ʻO nā ʻōlelo aʻoaʻo Gliformin no ka hoʻohana ʻana, contraindications, nā hopena pili, nā loiloi

ʻOiea hypoglycemic aʻalili mai ka hui biguanide.
ʻO ka hoʻomākaukau: GLYFORMIN®
ʻO ka mea ikaika o ka lāʻau lapaʻau: metformin
ATX Encoding: A10BA02
KFG: ʻO ka lāʻau hypoglycemic oral
Ka helu hoʻopaʻa inoa: P No. 003192/01
Lā hoʻopaʻa inoa: 04/21/04
Mea ʻai reg. doc .: Kelaa lāʻau a me ka lāʻau lapaʻau AKRIKHIN OJSC

E hoʻokuʻu i ke ʻano a me ka ʻano

ʻO nā papa ʻōlelo o ka Gliformin nā papa.

ʻO ka mea ikaika o ka lāʻau ka metformin hydrochloride. Hiki i kona paʻa i loko o kahi papa hoʻokahi he 500 mg, 850 mg a i ʻole 1 gram.

ʻO nā mea kōkua o nā papa 500 mg nā calcium phosphate dihydrate, sorbitol, povidone (polyvinylpyrrolidone), waikawa stearic a calcium stearate, macrogol (polyethylene glycol). 60 ke kuai aku ia. i loko o nā pahu pepa (6 mau bele pōpoki me 10 papa o kēlā me kēia.

ʻO nā kumuwaiwai hou o Glyformin 850 mg a me nā 1 papa papa he starch potato, stearic acid, povidone (polyvinylpyrrolidone). I kēia mau poho, ua kūʻai ʻia nā papa 60. i nā kēla polypropylene.

Lapaʻau lāʻau

ʻO ka Metformin kahi lāʻau lapaʻau hypoglycemic waha e pili ana i ka māhele o biguanides. Hoʻemi ia i ka hōʻike kahakaha hyperglycemic, a hoʻemi ʻia ka makaʻala o ka hypoglycemia. ʻAʻole ia e like me derivatives sulfonylurea, ʻaʻole e hoʻoulu ka mea e hana i ka hana o ka insulin a ʻaʻole i hōʻailona ʻia e kahi hopena hypoglycemic i ka wā i hoʻohana ʻia ai i nā mea hana olakino maikaʻi.

Hoʻonui ka Metformin i ka hoʻowalewale ʻana o nā receptors peripheral i ka insulin a hoʻonui i ka hoʻohana ʻana i ka glucose i loko o nā kekela, a mālama pū nō hoʻi i ka gluconeogenesis i loko o ka ate a pale aku i ka hoʻopio ʻana o nā hāmeʻe i loko o ka ʻawaʻawa. Hoʻokomo ʻo Metformin i ka hana glycogen ma o ka hana ʻana i ka synthase glycogen a hoʻonui i ka hiki ke kahe o ka halihali i kekahi ʻano o nā mea ʻoki mīmī.

Hoʻopilikia maikaʻi hoʻi ʻo Glyformin i ka hana lipid metabolism, hoʻemi ʻana i ka neʻe o ka triglycerides, haʻahaʻa lipoproteins haʻahaʻa a me ka cholesterol holoʻokoʻa. E kue ana i kahi o ke ʻano o ka mālama ʻana me ka metformin, ʻaʻole i loli iki ka nui o ke kino o ka mea maʻi, a ua hōʻemi ʻia nō hoʻi.

Lapaʻau lāʻau

Ma hope o ka lawelawe waha, ua hoʻohuihui ʻia ka metformin mai ka digestive tract. Loaʻa kona kūlohelohe kūʻokoʻa 50-60%. ʻO ka lōʻihi loa o ke ʻano o kahi mea i loko o ka plasma ua hiki ke kokoke i nā hola 2.5 ma hope o ka hoʻokele ʻana a ʻo 15 μmol paha, a ʻo 2 μg / ml paha. Ke lawe nei i ka metformin me ka meaʻai, hoʻemi a hoʻoulu ʻia kona ʻano. Hāʻawi koke ʻia ia ma nā kiko o ke kino, ʻaʻole hoʻohālikelike i nā protein plasma.

Metamine nā Metformin i loko iki loa o ka hoʻēmi ʻana. ʻO kāna hoʻomaʻamaʻa i nā limahana olakino he 400 ml / min (ʻo ia ka manawa 4 ʻoi aku ka nui ma mua o ka hoʻopuni ʻana me creatinine), e hōʻike ana i ka loaʻa ʻana o nā mea huna tubular. ʻO ka hapalua hapalua he 6,5 mau hola. Me ka hikiʻole o ka renal, ke hoʻonui nui ʻia, ka mea e hoʻonāukiuki i ka hoʻohui o ka lāʻau lapaʻau.

Nā hōʻailona no ka hoʻohana ʻana

Hoʻolaha ʻia ʻo Gliformin ma ka mālama ʻana o:

Mīkini II nā maʻi mellitus, i ka wā ʻaʻole pono ka lāʻau huikaʻi alāʻauʻai meaʻai,
diabetes type II me ka hoʻohui ʻana i ka lāʻau lapaʻau i insulin.

