Berlition 600 papa: nā ʻōlelo no ka hoʻohana ʻana

mea waiwai - thioctic acid 600 mg

nā mea hoʻowalewale: momona momona, medium chain triglycerides.

ʻili: ʻO 70% solution sorbitol, ʻaʻohe crystallizing (ma hua ʻōlelo o ka anhiddrous), 85% glycerin (ma nā huaʻōlelo o ka anhiddrous), gelatin, titanium dioxide (E 171), carmine varnish (E 120).

ʻO nā waiwai Pharmacological

I nā kāne, ua hopu koke ka acid thioctic ma hope o ka lawelawe waha. Ma muli o ka hopena o ka hopena o ka pau mua ma ka palani ʻana, ʻoi loa ka bioavailability (e hoʻohālikelike ʻia me ka hoʻomalu iv) o ka wai thioctic i lawe ʻia. 20% Ma muli o ka lawe wikiwiki ʻana i nā kiko, ʻo ka hapalua o ka ola o ka wa thioctic mai ka plasma i ke kanaka e like me 25 mau minuke.

ʻO ka bioavailability o ka waika thioctic i ka wa e lawe ʻia ai i ka maʻi maʻamau i nā puka pānaʻi ʻoi aku ka nui ma mua o 60% e pili ana i nā hopena kūlohelohe. Ka kiʻekiʻe loa e pili ana i ka plasma like. 4 mcg / ml, loaʻa ma hope o ka mea. 0,5 h ma hope o ka hoʻomoʻa waha ʻana o 600 mg o ka lāʻau thioctic.

I nā hoʻokolohua ma luna o nā holoholona (ʻo nāu, nā ʻīlio), me ka hoʻohana ʻana i ka leki uila, hiki ke hoʻomaopopo ʻia i ke ala o ka ala o ka excretion (80-90%), ʻo ia hoʻi, ma ke ʻano o nā metabolites. I nā kāne, loaʻa nā waihona waiwai i loko o ka urine wale nō. ʻO Biotransformation ka hapanui o ka hoʻomehana ʻana o ka pōkole o ka mekala o ka ʻaoʻao (beta oxidation) a me / a i ʻole S-methylation o nā thiols pono.

Ua pane ka wai waikila Thioctic i ka vitro me nā paona konohona (e.g. cisplatin). Hoʻokomo ʻia nā Thioctic acid me nā molekoli i loko o nā pūnaehana paʻakikī sparingly.

Lapaʻau lāʻau

ʻO ka wai Thioctic he huaʻai i ka like bitine akā akā endogenous e hana ana e like me ka coenzyme i loko o ka decarboxylation oxidative o nā waika alpha-keto. Hyperglycemia i kumu o ka diabetes mellitus alakaʻi i ka hoʻoili ʻia o ka glucose i ka protein matrix o nā kīʻaha koko a me ka hoʻokumu ʻana o nā huahana hopena o ka glycosylation holomua ("Advanced Glycosylation End Products"). Ke alakaʻi nei kēia kaʻina i ka hoʻemi ʻana i ke kahe koko endoneural a i ka endoneural hypoxia / ischemia, ka mea i hui pū ʻia me ka hoʻonui nui ʻana o nā ʻāpana oxygen hāmeʻa e hōʻino i nā kino peripheral. I loko o nā nīnipoli peripheral, ua loaʻa hoʻi i ka antiioxidants, e like me glutathione. Hōʻike nā hōʻike hōʻike e pili ana ka asi thioctic i kēia mau hana biochemical, e hōʻemi ana i ka hoʻokumu ʻana o nā huahana glycosylation hope, hoʻomaikaʻi i ka kahe koko endoneural, a me ka hoʻonui ʻana i nā pae o ka physiological o nā antioxidant glutathione. Hoʻohana ʻia ʻo ia nō ka hana antioxidant e kū'ē i nā radical free oxygen i nā ʻeha i hoʻopilikia ʻia e ka maʻi maʻi. Kuhi kēia mau hopena i ka wā o ka hoʻokolohua e hōʻike ʻia me ke kōkua o thioctic acid, hiki ke hoʻomaikaʻi ʻia ka hana o nā niperi peripheral. Pili ka pili i nā maʻi maʻi ma ka maʻi polyneuropathy maʻi, hiki iā ia ke hōʻike me ka dysesthesia a me ka paresthesia (no ka laʻana, ʻāwīwī, ʻeha, hōʻeha a hoʻoluhi paha). Hōʻike nā haʻawina haukapila i nā hopena pono e loaʻa ana i ka wai thioctic i loko o ka hōʻailona hōʻailona o ka polyneuropathy maʻi, i hele pū ʻia e nā ʻike kaulana e like me ka puhi ʻana, paresthesia, ʻeha a me nā ʻeha.

