Kauka aʻoaʻo Aspikor - (Aspikor) no ka hoʻohana

ʻO ka lāʻau lapaʻau e pale ʻole i ka hana a ka enzyme cyclooxygenase 1 a me 2 (hoʻoponopono i ke kāpili ʻana o nā prostaglandins).

ʻO ka lāʻau Aspicor he analgesic (analgesia), nā hopena anti-inflammatory a me ka antipyretic.

ʻO ka mea hana waiwai acetylsalicylic e hoʻoheheʻe i ka hana o nā prostaglandins, ma lalo o ka mana o hipalgesia a me ka paulo. Hoʻopau i nā prostaglandins i ke kikowaena nuithermoregulation (ka hapa nui o E1) i hoʻoulu ai i ka hoʻonui ʻana, hoʻonui ʻia i ka lumen o nā kīʻaha koko o ka ʻili a ma muli o ke ʻano o ke kaohi ʻana o ke ʻano kino.

Loaʻa ka hopena analgesic e nā hana peripheral a me nā kikowaena o ka lāʻau lapaʻau. Hoʻopili ke aspicore i ka synthesis holomoana A2 ma loko o nā ʻāpana koko koko, hōʻemi ʻōpalaolapīpī hāpana a me kā lākou hoʻohui.

I ka poʻe maʻi me ka papa ʻole o ka angina, ʻo ka hoʻonaninua ʻo ka acetylsalicylic acid e hiki ke hoʻemi i ka make, ka hopena o ka ʻaila myocardial.

Hoʻomoe ka hopena antiplatelet ma kahi o hoʻokahi pule ma hope o ka lawe ʻana i hoʻokahi pāʻai.

ʻO kahi papa i kēlā me kēia lā he 6 mau a i ʻole ke hoʻonui i ka manawa prothrombin, pale i ke synthesis prothrombin i ka pepela pili.

Hoʻonui ka lāʻau lapaʻau Aspicore i ka nui o nā hoʻopiʻi hemorrhagic i ka wā o ka hōʻemi hōʻemi.

Ma lalo o ke kumu o ka lāʻau, hoʻonui ka excretion waawa uric (ma muli o ka haki ʻana o ka reabsorption tubular i loko o nā keiki.

Nā hōʻailona no ka hoʻohana ʻana

Ua kuhikuhi ʻia ʻo Aspicor no ka hoʻomaha ʻeha hōʻeha (nā ʻoluʻolu a me ke ʻano maʻalahi) o nā ʻano like ʻole: migraine, headache, myalgiamaʻi nā maʻi maʻi algodismenoreaaolaila lumbago, neuralgia, pepeha.

Hoʻohana ʻia ka lāʻau lapaʻau no ka febrile syndrome e pili ana i kahiʻano o ke kuʻuna o ka nāʻeha a me nā maʻi.

Nā Hoʻohui

ʻAʻole kuhikuhi ʻia nā papa aspicor no ʻiha diihoe hemorrhagic, me kahi ʻano kūlohelohe kū hoʻokahi i ka acetylsalicylic acid, me ka bronchial asthma, ke koko mai ka hoʻowalewale ʻana, me ka maʻi erosive a me nā ulcerative o ke ʻano o ka hoʻowalewale, nā manawa like o ka methotrexates, ke kahi o ka hapai ʻana (ka mua, kolu o ka hoʻomaʻamaʻa), nā keiki a me nā keiki a hiki i nā makahiki ʻumikumamālima.

Nā hopena hopena

Hiki i nā papa aspicor e hōʻeha i ka maʻi maʻi, nausea, nā pane kūlohelohe i nā ʻano o ka angioedema, ke ʻano ʻeha a me nā ʻili. Hōʻoiaʻiʻo bronchospasm.

E pale aku i ke kua o ke ʻano o ka mālama ʻana, hiki ke hoʻokau i ka hana o nā ʻili a me ka ʻōnaehana o ka aʻa ʻO ka maʻi a Reye (ka wikiwiki ka hana o ka hōʻaʻe o ka ate, ka dystrophy ate a me ka encephalopathy), ka leukopenia, thrombocytopeniaanemia kaumaha.

