ʻO nā maʻi neʻe intestinal kahi mea kaua hou e kūʻē i ka maʻi diabetes type 2

Hiki i ka huapalapala i loko o ka pale ke pale i ka maʻi diabetes. Hōʻike ʻia kēia e nā hopena o kahi noiʻi hou i hana ʻia ma ke University of Eastern Finland.

Ka pale wai sololo indolpropionic kiʻekiʻe e pale aku ai i ka maʻi diabetes type 2. ʻO kēia waikawa he metala i hana ʻia e ka huina a me nā huahana a hoʻonui ʻia e nā meaʻai momona. Wahi a nā mea noiʻi, hāʻawi ka ʻike i kahi ʻike hou o ka hana o ka huina o ka ʻōpū ma ka hoʻopili ʻana ma waena o ka mea ʻai, a me ka hoʻokalakupua a me ka olakino.

Ua hōʻike pū ʻia ka noiʻi ʻana i kekahi mau metabolite hou o ka lipid kiʻekiʻe, ka ʻike nui ʻana i hoʻopili ʻia me ka kū hou o ka pale ʻana i ka insulin a me kahi hōʻemi o ka hoʻomohala ʻana i ka maʻi diabetes. Ua pili pū kekahi o nā mea kuhi me kēia momona i ka momona: ʻo ka haʻahaʻa o ka nui o ka momona saturated i loko o ka meaʻai, ʻoi aku ka kiʻekiʻe o ka ulu ʻana o kēia mau metabolites. E like me ka indolpropionic acid, ke ʻike nui ʻana hoʻi o kēia mau metabolid ka lipid e pale aku e hōʻemi ʻia i ka ʻaihue haʻahaʻa.

"Ua hoʻopili mua ʻia ka noiʻi mua i nā maʻi pākeke i ka hopena o ka maʻi ma ka poʻe momona." Hōʻike kā mākou mau hopena ʻo ka hoʻoneʻe indolepropionic kekahi o nā mea e hoʻopili ai i ka hopena palekana o ka mālama ʻana i ka meaʻai a me nā maʻi o ka ʻōpū, "wahi a ka mea noiʻi hoʻonaʻauao ʻo Katie Hanhineva mai ke University of Eastern Finland.

ʻO ka ʻike pololei ʻana i nā huakini o ka pāpana he hana paʻakikī, no laila, ka ʻike ʻana i nā metabolites i hoʻoili ʻia e nā huina o ka ʻawaʻawa paha i ala kūpono loa no ka nānā ʻana i ke kuleana o nā huina o loko o ka pathogenesis o, no ka laʻana, maʻi diabetes.

Pākuʻi a me ka maʻi diabetes

Aia ka ʻōpū o ke kanaka i nā piliona o nā maʻi like ʻole - kekahi maikaʻi no ke olakino a me kekahi hewa. Ma mua ua manaʻoʻiʻo ia he mea pono ia no ka lawelawe kūpono o ka pēpē ʻana, akā naʻe, e like me ka ʻike i kēia manawa, ua pili nā maʻi o ka pehu i mea kokoke i nā ʻōnaehana o ko mākou kino.

Ua ʻike mua ʻia ʻo nā kānaka e ʻai i nā fiber hou aku i loaʻa i ka maʻi diabetes lā 2. ʻO kahi papaʻai momona i ka momona o ka mea kanu e kōkua i ka hoʻohaʻahaʻa ʻana i ka glucose o ka wikiwiki i nā kānaka i loaʻa ka maʻi maʻi. Akā, no nā kānakaʻokoʻa ʻokoʻa ka hopena o ka meaʻai like.

ʻO kēia manawa, ua aʻo ʻia ʻo Liping Zhao, ke loio ma G. Rutgers State University of New Jersey ma New Jersey, i ka pilina ma waena o ka fib, bacteria bacteria, a me ka maʻi maʻi maʻi. Makemake ʻo ia e hoʻomaopopo pehea e pili ai ka pāʻai a ka momona o ka lipine i ka ʻōpū o ka ʻōpū a hōʻemi i nā hōʻailona o ka maʻi maʻi, a i ka wā e wehewehe ʻia ai kēia ʻano, e aʻo pehea e hoʻomohala ai i kahi papa no ka poʻe me ka maʻi type 2. I ka hoʻomaka mua o Malaki, ua paʻi ʻia nā hopena o kēia haʻawina makahiki 6 i loko o ka ʻAmelika Pūnaewele ʻepekema.

