Hoʻopau paʻa nā antibiotics i ke ola o ke kanaka. I kēia manawa hiki iā ʻoe ke loaʻa nā lāʻau lapaʻau antimicrobial, sabati antibacterial, gel bactericidal a i nā holoi holoi, a pēlā aku. Akā e hoʻohana pono āpau i nā mea āpau. ʻO ka maʻamau inā hiki i ka lāʻau lapaʻau. E haʻi aku ka ʻatikala o kēia lā iā ʻoe i ka mea o Gentamicin-Akos. No ka mea ka mea a ka ʻaila, a i nā mea ʻoi aku ka maikaʻi o ka hōʻole ʻana, e aʻo hou ʻoe.

Lapaʻau lāʻau

Ma hope o ke noi ʻana, ua aneane ʻole ka huahana e waho. Hoʻomaʻamaʻa koke ka lāʻau lapaʻau ma ka pūnaewele o ke aʻa a hōʻeha paha.

Ma hope o ka hoʻomoe intramuscularly, lawe koke ʻia ka mea ikaika. ʻO ka maʻa me ka urine a me ka bile. Hoʻopaʻa iki ia i ka protein koko koko.

Hiki i ke ʻano o ka hoʻopau ʻana o ka maka i ka maka i ʻike ʻia ʻole he waiwai ʻole.

Nā Hoʻohui

ʻAʻole mea i hoʻolilo ʻia ka poni no nā kumu therapeutic inā he māhuahua nui ka mālamalama o kekahi mea o ka lāʻau (me ka mōʻaukala) a aminoglycosides, uremia, neuritis auditory, nā hana hoʻopalapula nui.

Hoʻohana ʻia ka Gentamicin Akos i ka mālama ʻana i nā leʻaleʻa maka bakalula.

Lapaʻau lāʻau

Hoʻopili ia i nā subunit 30S o nā ribosa a hoʻonāukiuki i ka synthesis o ka protein, pale i ka hoʻokumu ʻana o kahi kiʻina o ka halihali a me ka mea hoʻouna RNA, a me ka waeʻinā genetic ke heluhelu pono ʻole a ua haku ʻia nā ʻōmole hana ʻole. I nā kīʻaha kiʻekiʻe, ua hoʻonāukiuki i ka hana huna o ka membrane cytoplasmic a hoʻokō i ka make o nā microorganisms.

Hoʻomaʻaʻa i ke kū'ē ʻana i nā maʻi he nui-maikaʻi a me kaola. He mea hoʻonāukiuki nā gram-negative - Proteus spp. Mahele nui i ka gentamicin (MPC ma mua o 4 mg / l). . (komo pū me ka penicillin-kū), ʻoluʻolu me ka MPC 4-88 mg / l - Serratia spp., Klebsiella spp., Pseudomonas spp. (me Pseudomonas aeruginosa), Acinetobacter spp., Citrobacter spp., Providencia spp. Noho (MPC oi aku ma mua o 8 mg / l) - Neisseria meningitidis, Treponema pallidum, Streptococcus spp. (komo pū me Streptococcus pneumoniae a me nā pūʻulu D strains), Bacteroides spp., Clostridium spp., Providencia rettgeri. I ka hui pū me nā penicillins (e pili ana i ka benzylpenicillin, ampicillin, carbenicillin, oxacillin), e hana ana i ke ʻano o ka pā o ka pā o nā microorganisms, e hana ana i ka fīlocole Enterococcus, Enterococcus faecium, Enterococcus durans, Enterococcus faiumium nā ʻano ʻokoʻa (me Streptococcus faecalis liguifaciens, Streptococcus faecalis zymogenes), Streptococcus faecium, Streptococcus durans. Ke kū mālie nei ka pale ʻana o nā microorganisms i ka gentamicin, akā naʻe, hiki i nā keaka ke kū ʻole i ka neomycin a me ke kanamycin, e hōʻike pū ʻia aku hoʻi ke kū'ē i ka gentamicin (kū i ke kūlike me ke kū ʻole). ʻAʻole pili i ka anaerobes, nā fungi, nā maʻi, nā protozoa.

Ke keu

Nā hōʻailona: ka i hoʻoemi ʻia o ka hopena neuromuscular (hopu i ka hanu).

Hoʻomaʻamaʻa: nā lāʻau lapaʻau anti-cholinesterase (Proserinum) a me ka hoʻomākaukau ʻana i ka calcium (5-10 ml o kahi wai o 10% o ka calcium chloride, 5-10 ml o kahi papa o 10% o ka calcium gluconate) i hoʻopuka ʻia i loko o nā pākeke. Ma mua o ka hoʻopuka ʻana iā Prozerin, ua mālama ʻia ʻo ka atropine i ka wai o 0.5-0.7 mg iv, e manaʻo ʻia ka piʻi ʻana o ka pulse, a ʻo 1.5-2 mau minuke hope loa, 1.5 mg (3 ml o kahi hopena 0,05%) o Prozerin e mālama ʻia. Inā lawa ʻole ka hopena o kēia ʻauʻau, ʻo ia nō ka hopena o Prozerin e lawelawe hou ʻia (me ke ʻano o bradycardia, ua hāʻawi ʻia i kahi maʻi hou o ka atropine). Hāʻawi ʻia nā keiki i nā lako hoʻohui calcium. I nā hihia koʻikoʻi o ka hanu kaumaha, koi ʻia ka pono o ka uila. Hiki ke hoʻoulu ʻia e ka hemodialysis (ʻoi aku ka maikaʻi) a me ka dialysis peritoneal.