Pharmacodynamics a me ka pharmacokinetics

Hoʻomoʻa ʻo Berlition i kahi mea hoʻoikaika mau ka thioctic acid (ʻhalelo alpha lipoic) i ka hana o ka paʻakai ethylene diamine, kahi mea antioxidant endogenous e hoʻopaʻa ana i nā radical free me kahi coenzyme o nā kaʻina decarboxylation alpha-keto acid.

Hoʻopili i ka hoʻomaʻemaʻe Berlition i nā pae o ka plasma. kekuhi a hoonui i ka puuwai glycogennāwaliwali Ke kū'ē i ka insulin, e hoowalewale i ka cholesterol, e hoʻoponopono i nā lipid a me ka hoʻoliʻiliʻi o ka hana ʻaina. Thioctic acidMa muli o kāna hana antioxidant waiwai, pale iā ia i nā pūpela o ke kino o ke kanaka mai nā pōʻino i kumu ʻia o ko lākou huahana decay.

I nā maʻi maʻi maʻi hoʻemi ka thioctic acid i ka hoʻokuʻu o nā huahana hope glycation protein i loko o nā wahī neʻe, hoʻonui i ka microcirculation a hoʻomaikaʻi i ke kahe koko endoneural, hoʻonui i ka ʻike kino antioxidant glutathione. ^ E Ha yM. Ma muli o kona hiki ke hoʻemi i ka haʻuki glucose i ka plasma, pili ia i kahi ala kola o kāna metabolism.

ʻO ka hoʻōho Thioctic e hōʻemi i ka hōʻemi o ka pathological nā metabolites polyol, a laila hiki i ka hoʻopiʻi ʻana i ka hōʻemi ʻana o ka ʻōpū o ka aʻa. Hoʻohālikelike i ka laweʻana o nā mea hoʻonāuki a me ka hoʻōla o ka ikehu. Ke komo nei i ka metabolism momona, hoʻonui i ka biosynthesis ka phospholipidsma muli o kahi o ka hana poino o nā membrane ke hoʻoponopono ʻia. Hoʻopau nā hopena makeʻa hale huahana waiʻona (pyruvic waikawa, acetaldehyde), hōʻemi i ka hoʻokuʻu ʻana o ka oxygen keu molumika manuahi a hoʻemi ʻia ischemia a me ka endoneural hypoxianā hoʻemi hoʻohālikelike polyneuropathyi ke ano alohapuhi kuni ʻana hoʻi, nā ʻū a me nā ʻeha i loko o ka wāwae.

Ma muli o ka mea i hōʻike ʻia ma mua, ke ʻano like me ka lāʻau thioctic ma kāna hypoglycemic, neurotrophic a me nā hana antioxidant, me ka hoʻomaikaʻi ʻana lipid metabolism hana. Hoʻohana ma ka hoʻomākaukau ʻana i ka mea kanu ikaika i ke ʻano paʻilima Ethylene hiki iā ʻoe ke hōʻemi i ka nui o nā hopena maikaʻi ʻole o ka waika thioctic.

Ke lawe waha ʻia, hoʻohuihui koke ʻia nā kiki thioctic a mai loko mai o ka digestive tract (ʻo ka ʻai i hoʻokaʻawale ʻia e hoʻokaʻawale i ke komo ʻana). ʻ varieslelo nā TCmax i ka plasma i waena o 25-60 mau minuke (me ka lula kikowaena o 10-11 mau minuke). ʻO Plasma Cmax kahi 25-38 mcg / ml. Bioavailability o kahi 30%, Vd o like me 450 ml / kg, AUC o ke aniani o 5 μg / h / ml.

