He aha ka wehewehe o ka acromegaly, nā hōʻailona, pale i ka maʻi

Hāʻawi mākou iā ʻoe e heluhelu i ka ʻatikala ma luna o ke kumu: "he aha ka wehewehe acromegaly, nā hōʻailona, ka pale ʻana i nā maʻi" me nā ʻōlelo mai nā poʻe akamai. Inā makemake ʻoe e nīnau i kahi nīnau a kākau paha i nā ʻōlelo, e maʻalahi ʻoe i kēia ma lalo o ka ʻatikala. ʻO kā mākou loea endoprinologist e ʻike maoli iā ʻoe.

Acromegaly - ke hoʻonui ʻana o ka pathological i kekahi mau wahi o ke kino e pili ana me ka hoʻonui nui ʻana o ka ulu ulu ʻana (hormone ulu) e nā aniani pituitary mua ma muli o kāna kōkō. ʻIke ʻia i nā pākeke a hōʻike ʻia e ka nui o nā hiʻohiʻona helehelena (ihu, pepeiao, mau lehelehe, ʻōpū lalo), ka nui o ka wāwae a me nā lima, nā kuʻuna o ke poʻo a me nā ʻōpū kuʻuna, nā hana moekolohe a hana hou i nā kāne a me nā wahine. ʻO ka pae kiʻekiʻe o ka ulu ulu ʻana o ke koko e hoʻomaka ai ka make ma mua mai ke kanesa, pulmonary, nā maʻi cardiovascular.

Wikiō (kaomi ke pāʻani).

Hoʻomaka ka Acromegaly e ulu ma hope o ka pau ʻana o ka ulu kino o ke kino. ʻOi aku ka lōʻihi, ma ka manawa lōʻihi, nui nā hōʻailona, a me nā loli o ka helehelena. I ka awelika, ʻike ʻia ka acromegaly ma hope o 7 mau makahiki mai ka hoʻomaka ʻana o ka maʻi. Hoʻonui ʻia ka maʻi i waena o nā wahine a me nā kāne, ma ka nui o nā makahiki 40-60 mau makahiki. ʻO Acromegaly kahi maʻi endocrine līkia a nānā ʻia ma nā kānaka 40 no kēlā me kēia 1 miliona mau kānaka.

ʻO ka hūnā ʻia o ka ulu ulu ʻana (e ulu ana ka nui o ka ulu ʻana, STH) e ka kelepona pituitary. I ka wā kamaliʻi, ʻo ka ulu ʻana o ka hormone kaohi i nā kaʻina o ka hoʻokumu ʻana o ke aunaʻi musculoskeletal a me ka ulu ʻana o ka laina, a ma nā pākeke ke kāohi nei i ka hoʻoneʻe ʻana mai ka hāmeʻa, momona, wai-paʻakai. ʻO ka mea huna o ka ulu ulu ʻana e hoʻoponopono ʻia e ka hypothalamus, e hana ana i nā neurosecrets kūikawā: somatoliberin (hoʻoulu i ka hana o GH) a me somatostatin (ke kāohi nei i ka hana o GH).

ʻO ka maʻamau, ka liʻiliʻi o ka ʻikepili somatotropin i ke koko i ka wā o ka lā, hiki i kona kiʻekiʻe ma nā hola kakahiaka. I ka poʻe maʻi me ka acromegaly, ʻaʻole wale ka mea e hoʻonui ai i ka kao ʻana o ka STH i loko o ke koko, akā ua pale pū ʻia i ka ritika maʻamau o kāna honi. No nā kumu like ʻole, ʻaʻole mālama nā cell o ke aniani pituitary gland i ka mana hoʻoponopono o ka hypothalamus a hoʻomaka e hoʻonui ikaika. Ke alakaʻi nei i nā hua o ka nā pituitary i ke ʻano o ke koena o ke aena o ke kanalula - he adenoma pituitary, ka mea e ulu ai ka somatotropin. Hiki i ka nui o ka adenoma ke hele i luna o nā kenimika a keu i ka nui o ke aniani ponoʻī, ʻae me ka luku ʻana i nā cell pituitary maʻamau.

Ma 45% o nā maʻi me ka acromegaly, hoʻōla wale ʻia nā mea hoʻonaninani me kahi somatotropin, he 30% hoʻohui pū kekahi i ka prolactin, ma ke koena 25%, ka hoʻohui, luteinizing, follicle-stimulating, hoʻōla a hoʻoluʻu, hoʻāliʻi ʻia kahi subunit. I loko o 99%, ʻo ia ka adenoma pituitary e kumu ana i ka acromegaly. ʻO nā mea nāna i hoʻomohala i ka hoʻomohala ʻana o ka adenoma pituitary he mau hōʻeha o ka traumatic brain, nā maʻi tumuna hypothalamic, maʻi sinus aitis sinus (sinusitis). Hāʻawi ʻia kekahi kuleana i ka hoʻomohala ʻana o ka acromegaly i ka moʻomeheu, ʻo ka mea i ʻike pinepine ʻia ka maʻi i nā ʻohana.

I ka wā kamaliʻi a me ka ʻōpio, kū i ke kua o ka ulu mau ʻana, ʻo ka maʻi STH hypersecretion e hōʻeha nei i ka gigantism, i hōʻailona ʻia e ka nui, akā nui ka laha ʻana i nā iwi, nā ʻōpū a me nā kiko palupalu. Me ka pau o ka ulu ʻana o ka physiological a me ka ossification o ka ʻōpū, nā pilikia o ke ʻano o ka ulu ʻana o ka acromegaly - disproportionate ka huhū o nā iwi, ka piʻi ʻana o nā kino o loko a me nā mea pili o ka metabolic. Me ka acromegaly, hypertrophy o ka parenchyma a me ka stroma o nā kino o loko: ka puʻuwai, ka māmā, ka pancreas, nā ate, spleen, mau loko. Ke ulu nei ka ulu ʻana o ka kiko konohiki i nā loli o ka sclerotic i kēia mau mea i hoʻonui ʻia, ʻo ka hōʻeha ʻana o ka hoʻomohala ʻana i ka momona benign a me nā laha, me nā mea endocrine ka hoʻonui

Hāʻawi ʻia ka Acromegaly e nā papa lōʻihi, pālua. Mamuli o ka paʻakikī o nā hōʻailona i ka hoʻomohalaʻana i ka acromegaly, aia kekahi mau manawa:

ʻO kahi hana o ka preacromegaly - mua, hele mai nā hōʻailona maʻalahi o ka maʻi. Ma kēiaʻano, ʻike pinepine ʻia ka acromegaly e nā hōʻailona wale nō o nā pae ulu o ka hormone ulu i loko o ke koko a ma o ka CT o ka lolo.
Hōʻike Hypertrophic - i ʻike ʻia nā hōʻailona o ka acromegaly.
ʻO ke ʻano o ke Tumor - nā hōʻailona o ka hoʻopiʻi ʻana o nā ʻāpana o nā ʻōpū o ka lolo (i hoʻonui ʻia ke kaomi intacranial, ka aʻalolo a me nā maka o ka maka) i mua o ke alo.
Stage cachexia - hoʻomaha kahi mea like ka hopena o ka acromegaly.

Hiki ke hoʻohālikelike ʻia o ka acromegaly ma muli o ka nui o ka ulu ʻana o ka hormone ulu a i ʻole ka hana a ka adenoma pituitary ma nā nū optic a me nā hana hoʻāla kokoke.

ʻO ka ulu nui o ka hormone hoʻoulu i ke ʻano o ka hoʻololi ʻana i nā hiʻohiʻona o nā mea maʻi me ka acromegaly: kahi māhuahua o ka iwi haʻahaʻa, nā iwi zygomatic, nā pana o ka superciliary, hypertrophy o nā lehelehe, ka ihu, nā pepeiao, e alakaʻi ana i ka hoʻopiʻi ʻana o nā hiʻohiʻona. Me ka hoʻonui ʻana o ka maʻa haʻahaʻa, aia ka ʻokoʻa i ka laha kikowaena a me ka hoʻololi ʻana o ka ʻuʻū. Aia ka hoʻonui i ka ʻōlelo (macroglossia), kahi i paʻi ʻia ai nā hōʻailona niho. Ma muli o ka hypertrophy o ka alelo, laring a me nā kaula kīʻaha, ua loli ka leo - e lilo a haʻahaʻa a hina. Hoʻololi pinepine ʻia nā loli ma ke ʻano me ka acromegaly, hiki ʻole i ka mea maʻi. Aia kahi mānoanoa o nā manamana lima, ka nui o ka nui o ka ʻōpū, nā wāwae a me nā lima a i ʻole ka mea maʻi e koi ʻia i nā pāpale, nā kāmaʻa a me nā lima he nui ka nui o ka nui ma mua.

Me ka acromegaly, e hele nei ka deforme skeletal: kuʻi ka kuʻi, ka nui o ka pahu ma ka nui o ka anteroposterior, e loaʻa ana i ke ʻano o kahi pahu, hoʻonui ʻia nā wahi intercostal. ʻO ka hoʻomohala ʻana i ka hypertrophy o ka hoʻopili a me ka cartilage i hoʻopili ai i ka hoʻoneʻe a hoʻololi ʻana i ka hoʻoweliweli hui ʻana, arthralgia.

Me ka acromegaly nui loa, ka lula loa a me ka hoʻohuihui sebum, ua ʻike ʻia, no ka hoʻonui ʻia ʻana o ka nui a me ka hana o ka pulelula a me nā lepa sebaceous. ʻO ka ʻili i nā maʻi me ka acromegaly mānoʻa, mānoʻa, a hōʻuluʻulu i nā lōlō hohonu, keu nui hoʻi i ke poʻo.

Me ka acromegaly, he nui o ka nui o nā ʻōpū a me nā hana o loko (o ka puʻuwai, nā ʻōpū, nā ʻōpū) e hele pū me ka hoʻonui nui o ka dystrophy o nā uaua kinohi. Hoʻomaka ka poʻe maʻi e hopohopo e pili ana i nā nāwaliwali, nā luhi, kahi lohi holomua i ka hana. Hoʻokumu ka myocardial hypertrophy, a laila hoʻololi ʻia ka myocardial dystrophy a me ka hoʻonui ʻana i ka puʻuwai naʻau. ʻO kahi hapakolu o nā poʻe maʻi me ka acromegaly he hypertension arterial, ma kahi o 90% e hoʻomohala ai i ka maʻi ʻĀpana carotid e pili ana me ka hypertrophy o nā kiko ngoʻī o ka ʻōpū hanu o luna a me ka hana a ke kikowaena o ka ʻōpū.

Me ka acromegaly, ʻeha ka hana a ka wahine. ʻO ka hapanui o nā wāhine me ka nui o ka prolactin a me ka nele o nā gonadotropins e hoʻomohala i nā menstrual irregularities a me ka hōʻeha, ʻike ʻia ka galactorrhea - ka hoʻokuʻu ʻana o ka waiū mai nā nipples, ʻaʻole i hoʻokumu ʻia e ka hapai a me ka hānau ʻana. 30% o nā kāne he ʻoki i loko o ka palupalu male. Hōʻike ʻia ka hyposecretion o ka lāʻau antidiuretic me ka acromegaly e ka hoʻomohala ʻana o ka maʻi insipidus maʻi.

Ke ulu nei ka ʻoi a me ka pulupulu o ka puluitary e hoʻoulu ʻia ai nā aʻaloko a me nā umauma, aia ka nui o ka hoʻoulu ʻana i ka intracranial pressure, photophobia, pālua papalua, ʻeha i ka ʻāʻī a me ka lae, ka dizziness, ka luaʻi, hōʻemi ka lohe a me ka ʻono, hoʻonaninani o nā wāwae. I nā mea maʻi e loaʻa ana i ka acromegaly, ʻo ka hopena o ka ulu ʻana o nā ʻōpū o ka kelepa thyroid, hoʻonui i nā hui o ka pēpē o gastrointestinal, a me ka ʻōpū o ka ʻōpū.

ʻO ke papa o ka acromegaly pū kekahi me ke kūkulu ʻia ʻana o nā hoʻopiʻi mai nā aneane āpau. ʻO ka mea maʻamau i nā maʻi me ka acromegaly he naʻau hypertrophy, myocardial dystrophy, hypertension arterial, hōʻeha puʻuwai. ʻOi aku ma mua o kahi hapakolu o nā maʻi e hoʻomohala i nā maʻi mellitus, ate dystrophy a me ka pulmonary emphysema i nānā.

ʻO ka hānai ʻana i nā mea e ulu ai me ka acromegaly alakaʻi i ka hoʻomohala ʻana o nā hakahaka o nā ʻano ʻano ʻē aʻe, ʻo benign a me nā hewa hoʻi. ʻO ka Acromegaly hele pū me ka diffuse a i ʻole nodular goiter, fibrocystic mastopathy, adenomatous adrenal hyperplasia, polycystic ovaries, uterine fibroids, intestinal polyposis. Ke hoʻomohala ʻana i ka lawa o ka pituitary (panhypopituitarism) ma muli o ke koi a hoʻoneʻe a me ka hoʻoulu ʻana o ka aihini pituitary.

I nā manawa ma hope (5 mau makahiki ma hope o ka hoʻomaka ʻana o ka maʻi), hiki ke hoʻāʻo ʻia ka acromegaly ma ke kumu o ka hoʻonui ʻana o nā ʻāpana o ke kino a me nā hōʻailona ʻē aʻe e ʻike ʻia i ka wā o ka hoʻokolokolo. I kēlā mau hihia, ʻōlelo ka mea maʻi no ka kūkākūkā ʻana e nā endocrinologist a me nā hoʻokolohua no nā diagnostics laboratorium.

