Metfogamma 1000: nā kuhikuhi no ka hoʻohana ʻana, ke kumukūʻai, nā hui kālā gula
Metfogamma 1000 (mau papaʻaina) Rating: 8
Mea Hana: Vörwag Pharma GmbH & Co. KG (Kelemānia)
Kuhi puka:
- Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 176 mau rubles
Nā ʻōkuhi no ka hoʻohana
ʻO kekahi lāʻau lapaʻau no ka maʻi diabetes i ka hoʻokuʻu ʻana i ka papa maʻa. Kuhi i nā pahu pepa o 30 mau papa i loaʻa ka metformin hydrochloride ma ke ʻano he mea ikaika. Contraindicated i ka wā hāpai a me ka umauma.
Kūʻai a me ke kumu o ke hana o ka lāʻau lapaʻau
Ehia ka lāʻau? Aia ke kumu kūʻai i ka nui o ka metformin i ka lāʻau lapaʻau. No Metfogamma 1000 ke kumukūʻai ʻo 580-640 rubles. ʻO ka Metfogamma 500 mg mau kumukūʻai e pili ana i ka 380-450 mau rubles. Ma Metfogamma 850 ke hoʻomaka ke kumukūʻai mai 500 rubles. He mea kūpono ia e hōʻole ʻia nā lāʻau lapaʻau ma o ke kau lāʻau ʻana.
Hana lākou i ka lāʻau lapaʻau ma Kelemānia. Aia ka keʻena luna ʻelele ma Moscow. I nā makahiki 2000, ua hoʻokumu ʻia ka hana ʻana i ka lāʻau lapaʻau ma ke kūlanakauhale ʻo Sofia (Bulgaria).
He aha ke kumu o ke ʻano hana i pili ai i ka lāʻau? ʻO ka Metformin (ka hana ikaika o ka lāʻau lapaʻau) e hōʻemi i ke kao o ka glucose i ke koko. Loaʻa kēia i ka hana ʻana i ka gluconeogenesis i loko o ka puʻuwai. Hoʻomaikaʻi hoʻi ʻo Metformin i ka hoʻohana ʻana i nā glucose i loko o nā lau a hoʻemi i ka loaʻa ʻana o ke kō i loko o ka digestive tract.
ʻAʻole ia he mea kūpono inā ke hoʻohana ʻana i ka lāʻau lapaʻau, hoʻemi ʻia ka pae o ka cholesterol a me LDL i ka serum koko. Akā ʻaʻole hoʻololi i Metformin i ka nānāʻana o nā lipoproteins. I ka wā e hoʻohana ai i ka lāʻau lapaʻau, hiki iā ʻoe ke lilo i ka momona. ʻO ka maʻamau, ʻo kahi 500, 850, a me 100 met metogram e hoʻohana ai i ka wā ʻaina ʻole ke kōkua i ka hoʻēmi ʻana o ka paona.
ʻAʻole wale ka Metformin e hoʻohaʻahaʻa i ke kō o ke koko, akā hoʻomaikaʻi nui hoʻi i nā waiwai o fibrinolytic.
Loaʻa kēia i ka hoʻonāukiuki ʻana i kahi papa plasminogen a type-type.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
I nā hihia hea ka hoʻohana ʻana o ka lāʻau Metfogamma 500 i kūpono? ʻO nā ʻōlelo no ka hoʻohana ʻana e pono e hoʻohana i ka lāʻau lapaʻau i ka mālama ʻana i ka maʻi diabetes-2-type non-insulin. Akā ʻo Metfogamma 1000, 500 a me 800 mg e hoʻohana i ka mālama ʻana i nā maʻi i ʻike ʻole i ka ketoacidosis.
Pehea e lawe ai i ka lāʻau lapaʻau? Koho ʻia ka dosage e pili ana i ka pae o ka glucose i ke koko. ʻO ka maʻamau, ʻo ka dosis mua he 500-850 mg. Inā hoʻohana ʻia ka lāʻau lapaʻau e mālama i nā kiʻekiʻe o ke kō, a laila hoʻonui ka lāʻau i kēlā me kēia lā i 850-1700 mg.