Ua hoʻohālikelike ʻia ka Thioctic acid ma kahi "first pass" ma o ke ake. Wehewehe metabolic huahana i hiki i ke kaʻina hana konohonui a ʻaoʻao kaulahao. ^ E Ha yM. ʻO ka hana ma ke ʻano o nā metabolites he 80-90% e lawe ʻia ana e nā keiki. Hopu ʻia ʻo T1 / 2 ma kahi o 25 mau minuke. ʻO ka huina piha piha plasma he 10-15 ml / min / kg.

Nā Hoʻohui

Contendicated ʻo Berlition i nā poʻe maʻi ma lalo o ka 18 mau makahiki o nā makahiki, nā mea maʻi me ka hypersensitivity pilikino i ka mea ikaika (thioctic acid) a i ʻole kekahi o nā mea kōkua o ka hana o ka lāʻau lapaʻau o ka lāʻau, a me ka wahine lactating a me nā wahine hāpai.

Berlition 300 papa, ma muli o ke alo i kēia ʻano lactosecontraindicated i nā maʻi me kekahi hoʻoilina aloha gula.

No nā ʻano āpau a pau o ka lāʻau lapaʻau

• kue / loli i ka hoʻāʻo,
• hōʻemi i ka plasma ʻikepilikekuhi (ma muli o ka hoʻomaikaʻi ʻana o kona ʻike),
• aaeana hypoglycemiame ke komo kino ʻana, āhāhuʻe, hipogekisisis, poʻomanaʻo,
• nā mea hoʻonāukiukikomo pū ka ʻili he wahi pehi/huukalakaʻi urticaria (urticaria), anaphylactic pīhoihoi (i nā hihia kūʻokoʻa).

Hoʻopiliʻia no nā ʻano makua makua o ka lāʻau lapaʻau

• diplopia,
• wela
• nahoa,
• thrombocytopathy,
• purpura
• ʻaʻano pōkole a hoonui kaomi intracranial (i ʻike ʻia i nā hihia o ka hoʻokele wikiwiki a kū i kēlā me kēia manawa).

Berlition, nā ʻōlelo no ka hoʻohana ʻana (Ke ʻano a me ke ʻano)

Kahi kuʻina mana no ka hoʻohana ʻana i ka Berlition 300 i like nā ʻōlelo i ka hoʻohana ʻana i ka Berlition 600 no nā ala āpau o nā lāʻau lapaʻau (hoʻonāukiuki, capsules, nā papa).

ʻO ka lāʻau lapaʻau Berlition i manaʻo ʻia no ka hoʻomākaukau ʻana i nā infusions i kuhikuhi mua ʻia i loko o kahi lā o kēlā me kēia lā he 300-600 mg, e mālama ʻia ana i kēlā me kēia lā i loko o kahi paʻu no ka liʻiliʻi he 30 mau minuke, no 2 mau wiki. Ma mua o ka kuhiʻana, ua hoʻomākaukau ʻia kahi hopena lapaʻau me ka hoʻopili ʻana i nā kiko o 1 ampoule o 300 mg (12 ml) a i ʻole 600 mg (24 ml) me 250 ml Sodium Chloride Injection (0,9%).

No ka pilina me ka photosensitivity o ka hoʻonāukiuki o ka infusion i hoʻomākaukau ʻia, pono ia e pale ʻia mai ke alo aku i ka mālamalama, me ka hoʻohālike, i hoʻopili ʻia me ka foil alumini. I kēia kūlana, hiki i ka hoʻonā ke mālama i kona mau waiwai no nā hola 6.

Ma hope o 2 mau hebedoma o ka lapaʻau me ka hoʻohana ʻana o nā infusions, ua huli lākou i ka lāʻau me ka hoʻohana ʻana i nā ʻano hana waha o ka hopena o ka lāʻau. Ua kuhikuhi ʻia nā kapula Berlition a i ʻole nā ​​papa i loko o kahi mālama mālama no kēlā me kēia lā o 300-600 mg a lawe ʻia ma kahi ʻōpū ʻole i ka piha holoʻokoʻa ka hapalua hola ma mua o ka ʻai, inu i ka 100-200 ml wai.

ʻO ka lōʻihi o ka infusion a me ka papa therapeutic waha, me ka hiki ke hoʻomau i kā lākou hana, ʻike ʻia e ka neʻe ʻana o ke kauka.

Ke keu

ʻO nā hōʻailona maikaʻiʻole o ka overdose moderate ka thioctic acid manifold iho ninini ke holo ana heokeo a poʻomanaʻo.

