ʻO nā hopena kūpono no ka mālamaʻana i ka maʻi diabetes 2 type
Pono ka poʻe i ka hoʻohana i nā peni hypoglycemic no ka maʻi maʻamau o ka lā 2, kahi papa inoa o kahi hanauna hou e hoʻopaneʻe ʻia i kēlā me kēia makahiki me nā loli hou. Inā hoʻomaka ka hōʻailona o ka "maʻi koko" a me ka pae o ka glucose i ka ʻaina a me ka hana kino, a laila hiki ke hoʻonui ʻia nā mālama o ke kino, ʻaʻole hiki ke hoʻokau i ka pilikia ma kāna iho.
Pono e hoʻomanaʻo ʻia he ʻelua mauʻano o ka maʻi maʻi - ka hilinaʻi-like me ka non-insulin-hilinaʻi. Ma ka lua o nā hihia, me kahi papa lōʻihi o ka pathology, hoʻomaka nā maʻi homaʻi e hoʻohana i nā lāʻau lapaʻau e ʻāpono ana i ka pale ʻana i ka insulin.
Ke hōʻike nei ka mākeke pharmacological i kahi nui o nā lāʻau lapaʻau e hoʻohiolo ai i ke kō, akā ʻo kēlā me kēia mea he ʻano hana kūikawā o ka hana, contraindications a me nā hopena maikaʻi ʻole. E noʻonoʻo i nā ʻano nui o nā lāʻau lapaʻaka hypoglycemic.
ʻO nā ʻano nui o nā lāʻau lapaʻau no ka maʻi diabetes type 2
ʻO ka hoʻolālāʻana o ka maʻi maʻi type 1 e pili nui loa me kahi maʻi autoimmune. Ma kēia hihia, ua huehue ka hana o ka pancreas, ma muli o ka hopena o nā keʻena beta o ka isletus i nā mea aʻokiʻoki i ka mea e hoʻōla ai i ka hormone hoʻohaʻahaʻa - ka insulin. ʻAʻole like me ka mea mua, me ke ʻano type diabetes 2, ʻaʻole e pau ka hana ʻana i ka hormone. Pili ka pilikia i ka maʻa ʻana o nā receptors cell e hoʻomaopopo i ka insulin.
Hoʻokomo ʻia ka lua o ke ʻano o ka papa no 90% o nā maʻi āpau. ʻO ka pinepine he poʻe ka mea ma luna o 40-45 ka poʻe i paʻi i ka momona a i ʻole ka ʻohana pili me ka maʻi maʻi (genetic factor).
Ma ka 2017, nui nā lāʻau lapaʻau e hōʻemi i ka glucose i hoʻomohala ʻia a holomua. I kēia lā, aia nā ʻano o nā mea hoʻonā hypoglycemic āpau.
Hoʻoulu i ka hoʻoliʻiliʻi ʻana o nā cell:
- thiazolidinediones (Pioglar and Diaglitazone),
- ʻo Biguanides (metformin).
ʻO nā lāʻau hou hou i hoʻomaka e hana ʻia ma ka 2000s:
- Nā papa inoa DPP-4 (Ongliza a me Yanuviya),
- alpha glucosidase inhibitors (Glucobai),
- ʻO agonist receptor GLP-1 (Viktoza lāua ʻo Baeta).
He mea hoʻonāukiuki o Hormone:
- ʻo ka meglitinides (Starlix a me Novonorm),
- kaila ʻaila sulfonylurea (Maninyl, Glurenorm a me Diabeton).
ʻO ke kolu o nā lāʻau lapaʻau e hoʻopilikia kino i ka hana pancreatic a hoʻoheheʻe ʻia ia. Ke lawe nei i kēia mau lāʻau lapaʻau, aneane pinepine ke manawa o ka hoʻololi o ke ʻano maʻi diabetes type 2 i ka mea mua.
ʻO nā lāʻau lapaʻau i ʻōlelo ʻia ma mua no ka mālama ʻana i nā maʻi diabetes type 2 ua manaʻo ʻia he ʻano hou o nā lāʻau lapaʻau, ka ʻike kikoʻī e pili ana i ka mea e hōʻike ʻia ma hope.
Nā hiʻohiʻona o ke kuhikuhi ʻana i nā lāʻau lapaʻau maʻi
ʻO ka mea mua, hāʻawi ʻia ka makemake i nā lāʻau lapaʻau me ka liʻiliʻi ʻokoʻa o ka hypoglycemia: biguanides, gliptins, incretins. ^ E Ha yM. Inā pilikia ke kanaka mai ka momona a me ke hypertension, ʻoi aku ka maikaʻi o nā incretins - ʻae lākou iā ʻoe e hōʻemi i ke kaumaha a hoʻoponopono i ke kaomi.
Kahi no ka hoʻonoho ʻana o nā biguanides: ʻo ka inumua mua o metformin ʻo 500 mg 2-3 mau manawa i ka lā ma hope o ka papaʻaina. ʻO ka hoʻonui ʻia ʻana ma lalo he 2 paha ma hope o ka hoʻomaka ʻana o ka lāʻau. Pono ka nui o ka nui o ka lā ma mua o kēia lāʻau lapaʻau ma mua o 3000 mg. Hoʻonui ka hoʻouluʻana i ka hopena me nā liʻiliʻi liʻiliʻi mai ka gastrointestinal tract.
Hoʻopuka: ʻO nā lāʻau lapaʻau no ka maʻi maʻi o ka hanauna hope loa, ua lawe ʻia 1 papa (25 mg) i kēlā me kēia lā, ʻaʻohe kumu o ka ʻai.
Holoi lāʻau hōʻike ʻia o kēia pūʻulu i hōʻike ʻia ma ke ʻano o nā hopena o ka hoʻonā. Hoʻohana ʻia lākou ma ka 1 a i ʻole 2 mau manawa i ka lā, e pili ana i ka hanauna.
Inā hāʻawi mai ka monotherapy i nā hopena maikaʻi ʻole, e hoʻohana ʻia nā hui like ʻole o nā mea maʻi hypoglycemic:
- Metformin + Gliptins.
- Nā Incretins + metformin.
- Hoʻomākaukau Metformin + sulfonylurea.
- ʻO Glinides + metformin.
ʻO nā hui mua ʻelua me ka liʻiliʻi liʻiliʻi o ka hypoglycemia, ke kau nei ka paona ma luna o lākou.
Kahi no ka hoʻonoho ʻana i ka hoʻomākaukau ʻana i ka sulfonylurea: ke hilinaʻi ia i ka hanauna o ka lāʻau. Lawe ʻia nā lāʻau lapaʻau 1 mau manawa i kēlā me kēia lā i ke kakahiaka. Me ka hoʻonui ʻana o ka dosage, hiki ke hoʻokaʻawale ʻia nā ʻano kumu i ke kakahiaka a me ke ahiahi.
Hoʻolālā kulana hoʻōla: ʻO kahi hiʻohiʻona o ka hoʻohana ʻana i kēia mau lāʻau lapaʻau ka mea pono i nā lāʻau o kēia pūʻulu o ka paʻa ʻana i ka ʻaʻai meaʻai a lawe koke i mua o lākou. ʻO nā papa maʻa mau i nā manawa 3 i ka lā.
ʻO nā mea hōʻike iā Alpha Glucosidase: ka ʻike pono ʻana o ka lawe ʻana i nā lāʻau lapaʻau inā pono ʻoe e lawe i nā papa i mua o ka papaʻaina. ʻO ka inanua mua o 50 mg ka inu i mau manawa 3 i ka lā. ʻO ka awelika helu lā maʻamau he 300 mg. ʻO ka 200 maximum ka nui o ka manawa i ka lā. Inā pono, e hoʻonui i ka paona ma hope o 4-8 mau pule.
