i ke ʻano o ka heching, urticaria, maculopapular rash.

Hōʻikeʻike lōʻihi

Ke kuhikuhi aku nei nā ʻōkuhi no ka hoʻohana i pili i ka hoʻolaʻa Glidiab MV i kahi overdose, ka mea i hōʻike ʻia e ka hoʻohaʻahaʻa o ka glucose o ka glucose i loko o ke koko koko. Me ka nui o ka lāʻau, hiki i ka hiki ke hoʻomohala ʻia kahi comog hypoglycemic coma.

E kāpae, e ʻae ʻia kekahi kanaka e ʻai i kahi hydrocarbons maikaʻi loa, no ka laʻana, kahi ʻāpana kōpī. Ke ʻike ʻole ʻole kekahi kanaka, ua paʻi ʻia kahi hopena o 40% dextrose a i ʻole he glucose i loko o ka vein, a e pāloi ʻia ka glucagon i loko o ke ʻiʻo i ka nui o 1 mg. Inā e ala i ka mea hoʻomanawanui, a laila ua koi ʻia ʻo ia e ʻai maikaʻi i nā hydrocarbons e hoʻopale iki i ka pale ʻana i ka hoʻoulu ʻana o ka hypoglycemic attack.

E hui pū me nā lāʻau lapaʻau

Ke hypoglycemic ha awina o ka medicament "Glidiab CF 30 mg" hiki ke hoʻokāʻoi 'ia e laua angiotensin hoʻololi''ūhū inhibitor a me Monoamine oxidase type mea loaʻa blocker me ka ho okumu Hoʻokolohua adrenozavisimyh a me h2 gistaminozavisimyh ma muli cimetidine, a me flukonazolovyh mikonazolovyh antifungal ai ', ole-steroidal Anati-hoʻoʻino Luna phenylbutazone, indomethacin, diclofenac i hoʻolaunaʻia ma.

Hoʻonui ʻia ka hopena o nā papa me nā clofibrates a me bezafibrates, nā lāʻau anti-TB mai ka pūʻulu o ka ethionamide, salicylates, kūlohelohe anticoagulant pūhui o ka hanganga Coumarin, anabolic steroid, cyclophosphamides, chloramphenicol, sulfonamides me ka hopena lōʻihi.

ʻOi aku ka maikaʻi o ka lāʻau lapaʻau i ke kōpaʻa koko inā ke hoʻohana ʻana i nā tubular blockers, ethyl alkohol, acarbose, biguanide, insulin.

ʻO ka hōʻemi ʻana i ka hopena hypoglycemic tablet ma muli o ka barbiturates, nā lāʻau lapaʻau e pili ana i ka epinephrine, clonidine, terbutaline, rhytodrin, salbutamol, phenytoin, inhibitor o ka lālani anhydrase o ka lālama e like me ka acetazolamide, thiazide diuretics, hormones of the thyroid gland, heʻonama, a me ka lula o nā molika.

Hiki i nā molekule o ka ethyl alkohol ke hana i ka gliclazide me ka loaʻa o kahi hana disulfiram-like.

ʻO ka hana koʻikoʻi o nā papa e hoʻomau i ka depolarization untimely a me ka hoʻopiʻi ʻana i nā ventricles o ka uaua myocardial i hui pū ʻia me glycosides cardiac.

Nā beta-blockers, clonidine, reserpine, guanethidine drug mask mask hypoglycemia clinical.

ʻO nā manaʻo hoʻomanawanui

ʻAʻole ia he mea nui wale nō nā kuhikuhi no ka hoʻohana pili ʻia i ka lāʻau lapaʻau Glidiab MV. Hōʻike nā loiloi e pili ana i nā mea maʻi e pili ana i ka hopena o ka lāʻau lapaʻau. Ke kōkua nei kēia hāmeʻa i nā mea maʻi e hoʻemi i ka hoʻokaʻina glucose i nā kumu maʻamau, a i hui pū me ka meaʻai e hoʻololi i ke ʻano o ke ola o ka mea maʻi.

Hōʻike ka poʻe i ka maikaʻi o nā papa i ko lākou hoʻohana kūpono i ke kakahiaka. I ke ao, ʻaʻole hiki iā ʻoe ke hoʻomanaʻo i ka pono o ka mālama ʻana.

Ma ka lāʻau lapaʻau "ʻO Glidiab MV" loea hiki ke lohe a maikaʻi ʻole i loko o ke ʻano, pili pū me ka hikiʻole o kēia pono hana. Loaʻa kēia hana i ka hewa o ka dosage, ke ʻano o ka liʻiliʻi o ka lāʻau.