Pono ʻoe e lawe i ka lāʻau lapaʻau i 2 mau puʻupuʻu māhele. Pehea ka lōʻihi e lawe ai au i ka lāʻau lapaʻau? No ka Metfogamma 850, ʻaʻole i hoʻoponopono ke aʻo i ka lōʻihi o ke kau ʻana. Koho ʻia ka lōʻihi o ka mālama ʻana i kēlā me kēia mea i hilinaʻi.
I Metfogamma 1000, nā ʻōlelo e hoʻohana ai i ka hoʻoponopono ʻana i kēlā mau contraindications no ka hoʻohana:
- Maʻi molaʻi.
- Nā maʻi āpau i ka hana o nā keiki.
- Haki puʻuwai.
- Ka pōʻino o Cerebrovascular.
- Ka maʻi waʻeha
- Naʻu?
- ʻO ke kumumānu o ke ahonui miʻi.
- Polōpiopio.
- He make alanā.
- Lactic acidosis
- Kahawai
- ʻO ka manawa lactation.
- Allergy i metformin a me nā mea kōkua o ka lāʻau.
Hōʻike nā loiloi o nā kauka ʻaʻole pono e hoʻohana i ka lāʻau i ka wā o kahi meaʻai haʻahaʻa, kahi i loaʻa ai ka liʻiliʻi ma mua o 1000 mau calorie i kēlā me kēia lā. Ināʻole, hiki i ka lāʻau Metfogamma 1000 ke hōʻeha i kahi hōʻeha koʻikoʻi, a hiki i kahi coma maʻi maʻi.
Hoʻomaʻamaʻa maikaʻi ʻia ka lāʻau lapaʻau e nā maʻi. Akā me ka hoʻohana mau ʻana o ka lāʻau lapaʻau, ka hopena o nā hopena like e like me:
- Megaloblastic anemia.
- ʻO nā hanaʻinoʻole i ka hana o ka papa kūloko. Hiki ke Metfogamma 1000 ke kumu i ka ulu ʻana o nā hōʻailona dyspeptic, nausea, ka luaʻi a me nā maʻi o ka maʻi. I ka wā hoʻi o ka lapaʻau ʻana, hiki i ka mea metallic ke kū mai i loko o ka waha.
- Hypoglycemia.
- Lactic acidosis.
- Allergic hopena pili.
Ke hōʻike nei ka hoʻomohalaʻana i ka lactic acidosis e ʻoi aku ka maikaʻi o ka hoʻopiʻi ʻana i ke ʻano o ka mālama ʻana.
Inā hele kēia kuhi, pono e lawe koke i ka lāʻau hōʻailona.
Nā Hoʻopuka i nā Laau a me nā Kauka Nona
Pehea ka launa ʻana o ka metfogamma 1000 me nā lāʻau lapaʻau ʻē aʻe? ʻŌlelo nā ʻōlelo i hiki i ka lāʻau lapaʻau ke hōʻemi i ka pono o ka mālama ʻana me ka hoʻohana ʻana i nā anticoagulants.
ʻAʻole ia e hoʻohana i ka lāʻau lapaʻau no ka maʻi maʻi me ka MAO inhibitors, ka ACE inhibitors, clofibrate derivatives, cyclophosphamides a beta-blockers. Me ka hoʻohui o metformin me nā lāʻau lapaʻi i luna, e hoʻonui ʻia ka loaʻa o ka hana hypoglycemic hoʻonui.
He aha nā huaʻōlelo maikaʻi loa o Metfogamma 1000? Wahi a nā kauka, ʻo ka koho maikaʻi loa e:
- Kūkulu (220-400 rubles). ʻO kēia lāʻau lapaʻau e like me ka Metfogamma. ʻO ka hana ikaika a ka lāʻau lapaʻau ka metformin. Ke kōkua nei ka lāʻau lapaʻau i ka hoʻohaʻahaʻa o ke koko a hoʻonui i ka ʻike ʻana o nā receptor insulin peripheral.
- ʻO Glibomet (320-480 mau rubles). Mālama ka lāʻau i ka lipolysis i ka kiko adipose, hoʻoulu i ka naʻau o ka peripheral kūloko i nā hana o ka insulin a hōʻemi i ke kō koko.
