Vipidia 25 mg

Vipidia (nā papa) Rating: 177

Mea Hana: No ka huahua
Kuhi puka:

• ʻLelo. 12.5 mg, 28 pcs., Kumukūʻai mai 973 mau rubles
• ʻLelo. 25 mg, 28 pcs., Kumukūʻai mai 1282 mau rubles

ʻO nā kumukūʻai Vipidia ma nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Vipidia he māpana hypoglycemic i nā papa me alogliptin. Hāʻawi i kahi hōʻemi i ka hemoglobin glycosylated a me ka glucose. Ua hōʻike ʻia ma ka hihia o ka maʻi mellitus type 2 i ke ʻano o ka monotherapy, a me ka hoʻohui pū ʻana me nā mea hana hypoglycemic ʻē aʻe. ʻO ka maʻa loa ka 25 mg / lā, lawe ʻia ma kahi o ka meaʻai. Contraindicated ma ka maʻi ketoacidosis maʻi, type 1 diabetes mellitus, hōʻeha nui o ka naʻau puʻuwai, nā māla a me ka puʻuwai. ʻO nā hopena ʻaoʻao ka hilahila o ka hōʻeha, ka ʻeha i ka epigastrium, nā wikiwiki, nā maʻi lēʻeha o nā kino ENT. ʻAʻole maona ʻia nā keiki ma lalo o 18 mau makahiki a me nā wāhine hāpai wahine ma muli o ka nele o ka ʻike ma ka noi.

Nā kūmole o ka lāʻau Vipidia

ʻOi like ka analogue mai ka 863 mau rubles.

Mea Hana: Merck Sante SAA.S. (Palani)
Kuhi puka:

• Nā papa 500 mg, 30 pcs., Kumukūʻai mai 110 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai Glucophage i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO ka lāʻau Farani no ka mālamaʻana i nā maʻi maʻi 2. Kuhi i nā papa i loaʻa mai 500 a 1000 mg o ka metformin ka mea hana hoʻokahi. Aia kekahi mau contraindications, no laila, ma mua o ka lawe ʻana i Glucofage, pono e kūkā me kahi loea.

ʻOi like ka analogi mai ka 182 mau rubles.

Mea Hana: Novartis (Switzerland)
Kuhi puka:

• Nā Papa 50 mg, 28 pcs., Kumukūʻai mai 791 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai Galvus i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Galvus kahi papa papa no ka mālama ʻana i ka maʻi mellitus type 2 e pili ana i ka vildagliptin i loko o kahi waihona o 50 mg. Hiki ke hoʻohālikelike ʻia e like me monotherapy a ma ke ʻano o ka hui hoʻohui ʻana i ka hihia o ka maikaʻi o ka meaʻai a me ka hana.

ʻOi like ka analogi mai ka 795 mau rubles.

Mea Hana: Hemofarm A.D. (Serbia)
Kuhi puka:

• ʻLelo. 500 mg, 60 pcs., Kumukūʻai mai 178 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai Metformin i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO ka Metformin kahi lāʻau lapaʻau hypoglycemic Serbian no ka hoʻohana kūloko. ʻO ka hoʻonohonohoʻana o nā papa i loko o ka waihona hana ikaika o ka inoa like i loko o kahi waihona o 500 a 850 mg paha. Ua kuhikuhi ʻia no ka mālama ʻana i ka maʻi maʻamau ʻo 2 (i nā pākeke), ʻo ia hoʻi i nā maʻi me ka hiʻona.

Ua ʻoi aku ka mea kūʻai ma ka analogue mai 799 mau rubles.

Mea Hana: Ioana Maoli (USA)
Kuhi puka:

• Nā papa ʻaina 5 mg, 30 pcs., Kumukūʻai mai 1772 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai no Onglisa i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Onglisa kahi lāʻau lapaʻau ʻAmelika no ka mālamaʻana i ka maʻi mellitus type 2 e pili ana i ka saxagliptin i loko o kahi maʻi o 2.5 a i ʻole 5 mg. Ua hoʻohālikelike ʻia i ka hoʻohui ʻana o ke kino a me ka meaʻai e hoʻomaikaʻi ai i ka mana glycemic.

Ua ʻoi aku ka uku o ka analogue mai ka 1236 mau rubles.

Mea Hana: Merck Sharp a me Dome (USA)
Kuhi puka:

• Nā Papa 100 mg, 28 pcs., Kumukūʻai mai 2209 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai no Januvia i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Lāvia kekahi lāʻau lapaʻau ʻAmelika no ka maʻi maʻi. ʻO ka papa hana: sitagliptin (ma ke ʻano o ka phosphate monohydrate) 100 mg. Hiki ke hoʻohana i ka hoʻohui i ka hana kino a me ka meaʻai e mālama i ke kō koko.

Ua ʻoi aku ka uku o ka analogue mai ka 675 rubles.

Mea Hana: Beringer Ingelheim (Austria)
Kuhi puka:

• Nā papa ʻaina 5 mg, 30 pcs., Kumukūʻai mai 1648 mau rubles
• Nā Papa 1000 mg, 30 pcs., Kumukūʻai mai 185 mau rubles

ʻO nā kumukūʻai no Trazhenta i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Trazhenta - kahi lāʻau lapaʻau Austrian i manaʻo ʻia no ka mālama ʻana i ka maʻi mellitus type 2, hiki ke kuhikuhi ʻia e like me ka mono- a ma ke ʻano o ka hui pū ʻana. ʻO ka mea hana kūpono i ka hoʻopili hui ʻo linagliptin i loko o kahi waihona o 5 mg. ʻAʻole i kuhikuhi ʻia ka Trazenta no ka maʻi type 1, i ka wā hāpai, lactation, me nā keiki ma lalo o ka 18 mau makahiki o ka makahiki.

E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana a me ka pōpoki

Ke hana ʻia nei ka lāʻau lapaʻau i ke ʻano o nā papa oval i uhi ʻia me kahi membrane film. Nā pāʻālua:

• 12.5 mg - nā papa melemele
• 25 mg - kahi mālamalama ʻulaʻula.

Hoʻohana ʻia ka huahana ma ka paila pepa. Ke kīʻaha: 4 papaha, loaʻa iā 7 papa, he 28 mau ʻāpana i kahi pā.

ʻO ka waiwai ikaika o ka lāʻau alogliptin. Nā mea kōkua

• konekena stearate,
• sodium polio
• mikuleka
• Hoʻopiʻi

ʻO ka uhi ʻia o ke kiʻi paʻi o ka papa ma:

• haniailahion,
• hoʻoneʻe hao hāhi
• titanium hone
• macrogol
• aniani F1 hina

Nā hana lāʻau lapaʻau

ʻO Alogliptin he meleptidyl peptidase-4 pipili paʻa kahi koho. ʻO DPP-4 ka enzyme nui e kumu ai i ka wikiwiki o ka hoʻololi ʻana i nā hormone o ka ʻohana incretin. Ma keʻano kūikawā, he glucose-dependotine insulin -ropypypide (HIP) a me nā puhikena e like me peptide-1 (GLP-1). Hana ʻia kēia mau hormones i loko o nā ʻāpana, a ʻano like ko lākou pae ma ka ʻai i ka ʻai. Hoʻomoʻi ka hopena o ka HIP a me GLP-1 i ka hoʻopololei ʻana i ka synthesis o ka insulin i ka pancreas.