Nā hoʻonohonoho hoʻonohonoho a hoʻokuʻu i nā palapala

• Kōkua: 0,03 g o gliclazide
• Kōkua: hypromellose, MCC, aerosil, E572.

ʻO nā paila i ke ʻano o kahi cylinder papa me nā kihi beveled, keʻokeʻo a ʻemala paha. ʻO ka hōʻeha ʻana o ka hoʻonohonoho, ʻaʻole ia he kīnā. Hoʻopili ʻia ma nā ʻāpana he 10 i nā palaka. I ka pahu pepa - 3 a 6 mau papa ʻaina, hoʻohana manual.

Hoʻomaopopo i nā waiwai

ʻO ka lāʻau lapaʻau me ka hopena hypoglycemic pili i ka glycazide, kahi derivative o ka lua o ka hanauna sulfonylurea. Hoʻopuka i ka hana ʻana o ka insulin i ke kino, hoʻonui i ka ʻike o ka ʻiole i ka insulin a me ka hopena o ka insulin-secretory o ka glucose. Hoʻihoʻi i ka maʻamau o ka mea huna o ka inikini o ka insulin, hoʻomaikaʻi i ka microcirculation, hōʻemi i ka hoʻohui platelet, e hoʻihoʻi i ka pono vascular pono.

ʻO ka lawe ʻana i ka lāʻau lapaʻau ʻaʻole ia he kōkua i ka hōʻiliʻili o nā paona hou, no ka mea e pili nui i ka hoʻokumu ʻana o kahi ulu pōkole i ka mea huna o ka insulin.

Ke ʻano o ka noi

Hoʻolālā wale ʻia ka lāʻau lapaʻau no ka lapaʻau ʻo nā pākeke. ʻO nā papa kālele Glidiab, e like me nā ʻōlelo i hoʻohana ʻia, i hoʻokahi manawa i ka lā, maikaʻi loa i ke kakahiaka me ka meaʻai. Pono ʻia nā ʻūpī, ʻaʻole hiki iā lākou ke pua a ʻāʻā paha.

Inā no kekahi kumu i hala kahi hoʻokipa ʻana, a laila e hoʻokaʻawale ʻia ka hoʻopiha ʻana me ka pākēnē. ʻO ka puhī poina mau ʻia e inu i ke kakahiaka aʻe. ʻO ka helu o ka lāʻau, e like me kēlā me kēia lāʻau hypoglycemic koho, koho mau ʻia no kēlā me kēia kanaka e like me kāna hōʻike ʻana e pili ana i ka glucose o ke koko a me ka hemoglobin pae.

ʻO ka dosent i hoʻomaka ʻia e 30 mg i kēlā me kēia lā. Ma hope, hiki ke hoʻoponopono ʻia i 60, 90 a me 120 mg. Hoʻonohonoho ʻia e hoʻonui i nā ʻano o nā lā i kēlā me kēia lā i hoʻokahi mahina ma hope o ka hopena mua. ʻO nā mea ʻē aʻe kekahi nā hihia i hāʻawi ʻole ʻia ai ka hopena mua loa i ka hopena i manaʻo ʻia, a noho mau ka glucose i ka pae like (ma mua o ka ʻoihana). I kēia kūlana, hiki ke hoʻonui ʻia ka dosage ma mua - ma hope o 14 lā.

HF me ka mālama mālamaʻana he 30-120 mg.

Inā pono e hoʻokaʻawale i ka mea maʻi me Glidiab 80 mg i nā lāʻau lāʻau me ka hana lōʻihi (MV 30 mg), e hana ʻia ma hope o ka loiloi ʻana i ka pae o ka glucose ma kahi hoʻohālike o 1: 1. Inā lawe mua ka mea maʻi i nā lāʻau lapaʻau hypoglycemic ʻē aʻe, a laila pono e hoʻoneʻe me ka helu ʻana o ka lāʻau HF ma mua a me ka manawa o kona lawe ʻia ʻana. ʻAʻohe mea e pono e nānā i ka manawa o ka loli, ʻo ka SN mua o ka Glidiab MV he 30 mg ma hope, hiki ke hoʻololi ʻia.