Nā Hoʻohui

ʻAʻole hōʻike ʻia e lawe i kēia lāʻau me:

coma maʻi maʻi a me nā kūlana precomatous,
ketoacidosis,
nā maʻi ʻohi
lesi nā ate a me nā ʻāʻī,
cardiovascular or cardiopulmonary failed,
myocardial pili hewa
lactation, hapai.

Nā ʻōkuhi no ka hoʻohana ʻana iā Gliformin (Ke ʻano a me ka anaana)

E like me ka hōʻike ʻana e nā kuhikuhi no ka hoʻohana ʻana o Gliformin, lawe ʻia nā papa maʻamau. I kēia hihia, nā lā 3 mua, e kau ʻia nā mea maʻi 500 mg i 3 mau papa lāʻau i ka lā, i ka manawa like ʻole a ma hope o ka ʻai. A laila hoʻonui pinepine ʻia ka dosis i 1 g. ʻO ka maʻamau, ʻo ka mālama ʻana i kēlā me kēia lā he 0.1-0.2 g.

Ke keu

I nā hihia o ka overdose e hele mai lactic acidosishoʻokoe ʻO ke kumu nui no kona hoʻomohala ʻana he cumulation. metformin ma muli o kahi hana renal āpau. I ke ʻano hele mua ʻana. kikala, holo maikaʻi, ʻōpū, nāwaliwali laulā, hōʻemi i ke kiʻekiʻe, ʻeha a me ka ʻehaʻeha, hōʻemi i ke kaumaha, briearrildia. A laila e wikiwiki wikiwiki anaāhāhuʻeʻike naʻau a like me ka hoʻomohala ʻana koma.

Ke hele mai nā hōʻailona lactic acidosis pono ʻoe e haʻalele koke e lawe iā Gliformin. Lawe ʻia ka hana hou i loko o ka haukapila, no laila ke koi nei ka mea maʻi i ka haukapila, hoʻonoho ʻana i ka ʻike o ka lactate, e hōʻoia ana i ka maʻi maʻi. ʻO nā kaʻina hana kūpono hemodialysiske kōkua ʻana e kāpae i ke kino lactate a metformin. ^ E Ha yM. Hoʻohana ʻia nā lāʻau hōʻailona hou aʻe.

Glyformin hoʻokuʻu i ka puka, ka lāʻau lapaʻau me ka hoʻopili.

Ke keʻokeʻo a kokoke paha keʻokeʻo paha nā papa, ʻeleʻele-cylindrical, me ka bevel a me ka notch.

1 kōpō
metformin (i ke ʻano o ka hydrochloride)
250 mg
-«-
500 mg

Nā mea kūlike: sorbitol, calcium phosphate dihydrate, polyvinylpyrrolidone (povidone), polyethylene glycol (macrogol), kalima stearate a waikawa stearic.

10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.
10 kamepiula - nā papaki blister (6) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (10) - nā ʻeke pepa.
60 pcs. - nā kīʻaha o ke aniani o ka aniani (1) - nā pā o ka pahu paʻi.
100 pcs - nā kīʻaha o ke aniani o ka aniani (1) - nā pā o ka pahu paʻi.

KAHANA NUI O NA KANANUI UIKI.
Hōʻike ʻia nā ʻike a pau no ka familiarization wale nō me ka lāʻau lapaʻau, pono ʻoe e kamaʻilio i ke kauka e pili ana i ka hiki ke hoʻohana.

Ke hana lāʻau lapaʻau o ka glyformin

ʻOiea hypoglycemic oral mai ka hui o ka biguanides (dimethylbiguanide). Hoʻopili ʻia ka hana o ka metformin me ka hiki iā ia ke kāpae i ka gluconeogenesis, me ka hoʻomohala ʻana i nā momona momona a me nā mea hoʻoneʻe o ka momona. ʻAʻole hoʻopilikia ka Metformin i ka nui o ka insulin i ke koko, akā hoʻololi i kāna pharmacodynamics e ka hoʻemi ʻana i ka ratio o ka lā i hoʻopaʻa ʻia i ka insulin e wehe manuahi a hoʻonui i ka pae o ka insulin i ka proinsulin. ʻO kahi pilina nui loa i ka hana o ka hana o ka metformin ka mea e hoʻoulu ai i ka uptake glucose e nā puʻupuʻu mus.

Hoʻonui ka Metformin i ka neʻe ʻana o ke koko i ka puʻuwai a hoʻomaikaʻi i ka hoʻololi ʻana o ka maʻi glucose i ka glycogen. Hoʻēmi i ka pae o ka triglycerides, LDL, VLDL. Hoʻoulu ʻo Metformin i nā waiwai o fibrinolytic o ke koko ma o ke kāohi ʻana i kahi mea hoʻoneʻe i ka mea hoʻonāukiuki plasminogen.

ʻO ka dosis a me ke ala o ka hoʻokele lāʻau.

No ka poʻe maʻi ʻaʻole i loaʻa i ka insulin, i nā lā 3 mua - 500 mg 3 mau manawa / lā a i ʻole 1 g 2 mau manawa / lā i ka wā a i ʻole ka ʻai. Mai ka lā 4 a hiki i ka lā 14 - 1 g 3 mau manawa / lā. Ma hope o ka lā 15, ua hoʻoponopono ka ʻai ʻana i ke ʻano o ka glucose i ke koko a me ka wai. ʻO ka papa mālama mālama 100 100 mg mg / lā.

