Nā kuikawa o ke kano rosuvastatin > Nā lāʻau lapaʻau

Kēia nā loiloi o ka lāʻau rosuvastatin canon, nā lāʻau lapaʻau e hoʻololi ʻia i nā hua o kā lākou hopena ma ke kino, ka mea hoʻokahi a me kekahi mau mea like a pau. Ke koho ʻana i nā unuhi, e noʻonoʻo wale ʻaʻole i kā lākou kumukūʻai, akā no ke aupuni o ka hana a me ka maikaʻi hoʻi o ka mea hana.

ʻO ka wehewehe ʻana i ka lāʻau lapaʻau
Ka papa inoa o nā mea kikoʻī a me nā kumukūʻai
Hoike Mai
Nā ʻōlelo kuhikuhi i ka hoʻohana ʻana

ʻO ka wehewehe ʻana i ka lāʻau lapaʻau

Canu Rosuvastatin - He lāʻau lapaʻau hypolipidemic, he mea koho kūleʻa koho HMG-CoA reductase, ka mea e hoʻololi ai i ka 3-hydroxy-3-methylglutaryl coenzyme A i ka mevalonate, kahi mea mua o ka cholesterol.

ʻO ka pahuhopu nui o ka hana nā mea lewa, kahi e lawe ai ka synthesis a me ka LDL catabolism. Mālama i ka hana o HMG-CoA reductase (90% o ka rosuvastatin i kahe i loko o ke koko). Hoʻonui ia i ka nui o nā receptors LDL ma ka ʻaoʻao o nā hepatocytes, e hoʻonui ana i ka piʻi a me ka catabolism o LDL, e alakaʻi ana i ka pale ʻana o ke kāpili ʻana o ka VLDL, e hōʻemi ana i ka nui o ka helu LDL a me VLDL. Hoʻēmi i ka pane ʻana o ka cholesterol LDL, ʻaʻole ka HDL cholesterol, ka VLDL kolamu, ka nui kolamu, triglycerides, triglycerides VLDL, apolipoprotein B (ApoV), ka māhele o ka LDL cholesterol / LDL cholesterol / kolesterol, kolesterol, kolesterol. -HDL, ApoV / ApoA-1, e hoʻonui i ka kaʻe o ka HDL kolamu, ApoA-1.

Hoʻomohala ka hopena therapeutic i loko o ka 1 hebedoma ma hope o ka hoʻomaka ʻana o ka hoʻomaʻamaʻa, ma hope o 2 mau pule a hiki i 90% o ka hopena hiki loa, hiki i ka hopena therapeutic loa ke loaʻa i ka 4 wiki o ka lapaʻau a mālama ʻia me ka hoʻohana maʻamau o ka lāʻau lapaʻau.

Pōmaikaʻi ʻo ia i nā mea maʻi me ka hypercholesterolemia, me ka ʻole a hypertriglyceridemia (e pili ana i ka lāhui, ka wahine a i ʻole ka makahiki), ʻo ia hoʻi i nā mea maʻi me ka maʻi mellitus a me hypercholesterolemia familial.

Hoʻomaopopo ka hopena hoʻohui me ka fenofibrate (e pili ana i ka hoʻohaʻahaʻa ʻana i ka ʻike o ka triglycerides) a me ka hoʻōla molotinik i ka lipid e hoʻohaʻahaʻa i nā pale (e pili ana i ka hoʻohaʻahaʻa ʻana i ka neʻe o ka HDL cholesterol).

Nā hōʻailona no ka hoʻohana ʻana

- ʻO ka hypercholesterolemia maʻamau ʻo Fredriksen (type IIa, me ka familial heterozygous hypercholesterolemia) a i ʻole ka palaka ʻana i ka hypercholesterolemia (type IIb) i ke ʻano o ka ʻai, i ka wā e ʻai ai nā meaʻai a me nā ʻano lāʻau lapaʻau ʻole ʻē aʻe (hoʻomaʻamaʻa, hoʻemi kaumaha) ʻaʻole lawa.

- Ka ʻohana homozygous hypercholesterolemia ma ke ʻano he meaʻaiʻai a me nā haʻahaʻa haʻahaʻa lipid haʻahaʻa (no ka laʻana, ʻo LDL apheresis), a i nā mea ʻē aʻe, ʻaʻole pono ka hopena o ia ʻano maʻi.

- Hypertriglyceridemia (type IV ma muli o Fredricksen) i mea hoʻohui i ka meaʻai.

- Ke hoʻolōʻihi i ka holomua o ka atherosclerosis me kahi mea hoʻohui i ka meaʻai i nā mea maʻi e hōʻike ʻia ana ka lāʻau e hōʻemi i ke kaila o ka kolamu a me LDL-C.

- Ke pale mua ʻana o nā hōʻeha cardiovascular nui (stroke, myocardial infarction, arterial revascularization) i nā poʻe maʻi maʻi ʻole me nā hōʻailona koʻikoʻi o ka maʻi arterio coronary, akā me ka piʻi o ka ulu ʻana (ma mua o 50 mau makahiki no nā kāne a ʻoi aku ma luna o 60 mau makahiki no nā wāhine, hoʻonui ʻia ka C-reactive ka protein (ʻoi aku ma mua o 2 mg / l) ma mua o ka liʻiliʻi i kekahi o nā mea e pili ana i ka hopena, e like me ka arterial hypertension, haʻahaʻa haʻahaʻa o ka kolamu HDL, ka ulaula, kaʻikepili ʻohana i ka hoʻomaka mua o ka maʻi naʻau coronary).

Nā Hoʻohui

No nā papa o 10 mg a me 20 mg:

- hoʻonuiʻike i ka rosuvastatin a i ʻole kekahi o nā mea pono o ka lāʻau,

- nā maʻi o ka pēpē i ka hana ikaika, me ka hoʻomau mau ʻana i ka hana serum o nā transaminases a me nā hoʻonui hou aʻe o ka hana o nā transaminases i ka serum koko (ʻoi aku ma mua o 3 mau manawa e hoʻohālikelike ʻia me ka palena palena palena maʻamau).

ʻO ka hōʻeha o ka renal impairment (ʻo ka hana hoʻopihapiha (CC) i lalo o 30 ml / min),

wahine: wahine hapai, lactation, nele i nā ala kūpono o ka contraception,

-pipihope i kūkulu ʻia i ka hoʻomohala ʻana o nā hoʻopiʻi myotoxic,

-Nā keiki ma lalo o 18 makahiki.

No nā papa 40 mg:

- hoʻonuiʻike i ka rosuvastatin a i ʻole kekahi o nā mea pono o ka lāʻau,

wahine: wahine hapai, lactation, nele i nā ala kūpono o ka contraception,

nā mea maʻi me nā mea e pili ana i ka hoʻomohala ʻana i ka myopathy / rhabdomyolysis, ʻo ia hoʻi:

ka pilikia ʻole o ka hōʻino ʻana o ka maʻi (CC ma mua o 60 ml / min),

- he moʻolelo pilikino a pilikino paha ma ka maʻi ʻōiwi.

- myotoxicity i nā maʻi e loaʻa ana i ka mōʻaukala o nā HMG-CoA reductase inhibitors a i nā fibrates paha,

- make waiʻona nui,

- nā hana e hiki ke alakaʻi i ka hoʻonui ʻana i ka plasma plasma o ka rosuvastatin,

- ka manawa like o nā fibrates,

--inawaena o ka lahui Asia,

-Nā keiki ma lalo o 18 makahiki.

No nā papa o 10 mg a me 20 mg:

ʻO ka hele mai o ka hopena o ka myopathy / rhabdomyolysis - ka hope ʻole o ka papaleka, hypothyroidism, kahi moʻolelo pilikino a ʻohana paha e pili ana i ka maʻi ʻōiwi a me ka mōʻaukala mua o nā maʻi a me nā mea ʻē aʻe HMG-CoA reductase inhibitors a fibrates, ka paulele paulele ʻana, ma mua o 65 mau makahiki, nā kūlana i ʻike ʻia ai ka hoʻonui. ka hoʻoliʻi plasma o ka rosuvastatin, kaʻi (ka lāhui Āhia - Iapana a me Kina), e hoʻohana pū ana me nā fibrates, kahi mōʻaukala o ka maʻi ate, sepsis, arterial hypotension, mahele nui, trauma, metabolic koʻikoʻi, pilikia endocrine a electrolyte paha, a i ʻole i nā lawelawe hoʻokele ʻole.

No nā papa 40 mg:

ʻOi aku ka maikaʻi o ka renal rula (CC ma mua o 60 ml / min), ma mua o 65 mau makahiki o ka makahiki, ka mōʻaukala o nā maʻi o ka puʻuwai, sepsis, hypotension, ka hoʻokō nui, nā trauma, ka metabolic koʻikoʻi, ka endocrine a me ka electrolyte hoʻonāukiuki a i ʻole ka hoʻomālamalama ʻole.

ʻO nā mea maʻi me ka palaleka o nā leʻaleʻa: ʻaʻohe data a i ʻike a me ka hoʻohana ʻana i ka lāʻau lapaʻau i nā mea maʻi me ka helu kiʻekiʻe ma mua o 9 ma ke kiʻekiʻe Child-Pugh.

Hoʻohana i ka wā hāpai a i ka wā o ka umauma: Rosuvastatin ua contraindicated ma ka hāpai ʻana a me ka lactation. No ka mea he mea nui ka kolamu a me nā mea i hoʻohuihui ʻia mai ka cholesterol ke hoʻonui i ka ulu ʻana o ka pēpē, ʻo ka hiki ke kūpono i ka hoʻēmi ʻana i ka HMG-CoA reductase ma mua o ka hoʻohana ʻana i ka lāʻau lapaʻau i ka wā hapai.

Inā loaʻa ka hopena hapai i ka wā o ka hōʻola, pono e hoʻokuʻu koke i ka lāʻau.

Pono nā wahine o nā makahiki hānau hānau i nā ala kūpono o ka contraception.

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

I loko, pono e hoʻokaʻawale ʻia a ʻāʻī paha ka papa, hoʻokaʻawale ʻia, holoi ʻia me ka wai e ʻike ʻia, hiki ke lawe ʻia i kēlā me kēia manawa o ka lā, me ka manaʻo o ka meaʻai. Inā e pono ke lawe i ka lāʻau lapaʻau ma loko o kahi lāʻau o 5 mg, pono ke hoʻokaʻawale kahi papa me kahi maʻi o 10 mg.

Ma mua o ka hoʻomaka ʻana i ka mālama ʻana me Rosonvastatin Canon, pono e hoʻomaka ka mea maʻi e hahai i ka maʻamau hypocholesterolemic diet a hoʻomau ma muli o ia i ka wā e mālama ai. Pono ke koho o ka lāʻau lapaʻau e koho kuokoa i ka pahuhō o nā pahuhopu a me ka pane ʻana i ka therapeutic i ka mālama ʻana, me ka noʻonoʻo ʻana i nā ʻōlelo i kēia manawa i nā pae lipid kiko.

ʻO ka papa hoʻomaka i hoʻomaka ʻia no nā poʻe maʻi e hoʻomaka ana e lawe i ka lāʻau lapaʻau, a no nā mea maʻi i hoʻoneʻe ʻia mai ka lawe ʻana i nā HMG-CoA reductase inhibitors, pono ʻo 5 mg (1/2 papa o 10 mg) a i ʻole 10 mg o ka lāʻau i hoʻokahi manawa i ka lā.

Me ka hoʻokolohua hui pū ʻana o Rosuvastatin Canon me gemfibrozil, fibrates, ka waikiko nikotinic i loko o kahi pākaʻi ʻoi aku ma mua o 1 g / lā, ka pona i ʻōlelo mua ʻia o ka lāʻau ʻo 5 mg (1/2 papa o 10 mg).

Ke koho ʻana i kahi pualikoa mua, pono kekahi e alakaʻi e ka pae kolikino pākahi a noʻonoʻo i ka hiki pono o ke ʻano o nā ʻōwili cardiovascular, a he mea pono no hoʻi e nānā i ka hopena kūpono o ka hopena o ka hopena. Inā loaʻa, hiki ke hoʻonui ʻia ka pākeke ma kahi he nui ma hope o 4 hebedoma.

Ma muli o ka hiki ke hoʻomohala ʻana i ka hopena o ka hopena inā ke kaomi ʻana i kahi maʻi o 40 mg, hoʻohālikelike ʻia me nā haʻahaʻa haʻahaʻa o ka lāʻau, e hoʻonui ana i ka dosis i 40 mg, ma hope o ka nui o ka maʻi hou aʻe ma mua o ka hopena i hoʻolako ʻia no 4 mau wiki o ka maʻi, hiki ke hana ʻia i nā mea maʻi me ka maʻi koʻikoʻi ka helu o ka hypercholesterolemia a me ka palena kiʻekiʻe o nā hoʻopiʻi o ka maʻi cardiovascular (ʻoi aku hoʻi i nā poʻe maʻi me ka hypercholesterolemia familial) ʻaʻole i hoʻokō i ka hopena makemake a loaʻa i ka hopena i ka wā e lawe ai i kahi momona o 20 mg, a e ʻike ʻia e ia. cha. ʻAno ke kiaʻi ʻana i ka poʻe maʻi e loaʻa i ka lāʻau lapaʻau ma loko o kahi mīkala o 40 mg.

ʻAʻole kōkua ʻia ka hoʻohana ʻana i kahi pākēnē o 40 mg ma nā maʻi e ʻike ʻole i kekahi kauka. Ma hope o 2 mau hebedoma e pili ana i ka mālama ʻana a me / a me ke hoʻonui ʻana o ka nui o ka lāʻau o ka lāʻau, pono ka nānā ʻana o ka metabolism lipid (pono ʻia ka hoʻoponopono ʻana inā pono).

Nā maʻi maʻi ʻelemakule.

I nā mea maʻi me ka hōʻemi ʻole ʻana a me ka hoʻololi ʻole, ʻaʻole i koi ʻia ka hoʻoponopono ʻana. Hoʻohana ʻia ka hoʻohana ʻana o nā āpau āpau o ka lāʻau i ka poʻe maʻi me ka hōʻeha ʻole o ka renal (CC ma mua o 30 ml / min). Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau lapaʻau ma kahi o 40 mg o nā maʻi i loko o nā mea maʻi me ka hana renal épole hāneʻa (CC ma mua o 60 ml / min). No ka poʻe maʻi me ka hana renal hāmeʻa maʻalahi, e kuhikuhi ʻia i kahi manawa mua o 5 mg (1/2 papa o 10 mg).

