ʻO ka hoʻomauʻana o ka insulin (human genetic engineering): noi

Hoʻohana ʻia e mālama ia i nā ʻano maʻi like ʻole. Hāʻawi i nā wahine hāpai, inā ʻaʻole i hāʻawi iki nā hopenaʻai i ka hopena, e like me ka wā hānau. He kūlohelohe paha ka insulin kanaka hana i ka hana, hōʻeha, maʻi ʻeha, i hele pū ʻia e ke kuni.

Hiki wale i ke kauka ke kahakaha i ka hewa a me ke ʻano o ka lawelawe ʻana o ka lāʻau lapaʻau, ʻoiai i kēlā me kēia hihia ke hilinaʻi nei ia i nā ʻano pilikino o ke ʻano o ka maʻi.

ʻO ka manawa pinepine, ua hana ʻia kahi inake subcutaneously, 15-30 mau minuke ma mua o ka pāʻina. Hiki iā ʻoe ke komo pū ma loko mai a me ka intramuscularly. ʻO ka helu maʻamau o nā injections i 3 mau lā i ka lā. Ma mua o ka hoʻonāukiuki ʻana, pono ʻoe e ʻike pono ka pahu kīpē me ka lāʻau lapaʻau i ka waʻa o ke keʻena, a me ka wai o loko o ia mea he kīnā ʻole. ʻO ka hoʻohana ʻana i ka lāʻau lapaʻau me nā ʻano opacities a pau ʻole.

Hoʻopau ʻia ka hoʻohālikelike o ka insulin i ka hihia o nā kolohe o ke kino o ke kanaka, inā e loaʻa ana:

nā maʻi ʻohi
pilikia pilikia tiro
ʻO ka maʻi Addison
hipapoliona,
maʻi ma ke aniani i nā kānaka he 65 a keu paha.

Hiki i nā pae Glucose ke hāʻule i lalo loa nā kumu:

ka loli o ka pūnaewele injection,
ʻOke lāʻau
ka hoʻoikaika kino
nā pilikia me ka gastrointestinal tract
hopena i ka hoʻohana ʻana i nā lāʻau lapaʻau ʻē aʻe,
i ka wā e hoʻoneʻe ana i ka maʻi maʻi i ka insulin kanaka.

Hoʻi i ka papa o nā kikoʻī

Makemake au (mai ka ʻōlelo Latin - insulin in solution) ʻokoʻa kahi inoa kālepa ʻokoʻa. Aia ia i ka lōʻihi o ke kinona a me ke kaʻina hana. Loaʻa ka loaʻa ʻana o ka insulin i ka hana kanaka me ka ʻenehana. E hoʻoholo kēia mea i kona lōʻihi. Aia kekahi mea waiwai - he lua-hana inikua, me kahi manawa like o ka hōʻike. Hoʻokaʻawale ʻia nā pūʻulu o nā lāʻau lapaʻau:

Ka lōʻihi o ka hūnā i nā hiʻohiʻona Hōʻikeʻike i nā lāʻau lapaʻau Kīwī e hana ʻia nā hōʻailona mua loa ma hope o 30 mau minuke ma hope o ka hoʻokele ʻana o Humulin, Rinsulin, Gansulin ʻoi ka hoʻomaka ʻana ma loko o nā hola 2-3, Insuran Bioinsulin Medium mau hana E hoʻomaka ai nā hōʻailona ma loko o 1 mau hola, hōʻike ikaika - ma hope o 6-7 mau hola "Boisulin" "Protafan" Ma hope o 12 mau hola, "Inumanu" hoʻopau loa ʻia mai ke kino. hiki ke hoʻololi i ka lōʻihi o ka hana ma ke kino o "Gansulin" ʻO "Gensulin" Ua pili pili ʻia me ka hoʻohana ʻana i ka meaʻai "Mikstard" Pākuʻi 2 mau manawa i ka lā, 30 mau minuke ma mua o ka papa i ka papa o nā manaʻo.

ʻO ke kaila koko hoʻoneʻe ʻia, ʻo ka hypersensitivity wale nō nā contraindications e hoʻohana ana i ka insulin. ʻO nā hopena ʻaoʻao ka maʻi maʻi, ma ke ʻano urticaria, hypoglycemia. Hiki iā ʻoe ke nānā:

leo koma
nā huina o nā io a me nā ʻōnaehana cardiovascular,
pilikia me ka haʻiʻike a me ka hihiʻo,
hilahila
pālahalaha maʻi
huehue ma ka wahi i ʻōlelo ʻia.

