He aha ka meaʻoi aku ka maikaʻi simvastatin a i atorvastatin no ka cholesterol?

I ka cardiology, ua hoʻohana pinepine ʻia nā lāʻau lapaʻau mai ka papa o nā statins. Simvastatin a i Atorvastatin - ʻoi aku ka maikaʻi? Hiki ke hoʻoholo i kēia ma kahi kauka. ʻO kēia mau kālā he mea hōʻemi maoli loa i loko o ka lāʻau lapaʻau a hiki ke hoʻopakele i nā ola he nui.

Hoʻohana ʻia nā mau kālā

pale ʻana ma ka puʻuwai
ka hoʻohaʻahaʻa i ka pae o ka cholesterol maikaʻi ʻole i ke koko,
ka hoʻohiehina o ka hana.

Hiki i kēlā mau mea ke hoʻohui i kahi meaʻai, ke kumu e hoʻokau ai i nā lipid hōʻino.

Akā, ke koho pono i nā lāʻau lapaʻau me ka makaʻala loa. ʻOiai ke kūpono o nā lāʻau āpau o kēia ʻano, he nui nā contraindications a me nā hopena ʻaoʻao, no laila ke makemake nei ka poʻe maʻi e koho i kahi huahana ʻoi aku ka palekana.

No ka mea, inā koho ʻoe ma waena o Atorvastatin a i Simvastatin, he mau metala o kēlā me kēia i kekahi, e hilinaʻi ʻia ka hoʻoholo. ʻO kekahi, hiki i kahi lāʻau lapaʻau ke loaʻa kahi hopena hou aku i kahi manawa pōkole.

Akā mai kona hoʻohana ʻana i nā ʻaoʻao pili pono e haʻalele. Hiki iā lākou ke pale aku inā hoʻohana ʻoe i ka simvastatin.

He hewa paha ia i ka hoʻolālā aku i kekahi a i ʻole nā lāʻau lapaʻau ʻē aʻe me ka ʻole o ka ʻike i ke kiʻi kaukau ʻana a me ka moʻolelo hoʻomanawanui. No laila, e hoʻomaka me, pono e hoʻomaopopo i ke ʻano o ke kino o ke kanaka a hoʻomaʻi pono iā ia. Ma hope o kēia hiki ke kauoha ʻia i hoʻokahi a i ʻole kekahi lāʻau lapaʻau.

Nā hiʻohiʻona o nā lāʻau lapaʻau mai ka hui o statins

Hiki ke hoʻokaʻawale i nā lāʻau āpau o kēia ʻano i ka 2 ʻano nui:

kaʻenehana kūlohelohe (simvastatin, lovastatin, pravastatin),
kālai (Atorvastatin, Fluvastatin, Ceryistatin).

Hiki i nā lā āpau o luna ke hōʻemi i ka kolesterol maikaʻi loa e pili ana i ka 1/3. He hōʻailona maikaʻi kēia e hiki ke hoʻomaikaʻi me ka meaʻai kūikawā. Akā i kēia manawa, ʻoi aku ka pinepine o nā poʻe loea i kuhikuhi iā Rosuvastatin i nā maʻi. E komo koke ia i nā pehu o nā ate a pili pololei i ka pae o ka cholesterol i hua ai. ʻO ka hopena, ua hōʻemi ʻia ka nui o nā palaka. ʻOiai ke kuhi nei ʻo Rosuvastatin i ka lāʻau synthetic, ʻokoʻa ia ka mea i ko ka pūhui kemika mai Atorvastatin.

ʻO kahi ʻano o nā lāʻau mai ka pūʻulu statin ʻaʻole hiki iā lākou ke hoʻohana pono ʻia ma kā lākou iho, no ka mea hiki i nā lāʻau lapaʻau ke hōʻeha i nā hopena ʻaoʻao he nui, a loaʻa pū kekahi mau contraindications. Hoʻomaopopo nā loea i ka wā e hoʻohana ai i statins statins, no ka laʻana, Atorvastatin, kūlohelohe maikaʻi ʻole o nā mea ʻano like ʻole i loaʻa i ka 52% o nā mea maʻi. ʻO nā lāʻau kūlohelohe e hōʻemi loa i nā hopena liʻiliʻi. Eia nō naʻe, ʻaʻole ia i kuhikuhi ʻia no ka hoʻohana ʻana me ka ʻole o ka kūkā ʻana ma mua o ke kauka.

Pehea e hoʻohana ai iā simvastatin?

Aia ka lāʻau i ka pūʻulu o nā statins kūlohelohe. Me ka hoʻohana maʻamau, hiki iā ia ke hoʻemi i ke kiʻekiʻe o ka cholesterol maikaʻi ʻole, e pale i ka hoʻolālā ʻana o nā maʻi nui o ka puʻuwai a me nā kīʻaha koko. ʻAʻole kiʻekiʻe nā hopena o ka simvastatin. Eia naʻe, inā e hoʻohui ʻoe i ka lāʻau me kaʻai kūpono a me ka hoʻomaʻamaʻa, hiki iā ʻoe ke hoʻokō i nā hopena maikaʻi loa.

Hiki ke ʻike ʻia nā ʻōlelo aʻoaʻo a pau ke hoʻoponopono ʻia a me ka hoʻoponopono ʻia ʻana i nā kauoha no ka lāʻau. Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, pono e nīnau i ke kauka, no ka mea he nui nā hopena o ka lāʻau lapaʻau. ʻOi aku ka liʻiliʻi ma mua o Atorvastatin, akā mau pinepine a ʻike mau.

Hoʻomaopopo ʻia ʻo Simvastatin ʻaʻole wale no ka kolamu kiʻekiʻe, akā ke ʻano no ka:

puʻuwai puʻuwai a me ke kau ʻana.
ʻo ia ka pale ʻana i ka atherosclerosis a me nā pilikia vascular.

Me ka hoʻohana pono ʻana i ka lāʻau lapaʻau, ʻike kūpono ʻia ka hopena kūpono i loko o ke kolu o ka pule o ka hoʻohana. Ma hope o 1.5 mau mahina, e lilo ka hōʻemi kino o ka pōpilikia a me ka plak i nā moku.

ʻO kahi hiʻohiʻona o kēia lāʻau lapaʻau aia wale nō kahi hopena pōkole. Inā ʻaʻole ka mea maʻi ma hope o ka hiki ʻana i ka statin ke hahai i kahi papaʻai a pili pono i ka nohona kūpono, a laila ma hope o kekahi manawa manawa e lilo hou ka kiʻekiʻe o ka cholesterol. I ka wā o ka hoʻohana ʻana o Simvastatin, he mea kūpono e hāʻawi i ka wai kīʻaha iʻa e pale aku i nā hopena hopena. ʻAʻole kuhikuhi ʻia ka lāʻau lapaʻau no nā keiki ma lalo o 10 mau makahiki a me nā wahine hāpai.

Inā hewa ke hewa o Simvastatin, hiki mai paha nā hopena koʻikoʻi. He mea kūpono ia i kēia lāʻau lapaʻau, ʻokoʻa i nā statins synthetic, no ka laʻana, ʻo Atorvastatin, ka nui o nā hopena maikaʻi ʻole e like me ka liʻiliʻi. I ka hapanui pinepine, simvastatin kumu:

lie kanikela
nā pilikia ʻeha, pilikia pilikia
mea momona.

I nā hihia lōkahi, hiki i kēia:

huakaʻi renal function,
nā maʻi kūlohelohe, no ka laʻana, ka ʻūwū o ke kino,
nā pilikia ʻike
nā wahī o ke ʻōnaehana.

ʻO nā wahine hāpai a me nā keiki ma lalo o 10 mau makahiki o ka poʻe i hoʻohālikelike ʻia a contraindicated. Aia a hiki i ka 18 mau makahiki o Simvastatin i ʻōlelo kū ia inā he ikaika ikaika.

Nā hōʻailona a me nā contraindications no ka hoʻohana ʻana o atorvastatin

He ikaika aku kēia statin. Ua hoʻohālikelike ʻia no ka cholesterol kiʻekiʻe, nā maʻi o ka ʻōnaehana cardiovascular, ka maʻi diabetes mellitus a me ka mea he prophylactic e hōʻemi i ka hopena o ka hōʻeha o ka naʻau a me nā hōʻeha.

Hoʻohui kekahi hopena ikaika me ka ʻoi aku ka nui o nā hopena ʻaoʻao. Kū pinepine pinepine lākou i nā poʻe maʻi e hōʻole i ka dosage a loaʻa paha ka contraindications i ka hoʻohana ʻana i ka lāʻau. ʻAʻole hiki iā ʻoe ke hoʻohana i ka atorvastatin:

i ka wā hāpai
me nā puʻuwai koʻikoʻi
ka hele ana o nā waiʻona,
mahope iho o ka hana nui ʻana.

Me ka hoʻohana pono ʻole o Atorvastatin, hiki i nā hopena he nui ke kulu, mai ka ʻeha a hiki i nā hōʻeha nui o ka ʻōnaehana. Hoʻomaʻamaʻa pinepine nā poʻe maʻi e lawe nei i kēia lāʻau lapaʻau mai kahi hōʻino o ka digestive tract, ʻeha a me ka pohā.

ʻO wai ke ʻano ʻoi aku ka maikaʻi?

ʻO ka kauka hele wale nō e pane pololei i ka nīnau no ka mea e pono ai ka lāʻau a pau ma hope o ka hoʻopaʻa ʻana i ka maʻi o ka mea maʻi a me nā kaʻina hana āpau e pono ai. Akā inā ʻoe e noʻonoʻo i ka mea hana, ke kūleʻa nei ka ʻokoʻa i ka mea ʻoi aku ka ikaika o Atorvastatin, a me ia e hiki wikiwiki iā ʻoe ke loaʻa nā hopena maikaʻi i ka mālama ʻana.

ʻO Simvastatin, he statin kūlohelohe ka mea e hōʻemi i nā hopena liʻiliʻi. Ke hoʻohana ʻia, ʻaʻohe nui o ka hōʻuluʻulu ʻana o ka kila kila, ka mea i manaʻo ʻia he mea ʻona.

Hōʻike nā hōʻike i kēia mau lāʻau kūʻokoʻa i kēlā me kēia i ka Simvastatin e hōʻike ana i ka hopena o ka hōʻemi ʻana i ka kolesterol kino kino ma o 20%, aʻo Atorvastatin me ka lōʻihi o ka hoʻohana ʻana e hoʻemi i ka pae o nā lipid weliweli ma kahi aneane 50%. Inā pono i ka mea maʻi e hoʻomaʻamaʻa hou loa, ʻoi aku ke kau ʻoi ma ka atorvastatin. No nā mea pale a me ka hele mai o nā hopena alerine i nā mea hoʻohui o nā statins syntical, e kuhikuhi ʻia paha ʻo Simvastatin.

ʻO nā hiʻohiʻona pharmacological ākea o nā statins

Aia nā statins a pau i keʻano o nā lāʻau lapaʻau e pili pono ana i ka lipid metabolism i ke kino o ke kanaka. I ka hoʻonaninani ʻenehana, hoʻomehana a me ka ʻoihana kemana o ka lāʻau, ua kuhikuhi ʻia me ka code C10AA a ua helu ʻia i ka poʻe HMG-CoA reductase inhibitors. Ke hōʻike nei i ka hana o kēia enme, hoʻonāukiuki lākou i ka synt synt o ke kolamu, hoʻēmi i ka nui o kona serum. Hiki i kēia hana no statins ke hiki aku i ka ʻike ʻia ʻana o nā mea hoʻopiʻi haʻahaʻa haʻahaʻa ma ke koko.