ʻO nā maʻi me ka palaleka pale: rosuvastatin ua contraindicated i nā maʻi me nā maʻi pūlohi ikaika. ʻAʻoheʻike me ka hoʻohana o ka lāʻau lapaʻau i nā mea maʻi me ka hōʻoki ʻana o ka maʻi ma luna o ka 9 ma luna o ka pālaha Keiki-Pugh.

Ke aʻo nei i nā lāʻau lapaʻau pharmacokinetic o rosuvastatin i nā poʻe maʻi e pili ana i nā ʻano like ʻole o ka iwi, ua ʻike ʻia ka nui o ka neʻe ʻana o ka systemic o rosuvastatin ma waena o Iapana a me Kina. Pono e noʻonoʻo ʻia kēia ʻoiaʻiʻo i ka wā e hoʻohana ana iā Rosuvastatin Canon ma kēia pūʻulu o nā maʻi. Ke hoʻohana nei i nā kaila o 10 mg a me 20 mg, ʻo ka paona hoʻomaka hoʻomaka ʻana no nā mea maʻi o ka lāhui Asia he 5 mg (1/2 papa o 10 mg). ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau i kahi maʻa o 40 mg ua hoʻohālikelike ʻia i nā mea maʻi o ka lāhui ʻAsia.

ʻO nā maʻi maʻi Myopathy-prone

Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau lapaʻau ma kahi o 40 mg o ka maʻi i loko o nā mea maʻi me nā mea e hōʻike ana i kahi predisposition i ka hoʻomohala ʻana i ka myopathy. Ke hoʻokomo nei i nā kaila o 10 mg a me 20 mg, ʻo ka paona hoʻomaka hoʻomaka ʻana no kēia pūʻulu o nā maʻi e 5 mg (1/2 papa o 10 mg).

I ka manawa e hoʻohana ai me ka gemfibrozil, ʻaʻole pono ka nui o ka lāʻau lapaʻau ma mua o 10 mg / lā.

Ka hana lāʻau lapaʻau

ʻO Canon Rosuvastatin - kahi lāʻau mālama lipid-kaila, kahi pale hoʻokaʻawale koho HMG-CoA reductase. Pōmaikaʻi ʻo ia i nā mea maʻi me ka hypercholesterolemia, me ka ʻole a hypertriglyceridemia (inā paha o ka lāhui, ʻano o ka wahine a i ʻole ka makahiki), ʻo ia hoʻi i nā mea maʻi me ka maʻi mellitus a me ka hypercholesterolemia familial.

Hoʻomaopopo ka hopena hoʻohui me ka fenofibrate (e pili ana i ka emi ʻana o ka neʻe o TG) a me ka waikika nikotinic i nā lipid e hoʻohaʻahaʻa i nā wai (e pili ana i ka emi ʻana o ka neʻe o ka HDL-C).

Nā analogue a me nā mea e pili ana i ka lāʻau rosuvastatin: papa inoa kūʻai

ʻO Rosuvastatin kahi lāʻau lapaʻau kaulana i hoʻohanaʻia i ka mālamaʻana i nā maʻi o ka ʻōnaehana cardiovascular.Mālama ka hāmeʻa i ka kolamu ma ke kino a hōʻemi i ka hōʻeha o ka maʻi naʻau. ʻO ka ʻōmaʻomaʻo no ka lawe ʻana i ka lāʻau lapaʻau ka pili ʻana i nā ʻano āpau o ka hypercholesterolemia, hoʻohui i ka dyslipidemia, atherosclerosis, myocardial infarction, ka ʻeha, ka maoka.

ʻO ka mea hana o kēia lāʻau lapaʻau o ka inoa like me kona inoa ʻo rosuvastatin. He ʻōkohu hypolipidemic mai kēia pūʻulu o nā satins. Kuhi puka - nā papa. ʻAʻole kuhikuhi ʻia ka lāʻau lapaʻau no nā keiki ma lalo o 18 makahiki o kona mau makahiki, i ka wā hāpai, i ka wā lactation. Ua hua ʻia ʻo Rosuvastatin ma Rūsia, a me kekahi mau ʻāina CIS a i waho.

ʻO ke kumukūʻai kūpono o kahi lāʻau lapaʻau he 500-700 rubles, e hilinaʻi ana i ka nui a me ka helu o nā papa i ka pā. ʻO ke kumu kūʻai o ka lāʻau lapaʻau ka pono i ka ʻimi ʻana no kahi wili no ka lāʻau maʻalahi. Hoʻopili i nā loli a me nā hōʻailona like ʻole a me nā mea like ʻole, akā ʻaʻole like kekahi mau contraindications a loaʻa paha i kahi pae.

Inā kauoha ke kauka i ka rosuvastatin, ʻoi aku ka liʻiliʻi o nā analogues ma mua o kēia lāʻau lapaʻau mai waena o nā lāʻau lapaʻau mai kahi mea hana.

ʻO ka inoa o ka lāʻau lapaʻau	ʻO ke kumukūʻai kumukūʻai i nā rubles	Hōʻanoʻike
Akorta	550–880	Ua kuhikuhi ʻia ka lāʻau lapaʻau no ka hypercholesterolemia mua e like me Fredricksen, hyperglyceridemia, e lohi i ka hoʻomohala ʻana o ka atherosclerosis, i mea e pale ai i ka hoʻomohala ʻana o nā maʻi cardiovascular maʻamau.
Mertenil	450–1750	Ua hōʻike ʻia ka lāʻau lapaʻau no nā kūlana dyslipidemic, me ka hypercholesterolemia. Pono ka lawe ʻana i ka lāʻau lapaʻau me ka meaʻai maʻamau. Lawe ʻia nā papa pākuʻi, me ka manaʻo o ka intake meaʻai, holoi ʻia me ka wai.
Canu Rosuvastatin	400–710	ʻO ka lipid-hoʻohaʻahaʻa i ka hopena o ka lāʻau e hoʻohaʻahaʻa i ka kolamu holoʻokoʻa. ʻO ka analogue kūʻai kumu kūʻai maikaʻi loa e kūʻai nui ʻia ai ma ka Lūkini

Nā mea hoʻohalike o Ukrainian

E noʻonoʻo i nā analogues haʻalulu o ka hana makeuk Iukia. Aia ka papa inoa i nā kumukūʻai kokoke a me kahi wehewehe pōkole o ka lāʻau lapaʻau.

Atorvacor. ^ E Ha yM. Nā papa liʻiliʻi me ka atorvastatin ma ke ʻano he mea hoʻoikaika. Hana ia i ka hana o ke kīpē ʻana i ka pae o ka kolamu a me ka lipoprotein i loko o ke koko koko, e lawe ana i kāna hana ma ka puʻuwai o ka mea maʻi. Hiki ke kuhikuhi i ka lāʻau i nā keiki ma hope o ke kauwela 10 me ka familial heterozygous hypercholesterolemia ma ke ʻano heʻano nui. ʻO ka awelika kumukūʻai ʻo 140-220 mau rubles.
ʻO Vasostat. ^ E Ha yM. Ke lāʻau lapaʻau haʻahaʻa-hoʻēmi, ʻo ka waiwai ikaika ka simvastatin, ka hopena maikaʻi ma ka lipid metabolism ma ke kino. Lawe ʻia ka lāʻau lapaʻau. Hoʻohālikelike ʻia ke koho ʻana ma ka hihia o ka hōʻaʻe o ka ate. ʻO ka kumukūʻai kumukūʻai ʻo 110-180 mau rubles.
Lovastatin. ^ E Ha yM. Hoʻopau ka mea hana i ka hyperlipoproteinemia, kōkua i ka hoʻonuiʻana i ka synthesis o cholesterol i loko o ka puʻuwai o ka mea maʻi. Hoʻololi ʻia ka lāʻau lapaʻau me ka apolipoprotein B a me nā triglycerides. ʻO ka hopena paʻa o ka hopena me ka lāʻau lapaʻau e loaʻa i nā lā 14 ma hope o ka hoʻomaka ʻana o ka lawe ʻana i nā papa. ʻO ka mea nui ka lovastatin. ʻAʻole i kuhikuhi ʻia i ka wā o ka hāpai a me ka lactation. ʻO ka awelika kumukūʻai he 155-70 rubles no nā pā o 30 mau papa.

Generics Belarusian

Aia ka papa ma lalo nei me ka inikini Belarusian generics rosuvastatin, e kōkua i ka hoʻoponopono ʻana i ka pilikia o ka mea e hoʻohuli ai ka lāʻau lapaʻau me.

ʻO ka inoa o ka lāʻau lapaʻau	ʻO ke kumukūʻai kumukūʻai i nā rubles	Hōʻanoʻike
Rosutatin	210–550	Aia ka lāʻau lapaʻau i nā papa me rosuvastatin ma ke ʻano he mea ikaika. Loaʻa ia nā hōʻailona no ka hoʻohana like ʻana me ka loea hōʻike. He nui nā contraindications i ka lāʻau.
Atorvastatin	120–600	ʻO ka mea kūleʻa kūʻai loa no ka rosuvastatin. No ka lāʻau ka lāʻau i ka laʻana o ka lāʻau laʻa o lipid-hoʻemi haʻahaʻa a kuhikuhi ʻia i ka mālama ʻana i nā kūlana i pili me ka piʻi nui o ka cholesterol. ʻAʻole i kuhikuhi ʻia ka lāʻau lapaʻau i ka wā o ka hapai, lactation, me nā keiki ma lalo o 18 makahiki o kona mau makahiki.
Lipromak LF	135–550	ʻO ka mea ikaika i ka lāʻau lapaʻau is atorvastatin. Hoʻemi i nā pae lipoprotein koko. Hoʻoulu ka lāʻau lapaʻau i ka hana ikaika i loko o ka puʻuwai o ka mea maʻi, ʻoiai ua hala ia i loaʻa ka synthesis cholesterol.Ma ka hoʻohana ʻana i nā keiki, hiki ke mālama ʻia ma kahi hapa o ka nui ma mua o 20 mg.

Nā huaʻōlelo ʻē aʻe o nā haole

ʻO nā kumukūʻai import modern no ke kumukūʻai kiʻekiʻe a ʻaʻohe hapa iki:

ʻOkaʻohana. ^ E Ha yM. Hoʻolaha kūlike kālā o rosuvastatin, loaʻa i nā papa. ʻO kahi lāʻau lapa-lipid kaulana. Hoʻōla ʻia ka lāʻau i ka UK, Puerto Rico. ʻO ka awelika kumukūʻai he 515–5900 rubles.
Mertenil. ^ E Ha yM. Ka pūnaehana o ka lāʻau me ka rosuvastatin ma ke ʻano he mea hoʻoikaika. Hoʻemi i ka kūlana o ka piʻi nui o ka cholesterol i ke kino. ʻO ka'āina kahi - Hungary. ʻO ka awelika kumukūʻai he 510-1700 rubles.
Rosistark. ^ E Ha yM. ʻO ka lāʻau lapaʻau mai ka lāʻau lapaʻau lāʻau o satins. Hoʻohana ʻia ia e mālama i ka hypercholesterolemia i nā poʻe maʻi pākeke ma mua o 18 mau makahiki. Loaʻa i Kroasia. ʻO ka kumu kumukūʻai he 250-790 rubles.

ʻO nā ʻano āpau ma ka rosuvastatin, a me nā mea hoʻopili a me nā mea pili i pili, e hōʻike ʻia i nā pā hale kūʻai ma nā kūlanakauhale ʻo Lūkini.

Pono e mālamai ka mea i hoʻoholo ʻia ai ke koho i kahi lāʻau lapaʻau kūikawā pono, e pono mau ia e mālama ʻia, ʻaʻole ia e ʻae i kahi mea o nā lāʻau hou. ʻO ia ke kumu e hana ai ʻo ka koho hope loa e kekahi kauka loea e hiki ai ke loiloi i ka ʻoihana loea.

ʻO nā papa Canon Rosuvastatin: nā ʻōlelo a me nā hui o 10 a me 20 mg

ʻO Rosuvastatin Canon kahi lāʻau lapaʻau me nā waiwai lipid-hoʻohaʻahaʻa. Aia ka lāʻau i ka pūʻulu o nā statins.

ʻO ka lāʻau lapaʻau he mea hoʻoneʻene koho koho o HMG-CoA reductase, nona ke kuleana no ka hoʻohuli ʻana i ka 3-hydroxy-3-methylglutaryl coenzyme A i ka mevalonate, kahi mea he mua o ka cholesterol.

ʻO ka pahuhopu nui o ka hana a ka lāʻau lapaʻau ka lehelehe, he mea hana e hana ai ke kaʻina o ke kōkelena a me ka catabolism o nā lipoproteins haʻahaʻa haʻahaʻa.

Ke pale nei ka lāʻau lapaʻau i ka hana o HMG-CoA reductase. Ke hoʻohana nei i ka lāʻau lapaʻau, ma kahi o 90% o rosuvastatin e puni i ke koko koko.

Hoʻohana ka hoʻohana ʻana i ka lāʻau lapaʻau i hoʻonui i ka nui o nā mea LDL ma ka membrane o nā hepatocytes, e hoʻonui ana i ka hopu a me ka catabolism o nā lipoproteins haʻahaʻa haʻahaʻa. ʻO kēlā hopena ma ke kino e alakaʻi ai i ka hoʻoemi ʻana i ka pae o LDL i ka plasma.

ʻO ka hopena therapeutic o ka hoʻohanaʻana i ka lāʻau lapaʻau e mālama ʻia i hoʻokahi pule ma hope o ka hoʻomaka ʻana o ka hopena. Ma hope o 2 mau pule, hiki i ka hopena therapeutic kona kiʻekiʻe. Ma hope o kēia manawa, ʻike pinepine ʻia kahi emi haʻahaʻa o ka pae o ka cholesterol i ke kino a hoʻomau ʻia ka hoʻohana mau ʻana i ka lāʻau lapaʻau i mālama ʻia i nā pae i loaʻa i ka wā lōʻihi.

ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau hiki i ke kau ʻana i ka hoʻolilo momona ma muli o ka lawe ʻana i nā lipids nui mai ia mai.

E hoʻokuʻu i ke ʻano a me ka hoʻohuihui huahana

Hana ka mea hana i ka lāʻau i ke ʻano o nā papa. Hoʻopili ʻia ka ʻaoʻao o ka papa me ke kaʻi ʻulaʻula ʻulaʻula.