Hiki ke hāpai pū ʻia me ka lōʻihi o ka hana hypocoagulationeroses a me nā ulcerative lesi o ka digestive tract, dizziness, migraine, luaʻi, ʻike makaʻōheʻe,jade interstitialpehu, puhipuhi papillary, azotemia prerenal me ka hypercalcemia a me hypercreatininemia, ʻūhū, hoʻonui i nā hōʻailona o ka puʻuwai puʻuwai, aseptic meningitis, hoʻonui i nā ʻano o ka puhaka ʻālaʻi nephrotic.

Aspicor, mau ʻōlelo no ka hoʻohana ʻana (Ke ʻano a me ke ʻano)

Lawe ʻia nā papa aspicore i nā waha.

Me ka ʻeha, nā ʻōpū febrile lawe ʻia ka lāʻau lapaʻau a hilahila a hiki i 3 grama (ʻo ka pona i ʻōlelo ʻia ʻo 0.5-1 mau minamina i kēlā me kēia lā) no 3 mau puhē.

Ma ke ʻano he analgesic a me ka anti-inflammatory agent, hāʻawi ʻia ʻo Aspicor i kahi ʻano o 325 mg.

ʻAʻole pono ka lōʻihi o ka lōʻihi o ka hopena ma mua o nā hebedoma.

Pono e hoʻokaʻawale ʻia ka ʻano kūpono o ka lāʻau i ka 100-200 ml wai. ʻO ka nui o ka lāʻau lapaʻau ka 0.25-1 kalama (3-4 mau lā i ka lā).

Ke keu

I nā hihia koʻikoʻi o ka overdose, hypoglycemia, hyperventilation, coma, fever, ketoacidosis, nā puʻuwai a me nā hemahema hiki ke loaʻa.

ʻO ka hānai maʻi, hiki i ke hoʻohana ʻana i ke kumu ʻoihana hoʻāla, gastage lavage, diuresis, hemodialysis, a me nā hōʻailona maʻi e pono ai.

Hoʻohui

ʻAʻole ʻōlelo nā kuhikuhi no ka hoʻohana ʻana i ka Aspicore i ka hoʻohana ʻana i kahi lāʻau lapaʻau i ka manawa like me nā waha hypoglycemic agents, ka momona valproic, methotrexate, nā kāpena antiplatelet, thrombolytics,kūlohelohe anticoagulants, heparin, sulfonamides, antihypertensive a me nā mea uricosuric, diuretics.

Hoʻopilikia ka hopena hōʻeha o ka gastrointestinal me ka hoʻomohala i ka lāʻau me ka glucocorticosteroids a me nā lāʻau lapaʻau e pili ana i ka ethanol.

Hiki i ka Aspikor ke hoʻonui i ka kaomi o nā barbiturates, digoxin, lithium salts i loko o ka plasma.

Hoʻemi ka nui o ka waikawa acetylsalicylic i ka wā mālama antacids.

Hoʻonui ka hopena hematotoxic o Aspicore me ka mālama ʻana me nā lāʻau myelotoxic.

Nā ʻōlelo kikoʻī

Hoʻohana ʻia ka hoʻohana ʻana o Aspikor ma kahi lāʻau anti-inflammatory ma muli o ka pilikia nui o ka hoʻomohala ʻana i ka NSAIDs-gastropathy.

ʻAʻole pono nā lōʻihi o ka mālamaʻana ma mua o 5 mau lā.

I kēia manawa, ʻaʻole ke kauoha ʻia ka lāʻau lapaʻau no rōlani wahinehopia hopohopo form myocarditis, me ka ʻōmaʻomaʻo rheumatoid, a me ka pericarditis a me ka maʻi māloʻi.

Hoʻolakoʻo Aspicor e hoʻopau loa i nā lā 5-7 ma mua o ka hana i hoʻolālā ʻia.

Pono ke ʻano o ka mālama lōʻihi i ka nānā ʻana i nā helu koko, ka nānā ʻana o nā feces no ke koko okoa.

Hiki i ka lāʻau lapaʻau ke hoʻolako nā hopena teratogenic.

Hoʻopiliʻia ka Acetylsalicylic acid i ka umauma umauma.

Hiki i kahi lāʻau lapaʻau ke hoʻōla i kahi hōʻeha kūlike o ka maʻi gout.

E hoʻokuʻu i ka palapala, hoʻopili a me ka mea hoʻohui Aspicor ®

ʻO nā papa i uhi ʻia i ke keʻokeʻo a i ʻole hoʻi he keʻokeʻo, ʻona, biconvex, ma ka ʻāpana ʻāpana - he hui homogeneous o ke keʻokeʻo a i ʻole hoʻi he keʻokeʻo.