Me ka hoʻohana like ʻana o ka insulin i ka maʻa o nā haʻahaʻa ma lalo o 40 mau ʻāpana / lā, ke ʻano like ka nui o ka nui o ke kumu no ka metformin, aʻo ka hopena o ka insulin e hiki hōʻemi iki ʻia (e nā lā 4-8 mau lā / i kēlā me kēia lā). Inā loaʻa ka mea maʻi ma mua o 40 mau ʻāpana / lā, a laila e hoʻohana ke hoʻohana ana i ka metformin a me kahi hoʻēmi ʻana i ka nui o ka insulin e pono ai ka mālama nui a lawe ʻia i loko o kahi haukapila.

ʻO ka hopena ʻaoʻao o ka glyformin:

Mai ka papa hana o ka kūwea: hiki (ma mua o ka hoʻomaka ʻana o ka mālama) nausea, luaʻi, ka ʻōpū.

Mai ka pūnaehana endocrine: hypoglycemia (ʻo ka nui i ka wā e hoʻohana ai i nā kaha kū hoʻokahi).

Mai ka ʻaoʻao o ka hana metabolism: i kekahi mau hihia - lactic acidosis (pono makemake me ka mālama ʻana).

Mai ka ʻōnaehana hemopoietic: i kekahi mau hihia - megalemia megaloblastic.

Nā maʻi hoʻohālikelike i ka lāʻau lapaʻau:

ʻO ka hōʻeha kino o ka ate a me nā pōpilikia, puʻuwai a me nā ea ʻole, ka hopena o ka hala o ka myocardial infarction, ka waiʻona kūloko, ka maʻi maʻi o ka maʻi maʻi, ka ketoacidosis, ka lactic acidosis (me ka mōʻaukala), ka maʻi maʻi wāwae maʻi, ka hapai, ka lactation, hypersensitivity i ka metformin.

PAHANAʻO MAKAUKAI
Contraindicated ma ka hāpai ʻana a me ka lactation.

ʻO nā ʻōlelo kūikawā no ka hoʻohana ʻana i ka glyformin.

ʻAʻole ia i kuhikuhi ʻia no nā maʻiʻeha o ka maʻi, ka hoʻonāukiuki o nā maʻi maʻi a me ka maʻi maʻi, nā hōʻeha, nā maʻi ʻoiʻi kūlohelohe, a me ka hopena o ka lepo.

Mai hoʻohana ma mua o nā hana ma loko o 2 mau lā ma hope o ka hoʻomaʻamaʻa ʻana.

ʻAʻole ia e hoʻohana i ke metformin i nā mea maʻi ma luna o 60 mau makahiki o kēlā me kēia mea e hana nei i nā hana kino koʻikoʻi, kahi mea i pili ʻia me ka piʻi nui o ka hoʻomohala ʻana i ka waika lactic.

I ka wā o ka mālama ʻana, pono ia e nānā i nā hana renal, ka hoʻoholo ʻana o ka ʻike lactate ma ka plasma e lawe ʻia aku ma kahi o nā manawa 2 i ka makahiki, a me ka ʻano like o ka myalgia.

Hiki ke hoʻohana ʻia ka metformin me ka hui pū me ka olihiluna. I kēia hihia, pono e mālama pono ana i ka pae o ka glucose koko.

Hoʻohana ʻia ka hoʻohana ʻana o ka metformin ma ke ʻano he hui hoʻohui me ka insulin i ka haukapila.

Hoʻohālikelike pū kekahi o nā ʻōhua Gliformin me nā lāʻau ʻē aʻe.

Me ka hoʻohana like ʻana me nā derivatives o sulfonylurea, acarbose, insulin, salicylates, MAO inhibitors, oxytetracycline, ACE inhibitors, me clofibrate, cyclophosphamide, hiki i ka hopena hypoglycemic o metformin hiki ke hoʻonui ʻia.

Me ka hana like me ka GCS, hiki i ka contraceptives hormonal no ka hoʻokūkū waha, adrenaline, glucagon, hormon thyroid, deriviazine derivatives, thiazide diuretics, derivin acid nicotinic, kahi hōʻemi i ka hopena hypoglycemic o metformin i hiki.

ʻO ka hoʻohana pinepine ʻana o ka cimetidine e hoʻonui i ka hopena o ka waikika lactic.

Nā ʻōkuhi no ka hoʻohana ʻana iā Gliformin: ʻano a me ka helu ʻana

Lawe ʻia nā papa Glyformin ma ke alo o ka papa ai a i ʻole ma hope o ka meʻa, me ka nui o ka wai.

Kūkulu ke kauka i ka maʻi a me ka manawa o ka lawelawe hoʻokahi, me ka mālama ʻana i ke kiʻekiʻe o ka kaʻe o ka glucose i loko o ke koko.

