Dalacin C.

I kēiaʻatikala, hiki iā ʻoe ke heluhelu i nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau Dalacin. ^ E Ha yM. Hāʻawi i ka manaʻo o ka poʻe kipa i ka pūnaewele - nā mea kūʻai o kēia lāʻau lapaʻau, a me nā manaʻo o nā loea lapaʻau e pili ana i ka hoʻohana ʻana i kā antibiotika Dalacin i kā lākou hana. ʻO kahi noi nui, ʻo ia ke hoʻoikaika ikaika i kāu mau loiloi e pili ana i ka lāʻau lapaʻau: kōkua ka lāʻau lapaʻau a ʻaʻole hoʻi i kōkua i ka hoʻopiʻi ʻana i ka maʻi, nā mea hoʻopiʻi a me nā hopena ʻaoʻao, ua ʻike ʻia, ʻaʻole i hoʻolaha ʻia e ka mea hana ma ka annotation. Nā Dalacin analogues ma ke alo o nā mea hoʻokolohua kikoʻī i loaʻa. Hoʻohana no ka mālama ʻana i ka huehue (huehae), ʻokiʻoki, ʻokiʻoki a me nā maʻi ʻē aʻe i nā pākeke, nā keiki, ʻo ka wā ʻo ka wā hāpai a me ka lactation. ʻO ka hiʻohiʻona o ka lāʻau lapaʻau.

Dalacin - kahi antibiotic semisynthetic o ka linkosamide pūʻulu, i hoʻokumu ʻia mai lincomycin i ka hui ʻana o ka pūʻulu 7- (R) -hydroxyl e 7- (S) -chlor, hoʻoikaika i nā microorganisms gram-posit a me nā ʻano he nui o nā bacteria anaerobic. ʻO ka hapa nui o ka bacteria aerobic aolobic kino, e komo pū me Enterobacteriaceae, kūpaʻa i ka clindamycin.

ʻO Lincosamides, e like me macrolides (e.g., erythromycin), e hoʻopaʻa ai i ka 50S subunit o ka maʻi ribosome a me ka pale ʻana i ka synthesis o ka protein i nā wā mua. Ma muli o ke koʻikoʻi o ka microorganism a me ka paʻa o ka lāʻau, hiki i ka clindamycin ke hana bacteriostatically (ma mua loa) a i ʻole ka bactericidal (i nā hoʻokūkū kiʻekiʻe).

ʻO nā mea microorganisms e pili ana i ka clindamycin i ka vitro:

1. ʻO ka cocci positip Aerobic gram-positive, me ka: Staphylococcus aureus, Staphylococcus epidermidis (ʻo nā ʻōpala hana a ʻaʻole i hana i ka penicillinase). I hōʻike ʻia (i ka vitro) ka wikiwiki o ka hoʻomohala ʻana i ka pale i clindamycin ma kekahi staphylococcal erythromycin kūwili. Streptococcus spp. (koe wale nō ʻo Streptococcus faecalis), Pneumococcus spp.

2. Anaerobic gram-negative bacilli, me nā: Bacteroides spp. (komo pū me ka hui o B. fragilis, B. disiens, B. bivius and B. melaninogenicus), Fusobacterium spp.

3. Anaerobic gram-positive, non-spore form bacilli, me ka Propionibacterium spp., Eubacterium spp., Actinomyces spp.

4. Anaerobic a me microaerophilic gram-positive cocci, me ka Peptococcus spp., Peptostreptococcus spp., Microaerophilic Streptococcus spp., Clostridia spp .: clostridia e pale aku i ka clindamycin ma mua o nā mea ʻē aʻe. ʻO ka hapanui o Clostridium perfringens e pili i ka clindamycin, akā ʻo nā ʻano ʻē aʻe, e like me C. sporogenes a me C. tertium, kū pinepine i ke clindamycin, no laila, pono e hana ʻia nā hoʻāʻo ʻana.

5. Nā ʻōnaehana like ʻole, me ka Chlamydia trachomatis, Toxoplasma gondii, Plasmodium falciparum a me Pneumocystis carinii (i hui pū me ka primaquine), Gardnerella vaginalis, Mobiluncus mulieris, Mobiluncus curtisii, Mycoplasma hominis.

ʻO nā microorganism e like me ke kūpaʻa i ka clindamycin: aerobic gram-negative bacilli Streptococcus faecalis, Nocardia spp., Neisseria meningitidis, kūlia o ka methicillin-resistant Staphylococcus aureus a me nā māla o ka Haemophilus influenzae. Ke kū nei ka pale kūʻokoʻa ma waena o ka lincomycin a me clindamycin.

Hōʻike

ʻO Clindamycin + poʻe hoihoi.

Lapaʻau lāʻau

Ma hope o ka lawelawe waha, ua puka a wikiwiki a kokoke (90%) hoʻopili ʻana o ka dalacin. A lawe ʻia ma ka ʻōlelo maʻamau, ʻaʻole i hilinaʻi nui ʻia ka hoʻopili ʻana o ka clindamycin (quantitatively) i ka nui o ka pakanui ʻana o ka meaʻai, akā, ʻo ka hoʻāʻo ʻana me ka meaʻai e hoʻohaʻahaʻa i ka hoʻopili ʻana. Aia kahi pilina laina ma waena o ke kaʻe o ka clindamycin i ka serum a me ka make o nā lāʻau i lawe ʻia. ʻO 40-90% o ka lāʻau lapaʻau e lawelawe ai e hoʻopili i nā protein i ke kino. ʻAʻole komo ʻo Clindamycin i ke āpau-lolo lolo (BBB) ​​(a me ke kuʻi ʻana o ka meninges, nui ka mālamalama). Ma kahi ʻano hana i loli ʻole, e pili ana i ka 10% o ka lāʻau i ka mea i ʻoki ʻia mai ke kino e nā keiki, 3.6% - me nā feces. Hoʻopili ʻia ke koena ma ke ʻano he metabolites ʻole, ʻo ka hapanui me nā hua bile a me nā mea hao. ʻAʻole hoʻopili ʻia ʻo Clindamycin e hemodialysis a me nā dialysis peritoneal.

Nā Hōʻike

ʻO nā hōʻeha a me nā maʻi a ʻia e nā clindamycin-sensitive anaerobic bacteria a i ʻole nā ​​kaha o ka bacteria aerobic gram-maikaʻi, e like me Streptococcus spp., Staphylococcus spp. a me Pneumococcus spp., me ka clindamycin sensit Chlamydia trachomatis serovars:

• nā maʻi ʻeha hanu o ke aho, e komo tonsillitis, pharyngitis, sinusitis,
• ka waena o ka pepeiao pepeiao, ʻulaʻula,
• nā maʻi o ka ʻōpū hanu o lalo, ʻo ia hoʻi ʻO bronchitis, pneumonia, empyema o ka pleura a me ka pohihihi o ka māmā,
• nā maʻi ʻeha o ka ʻili a me nā ʻōpala palupalu, e komo nā huehue (huehae), furunculosis, kahi maʻi o ka momona momona subcutaneous, impetigo, abscesses, ʻeha nā maʻi, nā hanana hōʻehaʻeha ma nā ʻili a me nā kūlohelohe i hōʻāhewa ʻia e nā pathogens i kēia lāʻau lapaʻau, e like me ka erysipelas a me ka paronychia (panaritium).
• nā maʻi ʻeha o nā iwi a me nā hui, ʻo ia hoʻi osteomyelitis a me septic arthritis,
• Nā maʻi maʻi gynecological, ʻo ka endometritis, nā maʻi o ka momona subcutaneous, maʻi ʻana o nā io e hoʻopuni ana i ka pūpū, nā ʻōpala o nā ʻōpala fallopian a me ovaries, salpingitis a me nā maʻi maʻi o nā kuhi pelvic, i hui pū ʻia me kahi lāʻau antibacterial e ikaika ana i ka pathogens aerobic pathogens (e.g. gentamicin),
• ka hoʻonāukiuki o nā maʻi cervical ma o Chlamydia trachomatis,
• nā maʻi lēpa o ka ʻōpū o ka pūpū, me ka peritonitis a me nā ʻōpū o ka ʻōpū (i hui pū ʻia me nā lāʻau maʻi antibacterial e hana ana i nā huaʻai aerobic gram-hewa),
• septicemia a me ka endocarditis,
• nā maʻi pili o ka waha waha, e like me ka periodontal abscess a me ka periodontitis,
• toxoplasma encephalitis i nā maʻi maʻi AIDS (i hui pū me ka pyrimethamine i nā mea maʻi me ka hoʻomanawanui ʻole i ka hana maʻamau),
• ʻO ka maʻi polopiko pneumocystis i nā maʻi maʻi AIDS (i hui pū me ka primaquine i nā mea maʻi me ka hoʻomalala ʻole a kū ʻole i ke ʻano maʻamau)
• malaria, incl. i hoʻoulu ʻia e multiresistant Plasmodium falciparum, ma ke ʻano o ka monotherapy, a me ka hui pū me ka quinine a i ʻole chloroquine,
• ka pale ʻana o ka endocarditis i nā maʻi me ka hoʻonui nui ʻana i nā penicillins,
• mea maʻi puki

E hoʻokuʻu i nā palapala

Nā Capsules 150 mg a me 300 mg (i kekahi manawa i kuhihewa ʻia nā papa).

