Ka Leo 1

ʻO nā papa i kau ʻia no ka hoʻokuʻu ʻana o Diameride i nā papa: pāwili-cylindrical, me kahi bevel, ʻae ʻia nā hōʻuluʻulu liʻiliʻi, 1 a me 3 mg kēlā me kēia ʻāpana me ke aniani brownish, 2 a me 4 mg kēlā me kēia mau mai ka melemele a i ʻole ke kukui i ka ʻalani ʻula (i nā pōpō palehū he 10 mau pā. ., ma kahi pōpō balaki a i ʻole 3 a 6 mau pāna paha).

Helu 1 papa:

• mea kūlohelohe: glimepiride - 1, 2, 3 a i ʻole 4 mg (ma nā ʻōlelo o 100% mea)
• Nā mea kōkua (1/2/3/4 mg): magnesium stearate - 0.6 / 0.6 / 1.2 / 1.2 mg, lactose monohydrate - 78.68 / 77.67 / 156.36 / 155, 34 mg, sodium croscarmellose - 4.7 / 4.7 / 9.4 / 9.4 mg, povidone - 2,5 / 2,5 / 5/5 mg, Poloxamer - 0,5 / 0.5 / 1 / 1 / mg, cellulose microcrystalline - 12/12/24/24 mg, ka wai pua ʻaole melemele - 0 / 0,03 / 0 / 0,06 mg, hoʻoneʻeke pōpilikia hao waikele - 0.02 / 0 / 0.04 / 0 mg

Nā Hoʻohui

• lactose intolerance, lactase deficiency, glucose-galactose malabsorption,
• leukopenia
• diabetes ketoacidosis, maʻi koma maʻi a me ka precoma,
• maʻi diabetes type 1
• Nā kūlana me ke komo ʻole o ka meaʻai a me ka hoʻomohala ʻana o ka hypoglycemia (me nā maʻi ʻeha),
• ka hana o ka hana o ka pūlima / puʻuwai i ka papa koʻikoʻi (me ka poʻe o ka hemodialysis,)
• hapai a me lactation,
• makahiki i 18 makahiki
• ka hoʻomanawanui ʻana o kēlā me kēia mea o ka lāʻau, me ka hypersensitivity i nā derivatives sulfonylurea a i nā lāʻau sulfonamide (e pili pū ana i ka hopena o ka hopena hypersensitivity).

Ke kuhikuhi nei iā Diameride e makaʻala i mua o nā kūlana e koi ana i ka hoʻololi ʻana o ka mea maʻi i ka hoʻomehana ʻana o ka insulin, me ka nunui o ka puhi ʻana, ka hōʻulu ʻana o ka hōʻeha nui ʻana, ka nui o nā hōʻeha pōkole, nā kīwī o ka meaʻai a me nā lāʻau mai ka gastrointestinal tract (gastric paresis, ʻeha o ka ʻawaʻawa).

Ke hāpai ʻia ka wā hāpai a i nā hihia paha o kāna hoʻolālā, pono ka wahine e neʻe i ka ʻomoʻana i ka insulin.

ʻLoe a me ke kākele

Lawe ʻia ia Diameride.

Lawe ʻia nā papa me ka ʻole o ka minamina, ka piha, me ka nui o ka wai (ma kahi o 100 ml). Ma hope o ka lawe ʻana i ka lāʻau lapaʻau, ʻaʻole ʻōlelo ʻia ka ʻaʻa ʻole ʻana.

Hoʻoholo ke kauka i ka hoʻoponopono regimen i hoʻokahi, ma muli o nā hopena o ka nānā pinepine ʻana o ka kaila glucose koko.

I ka hoʻomaka ʻana o ka pena, hoʻoluhi ʻia ka diamerid i ka 1 mg i kēlā me kēia lā. Ma hope o ka loaʻa ʻana o ka hopena therapeutic maikaʻi loa, e hōʻike ʻia kēia lāʻau e like me ka nui o ka mālama ʻana.

I nā hihia o ka nele o ka mālama glycemic, pono e neʻe lohi ka nui o kēlā me kēia lā (me nā laha o ka 1-2 mau pule) ma lalo o ka kiaʻi ʻana i ka nānā ʻana o ka glucose o ke koko i ka manawa 2, 3 a i ʻole 4 mg i kēlā me kēia lā. ʻO nā ʻoi aku kiʻekiʻe ʻoi aku ka hopena ma nā hihia kūʻokoʻa wale nō. Kūpono - 6 mg o kēlā me kēia lā.

ʻO ka manawa a me ka manawa o ka lawe ʻana i ka lāʻau lapaʻau e hoʻoholo ʻia e ke kauka. ʻO ka kumumana o ke noi o ka diamerid e noʻonoʻo i ke ʻano o ka mea maʻi. Pono ka ʻai ʻia o kēlā me kēia lā i kahi ma 1 mau manawa ma mua a i ʻole i ka wā o ka ʻaina kakahiaka a i ʻole ka kīʻaha mua.

Kuhi ʻia ʻo Diameride no ka maʻi lōʻihi, kahi e hana ʻia ma lalo o ka kaohi o ka glucose koko.

I nā hihia o ka nele o ka mana glycemic i nā maʻi e lawe ana i ka metformin, ʻoi paha ke kau hou aku nei ʻo Diameride.

ʻAʻole loli ka hopena o ka metformin; i ka hoʻomaka ʻana o ka ʻohi, e pono ke kuhikuhi ʻia o ka diamerid i ka palena liʻiliʻi, e hoʻonui ʻia ana a hiki i ka nui. Pono e hoʻokau ʻia ʻo ka lāʻau hoʻohui ma lalo o ka nānā mau ʻana o kahi loea.

Inā ʻaʻole hiki ke hoʻokō ʻia ka mālama glycemic i ka wā e lawe ai i ka nui o ka nui o Diameride e like me ka monotherapy, hiki ke kuhikuhi ʻia i ka insulin hou, i kuhikuhi ʻia i ka palena liʻiliʻi ma ka hoʻomaka ʻana o ka hopena. Inā pono, hiki i kahi hoʻonui lohi. Pono e hoʻokau ʻia ʻo ka lāʻau hoʻohui ma lalo o ka nānā mau ʻana o kahi loea.