Aia ke kiko, biconvex Ma ka ʻaoʻao convex, hoʻopilikia ʻia ka pilikia. Ma kahi ʻāpana ʻeka, he ʻano keʻokeʻo keʻokeʻo ka hoʻomākaukau ʻana.

ʻO ka mea hana nui ma ka lāʻau lapaʻau ka rauvastatin calcium. Aia kēia māhele i loko o ka nui e like me ka 10,4 mg, ma ka ʻōlelo o ka rosuvastatin maʻa he 10 mg.

Ma kahi o ka pūhui koʻikoʻi koʻikoʻi, ua hoʻokomo ʻia kēia mau pūhui kemu e pili ana i ka ʻōhumu papa.

calcium hydrogen phosphate dihydrate,
hua pālua pregelatinized,
konekena stearate,
povidone
cellulose microcrystalline.

ʻO ka hoʻonohonoho ʻana o ka pani ʻana o ka kiʻi ʻoniʻoni e pili ana i kēia mau māhele:

ʻUlaʻula Selecoat AQ-01032.
ʻO ka hydrylpropyl methylcellulose.
Macrogol-400.
Macrogol-6000.
Kaapili Titanium
Kūkulu ʻia ka alumini Varnish e pili ana i ka lepo dago Ponso 4R.

ʻO ka mea hana, nā papa i hana ʻia, nā wahi i loko o kahi pehu i ka pehu o PVC. ʻO luna ma luna o ka pahu e uhi ʻia me ka alumini foil.Hoʻopili ʻia kēlā mau pahu pahu ma nā pahu pepa, kahi i waiho ʻia ai nā kauoha no ka hoʻohana ʻana i ka lāʻau lapaʻau.

Loaʻa ka lāʻau lapaʻau i nā papa me nā ʻano like ʻole o ka mea hoʻōla ikaika. I loko o nā lāʻauʻaiʻai, me ka makemake i ka pono, hiki iā ʻoe ke kūʻai i ka lāʻau lapaʻau me ka nui o ka rauvastatin 10, 20 a me 40 mg i hoʻokahi papa.

Pili ke kumukūʻai o ka lāʻau lapaʻau ma ka wahi o ke kūʻai aku ma ka Lūkini Lūkini, ʻo ka hoʻomohala ʻia o ka pahuhopu koʻikoʻi ikaika i ka hoʻokumu ʻana i ka lāʻau lapaʻau a me ka helu o nā papa i hoʻokahi pākahi.

ʻO ke kumukūʻai o hoʻokahi pahu, ma muli o nā ʻāpana i kikoʻī ʻia, hiki ke loli mai 350 a 850 rubles.

Hiki i ka mea maʻi ke kūʻai i ka lāʻau lapaʻau wale nō inā aia ke ʻano lāʻau lapaʻau e komo ai i ke kauka.

Pono e mālama i ka lāʻau ma kahi mahana ʻaʻole iʻoi aku ma mua o 25 tikeleka Celsius ma kahi maloʻo i hiki ʻole ke loaʻa i nā keiki a me nā holoholona. Pono ka wahi e mālama ai i ka wana i ka lā. ʻO ʻelua mau makahiki ka noho o ke ola o ka lāʻau.

Ma hope o kēia manawa, pāpā ʻia ka hoʻohana ʻana i ka lāʻau, pono e hoʻokuʻu ʻia.

Nā hōʻailona a me nā contraindications no ke hoʻohana

Ma mua o ka hoʻohana ʻana i ka lāʻau Rosuvastatin Canon, pono ʻoe e noʻonoʻo pono i nā ʻōkuhi no ka hoʻohana ʻana, nā loiloi e pili ana i ka lāʻau lapaʻau o nā kauka a me nā mea maʻi, a hoʻomaʻamaʻa ʻoe iā ʻoe iho me ke kumukūʻai o ka lāʻau lapaʻau me nā ʻano like ʻole o ka ʻano lāʻau ikaika.

Ke kuhikuhi nei ke alakaʻi i ka hoʻohana ʻana i ka lāʻau lapaʻau e lawe i ka lāʻau lapaʻau wale nō ma hope o ka nīnau ʻana me kāu kauka.

Hoʻoholo ke kauka i ka dosage maikaʻi loa, me ka nānā i nā ʻike a pau e pili ana i ke olakino a me kekahi ʻano pilikino o ke kino o ka mea maʻi.

ʻO nā mea nui no ka hoʻohana ʻana i ka lāʻau lapaʻau e like me nā kuhikuhi i ke hoʻohana ʻana:

ka hele ʻana o ka hypercholesterolemia primale ma muli o Fredrickson (type IIa, me ka familial heterozygous hypercholesterolemia) a i ʻole ka hypercholesterolemia hoʻopili (type IIb) i kumuhana i ka meaʻai, i loko o kēlā mau hanana ka hana o nā lapaʻau non-pharmacological (hana pilikino, hōʻemi ke kaumaha) ʻaʻole lawa.
ka hele ʻana o ka hypercholesterolemia familial, ka hoʻohui ʻana i ka meaʻai a me nā ʻano haʻahaʻa lipid-lowing therapy (no ka laʻana, ʻo LDL-apheresis), a i nā mea i kū ʻole ai ka hoʻohana ʻana o ia ʻano lapaʻau.
ka heleʻana o hypertriglyceridemia (type IV e like me Fredrickson) ma kahi o ka meaʻai i hoʻohana ʻia.

Nā ʻokoʻa o ka hoʻohana ʻana i ka lāʻau lapaʻau ka mea ʻokoʻa ma muli o ke kaona ʻana i nā papa o ka mea hoʻohana nui.

No laila, no nā papa he 10 a me 20 mg o rosuvastatin, aia ka mea maʻi i kēia mau contraindications:

ʻO nā maʻi o ka puʻuwai ma ka hana ikaika o ka holomua, e komo pū ana me ka hana transaminase.
Ka hopena paʻakikī o ka hana a ka lua.
ʻO kahi o nā myopathy i kahi maʻi.
ʻO ka hoʻohanaʻana i ka lāʻau cyclosporin.
ʻO ka manawa o ka gestation a me ka manawa o ka lactation.
Ke hele nei i ka holomua o nā hoʻopiʻi myotoxic.
ʻOi aku ka liʻiliʻi ma mua o 18 mau makahiki.
Hypersensitivity i nā ʻāpana o ka lāʻau.

Ke hoʻohana nei i nā papa me ke ʻano o ka rosuvastatin 40 mg, contraindications no ke hoʻohana ʻana:

renal a me ka nele ole,
hāpai a ʻeha
hana me ka cyclosporine,
ka hiki ʻana o nā maʻi ʻeha ma ka hopena ʻoi ke kūkulu ʻana,
ka noho ʻana ma ke kino o ke kākākūkā haʻi ʻia i nā māhele o ka lāʻau lapaʻau.

ʻO kahi overdose o ka lāʻau lapaʻau i ka mea maʻi e hele nei i ka wā e lawe ana i nā helu he nui i kēlā me kēia lā.

Inā ʻike ʻia kahi overdose, ua kuhikuhi ʻia ka lāʻau lapaʻau a me nā hana ate, a me ka hana CPK, ka nānā ʻia ʻana.

ʻAʻohe mea antidote kūikawā i hoʻohana ʻia i ka wā e hele ai ka overdose. He hana hemodialysis maikaʻi ʻole.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

Hoʻōhoihoi ʻia ka lāʻau lapaʻau, i kēlā me kēia manawa o ka lā, me ke ʻano o ka meaʻai.

E hoʻopau ʻia ka papa papaʻa ʻole me ka ʻole o ka ʻaʻa, ʻo ka lawe ʻana i ka huahana e hele pū me ka inu ʻana i ka wai nui.

I ka hihia o ke kohoʻana i ka lāʻau i loko o kahi waihona o 5 mg, kahi papa me kahi nui o ka māhele ikaika o ka 10 mg hiki ke hoʻokaʻawale i ka hapalua.

Ma mua o ka alakaʻi ʻana i ka lāʻau me Rosuvastatin, koi ʻo Canon e mālama ka mea maʻi i kaʻai hypocholesterol paʻa hou no kekahi manawa. ʻO ka hoʻokō ʻana me ia kai e pono ai no ka hoʻomaka ʻana o ka lāʻau lapaʻau.

Koho ʻia ka nui o nā papa no ka cholesterol e ke kauka e komo ana i ka hopena o nā huli a me nā haʻawina o ke kino o ka mea maʻi ma hope o ka hoʻokomo ʻana i ka meaʻai meaʻai a me kāna ʻano pilikino.

Eia kekahi, ʻo ka nui o ka lāʻau o ka lāʻau e hoʻohana ʻia ana e pā pono i ka kumu o ka papa lāʻau a me ke ʻano o ke ʻano o ka pane o ke kino i ka hoʻohana ʻana o Canon i ka mālama ʻana iā Rosuvastatin.

Wahi a nā ʻōkuhi no ka hoʻohana ʻana, ʻo ka nui o ka lāʻau inapau i hōʻike ʻia ʻia o ka lāʻau he 5 a he 10 mg hoʻokahi i ka lā.

Me ka hoʻohana like ʻana o rosuvastatin me nā fibrates a i ʻole ka nikotinic acid i loko o kahi waihona o ka nui o ke koena ma mua o 1 grama no kēlā me kēia lā, ʻo ka nui ma mua o ka 5 mg hoʻokahi i ka lā.

Ke koho ʻana i kahi mahele, pono e alakaʻi ke kauka e nā hopena o ke ana ʻana i ka nui o ka kolamu ma ke kino o ka mea maʻi a mālama i ka hopena kūpono paha e hoʻomau i ka hoʻopiʻi cardiovascular. Eia kekahi, pono e noʻonoʻo ka loea i ka hopena o ka hopena o ka hopena mai ka hoʻohana ʻana i nā lāʻau lapaʻau i ka hopena o ka hopena.

Inā kūpono, e hoʻoponopono ʻia ka nui o ka lāʻau i hoʻohana ʻia i kēlā me kēia 4 pule.

Hoʻohana ʻia ka hoʻohana ʻia ʻana o kahi waihona he 40 mg i loko o nā mea maʻi me ka maʻi koʻikoʻi o ka hoʻomohala ʻana i ka hypercholesterolemia a ma ke alo o kahi pilikia nui o nā ʻōmole ma ka hana o ka ʻōnaehana cardiovascular o ke kino, me ka ʻike ʻana i ke koko kiʻekiʻe ma kahi maʻi. I ka hihia o ka hoʻohana ʻana i ka nui o ka lae i ʻae ʻia i ka wā o ka mālama ʻana, pono ka mea maʻi ma lalo o ka mālama mau o ke kauka.

Hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau lapaʻau ma ka nui loa ma ke ʻano he mea maʻi me ka maikaʻi ʻole o ka renal a me ka hōʻino ʻana i ka maʻi.

No kēia ʻōpū o nā mea maʻi, ʻo ka dosis i makemake ʻia e 5 mg i kēlā me kēia lā i hoʻokahi pākahi.

Nā hopena ʻaoʻao a me nā hōʻailona o Rosuvastatin Canon

Ma ke kaʻina hana e hoʻohana ai i ka lāʻau lapaʻau, hiki i nā hopena ʻaoʻao ke ulu i ke kino o ka mea maʻi.

Ma muli o ke ʻano o ka hopena pākuʻi ʻia i ka hānō i hoʻohana ʻia a me nā hiʻohiʻona pilikino o ka maʻi o ka mea maʻi.

Mai ka ʻaoʻao o ka pūnaehana pīhoihoi koʻikoʻi, nahā o ka maʻi, nā maʻi ʻeha a, ma nā hihia līpī, hiki mai paha ka luhi hoʻomanaʻo.

Mai ka hopena o ka ʻeha gastrointestinal e hōʻike ʻia e ka hele ʻana o ka constipation, nausea, ka ʻōpū o ka ʻōpū, i nā hanana kaila, i ka hoʻomohala ʻana o ka pancreatitis a me nā jaundice.

Hiki i ka ʻōnaehana hanahana ke pane aku i ka lāʻau lapaʻau me nā mea hōʻike e like me ka wā ʻoi a hōʻoki ʻana i ka hanu.

Mai ka ʻōnaehana musculoskeletal, hiki i ke ʻano o ke myalgia ke hiki. ʻO Myopathies a, i nā hihia paʻakikī, arthralgia.

Ma ka ʻaoʻao o ka ʻōnaehana urinary, hiki ke hōʻike ʻia i kahi hopena i ke ʻano o ka proteinuria, ka huakaʻi peripheral a, ma nā hihia loaʻa ʻole, hematuria.

Ma muli o ka lawe ʻana i ka lāʻau lapaʻau, hiki i ka mea maʻi ke loaʻa i nā hōʻailona o ka maʻi diabetes type 2.

Inā ʻike ʻia kahi hopena ʻaoʻao o ke kino mai ka lawe ʻana i ka lāʻau lapaʻau, hiki ke hoʻololi ʻia i ke kauoha a ke kauka e hele ana me nā analogue.

I kēia manawa, hāʻawi nā mea kanu lāʻau lapaʻau ma mua o 10 o nā meaʻokoʻa maʻalahi i nā mea hoʻohālike o Rosuvastatin Canon.

ʻO kēia mau mea hana:

Akorta,
Mertenil.
Rosart.
Rosistark.
Rosuvastatin Sotex.
Rosuvastatin SZ.
Rosulip.
Rosucard.
Roxer.
ʻĀpana.
Kauoha

ʻO kēia mau lāʻau āpau he hopena like i ka kino, akā he mau ʻokoʻa koʻikoʻi i ke kumukūʻai, hiki i ka mea maʻi ke koho i ka hopena kūpono loa, ma ke kumukūʻai a ma ka hopena therapeutic i hoʻoikaika ʻia i ke kino.

Ke wehewehe nei ka lāʻau Rosuvastatin i ke wikiō ma kēia ʻatikala.

E wehewehe i kāu holi a koho ʻole paha i kahi kāne no nā loiloi: Huli ʻia ʻaʻole ʻike ʻia nō ka hōʻike ʻana.

Rosuvastatin: nā hoʻohālike a me nā kumukūʻai

I nā hihia he nui, ʻo rosuvastatin ka lāʻau lapaʻau ke koho inā pono ke kuhikuhi i nā lāʻau lapaʻau lipid. Eia nō naʻe, aia kekahi mau kumu i hikiʻole ai i kahi mea maʻi ke kūʻai aku i kēia lāʻau lapaʻau.