ʻO nā ʻōnaehana hana nui no ka ʻikeʻana i ka acromegaly ka hopena o ke kō o ke koko:

ka ulu ʻana o ka hormone i ke kakahiaka a ma hope o ka hoʻāʻo ʻana o ka glucose,
IRF I - nā ulu ulu like-insulin.

Hoʻololi ʻia ka hoʻonui ʻana i ka pae o ka holomua hormone i ke kokoke ʻana o nā maʻi āpau me ka acromegaly. ʻO ka hōʻike waha ma ka ukana glucose i ka wā acromegaly pili i ka hoʻoholo ʻana o ka waiwai mua o STH, a ma hope o ka lawe ʻana i ka glucose - ma hope o ka hapalua hola, hola, 1.5 a me 2 mau hola. Ma keʻano maʻamau, ma hope o ka lawe ʻana i ka glucose, ua emi ka pae o ka ulu ʻana o ka hormone ulu, a me ka hana o ka acromegaly, ma ke ʻano ʻē, ʻike ʻia kona hoʻonui. Hōʻikeʻike maoli ka hōʻike ʻana i ka glucose i nā hihia o ka hoʻonui ʻana i ka pae o STH, a i ʻole nā waiwai maʻamau. Hoʻohana ʻia kahi hōʻike hoʻonaninani glucose e nānā i ka pono o ka hana acromegaly.

Ke hana nei ka hormone ulu i ke kino ma o nā mea ulu like-like insulin (IRF). Hōʻike ka plasma plasma o ko IRF i ke ʻano o ka hoʻokuʻu ʻana o GH i kēlā me kēia lā. ʻO ka hoʻonui ʻana ma IRF I i ke koko o kahi pākeke hōʻike pololei i ka hoʻomohala ʻana o ka acromegaly.

I ka wā o ka hoʻokahuli o ka ophthalmological i nā poʻe maʻi me ka acromegaly, ua ʻike ʻia kahi mānoʻina o nā kula ākea, no ka mea, aia nā ala kime anatomically i loko o ka lolo e kokoke ana i ka lula pituitary. Ke hōʻike ʻia nei ka kahe ʻana o ka iwi ʻōpala i ka nui o ka nui o ke kanikani Turkish, kahi i loaʻa ka kelepona pituitary. Ke ʻike nei i ka maʻi o ka pituitary, nā kamepiula diagnostics a me MRI o ka lolo e hana ana. Eia kekahi, ua nānā ʻia nā mea maʻi me ka acromegaly no nā hoʻopiʻi like ʻole: polyposis intestinal, diabetes mellitus, goiter multinodular, etc.

Ma ka acromegaly, ʻo ka pahuhopu nui o ka mālama ʻana, ʻo ia ka hōʻea i ke kala ʻana i ka maʻi ma o ka hoʻopau ʻana i ka somatotropin hypersecretion a me ka hoʻōla ʻana i ka ʻike o ka IRF I. No ka mālama ʻana i ka acromegaly, hoʻohana ka endocrinology hou e pili ana i ka lāʻau lapaʻau, ka haukapila, ka radiation a me nā ʻano hui.

E hoʻolaʻa i ka pae o ka somatotropin i ke koko, ua kuhikuhi ʻia ke alakaʻi o nā mea hoʻohālike a somatostatin - kahi neurosecret o ka hypothalamus e kāohi ana i ka hana huna o ka hormone ulu (octreotide, lanreotide). Me ka acromegaly, ua hōʻike ʻia ke koho ʻana i nā hormones sex, dopamine agonists (bromocriptine, cabergoline). ʻO ka hopena, ke hana pinepine ʻia nā gamma hoʻokahi a me nā hanana radiation i ka kelepona pituitary.

Me ka acromegaly, ʻo ka ʻoi loa ka hoʻomaʻamaʻa ʻana i ka maʻi hōʻola ma ke kumu o ka wahī ma o ka iwi sphenoid. Me nā adenomas liʻiliʻi ma hope o ka hōʻoki ʻana, ua hōʻemi ʻia ka nui o nā maʻi o ka 85% o nā mea maʻi a me ke kala mau ʻana o ka maʻi. Me kahi wīwī koʻikoʻi, hiki i ka pakeneka o ke lapaʻau ma muli o ka hana mua ma ka 30%. ʻO ka make miki no ka hoʻomaʻamaʻa ʻana o nā acromegaly mai 0.2 a 5%.

ʻO ka nele o ka mālama ʻana no ka acromegaly e alakaʻi i ka pilikia o nā mea maʻi o nā makahiki ikaika a me ka hana, hoʻonui i ka nui o ka make ma mua. Me ka acromegaly, ua hoʻemi ʻia ka manaolana: 90% o nā mea maʻi e ola a hiki i 60 mau makahiki. Hoʻā pinepine ʻia ka make ma muli o ka maʻi o ka maʻi maʻi. ʻOi aku nā hopena o nā hana lapaʻau o ka acromegaly me ka liʻiliʻi o nā adenomas liʻiliʻi. Me nā nunui o ka kelepona pituitary, ʻo ke alapine ʻana o kā lākou mau kahe e hoʻonui mālie.

I mea e pale ai i ka acromegaly, pono e pale ʻia nā hōʻeha o ke poʻo, a pono e hoʻomaʻemaʻe ʻia ka ʻoi ʻana o ka maʻi nasopharyngeal. ʻO ka ʻike maka mua o ka acromegaly a me ka normalization o nā kiʻekiʻe hormone ulu e kōkua i ka pale ʻana i ka hoʻopiʻi ʻana a hoʻomau i ke kala mau ʻana o ka maʻi.

ʻO ke kumu a me nā ana o acromegaly

Hoʻokomo ka kelepona pituitary i ka hormone somatotropic (STH), nona ke kuleana no ka hoʻokumu ʻana i ke kākala musculoskeletal i ke wā kamaliʻi, a i nā pākeke ke nānā i ka metabolism wai-paʻakai.

I ka poʻe maʻi me ka acromegaly, aia ka hewa o ka hana o kēia hormone a me ka hoʻonui i kona piʻi ʻana i loko o ke koko. Hoʻopuka ka adenoma pituitary me ka acromegaly me ka tupu o nā sela pituitary.

Wahi a nā poʻe loea, ʻo ke kumu maʻamau o ka acromegaly kūpono loa i ka adenoma pituitary, hiki ke hana i ka hele ʻana o nā maʻi hypothalamic, hōʻeha ke poʻo, a me ka sinusitis maʻi maʻamau. He hana koʻikoʻi i ka hoʻomohala o ka acromegaly e ka mea hoʻohele no ka hoʻoilina.

Hoʻohālike ʻia ka Acromegaly e ke aʻo lōʻihi, ʻike ʻia kāna mau hōʻike ma kahi pae hoʻomohala:

Hōʻike ʻia ka Preacromegaly e kahi liʻiliʻi iki i ke kiʻekiʻe o ka GH, ma muli o kahi e hoʻomaʻamaʻa ʻole ʻia nā hōʻailona o ka hōʻike ʻana o ka pathology,

Hypertrophic stage - ʻike ʻia nā hōʻailona o ka maʻi.

Hoʻomaʻamaʻa ka pae ʻōpala i ka hoʻonui ʻia o ka pume intracranial a me nā haunaele i ka hana o ke ʻano ʻike a me ka ʻōnaehana,

Cachexia - nānā ʻia ke ahonui.

Ma muli o ka hoʻomohala lōʻihi i ka hana mua o ka acromegaly, ʻaʻohe hōʻailona o nā ʻaoʻao o waho.

Nā hōʻike haukapila

Nā hōʻailona kumu o ka acromegaly i loko o nā keiki a me nā pākeke:

ʻO ka ʻeha i loko o ka pōkole spinal a me nā hana ma muli o ko lākou destabilization a me ka hoʻomohala ʻana i ka lāʻau arthropathy,

ʻO ke kapa kāne ākea i ka wahine,

ʻO ka hoʻonui ʻia o nā wahi ma waena o nā niho, ka hoʻonui ʻana i nā ʻāpana like ʻole o ka maka, ka ʻala ʻana o ka ʻili.

Nā hiʻohiʻona o nā ulu kūloko.

ʻO ka hoʻonuiʻana thyroid,

Hoʻemi i ka hana e hana, luhi.

ʻO ka hoʻomohala ʻana o nā ala cardiovascular hiki ke alakaʻi i ka make,

Hoʻokumu i ka maʻi maʻi

Hōʻea ka hoʻonāukiuki o ka ʻili,

ʻO ka hoʻopauʻana o ka pūnaehana hanu.

Me ka acromegaly pituitary, ʻo ka hoʻoulu ʻana o nā pūleo maikaʻi e kū mai ana, e hoʻonāukiuki ai:

Hoʻopau i nā mālamalama a me nā libido i nā kāne,

Hōʻailona, nā menstruation i nā wahine,

ʻO nā migraines pinepineʻole i nā mea hiki ʻole i nā lāʻau lapaʻau.

Diagnosis

Hiki i ka hoʻomohala ʻana o ka acromegaly a me ka gigantism ma ke kumu o ka ʻikepili: ka lolo MRI, nā hōʻailona, ka radiation o ka wāwae, nā ʻōhua biochemical.

Ma waena o nā haʻawina hoʻokolohua, hoʻokaʻawale ka hoʻokaʻawale ʻana o ke kukuna o ka STH a me ka like me ka ulu ʻana o ka inika-1. ʻO ka maʻamau, ʻoi aku ka pae o STH ma mua o 0.4 μg / l, a me ka IRF-1 e kuhikuhi i nā kuhikuhi kumu e like me ke ʻano o ka wahine a me ka makahiki o ke kumuhana. Me nā hana ʻino, ʻaʻole hiki ke hoʻokele ʻia ka noho ʻana o ka maʻi.

Hoʻonohonoho ʻia ka hoʻonā ʻia o ka wāwae e nānā i ka mānoanoa o kāna mau ʻili nāu. ʻO nā waiwai kumu i nā kāne a hiki i ka 21 mm, i ka wahine - a hiki i 20 mm.

Inā hoʻokomo ʻia ka maʻi, ka noiʻi o ka pathogenesis o ka acromegaly a me ka hoʻoholo ʻana o nā hana hoʻopunipuni i ka pituitary a me hypothalamus.

Hoʻohui ʻia ka pākuʻi ʻana o nā ʻōpū pelvic, umauma, retroperitoneum, a me nā mea mediastinal i ka ʻole o nā pathuitary pathologies a me ka hōʻike ʻana o nā biochemical a me nā hōʻike maʻi o ka maʻi acromegaly.

Therapeutic kaʻina no ka acromegaly

ʻO ka pahuhopu nui o nā ʻano therapeutic no kēlā me ke ʻano kīpē ʻana o ka hoʻohālikelike i ka ulu ʻana o ka ulu ulu ʻana, ʻo ia hoʻi, e lawe nei i kahi kūlana o ke kala ʻana.

No kēia, ua hoʻohana ʻia nā ʻano ʻoi aʻe nei:

Hoʻohana ʻia ka lāʻau maʻi ma loko o nā ʻano ʻelua: transcranial a me transgenic. ʻO ke koho e hana ʻia e kahi neurosurgeon. Hoʻohana ʻia ka hoʻomaʻamaʻa ʻana e wehe i ka microadenomas a i ʻole ʻāpana wehe ʻana i nā macroadenomas.

Hoʻolaha ʻia ka ʻike maka i ka haʻalele ʻana o ka hopena ma hope o ka hiki ʻana i ka lāʻau lapaʻau, no ka mea ʻo kēia gamma knives, kahi beahi proton, hiki ke hoʻohana ʻia ka linear.

I loko o ka lāʻau lapaʻau, hiki i nā pūʻulu o nā lāʻau lapaʻau ke hoʻohana ʻia: antatots hormone antatopropic somatotropic, nā somatostatin analogues, nā lāʻau dopaminergic.

Hoʻohana ʻia ka ʻano lāʻau lapaʻau e like me nā ʻōlelo a ke kauka.

ʻO ka koho o nā kaʻina therapeutic e pono e hana i ka hui pū me kahi loea i aʻo ʻia i ka pathogenesis o acromegaly, nā hōʻailona a me nā hopena o nā haʻawina biochemical o ka mea maʻi.

Wahi a nā helu helu, ua manaʻo ʻia ka hana ʻoi ke koʻikoʻi loa, ma kahi o 30% o ka poʻe i hana i ka ho'ōla hou ʻana, a ʻo ke koena he manawa o ka kala mau loa.

No nā mea pale, ua kauoha ʻia:

ʻO ka mālama ʻana i nā maʻi e hoʻopilikia i ka nasopharynx,

Kāohi i nā hōʻeha poʻo.

Inā hele mai nā hōʻailona kānalua, e nīnau aku i ka endocrinologist no ke aʻo ʻana. ʻAʻole pono ke hōʻike pilikino a maʻi ʻē a ʻoi aku ka nui o ka mālama ʻana.