Nā koho ʻana i ka vaginal 100 mg No. 3.

Gel no ka hoʻohana waho waho 1% (Dalacin T).

Hoʻokomo ʻaila 3% (i kekahi manawa i kapa ʻia a poni).

ʻO ka hopena no ka hoʻokele intravenous a me intramuscular (Dalacin Ts phosphate) (injections ma ampoules no ka maʻi).

Nā ʻōkuhi no ka hoʻohana a me ka regimen dosage

I mea e pale ʻole ai i nā hoʻopiʻi, hoʻopili ikaika e like me ka ʻōlelo a ke kauka.

Nā pākeke: 600-1800 mg / lā i nā lā ma 2, 3 a i ʻole 4 mau kīnā (ʻona like pā).

Ke keiki: 8-25 mg / kg kino kino / lā ma ke waha ma 3-4 mau pona (like pū me nā pele).

I mea e pale aku ai i ka huhū o ka esophagus, pono ke lawe ʻia nā kapaka me ka ipu piha o ka wai.

Inā ʻoi ʻia ka nui o ka lāʻau lapaʻau ma lalo o ka haʻahaʻa o ka clindamycin i loko o ka capsule a i ʻole nā ​​pōmona pilikia, pono ke kuhikuhi ʻia nā ʻano makua.

ʻO nā maʻi i manaʻo ʻia e beta-hemolytic streptococcus: i hōʻike ʻia nā ʻōhua ma luna, e hoʻomau ʻia ka mālama ʻana ma kahi o 10 mau lā.

Nā maʻi hōʻeha a me nā maʻi ʻelua o nā papa pelvic: 900 mg iv clindamycin i kēlā me kēia hola 8 + iv a ʻo nā antibiotic kūpono e kūleʻa ana i ka pathogens aerobic gram-hewa (no ka laʻana, he gentamicin ma kahi pālahalaha o 2.0 mg / kg a hahai ʻia e 1.5 mg / kg kēlā me kēia 8 mau hola no ka poʻe maʻi me ka hana maʻamau maʻamau), ma ka liʻiliʻi he 4 mau lā, a ma hope o ka hoʻomaikaʻi ʻana o ke ʻano o ka mea maʻi, no ka liʻiliʻi he 48 mau hola. A laila huli lākou i ka lawe ʻana i ka clindamycin i loko o ka 450-600 mg i kēlā me kēia 6 mau hola i kēlā me kēia lā. ʻO ke ala piha o ka hopena he 10-14 mau lā.

ʻO nā maʻi Chlamydia trachomatis o ka uteri cervix: 450-600 mg orally 4 mau manawa i ka lā i kēlā me kēia lā no 10-14 lā.

ʻO ka Toxoplasmosis encephalitis i nā maʻi maʻi o AIDS: i nā mea maʻi me ka hoʻomanawanui ʻole i ka hana maʻamau, e hoʻohana ʻia ana ʻo clindamycin e hui pū me ka pyrimethamine e like me ka papa hana i kēia manawa: 600-1200 mg orally i kēlā me kēia mau hola 6 no 2 mau pule, a laila 300-600 mg wahaheʻe i kēlā me kēia mau hola 6. -75 mg ma waena i kēlā me kēia lā. ʻO ka maʻamau, ʻo ka papa kau o ka lapaʻau he mau wiki 8. Ke hoʻohana nei i nā dosis kiʻekiʻe o ka pyrimethamine, pono ke kuhi o ka folinic i loko o kahi waihona o 10-20 mg / lā.

ʻO nā maʻi maʻi o ka pneumocystis i nā mea maʻi me ka maʻi AIDS: 300-450 mg wahaheʻe i kēlā me kēia 6 mau hola no ka 21 mau lā a me ka primaquine 15-30 mg ma mua o hoʻokahi lā no 21 lā.

Tonsillococcal Acute streptococcal / pharyngitis: 300 mg orally 2 mau manawa i ka lā no 10 lā.

Malaria: 10-20 mg / kg / lā ma ka makua no nā pākeke a me 10 mg / kg / lā no nā keiki i kēlā me kēia mau hola 12 i ke koina no nā lā he 7 no ka lā monotherapy, a i ʻole hui pū me quinine (12 mg / kg i kēlā me kēia mau hola 12) chloroquine (15-25 mg i kēlā me 24 mau hola) no 3-5 lā.

Ke kāohi ʻana o ka endocarditis i nā mea maʻi me ka hoʻonui nui ʻana i ka penicillins: 600 mg orally no nā pākeke a me 20 mg / kg no nā keiki 1 ka hola ma mua o ka hoʻomaʻemaʻe ʻana a i ʻole ka hana maʻi niho a i ʻole kekahi hana e pili ana i ka hopena o ka endocarditis.

Nā maʻi maʻi ʻelemakule: ʻaʻohe mea pono e hoʻololi i ka maʻi maʻamau me kahi maʻamau (no kahi makahiki i hāʻawi ʻia) ka ate a me ka hana ʻana o nā keiki.

I waho. Hoʻohui ʻia kahi ʻāpana o ke aniani i ka wahi e pili ana i ka ʻili maloʻo maʻemaʻe 2 mau manawa i ka lā. I mea e loaʻa ai nā hopena maikaʻi loa, e hoʻomau ʻia ka mālama ʻana no nā wiki he 6-8, a inā pono, hiki iā ʻoe ke hoʻomau i nā mahina 6 mau mahina.

Hoʻokomo ʻia kahi wai hoʻokahi (1 mea hoʻopihapiha piha (5 g o kaʻaila, ma kahi o 100 mg o clindamycin)) i loko o ka vagina, maikaʻi loa ma ka wā hiamoe, no 3 a 7 mau lā he mau lā aʻe.

Ma kahi pahu me 20 g mau kāleka he 3 mau mea noi palaki, a ma kahi pānaʻi me 40 g he 7 mau mea noiʻi i manaʻo ʻia no ka hoʻopuka pololei ʻana i ka ʻano i loko o ka pūpū.

Nā rula no ka hoʻohana ʻana i ka lāʻau lapaʻau

1. Hoʻokuʻu i ka pāpale o ka puna o kaʻaila. E ʻōwili i kahi mea noi uila i ka ʻāʻī o ka ʻāʻī o ka pahu.
2. Ke kūwili nei ʻoe i ka pahu mai ka ʻaoʻao i ka ʻaoʻao, e lūlū i ka ʻono i loko o ka mea noi. Ua piha ka mea noi i ka wā e hoʻokomo ʻia ai kona pūlea i ka ʻoki.
3. E wehe i ka mea noi mai ka pahu a me ka pale.
4. Ke moe nei ma kou kua, e huki i kou mau kuli i kou umauma.
5. Ke paʻa pono nei i ka mea noi, e hoʻokomo pono ʻia i loko o ka pūʻupuʻu e like me ka hohonu, me ka ʻole o nā mea nānā ʻole.
6. Weʻe mālie Ke kani nei i ka piston a pau, hoʻokomo i ka ʻono i loko o ka kaʻi.
7. E mālama pono i ka mea noi i ka pūpū a hoʻokuʻu mai.