I nā pilikia koʻikoʻi, hiki ke hoʻomaopopo nā mea kūlike ʻole a i ʻole hoʻohaʻahaʻa psychomotorkulu nui nahoa, hypoglycemia (ma mua o coma), hōʻeha nui ka acid-base me ka lactic acidosiskoi hōiwi manu huakai pau ʻole organ organ, hemolisis, DIC, hana ʻana i ka hana a nā iwi ʻōiwi.

Inā kānalua ʻoe i ka hopena o nā mea momona a ka thioctic acid (no ka laʻana, i ka wā e lawe ai ma mua o 80 mg o ka mea hoʻomehana therapeutic i 1 kg o ka paona), pono ʻia e hoʻolaʻa koke ʻia ka mea maʻi a hoʻomaka koke e hoʻokō i nā hana i ʻāpono ʻia e kūhewa ai i nā mea make ʻole make.hoʻomaʻemaʻe hoʻomaʻamaʻa gastrointestinalhoʻokipa ʻenehana etc.). I ka wā e hiki mai ana, ua hōʻike ʻia kahi hōʻike hōʻailona maʻi.

Hoʻomaʻamaʻa lactic acidosis, kākele lehulehu a me nā mea e hiki ai i nā ola hōʻemi ke ola i ka maʻi ma loko o ka pā mālama pālia. ^ E Ha yM. Haka kikoʻī hoʻololi pū ʻia ʻaʻole i ʻike ʻia. Hemoperfusion, hemodialysis a me nā mea e koi ai ka kānana pono ʻole.

E hoʻokuʻu i ke ʻano a me ka ʻano

ʻO ka maʻa helu o ka Berlition 600 kahi mea kūpaʻa no ka hoʻomākaukau ʻana o kahi hopena infusion: kahi wai hoʻokaʻawale, ʻulaʻula i ka 24 ml i loko o ke kīnika aniani (25 ml) me kahi laina wāwā (ka māka keokeo) a me nā ʻōpala-melemele-ʻōmaʻomaʻo, kēlā me kēia 5 pcs. i kahi momi palani, i kahi pūpū kāleka 1 pallet.

1 ampoule he:

• mea waiwai: thioctic acid - 0.6 g,
• nā mea kōkua: ethylenediamine, wai no ka injection.

Lapaʻau lāʻau

Me ka hoʻokele intravenous o ka lāʻau, ua hōʻea ka nui o ke kaila thioctic i loko o ka plasma ma hope o 30 mau minuke. C waiwai_max like me 20 μg / ml. E hoʻomohala ʻia e ka oxidation o ke kaulahao ʻaoʻao, a me ke kolo. V_{e d} (ka helu hoʻoili) ʻo 450 ml / kg. Hoʻokomo ʻia nā Thioctic acid a me kona mau metabolites i nā aila (ke ala nui o ka excretion). ʻO ka pau hapa hapalua-ola he 25 mau minuke.

Berlition 600: nā ʻōkuhi no ka hoʻohana (ka ʻana a me nā ʻano)

Hana ʻia ʻo Berlition 600 i loko o ke ʻano o ka hoʻonā o ka infusion.

I ka hoʻomakaʻana o nā lāʻau, kuhikuhi ke lāʻau i kahi maʻa o 600 mg i kēlā me kēia lā (1 ampoule o ka hoʻokipa). Ma ke kānāwai, ʻo ka papa o ka mālamaʻana i nā wiki he 2-4, ma hope o ka mālama ʻia ʻana o ka lāʻau mālama me ka acid thioctic ma ke ʻano o nā papa i kahi maʻa kai ʻo 300-600 mg i kēlā me kēia lā. ʻO ka manawa maʻamau o ka hoʻomohala ʻana, a me ka pono no ka papa mau hou, i hoʻoholo ʻia e ke kauka.

E hoʻomākaukau i ka hopena no ka infusion, nā lōkuhi o hoʻokahi ampoule e hoʻoheheʻe ʻia ma ka 250 ml o ka paʻakai physiological. Hoʻoponopono ʻia ka hopena pahuhina, me ka lohi (ma kahi o 30 mau minuke). ʻO ka hoʻonaninani Thioctic he photosensitive, no laila ʻaʻole pono e hoʻemi ʻia ka lāʻau lapaʻau ma mua. ʻO ka hoʻonā i hoʻomākaukau ʻia e pono e pale ʻia mai ka ʻike ʻana i ka mālamalama.