Ke hoʻoneʻe nei i ka mea maʻi mai kekahi lāʻau lapaʻau hypoglycemic waha a Diameride, ʻo kāna ʻano laʻi mua i kēlā me kēia lā he 1 mg (ʻoiai ke neʻe ʻia ka mea maʻi mai ka nui o ka lāʻau ʻana i ka lāʻau hypoglycemic oral). Pono e hoʻonui ʻia i kekahi ʻoi aku ka nui o ka dosis Diameride e like me nā ʻōlelo aʻoaʻo ma luna nei. ʻO ka mea e pono ai, nā palena a me nā lōʻihi o ka hana a ka luna hypoglycemic i hoʻopili ʻia, e noʻonoʻo pono. I kekahi mau hihia, ʻoi aku ka wā e lawe ai i ka lāʻau hypoglycemic me ka hapalua ola, hiki ke hoʻopau ʻia i kahi manawa pōkole o nā lāʻau (i kekahi mau lā), kahi e kōkua no ke pale aku i ka hopena hoʻohui e hoʻonui i ka hiki o ka hypoglycemia.

Ke hana nei i ka inika insulin i nā poʻe maʻi me ka diabetes mellitus type 2, aʻo ka uku ʻana i ka maʻi a mālama i ka hana huna i ka ʻimi o ka pancreatic β-cells i nā hanana kūʻokoʻa, hiki ke loli ke ʻano o ka insulin e ka Diamerid (i ka hoʻomaka ʻana o ka hana ʻana, e hoʻohana ʻia nā ʻoka haʻahaʻa loa). Pono e lawe ʻia ka unuhi ʻana ma lalo o ka nānā ʻana o kahi loea.

Nā hopena hopena

• kumumanaʻo o ka ʻike: ʻike ʻia ka ʻike papale (ʻike ʻia, ma ke ʻano he kānāwai, i ka hoʻomaka ʻana o ka lāʻau, ma muli o kahi hoʻololi o ke kaohi o ka glucose i loko o ke koko),
• ka hana: ka hopena hypoglycemic (e hoʻomohala i ka manawa ma hope o ka lawe ʻana iā Diamerid a hiki ke hele mai i nā hoʻopiʻi hewa, ʻaʻole i maʻalahi ke kaohi ʻana, ke nānā nui ʻia ko lākou helehelena e nā mea kū hoʻokahi, ʻo ia hoʻi o ka meaʻai a me ka hopena i hoʻohana ʻia).
• hematopoietic ʻōnaehana: thrombocytopenia (i ka papa / kūpono / ikaika), leukopenia, granulocytopenia, erythrocytopenia, aplastic / hemolytic anemia, pancytopenia, agranulocytosis,
• ka pehu ʻōpala: hoʻomehana, nausea, hōʻoluʻolu / hōʻeha i ka epigastrium, ʻeha ma ka ʻōpū, ʻeha, hoʻokaʻawale (hōʻoli i ka lāʻau lapaʻau i nā hihia luhi loa), hoʻonui i ka hana o nā ate enzyme, jaundice, cholestasis, hepatitis (i kekahi manawa me ka hoʻomohala ʻana o ka palupalu o ka palaleka).
• nā hopena dermatological: i kekahi mau hihia, hope cutaneous porphyria, photosensitivity,
• nā maʻi kūlohelohe: urticaria (ma ke ʻano o ka ʻeha, ka ʻupena o ka ʻili, maʻa mau ia, akā hiki ke holomua, ka hele ʻana me ka pōkole o ka hanu, ka hāʻule ʻana o ke koko, a hiki i ka hoʻomohala ʻana o ka anaphylactic pīhoihoi, koi i ka mālama koke iā lākou), cross-allergy me nā sulfonamides ʻē aʻe. derivatives o sulfonylureas a i ʻole sulfonamides, allergic vasculitis,
• nā mea ʻē aʻe: i kekahi mau hihia - hyponatremia, asthenia, pilikia nui.

Nā ʻōlelo kikoʻī

Pono ka poʻe maʻi e mālama i ka regimen dosis i kuhikuhi ʻia. ʻAʻole hiki ke hoʻopaʻi ʻia ka hōʻole ʻia o ka wai hoʻokahi ma o ka ʻĀina ma mua o kahi ʻoihana kiʻekiʻe kiʻekiʻe.

ʻO ka hopena o ka hypoglycemia ma hope o ka lawe ʻana i ka 1 mg o ka diamerid ka mea hiki ke mālama i ka glycemia ma o kaʻaiʻai.

Ke loaʻa ka uku no ka maʻi diabetes type 2, ʻike ʻia ka hoʻonui ʻia ʻana o ka naʻau o ka insulin. I kēia mea, i ke ʻano o ka lāʻau, e hoʻemi paha ka pono no Diameride. I mea e hōʻalo ai i ka hoʻomohala ʻana o ka hypoglycemia, pono ʻoe e hoʻemi iki i ka hōʻemi a hōʻoki paha i ka mālama ʻana. Pono nō ka hoʻoponopono ʻana o ka dosis i nā hihia o nā loli i ke kaumaha o ka mea maʻi, kona ʻano, a i ʻole ke ʻano ʻia nā mea ʻē aʻe e hoʻonui ai i ka hopena o ka hyper- a i ʻole hypoglycemia.

No ka hoʻokō ʻana i ke koina o ka ʻai o ke koko a me ka hoʻokele maʻamau o ka lāʻau, pono ia e mālama i ka ʻai kūpono a hoʻokō i ka hoʻomaʻamaʻa kūlohelohe kūpono kūpono.

ʻO nā hōʻailona maʻi o ka hyperglycemia e loaʻa i ka makewai nui, ka hoʻonui ʻana i ka nui o ka urination, ʻili maloʻo a me ka waha maloʻo.

I nā pule mua o ka hoʻohana ʻana iā Diamerid, hiki ke hoʻonui ʻia ka nui o ka hypoglycemia (i kēia mau hihia, pono ka mālama pono ʻana i ke ʻano o ka mea maʻi). Inā ʻai ʻoe i ka manawa maʻamau a i ʻole kaʻai ʻana i nā meaʻai, hiki mai ka hypoglycemia.