ʻO nā hōʻike kumu o ka acromegaly ma muli o ka hoʻonui ʻana o ka ulu ʻana o ka ulu ulu, kahi ulu ulu kūmole i hoʻohuihui ʻia e ka pituitary gland, a i nā maʻi hoʻi e kumu ai ka hoʻomōhala ʻana i nā ʻōiwi o nā puhipuhī (ʻo ka pituitary adenomas, nā koikoi, nā metastases mai nā kikowaena mamao).

ʻO nā kumu o ka hoʻomohala ʻana o ka maʻi ma ka overproduction o ka hormone somatotropic, ka mea nui ka pituitary i loko o ke ʻano, a i ʻole he kumu hypothalamic.

Hōʻike ʻia ka mana o ke kaʻina pili me ke ʻano o ka wā ʻōpio, ʻo ia kahi manawa i loko o ka wā ʻōpiopio, ka mea i kapa ʻia ʻo gigantism. ʻO kahi hiʻohiʻona hiʻona o ka gigantism i nā keiki ka wikiwiki a me ka proportional i ka ulu ʻana o nā io, nā io, nā iwi ʻoka, nā loli hormonal. ʻO kahi kaʻina like e ulu ana ma hope o ka pau ʻana o ka ulu ʻana o ke kino, i nā makahiki pākeke ua kapa ʻia ʻo acromegaly. ʻO ka manaʻo like ʻia o ka acromegaly i manaʻo ʻia he ʻano disproportionate i loko o nā ʻōpū, nā kiko a me nā iwi o ke kino, a me ka hoʻomohala ʻana i nā maʻi concomitant.

ʻO nā hōʻailona o ka gigantism i nā keiki

Hiki ke ʻike ʻia nā hōʻailona maʻamau o ka acromegaly (gigantism) i nā keiki ma kekahi manawa ma hope o ka hoʻomaka ʻana o kona hoʻomohala ʻana. ʻO waho, ke ʻike ʻia lākou i ka ulu ʻana o nā limahana, ka mea i kū ʻole ʻia a lilo i kaʻaha. I ka manawa like, hiki iā ʻoe ke hoʻomaopopo i ka iwi zygomatic, piʻi nā maka, aia he hypertrophy o ka ihu, ka lae, ka alelo a me nā lehelehe, ma muli o ia ʻano o ke ʻano o nā helehelena, e lilo ana i rougher.

Hoʻonohonoho ka pilikia ma loko o ka edema i loko o nā hana o ka ʻāʻī a me nā sinuses, kahi e hoʻololi ai i ka like o ke kaina o ka leo, me ka haʻahaʻa. Ua hoʻopiʻi kekahi mau maʻi me ka snoring. I ke kiʻi, ʻikea ka acromegaly i loko o nā keiki a me nā ʻōpio i ka ulu nui, ke hoʻonui ʻia ma kahi o nā ʻāpana o ke kino, elongated limahana ma muli o ka hoʻomāke ʻole ʻole o ka iwi. ʻO ka hoʻomohala ʻia o ka maʻi hele pū pū ʻia me nā loli o ka hormonal, nā ʻōuli o kēlā me:

nā ʻōpū o ka hui sebaceous,

hoonui nui i ke kō

kalima ka paʻakai

ʻehā ka hopena o ka hoʻomohala ʻana i ka maʻi ʻōlima,

ʻO ka edema thyroid a me ka hana ʻole.

Hoʻomaʻamaʻa pinepine ʻia i ka wā ʻōpiopio, ka nānā ʻana o ka proliferation o nā kino hoʻohui, ʻo ia ka mea e hōʻike ai i nā puka o ke ʻano a me ka hoʻololi ʻana i nā kino o loko: ka puʻuwai, ka naʻau, ka ʻōpū, nā ʻōpū. ʻO ka pinepine ke ʻike i ke kiʻi o nā keiki i hānau aku me ka acromegaly ʻāʻī, kahi ʻano hiʻohiʻona o ka lending o ka sternocleidomastoid muscle.

Nā hōʻailona o Acromegaly i nā pākeke

ʻO ka hānai ʻana o ka ulu ulu ʻana ke kumu i nā pilikia pathological i loko o ke kino o ka pākeke, ke alakaʻi nei i kahi loli i kona ʻano, hiki ke ʻike ʻia i kāna kiʻi a i ʻole ke kanaka. Ma ke ʻano he kānāwai, ua hōʻike ʻia kēia ma ka ulu maikaʻi ʻana o kekahi mau māhele o ke kino, me ka limu o luna a me nā wāwae i lalo, lima, wāwae, a me kahi ʻūhā. E like me nā kamaliʻi, i nā maʻi maʻi ʻōiwi, ka lae, ka ihu, ke ʻano lehelehe, nā maka, nā iwi zygomatic, ke hoʻololi ʻana o ka iwi haʻahaʻa, ma muli o ka ulu ʻana o ka wahi i waena. ʻO ka hapa nui o nā mea maʻi he macroglossia, kahi hoʻonui hoʻonui pathological o ka alelo.

Nā hōʻailona o ka acromegaly, ka mea i hoʻoili ʻia ma ka hapa nui o ka adenoma pituitary i nā pākeke, ka komo ʻana o ka skeletal deformity, i ka kiko, ka curvature o ka kolone a spinal, hoʻonui ʻia i ka umauma, i ukuhi ʻia e ka hoʻonui ʻia o nā kikowaena intercostal, a me nā loli hui pathological. Hypertrophy o ka cartilage a me ka hoʻohui pili i alakaʻi i kahi kaupalena o ka holo mua ʻana, ka hopena ma ka arthralgia.

Hoʻopiʻi pinepine nā mea maʻi i nā hōʻeha pinepine, nā luhi, nā nāwaliwali o ka naʻau, nā mea i hōʻemi i ka hana. Hoʻopau kēia ma muli o ka piʻi ʻana o ka nui o ka nui me ka degeneration ma hope o nā hua uaua. I ka manawa like, ʻo ka hiʻohiʻona o ka hypocrophy myocardial, ka mea i hala i ka myocardial dystrophy, e waiho ana i ka hoʻolālā ʻana o ka puʻuwai puʻuwai, hiki nō.

ʻO nā maʻi me nā hōʻailona acromegaly e holomua ana e hōʻike pinepine ʻia nā loli i ko lākou helehelena e hoʻohālike ai iā lākou. Eia naʻe, ke nānā nei nā mea kūlohelohe a me nā ʻōnaehana. No laila i nā wahine i hōʻiliʻili ʻia ke kani menstrual, hoʻomohala ʻia ka infertility, galactorrhea - ka hoʻokuʻu ʻana o ka waiū mai nā nipples i ka loaʻa ʻole o ka hapai. Nui nā maʻi, me ka manaʻo o ke kāne a me ke ʻano o ka makahiki, i hōʻike ʻia i ka syndrome apnea moe, ma loko o ka ulana koʻikoʻi e ulu nei.

Inā ʻaʻole i hoʻokaʻawale ʻia, ma ke ʻano he kānāwai, e mau ana ka maikaʻi loa. ʻO ka holomua o nā pilikia pathological e alakaʻi i ka pilikia piha, a ke hoʻonui nei hoʻi i ka pilikia o ka make ma mua o ka hopena o ka maʻi o ka naʻau. ʻO ke ola ola o nā mea maʻi me ka acromegaly maʻi me ka hoʻohaʻahaʻa nui ʻia a ʻaʻole i hiki i 60 mau makahiki.

Nā huapau

He maʻalahi maoli ka hoʻonaninani ʻana i nā acromegaly, ʻoi aku hoʻi i nā hana ma hope, no ka mea he kiko maoli kona hōʻike. Eia nō naʻe, aia kekahi māhele o nā maʻi, nā hōʻailona like ʻokoʻa me nā hōʻailona o ka acromegaly. No ka hana ʻana i ka hopena maʻi a hōʻoia i ka (a haʻalele paha) ka hele ʻana o ka acromegaly, ua kuhikuhi ʻia ke kūkākūkā hopena endocrinologist, me ka ʻike ʻana, ʻenehana, a me nā hana kōkua no ka hoʻokō acromegaly.

ʻO ka ʻike loiloi o ka mea maʻi

Ma mua o ka kuhikuhi ʻana i nā kaʻina loea e pono ai a me ka mālama kūpono, hōʻiliʻili ke kauka i kahi anamnesis, hoʻoholo i ka predisposition me ka nui i ka hoʻomohala ʻia o kēia maʻi, a hana pū nō hoʻi i kahi loiloi kūpono - palpation, percussion, auscultation. Wahi a nā hualoaʻa o ka hoʻokolokolo mua, ua kuhikuhi ʻia nā kaʻina hana diagnostic e pono ai.

Nā ʻōnaehana diagnostic Laboratory

No ka hōʻikeʻana o ka acromegaly, hoʻohana ʻia nā hoʻokolohua lāʻau kūlau: nā hoʻāʻo a me ka hoʻāʻo ʻia ka urine. Eia naʻe, ʻo ka mea iʻike nui ʻia a no laila e hoʻohana pinepine ʻia iā lākou e like me ka hoʻākāka ʻana o nā hormones i loko o ke koko me ka acromegaly: STH - kahi ulu ulu a somatotropic, a me nā ulu ulu like-insulin - IGF-1.

Ke koho nei i ke pae o STH

ʻO ka hōʻoia ʻana i ka hoʻomohala ʻana o ka gigantism a i ʻole acromegaly ka hoʻonui ʻia ʻana o ka somatotropin i loko o ke koko - ka ulu ulu ʻana o ka ulu, kū ʻia e ka anion pituitary gland. He ʻano ʻokoʻa kūikawā o ka hana ʻana o STH ʻo ia ka ʻano cyclical, no laila, e hana i kahi hoʻokolohua e hoʻoholo ai i kona pae, ʻike ʻia ka nui o ke koko.

ma ka hihia mua, hana ʻia kahi ʻekolu o nā manawa he mau minamina me he 20 mau minuke., ma hope iho ua hui ʻia ka serum a ua hoʻoholo ʻia ke kiʻekiʻe o STH.

ma ka lua o kēia, hoʻokele ʻia kahi ʻelima mau peleka koko me ka manawa o 2.5 mau hola, akā e hoʻoholo ʻia ka pae ma hope o kēlā me kēia helu o ke koko. Loaʻa ka hōʻailona kuhikuhi i ka ʻike ʻana i nā waiwai āpau.

ʻO ka hōʻoia i ka pane ʻana o ka acromegaly hiki ke kūpaʻa inā ka nui o ka hormone ma mua o 10 ng / ml. Hiki ke hoʻokaʻawale ʻia ka maʻi inā ʻaʻole ʻoi aku ka nui o nā kumukūʻai ma mua o 2,5 ng / ml.

Ka manaʻo o ka pae o ka IGF-1

ʻO kekahi hōʻike ʻano screening hou ʻike ʻia ʻo ka hoʻoholo ʻana o ka pae o ka hormone IGF-1. He mānoʻi kona kiʻekiʻe a me ka kikoʻī, no ka mea, ʻaʻole ia e hilinaʻi i nā ʻano lahilahi diurnal, e like me ka ulu ʻana o ka hormone ulu. Inā ʻoi aku ka kiʻekiʻe o ka IGF-1 i ke koko ma mua o ka maʻamau, hiki i ke kauka ke kuhikuhi i ka acromegaly. Eia nō naʻe, pono e mālama ʻia kēia hoʻokolohua e hui pū me nā haʻawina ʻē aʻe, no ka mea he ʻano like o ka waiwai o ka IGF-1 ma lalo o ke ʻano o kekahi mau kumu.

e hōʻemi ʻia i ka hihia o ka hana nānā aho, hypothyroidism, ʻoi aku ka nui o ka estrogen, ka pōloli,

ke hoʻonui ʻia e like me ka hopena o ka hoʻololi ʻana i ke ʻano o ka hormone, me ka piʻi ʻana o ka nui o nā kiʻekiʻe o ka insulin i ke koko.

Hoʻololi hoʻokolohua Glucose

I ka hihia o nā kānalua kānalua, hōʻike ʻia kahi hōʻike no ka hoʻoholo ʻana i ka STH e hoʻohana ana i ka glucose i mea e hoʻomaʻamaʻa ʻia ai ka hopena o ka maʻi. No kāna hana, ke ana ka lula o ka hormone ulu o ka ulu ʻana, ma hope o ke kāhea ʻia ʻana o ka mea maʻi e lawe i kahi hopena glucose. Ma ka haʻalele ʻana o ka acromegaly, hōʻike ka hōʻike hōʻike glucose i ka hōʻemi i ka mea huna o ka STH, a me ka hoʻomohala ʻana o ka maʻi, ʻo ia hoʻi, e hoʻonui ʻia ai.

CT a i ʻole MRI

ʻO ke kumu nui a koʻikoʻi ka ʻike diagnostic ʻo CT a i MRI, e hiki ai iā ʻoe ke hoʻomaopopo i ka adenoma pituitary, me ke ʻano o ka hoʻolaha ʻana i nā kino kūloko a me nā ʻili. Ke hoʻokō ʻia nei ke kaʻina hana me ka ʻaihue kūʻokoʻa e hōʻuluʻulu i nā kiko hoʻololi, e hoʻomaʻamaʻa ana i ke kaʻina hana noiʻi a hiki iā ʻoe ke hoʻoholo i nā loli ʻano o ka pituitary a i ʻole hypothalamus.