Hoʻopili i ka peptide like Glucagon e hōʻemi i ka nui o ka glucagon a hoʻolōʻihi i ka hana o nā glucose i loko o ka ate. Me nā loli o ka level o ka incretins ma lalo o ke kumu o alogliptin, hoʻonui i ka hana o ka insulin a hoʻemi ka glucoseagon me ka hoʻonui ʻana i ke kō. I ka poʻe me ka maʻi diabetes, ʻo ia mau loli e alakaʻi i ka normalization o ka hemoglobin glycosylated a me nā mea hoʻokaʻina koko ʻē aʻe ma mua a ma hope o ka ʻai.

Lapaʻau lāʻau

Hoʻopilikia ka lāʻau lapaʻau i kahi kanaka olakino a me ka mea maʻi i ka maʻi diabetes. Hoʻomoʻe ʻo Alogliptin i loko o ke kino e ka aneane 100%, me ka ʻole o ka ʻai i hoʻopau ʻia. Me ka papa pākahi, hoʻokomo koke ka mea ola i ke koko, kahi ma hope o 1 a 2 mau hola ka loaʻa ʻana o ka nui o ka lāʻau.

Hāʻalo ʻia ʻo Alogliptin e hoʻopuka nui i nā kiko. ʻO ka pilina me nā protein protein e like me 20-30%. Me ka hoʻohana mau ʻana o ka lāʻau lapaʻau, ʻo ka hōʻiliʻili o kahi mea e hana ai i ka biologically i ke kino, e like me ka ʻepekema data, ʻaʻole ʻike ʻia i nā kānaka olakino a maʻi paha. Ma loko o 21 mau hola ma hope o ka lawe ʻana i ka lāʻau lapaʻau, ʻo 70% o nā mea e hoʻopiʻi ʻia e nā keiki ma ka hana ʻole i hoʻololi ʻia, 13% e nā iwi mai.

Ua kuhikuhi ʻia ʻo Vipidia no ka maʻi maʻamau o ka lā 2. Mālama maikaʻi ka hāmeʻa i nā mea maʻi, ʻoiai me ka pani ʻole ʻole ʻana i ka meaʻai a me ka hemahema o ka hana kino pono. Hiki ke hoʻohana ʻia ka lāʻau lapaʻau e like me ka monotherapy. Hiki iā ʻoe ke inu pū me ia me nā lāʻau ʻē aʻe e kōkua ai i ka hoʻēmi ʻana o ka pauku o ke kō i ka wai koko.

Nā Hoʻohui

E like me kekahi lāʻau lapaʻau, loaʻa iā Vipidia kona mau palena. Heluhelu maikaʻi iā lākou.

ʻAʻole pono ka ʻākena me ka:

• hypersensitivity o ke kino i kekahi mea i pili i ka lāʻau lapaʻau,
• maʻi diabetes type 1
• maʻi maʻamau ketoacidosis,
• nāwaliwali o ka puʻuwai
• hoopoino nui ia,
• hapai a me lactation,
• keiki malalo o 18 makahiki.

Me ka akahele:

• lōkohu
• hano papaleha maʻi,

Nā ʻōkuhi no ka hoʻohana (dosage)

Pono ʻia ʻo Vipidia i mua a maʻa. Hoʻomaopopo ʻia e hoʻohana i nā mea hou aku ma mua o 25 mg i kēlā me kēia lā. Hoʻohua ʻia i ka manawa me ka lāʻau like, e like me:

Me ka hui pū ʻana o Vipidia me ka metformin a i ʻole thiazolidinedione, ʻaʻole i loli ke ʻano. E hoʻokaʻawale i ka hopena o ka hypoglycemia, i ka wā e kauoha ʻia ai ka lāʻau lapaʻau i ka wā like me ka insulin, pono ia e hōʻemi i ka dosage o ka hopena. Inā no kekahi kumu ke poina iā ʻoe e inu i ka lāʻau lapaʻau, pono ʻoe e hoʻoponopono hou i ka hiki. Akā i ka manawa hoʻokahi ʻaʻole hiki ke loaʻa ka hopena ʻelua.

Hōʻike ka pae o ka glucose i ke koko ma nā kiko o ke alogliptin i loko o ke kino. No laila, ʻaʻole kuhi ʻia ka lāʻau lapaʻau.

Nā hopena hopena

Aia kekahi manawa e hele mai nā hōʻailona ʻino ma muli o ka lāʻau Vipidia. Hiki i ka mea maʻi ke hoʻopiʻi i:

• lie kanikela
• ʻōpū hanu
• nasopharyngitis,
• ʻeha i loko o ka ʻōpū
• ʻeha a me ka ʻeha,
• ka hooulu ʻana o ka pancreatitis,
• ka hoʻohua ʻana o ka hana ʻole i ka pilikia.

Inā i ʻike ʻia kēlā mau hōʻailona ʻōlule, pono e hōʻike i kāu kauka. Hiki iā ia ke hoʻoholo e hoʻomau i ka mālama ʻana me ka lāʻau lapaʻau ʻaʻole paha. Hōʻikeʻike ikaika o nā hōʻailona ma luna e pono i ka haʻalele koke ʻana i ka lāʻau lapaʻau.

Ke keu

ʻAʻole hiki i kahi ākea kūʻokoʻa ke hoʻoweliweli i ka poʻe. Pono ke kōkua o ke kauka i nā hihia wale nō inā he pale ʻole ia iā Vipidia a i ʻole ke lawe ʻana i ka lāʻau lapaʻau e nā poʻe e loaʻa ana i nā maʻi i ka papa inoa o nā contraindications. ʻO ke kōkua mua no ka overdose - gastage lavage.

Nā ʻōlelo kikoʻī

ʻO ka hoʻohana kūpono ʻana o Vipidia me ka insulin a me nā lāʻau ʻē aʻe e hoʻemi ana i ke kōpaʻa koko e koi ana i ka hoʻoponopono dosage e pale i ka hoʻomohala ʻana o ka hypoglycemia. Wahi a nā haʻawina loiloi, ʻo ka launa pū ʻana o alogliptin me nā mea olakino ʻē aʻe i hōʻike ʻole i nā loli like.

Hoʻopilikia nui ʻo Alogliptin i ke kino, no laila i ka wā mālama e pono ʻoe e hōʻole i ka inu ʻona.

ʻAʻole ia ka lāʻau "Vipidia" i ka hiamoe, no laila ke kaʻa ʻole a me nā hana ʻē aʻe e koi ai ka nui o ka nānā aku.

He mea nui: ua hōʻike ʻia nā noiʻi ʻaʻole maikaʻi loa ka lāʻau lapaʻau ma ka ʻaoʻao, kahi hana ʻokoʻa i kāna mau hana. E hiki i ka wā e hiki ai ke maʻi pancreatitis. No laila, ma mua o ka hoʻohana ʻana i ka lāʻau lapaʻau, pono ia e hoʻomaʻamaʻa piha i ka hoʻohālikelike ʻana a hoʻohālikelike i nā kamaa a me nā mea ʻē.

Ma muli o ka hapa ʻole o ka ʻike e pili ana i nā kūlana ʻino i ka wā hapai a me ka lactation, ʻoi aku ka maikaʻi e inu i ka Vipidia.

Na keiki a me ko elemakule

Ke koho nei i ka lāʻau lapaʻau i nā keiki a me nā wā ʻōpio ma lalo o 18 makahiki o ka maʻi contraindicated, ma muli o ka nele o nā hōʻike maʻi i kēia makahiki.