ʻO nā mea nui i kaukaʻi ʻia i ka hoʻomaka ʻana o ka hypoglycemia:

• ka makemake ʻole / ka lawa ʻole (ʻoi aku hoʻi i ke au kahiko) o ka mea maʻi e hana pū me ke kauka,
• ka ʻai ʻai ʻana, me ka loli o ka meaʻai maʻamau, ka pōloli, ka 'ōpelē / pōʻino, kaʻai ʻana i ka ʻai,
• inu wai ʻona, keu me ka hoʻohui pū ʻana i nā meaʻai ʻaʻai,
• ka hoʻemi ʻana ma waena o ka hana kālai a me ka hana kino,
• hana hepatic maʻi i loko o ka papa kūlana koʻikoʻi,
• hemo i luna o ka diamerid,
• huakaʻi renal function,
• hoʻohui me kekahi mau lāʻau ʻē aʻe,
• kekahi mau maʻi uncompensated o ka ʻōnaehana endocrine e pili ana i ka metabolism kalehu, me ka thyroid dysfunction, adrenal insufficiency, a pituitary insufficiency.

Pono e hōʻike ʻia aku i ke kauka i ka noho ʻana / hele ʻana o nā mea o luna, a me nā hopena no ka hypoglycemia, i kēia mau hihia. Inā hele kēia mau mea, pono kahi koi / hoʻoponopono hoʻoponopono hou ʻia. Hana ʻia nā ʻano like ʻole i nā hihia o ka maʻi intercurrent a i ʻole e loli ke ʻano o ka noho ʻana o ka mea maʻi.

I nā poʻe maʻi ma waena, hiki i nā mea maʻi me ka neuropathy autonomic a i nā mea maʻi e loaʻa ana i ka hopena concomitant me ka guanethidine, beta-blockers, reserpine, clonidine, nā hōʻailona o ka hypoglycemia e hoʻomaʻemaʻe paha i waho a haʻalele paha.

I ka aneane āpau, hiki ke hoʻokuʻu koke ʻia ka hypoglycemia e ka hoʻokomo koke ʻana o nā calcium (kaʻaila a me ka glucose). I kēia mea, pono i ka mea maʻi e loaʻa ma ka 20 g o ka glucose (4 mau mea momona o ke kō). I ka mālamaʻana i ka hypoglycemia, ʻaʻohe mea momona e hoʻomaʻamaʻa maikaʻi.

ʻOiai ka pōmaikaʻi mua loa i ka pani ʻana i ka hypoglycemia, hiki ke ʻike ʻia ka hoʻomohala ʻana o kona hoʻomaha, ka mea e koi mau ana i ka mālama maʻamau o ke ʻano o ka mea maʻi. Ma ka hypoglycemia koʻikoʻi, koi nui ka mālama ʻana ma lalo o ka mālama ʻana o kekahi loea, a i kekahi manawa hoʻokipa.

I ka wā o ka papa hana, pono e mālama pono ʻia ka mālama ʻana i ka hana o ka puʻukū a me ke kiʻi koko peripheral (ma ke ʻano kūikawā, pili kēia i ka nui o nā platelets a me nā keʻena koko keʻokeʻo).

I nā kūlana koʻikoʻi (no ka laʻana, nā hōʻeha, nā hana hōʻeuʻeu, hui pū ʻia e nā maʻi maʻi ʻeha), pono paha e neʻe ka mea maʻi i ka insulin.

ʻAʻoheʻike i ka hoʻohana ʻana o ka diamerid i nā mea maʻi me ka hana o ka renal / hepatic functioning i nā hihia koʻikoʻi a i ʻole nā ​​mea maʻi i ka hemodialysis (hōʻike ʻia ka insulin).

I ka wā mālama, ʻo ka ʻike o ka glucose i loko o ke koko, a me ka paʻa ʻana o ka hemoglobin glycosylated.

ʻO kekahi mau hopena maikaʻiʻole (ma ke ʻano o ka hypoglycemia koʻikoʻi, nā loli koʻikoʻi i ke kiʻi o ke koko, ke ʻano maʻi kūlohelohe nui, ka huhū palupalu) ma lalo o nā kūlana e hiki ke hoʻoweliweli. I nā hihia hōʻeha nui a me ka maikaʻi ʻole, pono e hōʻike koke ka mea maʻi i ka loea e pili ana iā lākou. Mai hoʻomau e hoʻomau i ka lawe ʻana i ka lāʻau.

I ka hoʻomaka ʻana o ke papa, i ka wā e ke hoʻololi nei i kekahi lāʻau lapaʻau i ka lāʻau ʻē aʻe a i ʻole ke ʻano hanana ʻole o Diamerid, he ka emi ʻana o ka neʻe ʻana a me ka wikiwiki o ka huli ʻana o ka psychomotor ma muli o ka hyper- a hypoglycemia paha e kū nei, e pili ana i ka hiki ke hoʻokele i nā kaʻa. Pono nā mea maʻi e hana i nā pale e pale aku ai i kēia mau ʻano. ʻO nā mea maʻi i loaʻa ʻole / ua hōʻemi i ka nui o nā hōʻailona o ka mea hele mua i aʻo ʻia e hōʻole i ka lawe ʻana i nā kaʻa.

Inoa Kūʻai ʻole honua

ʻO ka inoa waiwai ʻole honua no kēia lāʻau lapaʻau ka glimepiride. Hōʻike ia i ka lāʻau lapaʻau ikaika. ʻO kēia ʻano he kolu o nā hanauna uʻi o ka olakoka sulfonylurea.

ʻO Diamerid kahi lāʻau lapaʻau i hoʻohanaʻia e hoʻohaʻahaʻa i ka glucose koko.

ʻO ke code o ka lāʻau lapaʻau e like me ka ATX (hoʻonaninani, ka therapeutic a me ka helu palaka) ʻo A10BB12. ʻO ia, ʻo kēia lāʻau lapaʻau ka mea hana e hoʻopili ai i ka hana a me ka hoʻoneʻe ʻana, i manaʻo ʻia e kāpae i ka maʻi maʻi, i manaʻo ʻia he ʻano hypoglycemic, kahi ʻano o ka sulfonylurea (glimepiride).

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

Ma ke kānāwai, ke hoʻoholo nei ka hopena o ka lāʻau e ka wahi e ʻike ʻia ana o ka glucose i loko o ke koko. ʻO ka maʻa haʻahaʻa e lawa ai i ka hoʻokūkū pono kūpono e pono e hoʻohana.