Hoʻi i ka papa o nā kikoʻī

Kūleʻa ka hoʻomehana kanaka (kanaka genetic engineering) me nā lāʻau lapaʻau ʻē aʻe. Sulfanilamide a me nā lāʻau lapaʻau, a me ka tetracyclines, theophylline, quinidine, quinine, ethanol, e hoʻemi i ka kaila o ka glucose i loko o ke koko. Ma nā mea ʻē aʻe, ua hoʻonui ʻia kāna ʻike: diuretics, hormones thyroid, antidepressants, marijuana, nicotine, epinephrine, oral contraceptives.

ʻO ka moʻolelo o kekahi o kā mākou mea heluhelu, ʻo Inga Eremina:

Ke kaumaha nei koʻu koʻikoʻi, kau paona ʻia e like me 3 sumo wrestlers i hui pū ʻia, ʻo ia hoʻi ʻo 92kg.

Pehea e kāohi ai i ka momona nui? Pehea e kū ai i nā loli hormonal a me ka momona. Akā ʻaʻohe mea kūpono ʻole a ʻōpio paha i kahi kanaka e like me kāna kiʻi.

Akā he aha ka mea e hāʻawi ai i ka nalo? Ana i ka lawena? ʻIke au - ma kahi o 5 tausani mau kālā. Nā ʻōnaehana paʻakikī - massage LPG, cavitation, RF hāpai, myostimulation? Ke hoʻolako liʻiliʻi ia - nā kumu papa mai 80 tausani mau rubles me kahi mea aʻoaʻo aʻoaʻo aʻoaʻo. Hiki iā ʻoe ke ʻimi ʻolo e holo ma luna o kahi ʻano kapuahi, a hiki i kahi pupule.

A hea lā hea ka manawa a kēia manawa? ʻAe a kūʻai lilo loa. I kēia manawa. No laila, iaʻu iho, ua koho wau i kahi ala ʻē aʻe.

I kahi kūlana o ka lāʻau lapaʻau nui loa, ke manaʻo nei kekahi kanaka i ka pōloli, ka ʻeha, ka wīwī, kahe ʻana o ke koko. ʻO ka mea maʻi e like me ke kūlana hiamoe. I nā hoʻomaka mua o ka maʻi, hele ke kanaka i kēia mau hōʻailona i kāna iho. Nui ka ʻai i nā meaʻai i ke kō, inu i nā wai momona carbonated. Inā ʻoe i ka lāʻau "Glucagon" ma ka lima, hāʻawi i kahi maʻi.

ʻO ka hoʻowili ʻana o ka insulin soluble kanaka genetically engineered me nā mea ʻē aʻe

Me ka overdose o ka lāʻau lapaʻau, ulu ka hypoglycemia (ke anuanu maloʻo, nāwaliwali, ka palapa o ka ʻili, nā haʻalulu, nā palpitations, nā hopohopo, ka paresthesia i nā wāwae, nā lima, ka huaʻōlelo, nā lewa, ka pōloli, ka hōʻeha o ke poʻo), nā hōʻeha, ka hypoglycemic coma. Hoʻomaʻamaʻa: hiki i ka mea maʻi ke hoʻopau i ka hypoglycemia palupalu ma kāna iho ma kaʻai ʻana i ka meaʻai me nā mea i kālai a i ke kō paha. Hoʻokomo ʻia ka Glucagon i ka subcutaneously, intravenously, intramuscularly, a i ʻole ka hopena hypertonic dextrose e mālama ma ka intravenously, me ka hypoglycemic coma, 20-40 ml (a hiki i 100 ml) o kahi hopena o 40% dextrose e hoʻopaʻa ʻia a intravenously a hiki ke waiho aku i ka mea maʻi i ka coma.

Kūlana ʻole inoa inoa inoa (mea hoʻohana ikaika):

ʻOi aku ka hopena neʻe 3 ml - mau pahu ʻāpana polū o ka lau (5) - ke kāʻei o ka cell contour (1) - nā ʻeke pepa.