- Siofor (380-500 rubles). Mālama i ka lāʻau lapaʻau i ke kao ʻana o ka glucose i loko o ka ʻōpū, hoʻomaikaʻi i ka hoʻohana ʻana o ke kō i ke kōpū ma nā o nā mākio a hoʻopau i ka hana o ka glucose i loko o ka ate.
Noi ʻia nā lāʻau ma luna no ka hoʻohana ʻana me ka maʻi diabetes-2-type type 2. Ke koho nei i kahi analogue, pono ʻoe e kamaʻilio i kāu kauka, no ka mea hiki i nā lāʻau hōʻemi e hōʻemi i ka glucose ka mea e hoʻoulu ai i ka acidact lactic. Ke hoʻomau nei ke wikiō ma kēia ʻatikala i ke kumumanaʻo o ka hoʻohana ʻana i ka Metformin no ka maʻi diabetes.
Nā inoa o ka lāʻau Metfogamma 1000
ʻOi like ka analogue mai ka 66 mau rubles.
Mea Hana: Merck Sante SAA.S. (Palani)
Kuhi puka:
- Nā papa 500 mg, 30 pcs., Kumukūʻai mai 110 mau rubles
- Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles
Nā ʻōkuhi no ka hoʻohana
ʻO ka lāʻau Farani no ka mālamaʻana i nā maʻi maʻi 2. Kuhi i nā papa i loaʻa mai 500 a 1000 mg o ka metformin ka mea hana hoʻokahi. Aia kekahi mau contraindications, no laila, ma mua o ka lawe ʻana i Glucofage, pono e kūkā me kahi loea.
ʻOi like ka analogue mai ka 67 rubles.
Mea Hana: Akrikhin (Lūkia)
Kuhi puka:
- Nā papa 500 mg, 60 pcs., Kumukūʻai mai 109 rubles
- Nā papa 850 mg, 60 pcs., Kumukūʻai mai 190 mau rubles
Nā ʻōkuhi no ka hoʻohana
ʻO ka Gliformin kahi lāʻau mālama hale no ka mālama ʻana i nā maʻi maʻi 2. Kuhi ʻia i ke ʻano o nā papa me metformin ma ke ʻano he hoʻokahi mea hana (ʻo ke ʻano he 250 a 500 mg paha hiki). He papa inoa nui o Gliformin no laila, no laila ma mua o ka hoʻomaka ʻana i ka mālama ʻana, e noʻonoʻo e heluhelu i nā ʻōnaehana maʻamau no ka hoʻohana.
ʻOi aku ka palena o ka analogue mai ka 119 rubles.
Mea Hana: Lankana Leksredstva (Rūsia)
Kuhi puka:
- ʻLelo. 50 mg, 30 pcs., Kumukūʻai mai 57 mau rubles
- ʻLelo. 50 mg, 60 pcs., Kumukūʻai mai 99 rubles
Nā ʻōkuhi no ka hoʻohana
ʻO ka formmetin he kahakaha hou ke kumukūʻai no Glucofage, i hoʻolālā ʻia e hoʻohaʻahaʻa i ka glucose koko. Loaʻa i nā papa i loaʻa ka 0.5, 0.85 a i ʻole 1 g o ka metformin. Hiki iā ia ke hōʻeha i ka ʻōnaehana ʻana o ka ʻōnaehana, rashes, a me ka hihia o kahi overdose - hypoglycemia a me ka lactic acidosis me kahi hopena o ka mea.
ʻOi aku ka uku ma mua o nā aniani mai ka 2 mau rubles.
Mea Hana: Hemofarm A.D. (Serbia)
Kuhi puka:
- ʻLelo. 500 mg, 60 pcs., Kumukūʻai mai 178 mau rubles
- ʻLelo. 50 mg, 60 pcs., Kumukūʻai mai 99 rubles
Nā ʻōkuhi no ka hoʻohana
ʻO ka Metformin kahi lāʻau lapaʻau hypoglycemic Serbian no ka hoʻohana kūloko. ʻO ka hoʻonohonohoʻana o nā papa i loko o ka waihona hana ikaika o ka inoa like i loko o kahi waihona o 500 a 850 mg paha. Ua kuhikuhi ʻia no ka mālama ʻana i ka maʻi maʻamau ʻo 2 (i nā pākeke), ʻo ia hoʻi i nā maʻi me ka hiʻona.
Ua ʻoi aku ka uku o ka analogue mai ka 209 mau rubles.