Hiki i kēlā mau hopena ke hōʻemi nui loa i ka helu o ka hoʻomohala ʻana i nā mea hoʻohālike atherosclerotic. Eia kekahi, ke pale aku nei i nā lāʻau i kāna hōʻeha ʻana. ʻOiai me kona hiki ʻana, he hopena maikaʻi nā statins: hoʻopaʻa lākou i ka endothelium ma luna o kahi pākeke atherosclerotic, a no laila e hoʻemi nui ʻia ka hopena o ka thrombosis coronary, e hana ana i ka ʻokoʻa ʻokoʻa ma mua o nā mea hana antiplatelet. Eia kekahi, ʻo ka hoʻohana pū ʻana o kēia mau kālā hiki iā ʻoe ke hōʻemi hou aʻe i ka hōʻeha ʻana o ka puʻuwai puʻuwai. No laila, ua hoʻāpono loa ʻia ke kumukūʻai no nā statins.

ʻO nā hiʻohiʻona o ka helu ʻana o nā statins

Nui nā ala ʻē aʻe i ka hoʻokaʻawale ʻana i nā lāʻau i nā papa. Hiki iā lākou ke noʻonoʻo mai ka manaʻo o nā hiʻohiʻona synthes. Eia kekahi, ʻo ka mea e mālama ai i nā statins ʻē aʻe i makemake i nā ʻōhua like ʻole, e noʻonoʻo pono e hoʻolauna i ka hoʻonohonoho ʻana ma nā ʻano hana i ʻōlelo ʻia. He ʻano ʻōpiopio penei:

ʻO koʻu hanauna: "Simvastatin", "Pravastatin", "Lovastatin".
ʻEle II hanauna: "Fluvastatin."
III hanauna: "Cerivastatin", "Atorvastatin".
IV hanauna: "Pitavastatin", "Rosuvastatin."

Hoʻokaʻawale ʻia nā statins a pau i loko o nā mea kila, synthesized mai nā mea maka, a me nā mea kūlohelohe. ʻO ka hope aʻe ʻo Lovastatin, Pravastatin, a me Simvastatin. ʻO nā lāʻau āpau a pau he synthetic: Fluvastatin, Atorvastatin, Rosuvastatin a me Pitavastatin.

Ka helu ʻana o nā statins ma ke ʻano

He kūpono ke hoʻokaʻawale i nā lāʻau lapaʻau āpau, me nā stins o ka hanauna hope loa, i loko o nā haʻahaʻa haʻahaʻa (a i ka 8 mg), ka nui (dosis - 10-40 mg) a me nā haʻahaʻa kiʻekiʻe (40-80 mg). Ma kahi kikoʻī:

nā lāʻau lapaʻau nui (Atorvastatin, Lovastatin, Fluvastatin),
nā lāʻau lapaʻau me nā lohi ("Simvastatin", "Pravastatin", "Rosuvastatin"),
nā lāʻau lapaʻau haʻahaʻa ("Pitavastatin").

Hōʻike kēia ʻano i nā pono o ke kuhikuhi ʻana i nā lāʻau lapaʻau a me kā lākou therapeutic ākea. I ka lāʻau, ʻike ka hopena o nā lāʻau lapaʻau kiʻekiʻe i ka nui, ʻoiai ua hoʻomanawanui maikaʻi ʻia. ʻO nā lāʻau lapaʻau liʻiliʻi loa, koe wale nō no "Rosuvastatin", e ʻoluʻolu i ke kāʻei kiʻekiʻe, akā maikaʻi ka hopena.

Ka helu 'statlelo -ʻo Mediin-dosis "Rosuvastatin", inā pono, e hiki ke kahakaha ʻia ma kahi ʻai kiʻekiʻe (80 mg), ʻoiai no ka hōʻemi ʻana i ka nui o ka kolamu a me kāna haʻahaʻa haʻahaʻa haʻahaʻa, ʻoiai ʻaʻole pono ia. "Pitavastatin" pono ia i ka koho ʻana i nā helu liʻiliʻi, ʻo ia ke kumu o nā pilikia o ka hoʻopiʻi maikaʻi ʻana i nā manawa he mau manawa ma mua o nā papa o nā mele.

Ka mōʻaukala o ka hoʻomohala ʻana a me ka hoʻokō ʻana i nā statins

Ua kāwili ʻia ka mōʻaukala o nā statins. I ka mua, ua hoʻokaʻawale ʻia kā lākou hoʻomohala ma muli o ka naʻaupō o ka metabolism cholesterol a me ka hopena o ka hoʻomohala ʻana i ka atherosclerosis hilinaʻi i nā pae lipid koko. Eia kekahi, ua hoʻokomo koke ʻia nā māka gopocholesterolemic me ka pahuhopu o ka hoʻopaʻa ʻana i ka microflora i loko o nā puhā o nā fungi i manaʻo ʻia e hana i nā penicillins maʻemaʻe. ʻO ka loaʻa ʻana o ka hana anticholesterol mai kekahi mau mea i hana ʻia e ka huaʻai, a ua hiki iā ia ke aʻo i nā statins.

ʻO ka statin mua ka compactin, ʻaʻole i hoʻokomo ʻia i ka hana kulekele ma muli o nā ʻano kuhi hewa ʻole e pili ana i kona mau hopena. Ua hoʻokaʻawale ʻia mai kahi moʻomeheu Penicillium cetrinium. A laila, hōʻiliʻili ʻia ʻo Monacolin K, i hala i ka mahina ʻo Pepeluali 1979, mai ka moʻomeheu ruber Monascus. I Iune Iune 79, ua ʻike ʻia ʻo Mevinolin, i kapa ʻia ʻo Lovastatin. Ua hoʻohana ʻia kēia lāʻau lapaʻau i ka haukapila, ma hope o kahi o nā statins o ka hanauna hope i hoʻokaʻawale a hoʻokaʻawale paha.

Nui nā manaʻo kūʻē kūʻē i ka hoʻomohala ʻana i nā statins, ma hope iho ua hoʻoholo ʻia e hana i nā hōʻike lāʻau lapaʻau nui. I kēia manawa, ua lilo ka noiʻi nui loa a me ka hoʻohana ʻia a lilo ʻo Scandinavian Simvastatin Survival Study. ʻO kāna inoa pōkole ʻo "4S". Hōʻike piha loa ia i ka hiki ke hoʻomohala ʻana i nā maʻi carcinogenic pili i ka lawe ʻana i nā lāʻau lapaʻau, a hōʻoia i ko lākou hoʻohana ʻana e hoʻonui nui i ka mana o ke ola a hoʻēmi i ka piʻi o nā pathologies coronary.

ʻO nā makemake i nā statins

Me ka hoʻomaka mua o ka kolamu nui o 7.4 mmol / L, therapy statin a hōʻea i kahi pae o 5.4 mmol / L nui e hoʻemi i ka hōʻeha o kahi hanana cardiovascular maʻi ma kahi o 40% i nā makahiki 5 e hiki mai ana. I loko o kekahi mau haʻawina hou, ua hōʻike ʻia ka emi ʻana o ka kolamu ka nui o ka 1 mmol / l ma kahi hapalima he hōʻemi i ka hopena o ka trombosis coronary a, ma ia mea, hōʻehaʻeha a hōʻeha paha.

Ke noʻonoʻo nei i nā statins, no a me ke ʻano o nā loea a me nā poʻe maʻi e ʻōlelo ai, hiki i kekahi ke hoʻomaopopo i kēia mau ʻoiaʻiʻo iho: hiki iā ʻoe ke kuhikuhi i ka lāʻau lapaʻau i kona makahiki he 40 a ʻoi aku ka nui, a me ka hōʻemi ʻana i nā hōʻehaʻeha o ka maʻi puʻuwai he hana hoʻomau no ka lōʻihi o ke ola ʻana. A no ke kumu kūpono ke kumu kūʻai o nā statins, hiki ke hopu ʻia kēia mau lāʻau i hōʻike ʻia me ka ʻole o ka hoʻolana ʻana i kāu kālā ponoʻī. ʻO kaʻoiaʻiʻo, ʻoi aku ka ʻoi aku o ka statins hou o nā statins, ʻoiai ʻo ia ʻo "Rosuvastatin", ma ke kānāwai, he kūpono loa ia no ka mea maʻi. Aʻo kona ala momona loa ʻo ka lāʻau Mertenil.

Hoʻohālikelike ʻano: pros a me cons

Ke aʻo nei i nā statins, he mea maʻalahi loa ia e ʻōlelo ai no ke kūʻē ʻana iā lākou. ʻO nā hoʻopaʻapaʻa no nā hiʻohiʻona o kā lākou hopena therapeutic: hoʻohaʻahaʻa i ka kolamu koko a me kāna haʻahaʻa haʻahaʻa haʻahaʻa, pale i nā pilikia o nā hanana koʻikoʻi a kōkua i ka mālama ʻana iā lākou. Eia naʻe, nā lāʻau lapaʻau e like me nā statins he mau contraindications. Aia kekahi mau ʻaoʻao e hoʻopiʻi i nā hoʻopaʻapaʻa e kūʻē i ka hoʻohana ʻana.

Me ka therapy statin, aia kahi pilikia o ka myopathy. Hoʻoulu paha ia i ka pale ʻana i ke kāpili ʻana o ka cholesterol, kahi e pono ai e nā ʻuhane. He haʻahaʻa loa ka lōʻihi o kēia hopena, ʻoiai ke hoʻonui nei a i ka wā i lawe pū ʻia me nā lāʻau lapaʻau e hoʻopau ʻia. Aia nō kekahi hopena hopohopo i ka hoʻomoʻa ʻana i ka maʻi palupalu, ʻoiai paha ka hopena o kēlā maʻi, e like me nā hōʻike hou ʻana i hōʻike ʻia. I ka manawa like, ua hoʻāʻo ʻia ka mea maʻi ma oncological e nā mea ʻē aʻe. No laila, no nā lāʻau lapaʻau o ka pūʻulu "statins", pono nā pāpā i pāpā ʻia i ka hoʻohana ʻana i kēia mau lāʻau me nā lawena ʻē aʻe e kōkua i ka hoʻēmi ʻana i ka hoʻohuihui ʻana i nā momona i nā pā.

ʻO ke kumukūʻai o ka hanauna hou o nā statins

ʻO nā statinsʻilima hope loa he mau kumukūʻai like ʻole, ʻoiai ʻo ia mau hopena i kūpono ke kumukūʻai. ʻO kekahi nīnau wale nō ke hiki ke loaʻa i nā hopena o kā lākou hana me ka hoʻohana ʻana i nā mea kākau haʻahaʻa o nā haʻahaʻa o nā hanauna i hala. Ma keʻano kūikawā, ke kumukūʻai o ka statin maʻamau maʻamau o ka hanauna 4 "Rosuvastatin" e pili ana i kēia:

600 mau rubles no ka papa 40 mg,
400-450 pākaha papa o 20 mg,
300-350 ma nā papa 10 mg,
200 mau rubles no ka 5 mg.