Hiki i nā mea maʻi ma luna o 60 mau makahiki ke inu i ka "Vipidiya". ʻAʻole pono ka hoʻoponopono ʻia maʻamau e hoʻoponopono ʻia. Eia nō naʻe, pono e hāpai i ka noʻonoʻo o ka hōʻemi o ka hōʻemi o ka hana o nā pūpū a me nā ate i hilinaʻi i ka nui o ka alogliptin.

Nā kuleana a me nā kūlana e waiho ai

E hoʻomau i ka lāʻau lapaʻau ma kahi wahiʻeleʻele, anuanu ma kahi o nā keiki. ʻO ka wā i hoʻohana ʻia he ʻekolu makahiki mai ka lā o ka hoʻopuka. Hoʻohui ʻia ka lā hana o ka hoʻopili ʻana i ka pale. Ke papa ʻia i ka lāʻau kūʻai pau.

Kūlike ke kumukūʻai o Vipidia i nā lāʻau lapaʻau e like me ka nui o ke ʻano o ka lāʻau lapaʻau a me ka māhele o ka noho ʻana. I ka awelika, ʻo 845 - 1390 mau rubles.

ʻAʻole ke kūʻai ʻia ka lāʻau lapaʻau, hiki ke kūʻai ʻia wale ʻia ma ka lāʻau lapaʻau.

Hoʻohālikelike me nā kikowaena

Inā no kekahi kumu ke kūpono i ka lāʻau lapaʻau i ka mea maʻi, ke noi nei ke kauka i kahi lāʻau lapaʻau i hiki ke hoʻololi ʻia.

Ka papa inoa o nā hoʻohālikelike o ka lāʻau lapaʻau "Vipidia":

Tagu inoa	Loaʻa nā pono
Galvus Met	ʻO kahi ala e hoʻohaʻahaʻa i nā pae haʻahaʻa. Kōkua ia i ka pau ʻana o nā kauā he nui me ka ʻole hoʻokiʻī.	ʻO kahi papa nui o nā hopena pili maikaʻi. ʻO ke kumukūʻai kiʻekiʻe o ka lāʻau.	Mai 780 mau rubles.
Alogliptin	Kōkua i ka hoʻoliʻiliʻi i nā pae glucose. ʻAʻole kumu e hoʻonui i ka metabolism. ʻAʻole e hōʻiliʻili, ʻuʻuku loa ʻia mai ke kino.	ʻAʻole hiki ke hoʻohanaʻia no nā ala o nā palaka, nā aʻalima, nā pancreas. ʻAʻole maʻalahi ka lāʻau.	Mai 845 rubles.
Januvia	Hoʻopau i nā lilo kaumaha, hoʻemi i ka makemake, hoʻomaʻamaʻa i nā ʻāpana koko.	Uila. He nui nā contraindications no ka hoʻohana ʻana, no laila he mea nui a kau ke kauka i ke lāʻau lapaʻau.	Mai 1350 mau rubles

ʻO ka hapanui o nā pane mai nā maʻi maʻi maʻi e hopu ana iā Vipidia. Hoʻomaʻamaʻa maikaʻi kēia mau papaʻu i ka glucose koko, ke hoʻomanawanui maikaʻi ʻia, akā e hoʻohana wale ʻia e ke kauka. ʻAʻole makemake ka poʻe i ka ʻoiaʻiʻo o ke kumukūʻai o ka lāʻau i mea kūʻai. Eia kekahi mau ʻike maoli:

Ua maʻi wau i ka maʻi diabetes 5 mau makahiki i hala. Ua hoʻopaʻa ʻia ʻo ia me kahi endocrinologist, inu nui i nā lāʻau lapaʻau. Akā i kekahi mau pule ma hope iho, ua hoʻomaka ke kō i ke kō i ka 18 mau pūʻulu. Ua kuhikuhi mai ke kauka iaʻu i kahi Vipidia. Lawe wale wau i hoʻokahi papa pākahi i kēlā me kēia lā, maʻamau ke kō. Ua hauʻoli loa wau. Loaʻa iaʻu iho i loko o kēia lāʻau lapaʻau hoʻokahi pono wale nō.

Hoʻololi maikaʻi ʻo Vipidia i ka insulin. A i nā hoʻohālikelike me kēia, pono ke lawe ʻia i ka lā hoʻokahi i ka lā hoʻokahi. ʻAʻole pono ke mālama i kahi kīʻai. ʻO kaʻu maʻiʻai, nā papaʻu i hoʻokaʻawale i ke kiʻekiʻe o ka glucose i ke koko, no laila ua hōʻole wau i ka insulin no ka lōʻihi. Kahuikau ka ʻoiaʻiʻo i ke kumukūʻai, ʻaʻole maʻalahi ka lāʻau, ʻaʻole hiki i nā mea āpau ke loaʻa. Akā, ʻo kaʻoiaʻiʻo, aia nā pluses. Kūleʻa wau i nā mea āpau.

E loaʻa iaʻu ka maʻi diabetes 2. Hana ʻia ʻo ia, lawe i nā lāʻau lapaʻau i kēlā me kēia lā, akā ua hoʻemi ʻia ka glucose, a laila hoʻonui hou ʻia i 12 mau ʻāpana. Loaʻa nā hihia o ka hopena hypoglycemic, kahi pākeke ikaika i ka kō. Ua kuhikuhi mai ke kauka iaʻu i kahi Vipidia. Ua hauʻoli nui wau i ka lāʻau lapaʻau. Hoʻohana wau i ka papa hoʻokahi i ke kakahiaka a he maʻamau nā mea āpau. ʻOiaiʻo ka uku kumukūʻai, akā, ʻaʻole wau ʻike ʻike i nā lula i nā ʻōkuhi koko a mālie i ka lā āpau. Kūleʻa wau i nā mea āpau.

Ua hāʻawi mai ke kauka i kahi papa hana no ka kūʻai ʻana i ka lāʻau lapaʻau "Vipidia". Ua nui wau i ka maʻi diabetes i nā makahiki he nui. Makemake wau i ka lāʻau lapaʻau, hoʻohaʻahaʻa loa ia i nā hōʻailona hōʻailona glucose. ʻO wau wale nō ke inu i ka lā. ʻAʻohe contraindications inā e launa pū me nā lāʻau ʻē aʻe, e leʻaleʻa maikaʻi ʻia. ʻAʻole pili i ka psyche a ʻaʻole hoʻokū i ka hiamoe. Ke papa ʻole ʻia ana kahi kaʻa me ia. Ua hauʻoli wau i nā mea āpau, kahi hopena lapaʻau maikaʻi ʻaʻole i hopena i kahi hopena noʻu.

E hoʻokuʻu i nā palapala a me ka ʻano

ʻO ka lāʻau lapaʻau i hana i loko o kahi papa papa he 25 mg o ka waiwai ikaika - alogliptin benzoate. ʻO ke kumu nui o nā papa i hoʻohui ʻia e nā mea hoʻohui hoʻohui:

• mikuleka
• konekena stearate,
• mannitol
• sodium polio
• haiia.

ʻO ka papa o ka papa nā ʻāpana ʻāpana e pili ana i ka hypromellose, titanium dioxide, macrogol 8000, kahi kinipōpō melemele e pili ana i ka oxide iron. ʻO 25 mau papa ʻaina he ʻulaʻula.