ʻAno o ka lāʻau lapaʻau i ka ʻoihana hoʻolaʻa kūloko.
Pono ke kumukūʻai nui o ka lāʻau lapaʻau, e pili ana i ka helu kālā o ka mea maʻi, ʻoiai ke hoʻokō i ka hopena therapeutic i makemake ʻia, pono ke noi pono ʻana.

ʻO ka hapa nui o nā lāʻau lapaʻau he analogues. A ʻo "Rosuvastatin", kahi lāʻau lapaʻau o nā noi kiʻekiʻe, i kēia hihia, ʻaʻohe mea ʻē aʻe.

ʻO nā analog nā lāʻau lapaʻau e like me ka mea i ka lāʻau mua, akā na nā huahana huahana e hana ʻokoʻa ma mua o ka mea hoʻokumu.

I nā huaʻōlelo ʻē aʻe, ʻo nā loiloi Rozuvastatin ma ka mākeke lāʻau o ka lāʻau lapaʻau āpau i nā lāʻau āpau i ka hua kōpala ʻano ma rosuvastatin, akā ua hoʻohālikelike ʻia lākou e kahi ʻoihana o nā hui ʻo Japanese ka Shionogi.

He mea kūpono ia e like ʻole i ka poʻe ʻokoʻa o nā mea hana like ʻole o Rosuvastatin, ʻaʻole i pili i ka hopena therapeutic, akā e noʻonoʻo ʻia i nā hihia o ka hoʻomālikelike pono ʻana o kekahi o nā mea like.

Aia ma lalo kahi papa inoa o nā kikoʻī nui o Rosuvastatin, kahi mea, inā pono, hiki ke hoʻololi i ka lāʻau lapaʻau mua. A me kahi papa hoʻohālikelike o ke kumukūʻai o rosuvastatin o nā mea hana like ʻole e hōʻike ʻia. Akā ʻo ka mea mua, pono ʻoe e hāʻawi i ka ʻike pōkole e pili ana i ka huahana mua, i hiki i ka mea kūʻai ke hoʻohālikelike i nā hiʻohiʻonaʻokoʻa ākea o nā kumu maoli a me nā analogues.

ʻO ka hoʻonohonoho ʻana o "Rosuvastatin"

ʻO Rosuvastatin kahi lāʻau lapaʻau mai ka nui o nā lāʻau lapaʻau nui o nā lipid-kaila haʻalulu, nona ka māhele e pili ana i ka hoʻoneʻeneʻe i ka papaʻu (ʻoi aku ka kū'ē ʻana i nā pīkoi kolamu). ʻO ka mea kanu koʻikoʻi ʻo rosuvastatin i ke ʻano o ka paʻakai paʻakai (i.e .: calcium rosuvastatin). ʻO kahi papa inoa o nā mea hoʻonani o nā papa kumu:

ʻO ka Lōmakate Lactose kahi kōmole waiū e kūʻokoʻa mai ka lactose maʻamau e ka neʻe ʻana o kahi kumuwaiwai wai hou i ka hoʻohui kemala. ʻO ka hiki ʻana o kēia hāpana i hana ʻole ʻia ai ka rosuvastatin i nā mea maʻi me ka intolerance lactose pilikino, a i ʻole kahi kakī lactase.
ʻO MCC ka microcrystalline cellulose, kahi mea ikaika ikaika ka mea i komo ʻole ʻia e ke kino kanaka. Hoʻopiʻi ia i nā mea make a me nā mea ʻino ʻē aʻe a laila hoʻoneʻe iā lākou mai ke kino i kahi ʻano i loli ʻole, ʻo ia hoʻi, e kōkua ana i ka hoʻēmi ʻana i ka slagging o ke kino. Hoʻohana maikaʻi ʻia no ka make ʻana a me ka hemahema o nā ʻōpū a me ka ʻōpū. Hoʻomaopopo ʻia kahi nui o nā meaʻai kaiʻai e hoʻohana ma ke ʻano o ka hōʻemi ʻana i ka momona, ʻoiai ka hāʻawi ʻana o ka MSC i ka piha o ka ʻōpū.
ʻO ka Orthophosphate (kalepo phosphate) - he paʻawai pākahi e paʻa ana i ka waikona orthophosphoric a me ka calcium calcium. Loaʻa ia i ka hana palaoa kāwili a hāpai ʻia i ka hoʻopuhina ʻana o ka rosuvastatin.
ʻO ka stearate Magnesium - he paʻakai pākī e pili ana i ka stearic acid a me ka magnesium. He mea hoʻoikaika kanaka no ka huahana pharmacological, kahi i unuhi ʻia i hoʻololi ʻia mai ke kino.
ʻO Crospovidone (kahi kikoʻī paha kahi kikoʻī: povidone, ʻo ia kahi inoa ʻē aʻe) he ʻano ʻōpiopio enterosorbent ākea. Loaʻa iā ia ke komo i nā mea olakino maikaʻi i ke kino (me ka poʻe i hoʻokumu ʻia e ka hana a rosuvastatin ma ke kino o ke kanaka).
ʻO Glyceryl triacetate (triacetin) kahi mea kīʻai e kau nei i ka inoa ʻo E1518, e ʻae ʻia i ka hapa nui o nā ʻāina o ke ao nei (ʻoiai, ma ka Russian Federation a me nā ʻāpana o ka Hui ʻEulopa) a, ma ka noiʻi nui ʻana, ua manaʻo paʻa loa ia no ke kino kanaka. I ka hana ʻana i nā huahana lāʻau lapaʻau he hopena paʻakikī e like me ka moisturizer, plasticizer a me ka solvent.
ʻO Hypromellose (Hydroxypropyl methylcellulose) - he mau waiwai moisturizing.
ʻO ka oxygen oxide - he mea waiwai o ka inorganic origin, aia i loaʻa ka hao a me ka oxygen. Aia ma kahi ʻāpana "Rosuvastatin" ua hoʻohana ʻia he dye.
Ka loaʻa ʻana o ka Titanium dioxide (hiki i nā mea like ke loaʻa: titanium oxide IV, titanium keʻokeʻo) - ka ʻoni ʻana me ka meaʻai me ka hōʻailona ʻana E
E hoʻomaʻemaʻe ʻia.

No ke aha e pono ai ʻoe e ʻike e pili ana i nā kikoʻī o "Rosuvastatin"

ʻO ka hiki ke kūʻai i ka lāʻau lapaʻau ma ke kumukūʻai maikaʻi loa. ʻO ka pinepine, ʻo ka uku o nā analogues he uku haʻahaʻa. ʻAʻole pili kēia i ke ʻano o ka huahana, akā paha ma muli o ka liʻiliʻi o ka hoʻolaha, ke halihali a me nā uku e ae. Eia kekahi, nā hihia o ka hui ʻana o ka mālama ʻana i nā loea i nā mea lapaʻau a me nā mea lapaʻau paha me nā ʻoihana lāʻau lapaʻau a i ʻole nā mea ʻole kāmela mea ʻike ʻole, i ka wā hiki ke kākau ʻia i kahi kumu kūʻai mua loa a i ʻole nā analogue.
ʻO ka hiki ke hoʻololi i ka rosuvastatin i ka haʻalele ʻana o ka lāʻau lapaʻau mua i ka pākahu. I ka manawa pinepine, ʻaʻole hiki i ka mea lapaʻau ke haʻi aku i nā nīnūnika o ka lāʻau lapaʻau, a i ʻole e hoʻāʻo e kūʻai i nā kumukūʻai nui loa

ʻO ka papa inoa o nā huaʻōlelo o "Rosuvastatin"

ʻO ka inoa o ka lāʻau lapaʻau Mea hana Mea Hoʻohālike Distinctive hiʻona i ka hoʻohana ʻia, etc.

ʻOkaʻohana	ʻO ASTRAZENECA UK LTD (ʻAmelika Hui Pū ʻIa).	lactose monohidatula, mcc, kaʻai o ka magnesium, ka calcium o ka hydrogen phosphate, ka iron oxide, hypromellose, titanium dioxide, crospovidone	hele
Akorta	PJSC Pharmstandard-Tomskkhimfarm (ka Lūkini Russian)	he like ia me ka "Crestor"	hele
Mertenil	Gedeon Richter (Hania)	he like ia me ka "Crestor"	nā papa me ka dosage maʻamau i kī ʻia ʻia he 0.2 mg ʻoi aʻe o ka rosuvastatin no kēlā me 5 mg, ʻo ia ka: nā papa o 5 mg - ka ʻike maoli o ka rosuvastatin he 5.2 mg, ma nā papa o 10 mg - 10.4 mg a pēlā aku.
Rosart	Wehewehe ʻavlelo (Islande)	he like ia me ka "Crestor"
Rosistark	Belupo (Kroasia)	Hoʻohana ka quinoline melemele ma mua o nā mea hao ʻoi aku, like nā mea like
Rosuvastatin Kalima	Hoʻokomo ʻo MSN Laboratories Limited (India), Assia Chemical Industries Ltd (Israel) a me nā mea ʻē aʻe	hele	ʻaʻole ke kūʻai ʻia o ka lāʻau lapaʻau ma o nā kumu kūʻai kūʻai mai nā hale kūʻai, ʻo ia ka mea kūʻai liʻiliʻi loa ma ka 5 kg.
Canu Rosuvastatin	Hoʻouka Nonprofit Hoʻonui ʻana	ma kahi o ka oxide iron, ua hoʻohana ka alumia varnish a hoʻohui ʻia ka selecoate ʻulaʻula, ua like nā ʻano like ʻole e like me ka hoʻolālā maʻamau	i kahi nui o nā loiloi maikaʻi
Rosuvastatin-SZ	ʻOihana hoʻonohonoho "North Star"	Hoʻololi ʻia ka hao kalika ma ka varnish alumini no ʻekolu mau ʻano	hele
Rosucard	Zentiva (Czech Republic)	Ua hoʻohuli nā croscarmellose i ka hypromellose mai ka helehelena mua, ua like nā mea like
Rosulip	EGIS Pharmaceuticals PLC (Hāloli)	kūlike me ka hoʻoili kumu
Roxer	KRKA (Slovenia)	ua hoʻohui ʻia nā copolymers o butyl methacrylate a me methyl methacrylate i ka ua
Kauoha	"TEVA Pharmaceutical Industries, Ltd" (Israel)	ʻO ka hui pū me ka varnish alumina a me ka wai melemele lā i ka melemele, nā mea i koe o nā mea i kū like me ka pūlohi kumu (me ka hao ʻoid ka hā)

ʻO nā lāʻau āpau o luna o ka lālani nā mea hoʻohālike e pili ana i ka rosuvastatin, ʻo ia hoʻi nā lāʻau me nā mea ikaika like. I ka ʻoiaʻiʻo, hana āpau - like ia ka lāʻau like me nā inoa kūʻokoʻa like ʻole a kūʻai ʻia ma nā wahi kūʻai a me nā kumukūʻai kūʻai like ʻole (e hāʻawi ʻia ke kumukūʻai kūʻai awelika ma ka papa i ka ʻaoʻao e hiki mai ana o ka hoʻolaha). Aia kekahi hui kūlohelohe kūʻokoʻa, ʻo ia hoʻi, nā lāʻau lapaʻau mai kekahi hui lāʻau lapaʻau (ma kēia hihia, reductase inhibitors), kahi like ka hopena, akā mau ʻokoʻa like. ʻO kēia mau lāʻau i nā huaʻōlelo kūlohelohe a hiki ke kuhikuhi wale ʻia e ka poʻe e hele nei i ka loiloi ma ka kumu o ka ʻike makana.

ʻO ka papa hoʻohālikelike o ke kumukūʻai o nā kikowaena o "Rosuvastatin"

Akorta	Kumukūʻai: 530 rubles
Mertenil	Kūʻai: 500 rubles
Rosart	Kumukūʻai: 485 mau rubles
Rosistark	Kūʻai: 450 mau rubles
Canu Rosuvastatin	Kūʻai: 420 mau rubles
Rosuvastatin-SZ	Kūʻai: 450 mau rubles
Rosucard	Kumukūʻai: 590 mau rubles
Rosulip	Kumukūʻai: 515 rubles
Roxer	Kumukūʻai: 540 rubles
Kauoha	Kumukūʻai: 480 mau rubles

No ka like o ke aʻo ʻana, i hana wale ʻia ma ka manaʻo o nā mea hoʻohana o nā lāʻau lapaʻau e nīnau ʻia nei, aia ka papa inoa ma luna nei i nā analogues i loko o kēia kaha a me nā helu: 10 mg o rosuvastatin i kēlā me kēia papa, 30 papa i hoʻokahi pā. ʻO kēia ʻano hoʻokala he mea kaulana loa i waena o nā mea kūʻai, no ka mea, e aʻo ʻia e hoʻomaka i ka lawelawe ʻana i ka lāʻau i loko o kēlā me kēia mahina e hiki ai ke hoʻoholo i ke kiʻekiʻe o ka hoʻohālikelike ʻana i ke kino o ke kanaka iā rosuvastatin.

ʻO ke kumu kūʻai o "Rosuvastatin" a me ka hiki ke hoʻololi me ia

I loko o ke kumukūʻai kūʻai olakino "Rosuvastatin" ma kahi o 10 mg a me ka helu o nā papa, 30 mau ʻāpana he kūʻai i loko o nā kumu kumukūʻai mai 380 a 490 mau rubles, e pili ana i ke kumu kūʻai kumu kūʻai a me ka mea kūʻai aku o nā huahana lāʻau, a me ka mea e pili ana i ka ʻāina.

No laila, i ka hapanui o nā hihia, ʻoi aku ka mea kūʻai mua loa ma ka Rosuvastatin ma mua o kona mau kikowaena, a ua pono ke kūʻai aku i ka analogue wale nō inā ʻaʻole i loaʻa ka lāʻau lapaʻau maoli ma kēia kīkeke.

Ma muli o nā loiloi i hoʻopili ʻia ma ka ʻatikala o ka lehulehu ma ka Pūnaewele a ma ka paʻi nūpepa, hiki ke hoʻoholo ʻia no ka makemake o ka poʻe kūʻai aku i ka lāʻau mua.

Loaʻa kahi hewa i loko o ka kikokikona? Koho ia a kaomi Ctrl + Kākaua e hoʻoponopono mākou iā ia!