I ka hoʻomaka o ka mālama ʻana, ʻo nā lā 10-15 mua, hiki ke kaʻi mai nā 0.5 a 1 g i hoʻokahi manawa i ka lā, a laila, e kau ana i ka pae o ke kō i loko o ke koko, hiki ke hoʻonui iki. ʻO ka dosis mālama, e like me ke kānāwai, ʻo 1.5-2 g i kēlā me kēia lā, mahele ʻia i 2-3 mau pona.

ʻO ka palena loa ʻo Gliformin i kēlā me kēia lā he 3 g.

No nā poʻe maʻi maʻi, ʻo ka nui loa ka ʻokoʻa o ka lāʻau lapaʻau ka 1 g i kēlā me kēia lā.

I ka hihia nui o ka metabolic hoʻohālikelike ʻia, hoʻohaʻahaʻa ʻia ka lāʻau e hōʻemi, ʻoiai e piʻi ka nui o ka lactic acidosis.

Nā hopena hopena

Mai ka ʻōnaehana endocrine: i kahi hihia o ka overdose - hypoglycemia,
Mai ka pūnaehana ʻana: nele o ka momona, ka ʻeha o ka ʻōpū, ke ʻano, ka ʻaha metallic i loko o ka waha, ka ʻōpū ʻana, ka luaʻi, ka lemulewa (ʻo kēia mau hōʻailona ka ʻano no ka hoʻomaka ʻana o ka hana, a laila e ʻano maʻamau ke ʻano).
Mai ka pūnaehana hemopoietic: i kekahi manawa - megaloblastic anemia,
Mai ka ʻaoʻao o ka hana metabolism: me ka lōʻihi o ka mālama ʻana - hypovitaminosis B₁₂, i nā hihia līkika, lactic acidosis,
Nā maʻi kūlou: hāpau ka ʻili.

Inā pili nā hopena ʻaoʻao, pono ia e hoʻopau iki iā Glyformin a kūkā i kahi kauka.

Nā ʻōlelo kikoʻī

Pono e hoʻomaʻamaʻa ʻia ka hoʻomaʻamaʻa ʻana me ka mālama mau ʻana i nā pae glucose koko.

I ka manawa o ka mālama ʻana, pono e hoʻokau ʻia nā haʻawina i kēlā me kēia mahina e hoʻokū i ka pae o ka lactate a me ka creatinine i loko o ke koko koko. Ka kia kiaʻi maikaʻi ʻia ka hana o ka pūpū i nā mea maʻi. ʻAʻole pono ʻo Glyformin e kuhikuhi i nā kāne me kahi pae bun ma mua o 135 μmol / L, no nā wahine - 110 μmol / L.

Hiki ke hōʻemi ʻia nā hopena mai ka hoʻowalewale ʻana e ka hoʻohana ʻana i nā antacids a i ʻole nā antispasmodics.

I ka wā e pono ai ka mālama ʻana e mālama i ka inu ʻona a me nā huahana e loaʻa ana i ka ethanol.

Me ka monotherapy, ʻaʻole i hoʻopilikia ʻo Gliformin i ka hiki ke hoʻokele i nā kaʻa a hana me nā mīkini.

ʻOiai e lawe ana iā Gliformin me nā mea hoʻokele hypoglycemic like, me ka insulin, sulfonylureas, pono e makaʻala i ka wā e hoʻokele ana i nā kaʻa a hana i nā hana pōʻaloʻī e pono ai ke kiʻekiʻe o nā hopena psychomotor a hoʻonui i ka nānā.

ʻŌpū a me ka lactation

Hoʻohana ʻia ka hoʻohana ʻana o ka metformin i ka wā hāpai a me ka umauma.

Ke hoʻolālā nei i kahi hāpai hāpai ʻana, ʻo ia hoʻi inā he mea i mālama ʻia i ka wā o ka mālama ʻana me Gliformin, kāpae ʻia ka lāʻau lapaʻau a hoʻonoho ʻia ke ʻano ʻana o ka insulin.

ʻAʻole i hoʻonohonoho pono i ka hoʻopili ʻana o ka metformin i ka waiū umauma, no laila ʻaʻole pono ke kuhikuhi ʻia ʻo Glyformin i ka wā lactation. Inā he mea nui kāna intake, pono e hōʻoki ʻia ka ʻōpoki.

Hoʻohui nūhou

Hiki iā ia ke hoʻonui i ka hana o Glyformin me ka hoʻohana like ʻana me ka insulin, beta-blockers, sulfonylureas, non-steroidal anti-inflammatory drug, acarbose, monoamine oxidase inhibitors, angiotensin e hoʻohuli ana i ka hoʻohui o nā enzyme, oxytetracycline, cyclophosphamide, a me nā mea ʻē aʻe.

Hiki ke hōʻemi ʻia ka hopena o Gliformin i ka wā e hoʻohana ai i ka glucagon, glucocorticosteroids, oral contraceptives, thyroid hormones, epinephrine, sympathomimetics, "loop" a me ka thiazide diuretics, nā huaʻai o ka acid nikotinic a me phenothiazine.

ʻO ka hoʻohana like ʻana o nā meahana ethanol e loaʻa i ka hoʻomohalaʻana o ka hoʻomehana lactic acidosis.

Holo ka wehe ʻana o Glyformin i ka wā i hui pū ai me ka cimetidine, hiki i ka hoʻomohala ʻana no ka hoʻomohala ʻana i ka waikene lactic acid.