Kaumakaiwa: Lawe ʻia nā lāʻau lapaʻau i nā manawa 1-2 i ka lā, e pili ana i ka hanauna. ʻAʻole ke pili i ka manawa kai i ko lākou hopena. Inā kūpono, hoʻonui i ka dosage, e hoʻonui ma hope o 1-2 mau mahina.
Ka papa inoa o nā lāʻau lapaʻau haʻahaʻa
Koho ke kauka i kekahi mau pūʻulu o nā lāʻau lapaʻau, me ka noʻonoʻo ʻana i nā ʻano pilikino hoʻokahi o ke kanaka: nā maʻi hoʻohui, ka loaʻa ʻana o ke kaumaha nui, nā pilikia me ka CVS, ka meaʻai, etc.
Nā lāʻau lapaʻau | Inoa kālepa | Mea hana | ʻO ka nui loa dosage, mg |
Biguanides | Siofor | Berlin Chemie, Kelemānia | 1000 |
Sulfonylureas | Diabeton | Labourie Labourie, Farani | 60 |
Amaril | Sanofi Aventis, Kelemānia | 4 | |
Kuiluna | Beringer Ingelheim International, Kelemānia | 30 | |
ʻO ka puʻuwai ʻo Glibenez | Pfizer, Farani | 10 | |
Maninil | Berlin Chemie, Kelemānia | 5 mg | |
Nā ʻōwili | Baeta | ʻO Eli Lilly lāua ʻo Kamupani, Switzerland | 250 mcg / ml |
Victoza | ʻO Novo Nordisk, Denemaka | 6 mg / ml | |
Hoʻohui inoa | Januvia | Merck Sharp a me Dome B.V., Netherlands | 100 |
Galvus | ʻO Novartis Pharma, Switzerland | 50 | |
Onglisa | AstraZeneca, UK | 5 | |
Trazenta | Beringer Ingelheim International, Kelemānia | 5 | |
Vipidia | Kauwe Pūnaewele ʻo Takeda, USA | 25 | |
ʻO nā mea hoʻonani alpha Glucosidase | Hoʻopuka | Bayer, Kelemānia | 100 |
Nā Hoʻopiha | NovoNorm | ʻO Novo Nordisk, Denemaka | 2 |
Starlix | ʻO Novartis Pharma, Switzerland | 180 | |
Thiazolidinediones | ʻĀina Pioglar | ʻOihana, San India Pharmaceutical, India | 30 |
Avandia | Palapala GlaxoSmithKline, Sepania | 8 |
I waena o nā lāʻau āpau a kēia pūʻulu, ʻo nā derivatives o ka methylbiguanide, metformin, i loaʻa ka mea kaulana loa. Hāʻawi ʻia nā hana hoʻokalakupua i ke ʻano o ka emi ʻana o ka hana glucose i ka ʻāʻī a me ke emi ʻana o ka pale ʻana o ka insulin e ka ioʻi ʻana a me nā ʻiʻo adipose.
ʻO ka mea hana pono a ka metformin. Hoʻomoe a pili iā ia:
- Merifatin,
- Formin lōʻihi
- ʻO Glyformin
- Diaspora
- Hopu,
- Siofor
- Diaformin.
- mai hoʻopilikia a hōʻemi paha i ke paona kino,
- hiki ke hoʻohui pū me nā hana papa ʻē aʻe o nā mea hypoglycemic agents,
- aia ka pilikia haʻahaʻa o ka hypoglycemia,
- mai hoʻonui i ka hoʻonui ʻia ʻana o kou ʻaihue,
- hoʻemi i ka pilikia o kekahi mau maʻi cardiovascular,
- hoʻolohi a pale i ka hoʻomohala ʻana o ka maʻi diabetes i ka poʻe me ka pākīa o nā ʻaihā.
- uku.
- pinepine nā hopena ʻaoʻao mai ka gastrointestinal tract, no laila, ua kuhikuhi mua ia i nā haʻahaʻa haʻahaʻa,
- kumu i lactic acidosis.
- E hoʻokō me ka meaʻai haʻahaʻa-haʻahaʻa (emi iho ma lalo o 1000 kcal i hoʻokahi lā).
- Allergic reaksi a pau o kekahi o nā mea.
- ʻO nā pilikia ʻeha, e komo me ka waiʻona.
- ʻO nā hiʻohiʻona hopena o ka renal a me ka palaualelo ʻole.
- ʻO ka wā hāpai.
- Nā makahiki o nā keiki a hiki i 10 mau makahiki.
Sulfonylureas
ʻO ka ʻoihana nui o ka hana ka mea e hoʻoulu ai i ka ʻikepili ʻana o ka insulin. ʻO nā mea waiwai a me nā lāʻau lapaʻau no ka maʻi maʻamau o 2 o kēia hui.
- Gliclazide. ^ E Ha yM. Nā inoa kalepa: Golda MV, Gliclad, Diabetalong, Glidiab. Kauʻai Diabeton MV, Diabefarm, Diabinax.
- Glimepiride: Instolit, Glaim, Diamerid, Amaril, Meglimid.
- Glycidone: Yuglin, Glurenorm.
- Hoʻolālā: Mālama ʻO Glibenez.
- ʻO Glibenclamide: Statiglin, Maninil, Glibeks, Glimidstad.
Loaʻa kekahi mau lāʻau lapaʻau i ka hana lōʻihi - i kapa ʻia ʻo MV (hoʻokuʻu ʻia) a i ʻole retard. Hana ʻia kēia i mea e hōʻemi ai i ka nui o nā lāʻau i kēlā me kēia lā. No ka laʻana, Glidiab MV he 30 mg o ka waiwai a lawe ʻia hoʻokahi manawa i ka lā, ʻoiai inā e hoʻonui ka nui, a me ka maʻamau ʻo Glidiab - 80 mg, lawe ʻia ka hoʻokipa i ke kakahiaka a me ke ahiahi.
ʻO nā mea pono nui o ka pūʻulu.
- wikiwiki
- hōʻemi i ka hopena o ka hoʻopiʻi vascular o ka maʻi maʻamau o 2,
- uku.
- ka hopena o ka hypoglycemia,
- hiki ke hoʻohana ʻia ke kino iā lākou - hoʻomohala hou,
- nui paha e hoʻonui i ke kaupaona kino,
- hiki i ka pilikia no nā pilikia me ka ʻōnaehana cardiovascular.
- ʻAno maʻi type 1
- nā makahiki o nā keiki
- hapai a lactation
- allergy to sulfonamides and sulfonylureas,
- maʻi maʻi gastrointestinal
- ketoacidosis, maʻi maʻi precoma a me ka coma.
ʻO kēia ka inoa maʻamau no nā hormone e hoʻoulu i ka hana o ka insulin. Hoʻopili kēia me ka pankide-like pfide-1 (GLP-1) a me ka glucose-dependotio glucose-hilinaʻi, (HIP). Hoʻokomo ʻia nā incretins Endogenous (proprietary) i loko o ka digestive tract e pane ai i kaʻai o ka meaʻai a hana wale nō i nā minuke wale nō. No ka poʻe me ka maʻi diabetes, ua hana ʻia nā exogenous (hele mai waho) waho o nā mea i hoʻoulu ʻia, kahi hana lōʻihi.
ʻO nā hana o ka hana o ka peptide like-glucagon - 1 agonists receptor:
- Hoʻopilikia-kūlike i ka maʻi o ka insulin.
- Hoʻemi ka hoʻohuihui glucagon.
- Hoʻemi ka hoʻoneʻe glucose e ka ate.
