Vipidia, nā Lūkiniʻāina Lūkini me nā kumukūʻai a me nā loiloi

Vipidia (nā papa) Rating: 183

Mea Hana: No ka huahua
Kuhi puka:

• ʻLelo. 12.5 mg, 28 pcs., Kumukūʻai mai 973 mau rubles
• ʻLelo. 25 mg, 28 pcs., Kumukūʻai mai 1282 mau rubles

ʻO nā kumukūʻai Vipidia ma nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Vipidia he māpana hypoglycemic i nā papa me alogliptin. Hāʻawi i kahi hōʻemi i ka hemoglobin glycosylated a me ka glucose. Ua hōʻike ʻia ma ka hihia o ka maʻi mellitus type 2 i ke ʻano o ka monotherapy, a me ka hoʻohui pū ʻana me nā mea hana hypoglycemic ʻē aʻe. ʻO ka maʻa loa ka 25 mg / lā, lawe ʻia ma kahi o ka meaʻai. Contraindicated ma ka maʻi ketoacidosis maʻi, type 1 diabetes mellitus, hōʻeha nui o ka naʻau puʻuwai, nā māla a me ka puʻuwai. ʻO nā hopena ʻaoʻao ka hilahila o ka hōʻeha, ka ʻeha i ka epigastrium, nā wikiwiki, nā maʻi lēʻeha o nā kino ENT. ʻAʻole maona ʻia nā keiki ma lalo o 18 mau makahiki a me nā wāhine hāpai wahine ma muli o ka nele o ka ʻike ma ka noi.

Nā hiʻohiʻona o ka lāʻau Vipidia

ʻOi like ka analogue mai ka 863 mau rubles.

Mea Hana: Merck Sante SAA.S. (Palani)
Kuhi puka:

• Nā papa 500 mg, 30 pcs., Kumukūʻai mai 110 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai Glucophage i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO ka lāʻau Farani no ka mālamaʻana i nā maʻi maʻi 2. Kuhi i nā papa i loaʻa mai 500 a 1000 mg o ka metformin ka mea hana hoʻokahi. Aia kekahi mau contraindications, no laila, ma mua o ka lawe ʻana i Glucofage, pono e kūkā me kahi loea.

ʻOi like ka analogi mai ka 182 mau rubles.

Mea Hana: Novartis (Switzerland)
Kuhi puka:

• Nā Papa 50 mg, 28 pcs., Kumukūʻai mai 791 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai Galvus i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Galvus kahi papa papa no ka mālama ʻana i ka maʻi mellitus type 2 e pili ana i ka vildagliptin i loko o kahi waihona o 50 mg. Hiki ke hoʻohālikelike ʻia e like me monotherapy a ma ke ʻano o ka hui hoʻohui ʻana i ka hihia o ka maikaʻi o ka meaʻai a me ka hana.

ʻOi like ka analogi mai ka 795 mau rubles.

Mea Hana: Hemofarm A.D. (Serbia)
Kuhi puka:

• ʻLelo. 500 mg, 60 pcs., Kumukūʻai mai 178 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai Metformin i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO ka Metformin kahi lāʻau lapaʻau hypoglycemic Serbian no ka hoʻohana kūloko. ʻO ka hoʻonohonohoʻana o nā papa i loko o ka waihona hana ikaika o ka inoa like i loko o kahi waihona o 500 a 850 mg paha. Ua kuhikuhi ʻia no ka mālama ʻana i ka maʻi maʻamau ʻo 2 (i nā pākeke), ʻo ia hoʻi i nā maʻi me ka hiʻona.

Ua ʻoi aku ka mea kūʻai ma ka analogue mai 799 mau rubles.

Mea Hana: Ioana Maoli (USA)
Kuhi puka:

• Nā papa ʻaina 5 mg, 30 pcs., Kumukūʻai mai 1772 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai no Onglisa i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Onglisa kahi lāʻau lapaʻau ʻAmelika no ka mālamaʻana i ka maʻi mellitus type 2 e pili ana i ka saxagliptin i loko o kahi maʻi o 2.5 a i ʻole 5 mg. Ua hoʻohālikelike ʻia i ka hoʻohui ʻana o ke kino a me ka meaʻai e hoʻomaikaʻi ai i ka mana glycemic.

Ua ʻoi aku ka uku o ka analogue mai ka 1236 mau rubles.

Mea Hana: Merck Sharp a me Dome (USA)
Kuhi puka:

• Nā Papa 100 mg, 28 pcs., Kumukūʻai mai 2209 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai no Januvia i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Lāvia kekahi lāʻau lapaʻau ʻAmelika no ka maʻi maʻi. ʻO ka papa hana: sitagliptin (ma ke ʻano o ka phosphate monohydrate) 100 mg. Hiki ke hoʻohana i ka hoʻohui i ka hana kino a me ka meaʻai e mālama i ke kō koko.

Ua ʻoi aku ka uku o ka analogue mai ka 675 rubles.

Mea Hana: Beringer Ingelheim (Austria)
Kuhi puka:

• Nā papa ʻaina 5 mg, 30 pcs., Kumukūʻai mai 1648 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai no Trazhenta i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Trazhenta - kahi lāʻau lapaʻau Austrian i manaʻo ʻia no ka mālama ʻana i ka maʻi mellitus type 2, hiki ke kuhikuhi ʻia e like me ka mono- a ma ke ʻano o ka hui pū ʻana. ʻO ka mea hana kūpono i ka hoʻopili hui ʻo linagliptin i loko o kahi waihona o 5 mg. ʻAʻole i kuhikuhi ʻia ka Trazenta no ka maʻi type 1, i ka wā hāpai, lactation, me nā keiki ma lalo o ka 18 mau makahiki o ka makahiki.

Vipidia: nā kuhikuhi no ka hoʻohana ʻana, ke kumukūʻai, nā loiloi a me nā analog

ʻO Vipidia ka lāʻau lapaʻau e hoʻohana ʻia e like me nā kuhikuhi i hoʻohana ʻia i ka maʻi diabetes. ʻO nā maʻi me kēia maʻi ʻana e hoʻomau mau i ka glucose koko me ka hoʻohana ʻana i kahi meaʻai paʻa, a inā ʻaʻole lawa, a laila lapaʻau ʻia.

E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana a me ka pōpoki

Ke hana ʻia nei ka lāʻau lapaʻau i ke ʻano o nā papa oval i uhi ʻia me kahi membrane film. Nā pāʻālua:

• 12.5 mg - nā papa melemele
• 25 mg - kahi mālamalama ʻulaʻula.

Hoʻohana ʻia ka huahana ma ka paila pepa. Ke kīʻaha: 4 papaha, loaʻa iā 7 papa, he 28 mau ʻāpana i kahi pā.