Me ka hoʻokūkū pinepine me nā anticoagulants, derivatives Coumarin, ua hoʻemi ʻia ko lākou hopena.

ʻO nā mea hoʻohālike a Gliformin: Glucofage, Glucofage Long, Glukoran, Gliguanid, Dformin, Diaberit, Diabetosan, Diabexil, Diguanil, Metformin, Melbin, Mellitin, Metiguanid, Modulan, Formmetin.

Hoike e pili ana iā Gliformin

Wahi a nā loiloi o Gliformin, he maikaʻi ia i ka hihia o ka maʻi diabetes mellitus a me nā maʻi pālua. A eia kekahi, hoʻohana pinepine ʻia e nā poʻe maʻi e ʻimi ana e emi ka paona, a aia kekahi poʻe e hoʻohana nei no ia mau mea i ka ʻāpono hiki iā lākou ke haʻa hewa loa i ka kaupaona ʻana a hoʻohiolo i nā pae hormonal. Akā, nui ka poʻe loea e kūʻē i ka hoʻohana ʻana iā Gliformin no ka hoʻolilo ʻana i ka paona, inā ʻaʻohe mākaʻikaʻi koʻikoʻi no kēia.

ʻO kekahi mau mea maʻi e haʻi aku i nā hopena maikaʻi ʻole o ka lāʻau, me ka hōʻeha o ka maʻi, nā nāwaliwali, nā maʻi dyspeptic. Ma muli o ka hiki ke hoʻolōʻihi i ka hopena maikaʻi a me ka maikaʻi i ke kino, ʻoi ʻia e hoʻomau i kahi papa maʻi ma lalo o ka mākaʻi o ke kauka.

ʻO ke kumukūʻai o Gliformin i loko o nā lāʻau lapaʻau

ʻO ke kumukūʻai kūpono o ka papa ʻaina o Gliformin 0.5 g i loko o nā kaula lāʻau lapaʻau he 86-130 mau rubles (ʻo ka pūpū he 60 papa). Oe ke kuai i nā papa i loko o nā kiʻi kiʻi kiʻi me kahi nūnū o 0.85 g no kahi 191-217 mau rubles, a me kahi kaha o 1 g no 242–329 rubles (aia kēlā me kēia mahele he 60 mau papa).

Gliformin: nā kumukūʻai i nā lāʻau lapaʻau pūnaewele

GlyFORMIN 500mg 60 mau pcs. pani ʻ -lelo ʻlelo

ʻO nā papa kiʻi ʻoniʻoni o Gliformin 0.85 g 60 mau pcs.

Hoʻonaʻauao: Rostov State Medical University, kūikawā "General Medicine".

Hōʻike nui ʻia ka ʻike e pili ana i ka lāʻau lapaʻau, i hoʻolako ʻia no ka hana ʻike a ʻaʻole hoʻololi i nā ʻōlelo aʻoaʻo. Hoʻopilikia ka lāʻau-pono iā ia ke olakino!

Wahi a nā noiʻi, ʻo nā wahine e inu i kekahi mau aniani o ka pia a i ʻole ka waiwa i ka hebedoma i loaʻa ka nui o ka loaʻa ʻana o ka umauma umauma.

Wahi a nā kānaka ʻepekema he nui loa ka hoʻohana ʻana i nā mea ʻona no ka poʻe.

I ka hoʻāʻo e hoʻokuʻu aku i ka mea maʻi i waho, ua holo lōʻihi loa nā kauka. No laila, eia no kekahi, ʻo Charles Jensen kekahi i ka wā mai 1954 a 1994. pakele i ʻoi aku ma kahi o 900 hana neoplasm hana hoʻoiho.

I ka wā e ola ai ka mea, ʻo ka mea maʻamau e hoʻomālamalama ma mua o ʻelua mau loko wai nui.

ʻEhā mau ʻāpana pōpokiʻeleʻele he ʻelua haneli haneli. No laila inā ʻaʻole ʻoe makemake e hoʻomaikaʻi ʻoi aku ka maikaʻi, ʻoi aku ka maikaʻi o ka ʻai ʻana ma mua o ʻelua mau lobule i hoʻokahi lā.

Wahi a nā helu helu, ma Lāpule, piʻi ka nui o nā hōʻeha o hope i ka 25%, a me ka hopena o ka hōʻeha ʻana o ka puʻuwai - ma ka 33%. E makaʻala.

Hoʻohui i nā poʻe, hoʻokahi wale nō mea ola ma ka honua honua - ʻīlio, i loaʻa ka prostatitis. He mau hoaaloha maoli nō kēia.

Meliila a keu ka hānau ʻana, ola a make a puna i kā mākou puna. Hiki ke ʻike ʻia lākou ma ka hoʻonui ʻana nui, akā inā i hui pū ʻia, e kūpono lākou i loko o kahi kīʻaha kīkaha maʻamau.