Mea Hana: Kimika Montpellier S.A. (ʻAmelika)
Kuhi puka:
- Nā Papa 1000 mg, 60 pcs., Kumukūʻai mai 385 mau rubles
- ʻLelo. 50 mg, 60 pcs., Kumukūʻai mai 99 rubles
Nā ʻōkuhi no ka hoʻohana
ʻO ka lāʻau papa lāʻau Argentinean no ka mālamaʻana i ka maʻi maʻi. Hoʻokumu ʻia ka hana Bagomet me ka hoʻohana ʻana i ka metformin hydrochloride ma kahi o 500 mg no kēlā me kēia papa. Ua kuhikuhi ia no nā maʻi maʻi type 2.
Nā kuʻuna i ka hoʻonohonoho ʻana a me nā hōʻike no ka hoʻohana
| Ke poʻo inoa | He kumukūʻai ma Rusia | Kumukūʻai ma Ukraine |
|---|---|---|
| Bagometua Metformin | -- | 30 UAH |
| He metformin Glucofage | 12 ʻōpala | 15 UAH |
| Huʻi ʻia ka metformin xr | -- | 50 UAH |
| ʻO Reduxin Met Metinin, ʻo Sibutramine | 20 ʻōpala | -- |
| Dianormet | -- | 19 UAH |
| Metformin Diaformin | -- | 5 UAH |
| ʻO ke metformin metformin | 13 ʻōpala | 12 UAH |
| Metformin metozin metformin | -- | 13 UAH |
| Siofor | 208 ʻōpala | 27 UAH |
| ʻO ka metformin hydrochloride | -- | -- |
| ʻO Emnorm EP Metformin | -- | -- |
| Megifort Metformin | -- | 15 UAH |
| Metamine Metformin | -- | 20 UAH |
| Metamine SR Metformin | -- | 20 UAH |
| ʻO Tefor metformin | -- | -- |
| Glycometer | -- | -- |
| Glycomet SR | -- | -- |
| Kālaiʻa | 37 ʻōpala | -- |
| Metformin Canon metformin, ovidone K 90, mauʻa palaoa, crospovidone, magnesium stearate, talc | 26 ʻōpala | -- |
| Insuffor metformin hydrochloride | -- | 25 UAH |
| Metformin-teva metformin | 43 ʻōpala | 22 UAH |
| Diaformin SR metformin | -- | 18 UAH |
| Mepharmil Metformin | -- | 13 UAH |
| Metformin Metformin | -- | -- |
ʻO ka papa inoa ma luna o nā mea hoʻohālikelike lapaʻau, e hōʻike ana nā mea nona nā metfogamma, kūpono loa ia no ka mea ua like lākou me ka like o nā mea hana a me ke kūleʻa e like me ke kuhikuhi ʻana no ka hoʻohana
Ka ʻokoʻa like, hiki ke pili pū i ka hōʻike a me ke ʻano o ka noi
| Ke poʻo inoa | He kumukūʻai ma Rusia | Kumukūʻai ma Ukraine |
|---|---|---|
| Avantomed rosiglitazone, metformin hydrochloride | -- | -- |
| ʻO Glibenclamide Glibenclamide | 30 ʻōpala | 7 UAH |
| Maninyl Glibenclamide | 54 ʻōpala | 37 UAH |
| ʻO ka Glibenclamide-Health Glibenclamide | -- | 12 UAH |
| Glyurenorm glycidone | 94 ʻōpala | 43 UAH |
| ʻO Bisogamma Glyclazide | 91 ʻōpala | 182 UAH |
| ʻO Glidiab Glyclazide | 100 rub | 170 UAH |
| Diabeton MR | -- | 92 UAH |
| Diagnizide mr Gliclazide | -- | 15 UAH |
| ʻO Glidia MV Gliclazide | -- | -- |
| ʻO Glykinorm Gliclazide | -- | -- |
| Hoʻolaha ʻia Gliclazide | 231 rub | 44 UAH |
| Glyclazide 30 MV-Indar Glyclazide | -- | -- |
| Hoʻolaha-Hoʻolima Glyclazide-Health | -- | 36 UAH |
| ʻO Glioral Glyclazide | -- | -- |
| Hoʻolaha Glaclazide Diagnizide | -- | 14 UAH |
| Diazide MV Gliclazide | -- | 46 UAH |
| Osliklid Gliclazide | -- | 68 UAH |
| Gliclazide Diadeon | -- | -- |
| ʻO Glyclazide MV Gliclazide | 4 ʻōpala | -- |
| Amaril | 27 ʻōpala | 4 UAH |
| Glimepiride ʻO Glemaz | -- | -- |
| Hoʻolaha ʻia ka inoa momona | -- | 77 UAH |