- Hōʻalo mālie ka ʻōpū ʻai i ka ʻōpū ma mua, e hoʻopiʻi i ka hōʻemi o ka meaʻai a me ke kaumaha.
ʻO nā mea kanu a me nā lāʻau lapaʻau e hoʻohālike i ka hopena o GLP-1:
- Exenatide: Byeta.
- Kuhiihoi: Victoza, Saxenda.
- loaʻa i nā hopena like ʻole e like me kā lākou iho GLP-1,
- e kū'ē ana i ke kūlana o ke noi, ua emi ke kau o ke kino,
- Hoʻemi ka glycated hemoglobin.
- ʻaʻohe papa hoʻopiʻi, ʻike ʻia ka lāʻau lapaʻau,
- kaumaha koʻikoʻi hypoglycemia,
- nā hopena maʻamau mai ka gastrointestinal tract,
- uku.
- ʻAno maʻi type 1
- hapai a lactation
- ka pilikino ʻana o kēlā me kēia o nā ʻāpana,
- nā makahiki o nā keiki.
ʻEpekema, ua kapa ʻia ʻo IDPP-4 a i ʻole type 4 dipeptidyl peptidase inhibitors. No loko o ka hui o ka incretins, akā maikaʻi lākou. Hoʻoholo ka ka hana o ka hana e ka wikiwiki o ka hana ʻana i kāna kū ponoʻenehana gastrointestinal, ka mea e hoʻoulu ai i ke ʻano o ka insulin i loko o ka pancreas e like me ka neʻe o ke kō. Hoʻomaka lākou i ka hoʻoneʻe ʻana i ka glucose a hoʻoneʻe i ka hana glucose e ka ate.
Aia kekahi mau mea a me kā lākou hoʻomākaukau:
- Sitagliptin: Januvius, Yasitara, Xelevia.
- Vildagliptin: Galvus.
- Saxagliptin: Onglisa.
- Linagliptin: Trazenta.
- Alogliptin: Vipidia.
- haʻahaʻa haʻahaʻa o hypoglycemia,
- ʻaʻole e pili i ke kaumaha kino,
- hoʻoikaika i ka hoʻoponopono hou o ka ʻāpana pancreatic, kahi e hiki ai i ka lolo ke holomua ka neʻe ʻana o ka neʻe ʻana,
- loaʻa i ka palapala papa.
- ʻaʻohe data palekana palekana me ka hoʻohana ʻana i ka wā lōʻihi,
- uku.
- ʻO ka wā hāpai a me ka lactation.
- ʻAno maʻi type 1.
- Maʻi molaʻi.
- Nā makahiki o nā keiki.
ʻO nā mea hoʻonani alpha Glucosidase
ʻO ka hana nui o ka hana ka ka hoʻolohi ʻana i ka nalo ʻana o nā hāmeʻa i loko o ka ʻōpū. Hoʻololi ka mea i ka hana o nā enzymes e kuleana ai no ka ʻokiʻoki ʻana i nā disaccharides a me oligosaccharides i ka glucose a me ka fructose i ka lumen o ka ʻawaʻī liʻiliʻi. Eia kekahi, ʻaʻole lākou e pili i nā peka pancreatic.
Aia pū i kēia hui nā ʻāpana acarbose, kahi ʻāpana o ka lāʻau Glucobay.
Hoʻohui ʻia o ka lāʻau lapaʻau:
- aole e hoopilikia i ka paona,
- pilikia haʻahaʻa o ka hypoglycemia,
- ho'ēmi i ka hopena o ka hoʻomohala ʻana i nā maʻi diabetes type 2 i ka poʻe me ka hoʻomanawanui i ka hoʻohaʻahaʻa glucose.
- ho'ēmi i ka hōʻemi o nā pilikia kipi.
- nā hopena maʻamau mai ka gastrointestinal tract,
- ka hoʻohaʻahaʻa haʻahaʻa ma mua o nā mea hana waha hypoglycemic waha,
- kiʻi pinepine - 3 mau manawa i ka lā.
- ʻO ka wā hāpai a me ka lactation.
- Nā makahiki o nā keiki.
- Allergic reaksi a i kekahi o nā mea o ka lāʻau.
- ʻO nā maʻi pīpī.
- ʻO ke ʻano paʻakikī o ka wehe ʻole ʻana.
ʻO ka hana nui o ka hana ka hoʻoulu ʻana i ka hana hana i ka insulin. ʻAʻole ia e like me nā mau lāʻau lapaʻau ʻē aʻe, e hoʻonā lākou i ka mea huna o ka insulin i ka 15 mau minuke mua o ka ʻai ʻana, ma muli o ia i ke ʻano o nā "pīpī." Hoʻi hou ʻia ka manaʻo o ka hormone ponoʻī i kona waiwai kū i ka hola 3-4 ma hope o ka pau loa.
ʻO nā mea nui a me nā mea lapaʻau e:
- Hoʻokomo ʻo. ^ E Ha yM. Nā inoa kalepa: Iglinid, Diclinid, NovoNorm.
- Nateglinide: Starlix.
- ka wikiwiki o ka hana i ka hoʻomaka ʻana o ka maʻi,
- ka pono o ka hoʻohana 'ana e nā kānaka i ka' ōlelo kūpono ʻole,
- kaohi ʻana o ka hyperglycemia postprandial - i ka manawa e piʻi ai ke kiʻekiʻe o ke kōʻai koko ma hope o kahi kīʻaha maʻamau ma 10 mmol / l a i ʻole.
- loaʻa ka paona
- ʻAʻole paʻa ka palekana o nā lāʻau lapaʻau me ka hoʻohana mau ʻana,
- ka maʻa o ka hoʻohana 'ia me ka nui o nā' ai,
- uku.
- nā keiki a me ke senile
- ka wā hapai a me ka umauma.
- ʻAno maʻi type 1
- maʻi ketoacidosis maʻi.
Thiazolidinediones
ʻO glitazone kā lākou inoa inoa. Kūkulu lākou o nā mea hoʻonaninani - hoʻonui lākou i ka hiki ke hoʻopili ʻana i nā ʻine i ka insulin, ʻo ia hoʻi, a hōʻemi ʻia ka pale o ka insulin. ʻO ka hana o ka hana e hoʻonui ai i ka hoʻohana ʻana o glucose i loko o ka ate. ʻAʻole i like me derivatives sulfonylurea, ʻaʻole kēia mau lāʻau e hoʻoikaika i ka hana ʻana o nā poli pancreatic beta e ka insulin.
ʻO nā mea nui a me kā lākou hoʻomākaukau.
- Pioglitazone. ^ E Ha yM. Nā inoa kalepa: Pioglar, Diab-Norm, Amalvia, Diaglitazone, Astrozone, Pioglit.
- Rosiglitazone: Avandia.
- hōʻemi iki i nā maʻi macrovascular komplications,
- haʻahaʻa haʻahaʻa o hypoglycemia,
- ka palekana pale mai nā beta beta o nā pancreas,
- ho'ēmi i ka hopena o ka hoʻomohala ʻana i nā maʻi diabetes type 2 i ka poʻe i hoʻokumu mua ʻia iā ia.
- ho'ēmi i ka triglycerides a hoʻonui i nā lipoproteins kiʻekiʻe ma ke koko.
- loaʻa ka paona
- ka ulu ʻana o nā pākuʻi ma hope loa.
- hoonui ka ulu ʻana o nā iwi tubular i ka wahine,
- e lohi koke ka hopena
- uku.
- maʻi ate
- ʻAno maʻi type 1
- maʻi maʻamau ketoacidosis,
- ka wā hapai a me ka umauma.
- hōʻeha paʻa ka naʻau
- nā makahiki o nā keiki
- edema o kekahi kumu.