Nā hopena hopena

• ka hana o ka metabolism: pohihihi - ka emi ʻana o ka glucose o ka plasma, i kekahi manawa a hiki i ka hypoglycemia (i hōʻike ʻia e nā hōʻailona e like me ka dizziness, headache, blurred vision a me ka ʻulupele nui).
• kikowaena waena a me ka pili o peripheral: lohi loa - he loli i ka ʻono, ke kāwailua ʻana o ka maʻi binocular, koikoi,
• hematopoietic ʻōnaehana: paʻakikī loa - thrombophlebitis, hemorrhagic rash, hoʻonui koko i loaʻa no ka hana platelet impaired,
• nā maʻi kūlohelohe: loa loa - urticaria, itching, wikiwiki i ka ʻili, nā hihia kaʻawale - ka pīhoihoi anaphylactic,
• kūloko kūloko: loaʻa pinepine loa - ka hoʻā ʻana i ka wahi ma ka wahi o ka hoʻonāukiuki ʻana o ka hopena infusion,
• Nā mea ʻē aʻe: paʻakikī ka hanu a me ka manaʻo kaumaha i ke poʻo (ʻike ʻia me ka hoʻokele wikiwiki o ka lāʻau a hoʻohele ma kā lākou iho).

Nā ʻōlelo kikoʻī

ʻO nā maʻi me ka maʻi maʻi e lawe nei i nā aihue hypoglycemic kūikawā e nānā mau i ko lākou koko koko koko (ʻoi aku hoʻi i ka hoʻomaka ʻana o ka maʻi me Berlition 600). Pono kēia no ka pale ʻana i ka manawa hypoglycemic state. I kekahi mau hihia, pono ke hoʻoponopono ʻia ka lāʻau ʻana i ka lā a i ʻole ka hypoglycemic drug no ka hoʻokele waha.

Me ka hoʻokele intravenous, hiki i nā hopena hypersensitivity. ʻO ka hiʻohiʻona o ka hōʻeha o ka ʻili, nausea, malaise a i ʻole nā ​​hōʻailona'ē aʻe o ka hypersensitivity he hōʻailona ia no ka hoʻopau koke ʻana i ka wai thioctic.

Hoʻopau ka waiʻona i ka hopena o Berlition 600, no laila i ka wā mālama pono ʻoe e haʻalele i ka hoʻohana ʻana i nā mea inu wai inu.

Hiki wale ke hoʻohana ʻia ka hopena o ka sodium chloride e like me ka hoʻokaʻawale ʻana no ka mea paʻa. Pono e mālama i ka hoʻonā i hoʻomākaukau ʻia i kahi wahi pōʻeleʻele, hoʻohui ʻia mai ka mālamalama e ka alumini foil. ʻOi aku ka lōʻihi o ke ola o ka hopena o ka hoʻonā ma mua o 6 mau hola.

Hoʻokomo i ka hiki ke lawe i nā kaʻa a me nā mīkini paʻakikī

ʻAʻohe ʻikepili e pili ana i ka hopena o Berlition 600 i ka hiki i ka mea maʻi e hōʻoli ai a pane koke paha i kahi kūlana, no ka mea, ʻaʻohe aʻoaʻo aʻoaʻo kūikawā i hana. I ka wā o ka mālama ʻana me ka lāʻau lapaʻau, pono e hoʻomaʻamaʻa ka mālama ʻana i ka wā e hana ai i kekahi hana e pili ana i ka piʻi nui o ke ola a me ke olakino.

Hoʻohui nūhou

Hiki i ka Berlition 600 ke hoʻohālikelike i nā ʻōmei chelate me ka hao, magnesium, calcium a me nā metala ʻē aʻe, no laila e pale pono ʻia ko lākou hoʻohana.

Hoʻonui ka Thioctic acid i ka hopena hypoglycemic o ka insulin a me ka lāʻau hypoglycemic oral, a ke hōʻemi pū ana i ka hopena therapeutic o cisplatin.

Hoʻololi nui ka Ethanol i ka hopena o Berlition 600.