I ka wā o ka mālama ʻana, pono ia i ka hoʻoholo pinepine i ka neʻe o ka glucose i ke koko. Eia kekahi, ʻoi aku ka mālama pinepine ʻana i nā pae hemoglobin glycosylated.

Ke hana ʻole nei i ka lāʻau, no ka laʻana, ka hemo ʻana i ka hopena hou aʻe, ʻaʻole pono e hoʻohui ʻia e ka nui o ke ʻano kiʻekiʻe o ke ʻano kiʻekiʻe. ʻO ka hana a ka mea maʻi ma kahi o nā hewa i ka wā e lawe ai i ka lāʻau lapaʻau (ʻoiai, i ka wā e keʻe nei i ka hopena hou aʻe a i ʻole ke kala ʻana i ka ʻai) a i nā kūlana i ʻole i hiki ʻole ke lawe ʻia i ka lāʻau lapaʻau e kūkā mau ʻia e ka mea maʻi

Lawe ʻia ka Diameride me ka honi ʻole, holoi ʻia me ka nui o ka wai (e like me 0,5 mau kī).

ʻO ka maʻa mua loa he 1 mg o ka glimepiride hoʻokahi i ka lā. Inā pono, hiki ke hoʻonui ʻia ka nui o ka lā i kēlā me kēia lā (ma waena o 1-2 mau pule). Kuhi ʻia ia e hoʻomau ʻia ka piʻi ʻana o ka maʻi ma lalo o ka mālama pono ʻana i ka hoʻoliʻi o ka glucose koko a e like me ke ʻano o ka hoʻonui manawa haʻahaʻa: 1 mg - 2 mg - 3 mg - 4 mg - 6 mg (- 8 mg).

Ma ka pāʻālua ka nui o nā maʻi i ka maʻi mellitus e hoʻomalu ʻia i ka maʻi maʻamau: ʻo ka maʻamau ka nui o ka pākiki i kēlā me kēia lā i nā poʻe maʻi me ka maʻi diabetes mellitus ka maʻi ma kahi o ka nui o ka nui o ka maʻi mellitus. ʻOi aku ka momona o kahi lā ma mua o 6 mg ʻoi aku ka maikaʻi ma loko o kahi helu liʻiliʻi o nā maʻi.

ʻO ka manawa kūpono a me ke kaʻana o nā doses i ka lā āpau i hoʻoholo ʻia e ke kauka, ma muli o ke ʻano o ka mea maʻi ma ka manawa manawa (kākau manawa, ka nui o nā hana pilikino).

ʻO ka maʻamau, hoʻokahi ka nui o ka lāʻau lapaʻau i ka lā i lawa. Ua hoʻomaopopo ʻia ma kēia hihia, e lawe koke ʻia ka papa holoʻokoʻa o ka lāʻau ma mua o ka ʻaina kakahiaka piha, a i ʻole ʻaʻole i lawe ʻia i kēlā manawa, ma mua o ka pāʻina mua.

He mea nui loa ia e hoʻokaʻawale i ka ʻai ma hope o ka lawe ʻana i ka lāʻau lapaʻau.

No ka mea e pili ana i ka hoʻokele metabolic hoʻomaikaʻi me ka hoʻonui ʻana i ka naʻau o ka insulin, pono ke emi ka nui o ka glimepiride i ka wā mālama. I mea e pale ai i ka hoʻomohala ʻana o ka hypoglycemia, pono ia e hōʻemi i ka manawa kūpono a i ʻole ke inu i ka lāʻau lapaʻau.

Pono e koi ʻia nā kūlana e hoʻoponopono ʻia ai i ka lāʻau lapaʻau.

- hōʻemi i ke kaupaona kino o ka mea maʻi,

- ka loli ma ke ʻano o ka mea maʻi (loli i kaʻai, ka manawa ʻai, ka nui o ka hana kino),

- ka puka mai o nā mea ʻē aʻe e alakaʻi i kahi predisposition i ka hoʻomohala ʻana o ka hypoglycemia aiʻole hyperglycemia.

Hoʻololi pinepine ʻia ka hoʻomaʻamaʻa Glimepiride no ka manawa lōʻihi.

Hoʻololi i ka mea maʻi i ka lawe ʻana i kekahi lāʻau lapaʻau hypoglycemic waha e lawe iā Diamerid: ʻaʻohe pilina pololei ma waena o nā pona o ka glimepiride a me nā mea āpau hypoglycemic no ka hoʻokō waha.Ke hoʻololi ʻia kahi laikini hypoglycemic e pili ana i ka hoʻopale waha me ka glimepiride, ke kuhikuhi ʻia nei ke ʻano o ke kaʻina hana no ke kuhikuhi ʻana i ka ʻano like me ka hoʻomaka mua ʻana, ʻo ia ka mea e hoʻomaka ana ka mālama ʻana me kahi maʻi pā mua o 1 mg (ʻoiai ke neʻe ka mea maʻi i ka glimepiride me ka nui loa kekahi lāʻau lapaʻau hypoglycemic hou no ka hoʻokele waha). Pono e hoʻonui ʻia ka hoʻonui ʻana i kēlā me kēia mahele, e noʻonoʻo ana i ka pane i ka glimepiride, e like me nā ʻōlelo o luna.

Pono e mālama i ka ikaika a me ka lōʻihi o ka hopena o ka ʻaihue hypoglycemic ma mua no ka hoʻokō waha. ʻO ka ʻaina o ka mālama ʻia e pono ai e pale i ka hoʻopiʻi ʻana i nā hopena e hoʻonui ai i ka hopena o ka hypoglycemia.

Hoʻohana me ka hui pū me ka metformin

I ka poʻe maʻi me ka maʻi ʻohi o ka maʻi mellitus, i ka wā e lawe ai i ka nui o nā lā nui o kēlā me kēia glimepiride a i ke metformin, e mālama ʻia ai ka hui ʻana o kēia mau lāʻau ʻelua. Ma kēia hihia, ke hoʻomau nei ka mālama mua me bohala glimepiride a i ʻike paha i ka pae hoʻokō like, a hoʻomaka ʻia ka nui o ka metformin a i ʻole glimepiride me kahi haʻahaʻa haʻahaʻa, ʻo ia ka titrated ma muli o ka pae hoʻokele o ka hoʻokele metabolic a hiki i ka pae nui loa o kēlā me kēia lā. Pono e hoʻoulu ʻia ʻo ka lāʻau lapaʻau ma lalo o ka nānā kiaʻi olakino.