Nā papa 5 mg, 10 mg, 20 mg a me 40 mg Rosuvastatin: nā ʻōlelo aʻoaʻo, nā loiloi a me nā kumukūʻai

I kēia ʻatikala lāʻau lapaʻau, hiki iā ʻoe ke kamaʻilio me ka lāʻau lapaʻau Rosuvastatin. E wehewehe aku i nā ʻōkuhi no ka hoʻohana ʻana i ka mea e hiki ke lawe ʻia ai nā papa hoʻonaninani, nā mea kōkua a ke lāʻau lapaʻau, nā hōʻailona pehea e hoʻohana ai, contraindications a me nā hopena ʻaoʻao. Hāʻawi ka hōʻike makahiki i ke ʻano o ka lāʻau lapaʻau a me kāna ʻano.

I loko o kaʻatikala, hiki i nā kauka a me nā mea kūʻai ke waiho wale i nā loiloi maoli e pili ana iā Rosuvastatin, kahi āu e ʻike ai inā ua kōkua ka lāʻau lapaʻau i ka mālama ʻana i ka hypercholesterolemia a me ka hoʻohaʻahaʻa ʻana i ke kolamu koko i nā pākeke a me nā keiki, no ka mea i kuhikuhi mau ʻia. Ka papa kuhikuhi i nā ʻōlelo aʻoaʻo o Rosuvastatin, nā kumukūʻai o ka lāʻau lapaʻau i loko o nā lāʻau lapaʻau, ʻo ia hoʻi i kona hoʻohana ʻana i ka wā hāpai.

ʻO ka lāʻau lipid-hoʻokuʻu i ka rosuvastatin. Hōʻike nā ʻōlelo no ka hoʻohana ʻana i nā papa o 5 mg, 10 mg, 20 mg a me 40 mg haʻahaʻa haʻahaʻa koko, ua kuhikuhi ʻia lākou no ka mālama ʻana i ka hypercholesterolemia, me ka pale ʻana o ka atherosclerosis.

E hoʻokuʻu i ke ʻano a me ka ʻano

Hoʻohana ʻia ka lāʻau lapaʻau Rosuvastatin i ke ʻano o nā papa, papa ʻaina ʻoniʻoni no ka hoʻokele waha (waha).

He ʻulaʻula kukui a i ʻole paha i ka kala kala, nā ʻāpana a me ke ʻano biconvex.

ʻO ka mea hana nui o ka lāʻau lapaʻau ka rosuvastatin, kona mea i loko o ka 1 papa he 5, 10, 20 a 40 mg.Pēlā pū kekahi o kāna palapala kikoʻī

Hoʻopili ʻia nā papa Rosuvastatin i nā pūʻulu blister o 10 mau ʻāpana. Aia ka pahu kīlea he 3 a 6 mau pūʻulu blister a me nā kauoha no ka hoʻohana ʻana i ka lāʻau lapaʻau.

Nā hopena hopena

E kūʻē i ke kua mua ʻana o ka lawe ʻana i nā papa Rosuvastatin, hiki ke hoʻomohala ʻia ka hopena o ke ʻano kino o nā kino a me nā ʻōnaehana:

Nā kumuhana pākēneka - kahi wikiwiki i ka ʻili, kona puʻu, ʻūlū, e like me ka puhi ʻupena.
ʻO ka ʻōnaehana o ka hanu - he lohi i ka constipation, nausea, hōʻeha i loko o ka ʻōpū, emi pinepine ka hoʻowalewale o ka pancreas (pancreatitis) i ulu.
Pūnaehana urinary - ʻike pinepine ʻia ka protein (proteinuria) a me ke koko (hematuria) i loko o ka urine.
Pūnaehana Endocrine - ka hoʻomohala ʻana o ka maʻi diabetes type 2.
ʻŌnaehana musculoskeletal - ʻehaʻeha o ka naʻau (myalgia), nā mānoanoa (myositis) a me ka luku (rhabdomyolysis), ʻoi loa i ka poʻe me kahi predisposition i ka myopathy.
Pūnaehana wahī - ʻeha, hōʻeha, a nāwaliwali maʻamau (asthenia).

ʻO ka hoʻomohalaʻana i nā hopena ʻaoʻao he hōʻailona e hilinaʻi ana i ka dosis. Hoʻonui nui kā lākou pinepine me ka hoʻohana ʻana i ka lāʻau lapaʻau ma kahi maʻa o 40 mg i kēlā me kēia lā. ʻO ke hiʻohiʻona o nā hopena maikaʻiʻole ke kumu no ka hoʻoponopono hoʻoponopono ʻia a i ʻole ka haʻalele ʻana i ka lāʻau.

ʻO nā keiki, i ka wā hāpai a me ka lactation

Rosuvastatin ua contraindicated i ka wā hapai a ma ka wā hānai. Pono nā wahine o nā makahiki hānau hānau i nā ala kūpono o ka contraception. No ka mea he mea nui ka kolamu a me kāna mau huahana biosynthesis no ka hoʻomohala ʻana i ka maʻi fetal, ʻoi aʻe ka hopena o ka hōʻemi ʻana o ka HMG-CoA reductase i ka pono o ka hoʻohana ʻana i ka lāʻau lapaʻau i nā wahine hāpai.

I ka hihia o ka hapai i ka wā e mālama ai, pono e hoʻokuʻu koke i ka lāʻau. ʻAʻohe ʻākepili i ka hāʻawi ʻana o ka rosuvastatin me ka waiū umauma, no laila, i ka manawa o ka umauma, pono e hoʻokuʻu ʻia ka lāʻau.

Nā ʻōlelo kikoʻī

Ke hoʻohana nei i nā dosis kiʻekiʻe o ka rosuvastatin (maʻa mau 40 mg), hiki ke nānā ʻia ka proteinuria tubular, he maʻamau ka mea maʻamau. ʻAʻole hōʻike kēia mau kuhi i ka exacerbation / holomua o ka maʻi ʻelima.

Hoʻomaopopo ka poʻe maʻi e lawe ana i ka nui loa o ke ʻano o ka lāʻau e nānā i ka hana ʻoi. No ka hoʻokaʻawale ʻana i nā hopena o ka hopena, ʻaʻohe mea e kuhi ʻia e hoʻoholo ai i ka hana o ka phosphokinase creatine ma hope o ka hoʻoikaika kino o ke kino kino a i ke alo paha o nā kumu ʻē aʻe no ka hoʻonui i kāna hana.

Inā ma ka hoʻomaka ʻana o ka ho'ōla, ua hana nui ʻia ka hana mua o ka phosphokinase creatine (ʻoi aku ʻo 5 mau manawa), ma hope o nā lā 5-7, e hana ʻia kahi lua. Ke hōʻoia nei i nā hōʻailona, ʻaʻole hoʻomaka ka mālama ʻana. ʻO ka hoʻomaka koke ʻana o ka ʻehaʻeha o ka hōʻeha ʻana a me ka nāwaliwali o ka hōʻeha ʻana, me ka hoʻohui pū ʻana me ke maʻi a me ka malaise, pono ka mālama ʻana i ka lāʻau lapaʻau.

I kēlā mau hihia, pono e hoʻoholo i ka hana o nā mea koho phosphokinase. Inā haʻalele nā hōʻailona, a hoʻi hou nā mākaukau, hiki iā ʻoe ke noʻonoʻo hou i ke kau hou ʻana o Rosuvastatin ma nā haʻahaʻa haʻahaʻa ma lalo o ka mākaʻikaʻi ʻana o ke kūlana o ka mea maʻi. Ke hana ʻole nei i nā hōʻailona, hiki ʻole ka nānā ʻana o ka mālama ʻana i ka hana o ka phosphokinase.

Aia ka hōʻike ʻana i nā hihia i loaʻa pinepine ʻole o ka pale ʻana i ka meopathy paʻa o nā hanana i hoʻomaka ʻia me nā hōʻike pilikino (hoʻomanawanui i ka nāwaliwali o ka palupalu a me ka nui o nā hana serum creatine phosphokinase) i ka wā o ka hopena a i ka wā e pani ʻole ai ʻo Rosuvastatin. Eia kekahi, noiʻi serological, hōʻike ʻana i nā ʻōnaehana a me nā ʻōnaehana, a me ka hoʻohana ʻana i nā lāʻau immunosuppressive e pono ai.

Ke lawe nei i ka Rosuvastatin a me ka hopena concomitant, ʻaʻole ʻike ʻia nā hōʻailona o ka nui o ka hopena ma ka ʻāeʻe huila.

Eia naʻe, aia kekahi mau manaʻo e pili ana i ka hoʻonui ʻana o ka myopathy a me myositis i nā poʻe maʻi e lawe ana i nā HMG-CoA reductase inhibitors i hui pū me nā fibric acid derivatives, me ka komo pū

me nā gemfibrozil, cyclosporine, acid acid nikotinic i nā lipid e hoʻohaʻahaʻa i nā wai (ʻoi aku ka nui ma mua o 1000 mg i kēlā me kēia lā), nā mānoanoa antifungal azole, nā inhibitor HIV protease a me nā antibiotics macrolide.

Inā ma ka poʻe maʻi ke hoʻomohala ʻia ka ʻōhumu o ka glucose ma ka 5.6–6.9 mmol / L, ua hoʻonui ʻia ka nui o ka maʻi mellitus type 2. Hōʻike ʻia ka hōʻemi ʻana / hoʻoneʻe i ka lapaʻau i nā hihia i loaʻa ai ka hana o nā transaminases hepatic i loko o ka serum koko ma mua o ka palena o ka maʻamau ma o 3 mau manawa a keu paha.

Inā he kānalua i ka hoʻomohala ʻana o ka maʻi māla interstitial (hōʻike ʻia me ka pōkole o ka hanu, ka wīwī waiwai ʻole, nāwaliwali, ke kaumaha ʻana o ke kau, ka maʻi a me ka hana maikaʻi), ua hoʻopau ʻia ʻo Rosuvastatin.

Ma muli o ka hiki ʻana o ka hoʻomohala ʻana a me ka dizziness, pono e nānā nā mea maʻi i ka wā e mālama ai i ka kaʻa.

Hoʻohui nūhou

Hiki ke lawe ʻia nā anacids ma hope o kekahi manawa (ma kahi o 2 mau hola) ma hope o ka lawe ʻana i kēia lāʻau lapaʻau, ʻoiai ua hoʻohana kā lākou hoʻohana ʻana i kahi kaohi o ka neʻe o Rosuvastatin.

ʻAʻole pono hoʻi e lawe ʻia ʻo Erythromycin i ka pilina me ka lāʻau lapaʻau, ʻoiai ua hoʻemi ʻia ka hopena o ka lawe ʻana i nā lāʻau lapaʻau.

40 mg rosuvastatin i ka manawa like me nā fibrates i contraindicated. Hoʻonui ka Gemfibrozil i ka loaʻa o ka myopathy i ka wā i hoʻohana pū ʻia me kekahi mau HMG-CoA reductase inhibitors (hui pū ʻole ʻia). Ke hui pū nei me nā fibrates a i ʻole lipid-hoʻohiolo ʻana i ka wai o ka acid nicotinic, pono e noʻonoʻo pono ka nui.

Nā hōʻike o ka lāʻau Rosuvastatin

E hoʻoholo ke ana i ke kumuhana:

Kauoha
Akorta.
Rosuvastatin Kalima.
Rosart.
Rosistark.
Rosuvastatin SZ.
ʻOkaʻohana.
Rosucard.
Rosulip.
Roxer.
Mertenil.
Suvardio.
Canu Rosuvastatin.
ʻĀpana.

Hoʻokomo pū ʻia nā pūʻulu statins:

Leskol.
Pravastatin.
Tulip.
Rovacor.
Roxer.
Simvastol.
Cardiostatin.
Ator.
Kauka.
Rosucard.
Lovasterol.
Leskol forte.
Lipostat.
Atherostat.
Zokor forte.
Lovacor.
Simvalimite.
Akorta.
Lipobay.
ʻĀpana.
Kauka.
ʻVorlelo ʻohu.
Rosulip.
ʻĀpelatin.
Atorvox.
Rosart.
Torvacard.
Liprimar.
Lovastatin.
ʻOkaʻohana.
Actalipid.
ʻĀlelo Simgal.
Simlo.
Kauoha
Hōʻuluʻulu.
Zorstat.
ʻO Simvacol.
Vasilip.
Aries
Simvastatin.
Mertenil.
Kāleka.
Zokor.
Atorvastatin.
Anvistat.
Hana ʻia.
Hoʻokahi.
Lipona.
Sinkard.
Novostat.
Torvalip.
ʻO Holetar.
Mevacor.
Atomax

ʻO nā hua'ōlelo hoʻomaha a me ke kumukūʻai

ʻO ke kumukūʻai kumukūʻai o Rosuvastatin (10 mg papa no 30) i Moscow he 325 mau rubles. Hoʻokuʻu ʻia e ka papa lāʻau.

ʻO 2 mau makahiki mai ka lā i hana ai ka ola o ka papa o nā papa. E mālama ʻia ka lāʻau lapaʻau i loko o kāna pūpū waiwai ʻana, i kahi wahi maloʻo maloʻo ma kahi pālua o ka ea ʻaʻole ʻoi aʻe ma mua o +25 C. E mālama pono ʻole i nā keiki.

ʻO kahi loiloi hōkeo o nā mea kaulana kaulana a me ka uku hoʻi o ka lāʻau lapaʻau "Rosuvastatin"

ʻO Rosuvastatin kekahi o nā lāʻau lapaʻau lipid-ka haʻahaʻa a me ka hoʻohana nui. Inā no kekahi mau kumu, no ka laʻana, ʻo ka nele o kahi kīhāpai a i ʻole ke kumukūʻai koʻikoʻi, ʻaʻole hiki i ka mea maʻi ke kūʻai i ka lāʻau lapaʻau mua, a laila hiki ke hoʻololi ʻia me kahi alapi e like me ke ʻano, he nui nā Rosuvastatin.

ʻO ka ʻike nui e pili ana i ka lāʻau lapaʻau a me nā kuhikuhi i ka hoʻohana

Rosuvastatin (Rosuvastatin) - Eia kēia lāʻau lapaʻau lipid-kaila o ka hanauna o ka makahiki IV hou (hou) mai kahi pūʻulu farmacological nui o nā statins, nā mea ikaika i nā mea kanu o nā inoa rosuvastatin i ke ʻano o ka paʻakai paʻakai (kalepona rosuvastatin).