No ka hoʻomākaukau ʻana i kahi hopena no ka infusion, ʻaʻole hiki iā ʻoe ke hoʻohana i nā hoʻonā o nā fructose, dextrose, glucose, Ringer, a me nā hoʻonā o ka launa pū me nā alahaka disulfide a me nā pūʻulu SH.

ʻO nā hui o Berlition 600 nā: Tiolepta, Thioctic acid-Vial, Thiogamma, Thioctacid 600 T, acid Lipoic, Alpha-lipoic acid, Thioctic acid, Lipothioxin, Berlition 300, Thioctacid BV, Espa-Lipon, Octolipen, Lipolion, Lipolion, Tololion, Tololion . ^ E Ha yM.

Berlition 600 mau loiloi

Ua loaʻa i ka lāʻau lapaʻau nā loiloi maikaʻi he nui, ʻoiai ʻaʻole ia wale nō ka hopena, akā ua hoʻomanawanui maikaʻi ʻia e nā mea maʻi. Ma muli o kāna hopena antitoxic, hoʻohana pinepine ʻia ʻo Berlition 600 i ka mālama ʻana i ka pono o ka wai. Kōkua pū ia i ka pale ʻana a me ka mālama ʻana i nā ʻōpiopio o ka maʻi diabetes, ʻoi aku ka maikaʻi ma mua o kekahi mau kikowaena.

Wahi a nā loiloi, ʻaʻole aneane like ʻole nā ​​hemahema ʻo Berlition 600, me ka ʻole o ke kumukūʻai kiʻekiʻe.

ʻ a me ke kākele

ʻO ka maʻa lā o kēlā me kēia lā he 1 mau kōpana o ka lālani Berlition® 600 mau pōmaika (e like me ka 600 mg o ka thioctic acid), i lawe ʻia i hoʻokahi manawa, ma kahi o 30 mau minuke ma mua o ka pāʻina mua.

Me ka paresthesia koʻikoʻi, hiki iā ʻoe ke hana mua i ka maʻi infusion me ka thioctic acid.

Na keiki a ʻōpio

ʻAʻole pono e lawe ʻia nā ʻōpiopio Berlition® 600 i nā keiki a me nā ʻōpio

Pono e lawe ʻia nā kapula Berlition® 600 ma kahi ʻōpū ʻole, ʻoki pono a inu i nā ʻano he nui. Hiki i ka ʻaʻai maʻalahi ke paʻakikī i ka hoʻopili ʻana. No laila, no nā poʻe maʻi e hōʻike ʻia e ka lōʻihi o ka hōʻili ʻana o ka palu, ʻoi aku ke koʻikoʻi nui e lawe ʻia ka lāʻau i ka hapalua hola ma mua o ka kakahiaka.

ʻOiai he maʻi maʻi ia i ka hihia o ka polyneuropathy diabetes, pono paha ke kau lōʻihi.

ʻO ke kumu o ka mālamaʻana i ka polyneuropathy maʻi maʻi ʻo ia ka ʻike maikaʻi loa ma luna o ka papa o ka maʻi diabetes.

E hoʻokuʻu i ke ʻano a me ka pale

Hoʻokomo ʻia nā pūlima 15 i kahi paena blister o ka film PVC (PVDH lined) a me ka alumini foil.

Hoʻoulu ʻia nā pahu kuʻuna 1 a 2 paha me nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana i nā lāʻau lapaʻau ma ka'āina a me nā ʻōlelo Lūkini i waiho ʻia i loko o kahi kīpē.

Store ma kahi wela ʻaʻole oi aku 25 ° C.

E mālama i kahi hiki ʻana i nā keiki!

Mai hoʻohana ma hope o ka lā hala.

Hoʻohui

No ka ka thioctic acid kona ʻano me kāna hoʻopili ʻana me nā mea hoʻomehana therapeutic, ʻo ia hoʻi nā mea he leona ionic (e.g. me platin Cisplatin) Ma kēia e pili ana i ka hoʻohana pono ʻana o Berlition a me ka hoʻomākaukau ʻana i ka metala i hiki ke alakaʻi i ka hoʻokaʻawale o ka hopena o ka hope.

ʻO ka hoʻokūkū pinepine ʻana o nā lāʻau e pili ana i ka ethanol e alakaʻi i ka hōʻemi i ka hopena therapeutic o Berlition.