Hoʻohana me ka insulin

I nā mea maʻi me ka maʻi mellitus e lawa ʻole ʻia, e hāʻawi ʻia ka insulin i ka manawa like i ka wā e lawe ai i ka nui o nā lā he nui o glimepiride. I kēia hihia, ʻaʻole i loli iki ka hopena hope o ka glimepiride i ʻōlelo ʻia i ka mea maʻi. I kēia hihia, hoʻomaka ka mālama ʻana i ka insulin me nā hōʻemi haʻahaʻa liʻiliʻi, e hoʻonui i lalo ma lalo o ka kaohi o ke kaʻe o ka glucose i loko o ke koko. Hoʻohālikelike ka mālama ʻana i ka mālama ʻana i ka lāʻau lapaʻau.

Hoʻohana i ka poʻe maʻi me ka hiki ʻole o ka pale

He palena iki nā ʻikepili e pili ana i ka hoʻohana ʻana o ka diamerid i nā maʻi me ka hiki ʻole o ka renal. ʻO nā mea maʻi me ka hana renal impaired i ʻoi aku ka naʻau i ka hopena hypoglycemic of glimepiride.

Hoʻohana i ka poʻe maʻi me ka hiki ʻole o ka ate

Loaʻa kahi paʻa ma ka hoʻohana ʻana i ka lāʻau lapaʻau no ka hoʻopau ʻana o ka ate.

Hoʻohana i nā keiki

ʻAʻole lawa i ka ʻikepili ma ka hoʻohana ʻana i nā keiki.

E hoʻokuʻu i nā palapala a me ka ʻano

Loaʻa ka lāʻau lapaʻau i nā papa. ʻO ke ʻano o nā pā pōhaku he cylinder palalike me kahi bevel. Kūpaʻa ʻia ke kala i ka nui o ka mea hana i loko o ka papa; i ʻeleʻele a ʻulaʻula paha paha.

Aia nā papa i nā 1, 2, 3 mg a i ʻole 4 mg o ka hoʻoulu ola.

ʻO nā mea kū'ē:: lactose monohydrate, magnesium stearate, povidone, microcrystalline cellulose, poloxamer, sodium croscarmellose, ʻeleʻele.

Hoʻokahi i hoʻokahi pahu i 3 pōlani, kēlā me kēia o 10 mau pcs.

Ka hana lāʻau lapaʻau

Loaʻa i kēia lāʻau lapaʻa kahi hopena hypoglycemic. ʻO ka hana a ka lāʻau lapaʻau e pili ana i ka hoʻoulu ʻana i ka hana o ka insulin e nā cell beta o nā mokupuni pancreatic o Langerhans, a me ka hoʻonui ʻana i ka paʻakui o nā ʻāpana ʻāhewa i ka hormone a hoʻonui i ka nui o nā protein transporter glucose i loko o ke koko. Ka hana ma ka kiko pancreatic, hoʻomākaʻi ʻia ka lāʻau i ka depolarization a me ka wehe ʻana o nā kaola e hilinaʻi nei i nā kaila, ma muli o ka mea e hoʻokau nei ka hoʻonā.

Hoʻemi ia i ka helu o ka gluconeogenesis i loko o ka ate ma muli o ka hoʻopaʻa ʻana i nā enzyme koʻikoʻi, no laila he hopena hypoglycemic.

He hopena ka lāʻau i ka hōʻiliʻili platelet, e hōʻemi ana ia. Ke pale nei i ka cyclooxygenase, ke kāohi nei i ka oxidation o ka arachidonic acid, he hopena antiioxidant, e hōʻemi ana i ka helu o ka lipid peroxidation.

Lapaʻau lāʻau

Me ka hoʻohana maʻamau, ma 4 mg pākahi i kēlā me kēia lā, ʻike ʻia ka nui loa o ka lāʻau ma ke koko ua mau hola 2-3 ma hope o ka hoʻokō ʻana. A hiki i ka 99% o ka waiwai e hoʻopili ai i nā protein serum.

ʻO ka hapalua kahi ola he 5-8 mau hola, ua hoʻihoʻi ʻia ka waiwai i loko o kahi ʻano metala, ʻaʻole ʻohi i loko o ke kino. Hele ma ka pletenta a hala i ka waiū umauma.

Pehea e lawe ai i ka diamerid?

Ke lawe nei i ka lāʻau lapaʻau, pono mau ke kauka i ka pae o ka glucose i ke koko. Hoʻoholo ka mea hoʻolālā loea i ke ʻano o ka glucose i ke koko, ʻo ia hoʻi ma hope o ka lawe ʻana i ka lāʻau. Hoʻohana ʻia ka lāʻau liʻiliʻi liʻiliʻi, me ia ka hopena e pono ai.

Loaʻa ka lāʻau lapaʻau i nā papa. ʻO ke ʻano o nā pā pōhaku he cylinder palalike me kahi bevel.

Me ka maʻi diabetes

ʻO ka maʻa mua he 1 mg i kēlā me kēia lā. Me kahi papa o 1-2 mau pule, e hoʻonui ai ke kauka i ke ʻano, e koho ana i ka mea e pono ai. ʻAʻole hiki iā ʻoe iho, me ka ʻole o ka ʻimi ʻana i ke kauka, e hoʻomaka i ka lāʻau a hoʻololi paha i ka ʻōlelo i kauoha ʻia, no ka mea he koikoi ikaika, e hoʻohana ʻia ka hopena maikaʻi ʻole.

Me ka maʻi maʻamau i hoʻopaʻa ʻia, ʻo ka nui o ka lāʻau lapaʻau i kēlā me kēia lā he 1-4 mg, ʻoi aku ka nui o nā ʻike kiʻekiʻe ma muli o ka hana i hoʻohana ʻia no ka helu liʻiliʻi o nā kānaka wale nō.

Ma hope o ka lawe ʻana i ka lāʻau lapaʻau, pono ʻoe e lele i ka ʻai ʻana, ka mea e lohi. He lōʻihi ke nānā ʻana.