Loʻo ʻia ka lāʻau lapaʻau no ka hoʻohana ʻana ma nā kūlana penei:

- na mellitus kūwaho o ka insulin (type 1),

- ka non-insulin-dependant mellitus (type 2): ke kū'ē i nā waha hypoglycemic agents, ka pale ʻana i ka paleʻana i kēia mau lāʻau (i ka wā hui pū ʻana), me nā maʻi kūʻokoʻa, hana, a me ka wā hāpai.

ʻO nā waiwai Pharmacological

ʻO ka soluble kanaka genetic engineering insulin he hana ʻokiʻoki i ka hana insulin. Ke hana nei me ka mea i loaʻa i kahi pale o nā membrane waho. I ka hoʻonui ʻana i ka hana o ka cAMP (ma nā pūpū a me nā ʻona momona) a i ʻole ka komo pololei ʻana i ka pūnaʻu, hōʻeuʻeu kēia mea paʻakikī i nā kaʻina i loko o ke kōpili, me ka hoʻokumu ʻana o kekahi mau enzymes nui (pyruvate kinase, hexokinase, glycogen synthetase a me nā mea ʻē aʻe). ʻO ka hoʻohaʻahaʻa o ka glucose o ka koko ma muli o ka hoʻonui nui o ka hoʻoulu ʻana a me ka hoʻopili ʻana e nā ʻili, he hoʻonui i ka halihali intracellular, hoʻoulu ʻia ana i ka glycogenogenesis, lipogenesis, synt synthesis, ka hōʻemi ʻana i ka hōʻemi o ka hana glucose i ka ʻā a me nā hana ʻē aʻe. Ke lawelawe ʻia ma ka subcutaniously, ulu ka hopena o ka lāʻau ma hope o ka 20 i ka 30 mau minuke, lilo ka lōʻihi ma hope o 1 a 3 mau hola a lōʻihi ka 5 i ka 8 mau hola (ma muli o ke ʻano). ʻO ka lōʻihi o ka lāʻau lapaʻau e hilinaʻi ʻia ma kahi a me ke ʻano o ka hoʻokele ʻana, ka pākana a ua hoʻolaha i nā ʻano pilikino hoʻokahi. ʻO ka piha holoʻokoʻa o ka lāʻau ka ka mea i kāpae ʻia i ka nui o ka make, kahi kahua kaʻi (ʻūhā, ʻōpū, ke kāʻei), ke ala o ka hoʻokele (subcutaneous, intramuscularly), ka pae o ka insulin i ka lāʻau lapaʻau, a me nā mea ʻē aʻe. I loko o nā kiko, lawe liʻiliʻi ʻia ka lāʻau lapaʻau. ʻAʻole ia i komo i loko o ka waiū umauma a ma o ka pāʻana placental. ʻO ka hapa nui i nā ʻeha a me ka ate, ua luku ʻia e ka insulinase. Hōʻalo ka hapalua-ola mai kekahi mau a hiki i 10 mau minuke. ʻO 30 - 80% kahi i paʻi ʻia e nā keiki.

ʻO ka maʻi mellitus type type 2 (ke kū'ē i ka lāʻau hypoglycemic oral, ke pale kino i ka lāʻau hypoglycemic oral (ke ʻano hui) no ka lipi me nā maʻi o ka maʻi me nā maʻi a me nā maʻi i mālama ʻia e ka hyperthermia, me nā hōʻeha e hiki mai ana, ka hōʻulu ʻana o ka hoʻomaʻamaʻa, keiki. me nā maʻi metabolic, ma mua o ka hoʻohuli ʻana i ka therapy me ka hoʻomākaukau ʻana i ka insulin manawa lōʻihi.

