Noliprel A Fort > He hoʻomaʻemaʻe a me ke pale aku

Palani inoa: Noliprel A forte

ATX Code: C09BA04

ʻOihua wai: perindopril arginine (perindopril arginine) + indapamide (indapamide)

Mea Hana: Laboratories Servier Industry (France), Serdix, LLC (Russia)

Hoʻohou i ka wehewehe a me ke kiʻi: 11/27/2018

ʻO nā kumukūʻai i nā lāʻau lapaʻau: mai 564 mau rubles.

Noliprel A forte kahi hui antihypertensive hui pū, me ka angiotensin e hoʻohuli ana i ka enzyme inhibitor (ACE) a me kahi diuretic.

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa kiʻi ʻoniʻoni: oblong, keʻokeʻo (i loko o nā hue polypropylene me ka dispenser: 14 a 29 mau pcs., I loko o kahi pahu pahu me kahi mana mua o ka 1 haki, 30 pcs., I loko o kahi pahu pahu me kahi mana mua o ka wehe mua. 1 a i ʻole 3 mau pahu, i nā pahu no nā haukapila - 30 mau hue wai i loko o nā pahu pahu pahu, ma nā pahu pahu pepa 1 pallet a me nā kauoha no ka hoʻohana ʻana iā Noliprel A forte).

Pākaukau 1 papa:

nā mea ikaika: perindopril arginine - 5 mg (like me nā kiko o ka 3.395 mg perindopril), indapamide - 1.25 mg,
ʻO nā mea kōkua: lactose monohydrate, anhydrous colloidal silicon dioxide, maltodextrin, sodium carboxymethyl starch (type A), magnesium stearate,
Ke ʻano mea hana kiʻi kiʻi: premix no ka uhi ʻana o ke kiʻi keʻokeʻo SEPIFILM 37781 RBC hypromellose, macrogol 6000, glycerol, titanium dioxide (E171), magnesium stearate, macrogol 6000.

Keʻano "Noliprel forte": hoʻonohonoho a me ka hoʻokuʻu o ka hoʻokuʻu

Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa i pani ʻia me kahi kiʻi pale. Aia kēia lāʻau lapaʻa kekahi mau mea ikaika i ka manawa like, kahi e hāʻawi ai i kāna hopena hoʻohui. No ka kiko, kēlā me kēia papa pākahi i kēlā me 10 mg perindopril arginine (pili kēia kuina like me 6.79 mg perindopril) a me 2,5 ml indapamine.

I loko o ka hana ʻana i ka lāʻau, nā mea e like me ka magnesium stearate, colloidal anhydrous silicon dioxide, lactose monohydrate, maltodextrin, hypromellose, macrogol 6000, glycerol a me kekahi mau mea e hoʻohana ʻia he mau mea kōkua.

Pharmacological waiwai o ka lāʻau

ʻO kaʻoiaʻiʻo, ua pili pono nā waiwai o ka lāʻau "Noliprel forte" me ka hopena o ke kino o kāna mau lālā. Akā no nā mea hoʻomaka, he mea kūpono ʻole ke kī ʻia he hopena hypotensive ka lāʻau lapaʻau, a pākuʻi ʻia i nā systolic a me ka diastolic pressure. Ma muli o ka nui o ka hopena o kēia hopena. ʻAʻohe mau hopena i makemake ʻia ma mua o hoʻokahi mahina ma hope o ka hoʻomaka ʻana o ka mālama ʻana.

ʻO Perindopril kekahi o nā mea nui o ka lāʻau lapaʻau. ʻO kēia mea he mea pale o kekahi ʻano o ka enzyme. Hoʻopau i nā ipu koko a hoʻihoʻi i ke ʻano o ko lākou mau pā. Ua hōʻike ʻia nā haʻawina lehulehu he perindropril i hōʻemi ʻia i ke koko, a ʻo ka hoʻihoʻi ʻana i nā lāʻau, ʻaʻole ia i kahi kaho kuʻi. ʻO kekahi mea ikaika e hana ai, ʻo indapamide, like nō ia me kona mau waiwai i ka diuret thiazide. Mālama kēia māhele i ka lawe ʻana o nā paʻakai pālolo i ka nephron, ke alakaʻi nei i ka hoʻonui ʻia o ka diuresis a me ka hoʻopau ʻana o nā wai paʻakai me ka waiʻai.

Hoʻopau ʻia ʻo Perindopril i loko o ka puki. ʻIke ʻia kona kiʻekiʻe nui loa i nā hola 3-4 ma hope o ka hoʻokele ʻana. E like me ka indapamide, hoʻomaka ia e hana ikaika ma hope o hoʻokahi hola, a excreted me ka urine a me nā feces.

Lapaʻau lāʻau

ʻO Noliprel A forte kahi lāʻau hypotensive, ka hopena o ka mea ma muli o nā waiwai antihypertensive o perindopril a me indapamide, hoʻonui ʻia ma muli o kā lākou hui pū ʻana.

ʻO Perindopril kahi mea hoʻoneʻe ACE e pili ana i ka hoʻololi ʻana o ka angiotensin I i kahi o ka vasoconstrictor vaʻa nui o kaiotensin II. Eia kekahi, hoʻololi ʻo ACE (a kininase II) i ka bradykinin i loko o kahi heptapeptide hāpua. Loaʻa iā Bradykinin i loko o ke kino kahi hopena vasodilating. Aʻo kahi hopena o ka ACE, ua hoʻoneʻe ka hiʻu ʻana o ka ald testosterone, ua hoʻomaka ke kaʻina hōʻike pane maikaʻi, e hoʻonui ana i ka hana renin i ka plasma koko. Ma muli o ka preload haʻahaʻa a ma hope o ka ukana, hoʻonui ʻia ka hana myocardial. Hoʻohana lōʻihi ka hoʻohana ʻana i perindopril i ka hōʻemi o ka huakaʻi pale kolo peripheral (OPSS), kahi nui ma muli o kona hopena i nā kīʻaha ma nā puʻuwai a me nā puʻuwai. Loaʻa nā hopena i ka hoʻomakeʻa ʻole o ka sodium a me nā wai waiʻai a i ʻole ka hoʻomohala ʻana i ka tachycardia reflex.

Ua hoʻokumu ʻia ma ka hihia o ka hāʻule ʻole o ka puʻuwai naʻau (CHF), hāʻawi ka perindopril i ka emi ʻana o ka hoʻopiha ʻana i ka hoʻokahe ma ka ʻaoʻao hema a me ka ʻūlū ʻana o ka puʻuwai, kahi hōʻemi o ka puʻuwai, ka nui o ka hopena o ka puʻuwai a me ka hoʻonui i ka kaila koko peripheral.

ʻO Indapamide kahi sulfonamide ka mea like me nā mea kanu lapaʻau e like me ka diuret thiazide. Mālama i ka reabsorption o ka paʻakai sodium i ka māhele cortical o ka loop Henle, e hoʻonui ana i ka hoʻonui ʻana o ka klorida, sodium, a me kahi liʻiliʻi o ka magnesium a me nā paʻakai pālolo ma o nā keiki. Hoʻonui kēia i nā diuresis a hoʻoemi ʻia ka piʻi ʻana o ke koko (BP).

ʻO ka hopena antihypertensive o Noliprel A forte he hilinaʻi ma ke kūlohelohe, ʻoiai e kū ana a moe ana e hōʻike like ana ia e pili ana i ka diastolic a me ke ʻano koko systolic. Ma hope o ka lawe ʻana i ka pōkole, hoʻomau ka hopena o ka lāʻau no 24 mau hola. Loaʻa ka hopena therapeutic i ka palekana ma hope o 30 mau lā o ka mālama ʻana.

ʻAʻole hele pū ka haʻalele ʻana o ka maʻi maʻi.

Me ka hoʻohana ʻana o Noliprel A forte, ke emi nei ka nui o ka OPSS, kahi i hoʻohaʻahaʻa i ka pae o ka hypertrophy hema o ventricular (GTL), a me ka hoʻomaikaʻi ʻana i ka elasticity o nā ʻāpana. ʻAʻole pili ka lāʻau i ka metabolism o nā lipids a me ka kikoo o ka kolamu piha, kolamu, lipoprotein kiʻekiʻe (HDL) a me nā lipoprotein haʻahaʻa haʻahaʻa (LDL) a i ʻole triglycerides.

Me ka haole hypertension a me GTL, ma ka hopena o ka hui ʻana o perindopril a me ka indapamide, he nui ka nui o ka hōʻemi ma ka hema o ventricular mass index (LVMI) a me ka hopena antihypertensive e nānā pono ʻia me ka enalapril.

Ua hōʻike ʻia kahi haʻawina o ka hopena o Noliprel A Forte i ka hoʻopiʻi nui o ka macro- a me nā hoʻopiʻi mikrovascular i nā maʻi me nā maʻi diabetes type 2 e lawe ʻia ma ke ʻano he ʻelua no ka mālama maʻi glycemic a me ka hoʻolālā kūʻokoʻa glycemic control (IHC) (target HbA_1c emi ma mua o 6.5%). Ua hui pū kekahi hui o nā mea maʻi i ka noiʻi, ʻo nā hōʻailona maʻamau o ia mau makahiki: ʻo 66 mau makahiki, ke kahe koko - 145/81 mm Hg, ka nui o nā kaupaona momona - 28 kg no 1 m 2 o ka ili kino o ka kino, HbA1c (hemoglobin glycosylated) - 7.5%. ʻO ka hapa nui o nā poʻe maʻi ma ka maʻi hypoglycemic and concomitant therapy (e komo pū ana me antihypertensive, hypolipidemic, antiplatelet agents).

ʻO nā hopena noiʻi (ʻo ka lōʻihi o ke nānā ʻana ma kahi o 5 mau makahiki) i hōʻike ʻia he 10% i ka hopena o ka hopena o ka hopena i hui pū ʻia o ka hoʻopiʻi ʻana o ka macro- a me nā hoʻopiʻi microvascular i ka hui ʻo IHC (ka ʻokoʻa HbA_1c 6,5%) hoʻohālikelike me ka hui pū hoʻonohonoho maʻamau (medium HbA_1c 7,3%).