ʻO ka waiwai ikaika o ka lāʻau alogliptin. Nā mea kōkua

• konekena stearate,
• sodium polio
• mikuleka
• Hoʻopiʻi

ʻO ka uhi ʻia o ke kiʻi paʻi o ka papa ma:

• hohaihono,
• hoʻoneʻe hao hāhi
• titanium hone
• macrogol
• aniani F1 hina

Nā hana lāʻau lapaʻau

ʻO Alogliptin he meleptidyl peptidase-4 pipili paʻa kahi koho. ʻO DPP-4 ka enzyme nui e kumu ai i ka wikiwiki o ka hoʻololi ʻana i nā hormone o ka ʻohana incretin.

Ma keʻano kūikawā, he glucose-dependotine insulin -ropypypide (HIP) a me nā puhikena e like me peptide-1 (GLP-1). Hana ʻia kēia mau hormones i loko o nā ʻāpana, a ʻano like ko lākou pae ma ka ʻai i ka ʻai.

Hoʻomoʻi ka hopena o ka HIP a me GLP-1 i ka hoʻopololei ʻana i ka synthesis o ka insulin i ka pancreas.

Hoʻopili i ka peptide like Glucagon e hōʻemi i ka nui o ka glucagon a hoʻolōʻihi i ka hana o nā glucose i loko o ka ate.

Me nā loli o ka level o ka incretins ma lalo o ke kumu o alogliptin, hoʻonui i ka hana o ka insulin a hoʻemi ka glucoseagon me ka hoʻonui ʻana i ke kō.

I ka poʻe me ka maʻi diabetes, ʻo ia mau loli e alakaʻi i ka normalization o ka hemoglobin glycosylated a me nā mea hoʻokaʻina koko ʻē aʻe ma mua a ma hope o ka ʻai.

Lapaʻau lāʻau

Hoʻopilikia ka lāʻau lapaʻau i kahi kanaka olakino a me ka mea maʻi i ka maʻi diabetes. Hoʻomoʻe ʻo Alogliptin i loko o ke kino e ka aneane 100%, me ka ʻole o ka ʻai i hoʻopau ʻia. Me ka papa pākahi, hoʻokomo koke ka mea ola i ke koko, kahi ma hope o 1 a 2 mau hola ka loaʻa ʻana o ka nui o ka lāʻau.

Hāʻalo ʻia ʻo Alogliptin e hoʻopuka nui i nā kiko. ʻO ka pilina me nā protein protein e like me 20-30%.

Me ka hoʻohana mau ʻana o ka lāʻau lapaʻau, ʻo ka hōʻiliʻili o kahi mea e hana ai i ka biologically i ke kino, e like me ka ʻepekema data, ʻaʻole ʻike ʻia i nā kānaka olakino a maʻi paha.

Ma loko o 21 mau hola ma hope o ka lawe ʻana i ka lāʻau lapaʻau, ʻo 70% o nā mea e hoʻopiʻi ʻia e nā keiki ma ka hana ʻole i hoʻololi ʻia, 13% e nā iwi mai.

Ua kuhikuhi ʻia ʻo Vipidia no ka maʻi maʻamau o ka lā 2. Mālama maikaʻi ka hāmeʻa i nā mea maʻi, ʻoiai me ka pani ʻole ʻole ʻana i ka meaʻai a me ka nele o ka hana kino pono. Hiki ke hoʻohana ʻia ka lāʻau lapaʻau e like me ka monotherapy. Hiki iā ʻoe ke inu pū me ia me nā lāʻau ʻē aʻe e kōkua ai i ka hoʻēmi ʻana o ka pauku o ke kō i ka wai koko.

Nā Hoʻohui

E like me kekahi lāʻau lapaʻau, loaʻa iā Vipidia kona mau palena. Heluhelu maikaʻi iā lākou.

ʻAʻole pono ka ʻākena me ka:

• hypersensitivity o ke kino i kekahi mea i pili i ka lāʻau lapaʻau,
• maʻi diabetes type 1
• maʻi maʻamau ketoacidosis,
• nāwaliwali o ka puʻuwai
• hoopoino nui ia,
• hapai a me lactation,
• keiki malalo o 18 makahiki.

Me ka akahele:

• lōkohu
• hano papaleha maʻi,

Nā ʻōkuhi no ka hoʻohana (dosage)

Pono ʻia ʻo Vipidia i mua a maʻa. Hoʻomaopopo ʻia e hoʻohana i nā mea hou aku ma mua o 25 mg i kēlā me kēia lā. Hoʻohua ʻia i ka manawa me ka lāʻau like, e like me:

Me ka hui pū ʻana o Vipidia me ka metformin a i ʻole thiazolidinedione, ʻaʻole i loli ke ʻano. E hoʻokaʻawale i ka hopena o ka hypoglycemia, i ka wā e kauoha ʻia ai ka lāʻau lapaʻau i ka wā like me ka insulin, pono ia e hōʻemi i ka dosage o ka hopena. Inā no kekahi kumu ke poina iā ʻoe e inu i ka lāʻau lapaʻau, pono ʻoe e hoʻoponopono hou i ka hiki. Akā i ka manawa hoʻokahi ʻaʻole pono e lawe ʻia ka hopena ʻelua.

Nā hopena hopena

Aia kekahi manawa e hele mai nā hōʻailona ʻino ma muli o ka lāʻau Vipidia. Hiki i ka mea maʻi ke hoʻopiʻi i:

• lie kanikela
• ʻōpū hanu
• nasopharyngitis,
• ʻeha i loko o ka ʻōpū
• ʻeha a me ka ʻeha,
• ka hooulu ʻana o ka pancreatitis,
• ka hoʻohua ʻana o ka hana hoʻopaleha.

Inā i ʻike ʻia kēlā mau hōʻailona ʻōlule, pono e hōʻike i kāu kauka. Hiki iā ia ke hoʻoholo e hoʻomau i ka mālama ʻana me ka lāʻau lapaʻau ʻaʻole paha. Hōʻikeʻike ikaika o nā hōʻailona ma luna e pono i ka haʻalele koke ʻana i ka lāʻau lapaʻau.

Ke keu

ʻAʻole hiki i kahi ākea kūʻokoʻa ke hoʻoweliweli i ka poʻe. Pono ke kōkua o ke kauka i nā hihia wale nō inā he pale ʻole ia iā Vipidia a i ʻole ke lawe ʻana i ka lāʻau lapaʻau e nā poʻe e loaʻa ana i nā maʻi i ka papa inoa o nā contraindications. ʻO ke kōkua mua no ka overdose - gastage lavage.

Nā ʻōlelo kikoʻī

ʻO ka hoʻohana kūpono ʻana o Vipidia me ka insulin a me nā lāʻau ʻē aʻe e hoʻemi ana i ke kōpaʻa koko e koi ana i ka hoʻoponopono dosage e pale i ka hoʻomohala ʻana o ka hypoglycemia. Wahi a nā haʻawina loiloi, ʻo ka launa pū ʻana o alogliptin me nā mea olakino ʻē aʻe i hōʻike ʻole i nā loli like.