Ke ʻano no ka hoʻohana ʻana i ka insulin soluble kanaka genetically engineered a me nā dosis

ʻO ke ala o ke alakaʻi a me ka makeʻana o ka lāʻau lapaʻau ka hoʻokū ʻia hoʻokahi, i kēlā me kēia kūlana, e kau ai i ka pae o ka glucose i ke koko ma mua a i ka 1 a i ka 2 mau hola ma hope o ka pāʻina, a ke kau pū ʻia hoʻi i nā hiʻohiʻona o ka pathology a me ke ʻano o ka glucosuria. Hoʻohana ʻia ka lāʻau lapaʻau ma 15-30 mau minuke ma mua o ka pāʻina subcutaneously (ʻo ke ala o ka hoʻokele maʻamau), intravenously, intramuscularly. Me ka coma maʻi maʻi, ketoacidosis maʻi, i ka wā o ka hōʻola, intravenously a me intramuscularly. ʻO ka pinepine o ka hoʻokele o ka lāʻau lapaʻau i ka wā monotherapy he 3 mau manawa i ka lā (a hiki i ka 5-6 manawa i ka lā, inā pono). No ka pale ʻana i ka hoʻomohala ʻana o ka lipodystrophy (hypertrophy a i ʻole pagkasope o ka momona subcutaneous), pono e loli ʻia ka pūnaewele injection i kēlā me kēia manawa. ʻO ka awelika o kēlā me kēia lā he 30 - 40 PIECES, no nā keiki - 8 PIECES, a laila ma ka awelika pākahi o kēlā me kēia lā - 0.5-1-1 PIECES / kg a i ʻole 30- 40 PIEʻOMI 1-3 mau lā i ka lā, hiki paha i ka 5-6 mau manawa i ka lā. ina pono. Inā ʻoi aku ka nui o nā lā ma kēlā me kēia lā he 0.6 U / kg, a laila e lawelawe ʻia ka insulin i loko o ke ʻano o 2 a i ʻole nā mea i kaha ʻia i nā ʻāpana like ʻole o ke kino. Hiki ke hui pū me nā insulins lōʻihi. Hoʻopili ʻia ka mea hana hoʻomake me ka ethanol ma hope o ka wehe ʻana i ka pāpū alumini me kahi pulupulu maikaʻi ʻo ka syringe a me kahi ʻāpana ʻana o ka insulin e hōʻiliʻili ʻia mai ka vial.

E ʻike e nānā i ke kūleʻa o ka ʻoliʻoli ma mua o ka lawe ʻana i ka insulin mai ka vial. ʻAʻole hiki ke hoʻohana ʻia ka lāʻau lapaʻau no ke ao, ke ʻano o nā kino o nā ʻāina ʻē, ka hoʻohemo ʻana o kahi mea ma luna o ke aniani o ka hue. Pono i ka mahana o ka lāʻau lapaʻau e kūpono me ka mahana o ka lumi. I nā maʻi lēʻeha, ka hoʻāla ʻia o ka maʻi thyroid, hypopituitarism, maʻi o Addison, ka maʻi mellitus no ka maʻi maʻamau i nā poʻe he 65 a me ka hopena ʻole o ke kūaloko, pono ia e hoʻoponopono i ka dosis o insulin. ʻO nā kumu no ka hoʻomohala ʻana o ka hypoglycemia hiki i nā: ka pono o ka lāʻau, ke nānā ʻana i ka insulin, kaʻai ʻana i ka ʻai, ka maʻi ʻana, ka luaʻi, ke ʻano kino, ke hoʻololi ʻana o ka pae injection (ʻōpū, ʻūhā, ʻūhā), ka pathology e hōʻemi ai i ka pono o ka insulin (nā mākaʻi o ka ʻāʻī a me nā pūpū, also hypofunction of the pituitary gland, adrenal cortex a thyroid gland), hui pū me nā lāʻau ʻē aʻe. Hiki ke hoʻemi i nā pae koko koko i ka wā e hoʻoneʻe ana i ka mea maʻi i ka insulin manu i ka insulin kanaka. Pono ka hoʻoneʻe ʻana o ka mea maʻi i ka insulin kanaka e lawe ʻia ma lalo o ka mālama ʻana o kahi kauka a pono hoʻi i ka ʻono ʻia i ka lāʻau maʻi. Hiki i ka manaʻo o ka hypoglycemia ke hoʻohaumia i ka hiki i ka poʻe maʻi ke lawelawe i nā mīkini a me nā mīkini, a me ke komo pū ʻana me ka mākaʻi. Hiki i ka poʻe maʻi me ka maʻi diabetes e hōʻoluʻolu iho i ka hypoglycemia maʻalahi i ka ʻai ʻana i ke kō a i ʻole nā meaʻai ʻai nui i ka hāmeʻa (ʻoi aku ka maikaʻi o ka 20 me ka honu o ka kō me kāu). No ka pane ʻana i ka hihia o ka hoʻoponopono ʻana, pono ia e hōʻike i ke kauka hele e pili ana i ka hypoglycemia i hala. Ke hoʻohana nei i ka insulin hana pōkole i nā hihia i loaʻa, hiki i ka hoʻonui a hōʻemi paha i ka nui o ke kiko adipose ma ka wahi maʻi. Ke loli mau nei i ka pae injection, hiki ke pale ʻole i ka lipodystrophy. I ka wā hapai, pono e noʻonoʻo i kahi hoʻemi ʻana (ma ka 1st trimester) a i ʻole e piʻi (i ka 2 a me ka 3 o ka hoʻomaʻamaʻa) o nā koi o ka insulin. Hiki ke emi ka makemake o ka insulin i ka wā hānau. Me ka lactation, koi ʻia ka nānā ʻana o kēlā me kēia lā i mau mahina (a hiki i hoʻokau ʻia ka pono o ka insulin). ʻO nā maʻi e loaʻa ana ma mua o ka 100 IU o ka insulin i kēlā me kēia lā e pono ai ka hoʻokipa ma ka hoʻololi ʻana i ka lāʻau.