Loaʻa ka hopena

• ʻeha ka ʻōpū
• paila, mamaila,
• nā ninia
• esophagitis
• ulia esophageal
• ʻitislelo poloka
• kūlohelohe,
• mikulopapular rash,
• urticaria
• huu
• ka nui loa o ka manawa nui
• erythema multiforme,
• mokuhula a me nā dericitis o nā vesiculo-bullous,
• ʻO ka mea hoʻonāʻona ʻole o ka epidermal,
• hopena anaphylactoid
• nā hihia o neutropenia (leukopenia) a me ka eosinophilia o ke ʻano i hele ʻia.
• vaginitis
• hoʻomohala ʻana o ka superinfection.

Nā Hoʻohui

• hypersensitivity e pili i ka clindamycin, lincomycin a i ʻole kekahi mea o ka lāʻau.

ʻŌpū a me ka lactation

Clindamycin e hele i ka plasenta. Ma hope o ka hoʻopuka ʻana i kekahi mau doses o ka lāʻau lapaʻau, ʻo ke kaohi ʻana i ke kaila amniotic ma kahi o 30% o ka kaʻe ʻana i ke koko o ka makuahine. Pono e hoʻohana ʻia ʻo Clindamycin i nā wahine hāpai inā he pono ʻole ka manaʻo kumu i ka makuahine ma mua o ka hopena o ka wahine hāpai. Loaʻa ka Clindamycin ma ka waiū umauma ma ka hoʻolilo ʻana o 0.7-3.8 μg / ml.

Inā pono, ʻo nā koho i ka wā lactation e ho'ōki i ka umauma.

Nā ʻōlelo kikoʻī

I ka hihia o nā maʻi cervical i hoʻokumu ʻia e Chlamydia trachomatis, ʻo ka clindamycin monotherapy e hoʻohana pono ana e hoʻōla pono ai.

ʻO nā ala o ka pseudomembranous colitis o nā ʻano paʻakikī e ʻike i ka hoʻoweliweli ʻana i ola e nānā ʻia me ka hoʻohana ʻana o nā mea āpau a pau i ka maʻi antibacterial, me Dalacin, no laila nā mea āpau o ka maʻiʻeha ma hope o ka lawe ʻana i nā lāʻau antibacterial, pono e noʻonoʻo pono i kēia maʻi. Hoʻokomo i nā lāʻau antiodacterial i ka flora o ka maʻi maʻamau, hiki ke loaʻa i ka hoʻonui nui o ka clostridia. Ua hōʻike ʻia ua lilo nā mea i lawe ʻia e ka Clostridium difficile i ke kumu nui o ka colitis e pili pū ana me ka hoʻomehana antibiotic. Hiki i ka colse Pseudomembranous ke hele pū a ʻelua i ke wā e lawe ai i ka clindamycin, a me nā 2-3 mau pule ma hope o ka hoʻokuʻu ʻana i ka hoʻōla, hōʻike ʻia ia e ka maʻi maʻi, leukocytosis, ka maʻi ʻeha, ʻeha o ka ʻōpū (i kekahi manawa e hoʻopili ʻia me ka maʻi fecal a me nā māhu). Ma hope o ka hōʻike ʻana i ka colitis pseudomembranous i hōʻike ʻia i nā maʻi kūlohelohe, hoʻōla a me ka hoʻohana ʻana o nā resins de ion-exchange (colestyramine, colestipol) e lawa i ke kūleʻa ʻana, i nā hihia o ka hōʻino ʻeha a me nā hihia koʻikoʻi, uku hoʻopaʻi no ka nalowale o nā wai, nā electrolytes a me ka protein, ke koho ʻana i ka lāʻau hoʻōla a maikaʻi i kūleʻa i nā Clostridium difficile, no ka laʻana vancomycin i loko o kahi manawa o 125-500 mg, a i ole bacitracin i loko o kahi waihona o 25 000 IU i loko o 4 mau manawa i ka lā no 7-10 lā, a i ʻole metronidazole 250-500 mg 3 mau lā i ka lā. Pono nā lāʻau e hōʻemi i ka gastrointestinal motility ʻaʻole i kuhikuhi pū ʻia i ka clindamycin.

Ke hoʻohana nei i nā ʻaina antibacterial āpau, me ka clindamycin, ka ulu nui ʻana o nā microorganisms insensitive i kēia lāʻau lapaʻau, ʻoiai he mau huehue like ʻole. Me ka hoʻomohala ʻana o ka superinfection, pono e hana ʻia nā mea kūpono kūpono ma ke kūlana kauka.

ʻAʻole pono ke ʻōmaʻomaʻo Clindamycin no ka mālama ʻana i ka meningitis, no ka mea, ke komo maikaʻi ʻole ʻia nei ma o ka hala o ke koko-lolo (BBB).

Ke koho ʻana i ka lāʻau lapaʻau i nā papa kiʻekiʻe, pono ia e hoʻomalu i ka ʻike ʻana o clindamycin i ka plasma. Inā mālama ʻia ka hoʻomaʻamaʻa ʻana i kekahi manawa lōʻihi, a laila pono e hana pinepine ʻia nā ʻie a me nā maʻi hana.

I nā mea maʻi me ka pīpī a me ka hana o ka maʻi, ʻaʻohe hewa o ka hoʻololi ʻana i ke ʻano o ka lāʻau, no ka mea ʻaʻole i hōʻiliʻili ʻo clindamycin i loko o ke kino inā lawe ʻia ka lāʻau ma ke ʻano me he 8 hola.

Hoʻohui nūhou

Ua hoʻonohonoho ʻia ma ka antagonism vitro ma waena o dalacin a me ka erythromycin i hōʻike ʻia. No ka mea he nui loa kēia maʻi antagonism, ʻaʻole pono kēia mau lāʻau i ka manawa like. Aia kahi hōʻike pili o ka pilina like me ka chloramphenicol.

Ua hoʻokūpaʻa ʻia e hōʻino e Dalacin i ka hoʻoili ʻana i ka neuromuscular a no laila, hiki i ka hoʻoikaika ʻana i ka hopena o nā mea hoʻomaha ʻē aʻe o ka hana peripheral, no laila, pono ka hoʻohana ʻana i ka lāʻau lapaʻau me ka mālama ʻana i nā poʻe maʻi e loaʻa ana i nā lāʻau lapaʻau o kēia pūʻulu.

ʻO ka hoʻohana like ʻana o nā analgesics opioid (narcotic), he hopena ia i ka hopena o ka ʻōpū o ka hanu, hiki ke hoʻomālamalama hou aku i ka manawa hanu hou a hiki i ka apnea.

ʻO ka hoʻokele maʻalahi ʻana me nā lāʻau antidiarrheal e hōʻemi ana i ka maʻi gastrointestinal e hoʻonui ai i ka hopena o ka colse pseudomembranous.

Hoʻopuka ʻo Aminoglycosides i ka molaki o ka hana antimicrobial o clindamycin.

Nā kūmole o ka lāʻau Dalacin

Hoʻololi nā kumu hoʻohālike o ka waiwai ikaika:

• Dalacin C phosphate,
• Zerkalin
• Klimitsin,
• Clindamycin,
• Klindatop,
• Klindafer
• Clindacin
• Kolosa,
• Klindovit.

Nā hōʻailona no ka hoʻohana ʻana

ʻO nā maʻi maʻi i lawe ʻia e nā microorganisms mahele: nā maʻi o nā kino ENT (e pili ana i ka tonsillitis, pharyngitis, sinusitis, otitis media), nā maʻi ʻeha o ka ʻōpū (bronchitis, pneumonia, ka huhū o ka pūpū, ka empyema pleural, fibrosing alveolitis), nā maʻi o nā iwi a me nā ʻōpū () osteomyelitis, septic arthritis), nā maʻi maʻemaʻe o ka ʻili a me nā palupalu maemae (me ka huehue, ka wīwī, phlegmon, impetigo, panaritium, nā hōʻeha maʻi, abscesses, erysipelas), sepsis (ka nui anaerobic), nā maʻi pelvic a me nā maʻi intraperitoneal ( komo meperitonitis, absents o nā ʻōpū o ka ʻōpū me ka hoʻohana pū ʻana i nā lāʻau lapaʻau kūʻē i ka mikrob aerobic aerobic microbes), nā maʻi gynecological (endometritis, adnexitis, colpitis, nā ona o nā puna fallopian a me nā ovaries, salpingitis, peritonitis pelv) abses), toxoplasma encephalitis, malaria (i kumu o Plasmodium falciparum), nā maʻi pneumonia (i kumu o Pneumocystis carinii), sepsis, endocarditis, chlamydia, ʻehaʻulaʻula, hoʻōhule.