Hoʻopilikia nui ʻo Alogliptin i ke kino, no laila i ka wā mālama e pono ʻoe e hōʻole i ka inu ʻona.

ʻAʻole ia ka lāʻau "Vipidia" i ka hiamoe, no laila ke kaʻa ʻole a me nā hana ʻē aʻe e koi ai ka nui o ka nānā aku.

He mea nui: ua hōʻike ʻia nā noiʻi ʻaʻole maikaʻi loa ka lāʻau lapaʻau ma ka ʻaoʻao, kahi hana ʻokoʻa i kāna mau hana. E hiki i ka wā e hiki ai ke maʻi pancreatitis. No laila, ma mua o ka hoʻohana ʻana i ka lāʻau lapaʻau, pono ia e hoʻomaʻamaʻa piha i ka hoʻohālikelike ʻana a hoʻohālikelike i nā kamaa a me nā mea ʻē.

Ma muli o ka hapa ʻole o ka ʻike e pili ana i nā kūlana ʻino i ka wā hapai a me ka lactation, ʻoi aku ka maikaʻi e inu i ka Vipidia.

Na keiki a me ko elemakule

Ke koho nei i ka lāʻau lapaʻau i nā keiki a me nā wā ʻōpio ma lalo o 18 makahiki o ka maʻi contraindicated, ma muli o ka nele o nā hōʻike maʻi i kēia makahiki.

Hiki i nā mea maʻi ma luna o 60 mau makahiki ke inu i ka "Vipidiya". ʻAʻole pono ka hoʻoponopono ʻia maʻamau e hoʻoponopono ʻia. Eia nō naʻe, pono e hāpai i ka noʻonoʻo o ka hōʻemi o ka hōʻemi o ka hana o nā pūpū a me nā ate i hilinaʻi i ka nui o ka alogliptin.

Nā kuleana a me nā kūlana e waiho ai

E hoʻomau i ka lāʻau lapaʻau ma kahi wahiʻeleʻele, anuanu ma kahi o nā keiki. ʻO ka wā i hoʻohana ʻia he ʻekolu makahiki mai ka lā o ka hoʻopuka. Hoʻohui ʻia ka lā hana o ka hoʻopili ʻana i ka pale. Ke papa ʻia i ka lāʻau kūʻai pau.

Kūlike ke kumukūʻai o Vipidia i nā lāʻau lapaʻau e like me ka nui o ke ʻano o ka lāʻau lapaʻau a me ka māhele o ka noho ʻana. I ka awelika, ʻo 845 - 1390 mau rubles.

Hoʻohālikelike me nā kikowaena

Inā no kekahi kumu ke kūpono i ka lāʻau lapaʻau i ka mea maʻi, ke noi nei ke kauka i kahi lāʻau lapaʻau i hiki ke hoʻololi ʻia.

Ka papa inoa o nā hoʻohālikelike o ka lāʻau lapaʻau "Vipidia":

Tagu inoa	Loaʻa nā pono	Mea nā hemahema	Kūʻai
Galvus Met	ʻO kahi ala e hoʻohaʻahaʻa i nā pae haʻahaʻa. Kōkua ia i ka pau ʻana o nā kauā he nui me ka ʻole hoʻokiʻī.	ʻO kahi papa nui o nā hopena pili maikaʻi. ʻO ke kumukūʻai kiʻekiʻe o ka lāʻau.	Mai 780 mau rubles.
Alogliptin	Kōkua i ka hoʻoliʻiliʻi i nā pae glucose. ʻAʻole kumu e hoʻonui i ka metabolism. ʻAʻole e hōʻiliʻili, ʻuʻuku loa ʻia mai ke kino.	ʻAʻole hiki ke hoʻohanaʻia no nā ala o nā palaka, nā aʻalima, nā pancreas. ʻAʻole maʻalahi ka lāʻau.	Mai 845 rubles.
Januvia	Hoʻopau i nā lilo kaumaha, hoʻemi i ka makemake, hoʻomaʻamaʻa i nā ʻāpana koko.	Uku. He nui nā contraindications no ka hoʻohana ʻana, no laila he mea nui a kuhikuhi ke kauka i ka lāʻau lapaʻau.	Mai 1350 mau rubles

ʻO ka hapanui o nā pane mai nā maʻi maʻi maʻi e hopu ana iā Vipidia. Hoʻomaʻamaʻa maikaʻi kēia mau papaʻu i ka glucose koko, ke hoʻomanawanui maikaʻi ʻia, akā e hoʻohana wale ʻia e ke kauka. ʻAʻole makemake ka poʻe i ka ʻoiaʻiʻo o ke kumukūʻai o ka lāʻau i mea kūʻai. Eia kekahi mau ʻike maoli:

Ua maʻi wau i ka maʻi diabetes 5 mau makahiki i hala. Ua hoʻopaʻa ʻia ʻo ia me kahi endocrinologist, inu nui i nā lāʻau lapaʻau. Akā i kekahi mau pule ma hope iho, ua hoʻomaka ke kō i ke kō i ka 18 mau pūʻulu. Ua kuhikuhi mai ke kauka iaʻu i kahi Vipidia. Lawe wale wau i hoʻokahi papa pākahi i kēlā me kēia lā, maʻamau ke kō. Ua hauʻoli loa wau. Loaʻa iaʻu iho i loko o kēia lāʻau lapaʻau hoʻokahi pono wale nō.

Hoʻololi maikaʻi ʻo Vipidia i ka insulin. A i nā hoʻohālikelike me kēia, pono ke lawe ʻia i ka lā hoʻokahi i ka lā hoʻokahi. ʻAʻole pono ke mālama i kahi kīʻai. ʻO kaʻu maʻiʻai, nā papaʻu i hoʻokaʻawale i ke kiʻekiʻe o ka glucose i ke koko, no laila ua hōʻole wau i ka insulin no ka lōʻihi. Kahuikau ka ʻoiaʻiʻo i ke kumukūʻai, ʻaʻole maʻalahi ka lāʻau, ʻaʻole hiki i nā mea āpau ke loaʻa. Akā, ʻo kaʻoiaʻiʻo, aia nā pluses. Kūleʻa wau i nā mea āpau.

E loaʻa iaʻu ka maʻi diabetes 2. Hana ʻia ʻo ia, lawe i nā lāʻau lapaʻau i kēlā me kēia lā, akā ua hoʻemi ʻia ka glucose, a laila hoʻonui hou ʻia i 12 mau ʻāpana. Loaʻa nā hihia o ka hopena hypoglycemic, kahi pākeke ikaika i ka kō.

Ua kuhikuhi mai ke kauka iaʻu i kahi Vipidia. Ua hauʻoli nui wau i ka lāʻau lapaʻau. Hoʻohana wau i ka papa hoʻokahi i ke kakahiaka a he maʻamau nā mea āpau. ʻOiaiʻo ka uku kumukūʻai, akā, ʻaʻole wau ʻike ʻike i nā lula i nā ʻōkuhi koko a mālie i ka lā āpau.