Nā mea kūʻai: cellulose microcrystalline, lactose monohidate, sodium croscarmellose, colloidal silicon dioxide (aerosil), waikawa stearic.

ʻO ka mana o ka palaki enteric: methacrylic acid-ethyl acrylate copolymer, propipylene glycol, macrogol 4000, titanium dioxide, talc.

10 kamepiula - nā kīpaha palemona (1) - nā ʻeke pepa.
10 kamepiula - nā ʻili uila (2) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.
10 kamepiula - nā papaki blister (6) - nā ʻeke pepa.
20 mau kāleka. - nā kīpaha palemona (1) - nā ʻeke pepa.

Ka hana lāʻau lapaʻau

Nā NSAIDs, ka ʻaina antiplatelet. Kahi ka hana o ka hana acetylsalicylic acid e kau ʻia ana ma ka hiki ʻole ke hoʻololi ʻia ʻana o ka cyclooxygenase-1 (COX-1), ma muli o ke ʻano he pahaka o ka thromboxane A 2 synthesis a me ke kaohi ʻana o ka ʻāpana platelet. Manaʻo ia ua hana ka acetylsalicylic acid i nā hana ʻē aʻe e pani ai i ka platelet aggregation, kahi e hoʻonui ai i kona papa i nā maʻi maʻi vascular.

Loaʻa ka Acetylsalicylic acid me kahi hopena anti-inflammatory, analgesic, antipyretic.

Lapaʻau lāʻau

Ma hope o ka lawelawe waha, ua hoʻopili ʻia ka acetylsalicylic acid mai loko mai o ka ʻāpana liʻiliʻi. Loaʻa ka C max i ka plasma i ka manawa maʻamau he 3 ma hope o ka manawa o ka inu.

Hoʻokomo ka Acetylsalicylic acid i kahi metabolial hapa i loko o ke ate me ka hoʻokumu ʻana o nā metabolites emi.

Hoʻopili ʻia ʻo ia e nā pōpoki, ʻelua hoʻololi a me nā metabolite. T 1/2 acetylsalicylic acid ma kahi o 15 mau minuke, no nā metabolites - e pili ana 3 hola

Nā ʻ Aslelo Aspikor ®

• ka pale ʻana o ka maʻi myocardial akala i mua o nā mea iʻike ʻia (no ka laʻana, ka maʻi mellitus maʻi, hyperlipidemia, hypertension arterial, huʻihui, ulaula, ʻelemakule),
• ka pale ʻana o ka hala ʻana i ka wā mikole,
• ka lani panghina,
• pale ʻana i ka huakaʻi (me i nā mea maʻi me ka maʻi cerebrovascular transient)
• ka pale ʻana o ka maʻi cerebrovascular transient,
• ka pale ʻana o ka thromboembolism ma hope o ka hoʻomaʻamaʻa ʻana a me ka hōʻiliʻili o ka vascular invasive (no ka laʻana, ka coronary artery bypass grafting, carotid artery endarterectomy, arteriovenous shunting, carotid artery angioplasty).
• ka pale ʻana o ka thrombosis vein hohonu a me ka thromboembolism o ka pulmonary artery me nā lālā ona (no ka laʻana, me ka lōʻihi o ka immobilization ma muli o ka hoʻopili nui o ka wehe ʻana).

Ka hoʻoponopono ʻia ʻana

Pono e lawe ʻia i nā papa liʻiliʻi, ma mua o ka papaʻaina, me nā nui o nā ʻano wai.

ʻO ka pale ʻana i ka infarction myocardial akala: 100-200 mg / lā (pono e ʻoka ʻia ka papa mua ma ka wikiwiki o ka komo ʻana).

ʻO ka mālamaʻana i ka infarction myocardial akene i mua o nā hopena pākuʻi: 100 mg / lā.

Kāohi i ka hoʻihoʻi pinepine o myocardial infarction, ka palena paʻa, ka pale ʻana o ka hōʻeha ʻana a me ka ulia cerebrovascular transient, pale ʻana i ka hoʻopiʻi thromboembolic ma hope o ke kauā ʻana a i ʻole nā ​​haʻawina invasive: 100-300 mg / lā.

Kāohi i ka thrombosis vein hohonu a me ka thromboembolism o ka pulmonary artery me kāna mau lālā: 100-200 mg / lā.