Ka hana lāʻau lapaʻau

Aia ka lāʻau i ka papa o ka poʻe hana hypoglycemic ma muli o ke kaohi koho ʻana o ka hana o dipeptidyl peptidase-4. ʻO DPP-4 kahi kīʻaha koʻikoʻi i pili i ka hoʻohaʻahaʻa wikiwiki ʻana o nā pūhaka o ka hormonal - enteroglucagon a me ka peptide insulinotropic, e hilinaʻi nei i ka pae o glucose (HIP).

Hoʻokumu ʻia nā ʻōmaʻomaʻo mai ka papa o ka incretins i loko o ka ʻili o ka pūpū. Hoʻonui ʻia ke ʻano o nā mea kanu kemo me nā kō kai. ʻO ka peptide like-Glucagon a me ka GUI e hoʻonui i ka synthesis o ka insulin i nā mokupuni pancreatic o Langerhans. Hoʻopili ʻo Enteroglucagon i ka paleʻana i ka syntagon glucagon a pale aku i ka gluconeogenesis i nā hepatocytes, e hoʻonui ana i ka plasma o ka nui o nā kūmole. Hoʻonui ʻo Alogliptin i ka huna ʻana i ka insulin, e hilinaʻi ana ma ke kō o ke koko.

Nā hōʻailona no ka hoʻohana ʻana

Hoʻomaopopo ʻia ka lāʻau lapaʻau i nā mea maʻi no ka mālama ʻana i ka non-insulin type dependence type 2 diabetes mellitus a me ka hana maʻamau o ka mana glycemic e pili ana i ke kua ʻana o ka haʻahaʻa haʻahaʻa o ka mālama ʻana i ka lāʻau lapaʻau a me ka hana kino. No nā poʻe maʻi maʻi, hiki ke kuhikuhi ʻia ka lāʻau lapaʻau e like me ka monotherapy, a ma ke ʻano he nui o ka mālama ʻana me ka Insulin a i nā lāʻau lapaʻau hypoglycemic ʻē aʻe.

Pehea e lawe ai iā Vipidia 25?

Kuhi ʻia nā papa no ka hoʻohana waha. Hoʻomaopopo ʻia e hoʻohana i ka lāʻau me ka maʻa o 25 mg hoʻokahi i ka lā hoʻokahi, me ka loaʻa ʻana o ka meaʻai. ʻAʻole hiki ke ʻōmole nā ​​limahana o ka lāʻau lapaʻau, no ka mea ʻo ka hoʻoneʻe ʻana i ka pehu i ka hōʻemi ʻana i nā alogliptin o ka liʻiliʻi liʻiliʻi. Mai lawe i kahi pāpālua pālua.ʻO ka mea maʻi i nalowale i kahi pōpoki no kekahi kumu e pono ai e lawe iā ia i ka hiki.

Hoʻohana ʻia i ka maʻi maʻi

Manaʻo nā mea Nutrists e lawe i nā papa Vipidia ma hope o ka papa ʻaina ke piʻi ka nui o ke kō koko. Ke koho ʻana i kahi lāʻau lapaʻau ma ke ʻano he mea hana maʻalahi no ka lapaʻau me ka Metmorphine a i ʻole Thiazolidinedione, ʻaʻohe pono o ka hoʻoponopono ʻana i ka regimen dosage o nā wahi.

Me ka hoʻokele kūlike o nā derivatives sulfonylurea, ua hoʻemi ʻia kā lākou dosis e pale i ka hoʻomohala ʻana o kahi kūlana hypoglycemic. I ka pilina me ka hiki ke hiki i ka hypoglycemia, pono ia e hoʻomalu i ka pae o ke kō i ka wā o ka maʻi me Metformin, hormone pancreatic a me Thiazolidinedione pū me Vipidia.

Ma muli o ka hopena hiki i ka hypoglycemia, pono ia e hoʻomalu i ke kiʻekiʻe o ke kōpaʻa i ka wā ʻo Metformin.

Hoʻokomo ʻia kahi ʻōnaehana Pūnaewele

E pale aku i ke kua o nā mea nāwaliwali nāwaliwali, hiki i ka lesima infectious o ka papa ʻōpū o luna a me ka hoʻomohala ʻana o ka nasopharyngitis.

Ma ka ʻāpana o ka ʻili

Ma muli o ke kiko hypersensitivity, ʻike ʻia ka rashes ʻili a i ʻole ʻeha. ʻO ke ʻano, ke ʻano o ke ala o ka maʻi Stevens-Johnson, urticaria, exfoliative maʻi o ka ʻili.

I nā poʻe maʻi i hoʻomaka mua i ke ʻano o nā hopena anaphylactoid, urticaria, ua ʻike ʻia ka edema o Quincke. Ma nā pilikia koʻikoʻi, ulu ka huluhulu anaphylactic.

Hoʻohana i ka wā hāpai a me ka lactation

ʻAʻole i mālama ʻia nā haʻawina hoʻokolohua ma ka hopena o ka lāʻau lapaʻau ma ke kino o nā wahine i ka wā hāpai. I ka wā o nā hoʻokolohua ma luna o nā holoholona, ​​ʻaʻohe hopena maikaʻi o ka lāʻau lapaʻau ma luna o nā lālā o ka pilina reproduction o ka makuahine, ka embryotoxicity, a i ʻole teratogenicity o Vipidia. I ka manawa like, no nā kumu palekana, ʻaʻole i kuhikuhi ʻia ka lāʻau lapaʻau no nā wahine i ka wā hāpai (ma muli o ka hiki ke ʻeha ʻia o ka waiho ʻana o nā kau a me nā ʻōnaehana i ke kaʻina o ka ulu embryonic).

Hiki ke hoʻohālikelike ʻia ʻo Alogliptin ma o nā kelepa momona, no laila ke noi ʻia e haʻalele i ka lactation i ka wā o ka hopena o ka lāʻau lapaʻau.

Hoʻohana no ka hana renal impaired

I ka loaʻaʻana o kahi hikiʻole i ka hopena renid ma waena o ka cleance creatinine (Cl) mai 50 a 70/70 ml / min, ʻaʻohe loli hou i ka regimen dosing. Me Cl mai 29 a 49 ml / min, pono ia e hōʻemi i ka maʻamau lā i kēlā me kēia lā he 12.5 mg no hoʻokahi pākahi.

I ka loaʻaʻana o kahi hikiʻole i ka hopena renid ma waena o ka cleance creatinine (Cl) mai 50 a 70/70 ml / min, ʻaʻohe loli hou i ka regimen dosing.

Me ka hana ʻino koʻikoʻi (Cl hiki ke emi mai ka 29 ml / min), ua pāpā ʻia ka lāʻau lapaʻau.

Hoʻopili pū me nā lāʻau ʻē aʻe

ʻAʻole i loaʻa i ka lāʻau pili nā lāʻau lapaʻau me ka hoʻokūkū pū ʻana o Vipidia me nā lāʻau lapaʻau ʻē aʻe. ʻAʻole ke kālai ʻia ka lāʻau i ka hana o ka isoenzymes cytochrome P450, m izaoxygenase 2C9. ʻAʻole i launa pū me nā substrate p-glycoprotein. Ma ka Alogliptin ma ke ʻano o nā haʻawina lāʻau lapaʻau ʻaʻole i hoʻopilikia i nā loli i ke kiʻekiʻe o ka caffeine, warfarin, dextromethorphan, contraceptives waha i loko o ka plasma.

ʻAʻole hopena ka lāʻau lapaʻau i nā loli i ka pae o Dextromethorphan i loko o ke kino.