Loaʻa i nā ʻaoʻao ʻaoʻao o ka insulin e hoʻoliolo i ka ʻenehana kanaka genetic

Allergic reaksi (angioedema, urticaria, pōkole o ka hanu, ke kuni, ka hoʻohaʻahaʻa i ke koko)
ʻO ka hypoglycemia (hoʻonui nui loa, ka palau o ka ʻili, ka palu, ka haʻalulu, ka palpitations, ka pōloli, ka hopohopo, ke kaumaha, ka paresthesia i loko o ka waha, ka hiamoe, ke poʻo, ka ʻōpū, ka hopohopo, hopohopo, ka makaʻu, ka huhū, ka nele o ka neʻe, ka ʻano ʻole kamaʻilio waha), hypoglycemic coma, naʻaupō o ka naʻau (a hiki i ke kūkulu ʻana i ka coma a me ka precomatosis), ka waikika diabetes a me ka hyperglycemia (me nā inikina i hala, nā ʻōkuhi liʻiliʻi, nā meaʻai maikaʻi ʻole i ka maʻi, a me nā maʻi oradicum): makewai, ʻeha, ka hyperemia o ka maka, ka hoʻohaʻahaʻa ʻawa, ka hoʻoweliweli ʻana o ka ʻike manuahi (ma ka hoʻomaka ʻana o ka mālama ʻana), ka ʻeha, ka hyperemia a me ka lipodystrophy (hypertrophy a i ka atrophy of subcutaneous adipose tissue) ma ka pūnaewele injection, hoʻonui ʻia i ka hapa o nā anti-insulin antiodies me ka hoʻonui hou aʻe i ka glycemia. i ʻole ke alapine o ka maʻi immunological me ka insulin kanaka, ma ka hoʻomaka ʻana o ka lāʻau lapaʻau - hoʻālaʻi ʻia i ka maʻi a me ka edema.

Ke keu

Hoʻopili pū me nā lāʻau ʻē aʻe

ʻO ka ʻikepili ma ka ʻaoʻao ka mea i hōʻoia ʻia e ka mea hoʻokaumaha ʻo Vasilieva E.I.

Pehea e koho ai i ka analog kūpono
I loko o ka pharmacology, hoʻokaʻawale pinepine nā lāʻau i nā ʻ synlelo a me nā kikowaena. Hoʻokomo ʻia i ke ʻano o nā like o nā ʻano like ʻole i ke ʻano he hopena therapeutic ma ke kino. Ke hoʻohālikelike nei nā analogs i nā lāʻau lapaʻau e pili ana i nā ʻano like like ʻole, akā no ka mālama ʻana i nā maʻi like.

ʻO nā ʻokoʻa ma waena o nā maʻi a me nā maʻi bacterial
Hoʻopilikia ʻia nā maʻi maʻi e nā maʻi, nā maʻi, nā fungi a me ka protozoa. ʻO ke ʻano o nā maʻi i hoʻomake ʻia e nā maʻi a me nā maʻi like ʻole. Eia nō naʻe, ka hoʻokaʻawale i ke kumu o ka maʻi i ke koho e kūpono i ke ʻano kūpono e kōkua ai i ka hoʻokē ʻana i ka malaise a ʻaʻole ʻoe e hōʻino i ke keiki.