Ma ka hana o ke kaʻina hana o nā maʻi maʻi, manaʻo nui nā mea maʻi i ka nui o ka MRI e hana ai me ka acromegaly. Hana ʻia kēia ʻano hana i ke ʻano o ka hypertrophy o nā ʻāpana o ke kino, ka ulu ʻia ʻana o nā maʻi lapaʻau, a ma hope, i ka ʻōpū o ka maʻi, i ka wā e hoʻopiʻi ai ka mea maʻi i nā māhuahua, nā poʻo, nā ʻōpū a me nā ʻōpū, a me nā hōʻailona like ʻole.

X-ray o ke kaʻe

Hoʻopili ʻia kēia kaʻina hana i mea e maopopo ai ka hoʻohālikelike ʻana i nā radiological e pili ana i ka acromegaly, a me nā hōʻailona o ka hoʻomohala ʻana o ka adenoma pituitary:

hoonui ae i ka nui o ke kanikani Turkish,

hoonui i ka pneumatization o nā sinus,

Ma ke kaʻina o ka radiography i nā hoʻomaka mua o ka maʻi, hiki ʻole i kēia mau hōʻailona ke hala, no laila, ʻoi aku, ʻoi kekahi mau mea kōkua pinepine, hōʻike ʻia nā ʻano diagnostic:

radiology o nā wāwae, kahi e ʻae ai iā ʻoe e hoʻoholo i ka mānoanoa o nā ʻīpī palupalu ma kēia wahi,

hulina e ka ophthalmologist e ʻike i ka edema, stasis a me optic atrophy, e alakaʻi pinepine ana i ka makapō.

Inā pono, ua kuhikuhi ʻia ka mea maʻi i kahi hoʻokolohua e ʻike ai i nā hoʻopiʻi: diabetes, polyposis intestinal, nodular goiter, adrenal hyperplasia, etc.

Wahi a Acromegaly i nā maʻi i hiki ʻole ke hoʻopiʻi ʻia kona mālama ʻana a hiki i hope. ʻO ka hana nui o ka ulu ulu ʻana ke alakaʻi i ka maʻi kīnā a e hōʻemi i ka manawa o ke ola lōʻihi. Inā loaʻa iā ʻoe nā hōʻailona mua, pono ʻoe e nīnau i ke kauka. Hoʻokahi wale ke kauka ma hope o ka lawe ʻana i nā hoʻokolohua āpau i hiki ke hoʻāʻo i ka maʻi a kuhikuhi i ka hana kūpono.

Nā Kuhi a me nā Methods

ʻO nā pahuhopu nui o ka mālama acromegaly:

kaemi ʻana i ka huni o ka ulu ʻana o ka hormone (ulu i ka hormone ulu),

ka hoʻololi ʻana i ka hana o ka insulin-like growth factor IGF-1,

ka hōʻemi ʻana o ka adenoma pituitary,

Hoʻopau ʻia ka mālamaʻana i kēia mau ʻano:

Ma hope o nā haʻawina loea, koho ke kauka i ke ala kūpono loa, i ke ʻano o ka papa o nā maʻi a me nā ʻano pilikino o ka mea maʻi. ʻO ka manawa pinepine, ʻo ka acromegaly, ke mālama nei i kahi mea e pono ai ka hoʻokō ʻana, e lawe ʻia ana i nā ʻano like ʻole.

Hoike ʻike

Nā mea lawelawe

ʻO ka ʻoihana maikaʻi loa no ka acromegaly i manaʻo ʻia he hana ia e hoʻopau i ka adenoma pituitary. Hoʻomaopopo nā kauka i nā mea maʻi no ka microadenoma a me ka macroadenoma. Inā ʻike ʻia ka ulu wikiwiki ʻana, ʻo ka hana nui wale nō ka manawa e hoʻōla ai.

Hana ʻia ka hoʻomaʻamaʻa ma kekahi o ʻelua ala:

Ke kaʻina hōʻeuʻeu minimally. Hoʻokuʻu koke ʻia ka ʻaole me ka hana ʻole ʻana ma ke poʻo a me ka craniotomy. Hoʻopili ʻia nā hana maʻi āpau ma o ka wehe ʻana o ka ihu me ka hoʻohana ʻana i nā mea hoʻohana endoscopic.

ʻO ke ʻano transcranial. Hoʻohana wale ʻia kēia ala o ka hana inā ua hiki ke hōʻea ke nānā i kahi nui nui a hemo ʻole i ka adenoma ma o ka ihu. ʻO ka ʻoihana a me ka wā hōʻola ke paʻakikī, no ka mea, ʻo ka craniotomy ke hana nei.

I kekahi manawa ua hoʻi mai ka acromegaly ma hope o ka hoʻomaʻemaʻe. ʻO ka liʻiliʻi o ke kaila, ʻoi aku ka nui o ka manawa e kala ʻia. No ka hōʻemi i nā pilikia, pono ia e hoʻokō i ka nānā ʻana i nā lāʻau lapaʻau i ka manawa kūpono.

ʻO ka lāʻau lapaʻau

Kauka nā kauka i nā lāʻau lapaʻau no ka mālama paʻakikī o nā maʻi.Ma ke ʻano o monotherapy, ua hōʻike pinepine ʻia nā lāʻau lapaʻau, ʻoiai lākou e kōkua i ka hōʻemi ʻana i ka ulu ʻana o ka ulu ulu ʻana, akā ʻaʻole hiki iā lākou ke hōʻola nui i ka maʻi.

I ka manawa pinepine, ua kuhikuhi ʻia nā lāʻau lapaʻau i loko o ia mau hihia:

ina ʻaʻole i hoʻohua ʻia nā hopena,

inā hōʻole ka mea maʻi i ka hāʻawi ʻana i nā maʻi maʻi.

inā aia nā contraindications no ka hana.

ʻO ka lawe ʻana i nā lāʻau lapaʻau e kōkua i ka hōʻemi ʻana i ka nui o ka nui, no laila ke kau ʻia ka lāʻau lapaʻau ma mua o ka hoʻomaʻemaʻe.

No ka mālamaʻana i ka acromegaly, hoʻohana ʻia nā lāʻau o nā pūʻulu:

kahi kikoʻiwahiwa (somatostatin, lantreoditis),

ka ulu ʻana i ka mea maʻi receptor blockers (pegvisomant).

ʻO ka ʻae ʻia nā lāʻau lapaʻau e lawe ʻia ana e like me ke kuhikuhi ʻana e kahi kauka. ʻO ka lāʻau lapaʻau pilikino, me kahi hōʻola o ka iwi hiki ke hoʻonāukiuki i ka papa o nā maʻi.

Hāʻawi i ka maʻi radiology

Hoʻohana pinepine ʻia ka lāʻau radiadi i ka mālama ʻana o ka acromegaly, no ka mea ke loaʻa pinepine ka hoʻopiʻi - ka hoʻomohala ʻana i ka hypopituitarism. E hoʻomaka paha nā ʻōkohu i kekahi mau makahiki ma hope o ka mālama ʻana. ʻO kahiʻoi aku, ʻo ka hopena i ka hapanui o ka hoʻohana ʻana i kēia ʻano hiki ʻole koke.

ʻO kēia mau kaʻina hana o ka radiation radiation i kēia manawa:

Ke hoʻohana pono nei ka hoʻohana ʻana i ka maʻi radiation me nā lāʻau lapaʻau.

ʻO ka hua'ōlelo acromegaly maʻi ka mea he maʻi ia e hele ana i loko o kahi kanaka nāna i loaʻa kahi ulu o ka nui o ka ulu ʻana o ka hormone, ʻo ia hoʻi, nā hōʻike hōʻike ʻana i ka hana hoʻoulu i ka hormone ulu ma hope o kahi wā o ka make. Ma muli o kēia, ke hoʻohālikelike ʻia o ka ulu ʻana o ke kōpaʻa holoʻokoʻa, hōʻino nā ʻāpana kūwili a me nā ʻāpana palolo o ke kino (ʻo ia ka mea i hoʻomau ʻia o ka nitrogen i loko o ke kino). Hoʻākāka nui ʻia ʻo Acromegaly ma nā wāwae o ke kino, ke alo a me ke poʻo holoʻokoʻa.

Hoʻopilikia ʻia kēia maʻi i nā wahine a me nā kāne ma hope o ka pau ʻana o ka wā ulu. ʻO ka maʻi ākea o ka maʻi mai ka 45-70 kānaka ma kahi miliona miliona mau kānaka. Loaʻa pinepine ʻia ke kino o kahi keiki i kēia maʻi. I nā hihia pinepine, i ka ulu ʻana o nā keiki, ʻo kēia nui o ka ulu ʻana o ka hormone ulu e alakaʻi i kahi kūlana i kapa ʻia ʻo gigantism. Kēia hoʻololi e like me ka hiʻona no ka nui o ke kaupaona ʻana a me ka ulu iwi.

No ka mea maʻamau ka acromegaly, a hele mālie ka maʻi maʻi, ʻaʻole maʻalahi ke hoʻomaopopo i kēia maʻi i nā wā mua.

Hoʻokomo wale kēia mau mea ʻaʻole wale no ka mea hoʻonāukiuki i ka hormone ulu, akā ke hoʻololi nei i nā hana ola olakino ʻē aʻe:

Kūpono ʻana o ka cortex adrenal.

Ma muli o acromegaly, hoʻopilikia ka metabolism, i ka hapanui e alakaʻi i ka maʻi mellitus me ka lawe aku i kahi pilikia nui o ke ola o ke kanaka. Akā mai huhū, aia kekahi mau hoʻomaʻamaʻa lāʻau lapaʻau i hiki ke hōʻoluʻolu nui i nā hōʻailona a hōʻemi i ka hoʻonui hou ʻana o ka acromegaly.

ʻO nā hōʻailona o ka acromegaly kahi hōʻike hōʻike lohi a hoʻomohala o ka hoʻomohala ʻana i ka maʻi. Hōʻea kēia maʻi ma muli o ka nānāʻole o ka hormonal e ka hoʻololi ʻana i ka helehelena, a me ka hōʻemi ʻana i ka pono o ka pono. Aia nā poʻe maʻi i hōʻike i kēia maʻi ma hope o 10 mau makahiki. ʻO nā hoʻopiʻi nui o nā maʻi he hoʻonui i nā auricles, ihu, nā wāwae o nā lima a me nā wāwae.

I ka hoʻomohala ʻana i kahi hakakā maikaʻi i ka maʻi, ʻelua mau hopena koʻikoʻi: nā neoplasms malignant a me nā patology o ke ʻano o ka pūnaehana cardiovascular. ʻEhā he ʻano nui e hoʻopaʻa ʻia ai kēia maʻi:

Ka hana maʻi. Hoʻopauʻokoʻa loa nā kauka kūpono i nā ʻōpū. Hiki i kēia ala ke kiʻi wikiwiki i ka hopena. Aia kekahi mau ʻōkuhi ma hope o ka hoʻomaʻamaʻa ʻana.

Radiation therapy a i ʻole radiation. ʻO ka hapa pinepine, ua hoʻohana ʻia kēia ʻano hana i ka hihia inā ʻaʻole ke kōkua o ka pale ʻana. Eia kekahi, ʻo ka irradiation kekahi i kekahi mau ʻōwili o ka noiʻi: ua kau ʻia ka nerve optic, kahi paʻa o ka lolo.

ʻO ke ʻano lāʻau lapaʻau. Hoʻoholo ʻia ʻo Acromegaly me kēia mau ʻanoʻano like ʻekolu:

Nā hōʻailona o ka FTA (lōʻihi (Samatulin a Sandostatin LAR) a me ka hana pōkole - Sandostatin Octroedit).

ʻO nā agonist Dopamine (ergoline a me nā mea kanu nonergoline).

Ua hui ʻia. Mahalo i kēia ʻano, ua hoʻokō ʻia ka hopena hopena maikaʻi loa.

Akā ke hōʻike nei i kahiʻike ke mālama nei nā kauka i nā lāʻau lapaʻau. Ua loaʻa kēia hopena i ka hopena maikaʻiʻole i ke kino o ke kanaka.

ʻO kahi papa o nā lāʻau lapaʻau e pale aku i nā hopena o ka acromegaly e lawa:

He hoʻoponopono home no Genfastat.

ʻOcride kahi aʻa mololytic.

Sandotatin - Beta - ka mea hao kiʻi a Adrenergic.

ʻO Samatulin kahi antiseptic.

I ka hapa nui o kēia mau lāʻau lapaʻau, ʻo ka waiwai ikaika he octreodite. Pau nā dosages a me nā regimens lapaʻau i kuhikuhi wale ʻia e ke kauka hele mai.

ʻO ka mea e pono e hoʻomanaʻo ʻia i ka wā e hoʻohana ana i nā lāʻau lapaʻau i ka lahui i ka mālamaʻana i ka acromegaly

Hoʻohana e hoʻoikaika i ke kino a hoʻomaikaʻi i ke kaʻina hoʻōla i nā decoction a me kaʻaila i hoʻomākaukau ʻia mai nā mea kanu a me nā mea kanu e like me:

licorice a me ke ginseng kumu

ʻO Acromegaly, ʻoluʻolu o ka poʻe no ka mālama ʻana i hoʻohana ʻia ma hope o ke kuʻikahi me ke kauka, hiki ke kōkua ʻia e hōʻoluʻolu. Pono e hoʻomanaʻo ʻia ʻo ka infusions a me ka teas mai nā lāʻau kanu mea pono e mālama ʻia i kahi lōʻihi. Pono lākou e hoʻohana i loko o nā hola 24 ma hope o ka infusion a me ke kaula.