| ʻO Glimepiride Glyride | -- | 149 UAH |
| Diapiride Glimepiride | -- | 23 UAH |
| Alarahi | -- | 12 UAH |
| Hoʻolālā ʻia ʻo Glimax | -- | 35 UAH |
| Gimepiride-Lugal glimepiride | -- | 69 UAH |
| Clay glimepiride | -- | 66 UAH |
| Glabepiride diabrex | -- | 142 UAH |
| Nā glimepiride ʻo Meglimide | -- | -- |
| Melpamide Glimepiride | -- | 84 UAH |
| ʻO ka glimepiride Perinel | -- | -- |
| Hoʻohui | -- | -- |
| Kahiʻu | -- | -- |
| Gimepiride glimepiride | 27 ʻōpala | 42 UAH |
| ʻO Glimepiride-teva glimepiride | -- | 57 UAH |
| Gimepiride Canon glimepiride | 50 ʻōpala | -- |
| ʻO Glimepiride Pharmstandard glimepiride | -- | -- |
| Dimaril glimepiride | -- | 21 UAH |
| ʻO Glamepiride diamerid | 2 hoʻoheʻe | -- |
| Amaryl M Limepiride Maikaʻi ʻia, Metformin Hydrochloride | 856 ʻōpala | 40 UAH |
| ʻO ka glibenclamide glibomet, metformin | 257 ʻōpala | 101 UAH |
| ʻO Glucovans glibenclamide, metformin | 34 ʻōpala | 8 UAH |
| Dianorm-m Glyclazide, Metformin | -- | 115 UAH |
| Dibizid-m glipizide, metformin | -- | 30 UAH |
| Douglimax glimepiride, metformin | -- | 44 UAH |
| Duotrol glibenclamide, metformin | -- | -- |
| Hoʻolauleʻa | 45 kahi | -- |
| Glibofor metformin hydrochloride, glibenclamide | -- | 16 UAH |
| Avandamet | -- | -- |
| Avandaglim | -- | -- |
| ʻO metumin metumin, sitagliptin | 9 ʻōpala | 1 UAH |
| Velmetia metformin, sitagliptin | 6026 rub | -- |
| Galvus Met vildagliptin, metformin | 259 ʻōpala | 1195 UAH |
| ʻO glimepiride Tripride, metformin, pioglitazone | -- | 83 UAH |
| Huihui XR metformin, saxagliptin | -- | 424 UAH |
| Metformin Comboglyz Prolong, saxagliptin | 130 ʻōpala | -- |
| Gentadueto linagliptin, metformin | -- | -- |
| ʻO ka metformin Vipdomet, alogliptin | 55 ʻ .pū | 1750 UAH |
| Sinjardi empagliflozin, metformin hydrochloride | 240 ʻōpala | -- |
| ʻO Voglibose Oxide | -- | 21 UAH |
| He pioglitazone Glutazone | -- | 66 UAH |
| ʻO Dropia Sanovel pioglitazone | -- | -- |
| ʻO Jasonvia sitagliptin | 1369 ʻōpala | 277 UAH |
| Galvus vildagliptin | 245 ʻōpala | 895 UAH |
| Onglisa saxagliptin | 1472 ʻōpala | 48 UAH |
| Nesina alogliptin | -- | -- |
| Vipidia alogliptin | 350 ʻōpala | 1250 UAH |
| Trazhenta linagliptin | 89 ʻōpala | 1434 UAH |
| Lixumia lixisenatide | -- | 2498 UAH |
| Noho ʻo Guarem Guarem | 9950 ʻōpala | 24 UAH |
| Hoʻopau ka Insvada | -- | -- |
| Novonorm Repaglinide | 30 ʻōpala | 90 UAH |
| Hoʻokomo ʻo Repodiab Repaglinide | -- | -- |
| Baeta Exenatide | 150 ʻōpala | 4600 UAH |
| Baeta Long Exenatide | 10248 ʻōpala | -- |
| Viktoza liraglutide | 8823 kahaki | 2900 UAH |
| Saxenda liraglutide | 1374 ʻōpala | 13773 UAH |
| Forksiga Dapagliflozin | -- | 18 UAH |
| Forsiga Dapagliflozin | 12 ʻōpala | 3200 UAH |
| Invocana canagliflozin | 13 ʻōpala | 3200 UAH |
| Jardins Empagliflozin | 222 ʻōpala | 566 UAH |
| Trulicity Dulaglutide | 115 ʻōpala | -- |
Pehea e ʻike ai i kahi analogue ʻano maʻalahi o kahi lāʻau lapaʻau nui?