Pākuʻi helu

Kapuai 150 mg, 300 mg

Hoʻokahi nō i lawe ʻia ma:

mea waiwai - clindamycin hydrochloride 177.515 mg a i ka 355.030 mg (e like me ka clindamycin 150 mg a 300 mg),

nā mea hoʻowalewale: magnesium stearate, starch mais, talc, lactose monohala,

Kiunia lula? titanium dioxide (E 171), gelatin.

ʻO nā kapula gelatin opaque gel me ka uhi a me ke kino keʻokeʻo, ka ʻāpana ʻeleʻele i paʻi ʻia i ka hōʻailona "Pfizer" a me ke code "Clin 150". ʻO nā mea o nā pulupapa ke keʻokeʻo keʻokeʻo (no kahi ala o 150 mg).

ʻO nā kapula gelatin opaque gel me ka uhi a me kahi kino keʻokeʻo, ka ʻāpana ʻeleʻele i paʻi ʻia i ka hōʻailona "Pfizer" a me ke code "Clin 300". ʻO nā kiko o nā kapsul he keʻokeʻo keʻokeʻo (no kahi laʻe o 300 mg).

ʻO nā waiwai Pharmacological

Lapaʻau lāʻau

Ma hope o ka lawelawe waha, clindamycin wikiwiki a kahakaha holoʻokoʻa (90% o ka nui i lawe ʻia).

Hoʻokomo ka ʻai ʻaʻai i ka ʻai i ka ʻai o ke kaila i loko o ke koko koko.

Nā kikowaena serum

I ka poʻe olakino olakino, ʻike ʻia ka pileleka o ka pīpī plasma e pili ana i ka 2-3 mg / L a nānā ʻia i hoʻokahi hola ma hope o ka mālama waha waha he 150 mg o clindamycin hydrochloride a 4-5 mau lā / L ma hope o ka lawelawe waha o 300 mg. A laila, hāʻule ka hoʻolapalapa o ka plasma, e waiho ana ma luna o 1 mg / L no kahi o 6 mau hola. Hoʻonui ka uʻi Plasma i nā laina e like me ka hoʻonui o ka maʻa i lawe ʻia. Hōʻike ʻia ka ʻike ʻana o ka serum ma lalo o nā mea maʻi me ka maʻi maʻi ma mua o nā maʻi maʻi maʻi. ʻO ka awelika hapalua hapalua o clindamycin mai serum he 2.5 mau hola.

Palapala ʻaila Plasma

ʻO ka pilina ʻana i ka protein plasma mai 80 a 94%.

Ka hūʻī i loko o nā ʻili a me nā ʻano o ke kino

Hoʻalahalaha nui ʻia ʻo Clindamycin i nā kikowaena kiʻekiʻe loa i nā puna extracellular a me intracellular a i nā kiko. Hoʻohālikelike ʻia ka hoʻokaʻawale ʻana i loko o ka wai o ka cerebrospinal.

Hoʻomili ka Clindamycin i ka pīpī.

Ma kahi o 10% o ka lāʻau lapaʻau ma ka hana ikaika neʻe i loko o ka pāʻai a me ka 3.6% e hoʻopiʻi ʻia i loko o nā feces. Hoʻokuʻu ʻia ke koena i ka mea he metabolites hema ʻole.

ʻAʻole i loli iki nā mea hoʻopiʻi clindamycin ma muli o ka hemodialysis a i kēlā me kēia dialysis peritoneal.

Lapaʻau lāʻau

Hoʻohana ka palena iki o ka mahele o ke ʻano liʻiliʻi o ka pale o ka pale (MIC) e hoʻokaʻawale i waena o nā mea kanu hiki i ka lāʻau, nā mea ola me ka hiki ke kikowaena, a me nā mea ola me nā mea hiki ʻole i nā mea kūlohelohe.

S ≤ 2 mg / L a me R> 2 mg / L.

He ʻano ʻē paha ka loaʻa ʻana o ka pale kū i kekahi mau ʻano i pili i ka ʻāina kikoʻī a i ʻole ke manawa, a makemake ʻia e loaʻa i ka ʻike i nā ʻano kūloko o ka laha o ka kūʻē ʻana, i ka mālama ʻana i nā maʻi ʻino. Hāʻawi wale kēia ʻikepili i kahi manaʻo kokoke i ka hiki o ka hiki ʻana o nā mea ola me kēia antibiotic.

ʻO ka cocci hoʻōla huaʻelima, me nā:

-Streptococcus ʻaʻole no ka hui ʻana i nā pūʻulu

He gram-kāmela maikaʻi ʻole, e pili pū me:

Kāpena ʻinoaerobicnā pepeke

-ʻAʻole hoʻokipagram maikaʻikumiakai

Hōʻike ka Clindamycin i ka hana i loko o vitro a i vivo kue Toxoplasma gondii.

* ʻO ka pale nui o ka pale kūlohelohe methicillin ma kahi o 30 i 50% no ka staphylococci āpau a nānā nui ʻia i kahi kahua hoʻomaha.

ʻLoe a me ke kākele

Hoʻohana ʻia ka lāʻau lapaʻau i loko, i mea e pale aku ai i ka huhū o ka esophagus, pono e holoi ʻia nā kapaka i piha i kahi wai piha (250 ml).

ʻO ka maʻa maʻamau o kēlā me kēia lā he 600-11800 mg / lā, i hoʻokaʻawale ʻia i 2, 3 a i ʻole 4 mau like. ʻO ka palena loa o kēlā me kēia lā he 2400 mg.

ʻO nā maʻi maʻi Pediatric

Nā kaha o ka 8-25 mg / kg i kēlā me kēia lā, i māhele ʻia i 3 a i ʻole he 4 mau haʻahaʻa.

Hoʻohana ʻia i nā keiki inā hiki iā lākou ke ale i ka pulapona holoʻokoʻa.

ʻO nā maʻi maʻi

ʻO nā haʻawina ʻo Pharmacokinetic ma hope o ka hoʻokele waha a intravenous o clindamycin ʻaʻole i hōʻike i nā mea koʻikoʻi koʻikoʻi ma waena o nā poʻe ʻōpio a me nā poʻe maʻi me ka hana o ka ate a me ka maʻi maʻamau (ke nānā ʻana i ka makahiki) hana hana. Ma kēia mea, ʻaʻole ʻia ka hoʻoponopono ʻana i nā minamina i nā poʻe maʻi ʻelemakule me ka hana o ka ate maʻamau a me ke ʻano maʻamau.

ʻO ka maʻi me ka hana renal impaired

I nā maʻi me ka maʻi papau, ʻaʻole pono ka hoʻoponopono ʻana i nā ʻaina o clindamycin.

ʻO nā mea maʻi me ka hana pūlima hemahema

I nā mea maʻi me ka maʻi hepatic, ʻaʻole pono nā koi o ka hoʻoponopono ʻana o clindamycin.

Nā pāʻālua no nā hōʻike kūikawā

Hoʻopilikia i nā maʻi Beta Hemolytic Streptococcus

ʻO nā ʻōlelo kikoʻī kāwili i ka dosis ma luna o nā pākeke a me nā keiki. Pono e hoʻomau i ka hoʻomehana no ka liʻiliʻi o 10 mau lā.

Ka hoʻomaʻamaʻa ʻana o nā tonsillitis streptococcal a pharyngitis paha

ʻO ka dosis i ʻōlelo ʻia he 300 mg ʻelua i kēlā me kēia lā no 10 mau lā.