Aia ka papa i ka 30 papa, he lawa no ka malama o kēlā me kēia malama, aʻo ka mālama ʻana i hoʻokahi malama me Pitavastatin e like me nā kumukūʻai e like me kēia:

Nā kumukūʻai 1 mg pili ma kahi o 700-750 rubles,
2 mg papa - like 1000 rubles,
4 papa papa - he 1,500 rubles.

ʻO ka koho ma waena o Pitavastin a me Rosuvastatin e kau nei i nā pae ʻehā: ke kumu kūʻai, helu hōʻemi i ka lipoproteins low haʻahaʻa, hoʻopau i ka hoʻonui ʻana i nā lipoproteins kiʻekiʻe, a me ka palekana. Wahi a ke ʻano o ka hoʻohaʻahaʻa ʻana i ka cholesterol a me ka hoʻonui ʻana i ka HDL, a me ke kumukūʻai, "Rosuvastatin" ka mea maikaʻi loa, ʻoiai ʻo "Pitavastatin" ʻo ia ka ʻoi aku ʻoi loa.

ʻO kahiʻoi aku ʻelua ma mua o ka hoʻohālikelike ʻana iā Rosuvastatin. Eia nō naʻe, aia kahi kūpono o ka hoʻohana ʻana i nā statins eʻoi aku.ʻO ka uku kūʻai maikaʻi loa ma mua o Simvastatin. I kēia manawa ua hoʻololiʻo ia iā Atorvastatin, kahi i hoʻohuli maoli ʻia e Rosuvastatin (pono e hāʻule ka waiwai). A inā he kumu kūpono ʻole nā kumukūʻai no nā statins o nā hanauna hou loa, a laila pono e noʻonoʻo pono i ka hiki ʻana o ke ʻano maʻi me Atorvastatin a i Simvastatin. Ma ke ala, ua lawe ʻia ka hapa nui o nā haʻawina me Atorvastatin.

ʻO ka hihia no ka hoʻohana ʻana i nā statins e nā poʻe kahiko

Ua hoʻokuʻu mua nā kauka i nā loiloi e kākau i nā statins no nā poʻe maʻi ma mua o 75 mau makahiki o ko lākou mau makahiki. O ke kumu:

ka lawe ana i kekahi mau mea lapaau o nā papa ʻē aʻe,
ka makemake ʻole e hoʻohui i kekahi ʻano o nā lāʻau lapaʻau,
nele a ʻohi haʻahaʻa haʻahaʻa,
hiki i ka mea maʻi ke kūʻai a hoʻohana a hoʻohana i nā statins ma muli o ka ʻike ʻole o kā lākou hopena.

Ua hōʻike kekahi mau haʻawina me Simvastatin, Pravastatin, a me Atorvastatin i kahi nui o ka hoʻemi ʻana i ka make ma ka poʻe maʻi ma mua o 75 mau makahiki. Eia kekahi, ʻo ka emi ʻana o nā helu make ma mua o ka maʻi ma mua o nā maʻi i nā makahiki 55-65 a me 65-75 mau makahiki. No laila, no nā lāʻau lapaʻau o kēia ʻano (statins), nā loiloi o nā loea e hōʻoia pololei ʻole i hoʻokahi mea.

Hiki i kēia mau lāʻau lapaʻau ke lawe ʻia a i ka wā ʻōpio, ʻoiai ʻoiai inā hele mai nā maʻi vascular ma mua. A me nā poʻe maʻi e ʻike pono loa i ka hōʻemi o ka make o ko lākou make mai ka myocardial infarction a i ʻole ka maʻi ʻaʻa e pono e hoʻomaopopo e inā maikaʻi ka lāʻau a palekana, no laila he mea maoli e lawe. Eia nō naʻe, ua lilo i mea mālama loea statin a laila e hoʻomau ʻia nō naʻe.

ʻO ka wehewehe ʻana i nā loiloi mai nā statins o nā hanauna i hala

Pau ka loiloi hoʻomanawanui i ka nānā ʻana i ka maikaʻi o kahi statin generic maʻamau, ʻaʻole i hōʻike ʻia, no ka mea, ʻaʻole lākou e manaʻo i kekahi mau loli koʻikoʻi mai ka lawe ʻana i nā lāʻau lapaʻau. ʻO ka hoʻonui ʻana i ka ʻike lipid o ke koko ʻaʻole i hōʻike pono iā ia iho i ke olakino a ʻaʻohe i nā hōʻailona o waho. ʻIke ʻia ia ma ka profile lipid wale nō. No laila, ke nānā aku nei i statin, he mea kūpono ke alakaʻi e nā loiloi e nā loea. Eia kekahi, e pili ana i nā lāʻau lapaʻau i ka mea e hoʻomohala nei ka pitavastatin, ʻaʻole hiki i nā poʻe loea.

Ma ka hana lapaʻau i loko o CIS, ʻaʻole i hoʻohana ʻia ʻo Pitavastatin ma muli o kona kumukūʻai nui loa a ma muli o ka hiki ʻana o Rosuvastatin a me kāna mau akono. ʻO ka mākaukau me Rosuvastatin, i hōʻike ʻia ma luna, he hana wikiwiki: ka paʻakū lipid ma nā mahina 1-2 mau. ʻO ka manawa Atorvastatin hoʻokahi a me ka hapa manawa ka lōʻihi. ʻO nā mea koa, ʻoi aku ka palekana o ka "Rosuvastatin", no ka mea ua hoʻohālikelike ʻia lākou e ʻelua mau wahi o ka cytochrome. I kēia manawa, ua ʻike ʻia kēia ʻike, mai ka loiloi loiloi, e hana koʻikoʻi i ke koho o statin i nā kūlana kulekele kūikawā.

ʻO nā ʻike ākea ma nā statins o nā hanauna i hala

ʻO nā lāʻau lapaʻau ʻo Pitavastatin a me Rosuvastatin ka mea hou loa i waena o nā ʻelele o ka papa o nā statins, kahi i hōʻiliʻili ʻia ai kahi kumu hōʻike nui. Hoʻohā like kā lākou mau hopena me nā Atorvastatin, akā aia nā ʻokoʻa. "Pitavastatin" a me "Rosuvastatin" e ʻae e hōʻea i nā kiʻekiʻe o ka cholesterol, a me ka lipoproteins haʻahaʻa haʻahaʻa ma kahi lalo haʻahaʻa o ke "Atorvastatin".

Ma kahi o nā pono i luna o nā statins o nā hanauna i hala, he mea nui hoʻi kekahi ʻaoʻao. Loaʻa: i ka wā mālama me Pitavastatin a me Rosuvastatin, kahi hana wikiwiki wikiwiki loa o ka lipids koko a me ka wehe ʻana o ka homocysteinemia. Ua koʻikoʻi kēia i loko o ka hihia o ka pathology lolo koʻikoʻi a ma ka maʻi ischemic maʻi hoʻonāukiuki ʻia e ka corherary atherosclerosis. ʻOi aku ka palekana o ka hoʻohana ʻana i nā statins e ʻoi aku ma mua o ka cardioform o acetylsalicylic acid. Eia naʻe, eia ka hele ʻana o contraindications e pāpā aku i kā lākou hoʻohana ʻana e kekahi mau contingent o nā maʻi (e ʻike i nā contraindications maʻamau).

Nā lāʻau lapaʻau lāʻau

Loaʻa nā lāʻau lapaʻau e loaʻa ana iā Rosuvastatin ma lalo o nā inoa kālepa inoa nei: Akorta, Rosistark, Rosucard, Rosart, Mertenil, Rosulip, Roxera, Rustor, Tevastor. ʻO kēia mau lāʻau āpau he generic "Crestor", kahi i lilo ka rosuvastatin mua. ʻO ka lāʻau lapaʻau, i loko o ka huahana ikaika he pitavastatin, hoʻopaʻa inoa ʻia ʻo "Livalo". ʻO Pitavas a me Pivasta kona mau mea kanu. ʻAʻole lākou i hoʻokau ma CIS, ʻoiai ua hoʻopaʻa ʻia i loko i ka pharmacopeia.

E like me nā hopena o nā papa lāʻau a me ka loiloi o ka hopena o kā lākou lawelawe, ua hoʻāpono ʻia ka hoʻohana ʻana o nā statins e hoʻokūkū i ka pāpaʻi atherosclerotic a pale i kona wāwahi. Hoʻohana ʻia lākou e hōʻemi i ka nui o ka atherosclerosis, e hoʻopiʻi i ka ʻōlelo lipid o ka serum koko. I ka hopena, pono ke ʻano o kēia papa o nā lāʻau lapaʻau ma ka cardiology. A ua paʻa pono nā statins kiʻekiʻe o ka hanauna hou i ka pale ʻana i ka thrombosis coronary fatal.

Nā hōʻailona no nā stins

Aia nā statins i ka hui o nā lāʻau lipid-haʻahaʻa.

ʻO ka hōʻailona nui no ka mea i koho ʻia ka hoʻoponopono ʻana o ka hana lipid metabolism.

ʻO kahi papa hopena mua o ka lāʻau lapaʻau e hiki ai iā ʻoe ke hoʻomaʻamaʻa i ka momona metabolism a hoʻopau i nā hōʻailona āpau o ka hōʻemi kino o ka atherosclerotic.

Ma ka hoʻomaʻamaʻa lāʻau, ua pono ke hoʻohana ʻia o statins no:

ka hana pū ʻana me ka ʻaina o ka hana kino dosed o nā maʻi me nā kiʻekiʻe o ka lipher atherogenic i ke koko,
e hoʻonui i ke kiʻekiʻe o nā lipoproteins antiatherogenic,
no ka mea i ka poʻe maʻi ʻaʻole ʻike i nā hoʻopiʻi kumumanao o ka pathology pathology, akā aia nō i ka make (ʻo ka luhi o nā mōʻīlau hoʻoilina, nā hoka, nā maʻi maʻi hypertensive, diabetes mellitus),
ka mālama ʻia ʻana o ka maʻi naʻau coronary, ka mea i hōʻike ʻia e ka pectoris angina,
ka pale ʻana o nā pilikia ma ka maʻi cardiovascular,
ka mālama ʻia ʻana o nā maʻi hoʻohemo i pili me nā maʻi dyslipidemic.
ka mālamaʻana i ka metabolic syndrome.

ʻO ke kuhi o nā noi o nā lāʻau ʻelua ke mālama i ka lipid metabolism.

ʻO ke koho e makemake ana i ka Atorvastatin a i ʻole Simvastatin, ka mea i hoʻopili ʻia o ia ʻano mea like, e hilinaʻi ʻia i nā mea he nui. No ka laʻana, ʻoi aku ka maikaʻi o ka statin i mea e pale aku ai ka lua, i ka lua no ka mālama ʻana.

Eia kekahi, pili ka pono i ke koho ʻana o nā contraindications a me nā mea e kau ʻia ai ka hoʻohana ʻana.

Ke aʻo nei i kahi lāʻau lapaʻau kūikawā, ke hoʻohuli ʻole ʻia i ke kūlana kulekele, kahi hewa ʻole ʻole. Pono ke koi ʻana i nā ʻike piha o ke kūlana olakino o ka mea maʻi.