ʻO ka insulin diabetes type 2
Ke ho'āʻo nei lākou ʻaʻole e kākau i ka hoʻomākaukau ʻana i ka insulin i ka mea hope loa - ma ka manawa mua i mālama ai lākou i ka hana papa. Akā, i kekahi manawa nui nā inikini insulin e pono ai i ka hoʻomaka ʻana o ka lāʻau.
- ʻO ka ʻike mua o ka maʻi diabetes 2 2, i ka manawa o ka helu o ka hemoglobin glycated> 9% a hōʻike i nā hōʻailona o ka decompensation.
- ʻO ka nele o ka hopena inā e kuhikuhi ana i ka nui loa o nā mehana i loaʻa i nā lāʻau i loaʻa i ka wai kōkō.
- ʻO ka heleʻana o nā contraindications a me nā hua ʻōlelo hopena mai nā papa.
- Ketoacidosis.
- Aia kahi hoʻololi lōlō ke kali nei ke nānā ʻana i kekahi kanaka a i ʻole ka hoʻēmi ʻana i kekahi mau maʻi maʻi i loaʻa mai kahi hiki ke hoʻēmi ʻia ka metabolism.
- ʻŌpū (ma nā hihia he nui).
ʻO ka lāʻau antihypertensive
ʻO ke hypertension pūlima me ka maʻi diabetes i kahi ʻano hoʻopihapiha maoli - maikaʻiʻole ka hopena o ka hōʻeha ʻana o ka naʻau, nā hōʻeha, ka makapō a me nā hoʻopiʻi ʻē aʻe. No ka hōʻemiʻana i ka hopena o kā lākou uluʻana, hoʻomaka nā maʻi maʻi maʻi e kiaʻi pono i ko lākou lolo ma mua o nā mea ʻē aʻe.
Nā hui Antihypertensive:
- Nā mea ʻokoʻa paleka saluran kalepa.
- ACE paleai.
- Diuretics.
- Nā māka hua Beta.
- ʻO nā mea ʻihi ʻauhau ʻāhewa ala Angiotensin-II.
I ka hapanui pinepine, me ke ʻano maʻi type 2, ua kauoha ʻia nā inhibitions ACE.Pae pū kekahi hui:
ʻO lākou kahi mau o nā mea e kōkua i ka lipoproteins haʻahaʻa haʻahaʻa a me ke kolamu o ke koko. Nui nā hanauna o nā statins:
- Lovastatin, Simvastatin, Pravastatin.
- Fluvastatin
- Atorvastatin.
- Pitavastatin, Rosuvastatin.
Nā lāʻau lapaʻau, ʻo ka mea ikaika o ia e atorvastatin:
E pili ana i rosuvastatin:
Nā hopena maikaʻi o nā statins:
- I ka pale ʻana i nā kahe koko.
- ʻO ka hoʻomaikaʻi ʻana i ke ʻano o ka lula i loko o nā kīʻaha koko.
- ʻO ka pilikia o ke kūkuluʻana i nā hoʻopiʻi ischemic, myocardial infarction, stroke a me ka make ma muli o lākou ua hōʻemi ʻia.
Alpha Lipoic (Thioctic) Acid
ʻO ia kahi mea metabolic a me ka endogenous antioxidant. Hoʻohana ia e hoʻoponopono i ka lipid a me ka metabolism, ʻo ka hoʻowalewale i ka protein metabolism. Hāʻawi ka mea hoʻemi i ka hōʻemi o ka glucose i ke koko, hoʻonui i ka glycogen i loko o ka ate a pale i ka kū ʻana o ka insulin.
E pili ana nā lāʻau lapaʻau e pili ana i kēia mau hopena maikaʻi aʻe:
- Hepatoprotective.
- ʻO ka hypolipidemic.
- Nā Hypocholesterolemic.
- ʻOgogogia.
- Hoʻoulu ke ʻano o nā neurons.
Loaʻa nā lāʻau lapaʻau Thioctic acid i nā ʻano like ʻole a hoʻokuʻu i nā ʻano. ʻO kekahi mau inoa kālepa:
Lawe ʻo ka Diabetics i kēia mau lāʻau lapaʻau no polyneuropathy - lilo ka huhū ma muli o ka hanaʻino i ka hopena o nā nerve, nui loa i nā wāwae.
Neuroprotectors
ʻO neuroprotectors ka hui pū ʻana o kekahi mau pūʻulu o nā mea nona ka pahuhopu e pale i nā lolo neurons mai ka pōʻino, hiki nō iā lākou ke hoʻopiha maikaʻi i ka metabolism, hoʻomaikaʻi ʻana i ka lako o nā puʻuwai o nā nerve a pale iā lākou mai nā mea kūwaho.
- Nootropics.
- Antioxidants.
- Adaptogens.
- ʻO nā mea kanu o ka mea kanu.
Ke hoʻohana ʻia nā lāʻau lapaʻau o kēia mau poʻe e nā kānaka me ka maʻi diabetes type 2, kahi i ʻike ʻia ai ka maʻi diabetes a hypoglycemic encephalopathy paha. Hōʻike nā maʻi ma muli o nā maʻi metabolic a me nā vascular ma muli o ka maʻi maʻi.
ʻO ke aha lā ma ka maʻi diabetes 2
ʻO ka maʻi diabetes type 2 kahi maʻi endocrine i kahi e hana hewa ai i ka hoʻowalewale i ka hana o ka insulin e loaʻa ana i loko o nā lau o ke kino. ʻO ka huahana kiʻekiʻe o ka pancreatic β-cell i hoʻonāukiuki ʻia e ka maʻi e hōʻemi ai i ke kumuwaiwai o nā selela, e hoʻomaka ana ka emi ʻana o ka hana insulin, ke alakaʻi nei i ka pono o kāna huakaʻi. Hoʻomaka pinepine ka maʻi ma hope o nā makahiki 40. Hoʻomaka ʻia ka hoʻomaka ʻana o ka maʻi e nā maʻi o ka maʻi intravital wale nō a ʻaʻole ia e hilinaʻi i ka pilikia genetic. ʻO ka hapa nui o nā poʻe maʻi he piʻi ka nui o ka piʻina kūloko.
Hoʻomaopopo ka maʻi maʻi i kēlā mau maʻi i ka mālama ʻana i ke kumu o ka hoʻomaka ʻana o ka maʻi he kuleana koʻikoʻi. E kū'ē i ke ʻano o ke ʻano o ka lāʻau lapaʻau, hana mua ka hoʻoponopono hou ʻana i ka nohona o ke kanaka maʻi, ʻo ia hoʻi e pili ana i ka hōʻole ʻana o ka hana maikaʻi. ʻO ka ʻai ʻana o nā meaʻai me kahi kiʻekiʻe glycemic index (ʻo ka hiki ke hoʻonui i ke kō koko) e hoʻemi ʻia. ʻO ka regimen mālama maʻamau no ka maʻi maʻi i nā kāne, nā wahine, nā keiki a me nā ʻelemakule ua like like ia.
Hoʻohana ʻia e hōʻemi i ka nui o nā momona holoholona, nā haʻahaʻa māmā ma kāu meaʻai. Pono nā papaʻaina a ma nā ʻāpana liʻiliʻi. Pono e hana i kahi manaʻo o ke kumukūʻai o ka ikehu ma ke ao a, e pili ana i kēia, e hoʻolālā i ka haʻalulu kaloli o nā meaʻai. Me kahi nohona haʻalulu, ʻaʻole ʻoe e ʻai i kahi kīʻī o ka papaʻaī a me kahi pā anana me ka ʻiʻo, holoi ʻia me kaʻaila momona. ʻAʻole pono e haʻalele ʻia nā lāʻau lapaʻau inā ʻōlelo ʻia. Ke hōʻike nei i ka hana pilikino i ke ʻano o ka jog a iʻauʻau paha.