Inā ua lawe i ka mea maʻi i nā pōpoki me kahi manawa lōʻihi o ka excretion o ka mea hana ikaika, pono e hoʻokaʻawale kahi pale e pale ai i kahi hopena hoʻohui. Ma hope o kēia, hiki iā ʻoe ke hoʻomaka e lawe i kahi lāʻau lapaʻau lōʻihi me ka hana o ka lā he 30 mg.

ʻAʻole koi ʻia ka hoʻoponopono ʻana o nā Doseage e nā makahiki no nā maʻi maʻi (65+). No ka poʻe kūleʻa, hoʻolahalaha ʻia ʻo 30 mg o CH.

I ka paleʻana o nā hoʻopiʻi o ka maʻi diabetes, hiki ke hoʻonui ʻia ka nui o ka lā i kēlā me kēia lā nui o ka 120 mg ma ke ʻano he nui no ka ʻai ʻana a me ka hana kino. Hoʻopau ʻia ka ʻike a hiki i nā hōʻailona ke hoʻomaʻamaʻa maʻamau, e noʻonoʻo ana i ka hopena o ka hypoglycemia.

Ma ka hāpai ʻana, HB

He mea pono ʻole ia no ka wahine e hoʻohana i nā lāʻau kūlohelohe e hoʻohaʻahaʻa i ke kahe koko i loko o ka wā e hānau ai kahi keiki, no ka mea ʻaʻohe kumu o ka palekana o Glidiab MV.

No ka hoʻomākaukau no ka hāpai a i ka wā e kū kūʻē ai i ke ʻano o ke papa o nā papa o Glidiab MV, pono e kāpae ʻia ka lāʻau lapaʻau a pono hoʻi e kuhikuhi ʻia ka wahine ma ka ʻomo ʻana i ka insulin.

ʻAʻohe mea hilinaʻi e pili ana inā e hoʻoheheʻe ʻia ka mea ikaika i ka waiū umauma, no laila, he mea kūpono loa ia e hoʻohui i nā lāʻau lapaʻaka hypoglycemic me ka lactation. I ka manawa e lawe ai i nā papa HB, pono e hoʻopau ʻia ia i mea ʻole e hoʻonāukiuki i ka emi ʻana o ke kaila koko i loko o ke keiki.

Nā pili kūleʻa lāʻau

I ka wā o ka mālama ʻana me nā papa Glidiab MV, pono e noʻonoʻo ka mea e hiki ai i ke gliclazide me nā mea kanu o nā lāʻau ʻē aʻe.Hiki i ke kūlohelohe hiki ke hoʻohui pū me nā lāʻau lapaʻau e hoʻoikaika i ka hopena o gliclazide, no ka mea i hoʻonui ʻia i ka hoʻoweliweli o ka hypoglycemic coma.

Ke papa ʻole loa ia e hoʻohui i ka hoʻolaʻa ʻana o Glidiab MV me Miconazole (systemic a externally or form of a gel), no ka mea, ua hāʻawi kēia i kahi mea hōʻeha kino, kahi hiki ke make.

ʻAʻole ia e hāʻawi i hoʻohui i ka lāʻau me ka phenylbutazone no ke kumu like. Pono e hoʻololi pono i kekahi lāʻau lapaʻau anti-inflammatory. Inā hiki ʻole ke kāpae ʻia, pono e ʻike ka mea maʻi i nā hopena e hiki mai ana a me ka pono o ka mālama mau ʻana i ka glucose i loko o ke koko.

Ua papa ʻia ia e hui pū me nā inu kīʻaha a me nā mea kanu, no ka mea e hoʻōla ʻo ka waiʻona i ka hoʻomohala ʻana i ka coma hypoglycemic com.

Nui nā lāʻau lapaʻau i hiki ke kuhikuhi ʻia me ka mālama akaʻa pū me ka Glidiab MV. Kēia mea kanu lāʻau i ka insulin, metformin, alpha-glucoside inhibitors, beta-blockers, sulfonamides, NSAIDs, etc. A inā e pono, e nānā pono ʻia kā lākou hoʻohana no nā hōʻailona makemake ʻole.

Hoʻopili ʻo Danazole i kahi hopena maʻi maʻi, palupalu i ka hopena o ka glycationis, a hāʻawi i kahi hoʻonui o ke kao o ka glucose i loko o ke koko. Inā ʻaʻole hiki ke hoʻololi hou i ka lāʻau lapaʻau me kekahi lāʻau lapaʻau ʻē aʻe, pono e hoʻomau ka hoʻomau i ka maʻi o ke kō, inā pono, pono ke hoʻoponopono ʻia ka nui o ka Glidiab MV.