ʻO nā hiʻohiʻona maʻamau o nā statins

Wahi a ka helu honua, ua mahele ʻia nā statins i nā lāʻau semisynthetic mua synthesized a, ma hope aku, synthetic. Hoʻohana 'iaʻi nā hanauna o nā lālani.

ʻO Simvastatin kahi statin semi-synthetic o ka hanauna mua. Atorvastatin - i ke ʻano hana o ka hanauna 4. Hōʻike ka huakaʻi ʻehā o nā statins i ka maikaʻi kiʻekiʻe a me kahi kikoʻī liʻiliʻi o nā hopena pili.

ʻO ka maʻi Hypolipidemic hiki iā ia ke hōʻemi i ka neʻe o ka lipids atherogenic ma o ka liʻiliʻi ʻekolu.

I ka hui pū ʻana me kahi meaʻai kaulike a me ka hana kino dosed, hiki i ka lāʻau ke hoʻōla i ka hana lipid metabolism.

He nui nā mea maʻi e noʻonoʻo nei i ka mea o ke ʻokoʻa ma waena o ka lāʻau Simvastatin a me ka mea hou aku ʻo Rosuvastatin (ka inoa kālepa - Cross). I kēia lā, makemake nā poʻe loea i ka lāʻau Rosuvastatin. ʻO ka mea hope loa he huahana lāʻau lapaʻau hou. Ke koho nei i ka simvastatin a i ka rosuvastatin kahi ʻoi aku ka maikaʻi, hāʻawi ʻia ka makemake i ka rosuvastatin. ʻO ka hana o kāna hana he wikiwiki ka wikiwiki o nā molekui ikaika i ka hepatocytes, kahi ia e loaʻa ai ka hopena ma ke kiʻekiʻe o ka hōʻailona synthesized. A ke hopena, hōʻemi ʻia ka ʻike ʻana o ka cholesterol endogenous a luku ʻia nā ʻano atherosclerotic i hoʻokumu ʻia.

He mea nui ia e hoʻomaopopo he pāpā ʻia ka hoʻohana ʻana i nā statins me ka ʻole o ke kauka a ke kauka. ʻO kēia pāpā paʻa loa e pili me nā ʻano o contraindications a me nā palena.

Ma mua o ka hapalua o nā mea maʻi e lawe i nā statins i waiho i nā loiloi unflattering e pili ana i ka lāʻau. Eia naʻe, ʻo ka hapa nui o nā hopena ʻaʻole ia kahi hōʻike no ka haʻalele o ka lāʻau.

Ma keʻano holoʻokoʻa, hoʻokaʻawale maikaʻi nā statins a loaʻa i kahi hopena pono e pili ana i ka lipid metabolism.

Nā ʻōkuhi no ka hoʻohana ʻana i ka simvastatin

ʻO ka lāʻau lapaʻau he māla semi-synthetic o ka hanauna mua o nā statins. Ke kōkua nei kāna kaukau maʻamau i ka hōʻemi nui ʻana i ka pae o ka cholesterol atherogen, e pale ai i ka hiki ʻana mai o nā maʻi maʻi āpau.

Eia naʻe, ua haʻahaʻa ka hopena o Simvastatin me nā hanauna ʻē aʻe. Eia naʻe, me ka hōʻoluʻolu a me ka hōʻeha o ka atherosclerosis a me ka hoʻohui pū ʻana me ka meaʻai a me ke kaumaha, ua loaʻa i kēia lāʻau lapaʻau ka pono o ka mālama ʻana i ka mea maʻi.

Wahi a nā ʻōlelo kauoha no ka komo ʻana, e manaʻo ʻia ka huahana no ka hoʻohana ʻana i loko. Loaʻa ka lāʻau lapaʻau i kahi palapala papa.

Hoʻomaopopo ʻia e lawe i kahi pākahi hoʻokahi o ka lāʻau i ke ahiahi, me ka ʻaole ʻole ʻana i ka kūʻokoʻa o ka pūpū.

Hoʻoholo ʻia ka ʻona lā i kēlā me kēia lā. Ma mua o ka hoʻomaka ʻana i ka maʻi me ka simvastatin, ʻoi aku e loaʻa i ka hoʻoponopono ʻana loa o ka lipid metabolism me ka hoʻohana ʻana i ka hana hoʻoikaika kino a me ka meaʻai kūpono. Hiki i ke lāʻau lapaʻau ke wehewehe wale i ka pau ʻole o ka hopena o ka meaʻai a me ke kaumaha.

Hoʻoholo ʻia ka lōʻihi o ke papa a me ka loaʻa o ka simvastatin e ke kauka o ka mea maʻi, i ka ʻike ʻana i ka pae hoʻomaka o ka cholesterol a me nā ʻano o ke kino.
Hoʻololi ʻia ka ʻōhala o kēlā me kēia lā i ka 5 a 80 milligrams.
Hiki ke hoʻoponopono ʻia i ka lāʻau ʻōlelo ma mua o hoʻokahi mahina ma hope o ka hoʻomaka ʻana o ka mālama ʻana.

Hoʻole ʻia i ka hoʻololi kūʻokoʻa a hoʻoulu i ka lāʻau lapaʻau.

ʻO ka alakaʻi kūpono ʻana i ka lāʻau lapaʻau e hōʻoia i ka hoʻomaka ʻana o kahi hopena therapeutic ma ka hopena o ka mahina mua o ka hoʻomaʻamaʻa.

Ma hope o hoʻokahi mahina a me ka hapa, e hoʻomaʻamaʻa ka pae o ka cholesterol atherogenic.

ʻAʻohe o statins i kahi hopena cumulative. Mālama wale nō ka lāʻau lapaʻau i ka wā o kāna hana hoʻomalu.

Inā ʻaʻole ʻoe e hahai i kahi ola olakino ma hope o ka hoʻokuʻu ʻana i ka lāʻau lapaʻau, ma hope o kekahi manawa, hiki ke piʻi hou ka ʻaila o ka lua o ka endogenous.

Nā ʻōkuhi no ka hoʻohana ʻana i atorvastatin

Hiki i kēia lāʻau lapa ke ʻano hou me ka wikiwiki. Pono e hoʻohālikelike ʻia no ke kolamu kiʻekiʻe, nā maʻi naʻau coronary, mellitus maʻi maʻi koʻikoʻi a no ka mālama ʻana i nā catastrophes mahele ponoʻī.

Loaʻa i ka Atorvastatin ka loiloi kiʻekiʻe loa mai nā kauka olakino e pili ana i kāna hana koʻikoʻi.

ʻO Atorvastatin kahi lāʻau lapaʻau i manaʻo ʻia no ka hoʻoponopono waha. Pēlā nō e like me ke kūlana me Simvastatin, ʻo Atorvastatin e pono ke kuhikuhi wale ma hope o ka loaʻa ʻole o ka lāʻau lapaʻau ʻole.

Koho ʻia ka lā helu o kēlā me kēia lā i ka ʻano o ka nui o ka maʻi a me nā ʻano pilikino o ka mea maʻi.
ʻO ka pilina mua o ka lāʻau lapaʻau he 10 mg. Hoʻopili ʻia ka hoʻoponopono ʻana ma hope o hoʻokahi mahina mai ka hoʻomaka ʻana o ka mālama ʻana.
ʻO ka hoʻohana pinepineʻana i ka lāʻau lapaʻau e hāʻawi i ka emi ʻana o ka neʻe o ka lipher atherogenic ma mua o ka hapalua.

ʻO kahi hiʻohiʻona o ka lāʻau lapaʻau he hopena hōʻoluʻolu i nā nephrons. Ma kēia pili, ua hōʻike ʻia no ka hoʻohana ʻana e nā mea maʻi e loaʻa ana i ka hiki ʻole o ka pilikia ʻoi. ʻO ka nui loa o ka lāʻau lapaʻau ka 80 mg. Hōʻike ʻia ʻo Atorvastatin i nā keiki i kahi pane iʻoi aku ma mua o 20 mg.
Ma mua o ka lawe ʻia ʻana, pono e pākuʻi i nā ʻohi enema.

He mea nui ia i ka wā mālama e loiloi i ka hana a ka enzymatic o ka pepelu.

Nā hopena ʻaoʻao a me nā contraindications no nā statins

ʻO kahi hiʻohiʻona o ka hoʻohana ʻana o Atorvastatin a me Simvastatin ka mālama mau ʻana i nā lālā nui a me nā ʻōnaehana. He hopena koʻikoʻi ka lāʻau lapaʻau i nā hana momona o ka momona. Ma kēia hono e pili ana i ka mālama ʻana i ka homeostasis o ke kino.

Ua haʻi aku nā statins i nā hana pharmacological no laila, ua palena kā lākou hoʻohana i kekahi mau kūlana physiological a me ka pathological.

ʻO nā ʻano e pili ana i kēia mau contraindications i ka hoʻohana ʻana o statins:

He mōʻaukala o ka hypersensitivity i nā lāʻau i koho ʻia.
Ka lule a lactose. ʻO ka hoʻonohonohoʻana o nā mākaukau me ka lactose.
Nā ʻano āpau o ka myopathy.
ʻO nā maʻi o ka ate i kahi hana ikaika.
Nā makahiki o nā keiki a hiki i 10 mau makahiki.
Alikaihue
ʻO nā maʻi ʻeha hope loa.
ʻO ka hopena kiʻekiʻe loa o ka hana renal ka hoʻomaʻamaʻa.
Therapy me nā immunosuppressants.
Hoʻolālā no ka hana nui.
Ua papa ʻia ʻo ka lawe ʻana i nā kaʻa a me nā ʻenehana e koi ana i ka ʻike kiʻekiʻe a me ka nānā ʻana i ka wā e lawe ana i nā statins.
Kahawai Loaʻa ka lāʻau lapaʻau i ka hopena teratogenic ikaika. I kēia pili, ua pāpā ʻia no ka hoʻohana ʻana i nā wahine hāpai.
Hoʻokaumana.

Ke lawe nei i nā statins semi-synthetic, pono e haʻalele i nā kīʻaha citrus, me ko lākou hui pū kekahi e hoʻonui i ka hopena o ka hopena ʻaoʻao.

Hoʻokomo pinepine nā ʻaoʻao i nā hopena ma muli o nā pilala pono ʻole ke koho ʻia. Eia nō naʻe, i kekahi mau hihia, ʻaʻole i pili nā hopena pili i ka dosis o ka lāʻau.

ʻO ka hopena ʻokoʻa ka hiʻohiʻona no nā statins:

nā ʻōpū, a hiki i ke kūkulu ʻana o nā ʻeha puʻuwai a me nā migraines,
pilikia kūwili,
nā hopohopo e hiamoe ana a me ka hiamoe,
nāwaliwali, nāwaliwali,
molepole hana
nā pepeke
Nā maʻi CNS.

ʻO ka mea paʻakikī loa a me ka hoʻopiʻi kūikawā o ka lāʻau statin ka hoʻomohala ʻana o ka rhabdomyolysis. ʻO kēia hiʻohiʻona ma muli o ka hopena o ka hopena o ka lāʻau ma luna o nā uaua mākeke.