ʻO ka hōʻemi nui ʻana i ka hopena pili i lawe ʻia i ka hōʻemi o 14% i ka hoʻopiʻi ʻana i ka hoʻopiʻi nui o ka microvascular, 21% no ka hanana a me ka holomua ʻana o ka nephropathy, 9% no microalbuminuria, 30% no ka macroalbuminuria, a me 11% no ka hoʻomohala ʻana i ka hoʻopiʻi o nā keiki.

ʻAʻole pili nā mea pono o ka terapi antihypertensive e pili ana i nā pono i loaʻa i ka IHC.

Hoʻokumu ʻia ka hana antihypertensive o perindopril no ka mālama ʻana i ka hypertension arterial o kekahi pohihihi. Ma hope o ka lawelawe waha hoʻokahi, ʻo ka hopena ʻoi loa o Noliprel A Forte i loaʻa aku ma hope o nā hola 4-6 a kūkaʻa no 24 mau hola. 'Lelo ʻia ke koena (e pili ana i ka 80%) kaomi o ACE e mālama ʻia i 24 mau hola ma hope o kona hoʻoponopono.

Loaʻa iā Perindopril kahi hopena hypotensive me ka hana haʻahaʻa a me ka hana renin plasma maʻamau.

Hoʻohui ka hui me ka diuret thiazide i ka nui o ka hopena antihypertensive, e hōʻemi ana i ka hopena o ka hypokalemia ma muli o ka hoʻokomo o ka diuretics.

ʻO ka hui pū ʻana me kahi inhibitor ACE a me kahi ʻāopaoopagelima receptor II (ARA II) i loko o nā mea maʻi me ka mōʻaukala o nā maʻi cardiovascular a me cerebrovascular paha, nā mea maʻi me ka maʻi type 2 (me ka hōʻino kino ʻōmaʻomaʻo i hoʻopaʻa ʻia), type 2 diabetes and nephropathy diabetes ʻaʻole i paʻa ʻo ia i nā clinically. ka hopena maikaʻi loa ma ka hopena o ka renal a me / a i ʻole nā hanana cardiovascular a i ʻole ma nā kumukūʻai make. Akā ma hope o ka hoʻohālikelike ʻana me ia me ka monotherapy, ua ʻike ʻia i ke kūpaʻa ʻana o ka hui ʻana o ka mea paʻa o ka ACE inhibitor a me ARA II, ka piʻi ʻana o ka hoʻoulu ʻana i ka hyperkalemia, ka maʻi renal failed a me / a i ʻole ka piʻi ʻana o ka hypotension arterial.

I ka noʻonoʻo ʻana ua like nā ʻano o ka intragroup pharmacodynamic o ACE inhibitors a me ARA II, hiki ke hopena kēia mau hopena i ka hui pū ʻana o ka perindopril a me ARA II.

ʻAʻole ia e kauoha i hoʻohana like i nā lilo ACE inhibitors a me ARA II i nā mea maʻi me ka nephropathy maʻi maʻi.

Hoʻohui ʻia ka aliskiren i ka type 2 diabetes mellitus a me nā maʻi maʻi pāpaʻi a me / a me nā maʻi cardiovascular i ka maʻi ACE a ARA II inhibitor therapy hoʻonui i ka hopena o ka hanana ʻino, ʻo ia hoʻi ka make cardiovascular, stroke, hyperkalemia, hypotension, a me kahi hana ʻole. . ^ E Ha yM.

ʻO ka hoʻohana ʻana i ka indapamide i nā pali liʻiliʻi e loaʻa ai kahi hopena diuretic liʻiliʻi e hoʻoemi ai i OPSS, e hoʻomaikaʻi i nā waiwai elastic o nā arela nui, e hoʻolako ai me kahi hopena antihypertensive. Ma waho o ka hoʻopiʻi ʻana i ka pae o ka lipids i loko o ke koko koko (triglycerides, ka nui o ka kolamu, LDL, HDL) a me nā metabolism i kālaiʻu (me nā mea maʻi me ka maʻi diabetes mellitus), kōkua indapamide e hōʻemi i ka GTL.

Lapaʻau lāʻau

ʻO nā hiʻohiʻona pharmacokinetic keʻano o ka monotherapy me kēlā me kēia lāʻau lapaʻau ʻaʻole e loli me ka hui pū ʻana o perindopril a me indapamide.

Ma hope o ka lawelawe waha, hele koke ʻo ia i ka hoʻolowale ʻana, hiki ke loaʻa ka bioavailability mai 65 a 70%. Ma kahi o 20% o ka nui o ka lāʻau i mālamaʻia i ka biotransformed i loko o ka perindoprilat metabolite. Ka ʻaila nui (C_max) i ka plasma koko i hōʻea ʻia ma hope o 3-4 mau hola. ʻO ka helu hāhuli i hoʻoiho pinepine ʻia ka hoʻololi ʻana o ka perindopril i perindoprilat me ka hopena koʻikoʻi lāʻau lapaʻau.

Ma hope o ka lawe wikiwiki ʻana i ka maʻi indapamide mai ka gastrointestinal tract piha piha ʻana i ka maʻa i lawe ʻia, kāna C_max i ka pili koko i ka wai i loko o kahi 1 hola mai ka manawa o ka hoʻomaʻamaʻa ʻana.

Mālama ka protein protein: perindopril - liʻiliʻi loa ma ka 30%, indapamide - 79%.

ʻO ka weheʻole o ka perindoprilat e pili ana i ka wikiwiki, no laila ke hoʻomau nei ka hapalua-ola (T_1/2) perindopril - 25 hola. Ua hōʻea ke kāʻei kaulike ma hope o nā hola 96.

Hoʻopau ʻo Perindopril i ka pāʻana placental.

Ke hoʻohana pinepine nei ʻo Noliprel A forte ʻaʻole i alakaʻi i ka cumulation i loko o ke kino o kāna mau mea hoʻoikaika.

Ua hoʻohālikelike ʻia ka Perindoprilat e nā ʻōpū, T_1/2 He 3-5 mau hola.

T_1/2 indapamide inu a 19 hola. Hoʻokuʻu ʻia ia i loko o ke ʻano o ka metabolite kāohi ʻole: ma o nā keiki - 70% o nā kiʻi i lawe ʻia, ma o nā ʻōpū o ka 22%.

ʻO ka hoʻomaʻemaʻe e pili ana i ka perindoprilat i ka wā dialysis he 70 ml / min.

Me ka renal a me ka puʻuwai hema, a me ka poʻe maʻi maʻi, ua emi iho ka excretion o perindoprilat.

Me ka cirrhosis o nā pepelu, e hoʻomaʻemaʻe ʻia ka maʻi hepatic o perindopril ma o 2 mau manawa, akā ʻaʻole ia e pili i ka nui o ka perindoprilat, no laila ʻaʻole koi ka hoʻoponopono hoʻoponopono.

I nā maʻi me ka pilikia ʻole, ʻaʻole i loli nā pharmacokinetics o indapamide.

Nā Hoʻohui

hōʻeha ʻole ka naʻau, me ka paʻakikī o ka encephalopathy,
pilikia hōʻeha loa me ka hana ʻana me ka creatinine (CC) ma mua o 30 ml / min,
bilateral renal stenosis,
ka hele ana o kekahi o ka hana hana,
ka hoʻohana ʻia ʻana o ka hemodialysis,
hypokalemia
decompensated decompensated hana pohihihi,
hui pū me nā lāʻau lapaʻau e hoʻolōʻihi i ka manawa QT,
hui pū me nā lāʻau antiarrhythmic e hiki ai i ka arrhythmias ventricular e like me "pirouette",
hana i ka manawa like me nā lāʻau lapaʻau e pili ana i ka aliskiren i nā mea maʻi me ka maʻi mellitus a i ʻole ka hopena ʻole o ka renal function (GFR ma mua o 60 ml / min i ka 1.73 m2 o ka ʻōpū o ke kino o ka kino),
glucose-galactose malabsorption syndrome, galactosemia, lactase deficiency,
hoʻoilina aiʻole kona indiosathema angioedema,
kahi hōʻike e pili ana i ka mōʻaukala o ka angioedema, me ka hoʻohana ʻana o ka inhibce ACE,
wā hāpai
hana waiū
makahiki i 18 makahiki
ua hoʻokū ʻia nā hypersensitivity i nā mea ʻē aʻe ACE a i ʻole sulfonamides,
ka maʻi kūlohelohe o nā mea āpau o ka lāʻau lapaʻau.

Me ka makaʻala, e kuhikuhi ʻia e kuhikuhi iā Noliprel A forte i nā poʻe maʻi me ka loaʻa ʻole o ka puʻuwai naʻau o ka papa hana IV e like me ka palapala ʻana ʻo NYHA (New York Heart Association), angina pectoris, hypovension renovascular, stenosis aortic, stertosis hypertrophic obstructive cardiomyopathy, hōʻeha o ka maʻi hemopoiesis hōʻemi (hoʻemi ʻia ka nui o ke koko) (e like me ka hopena o ka lawe ʻana i ka diuretics, ma muli o kahi kīʻaha paʻakai paʻakai, me ka luaʻi, ka maʻi a i ʻole ka hemodialysis), cerebrovascular abolevaniyami, mimikō, ake e loaa, systemic connective'aʻaʻa maʻi (me scleroderma, systemic lupus erythematosus), a me ka lability o ke koko,, hyperuricemia (poe pu urate gout a me ka nephrolithiasis), i loko o ka kūpuna, e like me ka pono me ka 'oihana' âlapa a me nā mea maʻi Naʻau.

Eia kekahi, e kuhikuhi ʻia ka akahele ʻana i ka wā e hoʻohana ai i nā immunosuppressants, ka hoʻomākaukau ʻana i lithium, hemodialysis e hoʻohana ana i nā membranes kiʻekiʻe, desensitization, ma mua o ka hana LDL apheresis, anesthesia, a me ka hoʻohuli.