ʻO nā pahuhopu nui o ka maʻi
Hoʻomaka ka hoʻomaʻamaʻa ʻana i ka hoʻohana ʻana i hoʻokahi lāʻau lapaʻau a hoʻololi pono i kekahi, a laila, inā pono, i ka insulin. Hoʻolālā ʻia ka ʻike paʻakikī o ka maʻi maʻamau ʻo 2 ke kī i nā maʻi mai kekahi mau kuhikuhi:
- Pono ka Therapy e hoʻoikaika i ka hana o ka insulin, e alakaʻi ana i ka uku no ka maʻi diabetes.
- Pono e hoʻokō i ka hōʻemi o ka pae o ka pale ʻana o ka insulin i nā kino o nā kino.
- E hoʻolohi i ka luhi o ka glucose a me kona komo ʻana mai ka gastrointestinal tract i loko o ke koko.
- E lawe i ka pae ʻana o nā lipids ma ke koko (dyslipidemia).
Hoʻolālā no ka maʻi type 2 me ka ʻole o ka lāʻau lapaʻau
He mea pono i nā ʻoihana kūʻai lāʻau e kākoʻo i ka kuhi e pono nā maʻi kolohe e lawe i nā inikini insulin a lawe i nā lāʻau lapaʻau-normalizing i ko lākou ola āpau. Akā ʻo insulin a me "chemotherapy" i loaʻa i kā lākou hopena ʻaoʻao. No laila, pili pono ka mālama ʻana i nā lāʻau lapaʻau. Nui nā ʻike o nā lāʻau lapaʻau-manuʻa:
- Ke hoʻohuli nei i kaʻai kai haʻahaʻa-kiʻekiʻe a hoʻonui i ka pinepine o nā meaʻai.
- Nā lāʻau lapaʻau lāʻau lapaʻau, e kuhikuhi ana i ka lawe ʻana i nā mea kanu a me nā aʻa i ka nui o ka pae i ka ʻai, e hoʻemi ana i nā pae o ke kō.
- Acupuncture Mālama i ka hana ʻana o ka insulin, hoʻomaikaʻi i nā helu koko.
- E kōkua ka hoʻomaʻemaʻe ʻana i ka wela o ka glucose.
Physiotherapy
ʻO ke hoʻohana ʻana i nā ʻano kino like ʻole (ka māmā, ka radiation, ka wela a me nā mea ʻē aʻe) ua hōʻoia i ka hopena olakino. Hoʻohana ʻia nā kākia ʻana:
- Nā ʻrpiha hao Ma ke kino, ua hoʻokomo ʻia nā lāʻau lapaʻau i loko o ke kino e loaʻa ai ka hopena therapeutic ma ke kino. Hoʻomaopopo ʻia nā maʻi hakahaka i nā electrophoresis me ka magnesium.
- ʻĀnikopa. Me ke kōkua o nā pono hana kūikawā, ua hoʻopili ʻia kekahi kihi hiʻona i ka pancreas.
- Hoʻolālā. ʻO ke ʻano ke hoʻoilo i ka oxygen i loko o ke keʻena kūikawā. Hoʻohana pono no ka hypoxia ma nā maʻi diabetes.
- Plasmapheresis He koko hoʻomaʻemaʻe ia. Hoʻomaʻamaʻa ʻia no nā maʻi hānai me ka loaʻa ʻole o ka hana ʻole, ʻalo a septic.
- ʻO ka mea maʻi Ozone I ka wā o ka hana maʻi, hiki i ka hāmeʻe o nā cell i ka glucose, e hoʻemi ana i ke kōpaʻa koko.
Hoʻomaʻamaʻa kūlohelohe
Hāʻawi ke kino pilikino iā ʻoe e puhi i ka glucose nui i loko o ke koko, e hoʻemi i ke kaumaha o ke kino, e hoʻonui i ka kahe o ke koko i nā ʻuhane. Ma ka maʻi diabetes, hiki i ke kauka ke ʻōlelo i nā hoʻomaʻamaʻa:
- E hele ana ma kahi o: hoʻokiʻekiʻe i kou mau kuli, e hele ana i kahi o nā minuke 2-4.
- Kūlana: kū pololei, kau lima i lalo. A laila e hoʻi hope i kou wāwae hema, ʻoiai e hāpai ana i kou mau lima a me ke kihi ʻana i ka manawa like. A laila e hoʻoikaika, hoʻohaʻahaʻa i kou mau lima, e kū i kahi kūpaʻa.
- Inclection: kū pololei, huli i ka pā ʻana i kou manamana wāwae.
ʻO nā hopena palekana
Ua ʻike ʻia ka maʻi maʻi maʻi mai ka wā kahiko a ua hoʻomohala ʻia ka lāʻau lapaʻau i nā ala he nui a me nā hōʻailona no ka pale ʻana i ka maʻi. Hoʻolaha ka lau no nā maʻi maʻi type 2:
- Nettle: ninini i nā lau i hou ʻia me ka wai e hoʻolapalapa ai a waiho i nā hola 8, kānana a hoʻopau i ke kīʻaha hapaha, ʻekolu mau manawa i ka lā ma mua o ka papaʻaina.
- Horsetail: e hōʻiliʻili i nā ʻōpala, e ninini i ka wai a hoʻolapalapa no 5 mau minuke. E hoʻomau i nā hola ʻelua. Lawe i ka hapalua aniani i ʻelua mau lā ma mua o ka papaʻaina.
- Kūpule Dandelion: ʻahu i ʻelua mau aʻa o nā aʻa maloʻo me ka 0,5 lita o ka wai aniani a waiho no 4 mau hola. E lawe i ka hapalua o ke aniani ma mua o ka papaʻaina, ʻelua i ka lā. Pono e mālama ʻia ke ʻano o ke ʻano maʻi diabetes mellitus me nā kānaka kuʻekuʻe ma hope o ka nīnau ʻana i kahi kauka.
Hoʻolālā ʻana i ka maʻi mellitus type 2 me nā lāʻau lapaʻau
E kōkua ke kauka e ʻike iā ʻoe e ʻike i nā lāʻau lapaʻau e hoʻohaʻahaʻa i nā lāʻau lapaʻau type 2 e pili ana i ka paʻakikī o ka maʻi a me ka loaʻa ʻana o nā hoʻopiʻi i ka mea maʻi. ʻO nā hui lāʻau kaulana:
- Hoʻomākaukau Sulfonylurea - Glimepiride, Chlorpropamide. Ke hoʻoikaika nei lākou i ka hoʻōla ʻana o ka hormone pancreatic, e hōʻemi ana i ka pale ʻana i nā kinipōpeka peripheral i insulin.
- ʻO Biguanides - Metformin, hoʻonui i ka hoʻowalewale o ka akepū a me nā ʻōpū i ka insulin, e alakaʻi ana i ka hoʻolilo momona, hoʻomaikaʻi i ka momona momona.
- Nā hua waiwai o thiazolidinedione - Troglitazone, Rosiglitazone. Hoʻonui lākou i ka hana o nā mea nānā i ka insulin, e hoʻohaʻahaʻa i nā pae glucose.
- ʻO nā inhibitors o Alpha-glucosidase - Acarbose, Miglitol, hoʻonāukiuki i ka hoʻopili ʻana o nā powa i ka gastrointestinal tract, e hōʻemi ana i ka hyperglycemia.
- Hoʻopau i nā mea mālama peptidase dipeptidyl - ʻo Sitagliptin, e hoʻoulu ai i ka ulu ʻana o nā ʻāpana pancreatic.