No ka ʻike ʻana i kahi analogue kūʻai like ʻole i ka lāʻau lapaʻau, kahi generic a i ʻole synonymation, ʻo ka mea mua mua mākou i manaʻo no ka hoʻolohe ʻana i ka hoʻopili ʻana, ʻo ia nā ʻano like ʻole o nā mea kaha a me nā hōʻailona no ka hoʻohana. Hōʻike ka mea like ʻole o ka lāʻau lapaʻau me ka lapaʻau a like pū me ka lāʻau lapaʻau, kūloko a me ka mea pono i ʻole nā lāʻau lapaʻau. Eia naʻe, mai poina e pili ana i nā māhele like ʻole o nā lāʻau like like, e hiki ai ke hoʻopilikia i ka palekana a me ka hana. Mai poina e pili ana i nā kauoha a nā kauka, hiki i ka lāʻau lapaʻau ponoʻī ke hōʻeha i kou olakino, no laila e ʻōlelo mau i kāu kauka ma mua o ka hoʻohana ʻana i kekahi lāʻau lapaʻau.
ʻŌlelo aʻo Metfogamma
METFOGAMMA® (METFOGAMMA) hui Mohoʻāina: WERVAG FARMA GmbH a me Co.KG 10 mau pcs. - ʻōmole (12) - nā kāʻei o ke kāleka.
ʻO nā kolamu, keʻokeʻo kāwele ʻia, ʻoniʻoni, me kahi laina o ka paū.
1 kōpō metformin hydrochloride 850 mg
Nā mea kūlike: methylhydroxypropyl cellulose, povidone, magnesium stearate, titanium dioxide (E171), macrogol 6000.
10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa. 10 kamepiula - nā kīpaha blister (12) - nā ʻeke o ka pahu paʻi.
KAʻI KAHoli №№:
- pakuhi. hohola kiʻi, 850 mg: 30 a 120 paha nā pcs. - P No. 013816 / 01-2002, 03/12/02
- pakuhi. hohola kiʻi, 500 mg: 30 a 120 mau ʻōpena. - P No. 014463 / 01-2002, 10.16.02
ʻO ka lāʻau hypoglycemic Oral mai ka hui biguanide. Hoʻopiʻi ia i ka glucoseoneogenesis i loko o ka puʻuwai, e hoʻoneʻe i ka kao ʻana o ka glucose mai ka ʻōpū, hoʻomaikaʻi i ka hoʻohana ʻana i peripheral glucose, a hoʻonui hoʻi i ka ʻike ʻana o nā io i ka insulin. ʻAʻole pili i ka huna ʻana o ka insulin e nā β-cells o ka pancreas.
ʻO nā triglycerides haʻahaʻa, LDL.
Mālama a hoʻoikaika paha i ke kaumaha o ke kino.
Loaʻa ia he hopena fibrinolytic ma muli o ke kaohi ʻana o kahi kaila plasminogen activator inhibitor.
Ma hope o ka hoʻopale ʻana i ka waha, hoʻohuihui ʻia ka metformin mai ka digestive tract. Bioavailability ma hope o ka lawe ʻana i kahi maʻa maʻamau he 50-60%. Cmax ma hope o ka hoʻokō waha ʻana ma hope o 2 mau hola.
ʻAʻole hiki ke hoʻopaʻaʻia i nā protein plasma. Hoʻopili ia i nā kuhi salivary, nā mākala, nā puʻuwai, a me nā pūpū.