Hoʻolaha ka waipuna

I ka wā o ka mālama ʻana me ka lāʻau lapaʻau, pāpā ʻia i ka inu ʻawa. ʻO ka Ethanol i loko o nā mea inu wai hiki ke hoʻonāukiuki i ka momona o ka ate ma muli o nā hopena o nā pakanā hepatocytes. Ke lawe nei i Vipidia, e hoʻonui ʻia ka hopena o ka mea ʻino e kūʻē i ka ʻōnaehana hepatobiliary. Hoʻopilikia ka waiona Ethyl i ka pale ʻana o ke kaila o ka pīpī, ua hoʻokomo ʻia ke kahe koko a he hopena diuretic. Ma muli o ka hopena o ka hopena o ka waiʻona ma ke kino, ua hoʻemi ʻia ka hopena therapeutic i ka lāʻau.

ʻO nā mea hoʻohālike o ka lāʻau lapaʻau e like me nā huahana lapaʻau e like me nā mea hoʻonāukiuki a me nā mea hoʻonāukiuki o ka mea ikaika e kū nei:

Koho ʻia ka lāʻau synonym e ka mea hele i ke kauka e hilinaʻi nei ma nā kuhikuhi o ke kaila koko koko a me ke ʻano maʻamau o ka mea maʻi. Hoʻololi ʻia ka loli i ka hana ʻole o ka hopena therapeutic a i ʻole e kū i kahi papa o nā ʻano maikaʻi ʻole.

Nā hōʻailona a me nā contraindications no ke hoʻohana

ʻO Vipidia ka lāʻau lapaʻau waha wahaʻikaʻi. Hoʻohana ʻia kēia mea hana i ka mālama ʻana i ka maʻi diabetes 2 type. Hāʻawi kēia lāʻau maʻi diabetes i ka hoʻomaikaʻi ʻana i ka kaohi o ka glycemia i ke koko koko o kahi mea maʻi. Ke hoʻohana ʻia kahi lāʻau lapaʻau i ka wā e hoʻohana ai ka lāʻau lapaʻau i ka lāʻau a me ka hana hoʻoikaika kino e hāʻawi i ka hopena i makemake ʻia.

Hiki i ka lāʻau lapaʻau ke hoʻohana wale i ka mea wale nō i ka wā monotherapy. Eia kekahi, hiki ke hoʻohana pū iā Vipidia i ka hui pū me nā lāʻau hypoglycemic ʻē aʻe i ka mālama ʻana i ka diabetes mellitus type 2 e ke ʻano o ka ʻoihana paʻakikī.

Hiki ke hoʻohana ʻia ka lāʻau lapaʻau i ka mālama ʻana i ka maʻi diabetes i ka hui pū ʻana me ka insulin.

E like me kekahi lāʻau lapaʻau, loaʻa i ka Vipidia nā contraindications e palena i ka hoʻohana ʻana i ka lāʻau. ʻO nā huaʻōlelo nui nā maʻi like:

• ka heleʻana o ka maʻi type type 2 i ka mea maʻi, hypersensitivity i nā alogliptin a me nā mea kōkua o ka lāʻau,
• ua maʻi ka mea maʻi ma kahi ʻano i kau ʻia e ka insulin,
• ka ʻike ʻana i nā hōʻailona o ka ketoacidosis e ulu ana i ke kino o ka mea maʻi ma ke kua o ka maʻi maʻi,
• ka ʻike ʻana i ka hana ʻo ka puʻuwai kaumaha,
• nā pilikia i ka puʻuwai, ka mea i hui pū ʻia e ka loaʻa ʻana o nā hana kūpono,
• ka hoʻomohala ʻana o nā ala ʻōpuhi koʻikoʻi, ka mea i hui pū ʻia me ka loaʻa ʻana o ka hana hoʻopulapula,
• ka manawa hānau o ke keiki,
• lactation wā
• i ka 18 makahiki o ko ka mea maʻi.

Pono e mālama ʻia a ʻo ka mea maʻi me ka pancreatitis a me ka pae o ka hōʻemi ʻana i nā hana ma ka hana o nā pūpū a me nā ate.

Eia kekahi, pono e hoʻomaʻemaʻe e mālama i ka wā e hoʻohana ai i ka lāʻau lapaʻau ma ke ʻano he ʻano ma ka mālama ʻana o ka maʻi maʻamau o ka maʻi maʻamau.

Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau

Lawe ʻia ka lāʻau lapaʻau. ʻO ka pinepine, ʻo ka lāʻau therapeutic i ʻōlelo ʻia no ka hoʻohana ʻana he 25 mg.

ʻO kahi maʻa mau ka pololei o ka hoʻohana ʻana i kahi lāʻau lapaʻau i kuhikuhi ʻia e ke kauka hele ʻana e noʻonoʻo ana i nā hopena i loaʻa i ka wā o ka hoʻokolokolo ʻana i ke kino o ka mea maʻi a me kāna ʻano pilikino.

Lawe ʻia ka lāʻau i hoʻokahi manawa i ka lā, e lawe ʻia ka lāʻau me ke koena o ka papa ʻaina meaʻai. Ke lawe nei i ka lāʻau lapaʻau me ka inu ʻana i ka wai nui.

Loaʻa ka hoʻohana ʻana i kahi lāʻau lapaʻau i kēia mau hihia:

1. ʻO kahi mea lapaʻau no ka monotherapy o type 2 diabetes mellitus.
2. I ka hoʻokō ʻana i kahi mālama paʻakikī o ka maʻi, ma ke ʻano he ʻano hoʻohālike o ia ʻano. E hele pū me ka vipidia, metformin, kinikini sulfonylurea a i ʻole insulin e lawe ʻia.

I ka hihia o Vipidia me ka hui me Metformin, ʻaʻole koi ʻia ka hoʻoponopono ʻana i ka maʻi o ka lāʻau. Pono ke hoʻoponopono ʻana i ka dosis i ka wā e hoʻohana ai i ka lāʻau lapaʻau e hui pū ai me nā lāʻau lapaʻau e pili ana i ka sulfonylurea a i ʻole insulin.

Hoʻoponopono ʻia ka lāʻau lapaʻi e pale i ka hoʻomaka ʻana o nā hōʻailona o ke kūlana hypoglycemic i ka mea maʻi me ka maʻi mellitus.

Pono e hoʻonui ka makaʻala ke hoʻohana ʻana iā Vipidia i hui pū me Metformin Teva a me thiazolidinedione i ka mālama ʻana i ka maʻi maʻi maʻi.

Ke hele nei nā hōʻailona koʻikoʻi o ka hypoglycemia, pono e hoʻoneʻe ʻia ka nui o ka Metformin a me thiazolidinedione.

Ke lawe a Vipidia, hiki mai nā hopena like ʻole:

• mai ka ʻōnaehana o ka pilikia, ka hopena o nā hōʻeha o ka maʻi maʻamau,
• mai ka ʻōpū o ka gastrointestinal, ka hiʻohiʻona o ka ʻeha ma ka ʻōpū, e hoʻolei i nā mea i loko o ka ʻōpū i loko o ka esophagus, ka hoʻomohala ʻana i nā hōʻailona o ke aʻoki o ka pancreatitis,
• mai ka ʻōnaehana hepatobiliary, ka hopena i nā mea hoʻonāukiuki i ka loko o ka ate,
• kūloko paha ka hopena i loko o ke ʻano o ka haki, rashes, ka edema Quincke,
• hiki ke kūleʻa a me ke kuahiwi o ka ihu mucosa a me ka pharynx.