Nā hopena hopena

mai ka pūnaehana nūnaehana kikowaena: pinepine - ka ʻeha, ka vertigo, ka ʻeha, ka asthenia, paresthesia, pinepine - hana i ke ʻano, ke ʻano hopohopo, ʻeha ʻole - hilahila, ʻaʻole i hoʻonohonoho ʻia.
mai nā maʻi lymphatic a me ka hoʻopalike: loa loa - leukopenia, neutropenia, thrombocytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, anemia (ma hope o ka hoʻohuli ʻana i ka lolo, hemodialysis).
mai ka pūnaehana cardiovascular: pinepine - he mau hōʻailona i hōʻemi i ke koko (me ke hypotension orthostatic), ʻolua - loaʻa i ka arrhythmias cardiac (me ka bradycardia, tachycardia ventricular, fibrillation atrial), angina pectoris, myocardial infarction, pinepine ʻole i hoʻokumu ʻia - pirouette type arrhythmia, komo ka momona
mai nā mea ulu kino: pinepine - tinnitus, ʻike maka ʻole ʻia
mai ka papa hana hanu, umauma a me nā ʻōpū mediastinal: pinepine - ka wā mau o ka maloʻo maloʻo (ma muli o ka hoʻohana mau ʻana o ka perindopril), pōkole o ka hanu, pinepine - bronchospasm, aneane loa - rhinitis, eosinophilic pneumonia.
mai ka papa hana ʻana: pinepine - ka ʻae ʻole o ka ʻono, ka malo maloʻo, hoʻemi ka makemake, ka ʻōpū, ka luaʻi ʻana, ka ʻeha o ka epigastric, ka ʻōpū o ka ʻōpū, ka constipation, ke ʻōpala, nā dyspepsia, aneane loa - pancreatitis, angioedema, jaundice cholestatic, cytolytic a i ʻole hepatitis cholestatic, ʻaʻole i hoʻokumu pinepine ʻia ke alapine - hepatic encephalopathy (me ka huakaʻi mālama concomitant),
nā maʻi kūlohelohe: pinepine - urticaria, angioedema o ka maka, nā lehelehe, alana, ʻōpū, nā meleminal o nā hua leo a me / a larynx paha, ma kahi o ka predisposition i ka hopena bronchial a me nā hopena alerine - hypersensitivity hopena,
nā umauma dermatological: pinepine - kaʻeha, ʻehaʻeha o ke kino, ka pīhoihoi maculopapular, līkika - ke kaumaha nei i ke ʻano o ke ʻano o ka systemus lupus erythematosus, purpura, aneane loa - ʻehā necrolysis epidermal, erythema multiforme, Stevens-Johnson syndrome, photosensitivity,
mai ka musculoskeletal system: pinepine - nā māhini o ka mākona,
mai ka ʻōpiopio: ka pinepine - impotence,
mai nā urinary system: pinepine - hiki ʻole i ka renal ke hele a maikaʻi loa - hoʻonā i ʻole ka hopena renal,
nā mākaʻi ʻinao: ʻaʻohe - hypercalcemia, ʻaʻole i hoʻokumu ʻia ke alapine - ka piʻi ʻana o ka manawa QT ma ka electrocardiogram, he nui aʻe ka pae o ka glucose a me ka waika uric i loko o ke koko, he nui ka hana o nā huina o ka huina, hypokalemia, hyponatremia, hypovolemia, hyperkalemia, he hōʻemi iki aʻe i ka ʻike ʻana o ka bun i loko o ka urine a me ka hoʻokahe koko,
nā hopena ākea: pinepine - asthenia, pinepine - hoʻonui ʻia ʻana.

Ke keu

Nā hōʻailona: kahi hōʻailona i hoʻokahe ʻia i ke koko, ka mea i hele pū me ka nausea, ka luaʻi, ka dizziness, ka hiamoe, ke kīwī, nā hilahila, ka oliguria, i kekahi manawa e hoʻohuli i ka anuria ma ke ʻano o ka hypovolemia, pane wai-electrolyte i hoʻopiha (hyponatremia a me hypokalemia).

Mea Hoʻolālā: ka waila o ka gastric waʻa, ka koho hoʻohālikelike i hoʻōla, hoʻihoʻi hou ʻana i ka kaulike wai-electrolyte. Me ka hypotension koʻikoʻi, pono e kau i ka mea maʻi ma kona kua a hāpai ʻia kona mau wāwae. No ka hōʻoia ʻana i ka mālama pono ʻana i ke ʻano o ka mea maʻi, me ka hypovolemia - e hoʻokō i ka iv (infusion) infusion o 0.9% sodium chloride solution.

ʻO paha ka hoʻohana ʻana i ka dialysis.

Nā ʻōlelo kikoʻī

Hoʻohana ʻia ka hoʻohana ʻana o Noliprel A forte me nā hopena hopena hiʻona o ka monotherapy me ka perindopril a me ka indapamide ma nā pae haʻahaʻa therapeutic haʻahaʻa. I nā maʻi i loaʻa ʻole i ka maʻi me ka ʻelua mau lāʻau antihypertensive, aia ke hoʻonui hou ʻana o ka idiosyncrasy, no laila ke koi ʻia ka mālama ʻana e hōʻemi i kēia hopena.

Inā loaʻa nā hōʻailona o ka hana 'ole a me ka hana' ole i ka wā o ka ho'ōla, ho'ōnaia me ka lāʻau. No ka hoʻomau hou i ka lāʻau hoʻohui, ʻoi aku ia e hoʻohana i nā helu haʻahaʻa o kēlā me kēia lāʻau lapaʻau ai ʻole i kuhikuhi wale i kekahi o lākou. I kēia hihia, pono i nā mea maʻi ke nānā maʻamau i ka paʻakai serum a me nā pae creatinine. Hoʻopili ʻia nā haʻawina 14 mau lā ma hope o ka hoʻomaka ʻana o ka mālama ʻana a laila 1 ka manawa i 60 lā.

I nā mea maʻi me ka puʻuwai koʻikoʻi koʻikoʻi a me kahi hana mua ʻole o ka renal function (me ka renal artery stenosis), hana pinepine ʻole i ka hopena o ka renal.

Kahi koke ka ulu ʻana o ka hypotension arterial me ka hyponatremia mua, aemaise i nā mea maʻi me ka stenosis renal renal. No laila, ma hope o ke ʻano o ka maʻi a i ʻole ka luaʻi paha, e pono e noʻonoʻo i ka dehydration hiki i ke kino a me ka hoʻohaʻahaʻa ʻana i ka ʻike o ka electrolyte i loko o ke koko koko. Me ka hypotension arterial koʻikoʻi, hōʻike ʻia ka lawelawe ʻana iv o 0.9% kaomi sodium chloride.

ʻO ka hypotension arential ke kumu ʻaʻole no ka hoʻokuʻu ʻana i ka ʻoihana. Ma hope o ka hoʻihoʻi hou o BCC a me ke koko, hiki ke mālama ʻia ke mālama ʻana me ka hoʻohana ʻana i nā haʻahaʻa haʻahaʻa o ʻelua mau mea ikaika a i ʻole kekahi o lākou.

Pono e mālama ʻia ka hoʻomaʻamaʻa ʻana me ka mālama pinepine ʻana o ka pāhana i ka plasma koko, a me ka maʻi diabetes mellitus a me ka pana ʻole ʻole.

ʻO ke hoʻohana ʻana o Noliprel A Fort e hoʻokuʻu ʻia o 24 mau hola ma mua o ka hoʻomaka ʻana o ka desensitization.

Ma mua o kēlā me kēia kaʻina LDL apheresis e hoʻohana ana i ka dextran sulfate, pono e hoʻokaʻawale ke keʻena o kahi inhibitor ACE.

I nā mea maʻi e hoʻomanawanui ana i ka terapi perindopril, ʻaʻole hiki ke hoʻohana ʻia nā membranes kahe nui i ka wā hemodialysis. Pono lākou e hoʻololi i nā membranes a i ʻole nā ʻano anti antihypertensive e pono e kuhikuhi i ka mea maʻi e hoʻohana ai i nā lāʻau lapaʻau o kekahi ʻano lāʻau lapaʻau ʻē aʻe.

Ma ka hōʻike ʻana o ka umī mau ʻana i kū mai ai i ka wā o ka hoʻolaʻa, pono e hāpai ʻia i ka noʻonoʻo o ka hoʻohana ʻana o kahi inhibce ACE ke kumu o kona ʻano.

Ma muli o ke kīhaha nui o ka hoʻomohala ʻana i ka neutropenia, agranulocytosis, thrombocytopenia, a me anemia, pono pono e nānā pono i ka wā e koho ai i ka perindopril i nā maʻi me nā maʻi ʻōnaehana o ka kiko huakaʻi e lawe pū ana i nā immunosuppressants, procainamide a allopurinol, e like me ka hana mua ʻole o ka hana renal. Hōʻalo kēia mau mea maʻi i ka hoʻomohala ʻana i nā maʻi koʻikoʻi, kū pinepine i ka neʻe ʻana i ka antibiotic therapy. Hoʻohana ʻia ka hoʻohana ʻana o Noliprel A Forte i kēia mahele o nā mea maʻi e hele pū me ka nānā wā maʻamau o ka helu o leukocytes i loko o ke koko. Hōʻike ʻia lākou e pili ana i ka pono e nīnau koke i ke kauka inā inā he ʻehaʻeha, ke kuni, a me nā hōʻailona ʻē aʻe o ka maʻi maʻi.

Me ka hoʻohaʻahaʻa ʻana i ka protein electrolytes plasma a me ka hypovolemia koʻikoʻi, hoʻomaka ka hoʻokahe haʻahaʻa, renen artery stenosis, hōʻeha o ka puʻuwai, a i ʻole cirrhosis o ka ate me ka edema a ascites, nui ka hoʻōina o ka renin-aldosterone-angiotensin system (RAAS) i hiki mai i ka hopena o ka polaka o kēia pūnaehana e perindopril. Hiki ke hele pū ʻia nā kūlana o ka mea maʻi me ka neʻe nui o ke kahe koko, ke hoʻonui ʻana i ka creatinine i loko o ke koko koko, ka hoʻomohala ʻana o ka hiki ʻole o ka hana renal. ʻO ka maʻamau, ʻike ʻia kēia mau hanana i ka wā 14 o nā lā lapaʻau. Hoʻomaopopo ʻia e hoʻomau i ka lawe ʻana i ka lāʻau me ka haʻahaʻa haʻahaʻa.

No ka hypertension i loko o nā mea maʻi me ka maʻi naʻau coronary (CHD), kaʻe o ka cerebrovascular, hōʻeha nui o ka naʻau a me / a i ʻole a i ʻole a i kahi maʻi maʻi 1, pono e hoʻomaka ʻia ka mālama ʻana me nā haʻahaʻa haʻahaʻa. ʻO nā mea maʻi me ka maʻi ʻala coronary e lawe i ka inhibitor ACE me nā beta-blockers.