Hoʻopukaʻi maʻi maʻi maʻi ʻana i nā maʻi pelvic

Pono ka hoʻomaka ʻana o ka lāʻau maʻi me ka hopena intravenous Dalacin C Phosphate (ma kahi pāʻālua 900 mg i kēlā me 8 mau hola i hui pū ʻia me kahi antibiotic intravenous me kahi kikoʻī kūpono o nā hana kūʻē e kūʻē i nā microorganism o ka grobile-hewa, no ka laʻana, me ka gentamorin ma kahi o 2,0 mg / kg, a ukali ʻia e ka make o 1.5 mg / kg i kēlā me kēia 8 mau hola i nā mea maʻi me ka hana maʻamau maʻamau. Pono ka hoʻokele o ka lāʻau lapaʻau e hoʻomau no ka liʻiliʻi o 4 mau lā a ma kahi o nā hola 48 ma hope o ka hoʻomaikaʻi ʻana o ke ʻano o ka mea maʻi.

A laila, hoʻomau ʻoe e lawe i Dalacin® ma ke ʻano ma kahi o 450-600 mg i kēlā me 6 mau hola o kēlā me kēia lā a hiki i ka hoʻopau ʻana o ke ʻano o ka mālama ʻana me ka lōʻihi o 10-14 lā.

Hoʻokomo a me nā maʻi pūpū

ʻO ka ʻōlelo i ʻōlelo ʻia he 7.5 mg / kg i kēlā me 6 hola.

Kāohi i ka endocarditis i nā mea maʻi me ka mālama penicillin

I nā maʻi maʻi ʻōpiopio, ʻo ka pona i manaʻo ʻia he 600 mg 1 hola ma mua o ke kaʻina hana; nā keiki: 20 mg / kg 1 hola ma mua o ke kaʻina hana.

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa ka Dalacin i loko o nā palapalaʻano:

• Gel no ka hoʻohana waho waho 1%: i ka aniani, ka aniani, ka aniani (30 g kēlā me kēia puʻupuʻu, 1 tube i loko o ka pūlima pahu)
• ʻO ka pahu ʻaila 2%: keʻokeʻo (20 a 40 paha i kēlā me kēia mea i loko o ka waiū o ka polyethylene a i ʻole alumini foil e hoʻopau me 3 a 7 mau mea noi (no laila, 1 kau i loko o ka pahu paʻi)
• Nā Kūpepa: gelatinous, paʻakikī, me ke kino a me ka uhi keʻokeʻo, i kapa ʻia ʻia ʻo "P&U 225" (150 mg i kēlā me kēia) a me ka "P&U 395" (300 mg pākahi), nā kikoʻī o nā pulupone he keʻokeʻo keʻokeʻo (8 a 10 mau pcs. 2 a 10 paha i loko o kahi pahu pahu)
• ʻO nā manaʻo ākea: ʻo kā torpedo-ʻano, kūpaʻa, me kahi pālahalaha, kokoke ke keʻokeʻo a ʻokoʻa paha (3 pcs. I loko o nā kaula o ka laminated i ʻole a i ʻole ka mea noiʻi, 1 kaula i loko o ka pūlima pepa).

Ka hoʻonohonoho ʻana o 1000 gel gel no ka hoʻohana waho:

• Mea waiwai koʻikoʻi: clindamycin (ma ke ʻano o ka phosphate) - 10 mg,
• ʻO nā mea kōkua: methyl paraben - 3 mg, allantoin - 2 mg, polyethylene glycol - 100 mg, propylene glycol - 50 mg, carbomer 934P - 7.5 mg, kahi hopena o 40% sodium hydroxide - i nā nui nui, ka wai maʻemaʻe - i nā nui kikoʻī a hiki i 1000 mg . ^ E Ha yM.

Ka hoʻonohonoho ʻana o 1000 mg vaginal cream:

• Mea waiwai koʻikoʻi: clindamycin (ma ke ʻano o ka phosphate) - 20 mg,
• ʻO nā mea kōkua: cetyl palmitate - 32.1 mg, stearic acid - 21.4 mg, polysorbate 60 - 50 mg, sorbitan monostearate - 20 mg, propylene glycol - 50 mg, benzyl alkohol - 10 mg, cetostearyl alkohol - 32.1 mg, mineral aila - 64,2 mg, ka wai maʻemaʻe - i nā nui.

Kūkulu 1 kāʻei:

• Mea waiwai koʻikoʻi: clindamycin (ma ke ʻano o ka hydrochloride) - 150 a 300 mg paha,
• ʻO nā mea kōkua: talc, lactose, starch corn, magnesium stearate, gelatin, titanium dioxide.

ʻĀpana 1 hoʻokau ʻia ʻōiwi:

• Mea waiwai koʻikoʻi: clindamycin (ma ke ʻano o ka phosphate) - 100 mg,
• ʻO nā mea kōkua: solid fat (Witepsol H-32, kahi hui o monoglycerides, diglycerides a me triglycerides) - e pili ana i 2400 mg.

Nā Hoʻohui

Hoʻopili ka Dalacin i mua o nā hypersensitivity i ka clindamycin, lincomycin a i nā mea kōkua o ka lāʻau.

ʻO ka lāʻau lapaʻau i loko o ke ʻano o nā kapsul e pono e lawe me ka akahele me ka poʻe maʻi me nā maʻi gastrointestinal (mōʻaukala), ʻoi aku me ka ulitisative colitis, myasthenia gravis (hiki i ka pale ʻana o ka neuromuscular transmission), hōʻeha o ka pilikia hōʻeha.

Hoʻohui, ua hoʻomaʻamaʻa ʻia ʻo Dalacin ma nā ʻano maʻi ʻē aʻe i loko o nā maʻi / kūlana i lalo iho nei:

• ʻO ka mōʻaukala o nā antibiotitis e pili ana i ka antibiotika,
• ʻAne makahiki: a hiki i 18 mau makahiki no ka ʻūhā vaginal a me nā manaʻo, a hiki i ka 12 mau makahiki no ka gel no ka hoʻohana ʻana i waho (ʻaʻohe data i ka pono a me ka palekana o Dalacin ma kēia pūʻulu o nā maʻi).
• ʻO ka maʻi o ka lincomycin a clindamycin paha i loko o kahi anamnesis (no ka gel no ka hoʻohana waho)

ʻLoe a me ke kākele

Lawe ʻia ka Dalacin i loko o ka capsule. I mea e pale ai i nā hoʻopiʻi, ʻoi aku ia e hoʻohana ikaika e like me ka ʻōlelo a ke kauka.

I mea e pale aku ai i ka huhū o ka membamous o ka esophagus, pono ke lawe ʻia i nā capsules me kahi kīʻaha piha piha o ka wai.

ʻO ka lāʻau lapaʻau e lawe pinepine ʻia:

• Nā pāʻelemakule: 600-1800 mg i kēlā me kēia lā, ka wā o ka hoʻokele - ʻo 2 mau manawa (i nā kaha like)
• Ke keiki: 8-25 mg / kg o ke kaupaona o ke kino i kēlā me kēia lā, ʻo ka nui o ka hoʻokele he 3-4 mau manawa (ma nā kaulike like).

I ka mālamaʻana i nā maʻi i kumu ʻia e ka beta-hemolytic streptococcus, hoʻohana ʻia ʻo Dalacin i nā inika i hōʻike ʻia i luna. ʻO ka lōʻihi loa o nā papa therapeutic ma kahi o 10 mau lā.

Hoʻomaka ka mālama ʻana i nā maʻi maʻi pāpaʻi a me nā maʻi maʻi o nā pelvic i ka hoʻokele intravenous o clindamycin, ma kahi kikoʻī o 900 mg kēlā me kēia 8 mau hola, i ka manawa like me kahi mākia antibacterial kūpono loa ma kahi o 4 mau lā. Ma hope o ka holomua o ke ʻano o ka mea maʻi, hoʻomau ka hoʻomau i ka lāʻau ma ka liʻiliʻi loa he 2 mau lā hou, ma hope o ke kuhikuhi ʻia ʻana o Dalacin i ka ʻano o nā capsules i loko o hoʻokahi kaila o ka 450-600 mg. Lawe ʻia ka lāʻau i kēlā me kēia lā i kēlā me kēia 6 mau hola. ʻO ke ala holoʻokoʻa o ka lā 10-14 lā.