Hoʻokuʻu ʻia ia i hoʻololi ʻia ma ka urine. T1 / 2 ʻo 1.5-4.5 hola.
ʻO ka pharmacokinetics i nā hihia lapaʻau kūikawā
Me ka hana pūnāwai paʻa ʻole, hiki i ka hōʻiliʻili o ka lāʻau.
- ke ʻano type 2 diabetes mellitus (non-insulin-dependant) me ke kaʻa ʻole o ka ketoacidosis (ʻoi aku hoʻi i nā maʻi me ka obesity) me ka mālama ʻana i ka ʻai.
DOSAGE KA ʻElelo
E hoʻonohonoho i kēlā me kēia, ke nānā nei i ke kiʻekiʻe o ka glucose i ke koko.
ʻO ka ma mua mau lā ma mua o 0.5-1 g (Metfogamma 500) a i ʻole 850 mg (Metfogamma 850). Hiki ke hoʻonui hou i ka neʻe ma ka hopena o ka hopena. Hana ka kahu mālama i kēlā me kēia lā i ka nui o g g (Metfogamma 500) a i 0.85-1.7 g (Metfogamma 850). ʻO ka nui loa o ka lā i kēlā me kēia lā he 3 g (Metfogamma 500) a i ʻole 1.7 g (Metfogamma 850). ʻAʻole hoʻonui i ke kumu o ka lāʻau lapaʻau i nā kiʻekiʻe kiʻekiʻe o ka hopena.
Hoʻolako ʻia kahi wai lāʻau maʻamau ma mua o 850 mg i ʻelua mau wai (kakahiaka a me ke ahiahi).
I nā poʻe maʻi maʻi, ʻaʻole eʻoi aku ka nui o ka lāʻau i manaʻo ʻia ma mua o 850 mg / lā.
Pono e kiʻi ʻia nā papa me ka papa ʻaina holoʻokoʻa, e holoi ʻia me kahi liʻiliʻi o ka wai (kahi kīʻaha wai).
Kuhi ʻia ka lāʻau no ka hoʻohana ʻana i ka lōʻihi.
KA MANA NUI
Mai ka pūnaehana ʻana: ka nausea, ka luaʻi, ka ʻōpū o ka ʻōpū, ka maʻi ʻeha, ka nele o kaʻai ʻana, ka nele ʻana o ka makemake, ka ʻono metallic i loko o ka waha (me ke ʻano he kānāwai, ʻaʻole i koi ʻia nā hōʻailona ʻana i ka lākou iho me ka ʻole e hoʻololi i ka nui o ka lāʻau). Hiki ke hōʻemi ʻia ke nānā a me ka paʻakikī o nā hopena ʻaoʻao me ka hoʻonui mālie i ka hopena o ka metformin.
Mai ka pūnaehana endocrine: hypoglycemia (i ka wa i hoʻohana ʻia ai i nā pilala i wai ʻole).
Mai ka ʻaoʻao o ka hana o ka metabolism: i nā hihia maʻamau - lactic acidosis (koi i ka hoʻokuʻu ʻana o ka mālama ʻana), me ka hoʻohana lōʻihi - ka hypovitaminosis B12 (malabsorption).
Mai ka ʻōnaehana hemopoietic: i kekahi mau hihia - megalemia megaloblastic.
Nā maʻi kūlou: hāpau ka ʻili.
Koho kAka HONOLAHA
- ka maʻi ketoacidosis maʻi, maʻi diabetes precoma, coma,
- Hōʻeha renal,
- ka puʻuwai a me ka hanu,
- ka wili o ka myocardial infarction,
- ka maʻi maʻamau
- ke aloha kūlohelohe a me nā kūlana ʻē aʻe i hiki i ke kōkua i ka hoʻomohala ʻana i ka waikena lactic,
- ka lactic acidosis a me ka mōʻaukala o ia mea,
- lactation (umauma),
- Hypersensitivity i ka lāʻau lapaʻau.
ʻŌpū a me ka lactation
Hoʻopilikia ka lāʻau lapaʻau no ka hoʻohana ʻana i ka wā hāpai a i ka wā lactation (ka umauma o ka maʻi).