Ma muli o ke kīpē o ka hoʻomohala ʻana i ka anemia i loko o nā poʻe maʻi e hele ana i ka hoʻololi ʻana i ka lolo a i ʻole ke komo ʻana i ka hemodialysis, pono e mālama ʻia nā maʻi e nā hōʻike hematological.

Ma mua o kahi hōʻeha nui, pono e hoʻokuʻu ʻia ʻo Noliprel A Fort i 24 mau hola ma mua o ka hoʻomaka ʻana o kahi anesthesia aoao.

Pono e noʻonoʻo i ka poʻe maʻi i ka lāhui Negroid, ʻaʻole i ʻōlelo ʻia ka hopena antihypertensive o ka perindopril.

I ka hihia o ka hana lūlū hemahema, hiki i ka indapamide ke hana i ka hoʻokumu ʻana i ka encephalopathy hepatic, koi i ka hoʻopau koke ʻana i ka lāʻau.

ʻO ka koho ʻo Noliprel A forte e pono e lawe i ka hopena o nā noi ʻana o ka hoʻākoakoa wai-electrolyte (me ka ʻike pū o nā sodium, potassium a me nā calcium i loko o ke kaila koko) o ka mea maʻi, ma hope o ka mālama ʻia ʻana o ka ʻoihana maʻamau.

ʻO ka hypokalemia i nā maʻi maʻi maʻi, nā mea maʻi huanihue, nā mea maʻi me ka puʻuwai naʻau, ka maʻi naʻau coronary, cirrhosis (me ka edema a ascites paha) e hoʻonui i ka hopena o nā mea a pau o ka glycosides cardiac a hoʻonui i ka hopena o ka arrhythmias.

I ka wā maʻi o ka diuretic, ʻoi ka nui o ka waikawa plasma uric e hoʻonui ai i ka ulu ʻana o nā puʻupuʻu gout.

Hiki ke hōʻoia piha ʻia i ka hopena o ka lāʻau me ka thiazide a me ka diuretics like-thiazide me ka hana ʻole a i ʻole ka pale ʻē aʻe. ʻO ka hoʻoneʻe ʻana i ka plasma i loko o nā poʻe maʻi e pono ma lalo o 2.5 mg / dL a i ʻole 220 μmol / L. No nā poʻe maʻi maʻi, ua hoʻoponopono ʻia no ka makahiki, ka wahine, a me ke kaumaha me ka hoʻohana ʻana i ka rumē ʻo Cockcroft. Hoʻoholo ka hōʻailona maʻamau o ka neʻe ʻana o ka plasma creinine i nā kāne ma ka hoʻonui ʻana i ka ʻokoʻa (140 mau minuke makahiki) e ka paona o ka mea maʻi ma ke kilograms a hoʻokaʻawale i ka hopena e ka neʻe ʻana o ka plasma creatinine (μmol / L), hoʻonui ʻia e 0.814. I mea e hoʻoholo ai i kēia hōʻailona no ka wahine, pono e hoʻonui ʻia ka hopena hope ma ka 0.85.

No ka poʻe maʻi me ka hana renal maʻamau, ʻaʻole kūlohelohe ʻia ke ʻano o ka neʻe ʻana o ka hana renal functionally. Me ka hiki ʻole o ka maikaʻi renal, ke emi nei ka hōʻemi i ka GFR, ka nui o ka piʻi ʻana o ka urea a me ka kumu hana i loko o ke koko koko hiki ke loaʻa i kahi kūlana a me ka hopena hou.

Ma muli o ka hopena o ka hopena photosensitivity i ka wā o ka hoʻohana ʻana o Noliprel A Forte, ua pono ia e pale aku i ka hoʻolaha ʻana i ka lā a i ʻole ka radiation ultraviolet artipio.

Pono e noʻonoʻo ʻia i ka wā e mālama ana i ka mālama doping i loko o ka mea hoʻokūkū, hiki i ka indapamide ke hāʻawi i kahi hopena maikaʻi.

Hoʻokomo i ka hiki ke lawe i nā kaʻa a me nā mīkini paʻakikī

ʻAʻole Noliprel A forte e hoʻonāukiuki i ka hopena psychomotor. Eia nō naʻe, ma muli o ka loaʻa mau o nā hanana pōʻino e kū mai i ka wā o ke kahe o ke kahe o ke koko i ka wā a i ke hoʻoponopono ʻana i ka lapaʻau ʻana, e aʻo ʻia ka mālama ʻana i ka wā o ka lawe ʻana i nā kaʻa a me nā ʻano paʻakikī, i ka hoʻomaka ʻana o ka hopena.

ʻŌpū a me ka lactation

Hoʻopili ʻia ke hoʻohana ʻana o Noliprel A Forte i ka wā gestation a me nā hōʻuluʻulu umauma.

Ke hoʻolālā nei i ka hāpai ʻana a i ʻole ke kuhi ʻia i ka wā o ka maʻi lapaʻau, pono e hoʻoneʻe ʻia ka lāʻau a me kahi luna hypotensive i ʻae ʻia no ka hoʻohana ʻana i ka wā hāpai.

ʻO ka hoʻohana ʻana o ka inhibitor ACE i ka II - III trimesters o ka hapai hiki ke hōʻeha i ka hoʻomohala ʻana i ka hanana ʻana (ua hōʻemi ka hana ʻana, oki i ka ossification o nā iwi o ka ʻōpala, oligohydramnios) a me ka hoʻomohala ʻana o nā hoʻopiʻi i ka pēpē (renal failed, hypotension arterial a / a i ʻole hyperkalemia).

Eia kekahi, ʻo ka lōʻihi o ka lāʻau me ka thiazide diuretics i ka trimester III o ka hapai e hoʻopilikia hewa i ka kahe koko-uterental, a ke kumu o ka hypovolemia i ka makuahine.

Me ka hana pūnāwai paʻa ʻole

Ua hoʻohana ʻia ka hoʻohana ʻana o Noliprel A Forte i ka hiki ʻole o ka pilikia nui ʻole (CC ma mua o 30 ml / min).

I ka hana ʻoleʻana i ka maʻi i nā mea maʻi me CC 30-60 ml / min, pono ke hana ʻana i ka lāʻau lapaʻau hui ʻia ma hope o ka monotherapy preliminary me kēlā me kēia mea hana. Pono e hoʻohana i nā dosis i hiki ke hoʻokō i ka hopena pāmaʻomaʻo loa.

In renal failed me ka CC o 60 ml / min a i luna, ua kau ʻia nā ʻano maʻamau maʻamau ʻo Noliprel A forte, me ka mālama ʻana me ka mālama maʻamau ʻana i ka plasma creatinine a me nā pae pākia.