He kūlana pōʻino loa ʻo Rhabdomyolysis e alakaʻi i ka hoʻopōʻino i nā tubula renal a me ka hoʻomohala ʻana o ka hana ʻole o ka aʻalolo.

Ke koho ʻana i kahi huahana olakino

No ka hoʻoholoʻana i ka pono o kahi lāʻau lapaʻau hiki wale nō ke hoʻohana wale ʻia i ka mea maʻi kūikawā. I ka hoʻoponopono ʻana e nā waiwai pharmacological, ʻo Atorvastatin he hana hou aku nei i kēia mau mea hou a ikaika hou, inā mākou e lawe nei i nā ʻaina semi-synthetic i ka hoʻohālikelike. ʻO ka ʻokoʻa nui ka waiho ʻana i nā hiʻohiʻona o ka synthesis a me pharmacodynamics o nā lāʻau.

ʻO ka hoʻohana ʻana o ka atorvastatin e hoʻopili i ka hōʻiliʻili o kahi huahana mea kūlohelohe - sterol, e hoʻonāukiuki i ka hopena maikaʻi ʻana i nā hana ʻōiwi. Hoʻohui pū kekahi ʻo Simvastatin i nā hopena myotoxic, akā i ka meaʻoi loa.

Hōʻike ka hoʻohālikelike hoʻohālikelike o nā lāʻau lapaʻau me ka kōkua ʻana o Atorvastatin i ka kolesterere wikiwiki wikiwiki. ʻO kēia kumu nui ka pane nui ma waena o nā mea hana ʻelua.

Wahi a ke aʻo ʻana, he pono ka hui hoʻohui me nā lāʻau phyto. Loaʻa i kēia hui hui kahi hopena potentiating, a hoʻohaʻahaʻa i nā hopena ʻaoʻao o nā kālā. ʻAʻole kēia e ʻōlelo i nā lāʻau lapaʻau, ʻano, ʻo Ateroklefit a ʻo Ravisol ka mea i ʻoi aku ka maikaʻi ma mua o ka Atorvastatin klasik, akā ʻoi aku ka maikaʻi o ka lawe ʻana iā lākou i ka hui pū.

Wahi a nā helu helu, ua hōʻoia ʻia ka hoʻohana ʻia ʻana o Atorvastatin no nā ʻano kiʻekiʻe o ka maʻi, ʻoiai ua ʻōlelo ʻia ʻo Simvastatin no prophylaxis. Pono ʻoe e kūʻai i nā lāʻau lapaʻau ma nā kūloko pili ʻole a i ʻole nā lāʻau lapaʻau pūnaewele pūnaewele. Kūlike ke kumukūʻai ma Lūkia a me CIS i ka mea hana.

Loaʻa nā pono o ka hoʻohana ʻana i nā statins i ke wikiō ma kēia ʻatikala.

Hoʻohanohano Atorvastatin

ʻO Atorvastatin e pili ana i nā lāʻau lapaʻau lipid-hamina mai ka pae o statins. Atorvastatin calcium trihydrate (10.84 mg) kahi mea ikaika e hana i ka synthesis o kolala. Mālama kēia waiwai i ka hoʻemi ʻana i ka nui o nā lipoproteins low density (LDL) a me ka density kiʻekiʻe (HDL), a laila e pale ai i ka hoʻokumu ʻana o nā kolamu polenika.

Ua kuhikuhi ʻia ʻo Atorvastatin a i ʻole Simvastatin e hoʻohaʻahaʻa i ka cholesterol a hoʻomaikaʻi i nā hana metabolic.

Ma hope o ka nānā ʻana, ua komo ka papa i ka ʻōpū liʻiliʻi, kahi e komo koke ai i ka ʻōnaehana ʻōnaehana ma o kona pā. ʻO ka bioavailability o ka mea hana ikaika he 60%. Mālama kekahi wahi o ka enzyatic i ke ʻano o ka lāʻau lapaʻau, a hoʻihoʻi ʻia nā koena mai ke kino me ka feces, ka urine a me ka humu.

Ka hapanui koleke i ka atherosclerosis, ke kaomi o nā poli i loko o ka capilaries a nui a liʻiliʻi paha ke kumu nui no ka hoʻohana ʻana i Atorvastatin. Noi ʻia nō hoʻi ke kuhikuhi i ka lāʻau lapaʻau no ka pale ʻana i kēia mau maʻi:

diabetes type 2
puʻuwai puʻuwai
māhā
haʻi maʻi
ʻinalelo angina pectoris
ischemia o ka puʻuwai.

ʻO Atorvastatin e pili ana i nā lāʻau lapaʻau lipid-hamina mai ka pae o statins.

Loaʻa i hiki i Atorvastatin ke hōʻuluʻulu i loko o ke kino me ka hoʻohana mau ʻana a me kekahi mau pathologies, no ka laʻana, inā he kīpona a pōpō paha ka lolo. I kēia hihia, ua nānā ʻia ka hopena o ka hopena o ka lāʻau. Hiki i ka mea maʻi ke hoʻopiʻi i ke maʻi, ka ʻeha, ka palupalu nui, a me ka hana wikiwiki. Inā ʻae ʻoe i kēia mau ʻōuli a pau, a laila ke kiʻekiʻe ka hopena o ka laʻala o ke kino.

Nā hiʻohiʻona o ka simvastatin

No ka lāʻau ʻo Simvastatin no ka pūʻulu o nā statins. ʻO ka hana ikaika o ka lāʻau ka simvastatin. Hoʻokomo nā mea hoihoi:

titanium hone
lactose
povidone
citric acid
ascorbic acid
magnesium stearate a me nā mea ʻē aʻe.

He kiʻekiʻe ke kūpaʻa o Simvastatin. Loaʻa ka lōʻihi o ke koina o ka waiwai ikaika i ke koko ma kahi o 1-1,5 mau hola ma hope o ka hoʻokele ʻana. Ma hope o nā hola 12, ua hoʻemi ʻia kēia pae ma 90%. ʻO ke ala nui o ka excretion ma waena o nā ʻōpū, ma o nā keiki, ma o 10-15% o ka hana ikaika i excreted.

ʻO ke kumu nui o ka lāʻau lapaʻau e hoʻohaʻahaʻa i ka cholesterol i loko o nā maʻi cardiovascular. Hoʻoikaika ʻia ka lāʻau lapaʻau i loko o ia mau hihia:

kiʻekiʻe ka uluʻana o ka atherosclerosis,
ʻO ka hypercholesterolemia mua (type II a me II b),
hypercholesterolemia a me hypertriglyceridemia,
no ka pale ʻana i ka hala ʻana o myocardial infarction, stroke, ischemic attack, atherosclerosis of the heart vessel.

ʻO ke kumu nui o ka hoʻohana ʻana iā Simvastatin he hoʻohaʻahaʻa i ka cholesterol i loko o nā maʻi cardiovascular.

Hoʻohālikelike o Atorvastatin a me Simvastatin

Kūkākūkā i kahi lāʻau lapaʻau a koho i ke hoʻoponopono ʻia dosage ka mea nui wale nō ka mea e mālama i ka manawa ʻaʻole o ka maʻi wale nō, akā ke ʻano ponoʻī o ke kino.

ʻO nā lāʻau ʻelua e hoʻohana pū ʻia i ka cardiology no ka mālama ʻana a me ka pale ʻana i nā maʻi a me ka vascular.

ʻO Atorvastatin a me Simvastatin nā lāʻau lapaʻau maikaʻi a loaʻa hoʻokahi pahuhopu - e hoʻohaʻahaʻa ana i ke kolamu koko.

Hoʻohui pū ʻia nō hoʻi lākou e kēia mau hiʻohiʻona:

ʻO nā lāʻau lapaʻau ke ʻano o nā ʻano wai like ʻole, akā aia ka lactose i nā mea ʻelua. No laila, pono e hoʻokaʻawale ʻia lākou me ka ʻike ʻana i kēia māhele kōkua.
ʻO ka hopena hopena i ke ʻano o ka dizziness ka mea e hōʻike ai i nā lāʻau ʻelua. No kēia kumu, i ka wā o ka mālama ʻana, pono ʻoe e hōʻole i ka lele i kahi kaʻa a hana pū me nā hana kūpono.
Contraindicated ʻo ka lāʻau lapaʻau me nā lipid-hoʻohaʻahaʻa i nā lāʻau lapaʻau, no ka mea e hoʻomohala ai myopathy. Inā, e kū'ē i ke ʻano o ke aʻoaʻo me ka Atorvastatin a i Simvastatin, kū mai ke ʻano a me ke ʻano o ka ʻehaʻehā, a laila e haʻalele ʻia ka lāʻau lapaʻau, e hoʻololi iā lākou me nā analogues.
ʻO ka ʻōpū a me ka lactation kahi hui hou ʻē aʻe. Pono nā wahine i ka wā mālama e hoʻohana i ka ʻekena.
Me ka hoʻohana lōʻihi a me ka overdose, ʻoi ka nui o ka hopena o nā ʻaoʻao. I ia mau pilikia, e ʻoi aku ana ka nui o ka pūpū a me ka ate. No laila, pāpā paʻa loa ʻia i ka nui o ke ʻano i kau ʻia e ke kauka.

ʻOkoʻa ka ʻokoʻa

ʻO ka mea nui ka hoʻohālikelike o ka mākaukau ʻana o ka mākaukau me ka like ʻole o ka hana ikaika. No laila, ʻo ka atorvastatin e pili ana i ka statins statins, aia ka lōʻihi o ka hopena therapeutic. ʻO Simvastatin kahi statin kūlohelohe me kahi hopena pōkole.

ʻO ka mea ikaika o Atorvastatin ka mea ikaika aku, no laila, ua loaʻa kēia lāʻau lapaʻau i nā contraindications. E pili ana kēia:

hapai a me lactation,
makahiki i ke 10 mau makahiki
humuho waiwa,
ua hoʻonui nui ʻia o nā transaminases i loko o ke koko,
maʻi pili i ka lactose,
mai nā maʻi ʻeha i ka wāʻeha.

ʻAʻole ʻōlelo ʻo Simvastatin i hoʻohana no ka hoʻohana ʻana i nā hihia i lalo aʻe:

hypersensitivity i nā māhele o ka lāʻau lapaʻau,
maʻi ate
makahiki ʻokoʻa
hapai a me lactation,
hōʻoki ka ʻāʻā o nā iwi.

ʻAʻole pono ke hoʻohana pū ʻia ʻo Atorvastatin i nā manawa like me nā loea antibacterial a me antimicrobial. ʻAʻole hiki ke hoʻohui pū ʻia ka Simvastatin me nā proteamine inhibitor a me nā anticoagulants. Mai ʻai i ka ʻōpala ʻai a inu ʻole i ka wai ʻona i ka wā e mālama ai me nā papa. hiki i kēia hoʻohui ke hoʻonui i ke kāʻei o ka waiwai i loko o ke koko.

Hiki i nā hopena ʻokoʻa ke hoʻoiho iā Simvastatin:

pilikia pilikia
ʻōpala
poʻomanaʻo
ka hōʻino ʻana i ka hoʻāʻo ʻana a me ka hihiʻo (ʻokoʻa),
hoʻonui ka ESR, kahi hoʻemi i loko o nā platelets a me nā ʻoka koko ʻulaʻula.