Ua hāʻawi mai ke kauka i kahi papa hana no ka kūʻai ʻana i ka lāʻau lapaʻau "Vipidia". Ua nui wau i ka maʻi diabetes i nā makahiki he nui. Makemake wau i ka lāʻau lapaʻau, hoʻohaʻahaʻa loa ia i nā hōʻailona hōʻailona glucose. ʻO wau wale nō ke inu i ka lā.

ʻAʻohe contraindications inā e launa pū me nā lāʻau ʻē aʻe, e leʻaleʻa maikaʻi ʻia. ʻAʻole pili i ka psyche a ʻaʻole hoʻokū i ka hiamoe. Ke papa ʻole ʻia ana kahi kaʻa me ia.

Ua hauʻoli wau i nā mea āpau, kahi hopena lapaʻau maikaʻi ʻaʻole i hopena i kahi hopena noʻu.

ʻO nā papa Vipidia - nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana a me nā lāʻau lapaʻau like

ʻO ka maʻi maʻamau ʻo mellitus ka maʻi maʻamau. ʻO nā mea maʻi me kēia maʻi maʻi e hoʻomau mau i kā lākou koko koko a hoʻoponopono pono iā ia me ka lāʻau lapaʻau, ke ʻole inā hiki i ka hopena.

ʻO ia ke kumu he mea nui loa ka ʻike pehea o nā lāʻau lapaʻau i hoʻolālā ʻia e pale aku i nā ʻike o kēia hana maʻi. ʻO kekahi o lākou he Vipidia.

ʻIke ʻike lāʻau lapaʻau

E pili ana kēia mea hana i nā hana hou i loko o ke kahua o ka maʻi diabetes. He kūpono no nā poʻe i ka maʻi o ke ʻano maʻi type 2. Hiki iā Vipidia ke hoʻohana hoʻokahi wale nō a hui pū me nā lāʻau ʻē aʻe o kēia hui.

Pono ʻoe e hoʻomaopopo e hoʻohana ʻole ʻia ka hoʻohana ʻana i kēia lāʻau lapaʻau i ke ʻano o ka mea maʻi, no laila pono ʻoe e hahai pono i nā ʻōlelo a ke kauka. ʻAʻole hiki iā ʻoe ke hoʻohana i ka lāʻau lapaʻau me ke kī ʻole ʻana, ʻoiai inā lawe nā lāʻau lapaʻau.

ʻO ka inoa kālepa no kēia lāʻau lapaʻau ʻo Vipidia. I ka pae honua, ua hoʻohana ka inoa generikʻo Alogliptin, i puka mai i ka hana koʻikoʻi ma ka mana ona.

Hōʻike ʻia ka huahana e nā papa kiʻi ʻoniʻoni oval. Hiki iā lākou ke melemele a i ʻole nā ​​kukuiʻulaʻula (e hilinaʻi ia i ka dosage). ʻO ka pahu pahu ka 28 pcs. - 2 blisters no 14 papa.

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa ka lāʻau lapaʻau Vipidia ma Ireland. ʻO ke ʻano o kona hoʻokuʻu i nā papa papa. ʻElua mau ʻano, ʻelua ma muli o ka ʻike o ka mea hana - 12.5 a me 25 mg. ʻO nā papa me kahi liʻiliʻi o nā mea waiwai e loaʻa ai kahi kinipona melemele, me kahi nui nui - ʻulaʻula. Aia ma kēlā me kēia papa i kahi mau palapala e hōʻike ʻia ai ka hapa a me nā mea hana.

ʻO ke kumu hana nui o ka lāʻau ʻo Alogliptin Benzoate (17 a 34 paha i loko o kēlā me kēia papa). Ma kahi o ia mea, ua hoʻokomo ʻia nā mea kōkua i ka hoʻopili ʻana, e like me:

• mikuleka
• mannitol
• Hoʻopiʻi
• makee
• kahi sodium a ʻaihoe.

Aia nā ʻāpana i lalo nei i loko o ka poni kiʻiʻoniʻoni.

• titanium hone
• hypromellose 29104
• macrogol 8000,
• pulu ka melemele a i ʻole ʻulaʻula (hao wai).

Ka hana lāʻau lapaʻau

Kuhi ʻia kēia mea hana ma Alogliptin. ʻO kēia kekahi o nā mea hou i hoʻohana ʻia e kāohi ai i nā pae iʻa. Loaʻa ia ia i ka helu o ka hypoglycemic, he ikaika ikaika.

Ke hoʻohana ia, aia ka mahuahua o ka huna ʻana i ka huna glucose i ka wā e hoʻemi ana i ka hana glucagon inā hoʻonui ʻia ka nui o ke koko.

Me ka maʻi type 2, i hele pū ʻia me ka hyperglycemia, ke kōkua nei kēia mau hiʻohiʻona o Vipidia i nā loli maikaʻi e like me:

• ka hoʻemi ʻana o ka nui o ka hemoglobin glycated (НbА1С),
• hoʻohaʻahaʻa i nā pae glucose.

Hoʻohana kēia i kēia mea hana i ka mālama ʻana i ka maʻi diabetes.

Nā hōʻailona a me nā contraindications

Ke hōʻike nei i nā lāʻau ma loko o ka ikaika ikaika e mālama i ka mālama. Pono e mālama ʻia nā ʻōkuhi no lākou, inā ʻaʻole e hoʻopilikia ʻia ke kino o ka mea maʻi. No laila, hiki iā ʻoe ke hoʻohana iā Vipidia wale nō ma ka loiloi ʻana o kahi loea me ka mālama pono ʻana i nā ʻōkuhi.

Aine ʻia ke hāmeʻa no ka hoʻohana me nā maʻi diabetes type 2. Hāʻawi ia i nā hoʻoponopono o ka pae o ka glucose i nā hihia inā ʻaʻole i hoʻohana ʻia ka lāʻau lapaʻau a ʻokoʻa i ka hana kino pono. E hoʻohana pono i ka lāʻau no ka monotherapy. Ua ae ʻia iā ia me kona hoʻohana pū ʻia me nā lāʻau ʻē aʻe e kōkua i ka hoʻohaʻahaʻa haʻahaʻa.

ʻO ka hoʻomaʻamaʻa ʻana i ka wā e hoʻohana ai i kēia lāʻau lapaʻau maʻi mea i ka loaʻa ʻana o nā contraindications. Inā ʻaʻole i lawe ʻia i ka maikaʻi, ʻaʻole e ola ka mālama a mālama ʻia nā pilikia.

ʻAʻole ʻae ʻia ʻo Vipidia i kēia mau hihia:

• ka ʻana ʻole o kēia mau mea i nā ʻāpana o ka lāʻau lapaʻau,
• maʻi diabetes type 1
• hōʻeha paʻa ka naʻau
• maʻi ate
• hōʻeha maikaʻi o kaʻoki
• hapai a me lactation,
• ka hoʻomohala ʻana o ka ketoacidosis i kumu o ka maʻi maʻi,
• i ka 18 makahiki o ko ka mea maʻi.