Hoʻohui nūhou

ka mākaukau lithium: ka hui pū ʻana o kahi inhibitor ACE a me ka hoʻomākaukau ʻana i ka lithium e hoʻonui i ka nui o ka hoʻonui hou ʻana o ka piʻi ʻana o ka lithium i loko o ke kō koko a me ka hoʻomohala ʻana i nā hopena o nā mea laʻa. ʻO ka heleʻana o diuretics thiazide e hoʻonui wale i nā hana e kū mai ana. ʻAʻole kuhikuhi ʻia ka lāʻau hoʻohui me ka hoʻomākaukau ʻana o ka lithium. Inā e pono e hana i ka hui hoʻohui, e nānā pono ʻia nā ʻike lithium ma ka plasma koko.
baclofen: hoʻonui i ka hopena hypotensive. No ka hoʻoponopono pono ʻana i nā lāʻau lapaʻau, pono ke nānā ʻia a me nā neʻe koko.
Non-steroidal anti-inflammatory drug (NSAIDs) ((me ka lā o ka nui o ka acetylsalicylic acid e ʻoi aku ma mua o 3 g): cyclooxygenase-2 inhibitors (COX-2), non-selective NSAIDs a me nā hopena anti-inflammatory o ka acetylsalicylic acid hoʻemi i ka hopena antihypertensive o ka perindopril a hoʻonui i ka hopena o ka hopena kumu ʻole a me ka hopena o ka hopena anti-inflammatory o ka acetylsalicylic acid hoʻemi i ka hopena antihypertensive o perindopril hoonui i ka serum potassium content (ʻoi aku me ka wā i emi ka mua o ka hana keiki)
antidepresants tricyclic, antipsychotics (antipsychotics): me ka hoʻohana ʻana o Noliprel A forte, hoʻonui lākou i ka hopena hypotensive, hoʻonui i ka hōʻeha o ka hypthension orthostatic,
corticosteroids, tetracosactide: lilo i ka hoʻemi ʻana i ka hopena antihypertensive. Hoʻokumu ka hana o nā corticosteroids i ka noho ʻana o ka wai me ka wai o ka sodium,
nā lāʻau lapaʻau antihypertensive a me nā vasodilators: hiki i ka hopena ke kiʻekiʻe i ka hopena hypotensive o ka lāʻau. Hiki i nā Nitroglycerin, nitrates a me nā vasodilators ke hoʻohaʻahaʻa i ke koko,
Pune-sparing diuretics (me ka amiloride, spironolactone, eplerenone, triamteren), mākaukau pākui, nā mea paʻahana e pili ana i ka paʻakai e pono ai: hiki i kēia mau mea lawelawe ke hoʻoulu nui i ka pae pākela o ka paʻū i ka punana koko, a me nā mea momona. Ma kēia mea, me ka hypokalemia hoʻopaʻa ʻia, ʻo kā lākou hui pū me ka lāʻau lapaʻau e pono me ka mālama pono ʻana o ka waihona pākela i loko o ka ona koko a me nā pākeke ECG,
estramustine: ua hoʻonui ʻia ka hopena o ka hoʻolālā ʻana i ka angioedema a me nā hanana kūlike e like ai
ʻO nā derivatives no ka insulin a me ka sulfonylurea (nā mālamalama hypoglycemic waha): i nā mea maʻi me ka maʻi diabetes, hiki ke hoʻonui ʻia i ka hopena hypoglycemic o ka insulin a me ka deralona sulfonylurea,
allopurinol, immunosuppressive a me cytostatic agents, corticosteroids no ka hoʻohana systemic, procainamide: hui pū me kēia mau mea e hoʻonui i ka hopena e ulu ai le leenenenia,
ka nui anesthesia lāʻau: ka hoʻohana ʻana o nā lāʻau anesthesia laulā e hoʻonui i ka hopena antihypertensive,
thiazide a me "loop" diuretics: nā koina nui o ka diuretics hiki ke alakaʻi i ka hypovolemia a me ka hypotension arterial,
linagliptin, sitagliptin, vildagliptin, saxagliptin (gliptins): hoʻonui i ka hopena o ka angioedema,
sympathomimetics: hiki nāwaliwali o ka hopena antihypertensive,
Nā mākau gula gula: e kū'ē ana i ke kua o ka lawelawe ʻana o ka mākaukau gula, e ulu nā ʻano like nitrate (ʻo ka hyperemia ʻulaʻi o ke alo, hypotension arterial, hōʻea, a luaʻi)
quinidine, disopyramide, hydroquinidine (antiarrhythmic drug of class IA), ibutilide, amiodarone, dofetilide, bretilia tosylate (antiarrhythmic drug of class III), sotalol, chlorpromazine, ciamemazine, levomepromazine, thioridazine, trifluopera, droperidol, haloperidol, pimozide, bepridil, diphenyl methyl sulfate, cisapride, erythromycin a vincamine (iv), misolastine, moxifloxacin, pentamidine, halofantrine, sparfloxacin, methadone, terfenadine, astemizole: Hiki i ka indapamide ke hāʻawi i ka hōʻemi o ka paʻakai i ka plasma koko a me ka hiki ʻana o ka arrhythmias type pirouette. Inā e pono e kuhikuhi i kēia mau kālā, pono e mālama pono i ka mālama o ka paʻakai ma ka pili koko a me ke kikowaena QT.
amphotericin B (iv), nā glucocorticoids systemic a me mineralocorticoids, tetracosactides a me nā laxatives e hāpai i ka ʻōpū o ka ʻōpū: hoʻonui i ka kuʻuna o ka hypokalemia,
glycosides cardiac: pono e noʻonoʻo i ka hypokalemia hiki ke hoʻoikaika i ka hopena o nā mea laʻa o ka glycosides cardiac, no laila, ua manaʻo ʻia e kāohi i ka pāhare pālolo ma loko o ke kaila koko a me nā ʻōhua ECG a hana i ka hoʻoponopono kūpono i ka ʻoihana,
metformin: pono ke nānā ʻia o ka hana ʻole o ka renal i hana i ka wā e lawe ana i kahi diuretic, i hui pū ʻia me ka metformin, e hoʻonui ai i ka nui o ka maʻi lactic acidosis. Inā hoʻāʻo ʻia ka mea hana i ka plasma koko i nā kāne ma mua o 15 mg / l, a me nā wahine - 12 mg / l, ʻaʻole pono ke kuhikuhi ʻana i ka metformin.
ʻO nā mea ʻokoʻa i loko o ka iodine: nā koina nui o nā iodine e hoʻopuni ai i ka mana o ke kuihuwehi (no ka hoʻokomo ʻana i nā lāʻau diuretic) o ka kino e hoʻonui i ka hopena o ka hiki ʻana o ka renal paʻakikī, e koi ai i ka uku hoʻemi no ka wai ʻole ma mua o ka hoʻohana ʻana i nā mea kūlike i ka iodine.
nā paʻakai kaleka: kahi hōʻemi o ka hana o nā calcium calcium e nā ʻoka, hiki ke hoʻonui i ka nui o ka hoʻomohala ʻana i ka hypercalcemia,
cyclosporine: ʻaʻole loli o ka manaʻo o ka cyclosporine i loko o ke kaila koko, akā hiki ke hoʻonui i ka likinine i loko o ke koko koko, me ka ʻano maʻamau o ka wai a me nā paʻakai sodium.

The analogs of Noliprel A forte are: Noliprel, Noliprel A Bi-forte, Perindopril PLUS Indapamide, Co-Parnavel, Indapamide / Perindopril-Teva, Co-Perineva, Co-Preness, Perindapam, Perindide, Perindopril-Indapamide Richter.

ʻO ka wehewehe ʻana o nā lāʻau paʻi

ʻO ka hui pū ʻana o nā papa i loaʻa iā Perindopril a me Indapamide. Ua loaʻa i nā mea ʻelua nā hopena antihypertensive, akā e hoʻohaʻahaʻa i ka tonometer i nā ʻano like ʻole.

ʻO Perindopril kahi mea hoʻoneʻe ACE, a ʻo Indapamide no nā papa o ka diuretics sulfonamide. I ka hui pono, hoʻonui kēia mau mea i ka hana a kekahi.

E kau ana i kahi lāʻau lapaʻau no ka hōʻemi ʻana i ka hoʻohaʻahaʻa naʻau. Hoʻomaʻamaʻa pinepine, ke kauka nei ke kauka iā Noliprel i ka mālama ʻana o ka maʻi hypertension maʻi ʻole.

Ke ulu nei ka hopena hypotensive kiʻekiʻe ma hope o hoʻokahi mahina o ka hoʻokele a hoʻomau i ka manawa lōʻihi. Hauleʻa kēia lāʻau lapaʻau inā ʻaʻole kōkua iki nā lāʻau antihypertensive.

I ka manawa like, haʻahaʻa ka uku o nā papa. He nui nā kānaka e kūʻai iā Noliprel, ʻaʻole lākou e ʻike e lawe. Ma muli o kēia, kū pinepine nā hoʻopiʻi i ka hana a ʻaʻole e hoʻemi nui ka huahana i ka tonometer.

No nā ʻikepili ma Noliprel A Fort

He kūpono nā manaʻo e pili ana iā Noliprel A Fort. ʻO nā mea maʻi me ka ʻike i ka mālama ʻana i ka hōʻike hypertension arterial e hoʻololi ana i ka lawe ʻana iā Noliprel A forte i ʻae iā lākou e hoʻomaʻamaʻa i ke koko, a me ka paʻa mau i ka paʻa. Ke kuhikuhi nei i ka hopena o ka laiki, ua ʻōlelo ʻia nā mea hoʻohana e hoʻomaka e lawe i ka lāʻau lapaʻau me ka ʻole e kūkākūkā me ke kauka.

Nā helu o ka Noliprel

Hoʻokuʻu ʻia ʻo Noliprel i kekahi mau ʻano. Mālama maikaʻi ia i nā mea maʻi a me nā kauka e hoʻomaopopo i kēlā assortment.

Noliprel A Bi-Forte

Hoʻohālikelike ʻia nā ʻano ʻāpana like ʻole:

Noliprel (loaʻa 2 mg perindopril me 0.625 mg diuretic),
ʻO Noliprel Forte (ʻo ka nui o ka nui o ka indapamide he 1.25 mg, a ʻo perindopril he 4 mg),
Noliprel A Forte (indapamide - 1.25 mg, perindopril - 5 mg),
Noliprel A Bi-Forte (i kēlā me ka perindopril i loko o kahi waihona o 10 mg, a me kahi diuretic - 2,5 mg),
Noliprel A (2,5 mg perindopril a me 0.625 mg indapamide).

Noliprel A Bi-Forte e hōʻike pinepine ʻia i ka nānā ʻana i ka nui kiʻekiʻe. Inā nui ka nui o kēia maʻi, koho ke kauka i nā papa me kahi haʻahaʻa haʻahaʻa o ka perindopril a me ka indapamide.

ʻO ka lāʻau Noliprel A, kahi Bi-Forte a me A Forte aia i ka arginine acid amino, i loaʻa ka hopena pono ma ka pūnaehana cardiovascular.

No laila, inā aia nā pilikia o ka naʻau, pono ka hoʻohana ʻana i nā lāʻau i luna. No kēlā me kēia mea maʻi, ua koho pono ʻia ka nui o kēlā me kēia, me ke ʻano he pili i nā ala, he makahiki. Hoʻomaopopo ʻia nā maʻi maʻi hypertensive o ka wā kiʻekiʻe e hoʻomaka i ka mālama ʻana me kahi papa hoʻokahi.

Pehea e inu ai i nā papa noliprel?

ʻO ka lāʻau hoʻohui i lawe ʻia i hoʻokahi manawa i ka lā. He mea maʻalahi loa ia, ʻano nui no nā poʻe ʻokiʻoki a paʻakikī paha.

Inā ʻōlelo ke kauka iā Noliprel, pehea e lawe ai i kēia lāʻau lapaʻau ma mua a i ʻole ma hope o ka ʻai he pilikia wela no nā maʻi he nui.

ʻAʻole hāʻawi ka ʻōlelo aʻo i ka pane. Ua hōʻike ʻia wale nō ke inu ʻia ka lāʻau lapaʻau i ke kakahiaka.

Hoʻomaopopo nā kauka i ka hoʻohana ʻana i nā lāʻau lapaʻau ma mua o ka ʻaina kakahiaka. Hoʻomaopopo ʻia e lawe i nā papa i ka manawa like. A laila e hoʻomaʻamaʻa ʻia ka hopena o ka mālama ʻana a ʻaʻohe hanana hopena e loaʻa.

ʻO ke ʻano, ʻo ka kauka kau mua ka papa hoʻokahi i kēlā me kēia lā. Akā, inā he mahina ma hope o ka hoʻomaka ʻana o ka mālama ʻana i loaʻa ka hopena i makemake ʻia, ua kauoha ʻia ʻo Noliprel Forte me kahi ʻano o 4 mg perindopril a me 1.25 indapamide. I kekahi manawa kākau nā kauka i nā lāʻau lapaʻau ʻē aʻe. ʻO ka hoʻohālike, ua hoʻohui ʻia nā antagonist calcium. I kēia hihia, hoʻemi iki ʻia ka nui o ka lāʻau antihypertensive.

Inā he kiʻekiʻe loa ka nui o kēia, ʻike ʻia nā huaʻōlelo i lalo:

ninaki a me ka luaʻi
hiamoe
ʻoluʻolu
āhāhuʻe
nāwaliwali
brieociaia
nahoa
mai nāwaliwali
kahe kahel
ka hina nui ʻana i ke koko,
ka ʻohi ʻana i ka urine a i ʻole pinepine ʻia ʻoi.