Wahi a nā hōʻike hōʻike, kuhikuhi ʻia ʻo Dalacin:

• ʻO ka Toxoplasmosis encephalitis i nā maʻi maʻi o ka maʻi AIDS: ma ka hoʻomohala ʻole ʻana i ka hana maʻamau, lawe ʻia ka lāʻau i ka manawa like me ka pyrimethamine e like me ke kumuhana i lalo iho nei: Dalacin - 600-1200 mg i kēlā me 6 mau hola no 14 mau lā, a laila 300-600 mg me ka like o ka hoʻohana pinepine ʻana, pyrimethamine - i kēlā me kēia lā 25 -75 mg. Ma ke ʻano he kānāwai, ʻo ka papa hana o ka papa he 8-10 mau pule. Ke hoʻohana nei i ka pyrimethamine i nā koina kiʻekiʻe, 10-20 mg o ka waikawa folic i kēlā me kēia lā e kuhikuhi ai.
• ʻO nā maʻi hūnāʻana i hōʻeha ʻia e Chlamydia trachomatis: 450-600 mg i kēlā me kēia lā, dosage 4 manawa i ka lā, e mālama ʻia ana ka lā 10-14 lā,
• Acary streptococcal pharyngitis / tonsillitis: no nā lā 10, 300 mg 2 mau manawa i ka lā,
• ʻO nā maʻi maʻi o ka pneumocystis i nā maʻi maʻi AIDS: no nā lā 21, 300-450 mg i kēlā me 6 mau hola i ka manawa like me ka primaquine, 15-30 mg hoʻokahi manawa i ka lā.
• Malaria: ʻo nā pākeke - 10-20 mg / kg i kēlā lā, nā keiki - 10 mg / kg i kēlā me kēia lā. Lawe ʻia ka lāʻau ma nā koina i kēlā me kēia mau hola 12, ʻo 7 ka lōʻihi o ke kau. Hiki nō hoʻi ke hoʻohana i ka Dalacin i ka manawa like me ka quinine (ʻo kēlā me kēia mau hola 12 ma 12 mg / kg) a i ʻole chloroquine (kēlā me kēia 24 hola ma 15-25 mg), ʻo ka lōʻihi o ka papa no 3-5 lā.

No ka pale ʻana i ka endocarditis i nā maʻi me ka hypersensitivity i nā penicillins, ua kuhikuhi ʻia ʻo Dalacin: no nā pākeke - 600 mg, no nā keiki - 20 mg / kg. Pono ka lālani e hoʻokaʻawale i ka hola 1 ma mua o ke komo ʻana o ka ʻokiʻoki liʻiliʻi a i ʻole ma ke ʻano he mea hana ʻē aʻe paha e ola ana i ka hopena o ka endocarditis.

ʻO nā mea maʻi aʻelemakule me ka hana maʻamau a me ka hana hepatic no kahi makahiki i hāʻawi ʻia, a me nā poʻe maʻi me nā maʻi hana o ka pūpū a me nā pūpū, ʻaʻole pono e hoʻoponopono i ka ʻōpū.

I ka mālamaʻana i ka maʻi vaginosis, ʻōlelo pinepine ʻia:

• ʻO ka ʻaila ʻaʻa: 5000 mg o kaʻaila (1 ka mea hoʻopihapiha piha, ma kahi o 100 mg o clindamycin) e hoʻokomo i loko o ke kaʻi. Hana maikaʻi ʻia ke kaʻina hana ma mua o ka hiamoe ʻana. Ka wā papa - 3 a 7 paha lā,
• ʻO kahi koho hoʻonaninani: 1 mālama ʻia ke kākoʻo me ka manawa 1 ka manawa i kēlā me kēia lā, ʻoi aku ka maikaʻi ma mua o ka hiamoe. Noho ka papa i 3 mau lā.

ʻO Dalacin i ke ʻano o ka gel ka hoʻohana i waho ma ka mālama ʻana i kahi palaka vulgaris. Hoʻohana ʻia ka lāʻau lapaʻau i loko o kahi palupalu i ka wahi i hoʻopuni (kino, maʻemaʻe hoʻi ke kino) Hoʻohana ʻia - 2 mau manawa i ka lā. ʻO ka lōʻihi papa ʻōlelo makemake ʻia ʻo 6-8 mau pule. Wahi a nā hōʻike hōʻike, hiki ke hoʻohana ʻia ka hoʻohana ʻana o Dalacin i 6 mau mahina. Inā, ma hope o ka noi ʻana i ka gel no nā mau mahina, ke emi nei ka hopena o ka mālama ʻana, e pono ʻia kahi hoʻomaha no ka 4 hebedoma.

Nā hopena hopena

Ke hoʻohana nei i Dalacin i loko, hiki i nā hopena pili aʻe:

• Pūnaehana Digestive: nausea, ʻeha ʻeha, esophagitis, ʻōpū a me ka luaʻi, pseudomembranous colitis, ulia esophageal, jaundice, dysbiosis, ate hana ʻeha, me nā hyperbilirubinemia,
• Hematopoiesis (hematopoietic system): nā hihia o ka eosinophilia o ke ʻano lehelehe a me ka leukopenia (neutropenia), a me nā hihia o ka thrombocytopenia a me agranulocytosis, ua ʻike ʻia naʻe, ʻaʻohe mea pili i waena o ke kaʻi ʻana o Dalacin a me kēia mau mea i ʻike ʻia.
• Nā hopena alerine: pruritus, urticaria, maculopapular rash, ʻoi loa ka maʻamau o ka mea nui o ka manawa poʻo ke ʻano o ka hoʻohaʻahaʻa a me ka hōʻeha ʻāwili, ʻano liʻiliʻi - vesiculobulous and exfoliative dermatitis, toxic epidermal necrolysis, erythema multiforme, anaphylactoid reaksi,
• Nā huaʻehā: vaginitis.

I ka wā o ka papa maʻi, hiki i nā hopena ʻaoʻao hope loa: ke hoʻomohala ʻana o ka superinfection, hoʻokele i ka hoʻōla ʻia a neuromuscular.

Ke mālama nei i ka maʻi bacterial me Dalacin i loko o ke ʻano o ka vaginal cream a me nā suppositories, hiki ke kūkulu i nā maʻi hōʻino mai kekahi mau pūnaehana kino:

• Pūnaehana lahui: vulvovaginitis, vagias candidiasis, kahe ʻana o ka ʻōpū, hoʻonāukiuki ʻana i ka membous mucous o ka pūpū a me nā vulva, ʻeha pūpū, trichomonas vaginitis, ʻeha ʻōpū, ka hānau hewa, ka wā haehae, ka wā hoʻoneʻe, ka hopena endometriosis,
• Pūnaehana urinary: urinary tract infection, dysuria, proteinuria,
• Pūnaehana Digestive: ʻono hoʻowahāwahā, lemulewa, ʻōpū, ka ʻōpala, ka luaʻi, dyspepsia, constipation, halitosis, gastrointestinal ʻeha,
• ʻIli: erythema, itching, rash, candidiasis o ka ʻili, maculopapular rash, urticaria,
• Pūnaehana pīhoihoi waena: dizziness, headache, vertigo,
• Pūnaehana Endocrine: hyperthyroidism, glucosuria,
• Pūnaehana respiratory: ʻihi o ke aho hanu, luna paha,
• ʻO ke kino holoʻokoʻa: nā maʻi hāhiʻi, nā maʻi maʻi maʻi, ka hoʻolaʻa, nā ʻōpū a me / ʻeha hōʻeha ʻana i ka ʻōpū, hōʻeha o ka ʻōpū, ka ʻōpū o ka puʻuwai, ka haʻalele ʻana i nā hualoaʻa o nā loiloi ʻo ka microbiological mai ke kumu maʻamau, ʻeha hope, a me ke kūloko.
• Nā kūloko kūloko: edema maʻi a me ka hana ʻeha i ka wahi i ʻōlelo ʻia.