Hoʻonui ka acid Thioctic i ka hana hypoglycemic nā lāʻau maʻi hypoglycemic waha a insulinpono ia e hoʻoponopono i ko lākou dosice dosage.

ʻAʻole hui ʻia ʻo Berlition no ka hiki ʻana i nā lāʻau lapaʻau i hoʻohana ʻia me ke kumu no ka hoʻomākaukau ʻana o ka hoʻohui infusion, ʻo ia hoʻi. hoʻonā manaʻo hoʻolāʻau a Dextrosea me nā mea hoʻonā e pane ana me nā alahaka disulfide a i ʻole nā ​​hui SH-hui.

Hiki i ka Thioctic acid ke hana i nā hōʻiliʻili sparingly me nā molika gula.

Hoʻohui Kūʻai Kūʻai

Mea Hana / Mea nona ka palapala kākau inoa inoa

BERLIN-HEMI AG (MENARINI GROUP)

ʻO Gliniker Veg 125

12489 Berlin, Kelemānia

Pākaʻi

Catalent Keleman Schorndorf GmbH, Kelemānia

ʻO ka ʻaha o ka hui e ʻae nei i nā hoʻopiʻi mai ka poʻe hoʻohana ma ka maikaʻi o nā huahana (nā huahana) ma ke aupuni o ka Repubalika o Kazakhstan:

ʻO ka hui o JSC "Berlin-Chemie AG" ma ka Repubalika o Kazakhstan

Ka helu kelepona: +7 727 2446183, 2446184, 2446185

Berlition a Heptral paha

No ka pili me nā waiwai hepatoprotective o Berlition, kahi pū o nā lāʻau lapaʻau me ka hopena restorative nā puʻuwai o ke ake, kekahi o nā mākaʻi kaulana o ia Heptral. ^ E Ha yM. ʻO kaʻoiaʻiʻo, he paʻakikī nui ka huki a like me nā hopena o kēia mau mea lapaʻau ʻelua, no ka mea ke kū nei lākou i nā ʻano lāʻau like ʻole, e komo pū ana i nā ʻano ʻano like like ʻole a ʻano like ʻole i nā ʻano hana like ʻole, eia naʻe, i ka mālama ʻana i nā pathologies ʻatikala, pinepine lākou e hoʻololi a hoʻohui pū kekahi i kekahi.

Ma muli o ka paʻakikī o ka hopena o ka Berlition ma ke kino o nā keiki, ua hoʻohana ʻia kona hoʻohana ʻana i ka maʻi pediatrics.

Nā ʻōkuhi no ka hoʻohana

Wahi a Berlition i nā kaila metabolic e hoʻoponopono ai i ka hana o ka momona o nā momona a me nā mea ʻalapine. ʻO ka mea ikaika o ka lāʻau lapaʻau ka thioctic acid. Hana ʻia ka lāʻau lapaʻau i loko o nā papa a i ke ʻano o ka manaʻo paʻa no ka hoʻomākaukau ʻana i kahi hopena no ka infusion.

Ua kuhikuhi ʻia ʻo Berlition i nā mea maʻi e hōʻeha nei i kēia ala:

• polyneuropathy, hoʻomohala i kahi o ke kua o ka maʻi mellitus a me nā maʻi alakaʻawa,
• hoʻokūkū ʻoe
• ake ka maʻi ʻūlū
• maʻi huakaʻi
• ka hoʻomohala kino.

Nā hopena hopena

Hiki ke nānā ʻia nā hopena kūpono ʻole i ka wā o ka mālama ʻana me Berlition.

ʻĀlioiaʻi

No nā palapala maʻi āpau:

• allergy, i hiki ke hōʻike iā ia iho i ka urticaria (i ka wā e hoʻohana ai i nā ʻōkuhi, hiki i nā ʻōnaehana maʻi pāpaʻi a hiki i luna anaphylaxis),
• ʻO ka emi ʻana o ke kō koko, me ka hoʻohuihui ʻia ʻo ka glucose.

No nā ʻōlelo maʻi:

• nahoa
• ʻike wua
• intrplranial hyperplasia a me ka pōkole o ka hanu (ua nānā ʻia me ka wikiwiki o ka lāʻau lapaʻau, ʻokoʻa ʻole kēia mau hopena kūpono ʻole),
• thrombophlebitis
• ʻōpū ma nā ʻili a me nā membous mucous,
• ʻāpana haʻahaʻa,
• hemorrhagic hāmanu,
• hoʻāʻo ʻia ka paila
• ka wela ana o ke kahua i ka olai ana.