Inā hele ʻia kēlā mau hōʻailona, e kāhea ʻoe i kahi ambulance. A i ka wā i loaʻa ai ka maikaʻi, pono ʻoe e hana i kahi manawa me kāu kauka e hoʻoponopono i ka dosage.

Hōʻike ʻia i ka wā hāpai

I ka wā hāpai i ka wā hāpai, hānau ʻia ke keiki ʻaʻole pono ia e lawe iā Noliprel.

Inā ua hana mua kekahi wahine iā ia i kēlā mau lāʻau, pono e hoʻokō ke papa a ʻōlelo aku i kahi kauka e kuhikuhi i kekahi lāʻau lapaʻau.

ʻAʻole i mālama ʻia nā haʻawina o nā hopena o nā inhibitor ACE i nā wahine hāpai. ʻAʻole ʻike ʻia paha ka hopena o ka lāʻau lapaʻau i ka hoʻomohala ʻana o ka pūpū.

No laila, pono e mālama ʻia. Ma hope o nā mea āpau, aia kahi pilikia o nā lāʻau lapaʻau e hoʻopilikia kino i ka hoʻokumu ʻana i nā iwi ʻōpala, kahi hana o nā keiki o ka pēpē. Hoʻonui pū kekahi i ka hopena o ka hypotension arterial.

Ua hoʻohui ʻia kēia lāʻau lapaʻau i ka umauma, me ka pale ʻana i ka lactation a me ka hoʻēmi ʻana i ka nui o ka waiū umauma i loko o kahi makuahine ʻōpio. E pale aku i ke ʻano o ka lawe ʻana i kēlā lāʻau lapaʻau, hiki i ka pēpē ke loaʻa hypokalemia, jaundice.

Hoʻolālā lōʻihi

ʻO ka Noliprel ka mea maʻamau i hoʻohana i ka lāʻau e mālama i ka maʻi hypertension.

Hāʻawi ʻia nā peni i kahi manawa lōʻihi, akā e aʻo ʻia e hoʻomaha pōkole. Inā ʻaʻole, hiki i ka lāʻau ke hōʻino i ka hana a nā keiki a me ke ake.

Pehea ka lōʻihi e inu ai iā Noliprel, āpau - pono kēia i hoʻoholo e ke kauka, i hāʻawi ʻia i ke ʻano o ka mea maʻi.

Hoʻokomo ʻia ka lāʻau i nā maʻi me nā pilikia ʻole o ka pilikia. Me ka maikaʻi renal gagal, ʻaʻole pono ka nui o ka nui o ka papa ma mua o hoʻokahi papa pākahi i kēlā me kēia lā.

I kekahi mau mea maʻi me ka hana renal impaired i ka wā e lawe ai i ka lāʻau lapaʻau, ʻike ʻia nā hōʻailona o ka hana o ka hemahema o kēia ʻano. I kēia hihia, ua pani ʻia ka mālama ʻana. I ka wā e hiki mai ana, ua ʻae ʻia e hoʻomau i ka hoʻohui ʻana i ka lāʻau lapaʻau, akā ma ka liʻiliʻi haʻahaʻa a me ke papa pōkole.

ʻAʻole kōkua ʻia ka mālama lōʻihi me ka Noliprel no kēlā mau maʻi:

angina pectoris ,,
sclerler,
pālahalaha maʻi
maʻi mellitus maʻiʻi
ʻōhumu lupus erythematosus,
hypertrophic cardiomyopathy,
stenosis aortic,
naʻau paʻakikī paʻakikī papaʻa.

Kōkua ka lāʻau lapaʻau e mālama i ke kaomi ma kahi pae o 130-140 / 80-90 mm. Hg. ʻAniā. a i lalo.

No laila, ʻo ka hopena o ke kūleʻa, ka puʻuwai o ka naʻau a me ka hana ʻole ʻana e hōʻemi i ka liʻiliʻi. Loaʻa ka pono o ka lāʻau lapaʻau e nā kauka.

Hoʻomaopopo nā kauka i ke ala koke e hiki ai iā ʻoe ke hoʻokū hou i ka tonometer a maʻamau i ʻole nā hopena koʻikoʻi. ʻO ka hapa nui o nā pilikia e kū mai i nā maʻi maʻi hypertensive aʻo ka lawe ʻana iā Noliprel e pili ana i ka mea ʻaʻole e lawe pono nā mea maʻi i nā papa, mai hahai i nā ʻōlelo hōʻike a ke kauka.

Hoʻomaopopo nā maʻi maʻi Hertertensive inā hiki iā Noliprel ke kūʻai aku i kēlā me kēia lāʻau kūʻai. Akā i kekahi manawa ʻaʻole kūʻai aku nā penikala. I kēia hihia, ʻae ʻia nā analogues. ʻO kekahi laʻana, Co-perineva, Prestarium, Perindopril a me Indapamide Forte, Co-prenes, Quinard, Mipril, Lysopres, Capotiazide, Iruzid. ʻO kahi mea hoʻokipa kūpono hoʻi ʻo ia ʻo Ena sandoz, kahi kūpono no ka mālamaʻana i ka hypertension pono, maʻi kūlohelohe o ka puʻuwai, a me ke pale ʻana o ka myocardial infarction.

Nā wikiō pili

Ua wehewehe kēia wikiō i ka hōʻola no ka hypertension Noliprel. E haʻi aku lākou i nā mea e kuhikuhi ʻia ai a ma nā ʻano hana:

No laila, ʻo kekahi o nā lāʻau lapaʻau antihypertensive kūikawā hou loa ʻo Noliprel. ʻO ka lāʻau lapaʻana akā lūlū koke i ka paʻakikī. Loaʻa i nā ʻano like ʻole. Mahalo i kēia, ʻoi aku ka maʻalahi ma ke koho i ka momona kūpono loa. Akā ʻaʻole hiki ke hoʻomaʻamaʻa iā ʻoe iho. Pono ke kauka e kuhikuhi i nā lāʻau lapaʻau a ma hope wale nō o ka hoʻopaʻa ʻana i ka mea maʻi.

Hoʻopau i nā kumu hoʻokaumaha o ke koʻikoʻi
Hoʻohālikelike i ke kaumaha ma loko o 10 mau minuke ma hope o ka lawelawe ʻana

Noliprel Forte: hoʻokumu a me ke ʻano o ka hoʻokuʻu

E hoʻolaʻa i ke koʻikoʻi, ua hoʻohana ʻia nā lāʻau lapaʻau o nā hopena like ʻole. Kūkuluʻo kēia, he diuretics - diuretics e hoʻoneʻe i ke kahe a me nā paʻakai sodium mai ke koko, hoʻemi i kona nui a hoʻomaikaʻi i ke kahe koko. Hoʻohui pū ʻia lākou me nā mea e ʻona ana kāna hana e pale i ka hana o ka enzyme e hoʻohuli ai i ka angiotensin I i ka angiotensin II.

Me ka hoʻohaʻahaʻa ʻana i ka pēpē, ua hana ʻia ka prorenin, ka mea, i ka wā e komo ai i ka plasma koko, i hoʻohuli ʻia i loko o renin, nakinaki i ka angiotensinogen, hana i ka angiotensin I. Hoʻāla ʻia kēia pūhui e ka angiotensin II i ka hana a nā kinemona o ke koko. I ka manawa like, lilo nā kīʻaha i ke koko, ua emi ka nui o ka puʻuwai, ka pūnaehana kūloko o ka puʻuwai, nona ke kuleana, e hauʻoli ana, e hana ʻia nā ald testosterone, e hoʻopaʻa ana i ka paʻakai a me ka wai, e hoʻonui hou ana i nā ukana ma ka hoʻolima. Ke neʻe pinepine nei kēia kaʻina hana e lawe hou i nā lāʻau antihypertensive.

Noliprel A Forte (Noliprel Forte) - kahi hana hou o ka hana hui pū ʻana: diuretic a me ka hana o ka neʻe o ka angiotensin-hoʻohuli i ka enzyme. Hoʻonui i nā pono o ka hopena, hoʻoemi i nā hopena ʻaoʻao a me nā hoʻopiʻi.

Loaʻa kēia lāʻau lapaʻau i kahi hoʻemi ʻana o nā mea hana i kapa ʻia i kapa ʻia ʻo Noliprel A. Hōʻike ʻia no nā maʻi no ka hiki ʻole ke hana i ka lāʻau lapaʻau me kahi hana hoʻoikaika.

Loaʻa i ka lāʻau lāʻau ʻelua mau mea ikaika:

indapamide (1.25 mg),
perindopril arginine (5 mg).

ʻO ka sodium carboxymethyl starch (2.7 mg),
silika (0.27 mg),
lactose e like me ka molekole (71.33 mg),
hale ʻaina pākia (0.45 mg),
maltodextrin (9 mg).

Hoʻohana ʻia ka lāʻau lapaʻau i ke ʻano o nā convex oval papa keʻokeʻo. Hoʻopili ʻia i loko o nā hue plastik me kahi dispenser a me ka uhi ʻana i ka wai hoʻomoʻi a 14 a 30 mau mauʻa.

Ka hana lapaʻau

ʻO Indapamide lāua ʻo Perindopril he mau lāʻau antihypertensive o nā hui like ʻole, akā ua hui pū ʻia me ka ʻoihana paʻakikī. Hoʻohui ʻia nā mea, hoʻomāhuahua i kēlā me kēia hana i ke ʻano, e kōkua ana i ka hōʻemi ʻana i ka dosage a hoʻēmi i nā hopena ʻaoʻao.

ʻO nā kolo i ka sulfonamides, he waiwai diuretic. Ma ka paleʻana i ka hoʻopili ʻana o nā papa sodium i loko o ke koko, e hoʻokuʻu koke iā lākou i nā lolo me ka plasma nui, hoʻonui i ka urination. Kēia hana hiki i ka wikiwiki ke hoʻohaʻahaʻa iki i ka kahe o ke kahe i loko o nā moku, hoʻomaikaʻi i ka kahe o ke koko, e hoʻolohi ana i ka puʻuwai.

ʻO ka Indapamide e hōʻemi i ka hikiʻole o nā pā vascular i ka hana o ka angiotensin II. Eia kekahi, hōʻemi ke kinona i ka hoʻoneʻe ʻana o ka calcium ma ke koko ma muli o kāna kāpae i ka pāʻai, e hōʻemi ana i ka% o kāna mau pūmua e komo ana i ka myocardial tissue.