Hoʻolako ʻia ʻo Diameride no ka mellitus type type 2, inā he mea lapaʻau me ka lāʻau haʻahaʻa-haʻahaʻa a me ka hana kino maʻamau e hāʻawi aku i ka hopena i makemake ʻia.

Hoʻopilikia i ka hiki ke mālama i nā mīkini

Hoʻomaʻamaʻa ka lāʻau lapaʻau i ka hiki ke mālama i nā hana ma muli o ka hoʻolālā ʻana o ka hypoglycemia, ka mea i hele pū ʻia e ka emi ʻana o ka neʻe, ka hana mau a me ka hiamoe. ʻO ka hiki ke hana i nā hana e koi ai i ka paʻa mau o ka nānā ʻana, me ke kaʻa o ka ʻimi ʻana, ua hoʻemi ʻia.

Hoʻohana i ka wā kahiko

I ka wā ʻelemakule, pinepine pinepine kahi kanaka i ke kamaʻilio wehe ʻana me kāna kauka, no ka mea hiki ʻole i ke kauka ke ʻike i ke ʻano o ka mea maʻi ma hope o ka lawe ʻana i ka lāʻau lapaʻau a hoʻoponopono i kahi ʻano, ʻike ʻino ʻia i ka hopena o ka lāʻau a me ke ʻano o ka mea maʻi. No laila, pono e ʻike ʻo ka mea maʻi i ke kauka e pili ana i nā loli āpau o ka moku'āina, me ka maopopo he mea pono kēia i mea mua no ia iho.

Hoʻohana i ka wā hāpai a me ka lactation

I ka wā hāpai a i ka wā o ka hānai, ua contraindicated ka lāʻau lapaʻau ma muli o kona hiki ke komo i ka pā plental a excreted i loko o ka waiū umauma, kahi e hiki ai ke hōʻeha i ka kino o kahi pēpē. No laila, he wahine i lawe i kēia lāʻau lapaʻau ma mua o ka lawe ʻana i ka hoʻohālikelike ʻana, hoʻāla ʻia i ka mālama ʻana i ka insulin.

I ka wā hāpai a ʻo ka umauma, ua contraindicated ka lāʻau lapaʻau

Ka pāʻana o ka diamerid

Ma kahi o kahi overdose, ua nānā ʻia ka hypoglycemia, ka mea i hele pū ʻia e ke poʻo, ka manaʻo o ka nāwaliwali, hoʻonui nui loa, ke kāʻoki ʻia, ka tachycardia, ka manaʻo o ka makaʻu a me ke kaumaha. Inā hele ʻoe i kēia mau ʻōuli, pono ʻoe e lawe i kahi lawelawe o nā kalapona wikiwiki, no ka laʻana, e ʻai i kahi ʻāpana o ke kō. I ka hihia o ka overdose o ka lāʻau, pono ia e holoi i ka ʻōpū a hoʻonāukiuki paha. A hiki i ka hiki ʻana i kahi kūlana paʻa, pono ke maʻi ma lalo o ka mālama kia olakino, no laila inā i loaʻa pinepine ka glucose, hiki i ke kauka ke kōkua.

Hoʻopili pū me nā lāʻau ʻē aʻe

I ka wā e hoʻohana ai i ka lāʻau lapaʻau me nā lāʻau ʻē aʻe, hiki iā ia ke hoʻonāukiuki a hoʻoikaika paha i kāna hana, a me ke ʻano o ka hoʻololi ʻana i nā hana o kekahi mea ʻē aʻe, no laila he mea nui e hoʻomaopopo i ke kauka e pili ana i nā lāʻau i hoʻohanaʻia. Ma ke ʻano he:

1. Me ka hoʻomohala ʻana o ka glimepiride a me ka insulin, e hiki ai i nā lawehala hypoglycemic hou, nā derivatives Coumarin, glucocorticoids, metformin, hormones sex, angiotensin-hoʻohui i nā enzyme inhibitors, fluoxetine, etc., a hiki ke ʻano hypoglycemia koʻikoʻi.
2. Hiki i ka Glimepiride ke hōʻoki a hoʻomaikaʻi paha i ka hopena o nā derivatives o Coumarin - nā mea hoʻohui anticoagulant.
3. ʻO nā Barbiturates, laxatives, T3, T4, glucagon hiki ke hoʻonāwaliwali i ka hopena o ka lāʻau lapaʻau, e hōʻemi ana i ka hopena o ka mālama ʻana.
4. Hiki i nā H2 histamine receptor blockers ke hoʻololi i ka hopena o ka glimepiride.

Me ka hoʻomohala pinepine ʻana o ka glimepiride a me ka insulin, nā mea'ē aʻe nā loea hypoglycemic maʻi, hiki i ka hoʻomohala ʻana o ka hypoglycemia koʻikoʻi.

Hoʻolaha ka waipuna

Hiki i hoʻokahi dosis o ka waiʻona a i kāna hoʻohana mauʻana paha ke hoʻololi i ka hana o ka lāʻau lapaʻau, hoʻonui a hoʻoemi paha.

ʻO nā analogues nā hui āpau i loaʻa i ka glimepiride ma ke ʻano he mea ikaika. ʻO kēia mau lāʻau lapaʻau e like me:

1. Amaril. He lāʻau lapaʻau kēia ʻo Siemania, kēlā me kēia papa i loaʻa i kahi kahe o 1, 2, 3 a i ʻole 4 mg. Hoʻoulu: Kelemānia.
2. Canon Glimepiride, Loaʻa i nā poki o ka 2 a i ʻole 4 mg. Hoʻoulu: Lūkia.
3. Glimepiride Teva. Loaʻa i nā dosia o 1, 2 a i ʻole 3 mg. Hoʻoulu: Croatia.

ʻO ka maʻi maʻi diabetes he hypoglycemic lāʻau, ke like ka hopena hypoglycemic like, akā ʻo kāna hana ikaika he mea no ka sulfonylurea o ka lua o ka hanauna.

ʻO Amaryl kahi hoʻohālikelike o Diamerid. He lāʻau lapaʻau kēia ʻo Siemania, kēlā me kēia papa i loaʻa i kahi kahe o 1, 2, 3 a i ʻole 4 mg.