I ka wā maʻi me ka Atorvastatin, hiki i nā mea maʻi ke loaʻa i ka tinnitus, nā pilikia hoʻomanaʻo, a me kahi manaʻo o ka mau ʻana o ka lohi.

E kūʻē i ke kua mua o ka lawe ʻana iā Simvastatin, hiki i nā ʻeha ke hōʻeha.

Hōʻike ʻia nā Hemodialysis i nā hihia o kahi overdose o simvastatin. A he mea waiwai ʻole kēia hana i ka wā like me Atorvastatin.

ʻOi ka uku

Kūʻai ke kumukūʻai o nā lāʻau lapaʻau ma ka ʻāina o ka hana a me ka dosage.

ʻO Simvastatin i hua ʻia i nā ʻāina he nui, ʻo ia hoʻi ʻo Russia, Farani, Serbia, Hungary, a me ka Czech Republic. ʻO ke kumu kūʻai o kahi pākahi o 30 mau papa o 20 mg e 50-100 mau rubles. ʻO ke kumukūʻai no ka hoʻoulu ʻana i kahi lāʻau lapaʻau (20 pcs. No 20 mg) i hoʻouka ʻia ma Czech Republic ma kahi o 230-270 rubles.

Hiki ke kūʻai ʻia ʻo Atorvastatin o ka hana Lūkini ma nā lāʻau lapaʻau ma kēia kumukūʻai.

110 ka ʻōpala - 30 pcs. 10 mg pākahi
190 ʻōpala - 30 pcs. 20 mg i kēlā me kēia
610 rub - 90 pcs. 20 mg i kēlā me kēia.

ʻO kahi maikaʻi loa - atorvastatin a simvastatin

ʻO ka kauka hele wale nō e hiki ke haʻi aku i ka lāʻau a ka maikaʻi ma hope o ka hoʻopaʻa ʻana i ka mea maʻi, akā aia kekahi mau mea nui o nā lāʻau lapaʻau.

Hiki ke loaʻa kahi hopena kūpono kūpono me ka Atorvastatin, ʻo loaʻa ia i kahi mea ikaika me kahi hopena ikaika loa.
Hoʻokomo ʻo Simvastatin i nā hopena liʻiliʻi, ʻo ia ka mea o ka pono o kēia lāʻau lapaʻau. I ka wā e hoʻohana pololei ai, ʻaʻole e hōʻiliʻili nā mea make i loko o ke kino.
I ka hopena o nā noiʻi maʻi lapaʻau o nā lāʻau lapaʻau, ua hōʻoia ʻia e hoʻohemo nui ʻia ʻo Simvastatin i ka kolesteroli hōʻino ʻia ma 25%, a me Atorvastatin - e 50%.

No laila, no ka lōʻihi o ka mālamaʻana i nā pathologies, pono ʻo Atorvastatin e pono ai, a no ka pale ʻana i nā maʻi vascular, ʻoi aku ka maikaʻi o ka hoʻohana ʻana iā Simvastatin.

Nā ʻala - he aha ia?

ʻO kēia mau lāʻau lapaʻau e kau mua ma ka helu o nā mea maʻi e lawe iā lākou. Hoʻokumu ka hana o ka hana o ka lipid-hoʻemi haʻahaʻa i ka pale ʻana i nā enzyme me ka inoa paʻakikī "HMG-CoA reductase", kahi e hoʻonāukiuki ai ka hana o ka kolamu hou i loko o ka puʻuwai.

Hoʻopau nā poʻomanaʻo i nā moku i hōʻino ʻia inā ʻaʻole i ʻike ʻia ka atherosclerosis, akā ua hōʻiliʻili ke kolu "hewa" i nā paia. Hoʻomaikaʻi lākou i nā lāʻau lapaʻau a me nā kaha rheological o ke koko: ka hoʻohaʻahaʻa haʻahaʻa, pale i ka nānāʻana o nā māka koko.

ʻO ka lāʻau kūpono loa no ka kolamu ka hanauna hou o ka atorvastatin, cerivastatin, rosuvastatin a me pitavastatin.

ʻAʻole hōʻemi wale nā poʻomanaʻo i ka neʻe o ka cholesterol maikaʻi ʻole, akā e hoʻonui pū i ka ʻike o ka pono. Hiki ke ʻike ʻia ka hopena mai ka hoʻohana ʻana i nā lāʻau lapaʻau o kēia pūʻulu i loko o hoʻokahi mahina ma hope o ka hana maʻamau. Ua kuhikuhi ʻia nā statins i hoʻokahi lā i ka pō, ke ʻae ʻia kahi hui ʻana i hoʻokahi papaʻaina a me nā ʻoihana cardiological.

ʻAʻole ʻike ʻia ka mālama ʻana iā ia iho me nā statins, no ka mea, ua kau ʻia nā ʻōlelo a ke kauka i nā hopena o nā hoʻokolohua o ke koko biochemical, ma nā ʻano, i nā hōʻike LDL. Inā ʻaʻoleʻoi aku kēia hōʻailona ma mua o 6.5 mmol / l, e hoʻemi ʻia ia e ka hoʻoponopono ʻana i ka meaʻai a me ka noho ʻana. ʻAʻole lawa ka nui o kēia mau hana, ma hope o ʻeono mahina e kuhikuhi ai ke kauka i nā statins.

ʻAʻole i maʻalahi i ka mea i uninitiated ʻike ʻole: rosuvastatin a me atorvastatin - he aha ka ʻokoʻa ma waena o kēia mau mea like ʻole e like me nā pale o ka ʻaina e hoʻoulu ai i ka kolamu? ʻO Rosuvastatin kahi lāʻau lapaʻau hou hou e hoʻohālikelike nei i kona mau poʻe mua.

I nā dosis kūlike i ka atorvastatin, ʻoi aku ia he hopena hou. ʻO kahi hoʻopaʻapaʻa koʻikoʻi ʻo ia ka haʻahaʻa haʻahaʻa.

Hiki iā ʻoe ke aʻo hou e pili ana i ka pehea e lawe pololei ai i statins mai ke wikiō.

Nā lāʻau lapaʻau e ola-lōʻihi

Inā ʻaʻole i kūlohelohe ka lāʻau lapaʻau i nā mea ʻole i hana ʻole ʻia, ma ka maʻamau ka hōʻike maʻamau no ka koho ʻana i ka poʻe pale i ka hypercholesterolemia (me ka nui o ke kūmole o kahi kolamu o kahi ʻano genetic).

I kēia lā, ua kuhikuhi ʻia nā statins me nā kolesterol maʻamau:

ʻO ka mea maʻi me ka maʻi puʻuwai ischemic,
Ma hope o kaʻaila myocardial,
Ma hope o kekahi hana ma ka coronary arteries (ka hoʻoku ʻana, bypass surgery),
Inā loaʻa i ka mea maʻi ka maʻi ʻeha,
Me ka maʻi maʻi me ka LDL kiʻekiʻe.

ʻOi aku ka nui o nā ʻano o nā statins ma mua o ka maʻamau normalization o ke kolamu, ka honua - kēia mau lāʻau lapaʻau e hoʻolōʻihi i ke ola. ʻO ka mea hoʻoholo i ka koho ʻana i nā statins e neʻe nei i ka atherosclerosis holomua. ʻO kēia mau ala āpau, a me ka predisposition hoʻoilina, hāʻawi i ka nui o ka hōʻino o ka hōʻino o ka vascular.

ʻO kēia papa o nā lāʻau lapaʻau e contraindicated ma ka maʻi hepatitis, cirrhosis a me nā ʻaoʻao ʻē aʻe. ʻAʻole paipai ʻia nā statins i ka wā hāpai a ma ka wā hānai. ʻAʻole lawe ʻia nā wahine o ka hānau keiki ʻana inā ʻaʻole lākou e pale ʻia e nā mea hoʻohālike kūpono. Mai kuhikuhi i nā statins inā ʻike ʻia nā maʻi kūlohelohe.

ʻAʻole hopena o nā statins i nā kaʻina ʻē aʻe - ʻo ka hoʻololi ʻana i nā protein, nā pale, nā hoʻomaʻamaʻa, no laila hiki ke palekana pono e ka maʻi maʻi, nā maʻi me ka gout a me nā maʻi ʻē aʻe.

Nā hopena hopena

Kēia mau lāʻau lapaʻau i loko o ka hana i kau ʻia i nā mana paʻa loa no nā hopena pili. ʻO Rosuvastatin, no ka laʻana, ua aʻo ʻia no ʻelua makahiki, atorvasin, lovastatin a me simvastatin no 3-5 makahiki. Ma kahi o nā manaʻo hōʻoiaʻiʻo e pili ana i ka hoʻopaʻa ʻana i ka hōʻeha ʻana o ka puʻuwai, aia kekahi mau hoʻohui.

Loaʻa ka hopena pōʻino ma ka hopena lōʻihi me nā statins ʻaʻole iʻoi aku ma mua o 1%. I waena o kēia mau hopena:

ʻO ka maʻi hiamoe
Ke hoʻolohe ʻia nei
Nāwaliwali a me ka hōʻeha o nā ʻōpū a me nā hui,
Hoʻoikaika kumuhana
Hoʻololi i ka nānā ʻono,
Tachycardia
Nā hāʻule koko,
Hoʻemi i ka hoʻāʻo pākeke,
Nosebleeds
Nā maʻi Dyspeptic
Nā hana ʻino i ke ʻano o ke ʻano o ka pēpē a me ke urination,
Hoʻopau i nā hana moekolohe,
Hoʻonui kaho
Allergy

ʻOi aku ma mua o ka 1% o nā mea maʻi e loaʻa i ka maʻi, ka ʻeha o ka umauma, ka umauma, ka pupuhi, ke kiʻekiʻe ʻana o ka naʻau o ka lā o ka lā, ka ʻeha o ka ʻili (mai ʻulaʻula a hiki i ka eczema).

E heluhelu hou e pili ana inā loaʻa mau ka pono e lawe statins - ma kēia wikiō

Ka kuʻikahi me nā lāʻau lapaʻau ʻē aʻe

Manaʻo ʻo WHO a me ka ʻAmelika ʻAmelika Hui Pūʻulu i nā statins ma ke ʻano he mea nui i ka mālama ʻana i ka maʻi ʻalapau coronary inā lawa ka nui o ka hoʻopiʻi ʻana. ʻO ke koho ʻana i kēia ʻano o nā mea maʻi e wehewehe wale nō ʻaʻole lawa ka kolamu haʻahaʻa.

Pākuʻina pilikino e pili ana:

mau mea kālai-blockers (e like me bisoprolol, atenolol, metoprolol),
ʻO nā mea hoʻohui Antiplatelet (ma ke ʻano o aspirin, aspirin, thrombosis ass),
ʻO nā mea hoʻopaʻa o ACE (perindopril, quadripril, enalapril),
Nā ʻāpana

Ua hōʻoia ʻia nā noiʻi lehulehu i ka palekana o ka hoʻohana ʻana i kēia mau lāʻau lapaʻau i hui pū ʻia.