ʻO kēia no ka mea inā ke kū lōʻihi lākou, e nalowale ana lākou i nā mea ho'ōla a pau, hoʻihoʻi hou ʻia a hōʻino hou ʻia, hiki iā lākou ke hōʻeha nui. I ka mālama ʻana o ka acromegaly me nā ʻoni like ʻana, ʻaʻole kūpono kēia, no ka mea, e hoʻopilikia ʻia kekahi hopena maikaʻi ʻole i ke kino a me ka hana o ka kipi thyroid, ka mea i hāʻawi ʻia i kekahi o nā kuleana nui i kēia hihia.

ʻO kahi hana kauoha, pono e hoʻonohonoho pū me kahi loea, ʻo ia ka mālama mālama i ka meaʻai. Hiki iā ia ke hoʻoikaika i ke kino, e hoʻolōʻihi i ka metabolism a hoʻonui i ke kiʻekiʻe o ka pale ʻana o ke kino.

ʻO nā hiʻohiʻona noi loa

Inā loaʻa iā acromegaly, kōkua nā kuʻuna pilikino e kāpae i kekahi mau hōʻailona o ka maʻi. ʻO kekahi o nā loea kaulana loa he ʻano kāwili e hui ʻia ana o nā hua pākupu, mauʻu primrose, ʻōpala aʻa ʻehā o ka ʻōmole, nā hua sesame a me 1 tsp. meli. Pono e hoʻopili ʻia ka mea i hāʻawi ʻia no 1 tsp. ʻehā lā i ka lā. Inā ma hope o nā lā 14-16 ʻaʻohe loli maikaʻi i ke kaʻina mālama, pono, ma hope o ke kūkā ʻana me ka endocrinologist, e hoʻoponopono i ka ʻano hana a hōʻole ʻole e hoʻohana i kēia lāʻau.

Hoʻoulu me ka hoʻōla lāʻau acromegaly e pili ana i ka hoʻohana ʻana i nā uku o nā mea kanu. ʻO nā mea lapaʻau hōʻike i hōʻike ʻia me nā ʻano mea e like me:

Hoʻohui i nā mea kanu (ma kahi o 10 g.) Kaʻa ʻia i 200 ml. wai wai. No ka hoʻohana ʻana i ka hopena i hōʻike ʻia e pono ai no 40-50 ml. ma mua o ka ʻai ʻana a me kēia hana e hana ma ka liʻiliʻi he 4 i loko o 24 mau hola.

Pono e hoʻomaopopo pono i ka hoʻohana pono ʻana i nā kūlohelohe o ka lāhui a me nā kūlohelohe i ka mālama ʻana o ka acromegaly. ʻO kēia ma muli o ka hopena maikaʻi ma ka kelele endocrine. Eia nō naʻe, ʻo ka mea nui o ka mālama ʻana i ka acromegaly e hana ʻia ʻaʻole ma ka pres presaries wale nō, akā i ka hoʻohana ʻana i nā lāʻau lapaʻau, nā hana o ka hōʻola o ka hoʻihoʻi. Me ka hui pono o nā ala hōʻike, hōʻike ʻia ka hopena ma 100%.

He aha ka acromegaly?

No ka hana ʻana i ka ulu ʻana o ka ulu ulu, ʻo ka māhele o ka lolo - ka lānipili pituitary - ke kuleana. ʻO ka maʻamau, hana ʻia kēia hāmeʻa i nā keiki mai ka lā mua o ke ola, ua hoʻoikaika maoli ia i ka wā o ka wā ʻōpiopio, i ka manawa e piʻi ai ka ulu o ka ulu a hiki i 10 cm i kekahi mau mahina. Ma hope o kēia hana e pau ai, hoʻemi ʻia ka somatotropin i kāna hana i kēia kuhikuhi: e ulu ana nā mea kanu ma ka awelika o 15-17 mau makahiki no ka wahine a me 20-22 no nā kāne.

Acromegaly - He kūlana kēia no kahi holina o ka ulu ʻana o ka ulu a hoʻoulu i nā pākeke. Aia nā hihia i ka hoʻomaka ʻana e hana hou i nā maʻi maʻi i hana maoli ʻia ma mua.

ʻAʻole kū i ka hormone ulu ke hana i ka neʻe pituitary aniani ma nā pākeke.

Mālama kēia hānai a me ke maʻamau, kuleana no:

kalapuhia ka hana momona - pale i ka pancreas, nānā i ke kō koko,
momona metabolism - i hui pū me nā sex sex e hoʻoponopono i ka hoʻolaha ʻana o ka momona subcutaneous,
ka paʻakai-paʻakai wai - hoʻopilikia i ka hana o nā keiki, diuresis.

"Ka hana" a ka "pituitary gland" a me kekahi ʻāpana o ka lolo. hypothalamus. ^ E Ha yM. ʻO ka mea hope loa no ka hona o ka somatoliberin, e paipai i ka hoʻohui ʻana o ka hana somatotropic a me somatostatin - kēlā, kēia pāpā 'ana a me ka' ae 'ole i ka hopena e pili ana i nā kino kanaka.

Hiki i kēia kaulike ke kūlike i ka lāhui, nā ʻano genetic, ka wahine, ka makahiki, a me nā ʻano kīnā. No laila, ma ka maʻamau, ʻoi aku ke kiʻekiʻe o nā maka o ka lāhui Europa, ma mua o nā ʻelele o ko ʻAsia kanaka, ʻoi aku ka lōʻihi o nā kāne a me nā wāwae ma mua o nā wahine, etc. Ua noʻonoʻo ʻia kēia mau mea he ʻano ʻē o ke ʻano.

Ke kamaʻilio nei e pili ana i ka acromegaly, ke kuhi nei i kahi maʻi pathological o nā hana o ka hypothalamus a me nā pituitary gland. Nui nā kumu, akā hiki ke loaʻa i ka maʻi ʻokoʻa i nā hopena o nā loiloi, ʻo ia ka pae a me ka manawa o ka hūnā ʻana o ka hormone ulu a me IRF I, he mea ulu ulu like-insulin.

ʻO Acromegaly kahi maʻi o nā pākeke, ma mua o ke olakino ʻia. Inā hoʻonuiʻia nā hōʻailona mai ka wā kamaliʻi, a laila i kapa ʻia nā kūlana hono ʻaʻa.

ʻO nā ala lua ʻelua ʻaʻole ia e hoʻopilikia nui wale i ke ʻano o kahi kanaka. ʻO lākou kumu he helu nuiI waena o ia mau hana hoʻonā, kahi predisposition i ka hoʻomohala ʻana o ka maʻi maʻi o kekahi ʻano, a me nā hopena koʻikoʻi ʻē aʻe.

Hōʻike ka wā kūpono a me nā hana lapaʻau e mālama i ka maʻi, pale i nā hopena lōʻihi loa no ke olakino a me ke ola. Pono ka hopu ʻia o nā meʻeha i ka hoʻomaka mua ʻana o nā maʻi endocrine, i kekahi mau hihia, ma muli o nā kumu, hiki ke hoʻopau piha i nā hōʻailona.

Nā kumu o Acromegaly

ʻO ka hana maʻamau no ka hoʻomohala ʻana i nā hōʻailona o ka acromegaly ʻoiai ke neʻe pololei ʻana o nā ulu ulu, e hoʻonāukiuki i ka hoʻomaʻamaʻa pathological o nā huina.

I waena o nā kumu koke.

ʻO nā ʻōpū o Benign, ma ke ʻano he kānāwai, ua lilo ka adenomas hipoteary i ke kumu kūpono o ka acromegaly i nā mea he 90% o nā hihia. Ua pili pū ʻia ka gigantism keiki me ke ʻano like like ʻole, no ka mea ke ulu pinepine nei nā neoplasms i kahi keiki i ke keiki ʻōpio a i ʻole ke ʻano ʻōpiopio me ka hoʻomaka ʻana o ka pupule.
ʻO nā maʻi a me nā ala ʻē aʻe o ka hypothalamus, kahi e hoʻoiho ai i kahi hemahema o kahi hormone e pale ana i ka mea huna o ka ulu ulu ʻana, a i ʻole, e hoʻolilo i ka lime pituitary e hana nui ai i ka nui o ka waiwai. ʻO kēia ka lua o nā kumu maʻamau maʻamau o ka acromegaly.
ʻO ke kumu koke o ka hoʻomaka ʻia ʻana o ka maʻi nui loa ke hōʻeha loa i ka ʻōpala, ka lolo, me ka concussion. Hoʻoneʻe a hōʻeha paha i kahi meaʻino, hopena i nā cysts a i ʻole nā palū. He mōʻaukala o nā hapanui maʻi nā maʻi e loaʻa ana i ka acromegaly, ka hōʻeha o ke poʻo a me ka hōʻeha koʻikoʻi.
Hoʻohui ka hana ʻana o ka IGF, e pili pū me nā ʻōpū, nā ʻōkuhi o ka ʻōnaehana hormonal, ate. ʻO ka protein iho i hoʻāla ʻia e nā hepatocytes, akā hiki i nā mea i loko o ke koko ke hoʻōla ʻia e nā kumu he nui - i ka insulin, ke ʻano o ka testosterone a me ka estrogen, a me ka hana o nā kipi thyroid.
I nā hanana pinepine, loaʻa kekahi kahi o ka sekene ectopic o ka ulu lāʻau e nā maʻi ʻē aʻe - ʻo ka thyroid, ovaries, testicles. ʻAʻole kēia kahi kulekele maʻamau maʻamau, akā loaʻa nō hoʻi i nā mea maʻi me ka acromegaly a me nā gigantism.

Hiki iā ʻoe ke hoʻomaopopo i ka maʻi ma kahi awiwii ka wā he hoʻomaka nā hoʻololi liʻiliʻi. I kekahi pākeke, loli koke ka helehelena, kūkulu i kahi kiʻi lāʻau lapaʻau o kāna maʻi. Ma ka hihia o kahi keiki me ka gigantism koʻikoʻi, nānā kahi māka piha o ke keiki e ka endocrinologist, neuropathologist a me nā mea loea e pono ai.

Ka Hoʻōla ʻAcromegaly

E like me nā maʻi endocrine āpau, mālama maikaʻi ʻia ka acromegaly. ^ E Ha yM. No laila, he mea nui ka ʻike mua ʻana a me ka nānāʻana i nā kaʻina hana, ka mea e ʻae ai i ka nānā aku i ka manawa o ka pathology a pale i ka wā e loaʻa ai nā hōʻeha koʻikoʻi. I kēia manawa, kahi hōʻola holoʻokoʻa me ka mea maʻi e hoʻi hou ana i ka'āina ma mua o ka maʻi ua ʻike ʻia he ʻokoʻa, akā, hiki ke lawe ʻia nā hana e pale ai i ka holomua o ka maʻi.

Hoʻololi ka hana kūpono:

Hoʻolā hewa - ka lawe ʻana o nā adenomas pituitary, nā ʻōpū o ka hypothalamus a me nā mea ʻē aʻe neoplasms i loko o ka lolo e hoʻopilikia ai i ka hana o ka ulu ulu ʻana. ʻO ka mea pōʻino, ʻaʻole kūpono ʻole kēia ala, ʻo ka manawa i ka nui o ka maʻi i liʻiliʻi iki, akā hoʻomau ia e pili i ke ʻano o ka palupalu o ka lolo.
Hāʻawi i ka maʻi radiology - hele mai e hoʻololi i ka hana, inā ʻaʻohe ala e hoʻihoʻi pololei i ka ʻōpū. Ma lalo o ka mana o ka radiation kūikawā, hiki ke hoʻokō kūpono i ka neʻe ʻana o nā neoplasm, kona hōʻemi. Cons of lapaʻau: paʻakikī e ʻae i ka mea maʻi, ʻaʻole mau i ka hopena i makemake ʻia.
Hōʻikeʻike Hoʻopau nā mea huna STH, kekahi o nā lāʻau lapaʻau kūikawā ʻo Sandostatin. ʻO ka koho o ka lāʻau e pono e hoʻokau ʻia e ka endocrinologist, a me ke ʻano, ka hoʻoponopono regimen.
ʻO kahi ʻāpana koʻikoʻi i ke kākoʻo ʻana i nā mea maʻi me ka acromegaly holomua ke ʻaukā, nā chondroprotectors a me nā mea āpau e kōkua i ka hōʻemi ʻana i nā hōʻike o ka maʻi.

Me ka hoʻomaka ʻana o ka maʻi a me ka haʻalele ʻana o nā hoʻopiʻi koʻikoʻi, hiki ke loaʻa i nā hopena maikaʻi, a hoʻi i ka hoʻi ʻana o ka mea maʻi i ke ola maʻamau. Eia kekahi, ua kau ʻia nā mea maʻi ma ka mellitus prophylaxis, Kauhi ʻia meaʻai kalaiwa kiʻekiʻe, he mea kōkua e hoʻolako i ke kino i ka nui o nā pono o ke kō, akā ke emi nei ka nui o ka glucose a me ke kō, no ka mea, ua hoʻomau ke ahonui o ke kino i kēia mea.