Hoike ʻia no Diamerida

Ma mua o ka hoʻohana ʻana i ka lāʻau lapaʻau, pono ʻoe e kamaʻilio e pili ana i nā loiloi e pili ana iā ia.

Starichenko V. K: "He mea maikaʻi nā lāʻau lapaʻau nei no ka hoʻopau ʻana i nā maʻi maʻi ʻo ʻAmelika 2. ʻae ʻia ia e hoʻohana me ka insulin a i ʻole ia monotherapy. Hiki wale i ke kauka ke kau a hoʻoponopono i ka maʻi."

ʻO Vasilyeva O. S .: "ʻO ka lāʻau lapaʻau e hōʻemi i ka pae o ka glucose i ke koko, ke pale aku i nā hopena maikaʻi ʻole o ka maʻi maʻi. ʻO ke ʻano loea wale nō e kākau i ka lāʻau a hoʻoholo i ka regimen lapaʻau."

ʻO Galina: "Hōʻā ke piʻi i ke kō o ke koko, kahi lāʻau lapaʻau me ka glimepiride hoʻōla i kauoha ʻia. Ua ʻoluʻolu nā papa, ʻele maikaʻi, lawe i kēlā me kēia lā ma mua o ka ʻaina. He ʻano nā glucose koko, nā hemahema ʻole o ka maʻi diabetes."

Hoʻohui nūhou

Me ka hoʻohana pū ʻana o Diameride me kekahi mau lāʻau lapaʻau / mau mea, hiki ke ulu ʻia nā hopena aʻe (e koi ʻia ka ʻōlelo lapaʻau ma mua o ke kuhikuhi ʻana i kekahi lāʻau lapaʻau):

• acetazolamide, barbiturates, glucocorticosteroids, diazoxide, saluretics, thiazide diuretics, epinephrine a me nā mea hou e nāathathomimetic, glucagon, laxatives (me ka hoʻohana ʻana i ka manawa lōʻihi), ka pāʻana o ka acid nikotinic, waikawa nikotinic (ma nā helu koʻikoʻi), estrogens, protazibotaota , phenytoin, rifampicin, hormone thyroid, paʻakai lithium: nāwaliwali i ka hopena hypoglycemic a, ma muli o ka hoʻonui ʻana aʻe o ka glucose i loko o ke koko,
• insulina, metformin 'ole' ē aʻe waha hypoglycemic Agena, angiotensin hoʻololi ''ūhū nā mea kūpale, allopurinol, anabolic steroid a me kane ke keka hormones, chloramphenicol, coumarin nā mea loaʻa, cyclophosphamide, trofosfamide a me ka ifosfamide fenfluramine, fibrates, fluoxetine, sympatholytic (guanethidine), monoamine oxidase nā mea kūpale, miconazole, pentoxifylline (me ka mālama makua makua i nā kaila kiʻekiʻe), phenylbutazone, azapropazone, oxyphenbutazone, probenecid, quinolone antibiotics, salicylates a me aminosalicylic acid, s Ulfinpyrazones, kekahi sulfonamides lohi ka lōʻihi, tetracyclines, tritokvalin, fluconazole: hoʻonui i ka hopena hypoglycemic a, ma muli o ia, i ka hopena o ka hypoglycemia,
• reserpine, clonidine, N blockers₂-histamine ʻāpono: potentiation / nāwaliwali o ka hana hypoglycemic o ka diamerid,
• nā mea kanu e pale ai i ka hematopoiesis pumehana o ka iwi: he hoʻonui i loko o ka hopena noʻu myelosuppression,
• Couivin derivatives: hoʻoikaika / nawaliwali o kā lākou hana,
• beta-blockers, clonidine, reserpine, guanethidine: nāwaliwali a i ʻole nā ​​hōʻailona o ka hōʻailona o ka hypoglycemia,
• inu wai (maʻi / hoʻohana hoʻokahi): hoʻonui / palupalu i ka hana hypoglycemic hana o ka diamerid.

ʻO nā hōʻuluʻulu o ka Diameride nā: Glimepiride, Amaryl, Glemauno, Glime, Glemaz, Meglimid, Glymedeks a me nā mea'ē aʻe.

ʻŌpū a me ka lactation

Contlimicated ʻo Glimepiride i ka wā hāpai. I ka hihia o kahi hapai i hoʻolālā ʻia a i ka hoʻomaka ʻana o ka hāpai ʻana, pono i kahi wahine e hoʻoneʻe i ka ʻomo insulin.

No ka mea No ka hele ʻia ka glimepiride i ka waiū umauma, ʻaʻole pono ke kuhikuhi ʻia i ka wā lactation. I kēia hihia, pono ia e hoʻololi i ka hoʻololi ʻana i ka insulin a i ʻole e pau i ka ʻōpū.

E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana a me ka pōpoki

Ka ʻokoʻa o ka glimepiride i kēia mau papa i ʻokoʻa: 1, 2, 3 a i ʻole 4 mg. Eia kekahi, ua kau ʻia nā mea i laila:

• mikuleka
• konekena stearate,
• sodium polio
• pauku cellulose,
• nā vali.

He mau papaʻi, ʻehā paha kēia mau papa, ʻili ʻia i loko o kahi pua (3 a 6 paha) o 5 a 10 mau ʻāpana paha.

Nā ʻōkuhi no ka hoʻohana

Kuhi ʻia ka dosage e kekahi loea e pili ana i ka ʻikepili o nā hualoaʻa a me nā pono kanaka o ke kino.

Pono e lawe ʻia ma kahi ʻōpū ʻole, ma mua o ka ʻai ʻana, inu i ka wai o ka nui a ʻole ʻōiwi. ʻO ka ma mua mua he 1 mg hoʻokahi i kēlā me kēia lā. ʻOi aku, ma hope o 1-2 mau pule, hiki ke hoʻonui ʻia. ʻO ka palena kiʻekiʻe loa o kēlā me kēia lā he 6 mg.

Hoʻohālikelike me nā kikowaena

Nui a i nā lāʻau lapaʻau e like me nā mea i hōʻike ʻia. Maikaʻi e hoʻomanaʻo maikaʻi iā lākou i kā lākou mau mea a hoʻohālikelike i ka hana.