I kekahi mau hihia, i ka hui pū ʻana o nā lāʻau like ʻole i loko o hoʻokahi papa (no ka laʻana, pravastatin + aspirin) hōʻemi i ka hōʻeha o ka hōʻeha ʻana i ka puʻuwai (ʻokoʻa wale ʻo 7.6%) i hoʻohālikelike ʻia i ka hoʻohana hoʻokaʻawale ʻana o kēia mau lāʻau (9% no pravastatin a me 11% no ka aspirin).

Ma nā ʻano kuʻuna, ʻōlelo ʻia nā statins no ka pō ʻokoʻa, kahi kaʻawale mai nā ʻano lāʻau ʻē aʻe. I kēia mau lā, hāʻawi nā lāʻau lapaʻau i ka hui ʻana o kekahi mau lāʻau lapaʻau i loko o hoʻokahi papa, ʻo ia ka koho e koho ai no nā kauka. I waena o kēia mau lāʻau lapaʻau he duplexor, caduet, hui pū i ka atorvastatin a me ka amlodipine i hoʻokahi papa.

Ke hāʻawi nei i ka hōʻike a me kahi hana hou no nā hopena paʻakikī - Polypill.

Inā heʻoi aku ka nui o ka kolamu 7.4 mmol / l, ua hui pū ʻia nā statins me nā fibrates (kahi hui hou o ka cholesterol hoʻemi haʻahaʻa). ʻO kēlā mau statins ka mea e ʻoi loa a palekana ma kahi hihia, ke hoʻoholo nei ke kauka, ka nānā ʻana i nā maʻi āpau hiki.

ʻAʻole hiki ke ʻoluʻolu a lawe i nā statins me kahi paila o ka huehue ʻili, no ka mea e loaʻa ai nā mea i hoʻokaʻawale i ke kaomi ʻana o nā statins. Hoʻopilikia ka nui o ke kō i ke koko ma o ka hōʻiliʻili ʻana o nā toxins.

ʻO ka launa ʻole paʻa me kēia pūʻulu o nā lāʻau lapaʻau me ka wai ʻawaʻawa a me kekahi mau meaola me nā ʻano hoʻonaninani: e like me ka clarithromycin a me ka erythromycin, e hana ana i ka kaumaha hou ma luna o ke ake.

ʻO nā antibiotics'ē aʻe e kūpono like me nā lāʻau lapaʻau e hoʻohaʻahaʻa i ka cholesterol. Pono ke nānā i ke ʻano o ka puʻuwai i kēlā me kēia 3 mahina, e hōʻike ana i loko o ke koko i ka mea e hōʻike ai i nā kuhikuhi o nā aila ate.

ʻO nā pono a me nā hōʻino o nā statins

Ka nānā ʻana i nā ʻoni, ʻike nā maʻi maʻi maʻamau i ka hopena o nā lāʻau lapaʻau: pehea ka nui o nā pōmaikaʻi o nā statins i hiki ke hōʻeha ʻia e kamaʻilio nui ʻia. ʻO nā ʻike e pili ana i nā lāʻau hou me ka liʻiliʻi o nā hopena kūpono ʻole e kōkua i ka hoʻohemo ʻana i nā kānalua.

Loaʻa nā pono kūpono i ka ʻoluʻolu o ko lākou pono:

ʻO 40% ka emi o ka make o ka naʻau ma mua o 5 mau makahiki.
Hoʻemi i ka hopena o ka hoʻomohala ʻana i ka puʻuwai a me ka hōʻeha ʻana ma ka 30%.
E hoʻemi i ka haʻahaʻa e 45-55% (me ka hana maʻamau a me ka manawa lōʻihi). No ke ʻano ʻana i ka dinamika, pono ʻoe e nānā i ke koko i ke koko no ka cholesterol.
ʻO ka hoʻohana ʻana i kahi laʻau therapeutic o ka hanauna hou o nā statins, ʻaʻole ia e hana i nā hopena hopena. No ka manawa lōʻihi i manaʻoʻiʻo ʻia e hiki i nā statins ke hoʻonui i ka nui o ka hōʻemi ʻana i ka maʻi paleka o ke ake, type 2 diabetes mellitus, cataracts, dementia. Ua hōʻole ka noiʻi hou i kēia ʻano kaomi a hōʻoia i nā hopena like ʻole e kū aʻe i nā kumu ʻē aʻe. Mai 1996 mai, ua mākaʻikaʻi ʻo Denemaka i ka maʻi diabetes. ʻO ka hopena o nā hoʻopiʻi o ka maʻi maʻi e like me ka retinopathy, polyneuropathy i hōʻemi e 40 a me 34%.
Nui kahi koho o nā lāʻau like ʻole o nā ʻano lāʻau like ʻole me kahi mea hana maʻamau. Ua nīnau pinepine nā kumuhana Thematic: simvastatin a atorvastatin - ʻoi aku ka maikaʻi? ʻO ke koho mua he mea kūpaʻa ia o nā statins kūlohelohe, ʻo ka lua o kahi mea synthetic modern. Me nā ʻokoʻa āpau o ke hoʻolālā a me nā ala metabolic, he hopena lapaʻau like ka hopena. Kūʻokoʻa lākou i ke kumu kūʻai: ʻoi aku ka liʻiliʻi o ka simvostatin ma ka atorvastatin.

I waena o nā hemahema, hiki i kekahi ke hoʻomaopopo i ke kumukūʻai kiʻekiʻe o ke keʻa, ka rosucard, leskol forte a me nā mea āpau mua o nā hanauna hou loa, no kēlā me kēia inoa o nā lāʻau lapaʻau i hiki ke koho mau iā ʻoe i kahi kuʻuna me ka uku kumukūʻai.

ʻO ka ʻike kumu o ke loea Farani Debreu ma ka pilikia "ʻo ka hoʻopiʻi a me ka ʻoluʻolu o ka mālama statin" nānā i ke wikiō

Hōʻike Manaʻo

ʻO ka papa inoa o nā statins - nā lāʻau lapaʻau e ʻike pinepine ʻia nā inoa i nā papa kauka ma ka papa ʻaina.

ʻAi a me ka ʻekemu o ka waihona kumu

ʻO nā lāʻau lapaʻau mua

ʻO nā lāʻau lapaʻau ka lua

Nā lāʻamau o nā hua lapaʻau

ʻO nā lāʻau lapaʻau ʻehā

ʻĀina hana	Aia ma hea lākou e hana ai	ʻO ke kumukūʻai kūʻai, rub.
Simvastatin	Vasilip (10, 20, 40 mg)	I Slovenia	444
ʻGallelo (10, 20 a 40)	I ka ʻIseraʻela a me ka Czech Republic	461
Simvakard (10, 20, 40)	I ka Czech Republic	332
Simlo (10, 20, 40)	In india	302
Simvastatin (10, 20.40)	Ma ka Lūkini Russian, Serbia	125
Pravastatin	Lipostat (10, 20)	Ma ka Lūkini Lūkini, Italia, USA	170
Lovastatin	Holla (20)	I Slovenia	323
Kaikuahine (20, 40)	Ma ka Lūkini Kūkala	306
Fluvastatin	Leskol Forte (80)	I Switzerland, Sepania	2315
Atorvastatin	Kapukula (20)	I Inia, RF	344
Liprimar (10, 20, 40, 80)	I Kelemānia, ʻAmelika, ʻInelani	944
Tulip (10, 20, 40)	I Slovenia, Suetena	772
Kauoha (10, 40)	I ka Czech Republic	852
Atoris (10, 20, 30, 40)	I Slovenia, ka Russian Federation	859
Rosuvastatin	Kaikaha (5, 10, 20, 40)	Ma ka Lūkini Russian, ʻEnelani, Kelemānia	1367
Rosucard (10, 20, 40)	I ka Czech Republic	1400
Rosulip (10, 20)	I Hungary	771
Kapua (5, 10, 20)	I ka ʻIseraʻela	531
Pitavastatin	Livazo (1, 2, 4 mg)	Ma Italia	2350

Kahi kūwaho ke kumukūʻai no nā statins, akā naʻe he aneane ʻole ka lāʻau lapaʻau o nā mea kanu ma mua o nā lāʻau lapaʻau mua mai ka papa inoa, no laila hiki i nā mea āpau ke koho i kahi analog no lākou iho e like me kā lākou kālā.

ʻO nā ala o ka hoʻoponopono ʻana i ka pae cholesterol kiʻekiʻe

Inā hoʻonui iki ka kolamu a ʻaʻohe ʻōpilikia kūikawā o ka pilikia o ka naʻau, e hoʻāʻo e hana i ka pae o kaʻai. ʻO ka pīhoihoi, kekahi mau mea kanu mea kanu i nā kūlohelohe. ʻO ka mea i aʻo ʻia ma kēia ka hiki ʻana o ke kāleka a me ka turmeric.

Hoʻohui iā lākou, nā meaʻai kūpono e pili ana i ka mālama wela wela o nā huahana (keʻaila, ke kuke, ke kī ʻia a ʻohu ʻia paha). Hoʻokomo ʻia ka momona momona a me nā pākoki, aia nā palena ma ka nui o nāʻano, ka pāʻai a me ka offal.

He mea nui ke kolesterol no ke kino ke ʻano hale no nā ʻili, no laila he mea nui ʻole ka haʻalele, akā e kaupalena wale nō i ka inu ʻana o kekahi mau huahana.

ʻO ka lau momona (nā mea kanu, nā cereals, legumes) a me nā momona momona o polyunsaturated Щ-3 (iʻa ʻulaʻula, nā iʻa ʻaʻa), e hoʻomaikaʻi ana i ka metabolism cholesterol, pono.

Inā hāʻawi nā kumu i luna aʻe e hāʻawi i ka hopena i makemake ʻia, ua kauoha ʻia nā lāʻau lapaʻau lipid-hoʻemi.

I ka hopena, pono ke koʻikoʻi nei, me ka makaʻu ʻole o nā maʻi āpau i ka lawe ʻana i nā statins - nā lāʻau lapaʻau no ka hoʻohaʻahaʻa i ka kolala - a me ka manaʻo ākea e pili ana i ka hopena maikaʻi o kēlā ʻano hoʻomaʻamaʻa, ʻoluʻolu ke kumu o kā lākou maʻi atherosclerosis me nā hopena koʻikoʻi, no ka mea e hiki i kēia mau lāʻau ke hoʻolōʻihi i ke ola. hoʻomaikaʻi i kona ʻano.

Heʻoiaʻiʻo, ʻoi aku ka maʻalahi o ka ʻawa he inu, akā me ka hoʻonui ʻia o ka koleko me ka ʻole o ka hōʻailona liʻiliʻi o ka hōʻino ʻia o ka vascular, ʻoi aku ka maikaʻi o ka hoʻopili pono ʻana i ke ola olakino a nānā pono ʻia i nā kolesterol.

Ua haʻi ko Professor E. Malysheva kūleʻa e pili ana i nā stins e hoʻolōʻihi i ke ola

Atorvastatin Papa ʻauhau

Nā hopena haukapila o ka atorvastatin
Nā maʻi maʻi	ʻ .lelo hopena
ʻO nā pākeke me ka maʻi puʻukū coronary me ka hui pū ʻana o nā mea pili i ka pilikia (mōʻaukala ʻohana o ka maʻi artery coronary ʻokoʻa, kūlia hilinaʻi, ka ʻaluna, hyperlipidemia, hypertension, makahiki)	Hoʻemi huna:

ʻO ka hoʻomohala ʻana o ka angina pectoris a me ka pono o ka revascularization.
ʻOkelelo.
Myocardial infarction.