Ua hana ka poʻe ʻepekemaʻAmelika i nā hoʻokolohua ma nā kaole ka hopena a paʻa ka wai wai melemele i ka hoʻomohala ʻana i ka atherosclerosis o nā kīʻaha koko. Hoʻokahi kekahi pūʻulu o nā kiʻi i ka wai anuanu, a ʻo ka lua o ka wai wai kinawai. ʻO ka hopena, ua kaʻawale nā ipu o ka hui lua i nā kolika poli o ka kolamu.

Ke kihi nei nā mea aloha, e nalo ana kēlā me kēia o 6.4 kcal i hoʻokahi minuke, akā i ka manawa like a hoʻololi lākou i ka like o 300 mau like o nā like ʻole.

Hoʻohana ʻia ka poʻe maʻamau i ka ʻaina kakahiaka maʻamau no ka liʻiliʻi loa.

Ke "holo nei ke koko kanaka" ma o nā moku ma lalo o ka pīhoihoi nui, a inā i uhai ʻia kona kūpaʻa, hiki iā ia ke pana a 10 mau mika.

ʻO ka hapa maʻamau o nā hema no ka liʻiliʻi o nā pono.

Ma UK, aia kekahi kānāwai e like me ka mea e hiki ai i ka mea maʻi ke hōʻole e hana i ka hana ma ka mea maʻi inā ulaula a i ke kaupaona ʻana. Pono ke kanaka e haʻalele i nā hana ʻino, a laila, ʻaʻole paha, ʻaʻole pono ia e kāpili ʻia.

ʻO ka paona o ka lolo o ke kanaka e pili ana i 2% o ka nui o ke kaupaona kino, akā e hoʻopau iā ia ma kahi o 20% o ka oxygen e komo ana i ke koko. ʻO kēia mea hana i nā ʻili o ke kanaka i maʻalahi e hōʻino ʻia e ka ʻoliʻoli ma muli o ka nele o ka oxygen.

Ua ʻike ʻia ka aila ʻaila i nā makahiki he mau makahiki, a i loko o kēia manawa ua hōʻoia ʻia e kōkua ana e hōʻoluʻolu i ka mumū, hōʻoluʻolu i ka ʻāʻōlelo, e hoʻomaikaʻi i ka sos.

ʻO ka helu a me ka hoʻokele ʻana o Gliformin

Ma ke kānāwai, kau ke kauka i ka hopena o Glyformin kū hoʻokahi, e pili ana i ka pae o ka glucose i ke koko.

Hoʻomaka hoʻomaka ka mālamaʻana i ka hoʻohanaʻana o 0.5-1 g i ka lā. Wahi a ka pae glycemia, hiki i ka hopena ke hoʻomaka e hoʻonui ma hope o nā lā 10-15.

ʻO ka papa hana mālama ʻia i kēlā me kēia lā he 1-2 papa o Gliformin 1000, e manaʻo ʻia ia e hoʻokaʻawale i nā helu he nui, hiki ke hoʻemi i ka hōʻeha o nā hopena ʻaoʻao e pili ana i ka indigestion.

ʻO ka pae ʻana loa i kēlā me kēia lā he 3 mau papa o Gliformin 1000, eia naʻe, ke kuhikuhi ʻia nei lawe nā poʻe ʻelima iʻoi aku ma mua o 1 g o ka lāʻau.

Me ka overdose o Gliformin, hiki i ka lactic acidosis ke ulu me kahi hopena o ka hopena, nā hōʻailona mua o ka maʻi nausea, hoʻohaʻahaʻa ka nui o ke kino, nāwaliwali nui, ka maʻi palu, ka hāpuka, ka ʻōpū a me ka ʻōpū, ka bradyarrhythmia, hoʻemi i ke koko, puhaluhi, ʻike naʻau, hoʻonui i ka hanu a me ka hoʻomohala ʻana i ka coma. . ^ E Ha yM.

Nā kuleana a me nā kūlana e waiho ai

No ka piha o Gliformin i nā hua lāʻau lapaʻau hypoglycemic papa inoa (papa helu B) me ka ola o ka papa i ʻōlelo ʻia ma lalo o nā waiho mālama (i nā wela a hiki i 25 ° C):

Me kahiʻike o 250 mg a me 500 mg o ka mea ikaika - 3 mau makahiki,
Me kahiʻike o 850 mg a me 1000 mg o ka mea ikaika - 2 mau makahiki.

ʻAoʻi no ka hoʻohana ʻana i nā papa

ʻO nā ʻōpana no ka hoʻohana ʻana i ka lāʻau lapaʻau ka type 2 diabetes mellitus, inā he ʻai koʻikoʻi a me nā hui o ka hui ʻo sulfonylurea, ʻaʻole i loaʻa ka hopena i makemake ʻia. Ua kuhikuhi ʻia ʻia ʻo Glyformin no ka maʻi maʻamau i ka lā 1 ma kahi kokoke i nā inikini insulin.

I ka wā o ka mālama ʻana, pono ke nānā ʻia ka hana o nā pēpē, i ka liʻiliʻi o kēlā me kēia 6 mau mahina ʻoi aku ia i ka nānā ʻana e hoʻoholo ai i ka lactate i loko o ke koko koko.