ʻO ka lāʻau hypoglycemic waha he vipidia, e hoʻomaikaʻi i ka plasma metabolic control o glycemia. Hiki ke hoʻohana ʻia ka lāʻau lapaʻau ma ka monotherapy a i nā ʻano ʻē aʻe, me ka insulin. ʻO nā hoʻohālikelike no ka hoʻohana ʻana o Vipidia ka hele ʻana o ka hypersensitivity i alogliptin, ketoacidosis, ate a me nā maʻi o ka ʻōpū, hapai, a me ka olakino maikaʻi. ʻO ka pākīkī o ka hopena o ka lāʻau he 25 mg i hoʻokahi manawa i ka lā, me ke ʻano o ka komo ʻana o ka meaʻai.
Hoʻohanaʻia nā hana hoʻohui biologically (BAA) i ka hoʻohana ʻia ʻana o ka maʻi maʻi type 2 me ka hoʻomaʻamaʻa kūlohelohe ʻo Diapil. Ua hoʻohālikelike ʻia e hōʻemi i ke kōhi koko, e hoʻomaʻamaʻa i ka hana o ka ʻai o ka ʻaila a pale i ke kūkulu ʻana o nā hopena o ka maʻi maʻi. Ka pūnaehana o ka papa ʻaina kumuwaiwai kahi hapa o ka lāʻau andrographis, he ʻano anti-inflammatory a me tonic. Wahi a nā loiloi o nā mea maʻi e lawe nei iā Diapil, ke hōʻemi nei ka lāʻau lapaʻau i ka pono o ka insulin.
ʻO ka hopena e pili ana i ka maʻi diabetes type 2
Hoʻomaopopo ka lāʻau lapaʻau no ka maʻi maʻamau ʻo 2 me nā lāʻau lapaʻau e hiki mai ana e pili ana i ka metformin:
- ʻO ka hopena Glucophage - kahi lāʻau lapaʻau mua o ka hana lōʻihi, lawe ʻia i ka pō, pololei ma hope o 10 mau hola. ʻO ka hopena o ka intake ka haʻahaʻa haʻahaʻa ma ka ʻōpū ʻole i ke kakahiaka.
- Siofor - kahi waiwai hoʻohālikelike o Glucofage, hiki ke hoʻohana i ka pale ʻana i ka hoʻomohala ʻana i ka maʻi type 2. E lawe i nā metformin 1-2 mau papalua i ka lā. Loaʻa ka lāʻau lapaʻau i ka hapalua hola. Ke lawe ʻia nei ka hoʻonui ʻana i ka nui o ka hopena a ʻaʻole e hoʻomohala ka acidosis.
Kuhi hou me ka maʻi Diabetes 2
I kēia manawa, ua hoʻomohala ʻia e nā ʻepekema a me nā kauka ke ʻike i kahi ala hou no ka mālama ʻana i ka maʻi type 2.
- ʻO ka hoʻolaʻa haʻahaʻa-kalapona i hui pū ʻia me ka hana pilikino e hana pinepine ʻoi aku ma mua o nā pōpoki.
- ʻO nā hui o nā lāʻau lapaʻau e hoʻoneʻe i ke kō nui ma ka lolo.
- Kuiā ʻia e nā cell stem i loaʻa mai i ke kaula umbilical o nā pēpē hou.
No ka mālama ʻana i ke kō koko, pono ʻoe e hahai i kekahi kīnā. Ua hoʻokumu ʻia ia i ka helu ʻana o ka glycemic index (GI). ʻAi ʻia nā meaʻai me ka haʻahaʻa haʻahaʻa o nā lelepona i ka meaʻai me nā ʻāpana ʻole o nā pale ʻole, ke kī nui loa - ke pāpā ʻia ʻole nei. Papa inoa o nā meaʻai i ʻae ʻia a ʻae ʻia:
Kahakila, kālai, kākoti, nā ʻano āpau, nā kukama, nā ʻōmaʻomaʻo, nā ʻaka
ʻO ka palaoa palaoa, beets, ʻuala, paukena
ʻApeloti, grapefruit, plums, apple,
Melon, Nāʻaina, Pineapples
ʻĀmole, pīpī, līkī, palaoa, bulgur, oatmeal, buckwheat
Semolina, granola, cereals koke ʻole
Fractose, ʻokaʻeleʻele,
Palaka, miki waiū, pahu, nāʻaina, waffles
ʻO nā meaʻuwelu, ʻaina laiki, berena, spaghetti kūlohelohe
ʻO ka pīpī, kaʻaila, pasta, nā kuki, ka berena bula, ka palaoa palaoa, ka dumplings, nā mea pono, nā mea ʻala
Kāhi, skim milk, mauʻu holoholona
ʻO ka momona momona, nā kīwī, ka iʻa paʻakai ʻia, iʻa ʻia i ka mea ʻai
Nā waiʻala kālaiʻawa, ka pia, ka waina, kvass
Loaʻa nā huaʻai no ka diabetics
Ke komo ka meaʻai me nā kalaiʻa māmā i ke kino, loli koke lākou i loko o ke kō. Me ka diabetes, e hoʻoneʻe ʻia ka glucose, kahi maikaʻi i hoʻopili ʻia, e alakaʻi ana i kahi pōʻino o ka pancreas. Inā hoʻohana ʻia nā hāmeʻa paʻakikī (fibre, starch, pectins), a laila lohi ka absorption, ʻaʻohe kaʻaha i ka glucose, noho lōʻihi ke kanaka holoʻokoʻa.
Pono ka momona o ka meaʻai i ka papa o ka mea maʻi maʻi maʻi no ka mea e hoʻohaʻahaʻa i nā nui o ka glucose koko. I ka wā e ʻai ai, pono ʻoe e hoʻokaumaha i ke kānāwai o 25-40 g o ka fiber i kēlā me kēia lā, pono e hoʻolōʻihi ka intake i hiki i ke kino ke hoʻomaʻamaʻa i ka ʻai a ʻaʻole hoʻouka i nā ʻeha. ʻO ka hoʻohaʻahaʻa i nā haʻalulu haʻahaʻa, hoʻohiolo i ka hoʻoneʻe ʻana o ke kō, a lawelawe i ka prophylaxis o nā maʻi vascular. ʻO ka ʻano insoluble i kahi kīlā kaloli, a hōʻemi ke koko, a me ka ʻike homocysteine.
ʻO nā kāpena wai no ka maʻi diabetes
ʻO ka papaʻai o ka mea maʻi me ka maʻi type type 2 e pono e hoʻopili i nā kōpoki, no ka mea e loaʻa ke kino i ka ikehu mai o lākou, akā he mea nui e hoʻomanaʻo ka ʻokoʻa nā mea ʻokoʻa. ʻO ka mea hoʻohana nui no ka maʻi maʻi i manaʻo ʻia he paʻakikī - kahe, ke kāwili i ka meaʻai, a me ka hoʻopōʻino - maʻalahi, e hana koke ana i ka "huki" i ka glucose. ʻO nā mea maʻi me ka maʻi maʻi maʻi e pono pono i kahi meaʻaiʻai haʻahaʻa, ʻaʻole ia e hoʻonui ai i ke kō, e hōʻemi ana i ka hopena o ka hypoglycemia koʻikoʻi.
Kāohi
I mea e pale ai i ka ʻano ʻelua o ka maʻi i ka hoʻomaka ʻana i loko o ka lolo ole e hilinaʻi ʻia mai i ka insulin, a i ʻole e pale i ka holo ʻana o ka maʻi holoʻokoʻa, ke hoʻohana ʻia nā hana pale e hiki mai ana:
- e hoʻoponopono i ka hoʻoponopono ʻana i nā meaʻai,
- pipiʻi i ka ʻai haʻahaʻa haʻahaʻa, inu i nā huaora,
- hoʻoikaika kino
- hoʻopiʻi ʻia i kēlā me kēia makahiki me kahi predisposition i ka maʻi,
- oki i ka ulaula, inu i ka waiona,
- mālama i ka kaupaona maʻamau, pale i ka momona.