ʻO nā mea maʻi diabetes type 2 ʻaʻole i loaʻa ka maʻi ararone coronary i hui pū me nā mea pili i ke kino (hypertension, ulaula, ʻalowa, albuminuria, retinopathy)Hoʻemi huna:

ʻOkelelo.
Myocardial infarction.

ʻO nā maʻi me ka maʻi naʻau coronary koʻikoʻiHoʻemi huna:

ʻO ka halemai ma muli o ka hiki ʻana o ka puʻuwai aloha.
ʻAno hōʻeha a me ka maʻi nonfatal.
ʻO kahi kīpē i pili ʻole i ka maʻi.
ʻO ka hoʻomohala ʻana o ka angina pectoris a me ka pono o ka revascularization.

Rosuvastatin

He helu statin aila kēia me nā mea lapaʻau i hōʻoia ʻia, i manaʻo ʻia ka waiwai maikaʻi loa no ka hoʻohana lōʻihi. Hōʻike ʻia ka Rosuvastatin no ka hoʻohana ʻana i nā poʻe maʻi me ka maʻi myocardial acute, hypertension Second, stroke, atherosclerosis. Manaʻo ʻia ʻo Statin i ka palekana, akā ʻoi aku ka maikaʻi ma mua o ka atorvastatin.

Ka ʻānō maʻamau ka maʻamau no ka hui ʻo pharmacological o nā statins. I ka papa mua, lawe ʻia nā lāʻau lapaʻau i ka 10 mg i ka lā. I ka hala ʻole o nā hopena hopena, hiki ke hoʻonui ʻia ka nui o ka lā i ka 40 mg. Kahi ʻia nā ʻano like o kēia ʻano o ka statin palekana no ka poʻe maʻi me ke kolamu o ke koko, ke ʻano ʻōpili, a me ka hypercholesterolemia hoʻoilina.

Hoʻopau kūleʻa ʻo Rosuvastatin i ka piʻi o LDL. Hiki i kona hiki ke hoʻokaʻawale koke i ka wai me ka hoʻomaʻamaʻa ʻole i ka hana o nā pūpuna o nā ate. Ua hōʻike ʻia nā hoʻokolohua ʻē aʻe i ka palekana o ka hoʻohana ʻana i kēia lāʻau lapaʻau maikaʻi no ka hana naʻau. Hoʻohālikelike ʻia me nā statins lipophilic, manaʻo ʻia ʻo Rosuvastatin i kahi lāʻau hōʻoluʻolu a palekana hoʻi. Eia kekahi, ʻaʻole ia e luku aku i nā hua māhu.

Pahu dinamika maikaʻi mai ka maʻi me ka rosuvastatin i ʻike ʻia ma ka hoʻomaka ʻana o ka mālama ʻana. Ma hope o kahi mahina o ka hoʻohana maʻamau, hiki i ka lāʻau lapaʻau kona nui o ka hiki. Wahi a STELLAR, ma kēlā me kēia awelika o 40 mg, kahi hōʻemi i LDL e kahi hapa o ka hapalua i hoʻopaʻa ʻia, me ka piʻi o HDL e 10%.

Ua hōʻike nā haʻawina hoʻohālikelike o LUNAR i kahi mea liʻiliʻi o Rosuvastatin, i lawe ʻia ma 40 mg i kēlā me kēia lā, ma luna o Atorvastatin me kahi maʻamau o kēlā me kēia lā he 80 mg. Nā hōʻailona kikoʻī o ka hāʻule ʻana o ka LDL he 47 a me 43%, kēlā me kēia. ʻO ke kolamu o ka "maikaʻi", ʻo ka hoʻohana ʻana i kēlā me kēia lā he 40 mg o Rosuvastatin i hoʻonui i ka HDL e ka 12%, aʻo ka nui o ka lipoproteins like mai 80 mg o Atorvastatin ʻaʻole iʻoi aku ma mua o 6%.

Ua paʻi ʻia kekahi nūhou ʻepekema hana hou e loaʻa i nā hopena o nā hōʻike olakino hou loa, e like me ke olakino e pili ana i nā lāʻau lapaʻau i luna ke ʻano o ka hana o nā keiki.

Nui a nā lāʻau lapaʻau e loaʻa ana nā ʻano hana like me Rosuvastatin, a no laila hiki ke hoʻohana ʻia i kahi koho hou. Ma mua o ka hoʻohana ʻia ʻana o ia mau mea, he mea pono ia e ʻōlelo aku me kāu kauka. Hoʻopili kēia mau mea:

Hoʻopiʻi ʻo Simvastatin

Nā mea hoʻohālikelike i kēia ʻano o ka statin:

Hiki paha ke hoʻemi i nā hopena o ka maʻi cardiovascular, me ka kiʻekiʻe o ka kolamu nui, me ka ʻole o ka lawe ʻana i nā lāʻau lapaʻau me nā hopena ʻaoʻao? Hōʻike ka pane i ka ʻā ʻana o nā papa hoʻoikaika, me ka ʻai pono hoʻi. Hoʻohana ʻia kekahi kanaka no ka mālama ʻana i nā pilikia olakino me nā lāʻau aʻe e poina ai ia e pili ana i ka ikaika o kona kino. ʻO ka hoʻololi ʻana i ka huli ʻana i kahi panacea i ke ʻano o ka paila e hiki ke lilo i kaʻai pono ʻole.

Hoʻolohe Kiihewa nā paule a pau, a no kēlā me kēia kanaka ke kanaka, no laila ma mua o ka hoʻomaka ʻana i ka lawe ʻana i kekahi lāʻau lapaʻau, pono e kipa ʻoe i ke kauka.

ʻO nā kumumanaʻo no ke ate, a i ʻole, ke kāohi nei kā lākou hoʻokō i ka hanana ʻana o ke akeʻa o ke akeʻai. I ka manawa like, e hōʻemi ana i ka hopena o ka pathology vascular.

Noi ʻia nā statins no ke maʻi type 2 no ka pale ʻana i nā maʻi o ka ʻōnaehana kaomi a me ka hana naʻau maikaʻi. He hopena maikaʻi nā lāʻau lāʻau ma ka hoʻohaʻahaʻa i ka kolamu koko.

ʻAʻole nā keruna i ka hoʻohaʻahaʻa ʻana i nā lipoproteins haʻahaʻa haʻahaʻa. Me ka hana maʻamau a me ka hoʻohana pono ʻana i kēia mau lāʻau, ua hoʻopau ka kaʻina o ka maʻi i nā ʻōpala i hoʻopilikia ʻia e ka pli kolesterol.

ʻO ka hanauna hou o statins e kōkua i ke kino e hoʻohemo i ka cholesterol maikaʻi ʻole. Hana kēia ma muli o ke pani ʻana o ka hana ate, ka mea i hana e hana ai iā ia.

Nā Hōʻike Hoʻomaʻi

Olga, 37 makahiki, ʻo Veliky Novgorod

Ma hope o ka hōʻeha ʻana o ka puʻuwai, ua kauoha ʻia ʻo Simvastatin e hoʻohaʻahaʻa i ka cholesterol. Ua mau ke mālama iā 4 mau mahina a i kēia manawa ʻaʻohe hopena o nā hopena. ʻO ka mea hiki ʻole ke hoʻowahāwahā ʻia, ʻo ia ke kumukūʻai, ka liʻiliʻi - ka hana haʻahaʻa. Hōʻike pinepine ʻia ka hōʻike ʻana o ke kiʻekiʻe o ka kolamu a maikaʻi. Ua huhū ʻo Papa, no ka mea ua manaʻo nui ʻo ia no ka lāʻau. Ke manaʻoʻiʻo nei wau e kōkua ana ka simvastatin i nā hihia haʻahaʻa, ʻaʻole hoʻi i mua. Hoʻohana ʻia mākou i kēia hana i kekahi hana ʻē aʻe.

Maria Vasilievna, 57 makahiki, Murmansk

I ka hoʻokolokolo hou, ʻōlelo ke kauka i ka hoʻonui ʻia o ka cholesterol a ʻōlelo i nā statins i lawe. Lawe ʻo ia iā Simvastatin, ukali i kahi papaʻai a pili pono i ka hana pilikino. Ma hope o 2 mau mahina ua lilo au i kahi loiloi lua, kahi i hoʻi hou aku ai nā hōʻailona āpau. ʻAʻole wau e mihi i ka inu ʻana i ka lāʻau lapaʻau, ʻoiai he nui ka mea e hoʻomaopopo i ka pōʻino a me ka waiwai ʻole me koʻu ʻano koko. Ke hauʻoli nei au ua hoʻokō ʻia ka hopena. Ke manaʻo nei wau!

ʻO Galina, he 50 mau makahiki, ʻo Moscow

Ua makaʻu wau i ka lohe ʻana mai ke kauka ua ʻoi aku ma mua o 8 mau kāleka 8. Manaʻo wau e lōʻihi ka paʻakikī o ka lāʻau. Ua kuhikuhi ʻia ʻo Atorvastatin. ʻAʻole wau i manaʻolana nui i ka lāʻau lapaʻau, akā ma ka lapuwale. Ma hope o 2 mau maʻi o ka lapaʻau, hāʻule ka cholesterol i 6. ʻAʻole wau i manaʻo i ka lāʻau lapaʻau e kōkua. Makemake wau e ʻike inā ua inu paʻa wau ma ka noi o ke kauka a ʻaʻohe hopena ʻē aʻe.

ʻO nā lāʻau ʻelua e hoʻohana pū ʻia i ka cardiology no ka mālama ʻana a me ka pale ʻana i nā maʻi a me ka vascular.

Hōʻike nā kauka e pili ana i nā kauka e pili ana i Atorvastatin a me Simvastatin

ʻO Egor Alexandrovich, 44 makahiki, Moscow

ʻAʻole paʻa wau iā Simvastatin, no ka mea Manaʻo wau ia he lāʻau lapaʻau o ka makahiki i hala. I kēia manawa he mau statins hou i ʻoi aku ka maikaʻi a me ka palekana. ʻO ka eaʻi, atorvastatin. ʻAʻole hiki i kēia lāʻau lapaʻau ke hoʻohaʻahaʻa i ka pae o ka cholesterol maikaʻi ʻole, akā e hōʻemi ana i ka hopena o ka hoʻoulu ʻana o ka puʻuwai a me ka hahau. ʻO ke ʻano kūpono o ka hoʻokuʻu.

Lyubov Alekseevna, 50 makahiki, Khabarovsk

Ma ke kauka lapaʻau, hoʻāʻo wau e kuhikuhi i Atorvastatin i nā poʻe maʻi inā ʻaʻohe contraindications. Ke manaʻoʻiʻo nei au e hana mālie nei kēia lāʻau lapaʻau, me ka hoʻoluhi ʻole i ka hana o nā hana kūloko a me nā pūnaehana kino. Hoʻopiʻi pinepine nā mea maʻi i nā hopena pili, he mea nui ia. Ma hope o nā mea āpau, ʻo ka hapanui o nā penikala ke hele mai me kahi pilikia like ʻole, ka poʻe i loaʻa nā maʻi maʻi.