Nui nā ʻano o nā huelo o ka ʻōpū e hoʻohuli ai i nā kalaiwa i nā momona momona pōkole, ʻo ia hoʻi ka acetate, butyrate, a me ka propionate. Ke kōkua nei kēia mau momona momona i ka mālama ʻana i nā wahī e laina i ka ʻōpū, hoʻemi i ka hana ʻino i loko ona a hoʻoponopono i ka pōloli.

Ua ʻike mua nā ʻepekema i kahi pilina ma waena o nā haʻahaʻa haʻahaʻa o nā momona momona a me nā maʻi diabetes, ma waena o nā kūlana ʻē aʻe. Ua māhele ʻia nā mea noiʻi o Kauka Zhao i 2 mau pūʻulu a hahai i ʻelua mau mea ʻai ʻē aʻe. Ua hahai kekahi pūʻulu i nā kulekele meaʻai maʻamau, a ua ukali kekahi i ia, akā me ka hoʻopili ʻana o ka nui o ka mea momona o nā meaʻai, me nā koina a pau a me nā lāʻau lapaʻau kuʻuna.

He aha nā mea kanu nui?

Ma hope o 12 mau pule o ka papaʻai, ua komo nā mea i hui i ka hui, kahi i kau ai ka manaʻo nui ma ka momona, a hoʻemi nui ʻia ka pae o ka glucose i loko o ke koko no 3 mau mahina. ʻO ka wikiwiki o ko lākou kaila wikiwiki ka emi ʻana o ka wikiwiki, a ua nalowale lākou i nā koina keu he nui ma mua o ka poʻe i ka pūʻulu.

A laila ua hoʻomaka pono ʻo Kauka Zhao a me nā hoa hana i nā ʻano like ʻole o ke ʻano o nā huakini. ʻO nā 141 mau palaka o nā maʻi o nā palupalu e hiki ai ke hoʻopuka i nā momona momona pōkole, ʻo 15 wale nō e ulu me ka hoʻopau ʻana o nā kinipona pā. No laila ua hele mai nā ʻepekema i ka hopena o kā lākou ulu ʻana e pili ana i nā loli maikaʻi i nā mea ola o nā maʻi.

"Ke hōʻike nei kā mākou haʻawina ʻo ka huaʻai o nā mea kanu e hānai i kēia pūʻulu o nā huakini o ka peʻa hiki ke lilo i hapa nui o kaʻai a me ka mālama ʻana i nā poʻe me ka maʻi type 2," wahi a Kauka Zhao.

I ka lilo ʻana o kēia mau bakuna i nā kūmole o ka flinal intestinal, hoʻonui lākou i nā pae o ka waikiki pōkole pōkole o ka butyrate a me ka acetate. Hoʻokumu kēia mau pūhui i kahi wai iʻoi aku ka wai i loko o nā wahina, a e hōʻemi ana i ka nui o nā koina bakela i makemake ʻole ʻia, a me kēia, ke alakaʻi nei i ka hoʻonui ʻana o ka hana insulin a mālama pono i ka pae o ka glucose o ke koko.

Ke waiho nei kēia mau ʻike hou i ke kumu no ka hoʻomohala ʻana i nā ʻaneki hou e hiki ai ke kōkua i ka poʻe me ka maʻi diabetes e mālama i ko lākou kūlana ma o ka meaʻai. ʻO ia ke ʻano maʻalahi a kūpono ʻole i ka pale ʻana i ka maʻa e wehe ai i nā kūlana kupaianaha no ke hoʻololi ʻana i ke ʻano o ke ola o nā maʻi.

Ua pili nā ʻepekema mai ke Kulanui o Queensland Australia i nā maʻi o ka ʻōpū ma ka hoʻomohala ʻana i ke ʻano maʻi type 1

Hiki ke kōkua i nā mea maʻi me ka diabetes type 1 ke kōkua ʻana i ka hoʻihoʻi ʻana i ka ʻano o ka microflora pono o ka ʻōpū.

E like me kahi hōʻike hou e hōʻike nei, ʻo ka huli ʻana ʻana i ka microbiota kūikawā i loko o ka huehue kekahi ala e pale ai i ka maʻi diabetes type 1. Ua ʻike ʻia nā mea noiʻi mai ke Kulanui o Kuʻinaka ma Australia i nā loli i ka microbiota gut i loko o nā rodents a me nā poʻe e koi ana i ka maʻi diabetes type 1.

No ka ʻike hou aku e pili ana i ka loiloi, ʻike ʻia:

ʻAtikala Microbiome

Ua kākau ʻo Kauka Dr. Emma Hamilton-Williams o ke Institute for Translational Studies ma ke Kulanui o Queensland a me kāna mau hoa hana i kā lākou ʻike ʻana e hōʻike ana i ka huli ʻana i ka microbiota intestinal paha hiki ke pale aku i ka maʻi diabetes type 1.