ʻO nā maʻi āpau ke kumu o ke anuanu pinepine
ʻIke kekahi poʻe i kahi kūlana i kahi pinepine ke keiki a a lōʻihi no ka manawa anuanu. Lawe nā mākua iā ia i nā kauka, lawe i nā hoʻokolohua, lawe i nā lāʻau lapaʻau, a ma muli o ke ʻano, ua hoʻopaʻa inoa ʻia ke keiki me ke keiki e like me ka maʻi nui. ʻAʻole i ʻike ʻia nā kumu maoli o nā maʻi ʻeha pinepine.

Urology: hana maʻi urethritis chlamydial
Loaʻa pinepine ʻia Chlamydial urethritis ma ka hana o kahi urologist. Hoʻokumu ʻia e ka intracellular parasite Chlamidia trachomatis, aia nō nā waiwai o nā huakini a me nā maʻi like, ua makemake pinepine i ka antibiotic therapy regimens no ka maʻi antibacterial. Hiki iā ia ke hana i ka mumū ʻole o ka maʻi o ka urethra i nā kāne a me nā wahine.

Soluble kanaka genetic engineering insulin: nā ʻōlelo no ka hoʻohana ʻana

Hoʻolālā ʻia ka ʻenekini hana genetic no ka insulin insulin i:

ʻ Ilelo I ke ʻano type type II: i ka wā i hiki ʻole ke mālama i ka lāʻau hypoglycemic oral a me ko lākou ʻano
Maʻi molaʻi
Coma
Diabetes i ka wā hāpai (inā ʻaʻole kōkua ke ʻano ʻoihana meaʻai)
No ka hoʻohana lohi i ka maʻi maʻi ma mua o nā kuʻuna o nā pathology infectious me ka huʻipiʻi kipi, i ka hoʻomākaukau ʻana no ka hōʻemi ʻana, nā mea hōʻeha, ka hana, ka maʻi metabolic, a i ka wā hoʻi e hoʻololi i nā insulins lohi.

ʻO ke kinona insulin mea he ʻāpana o nā lāʻau lapaʻau mai nā mea hana like, no laila ua ʻokoʻa nā mea kōkua.

Kūʻai: 10 amp. 1 ml kēlā - mai 177 kaomi., Pahu pahu 5 pcs. 3 ml -

1 ml o nā pona he:

Mea waiwai: 100 IU
Nā kumuwaiwai hou: zinc chloride, glycerol, sodium hydroxide (a i ʻole hydrochloric acid), ka wai.

Ke hōʻike nei i nā kinaka ma kahi kūlana o kahi wai kūlohelohe piha ʻole ʻole no ka hoʻohana makua. Hoʻopili ʻia i nā ampoules, pen-syringes, nā hue.

ʻO nā mea hana pōkole no ka hoʻohana ʻana me ke ʻano lā i hilinaʻi ʻia me ka mahele like ʻole o ka maʻi type a i ʻole ka lā 2. Ma hope o ke kū ʻana ʻana, e hana me ka receptors pilikino i ka membrane cell, ka hopena ma ke ʻano o ka hoʻopihapiha insulin-receptor, e hoʻohuli ana i ka synthesis o cAMP, ka kahe o nā kaʻina o loko i loko o ka pū, me ke komo ʻana o ka nui o nā huina.

ʻO ka emi ʻana o ke glycemia ma muli o ka hoʻonui ʻana i ka halihali, hoʻohana i ka hoʻohana nui ʻana, ka synthesis synt protein wikiwiki, a me ka hoʻolimalima i ka pae ʻana o ka glucose ma o ke ake.

Ke hoʻomohala ʻia nei ka hopena o ka hopena hypoglycemic ma hope o ke kēkē ʻana ma hope o 15-30 mau minuke, hōʻea i nā waiwai koʻikoʻi ma hope o nā hola 1-3 a mau loa, e pili ana i ka nui o ka nui o ka hoʻokaʻina ʻana. ʻO ka lōʻihi o ka hana o ke ʻano ʻenehana genetically i hoʻopaʻa ʻia e ka nui, ka wahi a me nā ʻano o ka hoʻokele, a me nā ʻano o ke kino o ka mea maʻi.