ʻO ka calcium ka mea e kūleʻe i nā ʻōpū, ke alakaʻi nei i ka piʻi ʻana o ka puʻuwai a hoʻonui i ke kaumaha.

ʻO ka Indapamide e hōʻemi i ka hoʻonaninani o nā ʻimi manuahi o ka oxygen, kahi e waiho ai i ka wā lohi o ke kino a me ka hiʻohiʻona o nā neoplasms.

Hoʻopili koke ʻia ka waiwai i ka hoʻopili ʻana i nā protein plasma, ʻālamua elastin. Hoʻokuʻu ʻia ia i nā māka. Ma kahi o 30% e hoʻoneʻe ʻia e ka ate ma ke ʻano o nā metabolites a me ke ʻano mua.

Loaʻa i ka Indapamide kahi hopena hilinaʻi-dosis, no laila, ua kuhikuhi ʻia no ka papa o ka mālama ʻana.

Perindopril

ʻO kahi ʻāpana e pale i ka nānā ʻana o ka angiotensin II - kahi vasoconstrictor ikaika. Aia kekahi mau hopena ʻē aʻe e hoʻopiʻi maikaʻi ʻia ka mālama ʻana i nā ʻōnaehana koko.

ho'ēmi i ka hana ald testosterone,
hoʻonui i ka hana renin,
hōʻemi iki i ka puʻuwai naʻau ʻole ke hoʻololi nei i kā lākou mele.

Hoʻomaikaʻi ʻo Perindopril i ke kahe o ke koko, hoʻēmi i ka luhi ma ka ʻōpū puʻuwai, hōʻemi i ka hopena o ka hōʻeha ʻana o ka naʻau, pale i ka hoʻomohala ʻana o ka hyperplasia a i ʻole hypertrophy o ka ʻeha o ka puʻuwai, e kau nei i kahi hopena cardio- a me ka hopena angioprotective.

E hoʻohaʻahaʻa i ke koko, ua lawe ka waiwai i hoʻokahi manawa - ke hopena ka hopena ma hope o 4 mau hola a mau i kahi lā - a ʻo ka papa. Me ka hoʻohana o kēlā me kēia lā, hōʻike ʻia kahi hopena therapeutic ma hope o hoʻokahi mahina a hoʻomau i ka lōʻihi.

Ke noi nei no kahi manawa o 6 mau mahina a ʻoi paha ka nui o ka hoʻohaʻahaʻa ʻana i ka ukana ma luna o ka puʻuwai a me ke koko a hoʻonui i ke ahonui kino i nā poʻe maʻi me ka ʻehaʻeha naʻau. ʻAʻole addictive ke Perindopril.

Ke lawe ʻia, wikiwiki koke ʻia, palupalu a paʻa ʻia i nā kahe koko, me ka hoʻohuihui ʻia e ka ate, ka mea i hoʻopā ʻia e nā ʻōpū a me nā feces.

Hoʻomaopopo ʻia ka lāʻau lapaʻau no ka mālama ʻana i ka hypertension koʻikoʻi - kahi ʻōnaehana (3-4 mau manawa i ka lā) e hoʻonui i ka pehu ma luna o 140/90. Hoʻomaʻamaʻa pinepine ʻia nā maʻi i nā maʻi 35 35 mau makahiki a ʻaʻohe kumu kīnā ʻia.

ʻO ka hoʻokele mauʻana i ka lāʻau lapaʻau "Noliprel Forte" i nā manawa mua o ka maʻi hiki ke hoʻōla i ke kaumaha. Ma kahi hōʻeha nui, ke kolu o ka wā, i ka wā e piʻi ai ke koko i ka lā 180/110, mālama ia i kahi haʻahaʻa haʻahaʻa, e hōʻemi ana i ka hopena o ka hemorrhage a me ka puʻuwai puʻuwai.

Hōʻike ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana i nā mea maʻi me ka hypertension holomua me ka ʻano maʻamau diabetes type 2, i mea e pale ai i nā hōʻeha o nā maʻi hui.

Nā Paʻi Noliprel Forte

Ka maikaʻi loa ka lāʻau ma ka hakakā me ka hypertension. Ma muli o ka mana like o ka lāʻau, ka hui kūleʻa o nā mea nui (perindopril, indapamide), hiki i ka make o Noliprel ke hoʻololi i ke kahe o ke koko a hoʻohemo i ka nui o ka wai mai ke kino. ʻO ka hopena paʻa e ʻike ʻia ai ʻo Noliprel ma hope o nā hebedoma 3-4 mai ka hoʻomaka ʻana o ka hoʻōla ʻana a ʻaʻole i mālama ʻia e ka tachycardia. Hoʻomaopopo ʻia ka lāʻau lapaʻau no ka mālama ʻana i ka home, me ka mālama manawa wā ʻana e kekahi kauka i hoʻoponopono i ka dosage.

Ka hoʻokūkū o Noliprel

Loaʻa ka lāʻau lapaʻau ma nā papa keʻokeʻo oblong. He nui nā ʻano o Noliprel i loaʻa kahi ʻano like ʻole o nā mea nui: perindopril, indapamide. ʻO ka ka piha piha o ka lāʻau lapaʻau i hōʻike ʻia i ka papa ʻaina:

ʻO ka hoʻolikā Perindopril, ma mg

ʻO ka paʻa ʻana o ka indapamide, i loko o mg

lactose monohidate, microcrystalline cellulose, hydrophobic colloidal silicon, arginine (i waiho ʻia ma ka palapala hoʻokuʻu me ka wī prefix "A")

Noliprel A Bi-Forte

Noliprel A Forte

Ka hana lāʻau lapaʻau

ʻO ka lāʻau Noliprel ka mea hui pū i ʻelua mau mea nui i loaʻa i kā lākou mau waiwai a loaʻa nā hopena like ʻole.

Perindopril. Hoʻemi i ke kaʻe o ke koko i ka pae maʻamau, hoʻēmi i ka pale ʻana i nā kahe koko, hana i nā paia o nā ʻalala e ʻoi aku ka elastic, hoʻonāukiuki i ka ʻōpū o ka puʻuwai, hōʻemi i ka hypertrophy mai ka hema, a hōʻemi loa i ka ukana i hoʻopuka ʻia ma ka naʻau o ka naʻau.
Indapamide. Hoʻopau i nā kahe nui ma o nā keiki, kahi hopena diuretic a me nā vasoconstrictor.

Nā hōʻailona no ka hoʻohana ʻana

Hoʻohana ʻia nā papa no ke kaomi Noliprel no ka hōʻike wale nō no ka hoʻomau maʻi - pono (kumu mua) hypertension arterial. Hoʻopilikia ʻia kēia maʻi ma nā maʻi o ke kelepona thyroid. Eia naʻe, e like me nā ʻōlelo i hiki ke kuhikuhi ʻia ka lāʻau lapaʻau no nā kumu prophylactic no ka mālama ʻana i nā pathologies vascular i nā poʻe maʻi o nā hui kūikawā (kaumaha hypertension, type II diabetes mellitus).

Nā Kaukuhi Noliprel Forte

ʻO ka ʻaoʻao maikaʻi o ka lāʻau lapaʻau e pono e lawe ʻia i hoʻokahi lā i ka lā. He kūpono kēia no nā ʻelemakule, e hōʻeha pinepine nei i ka poina. ʻO ka manawa kūpono loa e lawe i ka lāʻau lapaʻau i ke kakahiaka. E hoʻopau ʻia nā papa ʻaʻa (mai nauʻa ʻole, mai hoʻokaʻawale iā ʻoe i ʻelua papaʻai) ma mua o ka ʻai, inu i nā wai he nui. Hōʻike ʻia ka hana o nā papa i 2-5 mau hola ma hope o ka hoʻohana a kū i 24 mau hola. Ma hope o hoʻokahi mahina a me kekahi hapa o ka lawe ʻana i ka lāʻau lapaʻau, hoʻoponopono ke kauka i ke ʻano.

I ka wā hāpai

Hoʻokuʻu piha ʻia ka hoʻohana ʻana i ka lāʻau Noliprel i ke kūlohelohe i ka wā keiki a me nā ʻōpiopio. Ke hoʻolālā ʻana a i ka wā hāpai paha, pono e hoʻokaʻawale ke ʻano antihypertensive. Hoʻokomo paha ka mea ikaika a Noliprel i ka hoʻopuka ʻana o ka pēpē, ka mea:

nā mālamalama maikaʻi ʻole
kahe
ho'ēmi i ka hana renal i ka pēpē,
lohi ma ka hoʻomohala ʻana i ka hanana fetalxicity,
lohi ana i ka hoʻokumu ʻana o nā iwi o ka ʻōpū o ke keiki,
haehae maʻi.

I ka wā hānai, pono e hoʻokuʻu ʻia ʻo Noliprel. ʻO nā māhele o ka lāʻau lapaʻau e hōʻemi i ka nui o ka waiū umauma a pale i nā lactation. Eia kekahi, hoʻopilikia ʻo Noliprel i ka olakino o ke pēpē, e hōʻeha ana i ka jaundice a i ʻole hypokalemia. Inā nui ka lāʻau lapaʻau no ke olakino o ka makuahine a ʻaʻohe mea e hoʻololi i ia mea, pono ke hoʻokaʻawale ʻia ke pēpē i kai kūlohelohe.

I ke wā kamaliʻi

ʻAʻole ʻōlelo ʻia ʻo Noliprel no ka mālama ʻana i nā keiki a me nā ʻōpio i lalo o 18 makahiki o kona mau makahiki. ʻAʻole ʻo ia ka hopena, nā hopena a me ka hopena o ka lāʻau lapaʻau ma ke kino o nā keiki. ʻO ka hōʻole ʻana i kēia contraindication hiki ke alakaʻi i ka palupalu i ke olakino a me ka hoʻokipa hoʻokipa hou e hoʻihoʻi i nā hōʻailona koʻikoʻi o ka mea maʻi.