1 papa i loaʻa iā 300 mg o ka thioctic acid.

E like me nā mea hoʻohui aʻe e pono ai:

• MCC
• māhoe
• waiū waiū
• silapia
• E 572,
• kahi sodium a ʻaihoe.

ʻO ka puhipuhi ka mea o kēia mau mea:

• keʻokeʻo titanium
• papaha ʻaʻai
• haniailahion,
• sodium dodecyl sulfate,
• kel miʻi E104 a me E110.

Ma 1 mau mea hoʻokūkū o ka paʻa no ka hoʻomākaukau o kahi hopena no ka infusion, 300 a 600 mg o nā mea ikaika e loaʻa paha.

E like me nā mea kōkua, aia ka ʻike i ka wai, ethylenediamine, a ʻo Berlition 300 kahi macrogol pū kekahi.

Pharmacology a me ka pharmacokinetics

Thioctic acid mea he antioxidant. Me he mea lālani o nā pākuʻi multienzyme mitochondrial, komo i loko o ka puʻuwai oxidative carboxylation o ka propanonic acid a me nā aila alpha-keto.

Hoʻemi ia i ka pae o ka glucose i ke koko a hoʻonui i ka uluʻana o ka glycogen i loko o ka ate, e kōkua ana e pale i ka pale o ka insulin. Hoʻoponopono i nā metabolism o nā lipids a me nā calcium, hoʻomaikaʻi i ka hana ate. ʻO ka hoʻohaʻahaʻa i ka pae o ka glucose, lipids a me ka cholesterol i loko o ke koko, loaʻa kahi hopena hepatoprotective.

Ke lawe ʻia ʻana i ka ʻōlelo maʻamau, e hoʻopili maikaʻi ʻia mai ka ʻōpū o ka gastrointestinal, ʻoiai i ka manawa like me ka meaʻai, emi ka nui o ka adsorption. Me ka hoʻokele intravenous, ke nānā ʻia nei ka nui o ka piʻi ʻana ma hope o 10 mau minuke, i ka manawa i lawe ʻia ai i ka waha ma hope o 40-60 mau minuke.

Ke hele nei ma o ka ate, ka metamola o ka hana ikaika, ua excreted i nā keiki.

Nā ʻōlelo a ke kūʻai a me ka waiho ʻana

Oe ke kuai i ka lāʻau lapaʻau e like me ke kauka a ka kauka.

Pono e mālama i ka hoihoi i kahi mahana ma mua o 25 mau kekona i kahi wahiʻeleʻele kahi i loaʻa ʻole ai i nā keiki.

ʻAʻole maloʻo ka lāʻau lapaʻau.

ʻO 36 mau malama ka noho o ke ola o ka pale ma luna.

Pono e mālama i nā papa ma kahi wahi i hiki ʻole ai i nā keiki, ma ke ʻano wela ʻaʻoleʻoi aʻe. ʻO 24 mau malama ka ola.

(Waiho i kou loiloi ma nā manaʻo)

* - Kahi kumukūʻai o waena ma waena o nā mea kūʻai i ka manawa o ka nānā ʻana, ʻaʻole ia he hāʻawi i ka lehulehu

Kumukūʻai Berlition, i kahi e kūʻai aku ai

Ma Lūkia, ʻo ka awelika kumukūʻai o Berlition 600 i ampoules No. 5 ka 900 rubles, a ʻo Berlition 300 ma ampoules No. 5 he 600 mau rubles. ʻO ke kumu kūʻai o Berlition 600 i nā ʻōpala No 30 mau mea e pili ana iā 1000 mau rubles. ʻO ke kumu kūʻai o Berlition 300 i nā papa Helu 30 he 300 mau rubles.

Ma Ukraine (me Kiev, Kharkov, Odessa, etc.) Berlition ma ka awelika e hiki ke kūʻai ʻia: ampoules 300 No. 5 - 280 hryvnia, ampoules 600 No. 5 - 540 hryvnia, mau pūlū 300 No 30 - 400 hryvnia, mau ʻāpana 600 No. 30 - 580 hryvnia , papa 300 No 30 - 380 hryvnias.