Kūleʻa ka mea i loko o nā ʻili, ʻaʻole i hele i ka plasenta a me ka waiū. E wāwahi ia i ka nui o ka ʻāʻī, nā keiki ma lalo o ka hopena o ka insulinase. Hoʻokuʻu ʻia ka urine mai ke kino.

Kūkā ʻia nā inikini insulin manuahi kanaka i lalo o ka ʻili a i ʻole o ka lumen o nā veins. Koho ʻia ka nui o ka waihona ma muli o ke ʻano glycemic level. ʻO ka pono maʻamau o kēlā me kēia lā no 0.3-1 IU. I nā maʻi me ka pale ʻana i ka insulin, ʻoi aku ke kiʻekiʻe, a ma nā poʻe me ka huna iki o ka waiwai, e haʻahaʻa ʻia.

Hoʻokomo ʻia kahi maʻi ma ka hapalua hola ma mua o ka ʻai ʻana a i ʻole hana ʻai i nā huahana momona. No nā injections subcutaneous, koho i ka ʻaoʻao ma ka ʻaoʻao mua o ka ʻōpū, a me ka ʻūhā luna o luna, nā ʻūhā a i ʻole mea nui i ka brachial brachial. No nā pilikia wikiwiki, ʻo ka mea nui e hoʻololi koke i ka pae o ka glycemia, ʻoi aku ka maikaʻi o ka ʻili i loko o ka ʻōpū, ʻoiai ʻo ka insulin i kēia hihia ke wikiwiki ʻo ia.

Inā hoʻokomo ʻia ka lāʻau lapaʻau i loko o ka ʻili o ka ʻili, a laila ma kēia hihia ke kū kaʻu o ka komo ʻana i ka io. I mea e pale ai i ka puka ʻana o nā lāʻau lapaʻau, ua ʻōlelo ʻia ʻaʻole e huki i ka nuku no 6-10 mau kekona. No ka hoʻonāukiuki, pono ʻoe e hoʻohana i kahi ʻāina hou i kēlā me kēia manawa e pale i ka hōʻeha kino ʻana i ka dermis a me ka subcutaneous tissue.

Ke koi nei i ka vein e ʻike i ka ʻike kūikawā a me ka ʻike nui, no laila, ʻae ʻia nā ʻano hana i nā loea lapaʻau wale nō.

Ma mua o ke ana ʻana i ka ʻaiʻana o ka inikini kūloko genetically mai loko mai o kahi vial a ampoule paha, pono ʻoe e hōʻoia i ka ka ʻoli ʻana o ka hoʻonā. Inā loaʻa nā mana i loko o ia mea, ke hoʻopiʻi nei a i ʻole kahi pahu me ka lāʻau lapaʻau e ʻuke ʻia, e ʻoki ai a i ʻole hoʻi i loko, a laila ua manaʻo ʻia ka lāʻau lapaʻau ʻaʻole kūpono no ka hoʻokele. Pono ka hoʻolilo ʻia e like me nā rula i ʻae ʻia.

Ma mua o ka hoʻonāukiuki, pono ʻoe e hoʻomālamalama i ka lāʻau lapaʻau ma ke ala kūlohelohe no ka like o kona pāhana me ke anuanu lumi.

Pono e hoʻololi ʻia ka dosage inā he maʻi maʻi ʻo ka mea maʻi a i ʻole kahi thyroid dysfunction. Pono pono ka hoʻoponopono ʻana i ka maʻi o Addison, ka wā kiʻekiʻe, ka ulu ʻana o ka pituitary, nā pilikia ʻole i ka hopena.