INE INFESTINAL MICROFLORA MA ʻĀTOU 2 DIABETES

ʻAʻole hōʻiliʻili ka pancreas i ka nui o ka insulin, ʻaʻole i hoʻomaʻamaʻa ʻia ka insulin.

ʻO ka maʻi mellitus type 2 he maʻi metabola e hōʻike pono ana iā ia iho he mea hoʻokūkū o ka pauku e kaohi ana i ka paʻakai. ʻAʻole hana ke kino i ka nui o ka insulin no ka hana kūpono, ʻaʻole paha nā mea i loko o ke kino e pane i ka insulin (kū'ē a insulin a i ʻole kū i ka insulin. Ma kahi o 90% o nā maʻi maʻi maʻi āpau ma ka honua holoʻokoʻa he ʻano type diabetes 2. Ma muli o ka loaʻa ʻana o ka kū'ē o ka insulin, ʻo ia hoʻi, ʻo ka pale ʻana o nā selela o ke kino i kēia hormone, ulu ka hyperglycemia (he nui ka piʻi ʻana o ka glucose i loko o ke koko). Ma nā huaʻōlelo maʻalahi, ke ʻano maʻamau o ke kino ka nui o ka insulin a me ka nui o ka glucose, ʻaʻole i hiki i kekahi mau kumu ke komo i loko o nā hale.

Ua hōʻoia mua nā kānaka ʻepekema i ke kuleana o ka microbiota i ka kū ʻana o ka insulin i ka hoʻāʻo ʻana ma o ka hoʻololi ʻana i ka microflora mai kahi hāʻawi ola kino i ka mea maʻi me ka maʻi diabetes type 2. I ka hopena o ka hoʻokolohua, ua hoʻonui ʻia nā mea maʻi me ka ʻike ʻana i ka insulin ma o nā hebedoma.

Nā mea kikoʻī hou aʻe:

Ke kānalua ʻole nei i ka ʻoiaʻiʻo o nā hopena biochemical e kū mai ana i loko o ko mākou kino a hoʻoholo maoli i kā mākou olakino e hilinaʻi pololei ana i ke ʻano o ka gastrointestinal tract a me ka hoʻopili ʻana o kāna microflora me nā sela o ko mākou kino. Hāʻawi ia i nā probiotics i nā waiwai immunomodulating, ua kōkua lākou i ka hana maʻamau o ka microflora o ka gastrointestinal tract, ʻo ia hoʻi No ka hoʻemi ʻana o ke kaumaha nui o ke kino, ʻo ia ka mea e hoʻonui ai i ka hiki i ka hoʻomohala ʻana i ka maʻi diabetes, hiki ke noʻonoʻo ʻia ka hoʻohana pono ʻana o nā huahana meaʻai probiotic a me ka hoʻokomo ʻana o ka probiotics i kekahi o nā mea hoʻohiki e mālama i ka mālama ʻana a me ka mālama ʻana i ka maʻi mellitus.

E LOAʻO KA VELETABLE CELL E pale i ka ORGANISM mai SUGAR DIABETES

Me ke kōkua o ka micro microflora, e hoʻohuli ʻia ka momona o ka ʻai i nā momona momona, a laila e hoʻohana nā ʻōpū i ka synthesize i ko lākou iho glucose. Hoʻomaʻamaʻa ka mea hope loa i mea e ʻike ai i ka lolo o ka pono e pale i ka manaʻo o ka pōloli, hoʻonui i nā kumukūʻai o ka ikehu a hoʻemi i ka hoʻokuʻu ʻana o ke kō mai ka lolo.