Kuhi ʻia ka lāʻau no ka hoʻohana lōʻihi. Hoʻoholo ʻia ka lōʻihi o ka hopena e ke kauka hele mai.

Loaʻa ka hopena

Mai ka pūnaehana ʻana: ka nausea, ka ʻōpio, ka luaʻi ʻana, ka ʻeha ma ka ʻōpū, nā ulia maʻi ulcerative o ka membous mucous o ka ʻōpū a me ka duodenum (e pili ana i ka perforated), ka maʻi gastrointestinal, hoʻonui i ka hana o nā enzymes ate.

Mai ka papa hana hanu: bronchospasm.

Mai ka ʻōnaehana hemopoietic: nui ka huhū, ʻokoʻa loa - anemia.

Mai ka ʻaoʻao o ka pūnaehana loko ma waena: nā dizziness, tinnitus.

Nā maʻi kūloko: urticaria, edema Quincke, pane anaphylactic.

ʻŌpū a me ka lactation

ʻO ka hoʻohana ʻana i ka salicylates i nā koina kiʻekiʻe i ka trimester mua o ka hāpai ʻia e pili pū me ka nui o ka piʻi ʻana o nā pūhaka hoʻomaʻamaʻa a ʻo nā keiki (split palate, defects heart). I ka lua o ka wā hapalua o ka hapai ʻana, hiki ke kuhikuhi ʻia nā salicylates me ka nānā wale ʻia o ka hōʻemi a me ka pono.

I loko o ke kolu o ka wā wana e hapai ai, ʻo ka salicylates i nā koina kiʻekiʻe (ʻoi aku ma mua o 300 mg / lā) e hoʻokaʻawale i ka hana, hana mua i ka ductus arteriosus i ka pūpū, hoʻonui nui ʻia ka huhū ma ka makuahine a me ka ʻōpio, a me ka hoʻokele ma mua o ka hānau ʻana e hiki ai ke hōʻeha i ka hemacen intracranial, aemaise i nā pēpē ma mua. ʻO ke koho ʻana o salicylates i ka trimester III o ka hapai ua contraindicated.

Hoʻokomo ʻia nā Salicylates a me kā lākou mau metabolite i nā mea liʻiliʻi i ka waiū umauma. Hōʻalo ka hoʻolilo ʻana o ka salicylates i ka wā lactation me ka hoʻomohala ʻia ʻana o nā hopena maikaʻiʻole i ke keiki ʻaʻole pono me ka hoʻomaʻamaʻa ʻana o ka ʻōpiopio. Akā, inā makemake ʻoe i ka hoʻohana lōʻihi ʻana i ka lāʻau lapaʻau a i ʻole ke koho ʻana i kahi palena kiʻekiʻe, pono e hoʻopau koke ʻia ka pale umauma.

Hoʻohui nūhou

Me ka hoʻohana pū ʻana o ka acetylsalicylic acid e hoʻonui ai i ka hana a nā huaʻōlelo penei:

• methotrexate ma ka hoʻohaʻahaʻa ʻana i ke kūleʻa a me ke neʻe ʻana mai ia i ka kamaʻilio ʻana me nā protein,
• heparin a indirect anticoagulants ma muli o ka hana platelet i ʻole a ka haʻalele ʻana o nā anticoagulants kūloko mai ka kamaʻilio ʻana me nā protein,
• nā hua lāʻau thrombolytic a me antiplatelet (ticlopidine),
• digoxin ma muli o ka emi ʻana o kāna hana renal,
• nā haole hypoglycemic (a me ka derivatives o ka sulfonylurea) ma muli o nā waiwai hypoglycemic o ka acetylsalicylic acid iho i nā kiʻekiʻe kiʻekiʻe a me ka neʻe mai o nā derogative sulfonylurea mai ke kamaʻilio pū me nā protein.
• valproic acid ma muli o kona kaawale ʻana mai ke kamaʻilio ʻana me nā protein.

Hoʻomaopopo kahi hopena hoʻohui i ka wā e lawe ana i ka acetylsalicylic acid me ka ethanol.

Hoʻopaliwali ka Acetylsalicylic acid i ka hopena o nā lāʻau uricosuric (benzbromarone) ma muli o ka hoʻokūkū tubular hoʻopau ʻana i ka waikika uric.

I ka hoʻonuiʻana i ka hoʻopauʻana o salicylates, hoʻonāwaliwali nā ʻōnaehana corticosteroids i ko lākou hopena.

VERTEX AO (Lūkia)