Hiki ke inu ʻia nā papa i ka wā ʻai a ma hope o ka ʻaina, pono ke kuhikuhi ʻia ka nui o ka lāʻau kauka e ka mea hele mai i ke kauka, e noʻonoʻo ana i nā hopena o kahi hōʻike koko koko.

i ka hoʻomaka ʻana o ka hoʻōla, ʻaʻole nui ka nui o ka mahele ma mua o ka 1 mau grika no ka lā,
ma hope o 15 lā, ua hoʻonui ʻia ka nui o nā kālā.

Pono e uku ʻia ka nui o ka hoʻoponopono mālama ʻia ma mua o 2 mau greka no kēlā me kēia lā, pono ia e hoʻohele ʻia i nā ʻōmole he nui. Hana ʻia nā maʻi o ke ʻano kiʻekiʻe o kēlā me kēia lā e lawe i ka nui o ka 1 gr o ka lāʻau.

Inā hoʻoholo kekahi kauka iā Gliformin no ka maʻi maʻi, pono ke ʻike e hiki i ka poʻe maʻi ke hōʻeha i nā ʻano hopena maikaʻi ʻole o ke kino. Ma ka ʻāpana o ka ʻoihana endocrine, ulu ka hypoglycemia, ma ka ʻaoʻao o ke kahe o ke koko, hiki i ka anemia, ma ke ʻano o ka hōʻemi o ka metabolism ka hopena. Penei ke ʻano o ke kino i nā lāʻau lapaʻau me nā hopena kūloko:

Mai nā lālā o nā wahi o ka gastrointestinal aia kahi hewaʻole o ka makemake, ka maʻiʻeha, ka luaʻi ʻana, ka ʻaʻa metala i loko o ka waha.

Inā he hewa ʻino kekahi, e hōʻike ʻia ana no ka hōʻole ʻana i ka hana me Gliformin, e nīnau aku i kahi kauka.

Hiki ke hoʻohana ʻia ka lāʻau lapaʻau ʻo Glyformin (i kāna mau ʻōlelo aʻo i ka Pūnaewele) no ka hiki ke hoʻololi 'ole hou ʻana, akā i ka mea e pau ai ka piʻi ʻana o ka acidosis lactic. Ma kēia hihia, ʻike pono ʻia ka hana o ka keiki (ma ka liʻiliʻi o hoʻokahi manawa i ka 3-6 mau mahina), i ka wā e hoʻokaʻawale ke kihalakeke i ka pae o 45 ml / min, hoʻopau koke ka mālama ʻana.

Inā hōʻemi ka hana o ke keiki i ka maʻi maʻi maʻi maʻa, pono ke hoʻoponopono ʻia ka nui o ka metformin.

Nā Contraindications, ka pili ʻana o ka lāʻau lapaʻau

ʻAʻole ke ʻōlohelohe ʻo Gliformin no ka ketoacidosis, nā maʻiʻeha o ka maʻi maʻi, ka maʻi maʻi maʻa, ka puʻuwai, ka nele ʻana o ka maʻi, i ka wā hāpai ʻana, ka hoʻouluulu ʻana, ka myocardial infarction, ka mālamalama nui loa i nā ʻāpana o ka lāʻau.

Lawe maikaʻi ka mālama i ka lāʻau no ka maʻi o ka etiology infectious, ma mua o ka mālama ʻana i ka mālama maʻi koʻikoʻi.

Hiki ke emi paha ka hopena o ka lāʻau me ka hopena like ʻole:

Nā lāʻau lapaʻau glucocorticosteroid
ʻO nā hormones thyroid
hoʻoiho
hoʻōla nicotinic
i ka wā e lawe aku ai i nā mea hoʻohālikelike waha.

Inā hui pū ʻia ka metformin me ka insulin, derivatives sulfonylurea, nā lāʻau anti-inflammatory non-steroidal, a me nā beta-blockers, loaʻa kahi kūpono i ka hoʻonui i kona hopena.

ʻO ka wā lōʻihi ʻo Gliformin

I kekahi mau hihia, hōʻike ʻia ke ahonui me ka maʻi maʻi maʻi Gliformin i lōʻihi - Gliformin hoʻolōʻihi. Lawe ʻia ia me nā mea pono o ka wai. Hiki i ka paahana ke kōkua i kona iho a i ʻole ʻāpana o ka hui pū ʻana.

Inā ʻaʻole i lawe ka mea maʻi ma mua me ka metformin, ua ʻōlelo ʻia ʻo ia i ka pā mua o 750 mg hoʻokahi i ka lā. Ma hope o 2 mau pule, e hoʻoponopono ke kauka i ka dosage (e lawe i 2 mau papa o 750 mg), e pili ana i nā hopena o nā hōʻike gula. Me kahi piʻi lohi i ka nui o ka lāʻau, loaʻa ka emi ʻana i nā hopena maikaʻi ʻole mai ka papa hana ʻana, pono, e nalo aku ka maʻi pākia.

Inā ʻaʻole ʻae ʻia ka lāʻau i ʻōlelo ʻia e hoʻokō i ka kaohi maʻamau o ka pae glycemia, pono ia e lawe i ka nui loa ma ke ʻano o ka lāʻau lapaʻau - 3 papa o 750 mg Prolong i hoʻokahi manawa i ka lā.