I Ka Kūʻai Diabeton. ʻO kēia nā papa i loaʻa ka gliclazide. Hoʻohui i ka hui "Servier", Farani. ʻO ke kumukūʻai o ka kāpena he 300 rubles a ma luna. ʻO kēia ka mea hoʻohālikelike e pili kokoke ana i nā waiwai. He maʻamau nā contraindications, ʻaʻole i manaʻo ʻia no nā ʻelemakule.

Amaril. ʻO ke kumukūʻai mai 300 a 1000 mau rubles no ka pālahalaha (30 mau ʻāpana). ʻOihana kāpili - Sanofi Aventis, Farani. ʻO kēia hui hui hoʻohui e pili ana i ka glimepiride a me ka metformin. Mahalo i ka hui pū ʻana o nā mea e hana wikiwiki ai a alakaʻi hou. He maʻi nā contraindications, he nui nā hopena kūpono.

NovoNorm. Ke ʻano lāʻau lapaʻau ka repaglinide. ʻEkolu mau ʻano o ka hoʻokuʻu ʻana, ma muli o ka hapa o ka mea ikaika. Hoʻomaka ke kumukūʻai ma nā 180 rubles no ka pālahalaha. ʻO ka mea hana - "Novo Nordisk", Denemaka. He mea kūpono kēia mea kūpono, kūpono, akā no ka loaʻa i nā helu contraindications. ʻAʻole kūpono no nā keiki, nā makua a me nā wahine hāpai.

Glimepiride. Kūleʻa - mai 140 a 390 mau rubles. ʻO ke kūpaʻa ʻoihana kūloko home, ʻo ia hoʻi i hana ʻia e ka hui ʻo Lūkia Vertex. ʻO ka māhele nui he glimepiride. Aia ʻelima mau ʻano ma ka mākeke me nā ʻano like ʻole o ka hana ikaika. Loaʻa iā ia kahi hopena like, nā like like nā contraindications. E hoʻohana me ka akahele no ka ʻelemakule.

Maninil. Ke loaʻa nei ka lāʻau lapaʻau i ka glibenclamide. Hoʻopuka i ka hui "Berlin Chemie", Kelemānia. Ke kumukūʻai haʻahaʻa - 120 mau rubles no nā papa 120. ʻO kēia ka analogue ka palena loa, ma nā ʻōlelo a me ka loaʻa. Nā like hoʻohālike.

Ua hoʻoholo ke kauka i ka mea maikaʻi loa no ka mea maʻi a hoʻokaʻawale i kekahi lāʻau lapaʻau. Ua papa ʻia ka lāʻau lapaʻau pilikino!

Loaʻa nā manaʻo o nā maʻi maʻi me ka ʻike ma ka lāʻau lapaʻau. Kuhi ka poʻe i ka pono o ka lāʻau lapaʻau, kahi helu liʻiliʻi. No kekahi, ʻaʻole kūpono ka hoʻoponopono.

Olga: "Ua lōʻihi wau i ke nānā ʻana i ka maʻi maʻi. Ua hoʻāʻo wau i nā paila he nui, ua kū wau i Diamerida. Hoʻohana wau i ka hui pū me Metformin, makemake nui wau i ka hopena o ka lāʻau. Maʻalahi ke gula, mai hopohopo i nā "ʻaoʻao." A ʻo ka mea nui loa, ua kūʻai paʻa ʻia ma nā wahi kūʻai. ”

Daria: “Ua lawe au iā Diameride i ʻelua mahina, ʻaʻole i loli ka hilo. Ua ʻōlelo ke kauka ʻaʻole he kūpono ia no kaʻu hihia, a kuhikuhi hoʻi i kekahi lāʻau lapaʻau. "

Oleg: “Ua kuhikuhi mai ke kauka iaʻu i kēia mau pā i kēia mau mahina i hala aku nei. Ua hoʻomau ke kūlana. ʻAʻole hopohopo nā fluctuations Sugar; maikaʻi ke olakino maikaʻi.He meaʻoluʻolu loa ia kēia lāʻau lapaʻau o ka hana kaiāulu, ma muli o nā waiwai a me ka maikaʻi ka maikaʻi ʻole ma mua o nā analogues haole. A no ke aha e pau ai inā loaʻa ka manawa i ka mālama ʻia me ka ʻoi aku kahi kūpono me ka hopena like a ʻoi aku ka maikaʻi. "

Elena: "He maʻi diabetes kaʻuehana 2. ʻO ka ʻai wale nō ua pau i ka kōkua, no laila ua koho ka endocrinologist iā Diamerid, i ʻōlelo ai he kanaka Lūkini ka hana, kūpono i ka maikaʻi. A ua hana ʻo ia iaʻu ma ʻekolu mahina i kēia manawa. He mea maʻalahi ia e lawe i hoʻokahi papa i kēlā me kēia lā, a lōʻihi ka hopena. ʻAʻole kime ka Sugar, ʻaʻole hele mai ka hypoglycemia, kahi mea ʻoluʻolu loa. E hoʻomau mau ʻia aku au e ka maʻi hānai ʻia e ia. "

Hoʻohālikelike

I ka hoʻoholo ʻana e nā loiloi a me nā waiwai i wehewehe ʻia o ka lāʻau lapaʻau, kū maikaʻi loa. Ua hoʻomaopopo ʻia he mahalo ka nui o ka helu kumukūʻai kumukūʻai, a ʻo ke kūkulu hale ʻokoʻa ʻaʻole ia he minus o ka lāʻau lapaʻau. ʻO ka maʻi Diabetics, a me nā mea loea, e hoʻomaopopo he maikaʻi ʻo Diamerid i ka monotherapy a i pū pū me nā lāʻau ʻē aʻe.

Nā kuleana a me nā kūlana e waiho ai

Pono ke mālama i ka lāʻau ma waho o ka hiki ʻana mai o nā keiki, maloʻo, palekana mai ka mālamalama, ma kahi wahi ma kahi wela ʻaʻole eʻoi aku ma mua o 25 ° C. ʻO 2 mau makahiki kahi ola.

- Kuhi 2 diabetes mellitus me ka hana ʻole o ka meaʻai a me ka hana kino mua.

Inā ʻaʻole maikaʻi ka monotherapy me glimepiride, hiki ke hoʻohana ʻia e like me kahi ʻāpana o ka hui pū ʻana me ka metformin a i ʻole insulin.