ʻO kēia mau hōʻino he contraindications paʻa no ka hoʻohana ʻana.

Aia nō kekahi mau ʻōlelo e kuhikuhi pono ai ka lāʻau lapaʻau.

• lōkohu
• renal ka maʻi paʻakikī.

Eia kekahi, pono e mālama pono i ka mālama ʻana iā Vipidia me nā lāʻau ʻē aʻe e hoʻoponopono ai i nā pae glucose.

Nā hopena hopena

Ke mālama nei me kēia lāʻau lapaʻau, i kekahi mau manawa pōʻino e pili ana i nā hopena o ka lāʻau lapaʻau e hiki mai ana:

• lie kanikela
• nā maʻi hanu
• nasopharyngitis,
• ʻeha ka ʻōpū
• huu
• ʻili kino ʻili,
• maʻiʻo pancreatitis
• urticaria
• ka hoʻomohala ʻana o ka hana hema ʻana.

Inā hele nā ​​hopena ʻaoʻao, e kamaʻilio i kahi kauka. Inā ʻaʻole lākou i ka hanana hoʻoweliweli i ka olakino maʻi, a ʻaʻole hoʻonui i ko lākou ikaika, hiki ke hoʻomau ʻia ka mālama ʻana me Vipidia. ʻO ke kūlana koʻikoʻi o ka mea maʻi e haʻalele koke i ka lāʻau.

ʻ a me ke kākele

Kuhi ʻia kēia lāʻau lapaʻau no ka mālama ʻana i ka waha. Hoʻolilo ʻia ka nui o ka hewa ma muli o kēlā, e like me ka nui o ka maʻi, ka makahiki o ka mea maʻi, nā maʻi concomitant a me nā hiʻohiʻona ʻē aʻe.

I ka awelika, manaʻo e lawe i hoʻokahi papa i loaʻa he 25 mg o ka mea hana ikaika. Ke hoʻohana nei ʻo Vipidia i kahi waihona o 12,5 mg, ka nui o kēlā me kēia lā he 2 papa.

Hoʻomaopopo ʻia e lawe i ka lāʻau lapaʻau i hoʻokahi lā i ka lā. Pono e ʻawaʻawa ʻia nā paʻu ʻole me ka moʻoki ʻole. Manea ʻia e inu iā lākou me ka wai kuke. ʻAe ʻia ka ʻokoʻa ma mua o a ma hope o ka ʻai.

Mai hoʻohana i kahi pālua ʻelua o ka lāʻau lapaʻau inā ʻaʻole i hala kahi hoʻokahi - hiki i kēia ke hōʻeha. Pono ʻoe e lawe i ka maʻi maʻamau o ka lāʻau i ka wā e hiki mai ana.

ʻO ka hoʻomākaukau ʻana i kahi hana like

ʻOiai ʻaʻole loaʻa nā lāʻau e loaʻa i ke ʻano like a me ka hopena. Akā aia kekahi mau lāʻau lapaʻau e like me ke kumukūʻai, akā i hoʻokumu ʻia mai nā mea ikaika e hiki ai ke lawelawe me nā analog o Vipidia.

E pili ana kēia:

1. Januvia.Ui ʻia kēia lāʻau lapaʻau e hoʻemi i ke kō koko. ʻO ka mea hoʻonāola ka sitagliptin. Ua kuhikuhi ʻia ia ma nā hihia like me Vipidia.
2. Galvus. ^ E Ha yM. Hoʻokumu ʻia ka lāʻau lapaʻau ma Vildagliptin. ʻO kēia ʻano he mea hoʻohālike o Alogliptin a me nā mea like.
3. Janumet. ^ E Ha yM. ʻO kēia kahi hui i hoʻohui pū me ka hopena hypoglycemic. ʻO nā mea nui, ʻo Metformin a me Sitagliptin.

Hiki i nā lāʻau lapaʻau ke hāʻawi aku i nā lāʻau lapaʻau e hoʻololi hou iā Vipidia. No laila, ʻaʻole pono e hūnā mai ke kauka i nā loli lōlō i loko o ke kino e pili ana me kāna hana.

ʻO nā manaʻo hoʻomanawanui

Mai nā loiloi o nā mea maʻi e lawe ana iā Vipidia, hiki ke hoʻoholo ʻia e hoʻomanawanui maikaʻi nā papa a kōkua i ka mālama ʻana i ke kō o ke koko, akā pono e hana pono ʻia lākou e like me nā kuhikuhi, a laila uaʻike nā hopena kūpono a ʻohiʻohi.

Nā wikiō wikiō i nā kumu, nā hōʻailona a me ka mālama ʻana i ka maʻi diabetes:

Hiki ke ʻano ke kumukūʻai o Vipidia i nā lāʻau lapaʻau ma nā kūlanakauhale ʻē aʻe. ʻO ke kumukūʻai o kēia lāʻau lapaʻau ma loko o kahi waihonaʻauʻau o 12.5 mg i hoʻololi mai ka 900 a 1050 mau rubles. Ke kūʻai nei i kahi lāʻau lapaʻau me kahi hapa o 25 mg e kūʻai pono aku - mai ka 1100 a i 1400 rubles.

E mālama i ka lāʻau lapaʻau i nā wahi i hiki ʻole i nā keiki. ʻAʻole ʻae ʻia ka lā a me ka māla ma luna o ia. ʻAʻole pono nā pale i ka mālama ʻana ma mua o 25 mau kiʻekiʻe. 3 mau makahiki ma hope o ka hoʻokuʻu ʻia ʻana, ka pau ʻana o ka lā i ka lā.

Manaʻo mākou i nā ʻatikala e pili ana

Vipidia: he aha kēia mau lāʻau a pehea e kōkua ai lākou i ka maʻi maʻi

ʻO Vipidia kekahi o nā lāʻau lapaʻau no ka hōʻoki ʻana o ka waha ma ke ʻano maʻi diabetes ʻano 2. Hiki ke hoʻohana pū ʻia ʻelua, ʻo ia hoʻi, no ka monotherapy, a me ka hoʻohui pū ʻana me nā lāʻau lapaʻau ʻē aʻe.

ʻO ka mea hana - ka alogliptin, no kekahi hanauna hou, he mea e hui ana i ka pūʻulu o ka mimetin mimetics. Ua pane lākou i ka ʻai kai ma o ka hoʻoulu ʻana i ka hana ʻana i ka insulin.

Loaʻa nā papa Vipidia no ka maʻi maʻi i nā loiloi maikaʻi, ʻo ia no ka kiʻekiʻe a me ka maikaʻi o ka lāʻau.

ʻO nā hōʻailona nui a me nā contraindications

ʻO ka mea ikaika a Vipidia selly pili i ka dipeptidyl peptidase-4 (DPP-4). Hana pinepine nā ʻatikala i nā hana ʻino, i hōʻike ʻia ma ka hopena o ka mālama ʻana.