Pono ʻia kēia lāʻau lapaʻau no ka hoʻoponopono ʻana i ka cholesterol kiʻekiʻe mau (hypercholesterolemia), ʻaʻole hiki ke mālama ʻia me nā ʻano lāʻau ʻole.Ua kuhikuhi ʻia nō ia ma ke ʻano o ka hōʻiliʻili paʻakikī o nā ʻano maʻi ʻē aʻe o ka hanu o ka ʻaihue (dyslipidemia), no ka pale ʻana o nā hōʻeha cardiovascular a me ka wehe ʻana o nā hoʻololi atherosclerotic ma nā paia o nā moku koko.

Hoʻokumu ka hana o nā statins i ka pale ʻana i ka hoʻoneʻe o ka enzyme, nona ke kuleana no ka hoʻokumu ʻana o ka kolamu ma ka ate (he kumu no kahi 80% o ka waiwai).

Nā hana hana i ka hana Hoʻopili ʻo Rosuvastatin i ka pani ʻana i ka enzyme - HMG-CoA reductase, ʻo ia ka "progenitor" o ke ʻano o ka endogenous synthesis (Chol, cholesterol) ma ka puʻuwai. Ma muli o kēia, hoʻonui ka nui o nā mea i hoʻokae i ka lipoproteins haʻahaʻa haʻahaʻa, ka mea e hoʻowalewale i ke kaʻina o kā lākou maluhia a me ka excretion mai ke kino.

ʻO kahi hopena, e pili ana i ke kāwili o ka hoʻohana o ka lāʻau lapaʻau, ke emi nei ka nui o ka neʻe ʻana o ka "bad" kolesterol (LDL, LDL), a me ke pae o ka "maikaʻi" kolamu (HDL, HDL) i ke koko me ka hoʻonui hou aʻe i ka uku uku.

Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa kiʻi ʻoniʻoni, pono e hoʻopau ʻia wale nō i loko (orally), me ka liʻiliʻi o 100-150 ml wai, i kēlā me kēia manawa o ke ao, ʻaʻohe o ka meaʻai.

ʻO ka hui kumu o Rosuvastatin e loaʻa ana i ka waiu waiu (lactose) monohala, ka mea i hiki ai i ka lāʻau lapaʻau ke hiki ke loaʻa i nā mea maʻi me ka hoʻomehana kū hoʻokahi o kēia māhele a me nā poʻe me ka nele o ka lactase.

Huaʻa noho hoʻoponopono Koho ia ʻo Rosuvastatin e ke kauka i ke kū hoʻokahi, e pili ana i ka paʻakikī i kēlā me kēia hihia. Hoʻomaka ka hoʻomakaʻana me ka maʻa liʻiliʻi (5-10 mg hoʻokahi manawa i ka lā) a hoʻonui e like me ka mea e pono ai (hāʻawi ʻia ʻole nā hopena lāʻau).

Hiki ke ʻike ʻia ka hopena lipid-kahe ʻana ma hope o 7-9 mau lā ma hope o ka hoʻomaka ʻana o ka hoʻomaʻamaʻa ʻana, a ma hope o 2 hebedoma he hiki i ka 90-100% o ka hopena hiki loa i mālama ʻia ma nā papa holoʻokoʻa o ka hana maʻamau o Rosuvastatin.

ʻOi aku ka maikaʻi o nā mea hana?

Ua hoʻomohala ʻia ka lāʻau lapaʻau mua ʻo Rosuvastatin e ka hui ʻo Japanese i ka ʻo Shionogi & Co. (Shionogi & Co), eia nō naʻe, ke hoʻopili ʻia nei nā analogues ma lalo o ka inoa non-proprietary international (INN) e nā hui lāʻau lapaʻau hou:

Lūkia - Lōkana (Phstandard), Ozone (Ozon), Canonfarma (Kanonfarma), FI Obolenskoye (OBL Pākaʻaka),
haole - Astra Zeneca (Astra Zeneca), Gideon Richter (Gedeon Richter), Actavis (Actavis), Belupo (Belupo).

Kūpono kēia mau hui āpau i nā generics, i.e., kope kope i ka mea ola, ʻo ka mea hana i hana ʻia ka rosuvastatin like ʻole, akā ʻokoʻa lākou i ka hoʻokumu mua ʻana e ka laina ʻenehana hana o ka hana, inoa inoa a me ka hoʻohalike o nā mea hoʻohiki.

No ka mea like like me nā kikoʻī pololei like i ka mea mua, mai ka manaʻo mai o kona kūpono, ʻaʻole ia e manaʻo i ka ʻoihana e hāʻawi i ka makemake i ka wā e kūʻai aku ai, akā aia ke kūʻai ʻia ʻo Rosuvastatin no ka manawa lōʻihi, ʻo ia ke ʻano e noʻonoʻo pono ai i nā lāʻau ʻinike mea kūʻai aku.

ʻO nā mea waiwai kaulana a me nā hili no rosuvastatin

Ma mua o ka noʻonoʻo ʻana i nā mea kikoʻī a me nā mea pili no Rosuvastatin, pono e hoʻomaopopo ʻia, ʻoiai ke koho ʻia he kauka, ʻae i ka mea maʻi ke koho i nā ʻano kuʻuna kūpono, e kālele ana i kāna makemake iho, ka peke a me ka hoʻomākeʻakeʻe pilikino i nā mea hoʻohui ʻē aʻe i ka ʻano. ʻO ka mea nui ke hoʻokō me ka ʻōlelo a me ka regimen e hōʻike ana i ka lāʻau.

He pākuʻi ikaika ʻo Roxera, e ʻae ʻia ka rosuvastatin e hoʻokuʻu wale ʻia i loko o ka ʻōpū liʻiliʻi, kahi e hoʻokomo ai nā papa i ka loli ʻole, a i ʻole ia i ka hopena luku ʻia o ka wai ʻōpū.

Nā hiʻohiʻona o ka manaʻona: Hoʻonui a butyl methacrylate a me methyl methacrylate copolymers i ka ua.

ʻOihana hana: KRKA, Slovenia.

Nā kumukūʻai lāʻau: mai 383 RUB / 30 pcs 5 mg a 1617 mau rubles / 90 pcs. 20 mg i kēlā me kēia.

Hōʻike ʻia ʻo Rosucard (Rozucard) i ka bioavailability maikaʻi (ma mua o 20%), akā ʻo ka mea ikaika ma ka rosuvastatin e hana maʻalahi ia mai ke kino, a no laila ua loaʻa ka hopena i ka hopena therapeutic.

Nā hiʻohiʻona o ka manaʻona: i ʻole o ka hypromellose mai ka hoʻopuka mua ʻana, ua hoʻohana ʻia ka croscarmellose e like me ka pauku palaoa.

ʻOihana hana: Zentiva, pae Repubalika.

Nā kumukūʻai lāʻau: mai 613 kahaki. / 30 pcs. 10 mg kēlā me kēia i ka 2708 rub./90 pcs. 40 mg pākahi.

Kaukaʻi nā kauka

E hoʻohaʻahaʻa pono i ka cholesterol a pale i ka atherosclerosis me nā hoʻopiʻi ʻaoʻao, hōʻike nā mea loea i ka choledol. Nā lāʻau lapaʻau hou:

ka mea i pili i ka amaranth i hoʻohanaʻia i ka mālama ʻana i ka maʻi cardiovascular,
hoʻonui i ka hana o ka kolamu "maikaʻi", hoʻemi i ka hana o "kino" i ke kino,
ka hoʻohaʻahaʻa nui ʻana i ka hōʻeha o ka hōʻeha ʻana a me ka puʻuwai,
hoʻomaka ka hana ma hope o 10 mau minuke, ʻike ʻia kahi hopena koʻikoʻi ma hope o nā hebedoma 3-4.

Hōʻoiaʻiʻo ʻia ka hoʻomaʻamaʻa ʻana e ka hoʻomaʻamaʻa lāʻau a me ka noiʻi ʻana o ka Institute Institute of Therapy.

ʻO Mertenil (Mertenil) kahi kiʻekiʻe i ka hoʻomaʻemaʻeʻana o ka mea ikaika. Mālama kēia i ka maikaʻi o ka lāʻau i ka liʻiliʻi me nā hopena liʻiliʻi, ʻo ia ka mea nui i ka wā e lawe ai i ka rosuvastatin i nā maʻi maʻi.

Nā hiʻohiʻona o ka manaʻona: pili i nā mea mua, koe wale nō nā mea i hoʻohana ʻia no ka pena ʻana i ka pōpoki.

ʻOihana hana: Gedeon Richter, Hanau.

Nā kumukūʻai i nā lāʻau lapaʻau: mai 478 kahalaha. / 30 pcs. 5 mg a 1439 mau rubles / 30 pcs. 40 mg pākahi.

ʻO Rosulip (Rosulip) kahi mea hoʻohālike haʻahaʻa o Rosuvastatin, he mau bioavailability kiʻekiʻe a hōʻiliʻili mālie, kahi e hiki ai iā ʻoe ke hana liʻiliʻi i ka hopena therapeutic i makemake ʻia o ka mea ikaika ma ke kino.

Nā hiʻohiʻona o ka manaʻona: kū i ka rosuvastatin ʻaʻole i ke ʻano o ka calcium, akā ma ke ʻano o ka paʻakai paʻakai (rosuvastatin zinc).

ʻOihana hana: EGIS (EGIS Pharmaceuticals PLC), Honu.

Nā kumukūʻai lāʻau: mai 469 RUB / 28 pcs 5 mg a 1087 mau rubles / 28 pcs. 20 mg i kēlā me kēia.

Crestor (Crestor) - hoʻokahi wale nō o ka lāʻau lapaʻau i hoʻokumu ʻia ma ka rosuvastatin. Hōʻike ʻia kēia lāʻau lapaʻau e ka hoʻonaʻauao kiʻekiʻe me ka hoʻoili o ka mea hana a, inā hilinaʻi ʻoe i ka ʻōlelo hoʻomanawanui, ʻoi aku ka maikaʻi, akā i ke kumukūʻai ʻoi aku ka maikaʻi ma mua o nā mea hoʻonā'ē aʻe.

Nā hiʻohiʻona o ka manaʻona: Kūlike nā mea a pau i ke ʻano kumu mua.

ʻOihana hana: Astra Zeneca, Ke Aupuni o ka United Kingdom.

Nā kumukūʻai i nā lāʻau lapaʻau: mai 1756 kahū. / 28 pcs. 5 mg kēlā me kēia no 5036 rub./28 mau pcs. 40 mg pākahi.

ʻO Tevastor kekahi o nā moʻoʻoniʻoni maikaʻi loa o Rosuvastatin, no ka mea, e hoʻopili koke ana i loko o ke kino, e kau ana i kahi hopena therapeutic i haʻi ʻia, a ma ka manawa like ʻoi aku ka uku ma mua o ka lāʻau lapaʻau mua.

Nā hiʻohiʻona o ka manaʻona: aneane like me ka lenten e like me ka mua (koe wale ke dye).

ʻOihana hana: TEVA (TEVA Pharmaceutical Industries Ltd), ʻIseraʻela.

Nā kumukūʻai lāʻau: mai 341 kahakaha. / 30 pcs. 5 mg a 1522 mau rubles / 90 pcs. 20 mg i kēlā me kēia.

Rosuvastatin-SZ

Rosuvastatin-SZ (Rosuvastatin-SZ) - i kēia lā ʻo ia ke hoʻololi pono loa no Rosuvastatin mai kahi mea hana Rusia. ʻOiai ke kumukūʻai haʻahaʻa loa, ʻaʻole ia i haʻahaʻa ma mua o ka mea i nā huahana ʻē aʻe a he waiwai nō hoʻi ia i ka waiwai.

Nā hiʻohiʻona o ka manaʻona: oxide ironide e hoʻohana ʻia ma kahi ʻano i kahi manu i hoʻololi ʻia e ka alumini varnish o ʻekolu mau ʻano ʻokoʻa.

ʻOihana hana: FC Severnaya Zvezda ZAO, Rusia

Nā kumukūʻai lāʻau: mai 178 kahaki. / 30pcs. 5 mg a 684 mau rubles / 30 pcs. 40 mg pākahi.

Hoʻohui i nā statins, aia kekahi ala ʻē aʻe. Koi aku ka poʻe heluhelu ʻO ka hoʻōla kūlohelohe, kahi i hui pū me ka meaʻai a me nā hana, hoʻemi nui ʻia ka kolamu ma hope o 3-4 pule. ʻO ka manaʻo o nā kauka >>

Loaʻa iā Rosart (Rosart) nā pono āpau i ka lāʻau lapaʻau mua a loaʻa pinepine kahi hopena maikaʻiʻole i ke kino, no ka mea ua hoʻomaʻemaʻe pono ʻia nā mea ikaika a me nā mea kōkua. Hiki iā mākou ke ʻōlelo, ʻo ia ka mea pono pinepine loa no ka rosuvastatin.

Nā hiʻohiʻona o ka manaʻona: Ua like nā mea a pau me ka hoʻomākaukau i ka mākaukau mua.

ʻOihana hana: Actavis Group, Kahiki

Nā kumukūʻai i nā lāʻau lapaʻau: mai 426 RUB / 30 pcs 5 mg a 2347 rub./90 pcs. 40 mg pākahi.
ʻO nā huahana e hoʻohaʻahaʻa i ka kolamu a hoʻomaʻemaʻe i nā moku koko.

ʻO nā lāʻau lapaʻau maikaʻi loa pau loa no ke kolamu kiʻekiʻe ma ke ʻano o nā papa.

Pehea e hoʻohana ai i ka lāʻau lapaʻau Rosuvastatin Canon?

ʻO Canu Rosuvastatin, hana ʻia e Canonfarm Production CJSC, kahi ala kūpono e hoʻohaʻahaʻa i nā triglycerides a me ka cholesterol.

Pehea e lawe ai

Ma mua o ka hoʻohana pono ʻana, ua contraindicated ka papa e ʻalā, ua lawe ʻia, holo ʻia me ka wai maʻemaʻe wale nō. Koho ʻia ka dosage e ke kauka komo ʻana, me ka noʻonoʻo i ka pono o nā ala ʻē aʻe o ka hoʻōla ʻana, pane ʻana i ka lāʻau, pali lipid, ka hopena o ke kūkulu ʻana i nā ʻōkuhi o ka ʻōnaehana cardiovascular.

ʻO ka papa ʻōlelo hoʻomaka ʻia he 10 mg hoʻokahi i ka lā. ʻO ka hoʻonui ʻia o nā maʻa inā i hōʻike ʻia ke ʻae ʻia ma hope o 4 wiki o ka lawe ʻana i ka lāʻau lapaʻau. Ma hope o ka hoʻonui ʻana i kēia pane, pono kahi nānā e nānā i ke kiʻekiʻe o nā lipids.