Hoʻonui ka Chlorpromazine i ka hoʻokahe koko a hoʻoemi i ka synthesis o ka insulin. ʻO ka hoʻomau mau ʻana o ka kō i ka maʻi maʻi ma mua o ka maʻi me ka hoʻonaninani, kahi mālama akahele o ka nui o ka gliclazide me ka hoʻohana pū ʻana o Glidiab MV i ka wā mālama me Chlorpromazine a ma hope o kona haʻalele ʻia.

Hōʻalo i nā corticosteroids me kekahi mau ʻano o ka noi (waho, kūloko, intravenous a rectal) e hoʻonui i ka kukuna o ka glucose a e kōkua i ka ulu ʻana o ka ketoacidosis. Ke hui pū ʻia me kēia ʻano lāʻau lapaʻau, mālama ʻia ka mālama pinepine ʻana i ke kōhi koko a pono ia e noʻonoʻo pono i ka palekana palekana ma ke ʻano o ka manawa like a ma hope o ka pau ʻana o ka therapy hormonal.

Me ka papa hana me nā anticoagulants, hiki ke hoʻonui i kā lākou hana. Pono ʻia ke hoʻoponopono ʻana.

Nā hopena hopena

ʻO ka lawe ʻana i nā papa Glidiab MV hiki ke hele pū me nā ʻano maikaʻi o ke kino.

E like me nā lāʻau āpau o ka pūʻulu sulfonylurea, hiki i ka lāʻau lapaʻau ke hoʻonāukiuki i ka hypoglycemia inā lawe ʻia nā papa i ka manawa maʻamau a maʻamau loa me nā kīʻaha. I kēlā mau kūlana, e hele pū ʻia ke ʻano me ka:

• Nā Aliʻi
• Pololi loa
• ʻAno, nā ʻohu o ka luaʻi
• Pāʻeha
• Lawa a lulu paha
• ʻO ka huhū nui
• Mahalo nui
• Hōʻikeʻike o nā hopena
• Hoʻopiʻi
• Hoʻokuhi ʻia
• Ka ʻike o ka naʻau, ka ʻōlelo a me ka ʻike
• ʻʻAla
• Nā uhi momona
• Ewa ana ka waha
• Delirium
• I nā hihia koʻikoʻi, hiki ke nalowale ka ʻike me ka coma a ma hope paha.

Eia kekahi, ʻike ka mea maʻi i nā ʻano ʻē aʻe:

• Hoʻonui kaho
• ʻIli nā ʻili
• Hoʻopau ʻo BP
• Tachycardia
• Naona Aria
• ʻAniha pectoris.

I nā kumu ʻē aʻe, lawe ʻia nā papa e hoʻohui pū me nā ʻano like ʻole o kekahi mau kino:

• ʻO ka hōʻiliʻili o ka maʻi a me ka hōʻeha, ka wāwae o ka luaʻi, ka ʻōpū o ka ʻōpū, ʻeha a i ke constipation paha. No ka hōʻalo ʻana i nā kūlana i makemake ʻole a hōʻemi paha i ko lākou ikaika, kauoha ʻia nā papa e lawe ʻia me ka meaʻai.
• ʻIli: rashes, itching, Edema's edema, erythema, bullous reaksi.
• Hematopoietic mea ola: anemia, leukopenia, thrombocytopenia. Kūpae ʻia nā kūlana: kau lākou ma luna o kā lākou iho ma hope o ka hoʻopau ʻana i ka lāʻau.
• Hālohola: hoʻōla o nā hui ʻana, ma nā hihia liʻiliʻi - hepatitis. Inā aia nā hōʻailona o ka jaundice cholestatic, a laila pono e hoʻopau ʻia ka lāʻau maʻi.
• Nā Organs o ka hihiʻo: ka hoʻohaʻahaʻa i ka acuity ʻike maka (ʻo ka pinepine ka hanana i ka hoʻomaka ʻana o ke papa ma muli o nā loli i ka glucose).

ʻO nā hopena ʻē aʻe i hōʻike ʻia e pili ana i ka hoʻomākaukau o ka sulfonylurea:

• Erythropenia
• Anemia
• ʻO Vasculitis
• Hyponatremia
• ʻO Agranulocytosis.

Nā kuleana a me nā kūlana e waiho ai

ʻO Glidiab kahi lāʻau lapaʻau lapaʻau.