ʻO ka hala o ke ola o kēia huahana he ʻekolu mau makahiki, ma hope o ka mea ʻaʻole e koi ʻia e hoʻohana ia.

Pono ʻoe e mālama i ka lāʻau lapaʻau ma kahi kahi i pili ʻole ai me ka lā, ʻaʻole hoʻi ka wela i ka 25 tikelima.

ʻO Vipidia kahi lāʻau lapaʻau papaʻi e hoʻohaʻahaʻa i ke kōpaʻa koko. Hoʻohana ʻia ia ma ka mālama ʻana i ka maʻi diabetes type 2.

Manaʻo ʻia e hoʻomaka i ka lawe ʻana i ka wā e pau ai nā koi i ka papa ʻaina me ka hana hoʻoikaika kino i hāʻawi i ka hopena i makemake ʻia.

Hāʻawi ia e hoʻohana ma ke ʻano he monotherapy, hoʻopihapiha hoʻopili ʻia me nā lāʻau ʻē aʻe i pihi ʻia, me ke ʻano pū me ka insulin.

Aia kekahi mau contraindications e lawe i kēia lāʻau lapaʻau.

1. ʻO ka heleʻana o kahi hopena alerine a i ʻole kekahi mea hypersensitivity o ka mea ikaika a me nā mea kōkua o Vipidia.
2. ʻAno maʻi type 1.
3. ʻO nā maʻi o ka pupū o ka metabolism - ka ketosis, ka hoʻokūkū ākea hyperglycemic, hypoglycemia.
4. Holo ʻole ka huehue.
5. ʻO nā kaʻina pili pathological o ka ate, i hele pū me kāna hana ʻole.
6. ʻO nā maʻi ʻeha me ka pani ʻole.
7. ʻO ka wā hāpai, lactation.
8. Ke pāpā ʻia ʻole ʻia nā poʻe ma lalo o 18 mau makahiki.

Me ka mālama a ma lalo o ka mālama mālama olakino, hoʻohā ʻia ka lāʻau lapaʻau inā he maʻi a he maʻi pancreatitis paʻa ʻole, a me ka hana pōkole o ka pūpū a me ka ate. Ke hoʻohana nei ʻo Vipidia ma ke ʻano o ka lāʻau paʻakikī i nā lāʻau lapaʻau ʻē aʻe, e pono hoʻi e ʻike pono kā lākou hui.

E heluhelu pū i ka mea āu e pono ai ke ʻike e pili ana i ka mālama ʻana i ka maʻi maʻamau a me ka type 2.

Loaʻa nā hopena maikaʻi loa

Ke lawe nei i kēia lāʻau lapaʻau, hiki i kekahi mau hopena kūpono ke ulu.

1. Hoʻouna ka ʻōnaehana o ka ʻōnaehana me ka hoʻomohala ʻana i nā poʻo.
2. Hiki i ka ʻōnaehana hana ke pane me ka nānā ʻana o ke kinohi gastroesophageal, ʻeha i ka ʻāina epigastric, a me ka hoʻomaʻamaʻa ʻana hoʻi o ka pancreatitis.
3. I kekahi mau hihia, aia kekahi hewaʻole o ka hana maʻamau o ka nui o ka ʻōpū, ka puhaka.
4. ʻO ka hoʻonāukiuki o ka oropharynx.
5. ʻO kekahi o nā hopena maikaʻi loa hiki ke lilo i ka hopena alakania, ka mea i hōʻike ʻia e ka minamina, ka palena o Quincke, urticaria.

ʻAʻole loaʻa pinepine ka phenomena o ka anaphylaxis, akā eia kekahi mea.

Inā mākou e kamaʻilio e pili ana iā Vipidia me ka maka ma nā loiloi i waiho ʻia e nā poʻe maʻi e hoʻohana ana i kēia lāʻau lapaʻau, hiki iā mākou ke manaʻo e koʻikoʻi loa ia me ka maʻi diabetes type 2. Hiki iā ʻoe ke hoʻokō maikaʻi i ka maʻi mai, hoʻopaʻa i ka ʻike glycemic, hoʻēmi i ka hemoglobin glycosylated, e hōʻike ana i ka pono o kekahi ʻoihana.

Heluhelu pū kekahi He pōʻino paha i ka pōloli me ka maʻi maʻamau ʻo ka maʻi 2

He ʻanuʻu kūʻokoʻa kēia ʻaʻohe o nā mea hoʻohālike e like me kēia lā. ʻO ia, i loko o ka honua ʻaʻohe o nā lāʻau āpau e hoʻohana nui ana i ka alogliptin.

Eia nō naʻe, he nui nā lāʻau lapaʻau e pili ana i ka incretomimetics. Ua manaʻo ʻia lākou he mea hoʻohālikelike o Vipidia, a me kona mau mea hoʻokūkū ma ka mākeke lāʻau. ʻO nā mea kaulana loa a kaulana i nā ʻāina ʻē aʻe paha.

ʻO kāna ʻano hana sitagliptin. Hoʻokuʻu ʻia ka lāʻau i nā papa, dosages of 25, 50, 100 milligrams. Aia ia he mau hōʻailona like me ka vipidia, ʻoiai e hoʻohana ʻia ma ke ʻano he monotherapy a i hoʻohui pū ʻia me nā mea ʻē aʻe.

ʻO kēia kahi hui hoʻomākaukau e o ʻOviavia, ka hui pū ʻana o ia pū kekahi me Metformin. ʻO ka nui o ka sitagliptin he 50 milligrams, hiki i ka metformin ke piʻi me nā ʻekolu like ʻole - 500, 850 a i ʻole 1000 milligrams.

ʻO ia nō hoʻi kahi lāʻau i hoʻohui ʻia e pili ana i ka vildagliptin (i like pū me ka alogliptin) me ka metformin. ʻO nā Dosages nā like like me nā Yanumet.

Monopunaasi. ʻO ia ke kumu o ka saxagliptin hoʻāla ikaika. Aia ma kona ʻano, ua manaʻo ʻia he mea luku i nā incretins, ʻo ia hoʻi, he ʻano iki like ʻole o ka hana ma mua o Vipidia, akā aia i ka hui like o nā lāʻau. ʻO 2 nā 2,5 a me 5 mau milila.

Hoʻohui ka Combogliz

ʻO kēia lāʻau hōʻalo i hoʻohui ʻia me ka saxagliptin me nā metformin. Loaʻa ia i ka hopena lōʻihi ma muli o ka hoʻolohi lohi o nā mea hoʻoikaika.

I kēia lā, ʻo Vipidia ka lāʻau lapaʻau hou loa mai ka pūʻulu o ka mimetin mimetics. Ke hoʻohana nei kāna hoʻohana ʻana i nā hopena maikaʻi loa, a ʻo ke kumukūʻai no ke kūpono kūpono, ka mea i hala i ka manaʻo he nui nā endocrinologists e lawe i kēia lāʻau lapaʻau i ka lawelawe.