ʻAʻole ʻae ʻia ka hypoglycemia. ʻO mua ka hoʻomohala ʻia e ka hoʻomaka ʻana o ka nui o ka insulin, ke kūleʻa ʻana i ka lāʻau lapaʻau pono ʻole, ka ʻaihue ʻana i ka ʻai, ka luaʻi ʻana i ka maʻi ʻaʻai, ke ʻano kūlohelohe, ke ʻano kūlohelohe, nā ʻōpū a me nā ʻano ʻē aʻe o nā mākaukau, nā hana adrenal, hui pū me nā lāʻau ʻē aʻe. Eia kekahi, e hoʻohaʻahaʻa paha ka pae o ka glycemia ma hope o ka hoʻololi ʻana i ke kahawai maʻi, ka neʻe ʻana mai ka insulin holoholona. I ka hopena hope loa, pono e hoʻoneʻe ʻia ka hoʻololi ʻana i ke ʻano o ke kanaka no nā maʻi olakino. Hāʻawi ʻia ka hoʻololi ʻana i ka lāʻau lapaʻau iho.

Ile insulin isulin

HAAWINA: Hoʻomākaukau homre pancreatic, insulins medium-act, kanaka hana ʻenehana

Rp .: Insulini isophani 5ml (100ME)

S .: 20 ME subcutaneously 2 mau manawa i ka lā.

MEAHUA: Hoʻokumu i kahi mea hoʻonaninani insulin i ka membrane, hoʻonui i ka cAMP, hoʻoulu i ka synthesis o nā enzymes (hexokinase, etc.). ʻO ka emi ʻana o ke kaohi o ka glucose i loko o ke koko ma muli o ka hoʻonui o kāna kaomi intracellular (hoʻopili ʻia e nā ʻāpana), hoʻoulu ʻia i nā lipogenesis, glycogenogenesis, a me ka hoʻolilo ʻana i ka hana o ka glucose i ka ate (e hoʻoneʻe i ka wāwahi o glycogen).

KAUANA: ʻO T1DM, T2DM: ke kū'ē o ke kū'ē i ka maʻi o ka waha, waena o waena, T2DM i nā wahine hāpai.

KOHONUI: HS, hypoglycemia.

KID:Hoʻomaʻaʻa i ka U hoʻololi: hypoglycemia (ka palapale o ka ʻili, hoʻonui nui ʻia, palpitations, pā nui, pōloli, ʻūhā, paresthesia i loko o ka waha, gb, comog hypoglycemic).Nā maʻi kūwaha: ʻāwili ʻili, ka polema o Quincke. Nā ʻili: ka ʻōpū ʻana, nā hewa i hoʻihoʻi ʻia. Nā kūloko kūloko: ʻo ka maʻiemia, ke kuʻi a me ke kuʻe ʻana i ka wahi i ʻōlelo ʻia, me ka hoʻohana lōʻihi - lipodystrophy ma ka wahi ʻōlelo.

HAAWINA: nā hana antidiabetic waha līlū, ka pale ʻana o ka pale i ka hoʻoliʻi a me nā mākaʻi, biguanides

Rp .: Tabl. Metformini 0,5

S .: 1 papa 2 (a ʻole) 1 mau manawa i kahi lā (i ke ahiahi) ma hope o ka ʻai.

MEAHUA: hoʻonui i ka naʻau o ka insulin, hoʻoulu ʻia i ka hopu ʻana o ka glucose ma o ka mākala, ua hōʻeuʻeu i ka glycolysis anaerobic, hoʻemi i ka hoʻoliʻi glucose i loko o nā ʻāpana a hoʻoulu i ka momona, hoʻohaʻahaʻa ka glucagon i ke koko a me LDL, cholesterol, a me ka triglycerides, a hoʻoemi i ka momona a me ka ʻai ka kaumaha kino kino.

KAUANA: T2DM (kūikawā no ka momona) me ka hana ʻole o ka meaʻai.

KOHONUI: HF, renal / ate / iha / hanu / puuwai hōʻeha, hōʻeuʻeu ka naʻau, anemia, puʻuwai, maʻi maʻi hopohopo, ʻalowa, metabolic acidosis, hapai, lactation.

KID: GIT: i ka hoʻomaka - anorexia, ʻeha, ʻōpū, ka luaʻi, ʻōlelo huakaʻi, ka ʻōpū o ka ʻōpū, ʻōpū metallic i loko o ka waha. CCC: anemia megaloblastic. Hoʻohui: hypoglycemia, lactic acidosis (nāwaliwali, ke kaumaha nei, hypotension, kū'ē bradyarrhythmia, ʻeha hanu, ʻeha puʻuwai, myalgia, hypothermia). ʻIli: ʻohiʻe, dermatitis.