Hōʻalo i nā puʻupuʻu insulin
Ua hoʻomaka ʻo Thiazolidinediones e hoʻohana i nā mea hoʻohana i hoʻohaʻahaʻa i ka hyperglycemia, ʻoi aku nei hou. ʻAʻole hopena kēia mau lāʻau lapaʻau i nā pū me nā beta; ma ka mea ʻē aʻe, hoʻomaikaʻi lākou i ka ʻike ʻana o nā ʻiʻo peripheral i insulin. A ʻo kahi hopena, hoʻemi ʻia ka thiazolidinediones i ka glucose a he hopena maikaʻi hoʻi i ka lehelehe lipid.
Ma keʻano holoʻokoʻa, hiki i nā lāʻau lapaʻau o kēia pūʻulu ke hōʻemi i ka hoʻoliʻiliʻi o ka puna ma o 0.5-2%, no laila lawe pinepine lākou i ka hui me nā metformin, injections insulin a me derivatives sulfonylurea. ʻO nā hiʻohiʻona o nā lāʻau lapaʻau i nā papa i pili i ka papa o ka thiazolidinediones ʻo Pioglar, Actos a me Diaglitazone. ʻO ka ʻaoʻao kūpono o kā lākou hoʻohana ʻana me ka haʻahaʻa haʻahaʻa o ka wikiwiki o ka hoʻolohiʻana i nā pae kō. Kēia mau lāʻau lapaʻau like ʻia ka mea i hoʻohiki loa ʻia no ka hoʻopau ʻana i ka pale ʻana i ka insulin.
Hōʻike ʻia ʻo Biguanides e ka mea hoʻokahi wale nō ka manaʻo - metformin, kahi ʻāpana o nā lāʻau lapaʻau o kēia hui. Hoʻomaka ka hana lapaʻau e hoʻohana i nā mea ma hope o 1994. Ma ka 2017, he mau biguanides ka mea i lilo i mea kaulana loa ma ka mālama ʻana i ka maʻi maʻi type 2. Hoʻopau ke kime i ka hana o ke kime o ka hana o ka glucose e ka ʻāʻī a me ke komo i loko o ke koko. Eia kekahi, e hoʻonui i ka hoʻololiʻana i nā kinipili peripheral i insulin. Hāʻawi ka mākeke pharmacological o Lūkini i kahi nui o nā papa no ka maʻi diabetes type 2 i loaʻa ke ʻano hana. - metformin hydrochloride. ʻO nā analogues e like me Metformin, Siofor, Glucofage a me nā mea ʻē aʻe.
ʻAʻole e hoʻomaopopo ʻia ma waena o nā hiʻohiʻona kūpono o ka hoʻohana pono ʻana i kēia mau lāʻau, aia kahi haʻahaʻa o ke kūlana hypoglycemic state, ka pale ʻana i ka atherosclerosis, ka hoʻolilo nui ʻana a me ka hiki ke lawe pū me ka hoʻomehana insulin a me nā lāʻau lapaʻau e hoʻokaʻawale aʻe.
I waena o nā hiʻohiʻona maikaʻi loa o ka hoʻohana ʻana i ka metformin, ʻekolu mau mea e hiki ke hōʻike.
- ʻO ka hanu Digestive ma ka hoʻomaka ʻana o ka hana e pili ai i ka hoʻohui o ke kino i ka hana o ke kinona. ʻO nā maʻi maʻamau ka maʻi a me ka luaʻi, ke nānā ʻana, ka nele o ka momona, ka lemaki.
- ʻO ka hopena o ka acidosis lactic.
- Hoʻopilikia ka lōʻihi o ka mālamaʻana i ka hoʻoliʻi o ka vitamin B 12 i loko o ke kino.
ʻAʻole hiki iā ia ke hoʻohana i nā papa metformin no nā ala o ke ake, ka pēpē o ka ʻōpū, ka papahuli a i ʻole ka puʻuwai naʻau.
ʻO nā lāʻau hou loa
Mai ka makahiki 2006, ma ka hana lapaʻau, hoʻomaka lākou e hoʻohana i nā lāʻau hou i kapa ʻia ʻo "DPP-4 inhibitors." ʻAʻole lākou e pili ana i ka hana ʻana o ka insulin e nā beta beta.Kuhi lākou hana i ka pale ʻana i ka polypeptide o ka like o ka glucan-like o ka ʻano mua (GLP-1), ka hana o ka mea i loko o ka ʻōpū, mai ka hopena i ka hopena o ka enzyma DPP-4. ʻO ka inoa o nā lāʻau lapaʻau mai kēia pūʻulu mai ka inoa o ka ʻaʻoma.
Hoʻonui ka GLP-1 i ka pancreas, ma muli o ke hoʻomaka ʻana e hana ʻia ka insulin i ka nui. Hoʻopilikia ka GLP-1 i ka hiki ʻana o ka holomua o ka glucagon, ka mea e hoʻopilikia kino i ka hoʻemi ʻana i ke kō.
ʻO nā pono o ka hoʻohanaʻana i ka DPP-4 inhibitors ʻo:
- ʻO ka hiki ʻana o ka hypoglycemia ma ke ʻano o ka lāʻau lapaʻau e hoʻopau i kāna hana ma hope o ka hoʻohālikelike i nā pae glucose.
- Hoʻololi ʻia ka hopena o ka hoʻonui ʻana i ke kaupaona kino ma muli o ka lawe ʻana i nā paila.
- Hiki iā lākou ke hana i kahi paʻakikī me ka aneane āpau, ma ka hoʻohui i nā agonist o nā mea hoʻokipa GLP-1 a me insulin.
Ma waena o nā hopena maikaʻi ʻole, hiki iā ʻoe ke hoʻokaumaha i ka digestive huhū, kahi mea i hōʻike pinepine ʻia e ka ʻeha o ka ʻōpū a me ka ʻōpū. ʻAʻole ʻōlelo ʻia kēlā mau penikala maʻi maʻi no ka hoʻohana ʻana i ka palaki ʻana o ka palupalu a i ʻole nā palaka. Ua māhelehele ʻia kēia hui lāʻau lapaʻau i: saxagliptin (Onglisa), vildagliptin (Galvus), sitagliptin (Onglisa).
ʻO agonist reseptor GLP-1 he mau hormones nā mea e hoʻoulu i ka hana insulin pancreatic a hoʻoponopono hou i nā ʻenemi liuliu nāwaliwali. Eia kekahi, ʻo kēia ʻano o ka lāʻau e hōʻemi ma luna o ka momona i ka poʻe maʻi lapaʻau. ʻAʻole hana ʻia kēia mau lāʻau i ke ʻano o nā papa, hiki ke kūʻai ʻia ia ma nā ʻano o nā ampoules no ka inikua. ʻO ka mea i hōʻike ʻia o ka hui, ʻo ka Viktoza hou, a ʻo Baeta hoʻi.
Mālama ka paleʻana o ka Alpha glucosidase i ka hoʻololi ʻana o ka maʻi glucose mai nā huapalapala. Hoʻohana ʻia nā lāʻau o kēia pūʻulu i ka manawa e loaʻa ai ka mea maʻi i ka neʻe o ka glucose ma hope o ka ʻai ʻana. Hiki ke hoʻohui pū ʻia kēia mau kālā me nā lāʻau lapaʻau e hoʻemi ana i ke kō. ʻO kahi mea liʻiliʻi o nā inhibitors o alpha-glucosidase ka mea ua pāpā ʻia kā lākou hoʻohana ʻana i nā pathologies bitinal.