Ke noi nei i ka gel no ka hoʻohana waho, hiki i nā hopena hope loa:

• Pūnaehana Digestive: colitis, ʻeha ʻeha, pseudomembranous colitis, dyspeptic disorders (ʻāhaʻi, huʻi, huʻu),
• ʻO kaʻili o ka hihiʻo: ʻā ana i ka maka i ka maka,
• Nā huapalapala: ʻoi loa - ka ʻili maloʻo, hoʻonui i ka hana o nā kohu sebaceous, kūlohelohe o ka ʻili, urticaria, contact dermatitis,
• ʻO kekahi: folliculitis i kumu o ka flora gram-maikaʻi.

Nā ʻōlelo kikoʻī

Me ka hoʻomohala ʻana o ka maʻi maʻi ma hope o ka hoʻopili ʻana iā Dalacin a i ʻole a intravaginally, pono e noʻonoʻo i ka hiki ke hoʻomohala ʻana i ka colitis pseudomembranous. Hiki nō hoʻi i ka maʻi maʻi 2-3 mau pule ma hope o ka hoʻokuʻu ʻana o ka maʻi. ʻO kāna mau hiʻohiʻona nui ka: nā maʻi o ka maʻi, ka maʻi leukocytosis, ka maʻi, ka ʻeha o ka ʻōpū (i kekahi manawa e hele pū ʻia me ka ʻōlelo huna o ka ʻūhā a me ke koko me nā feces). Inā pono, pono e lawe ʻia ka lāʻau pākōlohi a me nā lāʻau lapaʻau.Me ka hoʻohana o waho o ka lāʻau lapaʻau, ʻaʻole iki nā hihia o ka colitis, akā naʻe, pono e mālama ʻia ka mālama a, inā he mau lōʻihi a he maʻi paha paha, e pono ai ke hoʻohana ʻia ka gel.

No nā maʻi cervical ma o Chlamydia trachomatis, he hoʻoponopono maikaʻi ke kapsul monote me Dalacin no ka ho'ōla piha ʻana.

Ke lawe nei i Dalacin i loko, ulu nui nā microorganisms insensitive i ka lāʻau lapaʻau, hiki iā ia, me nā pūnihi-like-ye like. I ka hihia o ka superinfection, ma muli o ke kūlana maʻi, pono nā hana kūpono e pono ai.

ʻAʻole kuhikuhi ʻia ʻo Clindamycin no ka mālama ʻana i ka meningitis.

I ke koho ʻana iā Dalacin i nā koina kiʻekiʻe, pono ʻoe e kaohi i ka ʻike ʻana o clindamycin i ka plasma. Me ka lōʻihi o ka hoʻopaʻa ʻana, pono e hoʻomaʻamaʻa i ka hana maʻamau a me ka hana naʻau.

Pono e hoʻokaʻawale ʻia nā pathogens hou ma mua o ke kuhikuhi ʻana iā Dalacin no ka mālama ʻana i ka vulvovaginitis: Chlamydia trachomatis, Trichomonas vaginalis, Candida albicans, Neisseria gonorrhoeae a me Herpes simplex virus.

Pono e hāpai i ka hoʻohana pono ʻana o ka lāʻau i ka ulu o ka microorganisms insensitive e hana i kāna hana, ʻoi aku nā pupu-like-rewena.

Me ka hoʻohana nui ʻana o ka lāʻau lapaʻau, pono e ʻalo ʻia ka hoʻopili ʻana, a me ka hoʻohana ʻana i nā ʻano huahana ʻē aʻe e lawelawe ʻia ana intravaginally (no ka laʻana, syringes, tampons).

ʻAʻole hoʻohana ʻia ka hoʻohana ʻana o Dalacin i kahi ʻano i kaʻaahi a i ʻole ka palaki i ka wā o ka haʻu ʻana. ʻO ka hoʻomaka ʻana o ka lāʻau i kēia hihia ke hoʻopanee ʻia a hiki i ka hopena o ke kāne.

Nā Dalacin i nā ʻāpana e hoʻopili ai i ka ikaika o nā hua lāʻau a i ʻole ka hopena i ka hopena (hānau hoʻomalu i ka hānau ʻana i nā waha o nā puʻuwai, condoms). ʻAʻole hoʻohana ʻia ka hoʻohana ʻana o ia mau huahana i ka wā o ka ʻoihana a i loko o 3 mau lā ma hope o ka hoʻohana ʻana i ka lāʻau.

Hōʻalo i ka hoʻopili ʻana me ka gel no ka hoʻohana waho ma nā membrane haole a me nā maka. Ma hope o ka hoʻopili ʻana i ka lāʻau lapaʻau, holoi holoi i kou mau lima. I ka ʻike kūkaʻi ʻana me nā wahi iʻike ʻia (mau ʻōpū ma luna o ka ʻili, nā maka, nā membrane mucous), e holoi ikaika me ka wai anuanu.

Hoʻohui nūhou

ʻAʻole pono e lawe Clindamycin i ʻōlelo maʻamau ma ka manawa like me ke erythromycin a me ka chloramphenicol.

Aia ka pale o ka hoʻōla ʻana o nā microorganisms i ka lincomycin a me clindamycin.

Pono e hoʻohana ʻia ʻo Clindamycin me ka mālama ʻana i nā maʻi i loaʻa i nā hoʻomaha hoʻomaha peripheral.

Me ka hoʻohana like ʻana o Dalacin i loko me ka opioid (narcotic) analgesics me kahi hopena pale i ka hopena o ka hana ʻana o ka hanu, ka hoʻomohala ʻana o kahi maʻi ʻōpū o ka hanu hou a hiki i ke apnea hiki.

Hoʻopilikia ka hopena hoʻomohala i ka colitis pseudomembranous me ka hoʻohana pū ʻana o Dalacin me nā lāʻau antidiarrheal e hōʻemi ana i ka motility gastrointestinal.

Hoʻopili ke antimicrobial spindy o clindamycin e aminoglycosides.

ʻAʻole hoʻolako ʻia ka hoʻohana pinepine ʻana o ka cream vaginal a me nā suppositories me nā lāʻau ʻē aʻe no ka hoʻokō intravaginal.

Nā inoa o Dalacin i: Klindatsin, Klindes, Klindamitsin, Klindovit, Klindatop.

Nā ʻ Dallelo Dalacin C

ʻO ke kumukūʻai o nā kapsul - mai 1324 p.

Aia nā kāpena i ka talc, lactose a me ka magnesium stearate e like me nā mea kōkua. Ua hoʻohana ka anga i ka huaʻai, titanium dioxide a me ka gelatin.

ʻO nā kapuwai mua. Hiki iā lākou ke pālahalaha 150 a 350 mg paha. Kākala ka kākoi, kakala o ke kino a ʻulaʻula a ʻōlelo keʻokeʻo paha ke kala o ka pau i loko ma keʻokeʻo.

Nā kūmole no ka ʻōlelo

ʻO ke kumukūʻai o Dalacin C i loko o kahi hopena o kahi hopena no ka hōʻemi ʻana mai ka 587 r no kēlā me ka ampoule.

I ka hopena no nā inikini, nā wai hou e lilo ai i ka wai no ka injection, disodium edetate, benzyl ka waiʻona.

ʻO nā Ampoule i loaʻa 2, 4 a i ʻole 6 ml mau hopena. ʻAno ʻulaʻula ʻole ka wai. Aia ia ma nā hakahaka i hana ʻia me ke aniani ʻāpana ʻole o ka papa I.

Hoʻohui a me nā ʻano ʻē aʻe

ʻO nā ʻōlelo no nā lāʻau lapaʻau e hiki ke hoʻopilikia i ka pharmacokinetics o nā lāʻau lapaʻau hou.

No laila, hiki iā ia ke hoʻoikaika nui i ka hopena o nā mea hoʻomaha otot ma ke kino. No laila, lawe pinepine ʻia ka hoʻohana ʻana o kēia mau lāʻau i lalo o ka mākaʻikaʻi koʻikoʻi o kahi kauka. Hoʻoponopono maoli ke ʻano o nā lāʻau ʻelua.

Inā ʻoe e hoʻohana i nā lāʻau anti-diarrhea a me nā lāʻau ʻo Dalacin C i ka manawa like, hoʻonui ka nui o ka colitis.