Eia nā mea ʻē aʻe, hiki i nā hopena ʻaoʻao mai ke ʻōnaehana o ka maʻi ke hanana nei, e hōʻike ana me ka anaphylaxis.

Nā Hōʻikeʻike iā Vipidia 25

Ma nā papa kūkākūkā pūnaewele loaʻa nā ʻōlelo maikaʻi mai nā lāʻau lapaʻau a me nā ʻōlelo kōkua no ka hoʻohana ʻana o ka lāʻau lapaʻau.

Anastasia Sivorova, endocrinologist, Astrakhan.

He pono hana ma ka hakakā me nā maʻi maʻi type 2. Hoʻomaʻamaʻa maikaʻi ʻia nā maʻi. Ma nā hoʻomaʻamaʻa kulekele, ʻaʻole i hui i ka hypoglycemia. Pono e lawe ʻia nā papa i 1 manawa i kēlā me kēia lā me ka ʻike ʻole ʻana ma ka helu ʻana me ka helu ʻana. ʻO kahi kahu hypoglycemic mai kahi hanauna hou, no laila, ʻaʻole i hāʻawi i ka hoʻonui ʻana i ke kaupaona kino. Mālama ʻia ka hana hana o nā kōpena beta pancreatic.

ʻO Alexey Barredo, ka mea hoʻokau manuahi, Arkhangelsk.

ʻO wau makemake me ka hoʻohana mau ʻana o ka lāʻau lapaʻau, ʻaʻole mau ka hōʻike hoʻomohala. Loaʻa ka hopena therapeutic i ka hopena hypoglycemic maʻalahi, akā ʻaʻole hiki ke ʻike koke ʻia. He kūpono ka lawe - 1 mau lā i ka lā. Loaʻa maikaʻi kālā no ke kālā. ʻAʻole ia e hoʻokau i ka hopena alerine i nā maʻi.

ʻO kahi analogue o ka lāʻau lapaʻau ʻo Januvia.

Gabriel Krasilnikov, 34 makahiki, Ryazan.

Lawe au iā Vipidia ma ke ʻano o 25 mg no 2 mau makahiki me ka 500 mg o Metformin i ke kakahiaka ma hope o ka ʻai ʻana. I ka mua, ua hoʻohana ʻo ia i ka Insulin e like me ka papa hana 10 + 10 + 8 mau ʻāpana. ʻAʻole i kōkua maikaʻi i ka hōʻemi i ke kō. He lōʻihi ka hana a nā papa. Ma hope o 3 mau mahina, e hoʻomaka ka honu gula, akā ma hope o ʻeono mahina, ua hāʻule ka glucose mai ka 12 i ka 4.5-5.5. Hoʻomau ka noho mau i loko o 5.5. ʻO wau makemake i hoʻemi ʻia ke kaumaha: mai 114 a 98 kg me ka piʻi o 180 cm. Akā, pono ʻoe e hahai i nā ʻōlelo a pau mai nā ʻōlelo aʻoaʻo.

Nā kumumanaʻo i ka mea haku mele a me nā hōʻike no ka hoʻohana

Ke poʻo inoa	He kumukūʻai ma Rusia	Kumukūʻai ma Ukraine
Nesina alogliptin	--	--

ʻO ka papa inoa ma luna o nā mea hoʻohālikelike lapaʻau, e hōʻike ana Hoʻolaha nā Vipidia, kūpono loa ia no ka mea ua like lākou me ka like o nā mea hana a me ke kūleʻa e like me ke kuhikuhi ʻana no ka hoʻohana

Nā kumumanaʻo e ka hōʻike a me ke ʻano o ka hoʻohana

Ke poʻo inoa	He kumukūʻai ma Rusia	Kumukūʻai ma Ukraine
ʻO Jasonvia sitagliptin	1369 ʻōpala	277 UAH
Galvus vildagliptin	245 ʻōpala	895 UAH
Onglisa saxagliptin	1472 ʻōpala	48 UAH
Trazhenta linagliptin	89 ʻōpala	1434 UAH

Ka ʻokoʻa like, hiki ke pili pū i ka hōʻike a me ke ʻano o ka noi

Ke poʻo inoa	He kumukūʻai ma Rusia	Kumukūʻai ma Ukraine
Avantomed rosiglitazone, metformin hydrochloride	--	--
Bagometua Metformin	--	30 UAH
He metformin Glucofage	12 ʻōpala	15 UAH
Huʻi ʻia ka metformin xr	--	50 UAH
ʻO Reduxin Met Metinin, ʻo Sibutramine	20 ʻōpala	--
Dianormet	--	19 UAH
Metformin Diaformin	--	5 UAH
ʻO ke metformin metformin	13 ʻōpala	12 UAH
Metformin metozin metformin	--	13 UAH
Siofor	208 ʻōpala	27 UAH
ʻO ka metformin hydrochloride	--	--
ʻO Emnorm EP Metformin	--	--
Megifort Metformin	--	15 UAH
Metamine Metformin	--	20 UAH
Metamine SR Metformin	--	20 UAH
Metfogamma metformin	256 ʻōpala	17 UAH
ʻO Tefor metformin	--	--
Glycometer	--	--
Glycomet SR	--	--
Kālaiʻa	37 ʻōpala	--
Metformin Canon metformin, ovidone K 90, mauʻa palaoa, crospovidone, magnesium stearate, talc	26 ʻōpala	--
Insuffor metformin hydrochloride	--	25 UAH
Metformin-teva metformin	43 ʻōpala	22 UAH
Diaformin SR metformin	--	18 UAH
Mepharmil Metformin	--	13 UAH
Metformin Metformin	--	--
ʻO Glibenclamide Glibenclamide	30 ʻōpala	7 UAH
Maninyl Glibenclamide	54 ʻōpala	37 UAH
ʻO ka Glibenclamide-Health Glibenclamide	--	12 UAH
Glyurenorm glycidone	94 ʻōpala	43 UAH
ʻO Bisogamma Glyclazide	91 ʻōpala	182 UAH
ʻO Glidiab Glyclazide	100 rub	170 UAH
Diabeton MR	--	92 UAH
Diagnizide mr Gliclazide	--	15 UAH
ʻO Glidia MV Gliclazide	--	--
ʻO Glykinorm Gliclazide	--	--
Hoʻolaha ʻia Gliclazide	231 rub	44 UAH
Glyclazide 30 MV-Indar Glyclazide	--	--
Hoʻolaha-Hoʻolima Glyclazide-Health	--	36 UAH
ʻO Glioral Glyclazide	--	--
Hoʻolaha Glaclazide Diagnizide	--	14 UAH
Diazide MV Gliclazide	--	46 UAH
Osliklid Gliclazide	--	68 UAH
Gliclazide Diadeon	--	--
ʻO Glyclazide MV Gliclazide	4 ʻōpala	--
Amaril	27 ʻōpala	4 UAH
Glimepiride ʻO Glemaz	--	--
Hoʻolaha ʻia ka inoa momona	--	77 UAH
ʻO Glimepiride Glyride	--	149 UAH
Diapiride Glimepiride	--	23 UAH
Alarahi	--	12 UAH
Hoʻolālā ʻia ʻo Glimax	--	35 UAH
Gimepiride-Lugal glimepiride	--	69 UAH
Clay glimepiride	--	66 UAH
Glabepiride diabrex	--	142 UAH
Nā glimepiride ʻo Meglimide	--	--
Melpamide Glimepiride	--	84 UAH
ʻO ka glimepiride Perinel	--	--
Hoʻohui	--	--
Kahiʻu	--	--
Gimepiride glimepiride	27 ʻōpala	42 UAH
ʻO Glimepiride-teva glimepiride	--	57 UAH
Gimepiride Canon glimepiride	50 ʻōpala	--
ʻO Glimepiride Pharmstandard glimepiride	--	--
Dimaril glimepiride	--	21 UAH
ʻO Glamepiride diamerid	2 hoʻoheʻe	--
Amaryl M Limepiride Maikaʻi ʻia, Metformin Hydrochloride	856 ʻōpala	40 UAH
ʻO ka glibenclamide glibomet, metformin	257 ʻōpala	101 UAH
ʻO Glucovans glibenclamide, metformin	34 ʻōpala	8 UAH
Dianorm-m Glyclazide, Metformin	--	115 UAH
Dibizid-m glipizide, metformin	--	30 UAH
Douglimax glimepiride, metformin	--	44 UAH
Duotrol glibenclamide, metformin	--	--
Hoʻolauleʻa	45 kahi	--
Glibofor metformin hydrochloride, glibenclamide	--	16 UAH
Avandamet	--	--
Avandaglim	--	--
ʻO metumin metumin, sitagliptin	9 ʻōpala	1 UAH
Velmetia metformin, sitagliptin	6026 rub	--
Galvus Met vildagliptin, metformin	259 ʻōpala	1195 UAH
ʻO glimepiride Tripride, metformin, pioglitazone	--	83 UAH
Huihui XR metformin, saxagliptin	--	424 UAH
Metformin Comboglyz Prolong, saxagliptin	130 ʻōpala	--
Gentadueto linagliptin, metformin	--	--
ʻO ka metformin Vipdomet, alogliptin	55 ʻ .pū	1750 UAH
Sinjardi empagliflozin, metformin hydrochloride	240 ʻōpala	--
ʻO Voglibose Oxide	--	21 UAH
He pioglitazone Glutazone	--	66 UAH
ʻO Dropia Sanovel pioglitazone	--	--
Lixumia lixisenatide	--	2498 UAH
Guanem guar gum	9950 ʻōpala	24 UAH
Hoʻopau ka Insvada	--	--
Novonorm Repaglinide	30 ʻōpala	90 UAH
Hoʻokomo ʻo Repodiab Repaglinide	--	--
Baeta Exenatide	150 ʻōpala	4600 UAH
Baeta Long Exenatide	10248 ʻōpala	--
Viktoza liraglutide	8823 kahaki	2900 UAH
Saxenda liraglutide	1374 ʻōpala	13773 UAH
Forksiga Dapagliflozin	--	18 UAH
Forsiga Dapagliflozin	12 ʻōpala	3200 UAH
Invocana canagliflozin	13 ʻōpala	3200 UAH
Jardins Empagliflozin	222 ʻōpala	566 UAH
Trulicity Dulaglutide	115 ʻōpala	--