Nā hōʻailona no ka hoʻohana ʻana

ʻO Vipidia ka lāʻau maʻi hypoglycemic oral. Kuhi ʻia ia ma ke ʻano o nā papa oval o ka melemele a ʻulaʻula paha me kahi paʻi kamupene a me nā helu e hoʻoponopono ana i ka pau ʻana o ka hana ikaika.

Hoʻohana ʻia ka lāʻau lapaʻau i ke ʻano o nā papa, i hoʻolālā ʻia no nā koho dosage 2.

• nā papa i loaʻa ka alogliptin benzoate - 12.5 mg, kaomi i ʻoni,
• nā papa me ke kaola ikaika i ka nui o 25 mg - i ʻulaʻula.

Hoʻohana ʻia ka Vipidia no ka maʻi mellitus type II ma ke ʻano he lāʻau kūʻokoʻa a i ʻole pū me nā lāʻau ʻē aʻe e pili ana i ka hoʻemi ʻana i ke kō koko.

ʻO ka hana ikaika o ka lāʻau lapaʻau he hana hou e pili ana i ka incretinomimetics. ʻO kā lākou hana, ʻo ka hoʻāla ʻana i ke kino e hoʻokuʻu i ka insulin ma hope o ka ʻai ʻana. ʻO kēia pūlima o nā mea ʻona pū kekahi pūpū polypeptide a like me ka glucagon e like me ka polypeptide na glucose e hilinaʻi nei.

Hoʻololi ʻia ka Alogliptin e kona koho me ka mahalo i ka enzyme dipeptidyl peptidase-4. Hiki i ka mea hope ke hoʻopau i nā hormone mai ka pūʻulu o nā incretins me ka wikiwiki nui. Hiki ke hoʻopaʻaʻia lākou i loko o ka ʻōpū a ma, i ka wā ʻai, hāʻawi i ka hana i ka insulin i ka pancreas.

Hoʻopili i kahi peptide like me ka glucagon e like me ka hoʻohaʻahaʻa ʻana i ka nui o ka glucose i loko o ka ate. Me ka hoʻonui nui o ka incretins, kōkua ka alogliptin i ka hoʻonuiʻana i ka hana o ka insulin.

I ka manawa like, hōʻemi ka nui o ka glucagon e pili ana i ka mua o ka hoʻonui o ka glucose koko. Ke alakaʻi nei kēia mau kaʻina i ka emiʻana o ka nui o ka hemoglobin glycosylated i nā poʻe me ka maʻi ole-insulin-hilinaʻi.

Eia kekahi, hoʻonaninani ka nui o ka glucose koko ma luna o kahi ʻōpū ʻole a ma hope o ka saturation.

ʻO ka Vipidia ka mea lapaʻau e hoʻohana ʻia e hoʻomaikaʻi i ke ʻano o ka poʻe me ka maʻi type II. ʻO kāna hana nui, ʻo ka hoʻonui ʻana i ka pono o ka hoʻoponopono o ka glucose.

Hoʻohana ʻia ka lāʻau lapaʻau i ka wā a lawe ʻia ma ke alo. ʻO ka pilina momona holomua ʻo 25 mg. Lawe ʻia wale ia he 1 manawa i ka lā. Pōmaikaʻi ʻia ka papa ʻaina piha a holoi ʻia me ka wai anuanu maʻemaʻe.

Inā i loaʻa kēia, a laila e lawe i ka papa ʻelua i kēia mau lā a i ka lā ʻaʻole hiki ʻole. Pono e hoʻokō ʻia aku ka hoʻonui ʻia ʻana.

Inā hoʻohana pū ʻia ʻo Vipidia me metformin a i ʻole thiazolidinedione, a laila hiki ʻole ke hoʻololi hou aʻe i ka nui o ka lāʻau i lawe ʻia.

Hoʻololi wale ka hoʻololi ʻana i ka wai inā hana ʻia ka lāʻau lapaʻau me nā derivatives sulfonylurea a i ʻole me ka insulin e hōʻemi i ka hopena o ka hypoglycemia. Pono pono ka mālama kūikawā ma ka mālama ʻana me ka metformin a me thiazolidinedione. Inā hele mai nā hōʻailona o ka hypoglycemia, pono e hoʻemi ʻia ka ʻike o ka metformin a i ʻole thiazolidinedione.

Nā hoʻohālikelike o Vipidia

ʻO nā huahana o kahi lāʻau lapaʻau nā lāʻau e loaʻa ana i nā ʻano lāʻau like ʻole, akā hoʻohana ʻia e mālama i nā maʻi like me nā hōʻailona like.

Lā nō nā kikowaena Vipidia e pili ana i ka alogliptin. Eia nō naʻe, i ka hoʻomaʻamaʻaʻana i nā mea lapaʻau, nā loea therapeutic mai ka hui o ka incretin mimetics me kahi ʻano like ʻole e hoʻohana nui ʻia. Eia ka mea penei:

ʻO kēlā helu helu ʻākala e hōʻike i ka pili a me ka pono o nā lāʻau lapaʻau o kēia hana. ʻO nā loiloi e pili ana iā Vipidia a me nā hopena like loa he kūpono loa.

ʻO ka pilikia wale nō i nā lāʻau āpau i hoʻoponopono i ka hoʻopalike o ke kōhi koko i ka maʻi diabetes he nui nā contraindications a me nā hopena ʻaoʻao.

Eia kekahi, pono ka noi ʻana o kā lākou noi i ka kamaʻilio o ke kino, ke ʻano o nā maʻi ʻē aʻe, a koi ʻia hoʻi ka mālama pono ʻana ʻaʻole wale o ka kō koko, akā ke ʻano nei kekahi mau hōʻailona o ke kino.

ʻO ka lāʻau Hypoglycemic, kahi potent a me nā mea koho selipous maikaʻi loa o ka dipeptidyl peptidase-4 (DPP-4).

ʻO kona koho ma DPP-4 ʻoi aku ma mua o ka 10 mau manawa i ʻoi aku ma mua o ka hopena no ka ʻoliʻoli e pili ana, me ka DPP-8 a me DPP-9.

ʻO DPP-4 ka enzyme nui i hoʻopili ʻia i ka luku wikiwiki ʻana i nā hormone o ka ʻohana incretin: ʻO ke kupa e like me peptide-1 (GLP-1) a me ka glucose-e hilinaʻi i ka insulinotropic polypeptide (HIP).

Hoʻokomo ʻia nā huaʻelima o ka ʻohana incretin i loko o ka ʻōpū, hoʻonui ʻia ko lākou manaʻo i ka pane ʻana i ka ʻai o ka meaʻai. Hoʻonui ka GLP-1 a me HIP i ka synthesis o ka insulin a me kona neʻe ʻana e ka pancreatic β-cell.Hoʻopili hoʻi ka GLP-1 i ka mea huna glukagon a hoʻēmi i ka hana o ka glucose glucose.

