Diabefarm - nā ʻōlelo aʻoaʻo no ka hoʻohana

NA ININA
no ka hoʻohana lāʻau ʻana i ka lāʻau

Ka helu helu inoa:

Inoa kālepa: Diabefarm ®

Inoa Kūʻai ʻole honua: gliclazide

Pākuʻi helu: papa papa

Hōʻike:
1 papa i loaʻa
Mea waiwai: gliclazide 80 mg
Nā mea hoʻoweliweli: lactose monohydrate (nā waiū waiu), povidone, stearate magnesium.

ʻO keʻano
ʻO nā papa keʻokeʻo a keʻokeʻo paha me kahi kiko melemele i pālahalaha-cylindrical me kahi chamfer a me ka hopena o ke kūlike.

ʻĀpana Pharmacotherapeutic: ka lawena hypoglycemic no ka lawe waha waha o ka hui sulfonylurea o ka lua o ka hanauna

ʻĀkau ATX: A10VB09

Ka hana lāʻau lapaʻau
Lapaʻau lāʻau
Hoʻopuka ka Glyclazide i ka mea huna o ka insulin e ka pancreatic β-cell, hoʻonui i ka hopena o ka insulin-secretory o ka glucose, a hoʻonui i ka manaʻo o nā kolo peripheral i insulin. Hoʻowalewale i ka hana o nā kinipili intracellular - kūlohelohe glycogen synthetase. Hoʻēmi i ka manawa manawa mai ka manawa o ka ʻai ʻana a i ka hoʻomaka ʻana o ka huna ʻana i ka insulin. Hoʻihoʻi ia i ka mua o ke kinikini o ka huna ʻia o ka insulin (e like me nā derony e pili ana i ka sulfonylurea, he hopena ia ma ka lua o ke kaha o ka noho ʻōlelo. Hoʻemi i ka hoʻonui ʻana ma hope o ka glucose i ke koko.
Hoʻopili i nā mea pili i ka metabolism, ke hoʻoneʻe ʻana i ka microcirculation: hōʻemi ia i ka platelet adhesion a me ka hōʻuluʻulu ʻana, hoʻāla ʻia ka vascular permeability, pale i ka hoʻomohala ʻana o ka microthrombosis a me atherosclerosis, a hoʻihoʻi i ke kaʻina o ka physietie parietal fibrinolysis. Hoʻēmi i ka maʻi receptor vascular i ka adrenaline. Hoʻowalewale i ka hoʻomohala ʻana o ka retinopathy maʻi i ka pae ieproliferative. Me ka nephropathy diabetic me kahi hoʻohana lōʻihi, aia ka nui o ka hōʻemi o ka nui o ka proteinuria. ʻAʻole ia e alakaʻi i ka hoʻonui nui o ke kaumaha kino, no ka mea aia kahi hopena nui ma ka wī o ka neʻe o ka huna ʻana o ka insulin a ʻaʻole ia e hoʻoulu i ka hyperinsulinemia, ke kōkua i ka hoʻemi ʻana o ke kaumaha o ke kino i nā mea maʻi e kau a me nā meaʻai kūpono. Loaʻa ia mau waiwai anti-atherogenic, hoʻohaʻahaʻa i ke kahe o ke kolamu ma ka koko.
Lapaʻau lāʻau
Ma hope o ka lawelawe waha, ua wikiwiki koke ʻo ia ma ka gastrointestinal tract. He kiʻekiʻe nā Absorption. Ma hope o ka hoʻokō ʻana o ka waha o 80 mg, ua hoʻokō ka nui o ke koʻo i ke koko (2.2-8 mlg / ml) ma hope o ka hola 4, ma hope o ka lawelawe ʻana o 40 mg, ʻo ka nui o ka piʻi ʻana o ke koko (2-3 μg / ml) i loaʻa ma hope o 2-3 mau hola. me nā protein o ka plasma - 85-97%, pālahalaha ka helu - 0.35 l / kg. Loaʻa ka paʻa kūpapa o ke koko ma hope o 2 mau lā. Hoʻomili ʻia ia i ka puʻu, me ka hoʻokumu ʻana o 8 mau metabolites.
ʻO ka nui o ka metabolite koʻikoʻi i loaʻa i ke koko he 2-3% o ka nui o ka lāʻau i lawe ʻia, ʻaʻole ia he hopena hypoglycemic, akā e hoʻomaikaʻi ai i ka microcirculation. Hoʻokuʻu ʻia ia e nā pōpoki - 70% i ke ʻano o nā metabolites, hōʻemi ma mua o 1% i kahi ʻano loli ʻole, ma o nā ʻōpū - 12% i loko o ke ʻano o nā metabolites.
ʻO ka hapalua-ola kahi 8 a 20 mau hola.