Nā ʻōlelo a ke kūʻai a me ka waiho ʻana

Kūʻai ʻia ka lāʻau lapaʻau e ka lāʻau lapaʻau. ʻAʻohe mea mālama kūpono loa, pono ʻoe e mālama iā Noliprel i ka holo ʻana o nā keiki i kahi pālahalaha ʻaʻole i kiʻekiʻe aʻe ma mua o 30 degere. ʻOi aku ka ola o ka lāʻau lapaʻau ʻaʻole ʻoi aku ma mua o 3 mau makahiki.

Hāʻawi ʻia i ke kumu kūʻai nui o Nolirel a me kahi papa inoa o nā contraindications, hiki ke loli i ka lāʻau me nā analogues. ʻO ka hoʻoholo e koho i kahi pono hana e hōʻemi i ke neʻe koko, pono e hana ʻia e ke kauka. Hoʻohana ikaika ka hui pū ʻana o indapamide a me perindopril i loko o ia mau lāʻau.

Ko-Perineva,
Perindopril-Indapamide Richter,
Perindapam,
Co Parnawel
Perindid
Noliprel A
Indapamide Perindopril-Teva,
ʻIplelo Kahalewai
Iruzid,
Equator
Dalneva.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

ʻOiaʻiʻo, pono ke kanaka ponoʻī i kēia hihia, ʻoiai ke hilinaʻi nei ia i ka makahiki a me ke ʻano o ka mea maʻi, a me ka maʻi i hōʻike ʻia i loko ona. Eia naʻe, aia he mau la laulā i kuhikuhi ʻia a me nā rula kōkua. ʻOi aku ka maikaʻi o nā papa Noliprel i kakahiaka aʻe - ma kēia ala e piʻi koke ai ka hopena a lilo i ka lōʻihi o ke ʻano o ke ʻano o ka lā.

Me ka nui o ka ʻōlelo, ua ʻōlelo ʻia e nā pākeke e lawe i hoʻokahi papa i ka lā. Inā kūpono, ke kauka, ʻoiaʻiʻo, hiki ke hoʻololi i ka palena a i ʻole ka hoʻoponopono.

Keʻano "Noliprel forte": contraindications

Eia kekahi, hoʻopiʻi ʻoiʻi ʻaʻole pilikia a me hypokalemia i nā contraindications. ʻO nā mea maʻi me nā maʻi pūpū koʻikoʻi ua pāpā ʻia hoʻi. Aʻo kaʻoiaʻiʻo nō, ʻaʻole pono ke kauoha ʻia ka lāʻau no nā keiki ma lalo o ka makahiki 18. A no ka mea ʻo ka huahana ka lactose monohydrate, ʻaʻole ia i kuhikuhi no ka poʻe e maʻi ana i ka nele o ka lactose a me kekahi mau maʻi ʻē aʻe e pili ana i ka metabolism o ka maʻi o ka maʻi.

ʻO ia ke kumu hiki ʻole ʻoe e poina e hiki ke kuhikuhi ʻia kēia lāʻau lapaʻau e ka mea hele mai i ke kauka ma hope o ka loaʻa ʻana o nā hopena o nā hōʻike a me nā haʻawina. Inā loaʻa nā contraindications, ʻo nā hopena o ka hopena e hiki ke pilikia i ka olakino a hiki i ke ola.

Hiki paha nā hopena hoʻohālikelike

ʻO ka manawa, ke alakaʻi ʻia ka lāʻau lapaʻau i ka hana hewa ʻana o ka ʻōpū o ka ʻōpū - ka maloo maloʻo, bronchospasm, rhinorrhea e loaʻa mai. I nā hihia lohi, hiki i ka hoʻohana ʻana i ka lāʻau ke alakaʻi i ka angina pectoris, arrhythmias, stroke, hōʻeha ka puʻuwai, hoʻonā.

I kekahi manawa loaʻa ka paila, ka luaʻi, nā maʻi ʻaʻai, maloʻo maloʻo. Kēia loa, hoʻoulu ʻia ka hana e ka hoʻomohala ʻana o ka pancreatitis a i ʻole jaundice.

Hoike hōkeo

He mea kūpono ia e hoʻolilo i ka hopena mua o ka lāʻau i ka hōʻemi i ke kahe o ke koko - ʻaʻohe mea e makaʻu, hopohopo kēia, akā i nā lā mua. Akā ʻo kēlā mea maʻi e pono ma lalo o ka mālama mau o nā limahana lapaʻau.

Eia kekahi, pono e lawe i nā hoʻokolohua mai ka manawa i ka wā o ka ʻoihana - ke kōkua nei ia e nānā i ke kiʻekiʻe o ka creatinine a me ka pāhana i loko o ke koko, no ka mea, i nā neʻe mai ke ʻano maʻamau i hiki ai ma lalo o ka mana o ka lāʻau lapaʻau.

ʻAʻole ʻōlelo nā kauka i ka holo ʻana i ka wā ʻo ka lapaʻau, hana me nā ʻano hana like ʻole e pono ai ka naʻau kiʻekiʻe loa a me ka wikiwiki wikiwiki. Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, e maopopo e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āu e lawe ai, e like me ka lāʻau ʻo Noliprel Forte i hui pū ʻia me nā lāʻau lapaʻau ʻē aʻe.

Nā Hōʻike Manaʻo Mea kūʻai

Ma kekahiʻaoʻao, loaʻa i nā lāʻau "Noliprel forte" kekahi mau hemahema. E hoʻomaka me ka mea, he mea kūpono ʻole i kāna kumukūʻai - ʻaʻole kūpono kēia kumukūʻai no ka poʻe āpau, ʻoiai inā hiki ke hele mai i ka lāʻau lōʻihi. Eia kekahi, ʻo kekahi mau mea maʻi i lawe i ka lāʻau lapaʻau no ka manawa lōʻihi (2-3 mau mahina) i hoʻomohala i kahi ʻaoʻao maikaʻi ʻole maikaʻi ʻole - hōʻemi ka lauoho. Ma mua o kēlā mau hōʻino, pono ʻoe e ʻimi pinepine i ke kauka: pono paha ʻoe i kahi analogue o Noliprel (no ka laʻana, ʻo Enap N). Ma ke ala, hiki iā ʻoe ke kūʻai aku i nā huahana e loaʻa i nā mea hoʻoikaika nui o ka lāʻau (perindopril a me ka indapamide) - e lawe aku ana iā lākou e kōkua i ka hopena o ka hopena like, akā e emi iki ka loaʻa ʻana o ka maʻi bald.

Huaʻa noho hoʻoponopono

Hoʻomaopopo ʻia e lawe i ka lāʻau lapaʻau 1 papa i ke kakahiaka ma mua o ka ʻaina kakahiaka. Hoʻokomo wale i kahi wai hoʻokahi no Noliprel Forte e mālama i kahi hopena therapeutic i loko o ke ao.

ʻO nā mea maʻi me ka maʻi mellitus no ka maʻi, ka palaka a i ʻole ka maʻi hepatic e hōʻike ʻia e hoʻomaka ai i ka maʻi me ka lāʻau "Noliprel A".

ʻO ka dosis kūpono a me nā ʻōlelo aʻoaʻo no ka lawe ʻana i ka lāʻau lapaʻau e hāʻawi ʻia e ke kauka hele mai. Inā hahai ʻia nā ʻōkuhi a pau, ʻoi loa ka hopena o nā hoʻopiʻi a me nā hopena ʻino loa, a ʻo ka nui o ka mālama ʻana he lōʻihi.

I kekahi mau hihia, inā hiki ʻole ke koho i kahi papaʻaina, ua hoʻololi ʻia ka lāʻau i ka lāʻau monocomponent a me ka indapamide a me ka perindopril i kuhikuhi ʻia i nā pae pākahi.

Nā hopena maikaʻiʻole

ʻAʻole pono ka hopena maikaʻi o ke kino me ka hana ʻōnaehana. Inā hoʻololi ka kūlana i kahi pilikia ʻole a i ʻole ka weliweli i ke ola a me ke olakino, e maopopo e hōʻike i kāu kauka. Hoʻoponopono ʻo ia i ka dosage a hoʻololi paha i ka lāʻau lapaʻau.

ʻO nā ʻōhumu maʻamau o nā maʻi:

ʻeha ka ʻōpū, hoʻopā,
nā hōʻike waho o nā pāluki - hyperemia, urticaria, itching, peeling,
ke hiʻohiʻona o ka tinnitus, nā hiʻohiʻona ʻike maka.
ka hopena i ka hopena orthostatic hypotension ka hopena ʻē aʻe,
mahuahua ka maloo o ka ʻākī i ka waha a me ka ʻāʻī, pāā,
nāwaliwali ākea, nā ʻōpū polu.

ʻO nā haʻalulu e like me ka hiamoe hoʻomaha, arrhythmia, tachycardia, edema, ke ʻano o nā hopena aler i ka maʻi nui, ʻo ka hoʻonui nui ʻana ka mea maʻamau.

Ma muli o nā loli i ke kahe o ke koko, hiki i ka lāʻau lapaʻau ke hoʻopilikia i ka hana o nā ʻāpana kūʻokoʻa. No laila ua kauoha ʻia nā hoʻokolohua maʻamau o kāna palapala.

ʻO ka lāʻau "Noliprel Forte" kahi mea i hōʻike i ka hopena therapeutic i ka mālamaʻana i ka hypertension pono.

I ka poʻe maʻi e lawe ana i ka lāʻau lapaʻau, ua hoʻomaopopo ʻia

hopena paʻa ma hope o 2-3 mau pule o ka hoʻokele ʻana,
hōʻemi ma ka nui o ka hypertrophied hema ventricle,
ka holomua o ke kūlana maʻamau a me ka maikaʻi.
ka hoʻopauʻana i ka kaila o ke koko i ka mālamaʻana i ka hoʻomaka mua o ka maʻi hypertension.

Ma keʻano holoʻokoʻa, maʻalahi ka ʻae ʻia o Noliprel, a ma kahi o ka intolerance e pani ʻia ai e kekahi lāʻau lapaʻau hou o kahi hana like.

Hiki iā ʻoe ke kūʻai i ka lāʻau ma ka hale kūʻai. Hoʻokuʻu ʻia wale ia ma ke kau ʻana. ʻAe ʻia ka ʻae ʻana ma hope o ke kūkā ʻana me ke loea. ʻO ka kumukūʻai kumukūʻai o kahi lāʻau lapaʻau he 680 mau rubles no ka pā o 30 mau pcs.