Nā kumu kumu o ka maʻi

ʻO ka pono nui no ka hoʻomohala ʻana i ka acromegaly kahi hoʻopiʻi kūlohelohe o ka pituitary gland, kahi i hōʻike ʻia i ka meʻe nui o somatropin (ulu i ka hormone). I ka wā ʻōpiopio, ua hoʻonani ka haehae i ka ulu ʻana o ke aʻe o ke keiki, a i nā pākeke ke hoʻoponopono i ka momona o ka momona a me ka momona o ka momona. Me ka acromegaly, nā seluitary no nā kumu like ʻole e kūleʻa ʻole me ka ʻole e pane aku i nā hōʻailona kino (ʻo kēia ka mea i loaʻa i ka hapa nui o nā maʻi maʻi).
ʻO nā kumu nui o ka hoʻomohala ʻana o ka maʻi ma waena:

ʻO ka adenoma pituitary, ka mea e hoʻonāukiuki i ka hiʻona o ka wahine somatropin.

Nā hoʻololi i loko o ke alo o ka limu mua o ka hypothalamus.
Hoʻonui ka mahele o nā ʻili o ke kino i ka ulu ulu ʻana.
Heredity, ka hele ana o kahi maʻi o ka samatotrophinomas.
ʻO ke ʻano o nā cyst i ka lolo, ka hoʻomohala ʻia e hiki ai ke hōʻeha ʻia e kekahi ʻeha hōʻeha o ka traumatic a he maʻi hōʻeha paha.
ʻO ka heleʻana o nā pehu i loko o ke kino.

Nā kahua o ka hoʻolālā Acromegaly

Hele ka maʻi i ʻekolu mau degere o ka hoʻomohala ʻana i ka maʻi:

ʻO ke ʻano mua he preacromegalic. Ma kēia ʻano, ʻaʻohe hōʻailona o ka maʻi, no laila aneane hiki ke hoʻomaopopo a hiki ke ʻike wale ʻia ma ka manawa kūpono a ma ke ʻano he loiloi laulā.
Hōʻike ʻia ka pae hypertrophic e nā hōʻike mua o nā hōʻailona, nā loli o waho ma nā ʻaoʻao kino. Ma kēia ʻanuʻu, ulu ka ʻōpala i nā nui a me nā hōʻailona ākea: hoʻonui nui i ke alo o ka intracranial, ke oki ʻana i ka hihio, nā nāwaliwali ākea o ke kino.
ʻO ka pae cachectal ka hope hope loa o ka maʻi, i ka mea e nānā ai ke kahaha o ke kino, nā ʻano ʻano hoʻopiʻi like ʻole.

ʻO ka pale ʻana i ka maʻi

I mea e pale ai i ka hoʻomohala ʻana o ka acromegaly pituitary, pono e hahai i nā keʻakeʻa pale maʻalahi:

Hōʻalo iā craniocerebral a i ʻole nā hōʻeha poʻo.
Pale i ka hoʻomohala ʻana o nā maʻi ʻo ka pale o ka lolo (no ka laʻana, meningitis).
Hana i nā hoʻokolohua maʻamau no ka ulu ʻana o ka hormone i ke koko.
E mālama pono i ke olakino o ka ʻōhumu a hoʻokō i kā lākou manawa hoʻoponopono.

Acromegaly - nā kiʻi, nā kumu, nā hōʻailona mua, nā hōʻailona a me ka mālama ʻana i ka maʻi

ʻO Acromegaly kahi ala pathological e holomua ma muli o ka overproduction e ka lula pituitary o somatotropin ma hope o ka ossification o ka cartilage epiphyseal. ʻO ka pinepine, ua hūnā ka acromegaly me ke gigantism. Akā, inā hiki mai ka gigantism mai ka wā kamaliʻi, ua pākē wale ka poʻe pākeke i ka acromegaly, a ʻike ʻia nā hōʻailona ʻike he 3-5 mau makahiki ma hope o ka hoʻomaʻamaʻa ʻana i ke kino.

He maʻi ʻo Acromegaly kahi e ulu ai ka ulu ʻana o ka ulu ulu ʻana (ʻo ka ulu ulu ʻana o nā hormone ulu), ʻoiai ke kuhi hewa ʻana o ka ulu ʻana o ka huila a me nā kino kūloko, a me ka mea hou aku, aia ka maʻi metabolic.

Hoʻokomo ana ʻo Somatropin i ke ʻano o ka hana o ka protein, ʻoiai ke hana nei i nā hana like:

e hoʻohiolo ana i ka wāwahi ʻia o nā protein,
hoʻololi i ka hoʻololi ʻana o nā momona momona,
ho'ēmi i ka waiho ʻia o nā momona momona i loko o ka kiko subutanantile,
hoʻonui i ka māhele ma waena o ka pīpī molī a me ka kiko adipose.

He mea kūpono ia e pili pono ana ka pae o ka hormone i nā kuhikuhi makahiki, no laila e mālama ʻia ana ka ʻike kiʻekiʻe loa o ka somatropin i nā makahiki mua o ke ola a hiki i ka ʻekolu makahiki, a ʻo kona hana kiʻekiʻe loa i loaʻa i ka wā ʻōpiopio. I ka pō, hoʻonui nui ka somatotropin, no laila ke hele nei ka haunaele hiamoe i ka emi.

Hōʻike ia me nā maʻi o ka ʻōnaehana o ka pōpilikia e pili ana i ka gland pituitary, a i kekahi no ke kumu ʻē aʻe, hoʻopiʻi ʻia ka maikaʻi o ke kino a me ka hormone somatotropic. I ka hōʻike kumu, ua hoʻonui nui ʻia. Inā i pili kēia i ka wā ʻelemakule, ʻoiai ua paʻa nā mea kanu ikaika, hoʻoweliweli kēia me ka acromegaly.

I ka 95% o nā hihia, ʻo ke kumu o ka acromegaly he pūpeti hepeti - he adenoma, a i ʻole somatotropinoma, e hāʻawi ana i ka nui o ka huna ʻana o ka ulu lāʻau, a me kona komo ʻole ʻana i ke koko.

E like me ke kānāwai, ulu ka acromegaly ma hope o nā hōʻeha o ka pūnao o ka pūnao o nā kikowaena, nā maʻi maʻi infectous a i ʻole-infectious. Hoʻokahi kekahi kuleana i ka hoʻolālā ʻana i ka hoʻoilina.

Hoʻoikaika pinepine ʻo Acromegaly, no laila ke hele pinepine ʻia nei nā mau kumu mua. Eia kekahi, paʻakikī loa kēia hiʻohiʻona no ka hoʻomaka mua o ka maʻi Patology.

Hōʻike ke kiʻi i kahi hōʻailona o ka acromegaly ma ka maka

Hoʻomaopopo nā poʻe hōʻike i nā kumu nui o ka acromegaly pituitary:

headache maʻamau, maʻamau no ka hoʻonui i ka hoʻoikaika intacranial,
hoʻomoe ʻia ka hiamoe, luhi, luhi
photophobia, lohe pio,
mahuahua manawa,
ka ʻōpū ʻana o nā ʻōpū kuʻuna a me ke alo,
luhi, hoʻemi ʻia ka hana
ʻeha i ke kua, ko nā ʻuʻuku, ka palena o ka hooweliweli ʻana, ʻo ka ʻeha o nā lōpū,
kaohuu

ʻO ka hoʻonui nui aʻe o ka ulu ʻana o ka hormone ulu e alakaʻi i kahi loli kino ʻano loli i nā maʻi me ka acromegaly:

Ka pīhoihoi o ka alelo, nā ʻōnaehana salivary a me ka larynx e alakaʻi i kahi kaohi o ka leo o ka leo - lilo ia i kuli, ʻike pū ʻia.
hoʻonuiia iwi zygomatic
ʻāʻī haʻahaʻa
nā maka ʻōpū
hypertrophy o nā pepeiao
ihu
lehelehe.

Ke hana nei i nā hiʻohiʻona facial rougher.

Hoʻololi ka uluna ʻana, aia ka hoʻonui i ka umauma, kahi hoʻonui o nā kikowaena intercostal, kūlou ka kuʻi. Ke ulu nei ka ulu ʻana o ka cartilage a me ka hoʻopili hoʻohui ʻia i ka palena o ka holo ʻana o nā ʻōpū, ko lākou hoʻohālikelike, ʻike ʻia ka ʻōpū.

Ma muli o ka hoʻonui o nā kino i loko i ka nui a me ka nui, e hoʻonui ana ka ʻōpū o ka puʻuwai o ka mea maʻi, ka mea e alakaʻi ai i ka nānā ʻana o nā nāwaliwali, nā luhi, a me ka hoʻohaʻahaʻa wikiwiki i ka hana hana. ʻO ka hypertrophy o ka puʻuwai a me ka puʻuwai puʻe e holomua wikiwiki.

Hāʻawi ʻia ka Acromegaly e nā papa lōʻihi, pālua. Mamuli o ka paʻakikī o nā hōʻailona i ka hoʻomohalaʻana i ka acromegaly, aia kekahi mau manawa:

ʻO Preacromegaly - ke ʻano o nā hōʻailona mua, ʻike ʻia ka ʻimi pinepine loa, no ka mea, ʻaʻole i hoʻokō ʻia nā ʻōuli. Akā, i kēia hana, hiki i ka hoʻomohalaʻana i ka acromegaly me ke kōkua o ka compute tomography o ka lolo, e like me ka piʻi ʻana o ka hormone ulu o ke koko,
Hōʻike Hypertrophic - i ʻike ʻia nā hōʻailona o ka acromegaly.
Tumor: hōʻike ʻia ia e nā hōʻailona o ka hanaʻino a me ka hana lēwa ʻole o nā hale e pili kokoke ana. ʻO kēia paha ka hoʻonāukiuki i ka hana o nā lālā o ka hihiʻo a i hoʻonui nui i ka hana intracranial.
ʻO ke kahua hope loa ka maʻi o ka cachexia, ua hui pū ʻia me ka mauʻu ma muli o acromegaly.

Lawe i nā hoʻokolohua lapaʻau pono kūpono i ka manawa e kōkua ai i ka ʻike ʻana i ka maʻi ma kahi wā ʻōiwi.

ʻO ka pōʻino o ka acromegaly i kāna mau hoʻopiʻi, ka mea i ʻike ʻia mai ka aneane āpau o loko. Nā maʻi maʻamau:

nā maʻi kūwaho
ke ʻano o ka ʻoihana endocrine,
hunopihi
fibroids fibro,
polycystic ovary syndrome,
polyps pōpilikia
maʻi maʻi coronary artery
puʻuwai paʻakikī
haehae maʻi.

ʻO ke ʻano o ka ʻili, kū mai nā ʻano hana.

lālani ʻana i nā ʻili o ka ʻili,
kaʻau kaua hua ʻole
seborrhea,
ka momona loa
hydradenitis.

Inā ʻike ʻia nā hōʻailona mua e hōʻike ana i ka acromegaly, pono koke ʻoe e hoʻopili i kahi kauka kūpono no ka maʻi maʻi a me ka maʻi kūpono. Hōʻike ka Acromegaly ma ke kumu o ka ʻike hōʻike koko no ka pae o IRF-1 (somatomedin C). Ma nā helu maʻamau, ua noi ʻia kahi hōʻike hoʻonāukiuki me kahi ukana glucose. No kēia mea, ʻike ʻia ka mea maʻi me ka acromegaly hopohopo i kēlā me kēia 30 mau minuke 4 mau manawa i ka lā.

E hōʻoia i ka maʻi maʻi a huli i nā kumu:

ʻO ka nānā nui ʻana o ke koko a me ka wai.
Hōʻike koko koko biochemical.
Hōʻōkuʻuʻu o ka kelu thyroid, ovaries, uterus.
X-ray o ka ʻōpala a me nā wahi o ke kanikani Tureke (kahi kulu iwi i ka ʻōpala i kahi i loaʻa ai ka kelepona pituitary) - ke piʻi nui o ka nui o ke kanikani a i ʻole ka bypass.
ʻO ka scan o CT o ka puʻuwai pituitary a me ka lolo me kahi hoʻohālike mandatory a i ʻole MRI me ka pale ʻole
ʻO ka nānā maʻi Ophthalmological (ʻike maka) - i loko o nā mea maʻi e loaʻa ka emi ʻana i ke kōkuhi ʻike, ʻaeʻī i nā kula ʻike.
Hoʻohālikelike aʻo i nā kiʻi paʻi o ka mea maʻi i nā makahiki he 3 i hala.

I kekahi manawa ke hoʻoikaika ʻia nā kauka i nā hana lapaʻau no ka mālama ʻana i ka acromegaly. Hoʻohā pinepine ʻia kēia mea inā hōʻea nā ʻōkuhi i hoʻokumu ʻia i nā nui nui a hōʻuluʻulu i ka nui o ka lolo.

ʻO ka mālama ʻana no ka acromegaly pituitary i ka hoʻohana ʻana i nā lāʻau lapaʻau e ʻae ana i ka hana ʻana o ka ulu ulu ʻana. I kēia manawa, ua hoʻohana ʻia nā pūʻulu ʻelua o nā lāʻau i kēia.

Hoʻokahi hui - hui o somatostin (Sandotastatin, Somatulin).
ʻO ka hui ʻelua he agonists dopamine (Parloder, Abergin).

Inā loaʻa i ka adenoma ka nui o ka nui, a inā e holo holomua ka maʻi, ʻo ka lāʻau lapaʻau wale nō ʻaʻole e lawa - i kēia hihia, ke hōʻike ʻia nei ka mea maʻi. Me nā ʻōpū ākea, kahi hana ʻelua hana. Ma ka manawa like, hoʻokaʻawale wale ia ka hapa o ka hua i loko o ka cranium, a ma hope o kekahi mau mahina, lawe ʻia ke koena o ka adenoma pituitary ma o ka ihu.