Koho KAHIKOLA
ʻAʻole kuhikuhi ʻia ka hoʻohana ʻana i ka lāʻau no nā maʻi maʻi maʻi pāpaʻomaʻi, exacerbation o nā maʻiʻeha a me nā maʻi maʻi, nā hōʻeha, nā maʻi ʻoihana maʻi, ke hōʻike ʻia ka maʻi insulin.
ʻAʻole lawe ʻia ka lāʻau ma mua o ka hoʻomaʻamaʻa ʻana a i loko o 2 mau lā ma hope o ke hana ʻana.
ʻAʻole kōkua ʻia ka hoʻohana ʻana o ka Metfogamma no ka liʻiliʻi loa ma 2 mau lā ma mua a me 2 mau lā ma hope o ka x-ray a i ka hoʻokolohua radiological e hoʻohana ana i nā kūlike.
ʻAʻole kuhikuhi ʻia ka hoʻohana ʻana i ka lāʻau lapaʻau no nā mea maʻi ma ka papaʻai me nā mea paʻa ma ka caloric intake (ma mua o 1000 kcal / lā).
ʻAʻole ia e noi i hoʻohana i ka lāʻau i loko o nā kānaka ma mua o 60 mau makahiki o ka mea e hana nei i ka hana kino kino (no ka mea pili kēia me ka nui o ka hopena o ka lactic acidosis).
I ka wā o ka hoʻohana ʻana i ka lāʻau, pono nā mākaʻikaʻi o nā hana hoʻohālike. Ma kahi o 2 mau manawa i ka makahiki, e like me ka nānā ʻana me myalgia, pono ka hoʻoholoʻana o ka lactate ma ka plasma.
Hiki ke hoʻohana ʻia ka metfogamma i ka hoʻohui me nā derivatives o sulfonylurea a i ʻole insulin, a pono e nānā pono ʻia ka nui o ka nui o ke kō o ka wai.
KAOLELO
Nā hōʻailona hōʻailona: e ulu paha nā momona lactic acidosis. ʻO ke kumu o ka hoʻomohala ʻana o ka acidosis lactic hiki ke lilo i ka hoʻohui ʻia o ka lāʻau ma muli o ka hana renal impaired. ʻO nā hōʻailona mua o ka lactic acidosis ka maʻi iki, ka luaʻi, ka maʻi ʻana, ka hoʻohaʻahaʻa i ke ʻano kino, ke ʻeha o ka naʻau, ka ʻeha o ka naʻau, ma ka wā e hiki mai ana ka nui o ka hanu, ka ʻōpū, ka hopohopo a me ka hoʻomohala ʻana i ka piko.
ʻO ka hoʻōla: inā loaʻa nā hōʻailona o ka acidosis lactic, mālama koke ʻia ka lāʻau me Metfogamma, pono e hoʻomāinoʻi ʻia ka mea maʻi a me ka hoʻoholo ʻana i ke ʻano o ka lactate, e hōʻoia i ka maʻi maʻi. He maikaʻi loa ka Hemodialysis e lawe i ka lactate a me ka metformin mai ke kino. Inā pono, e hana i ka therapy hōʻailona. Me ka hui pū ʻana me ka sulfonylureas, hiki i ka hypoglycemia ke ulu.
MOOLELO KAHAKAU
Me ka hoʻohana like ʻana me nā derivatives o sulfonylurea, acarbose, insulin, NSAIDs, MAO inhibitors, oxytetracycline, ACE inhibitors, clofibrate, cyclophosphamide, beta-blockers, hiki ke hoʻonui i ka hopena hypoglycemic o ka metformin.
Me ka hana like me ka GCS, ka maʻi wai hoʻohālike, ka epinephrine (adrenaline), sympathomimetics, glucagon, nā hormone thyroid, thiazide a me ka diuretics loopback, ka hopena derothinzine acid, ka mea hoʻemi i ka hopena hypoglycemic o ka metformin.
Hoʻololi ʻo Cimetidine i ke kāpae ʻana o ka metformin, e hoʻonui ai i ka hopena o ka lactic acidosis.
Hiki i ka metformin ke hoʻonāwaliwali i ka hopena o nā anticoagulants (dermaratives Coumarin).
Me ka hoʻokūkū pinepine me ka ethanol, hiki ke hoʻomohala ʻia ka hoʻomohala lactic acidosis.