ʻO nā hopena ʻaoʻao o ka canon rosuvastatin

Ke lawe nei i ka lāʻau lapaʻau e hiki ke hōʻeha i ka maʻi, ʻuwelu, constipation a i ʻole ka maʻi ʻana, ka ʻāmaika e like me ka maʻi. I nā pilikia pinepine, hoʻomohala i ka mea maʻi i ka hoʻomanaʻo ʻana, hepatitis, pōkole o ka hanu, hōʻeha.

ʻO ke ʻano o ka ʻōnaehana musculoskeletal i ka mea ikaika e hoʻomohala ai i ka hanana myopathy, arthralgia, myalgia, rhabdomyolysis me ka maikaʻi ʻole o ka hana ʻole. ʻO nā hopena ʻē aʻe o ka lāʻau lapaʻau ka nui o:

ʻAno maʻi type 2.
Proteinuria
Hōʻikeʻike
ʻO nā wahi hiamoe hiamoe, insomnia.
Hoʻopau i nā libido.

Me ka hoʻomohala ʻana o ka pane maikaʻi ʻole mai ka ʻōnaehana paleola, maʻi ʻeha, urticaria, a me Quincke edema.

ʻO ka hopena o ka lāʻau hoʻonāukiuki i kahi loli o nā ʻāpana laboratorium, me ka hana o ka transaminases hepatic, he nui o ka glucose, nā hormone thyroid a me bilirubin.

Hoʻohana i ka wā hāpai a me ka lactation

ʻO nā pōmaikaʻi i manaʻo ʻia mai ka lawe ʻana i ka lāʻau lapaʻau e ʻoi loa i ka pōʻino i hana ʻia i ka ʻōpū, no laila ua contraindicated ka lāʻau i ka wā e hāpai ana. ʻAʻohe ʻikepili i ka palekana o ka lāʻau i ka wā lactation, e koi ai i ka hōʻole ʻana i ka hoʻolaʻa ʻana a i ka hoʻihoʻi ʻana i ke keiki i ka hānai manuahi i ka wā mālama.

Nā Hōʻike Hoʻomaʻi

Roma, 43 makahiki, Moscow

Ua kuhikuhi ʻia ka lāʻau lapaʻau e hōʻemi i ka hopena o ka hoʻouka ʻana o ka naʻau. No nā mahina ʻeono, ua hoʻololi nā ʻōmike kolesterol no ka mea maikaʻi aʻe. Inu wau i nā papa e like me nā ʻōlelo a pau o ka cardiologist.

ʻO nā ʻōlelo no ka hoʻohana ʻana i ka papa inoa inoa lōʻihi o ka hopena o ka hopena, aia ka nui o nā loiloi maikaʻi ʻole ma ka Pūnaewele, no ka mea, ua hoʻomaka wau e inu i kēia mau palaki.

Akā ʻaʻole i puka mai nā hopena makemake ʻole, a kiʻekiʻe ke hopena.

Olena Alekovna, 51 makahiki, Kiev

Ua hoʻomaka ʻia ka mālama ʻana me Dibikor, ma hope o ke ʻano nui, inā he koʻikoʻi ka piʻi ʻana o ka triglycerides, pono pono e hoʻomaka wau e inu i kēia lāʻau lapaʻau. Ua manaʻo ʻia ka hopena, akā ua kūʻai aku ka loaʻa. Ua kū ʻia nā hopena ʻaoʻao. Ma hope o kahi hoʻomaha paʻa, ua wae ʻia ʻo Dibicor.

Maikaʻi ka lāʻau lapaʻau, akā he hopena maikaʻi ia i ka hoʻowalewale, hoʻonāukiuki i ka hiʻohiʻona o nā mākele pōkole, nā hōʻeha. Pono wau e mālama ʻia a hoʻomanawanui i nā hopena maikaʻi ʻole, a e nānā wale nō i kahi ala e pakele ai iā lākou.

Nā palapala helu a me ka hoʻopihapiha o statin

I loko o ke keʻena lāʻau lapaʻau, kūʻai ʻia ʻo Rosuvastatin i ke ʻano o nā papa convex pōkā i loko o kahi kiʻi ʻoniʻoni ulaula, i manaʻo ʻia no ka lawelawe waha (loko).

ʻO ka mea nui o ka lāʻau lapaʻau ka rosuvastatin, ka paʻa ʻana o rosuvastatin i loko o ka papa i hilinaʻi ʻia i ke ʻano o ka hoʻokuʻu: 5.10 a 20 paha i ka 1 ʻāpana.Hoʻopili ʻia ʻo Statin me nā mea kōkua: hypromellose, starch, titanium dioxide, crospovidone, microcrystalline cellulose, silicon dioxide, dye carmine, triacetin, silicon dioxide, magnesium stearate.

Hoʻopaʻa ʻia ka lāʻau lapaʻau i loko o kahi pā kuhi me 10 mau pākahi. I loko o kahi pahu kāleka aia paha 3 a 6 paha o ia mau papa, i hoʻohui ʻia e nā ʻōlelo kuhikuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau.

Nā hiʻohiʻona Pharmacological

ʻO ka hana ikaika o ka lāʻau lapaʻau he hopena lipid-lowing. Hoʻopili ʻo Rosuvastatin i ka hoʻoneʻe ʻana i ka huina HMG-CoA reductase, kuleana no ka hana ʻana o ka mevalonate - ka mea o mua o ka cholesterol. He hopena pololei ka mea hana i nā hepatocytes (nā pona o ka ate), nona ke kuleana o kā lākou kolamu (endogenous).
I ka hoʻonui ʻana i ka nui o nā receptors lipoprotein haʻahaʻa ma ke alo o nā hepatocides, hoʻōla ia i ka hoʻopau ʻana o ka nui o ka kolamu mai ka kaʻai a puni, e kōkua ai i ka hōʻemi ʻana i ka hana o VLDL, no ka mea he lipoproteins me kahi haʻahaʻa haʻahaʻa haʻahaʻa i hana nui loa i ka pili koko.

ʻO kahi ʻokoʻa nui ma waena o Rosuvastatin a me nā statins ʻē aʻe, ʻaʻole ia e hakakā me ka kolokola "maikaʻi ʻole", akā e pani pū i ke ahulau aʻeha loa, e like me nā kumu ʻepekema nui ke kumu nui o ka atherosclerosis.

Hoʻonui ka lāʻau lapaʻau i ka synthesis o nā nitrogen, ka mea i hāʻawi i ka hoʻomaha i nā moku koko, a hana i ka hopena i kapa ʻia ka pleiotropic (hoʻohui).

Ma hope o ka hoʻohana ʻana i statin, hoʻāla koke ka mea hoʻonaninani, akā naʻe ke komo ʻole ʻana i ka ʻōnaehana ka puni, ua kahele ʻia ʻia ma luna o nā ʻili o ke kino. Hoʻomoʻalo iki i ka lohi ma mua o kona mau hoa a me ka wā o ka hoʻopauʻana ʻoi aku ka lōʻihi.

Ka ʻike nui ʻana i ka plasma kiʻekiʻe loa o ke ʻano ikaika. ʻOiai no ka mea i kauoha ʻia ai ka lāʻau i loko o kahi liʻiliʻi ma mua o nā mea hoʻohālikelike, ʻae aku ka lāʻau lapaʻau i ka rosuvastatin e pili pū me nā lāʻau ʻē aʻe e hoʻohālikelike ʻia i nā statins o nā hanauna ʻē aʻe. Eia naʻe, ʻaʻole ia e hoʻopakele iā ia mai nā hopena hopena.

ʻAʻole like me ka hapanui o nā statins, ʻo ka lāʻau ka aneane ʻaʻole i hoʻohālikelike i ka papalū: 5% excrete the kidney, and most (90%) haʻalele ia i ka ʻawa i kona ʻano kumu.

Kūʻai a me nā contraindications

No nā papa rosuvastatin, ʻo nā ʻōlelo i hoʻohana no ka hoʻohana ʻana i kahi papa inoa o nā contraindications a me nā palena:

Ke hoʻomau nei i kekahi o nā ʻano o ka ʻano hoʻohālikelike,
ʻO ka manawa o ka hapai a me ka lactation, ka nele o nā contraceptives kūpono i ka wā ulu, ʻaʻole ia e ʻae i ke kāpae i kahi manaʻo paʻa i hoʻolālā ʻia i ka wā o ka mālama ʻana me rosuvatin,
Nā makahiki o nā keiki (a hiki i ka 18 mau makahiki), me ka ʻokoʻa o nā wā'ōpiopio me ka hypercholesterolemia hoʻoilina,
ʻO ka huehue o ka puʻukū huehue ma muli o ka heʻe ʻana o kāna hana i ka hihia o ka hepatocytes me kahi kiʻekiʻe o ka plasma kiʻekiʻe o nā transaminases hepatic (enzymes),
Hoʻohana pinepine ʻia ʻo cyclosporine,
ʻO Myopathy (kahi maʻi o nā uaua striated o ka ʻōpū) a i ʻole ʻano ke kūkulu iā ia.

ʻO ka hoʻohanaʻana i ka lāʻau lapaʻau ma ka palena (40 g) i kahi nui he mau contraindications hou aʻe:

Ka maʻi waʻeha
ʻO nā kūlana e hoʻonāukiuki i ka hoʻonui ʻana o ke kaila o ka rosuvastatin,
Hoʻopuka i myopathy,
Nā lawai pūlima
ʻO Myotoxicity i ka mālamaʻana i nā lāʻau'ē aʻe e pale ana i ka hoʻoneʻe ʻana o ka huina HMG-CoA.
ʻO ka nānā ʻana me ka fibrates.

ʻAʻole kuhikuhi ʻia ka nui loa i ke kanaka no ka lāhui Mongoloid. Pono kēia mau mea e hoʻolilo i ka kumu no ka mālama ʻana o ka statin i kahi ʻokoʻa ʻē aʻe. Ma mua o ka kuhikuhi ʻana iā Rosuvastatin, pono e pono ke kauka e kūpono loa, no laila he mea nui e hōʻike iā ia e pili ana i nā lāʻau āpau, nā mea hoʻolako i ka mea kanu, mea kanu lāʻau i kēia manawa e lawe ʻia.

Rosuvastatin: nā ʻōlelo e hoʻohana ʻia ai

Pono ka ʻawaʻawa me ka wai i nā manawa āpau. ʻAʻole make ka ʻai i kāna hana, akā no ka mea ʻo ia i hana pinepine ʻia ka cholesterol i ka pō, ʻōlelo pinepine ka lāʻau lapaʻau no ke ahiahi, hoʻohana hoʻokahi.

Inā hoʻohana ʻia nā statins no ka manawa mua, ʻaʻole ma mua o 5-10 mg / lā i kuhikuhi ʻia. i kekahi. I ka hana haʻahaʻa e pāpālua ʻia ka nui o ka lāʻau lapaʻau ma 20 mg / lā. ʻO ke ʻano maʻamau no kēlā me kēia lā (40 g) i kuhikuhi wale ʻia no ka hypercholesterolemia koʻikoʻi, ʻoiai ke piʻi pinepine ka hopena o nā ʻaoʻao.

Me ka hopena o ka renal a i ʻole hepatic function impairment, kahi iʻike ʻia i nā myopathy, nā ʻelele o ke ʻano Mongoloid, ʻoi aku ka nui o ka hopena i ʻōlelo ʻia ma mua o 5 g. ʻO ka manawa lōʻihi o ka papa hoʻokolokolo ua hoʻoholo ʻia e ke kauka, akā hiki ke hoʻoponopono ʻia nā hoʻoponopono ʻia ʻokoʻa ma mua o hoʻokahi mahina ma hope aku.

ʻO ka hopena ʻike mua ʻia e ʻike ʻia ma hope o hoʻokahi pule, ma hope o ʻelua mau lāʻau i ke alapine ʻia ma 90%. Ke piha ikaika, hōʻike ʻo Rosuvastatin iā ia iho i ke kolu o ke wiki o ka hoʻokomo pinepine ʻana. I ka wā e hiki mai ana, mālama ʻia ka hopena i loaʻa.

ʻAʻole i lawe ʻia ka lāʻau lapaʻau i nā papa papaʻa, ua ʻōlelo ʻia nā statins no ke ola, me ka hoʻoponopono ʻia ʻana inā he pono. Ma waho o kaʻai ʻole a me ka mālama ʻana i ke olakino pilikino, maikaʻi ʻole ka mālama ʻana i ka lāʻau lapaʻau. Pehea e hoʻohaʻahaʻa i ka cholesterol i nā ala kūponoʻole, e nānā i ke wikiō

Nā hopena hopena

E kū'ē i ke ʻano o ka mālama ʻana o statin, hiki ke hoʻomohala ʻia ka hopena kūlike mai nā kino he nui:

ʻO ke kuʻi Gastrointestinal - ke kī pinepine ʻana o ka maʻi dyspeptic, hoʻololi i ka ulana o ka neʻe ʻana i ke alo o ke alo, i kekahi manawa i ʻaī ʻia ka pancreas,
CNS - nāwaliwali ākea, nā poʻo, nā lūlū āpau.
Pūnaehana endocrine - type 2 diabetes mellitus (DM),
Nā huaka genitourinary - proteinuria a me hematuria,
ʻO ka musculoskeletal system - myasitis, myalgia, rhabdomyolysis (ʻo ka luku ʻana o ka naʻau me ka hoʻokumu ʻana o nā pūhui koʻikoʻi no nā keiki), he pōpilikia maoli me ka makemake o ka myopathy,
ʻĀpeku - hives, rashes, a me ka ʻeha o ka ʻili.

ʻO ka hopena e pili ana i nā mea i kūpaʻa ʻole ʻia. Ke mālama ʻia me ka rosuvastatin me kahi kikoʻī (40 mg / lā), hoʻonui ka nui o lākou. ʻO ke ʻano o ia mau ʻano kumu ke kumu no ka hoʻoponopono ʻana i ka hoʻoponopono a i ʻole ka loli ʻana o ka lāʻau lapaʻau.