ʻO nā hopena ʻino maikaʻi loa ma hope o ka lawe ʻana i nā lāʻau lapaʻau ka pilikia o ka hoʻowalewale - ʻo ka hoʻonui ʻana o ka hoʻomohala ʻana i ka wahie i loko o ka ʻawa a me ka huehue. Me ka metformin, ʻoi aku ka maikaʻi o kēia lāʻau lapaʻau inā ʻaʻole hoʻohana, no ka mea e pili pū ana i ka ʻōnaehana o ke kanaka. ʻO nā ʻelele o kēia hui he Diastabol a me Glucobay.
He mea hoʻonāukiuki i ka hoʻonele
Ua ʻike ka lolo e pili ana i nā derivatives sulfonylurea no ka manawa lōʻihi, akā hoʻohana wale ia i ka mālama ʻana o nā maʻi maʻi maʻi. ʻO kā lākou hopena hypoglycemic i ʻike pinepine ʻia i ka wā o ke Kaua Honua II.
Hoʻopilikia kēia lāʻau lapaʻau i ka hana ʻana o nā poli beta i loaʻa i ka pancreas, ka mea e kāpae i ka hormone. Hoʻomau hou nā kumulepala Sulfonylurea i ka hana o ka insulin a hoʻonui i ka ʻike ʻana o nā ʻenehana cell i ka insulin.
Eia naʻe, eia kēia mau kālā kālā i nā hopena like ʻole e like me:
- moku'āina hypoglycemia
- ka hele ʻana o cell beta
- loaʻa ka paona.
ʻO ka overstrain mau loa o ka pancreas e alakaʻi i ka mea ʻo ke ʻano lua o nā papa hana i ka mea mua. Hoʻomaopopo kēia, i mea e mālama pono ai i nā waiwai o ka glucose i loko o nā palena maʻamau, pono ka mea maʻi e kau pinepine iā ia i ka hormone. Hoʻokaʻawale ʻia nā hua lepo o ka sulfonylureas i kekahi mau papa:
- Glyclazide - ʻ MVlelo Diabeton MV a me Glidiab MV.
- ʻO Glimepiride - ʻO Glemaz lāuaʻo Amaril.
- Glycvidon - Kūkulu.
- Glibenclamide (Maninyl).
ʻO nā lāʻau lapaʻau o ka pūʻulu meglitinide hōʻeuʻeu hoʻi i ka hana ʻana o kahi kōhune hoʻohiolo puna. Ua hōʻike ʻia lākou no kēlā poʻe maʻi pāʻai i ka mea e hoʻonui ai ka hoʻoliʻu o ke koko ma hope o ka ʻai ʻana. Hōʻālua kēia pūʻulu i nā papa ʻelua o ka lāʻau lapaʻau - nateglinide (Starlix) a me ka repaglinide (Novonorm).
Hiki ke noʻonoʻo ʻia ka maikaʻi o ka hoʻohana ʻana i kēia mau lāʻau inā ʻaʻole lākou e hoʻopilikia i ke kaumaha o ke kino a ke kanaka maʻi ʻaʻole i alakaʻi i kahi kūlana o ka hypoglycemia.
Eia naʻe, nā lāʻau lapaʻau ma kēia pūʻulu e hoʻokau kekahi o nā hopena maikaʻiʻole e pili ana i ka hana a me ka paluhi, a me ka maʻi o ka ʻōpū o ka ʻaoʻao o ka hanu.
ʻO ka hemahema o ka lāʻau lapaʻau he kumukūʻai nui loa, ʻaʻole hopena koʻikoʻi hypoglycemic hopena a hoʻohana hou i ka wā o ke ao.
Therapy a me nā hopena o kona hōʻole
ʻO nā hōʻailona nui o ka maʻi hānai mau ke hele pinepine i ka hoʻomaha hoʻomaha a me ka makewai mau. Kēia mau ʻōmaʻomaʻo ʻano ʻelua e hōʻike i kahi hihia o ka pae o ka glycemia. Inā ʻike kekahi i kēlā mau ʻōuli i loko ona, pono ia e ʻike i kahi lāʻau lapaʻau i ka wā e hiki mai ana.
ʻO ke kumu no ka make kiʻekiʻe o nā maʻi me nā maʻi mellitus e pili pono ana i ka mālama ʻana ʻole a me ka loaʻa ʻole. Ma ka manawa i koho ʻia ai me ka loea lapaʻau, pono e haʻi ka mea maʻi i nā maʻi āpau e hopohopo nei iā ia. Ma hope o ke kamaʻilio ʻana, kuhikuhi ke kauka i kahi maʻi maʻi o ka maʻi maʻi.
Nui nā hoʻokolohua e hiki ai ke aʻo e ʻike i ke kiʻekiʻe o ke kō, akā maʻalahi, a ʻoi loa ka wikiwiki o ka nānā ʻana i ke koko mai ka manamana lima a mai kahi vein paha. Inā kiʻekiʻe nā hopena ma mua o 5.5 mmol / L (nā wai o ka capillary) a me 6.1 mmol / L (koko venous), hiki i kēia ke kuhikuhi i ka prediabetes a i ʻole diabetes. I mea e hoʻoholo ai i ke ʻano o ka maʻi, lawe ʻia kahi ʻano noiʻi no ka C-peptides a me nā ʻike o nā antibodies GAD.
Inā ua hōʻaʻi ke kauka i ke ʻano maʻi type 2, e hoʻomohala ana ia i kahi lāʻau lapaʻau kūikawā e loaʻa ana i ʻehā mau māhele:
- glycemic control maʻamau,
- mea ʻai kūikawā
- e hoʻoneʻe kino
- lawe i nā lāʻau lapaʻau.
ʻO ka mālama wale i kēia mau lula a hiki iā ʻoe ke kāohi i ka nui o ke kō i loko o ke koko a pale i ka hoʻomohala ʻana o nā hopena koʻikoʻi o ka maʻi maʻi. ʻO kahi ʻano luhi i kou olakino e hiki i ke alakaʻi i ka:
- ʻO ka huehaleha hopena.
- Retinopathy Diabetic - ʻike maka ʻia ka hopena ma muli o ka hana a ka retinal.
- ʻO ka neuropathy Diabetic ka maʻi kahi o ka pīpī.
- ʻO Gangrene o nā palena haʻahaʻa. I kēia hihia, pono paha ke kuʻekuʻe wāwae e pono ai no ka maʻi maʻi maʻi.
- ʻO kahi comly glycemic.
- ʻO kahi kīʻaha mikina Myocardial a i ʻole hahau.
Pono ʻoe e mālama i ka maʻi diabetes i ka manawa. ʻAʻole kēia maʻi, he kenekulia hope loa, mahalo i ka ʻenehana hou, ke noho nei nā kānaka me ia piha.
ʻO ka mea nui, ʻaʻole hāʻawi e haʻalele. Ke kū nei ka lāʻau lapaʻau hou: i kēlā me kēia lā, hoʻomohala ʻia nā ʻepekema i kahi lāʻau hou e loaʻa ana nā contraindications liʻiliʻi a loaʻa kahi hopena therapeutic maikaʻi loa.
Pono e hoʻomanaʻo ʻia i ka wā e hoʻohana ai i ka lāʻau lapaʻau, pono ʻoe e pili i nā ʻano kūpono a me nā ʻōlelo a ke kauka. Ma kēia ala, hiki ke mālama ʻia nā pae glucose i nā pae maʻamau. ʻO ke wikiō ma kēia ʻatikala e kamaʻilio nei i ka mālama ʻana no ka maʻi diabetes type 2.