E mālama i nā papa i kahi maloʻo, hiki ʻole i ka makika a me ka la, i kahi wela a hiki i 25 ºС. Kumuhana i kēia mau kūlana, ʻo 4 mau makahiki o ka noho pu ma ka honua ʻo Glidiab, a ʻo Glidiab MV he 2 mau makahiki.

Loaʻa kahi hewa i loko o ka kikokikona? Koho ia a kaomi Ctrl + Enter.

ʻO ke kumuhana o ka lāʻau lapaʻau

Loaʻa ka lāʻau lapaʻau no ka mālamaʻana i ka maʻi "momona" o ka lua ma ka puka papa, ʻo ke kumu nui o ka lāʻau lapaʻau ka glyclazide. Ka hoʻonohonoho pono o nā papa i nā hoʻohui hoʻohui - microcrystalline cellulose, magnesium stearate a me nā mea ʻē aʻe.

ʻO ka pōkole ʻo "MV", loaʻa i ka inoa o ka lāʻau lapaʻau, kū no ke hoʻokuʻu hou ʻia. Hōʻike nā loiloi o nā kauka e hiki i kēia nuance ke lawe iā ʻoe i ka lāʻau i hoʻokahi manawa i ka lā.

ʻO ka mea nui i ka wā o ka hoʻoulu ʻana e kōkua i ka hoʻoulu ʻana i ka hana o ka muscle glycogen synthetase a me ka hana ʻana o nā wina i ka hormone i loko o ke kino. Eia kekahi, ʻo ka mea nui e hoʻoholo i ka hana huna o ka insulin i ka kō o ke kō, e hiki ana i ka hoʻonui ʻana i ka naʻau ma ka pae o ka cellular.

ʻAʻole ia he mea nui loa ka mea kōkua o nā papa a Glidiab e hōʻemi i ka kikowaena ma waena o ka hoʻohana ʻana i ka meaʻai a me ka hoʻomaka ʻana o ka hana ikaika o ka insulin. Hōʻike ka hōʻike i ka lāʻau e hoʻōla i ka hoʻohanaʻana i ka lāʻau lapaʻau i ka pae kiʻekiʻe o ka mokuahi hyperglycemic, ʻoiai ke hoʻi hou nei i ka pae o ka pae o ka hana o ka hormone.

Loaʻa nā mea āpau o luna e pili ana i ka metabolism a me ka microcirculation. ʻO ka hoʻohanaʻana i ka lāʻau lapaʻau Glidiab e hōʻemi i ka hopena o ka hoʻomohala ʻana i nā loli atherosclerotic i loko o nā moku koko.

Ma muli o nā mea kakaʻī o ka ʻano dosage, ʻo kahi ʻae i hoʻokahi manawa i kēlā me kēia lā e hōʻoiaʻiʻo i ka hopena o ka therapeutic koʻikoʻi o ka mea ikaika i ka plasma no 24 mau hola.

ʻAoʻi no ka hoʻohana ʻana i nā papa

ʻO ka haʻawina o ka lāʻau Glidiab MB hōʻike ʻia ka lāʻau lapaʻau e pono ai no ka mālama ʻana i ka maʻi mellitus i ka hui me kahi meaʻai haʻahaʻa-haʻahaʻa a me ka hana kino olakino maikaʻi loa.

Pēlā i ke kānāwai, hana mau ka lāʻau lapaʻau ʻo ia wale nō ke ʻano o ka hoʻohaʻahaʻa i ke kō koko. ʻO nā hihia kūʻokoʻa wale nō ke hiki ke mālama ʻia i ka mālama paʻakikī ʻana o ka maʻi. Eia ka laʻana, i ka hui pū me nā hoʻomākaukau mai ka pūʻulu biguanide.

ʻO ke ʻano o ka lāʻau lapaʻau e kuhikuhi ʻia e pili ana i nā kuhikuhi o ke kō o ka honi ma luna o kahi ʻōpū, a i ʻelua mau hola ma hope o ka pāʻina.

Ma Glidiab, nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana i kēia mau ʻike:

1. Hoʻololi ʻia nā papa e lawe ʻia i hoʻokahi manawa i ka lā, ʻo ka manawa kūpono loa ʻo ke kakahiaka ma mua o ka ʻai ʻana.
2. I ka awelika, ʻo ka maʻi pākahi i kēlā me kēia lā he 80 mg, mau no nā maʻi maʻi (ma luna o 65).
3. Inā lawa ka hopena therapeutic, e ʻae ʻia i hiki ke hoʻonui i ka dosage me ke anelē o 14 lā.
4. ʻAʻoleʻoi aku ka nui o ka nui ma mua o ka lā ma mua o 320 mg.