Pehea e ʻike ai i kahi analogue ʻano maʻalahi o kahi lāʻau lapaʻau nui?

No ka ʻike ʻana i kahi analogue kūʻai like ʻole i ka lāʻau lapaʻau, kahi generic a i ʻole synonymation, ʻo ka mea mua mua mākou i manaʻo no ka hoʻolohe ʻana i ka hoʻopili ʻana, ʻo ia nā ʻano like ʻole o nā mea kaha a me nā hōʻailona no ka hoʻohana. Hōʻike ka mea like ʻole o ka lāʻau lapaʻau me ka lapaʻau a like pū me ka lāʻau lapaʻau, kūloko a me ka mea pono i ʻole nā ​​lāʻau lapaʻau. Eia naʻe, mai poina e pili ana i nā māhele like ʻole o nā lāʻau like like, e hiki ai ke hoʻopilikia i ka palekana a me ka hana. Mai poina e pili ana i nā kauoha a nā kauka, hiki i ka lāʻau lapaʻau ponoʻī ke hōʻeha i kou olakino, no laila e ʻōlelo mau i kāu kauka ma mua o ka hoʻohana ʻana i kekahi lāʻau lapaʻau.

ʻĀnoʻi Vipidia

NA ININA
i ka hoʻohana 'ana i nā kālā
Vipidia

Pākuʻi helu
12.5 mg a me 25 mau papa ʻoniʻoni a 25 mg

Hōʻike
Aia ma ka papa papa
mea waiwai: alogliptin benzoate 17 mg (like me ka 12,5 mg o ka alogliptin) a me 34 mg (like me 25 mg o ka alogliptin)
nā mea hoʻowalewale:
ʻAkuhi: mannitol, microcrystalline cellulose, hydroxypropyl cellulose, sodium croscarmellose, magnesium stearate,
ʻO ka hui pū ʻana o ka membrane film: hypromellose 2910, titanium dioxide (E 171), ka hao o ka oxide (E 172), ka ulaula pōpoki hao (E 172), ka polyethylene glycol 8000, ke aniani hina F1

ʻO keʻano
ʻO nā papa bvalvex oval, i kāwili ʻia me ka uhi ʻulaʻula melemele, i kapa ʻia ʻo "TAK" a me "ALG-12.5" ma kahi ʻaoʻao o ka pākaukau (no kahi pāʻālua o 12,5 mg).
ʻO nā papa o Bvalvex i kāwili ʻia me kahi membran kiʻi i ke kala ʻulaʻula māmā, me nā huaʻōlelo "TAK" a me "ALG-25" ma kahi ʻaoʻao o ka pākaukau (no ke ʻano he 25 mg).

ʻĀpana Pharmacotherapeutic
Me ke kumu o ka mālama ʻana i ka maʻi maʻi. ʻO nā haʻahaʻa hoʻoliʻi haʻahaʻa no ka hoʻokō waha. Nā mea hōʻike o dipeptidyl peptidase-4 (DPP-4). Alogliptin