No laila, hoʻonui i ke kāʻei o ka incretins, hoʻonui i ka alogliptin i ka huna ʻana i ka glucose o ka glucose a me ka hoʻokaʻawale i ka huna ʻana o ka glucagon me ka hoʻonui ʻia ʻana o ka glucose i loko o ke koko.

I ka poʻe maʻi me ka diabetes mellitus type 2 me ka hyperglycemia, ʻo kēia mau hoʻololi i ka ʻalilo ʻana o ka insulin a me ka glucoseagon e alakaʻi nei i ka kaohi ʻana o ka neʻe o gogemobobin glycosylated НbА1С a me ka hoʻohaʻahaʻa ʻana i ka ʻaina o ka glucose i loko o ke koko koko o ka wikiwiki a me ka hoʻoliʻi ʻana ma ka wā neʻe.

Vipidia - nā ʻōlelo aʻoaʻo no ka hoʻohana, nā analogues

1 papa 12.5 mg i loaʻa

ʻO ka waiwai waiwai: alogliptin benzoate - 17 mg (ma nā huaʻōlelo alogliptin - 12.5 mg).

ʻO ka waiwai koʻikoʻi: alogliptin benzoate - 34 mg (ma nā huaʻōlelo alogliptin -25 mg).

Nā mea hoʻoweliweli:
Nukleus: mannitol 79.7 mg, cellulose microcrystalline 22.5 mg, hyprolose 4,5 mg, croscarmellose sodium 7.5 mg, magnesium stearate 1,8 mg.

Ka uhi kiʻi ʻoniʻoni: hypromellose 2910 5.34 mg, titanium dioxide 0.6 mg, iron dye oxide red 0.06 mg, macrogol-8000 trace kālā, mauʻu hina loko F1 heʻeke ma ka helu 1.

ʻO keʻano
Nā ʻōpiopio 12.5 mg ʻO nā papa bvalvex oval, i kālai ʻia me kahi kāwele kiʻi melemele, me ke ʻano "TAK" a me "ALG-12.5" ma ka ʻaoʻao hoʻokahi.

ʻO ka ʻaihue hypoglycemic dipeptidyl peptidase-4 inhibitor (DPP-4).

Lapaʻau lāʻau

ʻO Alogliptin kahi lūlū paʻa a me ka mea nāna i koho maikaʻi loa ʻo DPP-4.

ʻO kona koho ma DPP-4 ʻoi aku ma mua o ka 10 mau manawa i ʻoi aku ma mua o ka hopena no ka ʻoliʻoli e pili ana, me ka DPP-8 a me DPP-9.

ʻO DPP-4 ka enzyme nui i hoʻopili ʻia i ka luku wikiwiki ʻana i nā hormone o ka ʻohana incretin: ʻO ke kupa e like me peptide-1 (GLP-1) a me ka glucose-e hilinaʻi i ka insulinotropic polypeptide (HIP).

Hoʻokomo ʻia nā huaʻelima o ka ʻohana incretin i loko o ka ʻōpū, hoʻonui ʻia ko lākou manaʻo i ka pane ʻana i ka ʻai o ka meaʻai. Hoʻonui ka GLP-1 a me HIP i ka synthesis o ka insulin a me kona neʻe ʻana e ka cell beta pancreatic. Hoʻopili hoʻi ka GLP-1 i ka mea huna glukagon a hoʻēmi i ka hana o ka glucose glucose.

No laila, hoʻonui i ke kāʻei o ka incretins, hoʻonui i ka alogliptin i ka huna ʻana i ka glucose o ka glucose a me ka hoʻokaʻawale i ka huna ʻana o ka glucagon me ka hoʻonui ʻia ʻana o ka glucose i loko o ke koko.

I ka poʻe maʻi me ka diabetes mellitus type 2 me ka hyperglycemia, ua hoʻololi kēia mau hoʻololi i ka huna ʻana o ka insulin a me ka glucagon i ka emi ʻana o ka kaʻe o ka glycosylated hemoglobin HbA1c a me ka emi ʻana o ka kaʻe o ka glucose i loko o ke kaila koko o ka wikiwiki a me ka hoʻoliʻi ʻana ma ka wā neʻe.

Lapaʻau lāʻau ʻO nā pharmacokinetics o alogliptin e like me nā mea olakino a me nā mea maʻi me nā maʻi maʻi type 2.

ʻO ka bioavailability piha o alogliptin e pili ana i ka 100%. ʻO ka hoʻohana pū me ka meaʻai momona nui ʻaʻole i pā i ka wahi ma lalo o ka pihi o ka konsentration-manawa (AUC) o ke alogliptin, no laila hiki ke lawe ʻia ʻole e like me ka pāʻina. I ka poʻe olakino olakino, ma hope o ka lawelawe waha hoʻokahi a hiki i ka 800 mg o ka alogliptin, ʻike pinepine ʻia ka hōʻemi ʻana i ka lāʻau me ka hiki ʻana i kahi pae kiʻekiʻe (average TCmax.) I ka pae mai 1 a 2 mau hola mai ka manawa o ka hoʻokō ʻana. ʻAʻole i ʻike pū kekahi na ka poʻe olakino olakino a me nā mea maʻi me ka maʻi diabetes mellitus type 2 i ka nui o ka hōʻiliʻili alogliptin ma hope o ka hoʻokele ʻana. AUC o ke alogliptin e hoʻonui me proportionally me kahi pākahi hoʻokahi i loko o ka hopena therapeutic pae mai 6.25 mg a 100 mg. ʻO ka loli nui o AUC o ka alogliptin i waena o nā mea maʻi e liʻiliʻi (17%). AUC (O-inf) o alogliptin ma hope o hoʻokahi dosis i like me AUC (0-24) ma hope o ka lawe ʻana i ia ka hopena like hoʻokahi i ka lā no 6 mau lā. Hōʻike kēia i ka nele o ka manawa hilinaʻi i ka kinetics o alogliptin ma hope o ka hoʻokele hou ʻana.

Ma hope o kahi hoʻomalu alogliptin kū hoʻokahi i kahi maʻi o 12.5 mg i nā limahana olakino, ʻo ka hoʻonui ʻana i ke kīpī ma ka pae terminal he 417 L, e hōʻike ana i ka alogliptin i hoʻolako maikaʻi ia i nā kiko. ʻO ke kamaʻilio me ka protein protein e like me 20-30%.

ʻAʻole i hoʻohālikelike ʻia ʻo Alogliptin i ka metabolism kūlohelohe, mai 60 a 70% o ka alogliptin e hoʻopili ʻia nei e nā loli.

Ma hope o ka hoʻomoe ʻana o ka alogliptin hōʻailona 14C i loko, ʻelua mauʻano metabolits nui i hoʻoholo ʻia: N-demethylated alogliptin, M-I (50 a 30 a hiki i ka 1/100, 1/1000, 1/10 000,