ʻO nā maʻi Diabetics e lawe i ka metformin i ke ʻano o ka lāʻau lapaʻau maʻamau-maʻamau.

inu inu Prolong ma ke ʻano like,
inā e lawe lākou i mua o 2000 mg, ke hoʻololi ʻia ʻana o ka loli i kahi mana lōʻihi o ka lāʻau lapaʻau.

No ka hoʻokō ʻana i ka mana glycemic loa, ua hoʻohana ʻia ka metformin a me ka hoʻāneʻana o ka hormone manuahi e like me ka mālama hui. ʻO ka mea mua, e lawe i kahi maʻa maʻamau o nā lāʻau lapaʻau (1 papa 750 mg) i ka wā pāʻina, a me ke ʻano o ka insulin e pono e koho ʻia hoʻokahi, e pili ana i ke kō o ke koko.

Ka nui o ka lā, ʻae ʻia ka lawe ʻana ʻaʻole iʻoi aku ma mua o 2250 mg o ka lāʻau lapaʻau, hōʻike ʻia nā loiloi a nā kauka, me ka mālama pono o ke ʻano o ke kino, hiki ke hoʻololi i ka lawe ʻana i ka lāʻau me ka hoʻokuʻu maʻamau o metformin i loko o kahiʻu o 3000 mg.

Loaʻa i hala i ka mea maʻi ke lawe i ka lāʻau lapaʻau, ma ia hihia ke hōʻike ʻia nei e lawe i ka papa ʻaoʻao o ka lāʻau lapaʻau i ka manawa maʻamau. ʻAʻole hiki iā ʻoe ke ʻai i ʻelua pālua o ka metformin, e lilo kēia i ka hoʻolālā ʻana o nā hopena kūlohelohe maikaʻi ʻole, hoʻonui ʻia nā hōʻailona o ka maʻi maʻi, ʻaʻole e ʻae ʻia.

Ponoʻo Glyformin Prolong e lawe i kēlā me kēia lā, pale i nā wāwahi.

Pono ka mea maʻi e hoʻomaopopo i ke kauka hele e pili ana i ka pau ʻana o ka hoʻōla, ʻike iā ia.

ʻO ka ʻōlelo, nā loiloi o nā kauka

Ma muli o ka hele ʻana o nā contraindications, ʻaʻole kūpono nā lāʻau lapaʻau no nā mea maʻi he nui, ma ia mea e pono ai ke koho i nā analogues o ka lāʻau lapaʻau, loaʻa nō hoʻi iā lākou kahi ʻano like o nā mea ola (250, 500, 850, 1000). Hiki i Gliformin ma luna o kahi pā me nā lāʻau lapaʻau:

ʻO ka maʻi Diabetics ua lawe ʻē i ka hana Gliformin e hōʻike ana i kahi ʻoi aku ka nui o ka overdose. I ka hapa nui, he kūpono kēia no ka hoʻohana pono ʻana i ka lāʻau lapaʻau.

Hiki i kahi overdose ke hoʻomohala i kahi ʻano patological e like me ka lactic acidosis. ʻO nā mea hōʻike nui loa: ka ʻeha o ka naʻau, ka luaʻi, ka lua, ke ʻike ʻole. Ke hele mai nei kēlā mau hōʻailona, e ʻae e kāpae i ka lawe ʻana i ka lāʻau.

Wahi a nā kauka e mālama maikaʻi ʻia ka lāʻau Gliformin me ka maʻi maʻi i nā maʻi maʻi, i ʻike ʻia e nānā pono ʻia nā mea i ʻōlelo ʻia. ʻO kekahi hoʻohui hou o ka lāʻau lapaʻau ke kumukūʻai kūpono a loaʻa i nā lāʻau lapaʻau.

Hoʻomaʻamaʻa ka poʻe Endocrinologists i loko o ka papa o ka hopena, pono nā hōʻike ʻōnaehana no ka bun serum. ʻAʻole pono e lawe pū ʻia ka lāʻau ʻo Glyformin no ka maʻi maʻi.

me nā mea inu ʻona,
nā mea kanu e loaʻa ai ka ethanol.

ʻO ka mea pōʻino, ua lilo ka maʻi diabetes i ka maʻi maʻamau, a i waena o nā poʻe'ōpio. No ka laʻana, pono ke kuhikuhi i kahi lāʻau lapaʻau e kōkua ana i ka hoʻololi ʻana i ke kiʻekiʻe o ka glycemia, kekahi o kēia mau lāʻau ʻo Gliformin. Inā hahai pono ʻia nā ʻōkuhi no ka hoʻohana ʻana, e hopena ka hopena o ka lāʻau i ka manawa pōkole.

Hāʻawi ʻia ka ʻikepili e pili ana i nā lāʻau lapaʻau haʻahaʻa i loko o ke wikiō ma kēia ʻatikala.

Nā kuleana a me nā kūlana e waiho ai

ʻO Gliformin kahi lāʻau lapaʻau lapaʻau.

Pono e mālama i kahi waiho maloʻo, hiki ʻole i ka komo ʻana o ka lā, i kahi wela a hiki i 25 ºº. Me ka mālama pono ʻana, ʻo ka ola o ka papa o nā papa 500 mg he 3 mau makahiki, 850 mg papa a me 1 grama - 2 mau makahiki.

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