Nā manaʻo loea

Ke koho nei i ka rosuvastatin, mālama ke kauka i nā ʻōlelo kūikawā:

Hoʻomaopopo ka lōʻihi o ka mālama ʻana me ka statin, a ma nā kīhāpai kiʻekiʻe, e nānā pinepine ʻia ka ʻike plasma o ka ʻimi KFK enzim (creatine phosphokinase) i mea e pale ai i nā maʻi o ka ʻōnaehana o ka muscular, a me ka makemake o ka myopathy.
Hoʻohālikelike ka hoʻohana ʻana i nā lāʻau lapaʻau e pale i ka hoʻoneʻe o ka hoʻoneʻe HMG-CoA e pono ai kahi hana akahele a me ka nānā ʻana i ka mālama olakino i ke ʻano o ka mea maʻi.
Ma mua o ka lawe ʻana i nā statins, pono e ʻike ʻia ka mea maʻi e pili ana i nā hopena maikaʻi ʻole o ka ʻōpū, no laila ʻo ke ʻeha ʻehaʻeha e lilo i kumu no ka kipa ʻana i kahi kauka.
E kūʻē i ka hope o ke hoʻohana ʻana iā Rozuvatsatin, ua hoʻopaʻa ʻia nā hihia o kēlā me kēia myasthenia (nāwaliwali o ka mānoina), i hoʻonā ʻia e ka synthesis o ke ʻano kumu o ke ʻano o nā autoantibodies.
Me ka hoʻoponopono o ka maʻi, a me kēlā me kēia wiki he 2-4, e nānā ʻia ka puna o ka plasma me nā lipids.
Ma mua o ka hoʻomaka ʻana i ke papa a hoʻi hou, ma hope o kekahi mau pule, pono kahi hana noiʻi o ka hana pono o ka ate.
Hiki i Rosuvastatin ke hana i ka lāʻau lapaʻau, me ka lawe ʻana iā lākou, pono ʻoe e hōʻaha i ke kauka ma mua o ka hāpai ʻana i kahi hoʻoponopono lapaʻau.
No ka mea, ʻo ka hoʻomākaukau e pili ana i ka lactose, no ka mau hewa i ka hoʻopili ʻana o nā huapalapala i ka huehue lau (lactase deficiency, glucose-galactose malabsorption), pono e mālama pono i kēia hiʻohiʻona.
Hoʻololi ʻo Statin i ka hoʻopili ʻana o ka glucose, ka piʻi ʻana o ka neʻe o ka plasma e kōkua i ke ʻano o ke ʻano maʻi diabetes type 2, he mea kūpono ke nānā pono ʻana i nā ʻōnaehana.
ʻAʻole ka ʻike e pili ana i ka hopena o ka rosuvastatin i ka nānāʻana i ka noʻonoʻo, hana o ka lolo, a me ka hopena o ka hopena.

I loko o nā lāʻauʻaiʻai, hoʻokuʻu ʻia ka lāʻau lapaʻau i mua o ke kauka a ke kauka, hiki ke mālama ʻia me ka mālama ʻana me nā statins.

Nā hopena o ka hoʻopili ʻana me nā lāʻau lapaʻau ʻē aʻe

I ka manawa e lawe pū ʻia me nā lāʻau ʻē aʻe, hiki ke hoʻololi i ka waiwai o ka statin a i kēia mau lāʻau lapaʻau, no laila e pono ke ʻike ke kauka a noʻonoʻo i nā nuances āpau.

ʻO ka pilina me nā derivatives acid nicotinic e hoʻonui i ka nui o ka hiki ʻana o ka maʻi a me ka rhabdomyolysis.
Hoʻopili ka pilina me nā diuretics i ka hopena o ka hōʻemi o ka hoʻoneʻe ʻana o nā hormones steroid.
Hoʻohana pinepine i ka statin me nā lipine haʻahaʻa-hoʻohaʻahaʻa i ka hopena o nā hopena o nā ʻano like ʻole.
ʻO ka hui pū ʻana me ka glycosides cardiac e hoʻonui i nā ʻike digoxin.
Hiki i ka immunosuppressants i hui pū me ka rosuvastatin ke hoʻopilikia i ka hoʻomohala ʻana i nā ala o nā renal a me rhabdomyolysis.
Hoʻopili i nā pilina me nā anticoagulants ka hopena o ke koko.
ʻO nā lāʻau antifungal i ka hoʻopili e hoʻonui i ka hōʻeha o ka renal dysfunction a me rhabdomyolysis.
ʻO ka hakakā ʻana o ka ʻōpū hiki ke hoʻonui i ka maʻi o ka puʻuwai.

Kōkua me ka overdose

Me ka hoʻohana like ʻana o nā papa he nui i ka nui o ia mau lā, ʻaʻole i ʻike ʻia nā hōʻailona o ka overdose, ʻoiai ke mau nei ka pharmacokinetics o ke ʻano ikaika o ka lāʻau ma ka pae mua.

Hiki i ka overdose koʻikoʻi ke hoʻonui i nā hōʻailona o nā hopena o ka ʻaoʻao e hoʻomaʻamaʻa i ka lavage gastrointestinal, ka hoʻohana ʻana i nā ʻōpū o ka ʻōpū, a me nā ʻano maʻi hōʻailona.

ʻAʻole loaʻa kahi ʻano antidote kūikawā no ka rosuvastatin.

Nā lāʻau lapaʻau like

Ua ʻike ʻia ʻo Rosuvastatin ma ke kūʻai lāʻau lapaʻau mai 2003. Wahi a ka hopena therapeutic a me ka hoʻokumuʻana no

ʻO nā mea hoʻohālike Rosuvastatin i kēia lā:

Manuela Sz
Mertenil
Kauoha
Roxer
Kanoha Rosuvastatin,
Rosicore
Rosulip,
Kēlā
Kalima,
Rosart,
Akorta,
Rosucard
Torvacard.

Wahi a ke kumukūʻai o ka mālama ʻana, hiki ke hōʻhele ʻia kēia hui i nā māhele 3: ka helu kālā nui loa: Rosuvastatin Canon, Rosuvastatin SZ, Akorta (250-650 rubles), kumukūʻai kumukūʻai: Rosart, Mertenil, Tevastor, Roxer, Rosucard, Rosulip (400-900 rubles) , aloha: Crestor (1100-2200 rub.). No nā analogue rosuvatin, ua lawe ʻia kahi loiloi kumukūʻai no nā pahu me nā papa he 10 mg.

Ka helu ʻana i ka hoʻohanaʻana

E pili ana iā Rosuastatin, ua piha nā loiloi i nā hopohopo e pili ana i ka hiki ʻana o nā hopena hopena, akā hiki ʻole ke kapa ʻia iā lākou. ʻO ka hapa nui o nā hoʻopiʻi (allergies, nā ʻōpū, nā ʻeha ʻeha) ʻaʻole ia e ka Rosuvastatin kumu, akā, e nā mea maʻalahi e like me nā mea hou i hana ʻia ma India a me nā ʻāina o ka Soviet Union mua. Hāʻawi nā kauka iā Krestor a i ʻole nā mea kiʻekiʻe kiʻekiʻe e hana ʻia ma Eastern Europe.

Hiki ke loaʻa nā hopena o nā noi multicenter o ka honua holoʻokoʻa o ROSU-PAZ ma Rosuvastatin ma ke wikiō

Kuhi ʻia ʻo Rosuvastatin e kaohi i ka atherosclerosis. Me ka hana maʻamau o ka pauna lipid, ka hopena o ka ʻāʻī ʻana o ka puʻuwai, hōʻemi ʻia ke kaʻe, ʻaʻohe pono e hana i ka hoʻokaho a me ka hala ʻana o ka coronary surgery, a hoʻomaikaʻi i ka neʻe ʻana o ke koko i nā wāwae e nā ʻoihana hana.

ʻO ka hoʻokūkū nui ma kēia lā ma waena o ka hanauna hou o statins. Ua loaʻa ka hopena o Rosuvastatin i ka cholesterol, akā i ka noʻonoʻo ʻana i nā hopena ʻona, ʻoi aku ka maikaʻi o ke kuhikuhi ʻana i nā mea hou aku.

ʻO ka lawe ʻana i kahi lāʻau lapaʻau ikaika hiki ke hoʻopiha wale i ka hoʻololi ʻana i nā kūlana hou o ke ola, ʻaʻole ia e hoʻololi i ka pono o ka meaʻai a me ka hana kino.

Hōʻike nā kauka i nā kauka

Elena Alekseevna, cardiologist, Moscow

ʻO ka lāʻau lapaʻau ka mea maʻamau i ka lāʻau lapaʻau Pelekania, akā maikaʻi loa. Inā ʻoe e hahai i kahi meaʻai a me ke ʻano kūpono i koho ʻia, ʻaʻole i ulu liʻiliʻi nā hopena a me nā ʻōmaʻomaʻo.I ka manawa like, ʻo ka uku o ka lāʻau e waiho pono ana no ka hapa nui o nā maʻi.

Tatyana Valerievna, phlebologist, Samara

I ka hapa nui o nā hihia, ʻaʻole nā hopena varicose ka hopena o nā mea hoʻoluhi maikaʻi ʻole o ka ʻōnaehana cardiovascular. No ka hoʻonui i ka ulu o ka lāʻau lapaʻau, pono paha e hoʻohaʻahaʻa i ka kolu o ka cholesterol, ka mea e hōʻoia ai i ka hoʻohana ʻana i nā statins, akā pono ia e hoʻomaopopo i ka mea maʻi e hahai i nā ʻōlelo aʻoaʻo a pau e pili ana i ka meaʻai, ka manawa o ka lāʻau lapaʻau a me ka uku.

ʻO ka hoʻopili ʻana o kēia mau papa i kahi papa lapaʻau e pono ai i nā hihia koʻikoʻi a ma hope wale nō o ke kūkākūkā ʻana me kahi cardiologist a me ke koho ʻana i kahi meaʻai kūpono. Hāʻawi ka lāʻau lapa i kahi hopena kiʻekiʻe a kūmau.

9 a me nā mea haʻahaʻa kūpono i nā Rosuvastatin

Nā ʻāpana ʻōpala
Nā hiʻohiʻona o ka lāʻau

Ua hoʻākāka ʻia ka Rosuvastatin a me nā mea hoʻohui i nā kolamu ma ke koko ma mua o ka maʻamau. Aia ka lāʻau lapaʻau i nā papa o nā statins o nā mau heʻehā (4 mau hanauna). Hoʻohālikelike ʻia me nā lāʻau lapaʻau ʻē aʻe i kēia hui, ʻo rosuvastatin kahi hana ʻoi aku ka palekana a palekana.

Ua hana ʻia synthetically a hōʻike i nā waiwai hydrophilic, ma muli o ke kī ʻole i ka hopena ʻino i ka pʻā.

Hoʻololi maikaʻi nā lāʻau i ka hana ʻana o nā lipoproteins haʻahaʻa haʻahaʻa, ʻo ia ka mea nui i hana ʻia ai ka cholesterol.

Eia kekahi, ʻo ka lawe ʻana i kēia lāʻau lapaʻau ʻaʻole ia e hoʻonā i nā pulupulu o nā palahalaha a me nā mea āpau ʻē aʻe mai ka ʻaoʻao o ka pono o ka ʻiʻo. Hōʻike ʻia ka hopena kūpono i hoʻokahi hebedoma ma hope o ka hoʻomaka ʻana o ka hoʻohana ʻana, a ma ka 4 heʻe lilo i lilo loa ia a me ka mālama maʻamau ka lōʻihi. ʻO kēia mau hiʻohiʻona e hana ai i ka rosuvastatin he lāʻau noiʻi nui no ka poʻe maʻi e pono ai e hoʻohaʻahaʻa i ka kolamu.

Nā ʻāpana ʻōpala

ʻO ka mea ikaika o ka lāʻau lapaʻau ka paʻakai kaleka o rosuvastatin. Eia kekahi, ʻo ka ʻōnaehana hoʻonohonoho ʻana i kekahi o nā mea hoʻohui, ʻo kēlā me kēia mea i ka hana:

ʻO cellulose Microcrystalline kahi mea maikaʻi loa e hoʻopili ʻia ana mai ke kino kanaka. I ka hoʻohuiʻana o nā lāʻau lapaʻau, hana ia i mea hoʻopiha a me kahi mea e lawelawe ai e hoʻopili i nā mea āpau.
Lawaʻawa Lactose. Hoʻohana e hoʻomaikaʻi i ka ʻono o ka lāʻau lapaʻau. Eia naʻe, hiki i kēia mea ʻenehana ke lawe i nā papa no nā poʻe e ʻeha nei me ka nānā ʻole i ka lactase.
Kalikoli Kalepa ʻO kēia kahi hui paʻakikī, kahi i loaʻa ka metallic calcium a me ka phosphoric acid. ʻO ke hoʻonohonoho ʻana o nā papa e kōkua i ka assimilation o ka hana koʻikoʻi koʻikoʻi.
ʻO ka lāʻau ʻo Magnesium. Mālama i ka papa hana papa ʻaina a lawelawe ia e like me kahi hoʻopiha piha no ka kino.
ʻO ka Hydroxypropyl methylcellulose kahi hoʻohui hoʻohui moisturizing kūikawā e pono no ke kaʻina hana o ka palapala hana.
ʻO Povidone e hana i ka ʻōpū e hoʻokaʻawale i nā mea ʻona i ka kino, me nā mea i kū ʻia ma ka hopena o ka hana a rosuvastatin.
ʻO Triacetin kahi kākoʻo meaʻai ʻāpono (E1518). Ma kahi ʻāpana o nā papa, he hana ia me ka plasticizer a me kahi moisturizer, kahi nui no ka kaʻina.
Pahu - ka mea hao hao a me ka titanium dioxide he mau mea hoʻohui palekana e hoʻomaikaʻi i ke ʻano o ka lāʻau lapaʻau.

ʻO nā papa Rosuvatatin, i hoʻohana ʻia no ka cholesterol ma luna o ka palaki, ua hua ʻia e nā hui lāʻau lapaʻau ma lalo o nā inoa like ʻole. ʻO nā āpau āpau he kikoʻī pololei, ʻo ia hoʻi, he ʻano like ko lākou mau ʻano.

ʻO ka lāʻau lapaʻau mua Krestor e hana ʻia mai e kahi ʻoihana Pelekane a loaʻa iā ia ka maikaʻi e like me ka lāʻau lapaʻau kiʻekiʻe maikaʻi loa. ʻO nā lāʻau āpau āpau kahi o ka pakanui ʻano mea rosuvastatin he generics.

ʻOkoʻa lākou i ka mea mua ma ke kumukūʻai a loaʻa paha kahi mea hoʻonaninani like ʻole o nā mea kōkua, ʻaʻole i ʻike nui i ko lākou hopena. Pono e noʻonoʻo i kēia wahi me ka hoʻonui nui ʻana i kekahi mau mea.