ʻO kahi hōʻailona kuhikuhi no ka hana hoʻokipa wikiwiki loa o ka ʻike. Hoʻokuʻu ʻia ka nūpepa ma ka iwi sphenoid. I ka 85% o nā mea maʻi, ma hope o ka hemo ʻana o ka nalo, kahi hōʻemi nui o ka pae o ka ulu ʻana o ka hormone ulu i ʻike ʻia i ka normalization o nā hōʻailona a me ke kala paʻa mau o ka maʻi.

Hōʻike ʻia ka maʻi radiation o ka acromegaly inā ʻaʻole hiki ke hoʻōla ʻia a ʻoi aku ka hopena o ka lāʻau lapaʻau, no ka mea ma hope o ka hana ʻana, hana ʻia ke kala ʻana ma hope o kekahi mau makahiki wale nō, a nui ka hopena o ka hōʻemi ʻana i nā hōʻeha radiation.

Hoʻokomo ka prognosis no kēia pathology i ka timeliness a me ka pololei o ka mālama ʻana. ʻO ka hana ʻole o nā hana e hoʻopau ai i ka acromegaly hiki ke alakaʻi i ka maʻi o nā mea maʻi o ka hana a me ka makahiki ikaika, a hoʻonui hoʻi i ka nui o ka make.

Me ka acromegaly, ua hoʻemi ʻia ka manaolana: 90% o nā mea maʻi e ola a hiki i 60 mau makahiki. Hoʻā pinepine ʻia ka make ma muli o ka maʻi o ka maʻi maʻi. ʻOi aku nā hopena o nā hana lapaʻau o ka acromegaly me ka liʻiliʻi o nā adenomas liʻiliʻi. Me nā nunui o ka kelepona pituitary, ʻo ke alapine ʻana o kā lākou mau kahe e hoʻonui mālie.

Hoʻokomo ʻia ka pale ʻana o ka acromegaly i ka nānā mua ʻana i ka hana hoʻonā ʻana i ka hormonal. Inā i ka manawa e hoʻomaʻamaʻa i ka hoʻonui ʻia ʻana o ka hānai o ka ulu ʻana o ka hormone ulu, hiki iā ʻoe ke pale i nā loli pathological i loko o nā kino o ke kino a me ka helehelena, e hoʻomau i ka kala mau mau.

Pākuʻi ʻia ka pale a me ke kau ʻana i nā ʻōlelo aʻoaʻo penei:

pale i nā hōʻeha poʻo ʻeha,
e ʻōlelo aku i kauka no ka maʻi ma waena o ka maʻi kuʻuna,
mālama pono i nā maʻi e hoʻopilikia ai i nā kino o nā ʻōnaehana o ka ʻōpū,
pono ka hānai o nā keiki a me nā pākeke e hoʻopiha i nā mea pono e pono ai.

ʻO Acromegaly kahi maʻi o ka gland pituitary i hoʻopili ʻia me ka hoʻonui nui o ka ulu ʻana o ka hormone hoʻoulu - somatotropin, i hiʻohiʻona e ka ulu nui o ka ʻōpū a me nā ʻōpū o loko, ka hoʻonui ʻana o nā hiʻohiʻona a me nā ʻāpana ʻē aʻe o ke kino, ka maʻi metabolic. Hoʻomaka ka maʻi ʻana i ka wā i pau ai ka ulu ʻana o ke kino maʻamau. I ka wā mua, ua loli a loli ʻole ʻia nā loli a me ke ʻano. Ke hala nei ʻo Acromegaly i kahi lōʻihi - ke piʻi aʻe nei nā hōʻailona, a ʻike ʻia nā loli o ka helehelena. I ka awelika, 5-7 makahiki mau lemu mai ka hoʻomaka ʻana o nā hōʻailona mua o ka maʻi i ka maʻi ʻana.

Hoʻopilikia ka poʻe o nā makahiki pākēneka i ka acromegaly: ma ke ʻano he kānāwai, ma ka manawa o 40-60 mau makahiki, ʻoi aku ka kāne a me ka wahine.

Nā hopena o ka somatotropin ma luna o nā kino kanaka a me nā ʻili

ʻO ka mea huna o ka ulu ulu ʻana - e mālama ana i ka hormone ulu - e lawe ʻia ana e ka kelepona pituitary. Hoʻoponopono ia e ka hypothalamus, ka mea, inā pono, hana ia i ka neurosecretions somatostatin (ke kāohi nei i ka hana o ka ulu ulu) a me somatoliberin (hana iā ia).

I ke kino o ke kanaka, ʻo ka ulu ʻana o ka hormone hoʻoulu i kahi ulu linear o ke kāʻei o ke keiki (i.e., kona ulu i ka lōʻihi) a nāna ke kuleana kūpono i ka ʻōnaehana musculoskeletal.

I ka poʻe pākeke, kahi i komo ai kekahi somatotropin i ka hana metabolism - ua haʻi ʻia ka hopena anabolic, e hoʻoikaika ana i nā ʻōnaehana synthes, e kōkua ana i ka hoʻēmi ʻana o ka momona ma lalo o ka ʻili o ka hoʻomaʻamaʻa ʻana, e hoʻolōʻihi i ka ratio o ka māhina a me ka momona momona. Eia kekahi, mālama pū kēia hormon i ka metabolismo kalaiʻa, ʻo ia kekahi o nā contra-hormonal hormones, i.e., e hoʻonui ana i ka pae o ka glucose i ke koko.

Aia ma laila he hōʻike nō ka hopena o ka ulu ulu ʻana me ka immunostimulate a me ka nui o ka hoʻoliina ʻana o ka calcium ma ka iwi iwi.

Nā kumu a me nā mīkini hana acromegaly

I ka 95% o nā hihia, ʻo ke kumu o ka acromegaly he pūpū hipoki - he adenoma, a i ʻole somatotropinoma, e hāʻawi ana i ka hoʻonui ʻia ʻana o ka lāʻau ulu ulu. Eia kekahi, hiki i kēia maʻi maʻi me:

ke ʻano o ka hypothalamus, hoʻonāukiuki i ka hoʻoulu ʻana o somatoliberin,
mahuahua i like me insulin-like ulu ulu ulu,
hypersensitivity o nā kiko i ka hormone ulu ulu,
pathological secretion o ka ulu ulu ana i loko o nā kino o nā kūloko (ovaries, māmā, bronchi, nā lālā o ka gastrointestinal tract) - ehi kōkia.

E like me ke kānāwai, ulu ka acromegaly ma hope o nā hōʻeha o ka pūnao o ka pūnao o nā kikowaena, nā maʻi maʻi infectous a i ʻole-infectious.

Ua hōʻike ʻia ua loaʻa pū ka poʻe i loaʻa i kēia pathology mai ka acromegaly pinepine pinepine.

Hōʻike ka hoʻololi ʻana o ka Morologegaly i ka acromegaly e ka hypertrophy (hoʻonui i ka nui a me ka lehulehu) o nā kiko o nā kino o loko, ka ulu ʻana o nā kiko huakaʻi i loko o lākou - ke hoʻololi nei kēia mau hoʻololi i ka hiki ke hoʻomohala ʻana i nā neoplasms benign a malignant i ke kino o ka mea maʻi.

Nā hōʻailona pili i kēia maʻi.

pālahalaha o nā lima, wāwae,
ka hoʻonui ʻana o ka nui o nā hiʻohiʻona pilikino - nā ʻōpū nui, ka ihu, ka ʻōlelo, aia nā lūlū niho), ka pālahalaha lalo ʻana o nā ʻili, nā puʻu ma waena o nā niho, nā ʻili o ka ʻili ma ka lae, ka lipolo nasolabial e lilo ka hohonu, hoʻololi ka ʻōpū. ,
leo leo leo
poʻomanaʻo
paresthesia (ka manaʻo o ka hoʻāhu, ke nānā ʻana, nā mea kolo maoli i nā ʻāpana like ʻole o ke kino),
ʻeha i ke kua, ko nā ʻuʻuku, ka palena o ka hooweliweli ʻana,
kaohuu
ka ʻōpū ʻana o nā ʻōpū kuʻuna a me ke alo,
luhi, hoʻemi ʻia ka hana
huki, luwelu (he mau hōʻailona o ka neʻe ʻana o ke kaomi intacranial nui me ka nui o ka ʻīnike kaniki)
ʻōpū o nā ʻōpū
nā maʻi hōʻeha
ka hoʻemi ʻana o ke kaʻa kahe a me ka palulu,
ʻike maka (ʻike maka, ʻelua makaʻu ke aniani)
luhi a me ka nalo ana
ka pau ʻana o ka waiū mai nā laumalia hanala - galactorrhea,
hōʻeha nui ma ka puʻuwai.

ʻO kahi hōʻike hoʻokolohua o kahi mea e loaʻa ana i ka acromegaly, e ʻike ke kauka i nā loli i kēia aʻe nei:

Eia hou, e nānā ke kauka i ka nui o nā hiʻohiʻona nānā a me nā mea nui,
deformations of the bone skeleton (curvature of the spine, barela-ʻano - hoʻonui ʻia i loko o ka anteroposterior nui - umauma, hoʻonui i waena o ka intercostal luna).
ka ʻōpū o ka maka a me nā lima,
kaohuu
Holeʻohiʻi (hoʻonui ʻia ke ulu ʻana o ka lauoho kāne i ka wahine),
ka nui o ka nui o ka nui o ka glid thyroid, ka puʻuwai, ka puʻuwai a me nā mea ʻokoʻa ʻē aʻe.
myopathy proximal (i.e., nā hoʻololi i loko o nā ʻiʻo i pili i ka pili kokoke i ke kikowaena o ka ʻala).
koko koko kiʻekiʻe
ana ka lihilihi ma kahi electrocardiogram (nā hōʻailona o ka puʻuwai ʻonama acromegaloid),
kiʻekiʻe ka prolactin pae i ke koko,
ka hopena o ka metabolic (ma kahi hapa o nā poʻe maʻi he mau hōʻailona o ka maʻi mellitus, kūʻai (paʻa, paʻa ʻole) i ka maʻi hypoglycemic, me ka hoʻomalu ʻana o ka insulin).

Ma 9 mai 10 mau mea maʻi me ka acromegaly i kāna hoʻomohala hanana, ʻike ʻia nā hōʻailona o ka hiamoe apnea syndrome. ʻO ka manaʻo o kēia kūlana, ʻo ia ma muli o ka hypertrophy o nā kiko palu o ka pākuʻi ʻana o ka ʻōpū o ka ʻaoʻao kiʻekiʻe a me kahi hana hewa o ke kikowaena o ka ʻōpū o ke kanaka, pōʻai paʻa pōkole pōkole i ka wā o ka hiamoe.ʻO ka mea maʻi iā ia iho, ma ke ʻano kānāwai, ʻaʻole ia e manaʻo iā lākou, akā mālama pono nā ʻohana a me nā hoa aloha o ka mea maʻi. Hōʻike lākou i ka hana ʻana i ka pō, i ʻaole ʻia e ka paule, i ka manawa o ka neʻe o ka ʻōpū o ka puʻuwai o ka mea maʻi. Ke oki aʻe nei kēia mau pila i kahi kekona, ma hope iho ua ala aʻe ka mea maʻi. Nui nā ala awāwa i ka pō ʻaʻole ka hiamoe a ka mea maʻi, hopohopo nui, hopohopo kona manawa, lilo ia i mea huhū. Eia kekahi, aia kahi hopena o ka make ahonui inā hoʻopiʻi kekahi o ka hopu ʻana i ka hanu.

I ka wā mua o ka hoʻomohala ʻana, ʻaʻole i hoʻonā ka acromegaly i ka hōʻeha i ka mea maʻi - ʻaʻole nui loa nā mea maʻi e ʻike koke i ka hoʻonui ʻana i kekahi a i ʻole kekahi wahi o ke kino i ka nui. Ke hoʻomau nei ka maʻi ʻōmaʻomaʻo, ʻoi aku ka maikaʻi o nā hōʻailona, ma ka hopena aia kekahi mau hōʻailona o ka puʻuwai, nā ʻūpū a me nā pulmonary failed. I kēlā me kēia mau mea maʻi, ʻo ka loaʻa ʻana o ke kaʻaelike i ka atherosclerosis, he hypertension he palapala o ka kiʻekiʻe ma mua o nā poʻe e kū ʻole nei i ka acromegaly.

Inā ulu ka adenoma pituitary i kahi keiki inā e wehe mau ana nā wahi ulu o kāna ʻūhā, hoʻomaka lākou e ulu wikiwiki - hōʻike ka maʻi iā ia iho i ka gigantism.

ʻO ka wehewehe pōkole o nā patology

Hoʻokumu ʻia ka Acromegaly, ma ke ʻano he kānāwai, me ka neoplasms tumor i hoʻopaʻa ʻia i ka gland pituitary anand, kuleana no ka hoʻokumu ʻana i ka ulu ulu. I ka poʻe maʻi e hōʻeha nei i kēia alaʻai, ua loli nā hiʻohiʻona nānā (nui aʻe), hoʻonui i ka lima a me ka nui o ka wāwae. Eia kekahi, ʻo ka kaʻina pili pathological i hui pū ʻia me ka ʻehaʻeha a me nā hōʻeha, ke kuʻi nei ka hewa ma ka ʻōnaehana.