Hoʻoleʻo loa ia e hoʻohana i ka huahana, nā ʻōlelo aʻo e kūkākūkā ai ma ka ʻatikala, i hui pū me ka calcium gluconate, barbiturates, erythromycin, aminophylline, ampicillin, magnesium sulfate.

Nā hopena hopena

Ke lawe nei i ka lāʻau lapaʻau, nui nā hōʻailona maikaʻi ʻole hiki mai.

Hiki i ke mālama me kēia maʻi maʻi:

• ʻEha ka ʻōpū
• Puka a luwau
• Nā maʻi maʻi
• Esophagitis
• ʻO ka Dysbacteriosis
• ʻO Thrombocytopenia
• Leukopenia
• ʻO Agranulocytosis
• Eosinophilia
• ʻO ka Vaginitis
• Hoʻopau nā ʻili, nā kuʻi, a me ka ʻeha
• Nāwaliwali kino
• ʻʻAla
• ʻApau
• Ke koko kiʻekiʻe

Me ka hoʻohana mau ʻana i nā kapeta, e hoʻomohala paha nā ʻōpū esophageal.

I nā hihia liʻiliʻi, hiki i ka antibiotika ke hoʻonāukiuki i ka necrolysis epidermal toxic.

Hiki ke hōʻike ʻia kahi hopena kūlohelohe i ka lāʻau e like me ka pīhoihoi anaphylactic.

Hiki iā ʻoe ke aʻo hou e pili ana i ke pehea e hiki ai iā ʻoe ke hoʻopau i ka maʻi hōʻeha i ka ʻatikala: hakakā i ka maʻi maʻi.

Ke keu

ʻAʻole kākau ʻia nā hihia o ka overdose.

Eia nō naʻe, inā ʻaʻole ʻoe i hoʻopili i ka dosis, ʻoi ka nui o ka loaʻa ʻana o ka pīhoihoi anaphylactic. E hoʻopau iā ia, hoʻohana ʻia nā lāʻau antihistamines a me nā glucocorticoid, me ka adrenaline. ʻO ka hopena o ka hemodialysis i ka hopena o nā hopena anaphylactic ua ili. ʻAʻohe mea antidote kiko'ī i ka mea ikaika a Dalacin C.

Nā kuleana a me nā kūlana e waiho ai

ʻO ka ʻōlelo a ka lāʻau lapaʻau e ʻōlelo ana e pono ʻoe e hoʻokomo i kahi wahiʻeleʻele me ka humuhumu maʻamau. Hiki ke mālama i ka mālama ʻana mai 15 a 25 degrees Celsius.

ʻO ke ola o kahi pale i nā puka capsule he 60 mau malama.

ʻO ka lāʻau lapaʻau i ke ʻano o kahi hopena no ka injections hiki ke hoʻohana no 24 mau mahina mai ka lā o ka hana ʻana.

Akrikhin OJSC (RF) a i ʻole Pharmaprim LLC (Moldova)
Kūʻai - mai 207 r e

ʻO ka pahuhopu mea like like me ka lāʻau lapaʻau i nīnau ʻia. Loaʻa i ka ʻano o nā suppositor a vaginal a i ʻole kaʻaila.

NOHO

• ʻOi aku ka maikaʻi no ka vaginosis bacterial, me ka noi ʻia topically
• ʻO kaʻaila kahi pepa e kūpono e hoʻopili ai.

ʻĀpuka:

• ʻAʻole kūpono ka hoʻohana ʻana o nā Suppositor no nā mea a pau
• ʻAʻole i loaʻa i ke ʻano papa.

Clindamycin

Nizhpharm (Serbia)
Kūʻai - mai 167 r

ʻO ka hana ikaika ka mea like pū me ka lako. Loaʻa i nā ʻano capsule.

NOHO

• Hoʻopele ka hoʻohanaʻana i kahi laila (capsules).
• Ua haʻahaʻa ke kumu.

ʻĀpuka:

• Contraindicated ma ka hāpai ʻana
• ʻO nā hopena like like me Dalacin C.

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

I loko, nā pākeke: 150 mg i kēlā me kēia 6 mau hola, i nā hōʻeha maʻi, hiki ke hoʻonui ʻia i hoʻokahi manawa i 300-450 mg o ka lāʻau lapaʻau. ʻO nā keiki: 8-25 mg / kg / lā (e pili ana i ka nui o ka maʻi), i hoʻokaʻawale ʻia i nā 3-4 maʻi.

I ka mālamaʻana i ka colpitis i hoʻoiho ʻia e Chlamydia trachomatis, 450 mg e kuhikuhi ʻia i 4 mau manawa i kahi lā no 10-14 lā.

Iā m / i a i loko / i: makua - 300 mg 2 mau manawa i kahi lā. No nā maʻi haʻahaʻa - 150-300 mg 2-4 mau lā i ka lā, no nā maʻi ʻino - 1.2-2.7 g / lā no nā inikua 2-4. Me nā hoʻoulu ʻia ʻana o ke ola, hiki ke hoʻonui ʻia ka nui o ka iv ma 4.8 g / lā.

Kuhi ʻia nā keiki i ka 10-40 mg o ka lāʻau lapaʻau / kg / lā, i māhele ʻia i 3-4 mau pona.

No ka lula iv, hoʻomoʻa i kahi kahe o ka ʻaʻole i kiʻekiʻe ma mua o 6 mg / ml, e hoʻokele ʻia ka hopena i hoʻoheheʻe ʻia i loko o kahi pā no 10-60 mau minuke.

Nā papa inoa o ka dilution a me ka lōʻihi o ka infusion: ka nui, ka nui o nā hānā a me ka lōʻihi o ka infusion (kū hoʻokahi): 300 mg - 50 ml - 10 min, 600 mg - 100 ml - 20 min, 900 mg - 150 ml - 30 min, 1200 mg - 200 ml - 45 mau minuke ʻAʻole hoʻolako ʻia ka hoʻopuka ʻana o ka mea ma mua o 1,2 g i ka manawa 1 o ka infusion.

Hoʻohana ʻia kēia mea hoʻonā i loko o 24 mau hola mai ka lā o ka hoʻomākaukau. I ka mālamaʻana i ka colitis i hoʻokumu ʻia e Clostridium difficile, hui pū me ka vancomycin no 10 mau lā ma 500 mg - 2 g i kēlā me kēia lā, ka wā i hoʻokaʻawale ʻia i 3 a 4 mau ʻano like.

ʻO nā mea maʻi me ka maʻi ʻole o ka maʻi hepatic e koi aku no ka hoʻoponopono ʻana i ka wī.

Ka hana lāʻau lapaʻau

Antibiotic o ka hui o lincosamides. He wahi ākea ka nui o ka hana, ka bacteriostatic, nakinaki i ka 50S subunit o ka membosa ribosomal a pale aku i ka synthesis o ka protein ma loko o ka pūnaewele mikrobial. I ka pilina me ka nui o ka cocci mauʻano, hiki i ka hopena bactericidal. ʻO ka ʻauhau kūʻē iā Staphylococcus spp. (komo pū me ka penicillinase e hana nei i ka Staphylococcus epidermidis), Streptococcus spp. . (me Bacteroides fragilis a me Prevotella melaninogenica), Fusobacterium spp., Propionibacterium spp., Eubacter spp., Actinomyces spp.

ʻO ka hapanui o nā mana o Clostridium perfringens e pili i ka lāʻau, eia naʻe, no ka mea, ʻo nā ʻano clostridia ʻē aʻe (Clostridium sporogenes, Clostridium tertium) kūpaʻa i ka lāʻau lapaʻau, hoʻoholo ʻia ka manaʻo o ka antibiotika no nā maʻi i hoʻoiho ʻia e Clostridium spp.

ʻAʻole hiki i ke haukapila ke kūʻē i ka Mycoplasma pneumoniae, Haemophilus influenzae, Helibacter pylori, Neisseria meningitidis, Neisseria gonorrhoeae, Ureaplasma urealyticum.

Ke kū nei ka pale kūʻē ma waena o Dalacin C a me lincomycin. Maʻaola kūpono i ka mālama ʻana o ka kaʻa diphtheria asymptomatic (papa i nā hebedoma i ka hopena, waha).