Inā heleʻole ka mea maʻi i ka ate a me ka hana o ka lāpō, a laila ʻaʻole pono ka hoʻoponopono ʻana o ka dosis i ka lāʻau Glidiab MV.

ʻO ke kumukūʻai o ka lāʻau lapaʻau, kahi o ka nui o ka waihona o 80 mg (60 papa no ke pākeke) he 134 mau rubles. ʻO ke kumu kūʻai o nā papa 60 i kahiʻu no 30 mg ka 130 rubles. Uaʻoi aku ke kumukūʻai o Glidiab MB no ke kumu kūʻai, ʻo ke kumukūʻai no 60 pcs. 80 mg i kēlā me kēia he 185 rubles.

Nā hiʻohiʻona o ka lāʻau

I kahi kūlana, ʻaʻole i aʻo ʻia e Glidiab e kuhikuhi ma muli o ka hiki ʻana o nā contraindications, ka nui o ka hoʻonāukiukiʻana i nā hōʻeha mai ke kikowaena pūnaehana sentral a me nā ʻōnaehana cardiovascular.

I kēia hihia, ua noi ʻia nā lāʻau like ʻole. ʻO nā mea kikoʻī no Glidiab nā: Formin, Amaryl, Diabrex, Maninil, Glurenorm a me nā lāʻau ʻē aʻe no ka mālamaʻana i ka maʻi maʻi.

Ke loli ʻana i ka lāʻau lapaʻau me kekahi lāʻau lapaʻau ʻē aʻe pono e alakaʻi ʻia e nā kauka hele mai, ʻaʻohe mea ʻē aʻe.

E noʻonoʻo pono i nā mea kikoʻī:

• ʻO ka formmetin kahi lāʻau lapaʻau i hāʻawi ʻia no ka mālama ʻana i ka maʻi type 2 no ka mea i hoʻomaʻamaʻa ʻole ke ʻano o nā meaʻai. Hoʻomaopopo pinepine ʻia i ka hui pū me nā lāʻau lapaʻau e pili ana i ka sulfonylurea.
• ʻO nā papa maninil ka papa kīnā nui o ka glibenclamide, nā derivatives o ka sulfonylurea. Hoʻokumu ka lāʻau lapaʻau i ka hana ikaika o ka insulin, e hāʻawi i kahi hopena o ka insulin-excreting o ka glucose.
• Hoʻololi ʻia ʻo Glibenclamide no ka lua o ke ʻano maʻi maʻi ʻalani, i ka wā hiki ʻole ke uku ʻia no ke ʻano o ka patology ma o kaʻaiʻai a me ka haʻuki. Kuhi ʻia ka nui ma ke ʻano o nā kuhikuhi gula, hiki ke hoʻololi ʻia mai ka 2,5 a 15 mg. Hoʻohui pinepine ʻana i ke noi ʻana i nā manawa i kahi lā.
• Amaryl - kahi maʻi hypoglycemic, i kuhikuhi ʻia no ka mālama ʻana i ke ʻano o ka lua o ka maʻi i mea wale nō ke ʻano o ka lāʻau ʻona a i hui pū ʻia me insulin a me metformin paha. Ma ke ʻano he kānāwai, lawe ʻia nei ka lāʻau me kēia lāʻau lapaʻau no ka manawa lōʻihi.

ʻO ka lāʻau ʻo Glidiab a me kāna mau kikowaena kūpono loa i ka mālamaʻana i ka maʻi "ʻoluʻolu". Eia naʻe, me kahi waiwai maikaʻi, loaʻa lākou nā contraindications a me nā hopena hopena. No laila, pono ke kuʻina i kahi manawa e ke kauka.

Mālama i nā paila e kōkua i ke kino e hōʻemi i nā kiʻekiʻe o ka glucose a hoʻopaʻa mau iā lākou ma ka pae e pono ai. Akā, i mea e hoʻonui ai i ka hiki i ka hoʻohana pono ʻana i nā lāʻau lapaʻau, pono ka mea maʻi e pili pono i kahi meaʻai a hoʻomaʻamaʻa e hoʻonui ai i ka ʻike ʻana i nā kiko palupalu i ka glucose.

He aha kāu manaʻo e pili ana i kēia? He aha nā lāʻau lapaʻau i kuhikuhi ʻia e kāu kauka, a he aha kāu e haʻi ai mai kēlā me kēia mai nāʻike o kouʻike?