He mea nui ia! ʻO kēia maʻi, e like me acromegaly, pili wale i nā mea maʻi. Hoʻomaka ka pathology ma hope o ka wā ʻōpiopio a me ka ulu ʻana o ke kino!

Wahi a nā helu helu, ʻike nui ʻia nā mea maʻi ma ka helu makahiki mai 40 a 60 mau makahiki i ka acromegaly. Hōʻike ʻia ke kaʻina hana i ke ala lāʻau kūlike, lohi. I ka nui o nā hihia, ʻike ʻia ka maʻi ma hope o 6-7 mau makahiki mai ka hoʻomaka ʻana o kona hoʻomohala ʻana, ka mea i hoʻopiʻi pono i ka mālama ʻana ma hope.

Hoʻomaʻamaʻa nā kauka i nā papa i hope aʻe o ke kūkulu ʻana o ke kaʻina pili:

I ka papa mua, hele mai ka maʻi ma kahi ʻano laten, laten, a me nā loli ke hiki ke ʻike ʻia e ka tomography compute o ka lolo.
Ma kēiaʻano, hōʻike ka hōʻailona mana i nā hōʻailona me ke kūkaʻi maoli.
I ke kolu o ke kolu, he nui ka piʻi ʻana o ka neoplasm ka ʻū e kū nei ma ka pihi gituitary anand. Ma ka manawa like, ke koi ʻia nā ʻāpana o ka lolo, ka mea e hōʻike ai i nā hōʻailona, e like me ka ʻike ʻana ʻana o ka ʻike, nā pilikia nū, a me ka hoʻonui ʻana o ke kaomi intacranial.
Hōʻike ʻia ka hana hope loa o ka acromegaly e ka hoʻomohala ʻana o ka cachexia a me ka hoʻohemo hou ʻana i ke kino o ka mea maʻi.

Hoʻonui ka hoʻonui ʻana i ka ulu ʻana o ka hormone ulu i ka hoʻomohala ʻana o nā maʻi cardiovascular, pulmonary a me ka maʻi oncological, ʻo ia ke kumu o ka make ʻana o nā poʻe maʻi e hōʻeha nei i ka acromegaly.

Pākuʻi a me ka pale ʻana o ka acromegaly

Ma ke ʻano o ka mālama ʻole ʻana, make ʻole ka prognosis, loaʻa i nā maʻi he ola i ʻekolu a ʻelima mau makahiki, me ka gigantism congenital, ʻike pinepine ʻole ka poʻe i ka iwakālua ma mua o ka puka ʻana o nā lāʻau lapaʻau. Hiki i nā ʻenehana o kēia mau lā ke pale i ka hoʻoneʻe o ka ulu ulu ʻana a hōʻemi paha i ka hoʻowili ʻana o ke kino iā ia. I kekahi manawa hoʻopau loa i ka ʻōpūua lilo i kumu kumu. No laila, me ka lāʻau kūpono, hiki i ka prognosis ke piʻi i 30 mau makahiki o ke ola, akā koi mau ʻia ka mālama mālama mau. ʻO ka hapa nui o nā mea maʻi he palena iki.

Hōʻalo ʻia nā maʻi maʻamau a me nā mea paʻakikī loa, no ka mea ʻaʻohe kumu hoʻokahi no ka hoʻomaka ʻana o ka acromegaly. Hiki i nā palapala mai ke kauka ke ʻōlelo aʻo pale aku i nā hōʻeha poʻo, a no ka poʻe i loaʻa i kahi ʻokaʻaka, kipa i ka neurologist a me ka endocrinologist no nā makahiki he nui ma hope o kahi ulia, e ʻae ʻoe e ʻike i nā loli o nā pathological i ka kelīpipi hipipi i ka manawa mua.

ʻO ka hana o ke kūkuluʻana a me nā kumu kumu o ka acromegaly

ʻO ka maʻamau, ka liʻiliʻi o ka ʻikepili somatotropin i ke koko i ka wā o ka lā, hiki i kona kiʻekiʻe ma nā hola kakahiaka. I ka poʻe maʻi me ka acromegaly, ʻaʻole wale ka mea e hoʻonui ai i ka kao ʻana o ka STH i loko o ke koko, akā ua pale pū ʻia i ka ritika maʻamau o kāna honi. No nā kumu like ʻole, ʻaʻole mālama nā cell o ke aniani pituitary gland i ka mana hoʻoponopono o ka hypothalamus a hoʻomaka e hoʻonui ikaika. Ke alakaʻi ʻana i nā hua o ka nā pituitary i ke ʻano o kahi koena glandular aign - pituitary adenoma, ka mea e ulu ai ka somatotropin. Hiki i ka nui o ka adenoma ke hele i luna o nā kenimika a keu i ka nui o ke aniani ponoʻī, ʻae me ka luku ʻana i nā cell pituitary maʻamau.

ʻO nā hoʻokō o Acromegaly

He aha ka pilikia o ka pathology?

Hoʻopili i kahi mea i hōʻoki ʻia e ka acromegaly pono i ke ʻano o ka mea maʻi a hōʻemi nui loa i ke ʻano o kona ola, i ka loaʻa ʻole o ka hoʻomaʻamaʻa kūpono, hiki i kēia ʻano ke hoʻonāukiuki i ka hoʻomohala ʻana o nā hoʻopiʻi weliweli loa.

I ka nui o nā hihia, e alakaʻi ka lōʻihi o ka acromegaly i nā hiʻohiʻona o nā maʻi e like me kēia:

nā hana hōʻeha o ka gastrointestinal tract,
nā maʻi kūwaho
ke ʻano o ka ʻoihana endocrine,
ʻoi ka pelekikena adrenal
nā fibroids
polyps pōpilikia
hoʻōla
ʻlelo maʻi
maʻi maʻi coronary artery
puʻuwai paʻakikī
haehae maʻi.

E nānā:Ma kahi kokoke i ka hapalua o nā mea maʻi me ka acromegaly he hoʻopiʻi e like me ka maʻi mellitus.

ʻO nā hewa o ka nānā a me ka auditory hana i nā hiʻohiʻona o kēia alaʻala e hiki ai ke kamaʻilio piha pono a me ka makapō o ka mea maʻi. Eia kekahi, ʻaʻole hiki ke loli ia mau loli.

Hoʻonui nui aʻe ʻo Acromegaly i nā hōʻeha o ke ʻano o nā neoplasms malignant tumor, a me nā ala like ʻole o nā kino o loko. ʻO kekahi hoʻopiʻi ʻano hoʻoweliweli o ka acromegaly kahi mea hopu i ka hanu o ke ea, ka mea nui e loaʻa i kahi kūlana hiamoe.

ʻO ia ke kumu e makemake ai ka mea maʻi e hoʻopakele i kona ola, i ka wā i ʻike ʻia nā hōʻailona mua e hōʻike ana i ka acromegaly, pono nō e ʻimi i ke kōkua ʻoihana mai kahi loea akamai - he endocrinologist!

Pehea e hoʻomaopopo ai i ka maʻi?

I ka nui o nā hihia, hiki paha i kahi loea ke kānalua i ka nohoʻana o ka acromegaly i ke ʻano o ka mea maʻi, nā hōʻailona ʻano a i ka wā o ka nānā ʻana o ka mōʻaukala i ʻohi ʻia. Eia naʻe, e hana i kahi maʻi kūpono, hoʻoholo i ka pae o ke kaʻina pili a me ka nui o ka hōʻino i nā kino o loko, ua kuhikuhi ʻia nā mea maʻi i kēia mau hōʻike laikini.

He mea nui ia! ʻO ke kumu nui o ka diagnostic mea ʻo ke kāohi ʻana o ka hormone ulu e hoʻohana ana i ka glucose. Inā hana pinepine nā kelepona pituitary i ke kūmole, hoʻōla ka glucose i ka hōʻemi o ka nui o ka nui o ka hormone ulu, ke ʻole ʻokoʻa ka kiʻekiʻe o ka hormone, ke kūʻē aʻe.

E hoʻomaopopo i ka hoʻopiʻi ʻana i nā hoʻonāukiuki i hoʻonāukiuki ʻia e ka hoʻomohala ʻana i nā acromegaly, ua mālama ʻia kēlā me kēia hana hoʻonaninani hou.

Ma hope o ka hoʻokō ʻana i kahi maʻi ākea ākea, ʻaʻole hiki i ka mea loea ke hana i kahi maʻi pololei, akā hōʻike nō hoʻi i ka loaʻa ʻana o nā maʻi concomitant, e ʻae ana i ka mea maʻi e hāʻawi ʻia i ka papa lāʻau lapaʻau kūpono piha loa a kūpono no kahi hihia.

Nā Hana Hoʻolaha Acromegaly

ʻO ka hana nui o nā kauka i ka maʻi maʻi o ka acromegaly e hoʻokō i ka kala mau ʻana, me ka hoʻokaʻawale i nā ʻōnaehana o ka ulu ʻana o ka hormone hana.

Hiki ke hoʻohana ʻia nā hana i hala no kēia mau pahuhopu:

lawe i nā lāʻau lapaʻau
ehi radiation
hoʻokō ʻana.

He mea nui ia! I ka nui o nā hihia, ʻo kahi hakakā maikaʻi e kūʻē i kēia maʻi e pono ai ka hui hoʻohui pū ʻana.

Nā ʻano kumuwaiwai

No ka hoʻopaʻa ʻana i ka ulu nui o ka ulu ʻana o ka ulu ulu, ua kuhikuhi ʻia nā mea maʻi i kahi papa o ka lāʻau hormone e hoʻohana ana i nā analog somatostatin. Ua hōʻike pinepine ʻia nā poʻe maʻi i ka lāʻau like e like me Bromocriptine, e kuhikuhi ana i ka hana ʻana i dopamine, i kaomi ʻana i ka synthesis o ka hormone somatotropin.

Ma mua o nā hoʻopiʻi ʻano a me nā maʻi concomitant, e lawe ʻia ana ka maʻi hōʻailona maʻi kūpono, kahi hoʻolālā hana i hoʻomohala ʻia no kēlā me kēia maʻi pākahi.

Ua hōʻike ʻia ka hoʻohana ʻana o ka maʻi radiation i nā hopena maikaʻi.. ^ E Ha yM. ʻO kēia kaʻina ke hopena i ka wahi i hōʻino ʻia o ka kelepona pituitary e nā hihi gamma kikoʻī. Wahi a nā hōʻike helu a me nā hoʻokolohua maʻi, ʻo ke kūpono o kēia ʻano ʻo ka 80%!

ʻO kekahi o nā ala hou o ka mālama ʻana i ka lāʻau acromegaly ʻo ka radiotherapy. ^ E Ha yM. Wahi a nā poʻe loea, ʻo ka hopena o ka neʻe o ka x-ray e kōkua i ka hana paʻa ʻana o ka ulu ʻana o nā neoplasms a me ka hana o ka ulu ulu ʻana. ʻO kahi papa holoʻokoʻa o ka x-ray therapy e hiki ai iā ʻoe ke hoʻokō i ka kūlana o ka mea maʻi a hoʻopau i nā hōʻailona ʻano o ka acromegaly, ʻo nā hiʻohiʻona facial o ka mea maʻi i pālulu ʻia.

Ka Hoʻōkuhi Kūʻai Kūʻai

Hōʻike ʻia ka wawaʻi no ka acromegaly no ka nui o ke ana o ka neoplasms, ka piʻi wikiwiki ʻana o ke kaʻina pathological, a me ke keʻole o ka hiki ʻana i nā hana lapaʻau conservative.

He mea nui ia! ʻO ka hana maʻi ʻo ia kekahi o nā alaina e pono ai ke kaohi ʻana i ka acromegaly. Wahi a nā helu helu, 30% o nā maʻi maʻi e hoʻōla mau ʻia nā maʻi, a ma ka 70% o nā maʻi he maʻi hoʻomau, hoʻomau ka lōʻihi.

Hoʻokomo ʻia ka hōʻemi ʻana no ka acromegaly e hana i ka neʻe ʻana o ka neoplasm neʻe i ka pituitary. I nā pilikia paʻakikī, hiki i kahi hana ʻelua a i ʻole kahi papa hana hou o ka lāʻau lapaʻau e pono ai.

Pehea e pale aku ai i nā kulekele?

I mea e pale ai i ka hoʻomohala ʻana o ka acromegaly, ʻōlelo pololei nā kauka e pili i nā ʻōkuhi o kēia mau manaʻo.

pale i nā hōʻeha poʻo ʻeha,
e lapaʻau i nā maʻi hopohopo i ka manawa kūpono,
e ʻōlelo aku i kauka no ka maʻi ma waena o ka maʻi kuʻuna,
mālama pono i nā maʻi e hoʻopilikia ai i nā kino o nā ʻōnaehana o ka ʻōpū,
hana pinepine i nā hōʻike no ka hōʻike ʻana i nā ʻōhumu hormone ulu no nā kumu prophylactic.

ʻO Acromegaly kahi maʻi lohi a weliweli loa, i piha me ka nui o nā hoʻopiʻi. Eia naʻe, ka manawa kūpono o ka hoʻokalakupua a me ka hoʻokō kūpono, hiki i ka mālama kūpono ke loaʻa i ke kala paʻa a hoʻihoʻi i ka mea maʻi i kahi ola piha a maopopo.

Sovinskaya Elena, nānā i ka mea lapaʻau

8,165 mau manaʻo holoʻokoʻa, 3 ʻikeʻike i kēia lā