Nā hōʻailona no ka hoʻohana ʻana
ʻO ka maʻi mellitus type 2 i ka pākeke me ka hui ʻana me ka lāʻau lapaʻau a me ka hana kino maʻalahi me ka hopena ʻole.

Nā Hoʻohui
Hypersensitivity ki ka lāʻau lapaʻau, type 1 diabetes mellitus, ketoacidosis diabia, precoma diabetes, coma maʻi, comos hyperosmolar, hepatic koʻikoʻi a / a i ʻole renal failed, major surgical interventions, broad burn, ʻeha and other and requirements in order nangangailangan insulin therapy, intestinal obstruction, paresis ʻōpū, nā kūlana me ka malabsorption o ka meaʻai, ka hoʻomohala ʻana o ka hypoglycemia (nā maʻi ʻeha), leukopenia, hapai, hānai, keiki ozrast i ka makahiki 18.

Me ka mālama pono (ka pono no ka mālama pono ʻana me ka koho ʻana i ka inea) i ʻōlelo ʻia no ka febrile syndrome, ka ʻalohi a me nā maʻi thyroid (me ka hana kīnā ʻole).

Hoʻohana i ka wā hāpai a me ka lactation
Hoʻokomo ʻia ka lāʻau lapaʻau i ka wā hāpai a i ka wā hānai.
Ke ulu mai ka wā hānau, pono e hoʻokuʻu koke i ka lāʻau.

ʻ a me ke kākele
Hoʻonohonoho ʻia ka nui o ka lāʻau lapaʻau kū hoʻokahi, e pili ana i ka makahiki o ka mea maʻi, ka hōʻike kino o ka maʻi a me ka pae o ka wikiwiki o ka glucose koko a me nā hola 2 ma hope o ka ʻai. ʻO ka inikua mua o kēlā me kēia lā he 80 mg, ka awelika o ka helu maʻamau o kēlā me kēia lā he 160 mg, a me ka dosis nui loa o kēlā me kēia lā he 320 mg. Lawe ʻia ka diabefarm i ʻelua mau manawa i ka lā (kakahiaka a me ke ahiahi) 30-60 mau minuke ma mua o ka papaʻaina.

Loaʻa ka hopena
Hypoglycemia (i ka hihia o ka hoʻoponopono hewa ʻana o ka hoʻoponopono a me ka ʻole o ka ʻai): ʻeha, ka ʻeha, ka pōloli, ka luhiluhi, ka nāwaliwali nui, ka luhi, ka hopohopo, ka huhū, ka hoʻokaʻawale ʻana a me ke kūpaʻa ʻana i ka maʻi, ke kaumaha, ka hōʻino ʻana o ke ʻano, ka aphasia, ka haunaele ka nalowale ʻana o ka hoʻopaʻa i ka hoʻokele ponoʻī, delirium, confulsions, hypersomnia, nalowale o ka ʻike, papalū ea, bradycardia.
Nā maʻi kūwaha: itching, urticaria, maculopapular rash.
Mai nā ʻekopa hemopoietic: anemia, thrombocytopenia, leukopenia.
Mai ka pūnaehana hana ʻana: dyspepsia (pōhaʻi, ʻeha, ʻeha kaumaha i loko o ka epigastrium), anorexia - hoʻēmi ka kaumaha i ka wā i lawe ʻia me ka meaʻai, ka hana like ʻole a ka lolo (cholestatic jaundice, nui aʻe o ka hana o ka "ate" transaminases).

Ke keu
Nā hōʻailona: hiki i ka hypoglycemia, a hiki i ke kūkuluʻana i ka coma hypoglycemic.
Hoʻomaʻamaʻa: inā ua ʻike ka mea maʻi, e lawe maʻalahi i nā kao (digestible glucose) i loko, me ka pilikia o ka ʻike, 40% dextrose (glucose) e mālama ʻia i ka hana intravenously, 1-2 mg o glucagon intramuscularly. Ma hope o ka ʻike hou ʻana, pono e hāʻawi ka mea maʻi i ka meaʻai i ka momona digestible maʻalahi (i mea e pale ʻole ai ka hana hou o ka hypoglycemia). Me ka edema utak, mannitol a me dexamethasone.