Pāʻālua ATX A10BH04

ʻO nā waiwai Pharmacological
Lapaʻau lāʻau
Ua aʻo ʻia nā pharmacokinetics o alogliptin i nā haʻawina e pili ana i nā limahana olakino olakino a me nā mea maʻi me ka maʻi diabetes type 2.I nā mea hana olakino olakino, ma hope o ka lawelawe waha hoʻokahi a hiki i 800 mg o ka alogliptin, ʻike pinepine ʻia ka lāʻau i ka hoʻopau ʻana i ka plasma kiʻekiʻe loa i hoʻokahi a ʻelua mau hola mai ka manawa o ka hoʻokele (average Tmax). Ma hope o ka lawe ʻana i ka nui o ka lāʻau therapeutic i hōʻike ʻia i ka lāʻau (25 mg), kahi hapalua o ke ola (T1 / 2) i hōʻea i nā hola he 21.
Ma hope o ka hoʻokele hou ʻana a hiki i 400 mg no 14 mau lā i ka poʻe maʻi me ka maʻi type 2, ua ʻike ʻia ka hōʻemi ʻana o nā alogliptin me ka hoʻonui ʻana o ka wahi ma lalo o ka pāpaʻi pharmacokinetic (AUC) a me ka uʻi nui o ka plasma (Cmax) ma kahi o 34% a me 9%. Me nā pālua ʻelua a me ka nui o ka alogliptin, hoʻonui ʻia ka AUC a me Cmax i ka hoʻonui ʻana i ka hoʻonui ʻana i ka maʻi mai 25 mg a 400 mg. ʻO ka coefficient o ka ʻano o ka AUC o alogliptin ma waena o nā mea maʻi e liʻiliʻi (17%).
Kapehu
ʻO ka bioavailability piha o alogliptin e pili ana i ka 100%. Mai ka wā e lawe ai i ka alogliptin me ka meaʻai me ka momona momona kiʻekiʻe, ʻaʻohe hopena i loaʻa iā AUC a me Cmax, hiki ke inu ʻia ka lāʻau lapaʻau ma kahi o ka ʻai.
Kahele
Ma hope o kahi hoʻomalu alogliptin kū hoʻokahi i kahi maʻi o 12.5 mg i nā limahana olakino, ʻo ka hoʻonui ʻana i ke kīpī ma ka pae terminal he 417 L, e hōʻike ana i ka alogliptin i hoʻolako maikaʻi ia i nā kiko.
ʻO ka kamaʻilio me nā protein plasma he 20%.
Hāpai
ʻAʻole i lawe ʻia ʻo Alogliptin i ka metabolism nui, ma muli o kahi o 60% a me 71% o ka waiʻai i hoʻopau ʻia ua hoʻololi ʻia i loko o ka urine. Ma hope o ka hoʻoponopono waha ʻana o ka alogliptin hōʻailona 14C, ua hoʻoholo ʻia nā metabolites liʻiliʻi ʻelua: N-demethylated alogliptin M-I (˂1% o nā kumu hoʻomaka) a me N-acetylated alogliptin M-II (˂6% o ka mea hoʻomaka). ʻO M-I kahi metabolite ikaika a me ka mea hoʻomau i koho ʻia ʻo DPP-4, e like me ka hana me ka alogliptin, ʻaʻole hōʻike M-II i ka hana pale me ka DPP-4 a i ʻole nā ​​mea hou e like me DPP-like. Ua hōʻike i nā haʻawina vitro ua kōkua ka CYP2D6 a me CYP3A4 i ka palena liʻiliʻi o ka metabolism o ka alogliptin. Ke loaʻa nei ʻo Alogliptin ma ke ʻano o ka (R) enantiomer (> 99%) a ma lalo o nā kūlana vivo i ka liʻiliʻi o ka hoʻololi chiral i ka (S) enantiomer. (S) ʻaʻole ʻike ʻia -enantiomer i ka wā e lawe ai i ka alogliptin i loko o nā wai therapeutic (25 mg).
Leʻaleʻa
Ma hope o ka hoʻomalu ʻana o ka alogliptin 14C-hōʻailona ʻia, ʻo 76% o ka huina o ka radioactivity ka mea i hoʻopiʻi ʻia e nā ʻōpū a me 13% ma o nā ʻāpana, a hiki aku i ka 89% o ka nui o ka radioaktif oponopono. ʻO ka wehe ʻana o Renal i ka alogliptin (9.6 L / h) e hōʻike ana i ka ʻōlelo huna renal tubial. ʻO ka huakaʻi o ka ʻōnaehana he 14.0 l / h.
Pharmacokinetics i loko o nā hui hoʻomanawanui kūikawā.
Hola paʻa kino hana
AUC o alogliptin i nā mea maʻi me ka hana ʻole o ka ʻōpū o ka hanu o ke kaumaha (60≤ creatinine clearance (CrCl) ʻAi ʻia ka ʻike a pau no ka ʻike ʻike a ʻaʻole kumu he kumu hoʻopukuhua a koho paha i kahi lāʻau lapaʻau.

ʻO ke kumukūʻai o Vipidia a me kāna hoʻopili

ʻO ka hoʻohana pinepine ʻana o nā papa Vipidia no ka maʻi maʻi maʻi maikaʻi.

Inā mākou e hoʻokolokolo i ka lāʻau lapaʻau ma o nā loiloi a ke poʻe e hoʻohana nei iā Vipidia e waiho e pili ana i ia mea, hiki iā mākou ke manaʻo e kī maikaʻi loa ka lāʻau lapaʻau e hiki ai ke kāohi i ka pae o ka glycemia i loko o ke kino o kekahi e loaʻa ana i ka maʻi maʻamau ʻo type.

ʻO nā lāʻau lapaʻau ka mea kanu ikaika, ʻo ia ka alogliptin a hiki i kēia lā, ma kahi o Vipidia ʻaʻole i hoʻopaʻa inoa.

Hoʻokō ʻia nā lāʻau lapaʻau, nā hana ikaika o ia mau pūhui e pili ana i ka incretinomimetics hui.

ʻO nā lāʻau lapaʻau maʻamau loa e pili ana i ka hoʻohālikelike o Vipidia:

1. ʻO Jasonvia kahi lāʻau hypoglycemic i hoʻokumu ʻia ma ka kumu o sitagliptin. ʻO ke hoʻokuʻu o ka lāʻau lapaʻau i ke ʻano o nā papa i loaʻa ka 25, 50 a me 100 mg o ka hana ikaika. Hoʻohālikelike nā hōʻike no ka hoʻohana ʻana iā Januvia i nā mea a Vipidia i loaʻa. Hiki i kēia lāʻau lapaʻau me ka monotherapy a i ʻole me ka mālama paʻakikī.
2. ʻO Yanumet kahi hoʻomākaukau paʻakikī, kahi o ka sitagliptin a me ka metformin e like me nā mea ikaika. ʻO ka makeʻana o ka hana hana mua he 50 mg, a me ka metformin i ke ʻano o ka lāʻau i loko o nā ʻano he nui. Loaʻa ka lāʻau lapaʻau i ʻekolu mau ʻano - 50, 850 a me 1000 mg.
3. ʻO Galvus ma kahi ʻano ikaika he vildagliptin, he mea hoʻohālikelike ia o alogliptin. ʻO ka makeʻana o ka hana ikaika i ka hoʻomākaukau no 50 mg. ʻO ka helu o ka metformin i ke ʻano o ka lāʻau lapaʻau he 500, 850, a me 1000 mg.
4. ʻO Onglisa i kona ʻano he pūhui neʻe me ka saxagliptin. Ua pili kēia pūlea i nā pūhui like ʻole o ka pale o ka molelule depleting. Loaʻa ka lāʻau lapaʻau i loko o kahi waihona o 2.5 a me 5 mg.
5. ʻO ka Comboglyz Prolong ka hui pū ʻana o kahi saxagliptin me ka metformin. Loaʻa kēia lāʻau lapaʻau i ka palapala hana. ʻO ka hoʻokuʻu mai o nā mea hana i hana i kahi hoʻopalike.
6. ʻO Trazhenta kahi lāʻau lapaʻau hypoglycemic i kumu o ka linagliptin. ʻO ka hiʻohiʻona o ka lāʻau lapaʻau ka 5 mg o ka hana ikaika.

ʻO ke kumukūʻai o kahi lāʻau lapaʻau e hilinaʻi nei i nā wahi kahi i kūʻai aku ai ka lāʻau lapaʻau ma Russia. ʻO ke kumukūʻai kūpono o kēia lāʻau lapaʻau he 843 mau rubles.

Hiki ke hoʻohana ʻia nā lāʻau ʻē aʻe ma ka mālama ʻana i ka maʻi maʻi i ka wikiō ma kēia ʻatikala.