Hoʻopili pū me nā lāʻau ʻē aʻe
ʻO Angiotensin-hoʻohuli i ka hoʻōla o ka enzyme (captopril, enalapril), H2-histamine receptor blockers (cimetidine), nā lāʻau antifungal (miconazole, fluconazole), nā mea hoʻohana anti-inflammatory anti-inflammatory (phenylbutazoflubrate, indigo), e kāohi ana i ka hopena hypoglycemic o Diabefarma (ethionamide), nā salicylates, Coumarin anticoagulants, anabolic steroid, beta-blockers, cyclophosphamide, chloramphenicol, monoamine oxidase inhibitors, su fanilamidy hooloihiia hana, fenfluramine, fluoxetine, pentoxifylline, guanethidine, theophylline, ai 'e aeie omo secretion, reserpine, bromocriptine, disopyramide, pyridoxine, allopurinol, ethanol a me ka etanolsoderzhaschie hoomakaukau, e like me nā hypoglycemic ai' (acarbose, biguanides, insulina).
Weyed the hypoglycemic effects of Diabefarma barbiturates, glucocorticosteroids, sympathomimetics (epinephrine, clonidine, ritodrine, salbutamol, terbutaline), phenytoin, blockers channel kalsium, inhibitor dehydrase carbonic, thiazide azolefenudenate, triaidide azolefenudenate, triazide azolefenudenate, triazide azolefenudenate, triazide azolefenudenate , diazoxide, isoniazid, morphine, glucagon, rifampicin, thyroid hormones, lithium salts, i nā koina nui - nā waikeka nikotinic, chlorpromazine, estrogens a me nā contraceptive waha e loaʻa ana iā lākou.
I ka wā e launa pū me etanol, hiki i kahi hopena disulfiram-like.
Hoʻonui ʻo Diabefarm i ka hopena o ka ventricular extrasystole aʻo ka lawe ʻana i nā glycosides cardiac.
Hiki i nā beta-blockers, clonidine, reserpine, guanethidine ke uhi i nā hōʻike kino o ka hypoglycemia.
ʻO nā lāʻau lapaʻau e pale i ka hematopoiesis pumehana o ka iwi e hoʻonui i ka hopena o ka myelosuppression.

Nā ʻōlelo kikoʻī
Ke lawe nei ka hana diabefarm i ka hui pū me kahi meaʻai haʻahaʻa-low, a me ka lāʻau haʻahaʻa. Pono e kiaʻi pinepine i ka ʻike o ka glucose i loko o ke koko ma kahi ʻōpū ʻole a ma hope o ka ʻai.
I ka hihia o nā mea hoʻoweliweli a me ka hoʻokaʻawale ʻana i ka maʻi diabetes, pono pono e noʻonoʻo pono i ka hoʻohana ʻana o ka hoʻomākaukau ʻana i ka insulin.
Pono e lapatai i nā maʻi e pili ana i ka hoʻonui nui o ka hypoglycemia i ka hihia e lawe ai i ka ethanol, non-steroidal anti-inflammatory drug, pololi. I loko o ka hihia o ka ethanol, hiki nō i ka hoʻomohala ʻana i kahi maʻi disulfiram-like (ʻeha o ka ʻōpū, ke kala ʻana, ka hoʻohua ʻana, a me ke poʻo).
Pono e hoʻoponopono i ka palena o ka lāʻau lapaʻau me ke koʻikoʻi a i ʻole ka naʻau, ke hoʻololi ʻana i ka ʻai
Hoʻomaʻamaʻa koʻikoʻi i ka hana o nā lāʻau hypoglycemic mea nā kānaka makua, nā mea maʻi e loaʻa ʻole i ka ʻai kaulike, nāwaliwali nāwaliwali, nā mea maʻi e loaʻa nei i ka maʻi o ka pituitary-adrenal.
I ka hoʻomaka ʻana o ka mālama ʻana, i ka wā e koho ai i ka nui o nā maʻi, ʻike ʻia nā mea maʻi i ka hoʻomohala ʻana o ka hypoglycemia, ʻaʻole i ʻōlelo ʻia e hana i nā hana e koi ai i ka piʻi nui a me ka wikiwiki o ka hopena psychomotor.

E hoʻokuʻu i ke ʻano
80 papa papa
Ma nā papa he 10 i loko o kahi pale polū blister mai kahi kiʻi o polyvinyl chloride a me kahi alumini foil i paʻi ʻia ua varnished.
3 a 6 mau blister paha me nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana e waiho ʻia i loko o kahi kīpē.

Nā kūlana mālama
Papa inoa B. I kahi maloʻo malū a maloʻo ma kahi mahana kiʻekiʻe ʻole ma mua o 25 ° C.
Mai mālama i nā keiki.

ʻO ka lā kau
2 makahiki
Mai hoʻohana ma hope o ka lā pau.

Hoʻohui Kūʻai Kūʻai
Ma ke kumu.

Pono e hoʻopili i nā hoʻopiʻi i ka mea hana:
FARMAKOR PRODUCTION LLC, Rusia
Koho Hana
198216, St. Petersburg, Leninsky Prospect, d.140, lit. P
Wā i kū kānāwai:
194021, St. Petersburg, 2nd Murinsky Prospect, 41, lit. A