Ua lohe paha ʻoe e pili ana i nā pono o ke fiber, pololei? E pili ana i ka momona meaʻai nui e pale ai iā mākou mai ka momona a me ka maʻi maʻi. Nui nā hua i kēia mau lau a me nā hua, akā ʻaʻole hiki ke hoʻokaʻawale nā ​​ʻōpū iā lākou, a no laila wikiwiki ka microflora i kāna kōkua. Hoʻomaopopo ka hopena metabolic maikaʻi a me ka physiological o ke kahe i ka nui o nā hoʻokolohua: i hōʻiliʻili ʻia nā holoholona ma kēia meaʻai a emi iho ka momona, a ua hōʻemi ʻia ko lākou kuʻuna o ka hoʻomohala ʻana i ka maʻi diabetes. Eia naʻe, ʻaʻole hiki iā mākou ke ʻōlelo maopopo ke maopopo iā mākou ke ʻano maoli o kēia mau ʻano. Ua ʻike ʻia e hoʻowalewale ʻia e nā maʻi o ka palu me ka hoʻokumu ʻana o nā pōkoki momona pōkole, propionic a butyric, a laila e komo i loko o ke koko. Nā ʻepekema ʻepekema mai ka National Center for Scientific Research (CNRS) ma Farani ua ʻōlelo e pili ana kēia mau waikena i ka syntypose glucose ulu. Hiki i nā mea puna ona synthesize glucose, hoʻolei i loko o ke koko ma waena o ka pāʻina a me ka pō. ʻO ia ka mea e pono ai no ka: huki nā gula i nā waihona mea hoʻopili veins, e hōʻiliʻili i ke koko mai loko mai o nā ʻōpū, a hoʻouna kēia mau mea hāʻawi i kahi hōʻailona kūpono i ka lolo. Pane ka ʻākala ma o ke kīpē ʻana i ka pōloli, e hoʻonui ana i ka ʻai o ka ʻāpana huna a hoʻomakei i ka hāhū e hoʻolohi i ka mahuahua glucose.

ʻO ia, ma muli o kahi hapa liʻiliʻi o ka glucose mai ka ʻawaʻawa, ke hoʻokuʻu ʻia ka hoʻokuʻu ʻana o ka glucose mai ka ate, a ua hana ʻia nā hana kūʻē i ka hoʻopio ʻana o ka hou - pono ʻole a ʻehā hoʻi - nā calorie.

Ka mea i hooliiliia o ka hana o nā huaʻehā i loko o nā wahi o ke aʻalolo e pili ana i ka synthesis glucose i kau ʻia i kēlā mau fibers, a me nā waikawa propionic a butyric. Hoʻohana ka ʻōpala i ka waikawa propionic ma ke ʻano he kumu waiwai no ka synthesis glucose. ʻO nā moʻoki i hoʻoulu ʻia i ka nui o nā momona a me nā mea kākoi e loaʻa ana i ka mea kaupaona a ua hōʻemi paha lākou i ka maʻi maʻamau inā e ʻai lākou i ka momona me ka momona a me ke kō. I ka manawa like, ua hoʻonui ʻia lākou i ka naʻau i ka insulin (ʻo ia hoʻi, e ʻike ʻoe, e ʻoki ana me ka maʻi maʻamau ʻo ka maʻi 2.

Kahakaha: pono ia e hoʻomaopopo i kēlāhuehae propionicheʻo kekahi o nā hua mea nui o nā huela o ka propionic acid, kahi, me ka propionates a me nā propiocins, hiki ke hoʻokaʻawale i ka ulu ʻana o nā microorganisms pathogenic. A, eia, hoʻohālikelike ʻia ka acid butyric e clostridia, kahi mau ʻāpana o ka microflora maʻamau o ke kanaka.

Ma ka hoʻokolohua ʻē aʻe, ua hoʻohana ʻia nā mau kiole i hiki ai i ke kāpili i ke kūmole i loko o ka pūpū. I kēia hihia, ʻaʻohe hopena o ko kāua meaʻai ʻana. ʻO ia, ʻike ʻia ke kaulahao: e ʻai mākou i ka lepa, nā mikoleka ka hana ʻana iā ia nā momona momona, a laila hiki i nā iwi ʻoka i hiki ke hoʻohana no ka synthesize i ka regulator glucose. Pono kēia glucose i kaupena ʻia i ko mākou makemake kūpono e hoʻoinu i kahi mea i ka pō, a me ka mālama i ka kaulike kūpono o ka glucose i loko o ke kino.

Ma kahi ʻē aʻe, eia kekahi ʻōlelo'ē aʻe e makemake i ka ʻoiaʻiʻo e pono ai mākou i ka microflora o ka ʻupena e hiki ai ke noho olakino, a ua loaʻa kēia hopena i kahi ʻano biochemical ʻano pono. Ma kahi kikoʻī, hiki nō, me ke kōkua o kēia kaula biochemical, hiki ke hiki mai i ka wā e hiki mai ana me ka hana ʻana i nā ʻano maikaʻi ʻole ke alakaʻi i kā mākou huelo a me ka maʻi diabetes. / Kūpono ʻia nā hualoaʻa ma ke kauā Cell.

* No ka hana pono o nā waiwai o nā microorganisms probiotic i ka hana ʻana i nā lāʻau lapaʻau hou no ka mālama ʻana a me ka pale ʻana o ka maʻi ʻohiʻipiʻi a me ka maʻi diabetes, ʻike i ka wehewehe ʻana no ka probiotic "Bifikardio":

E ola kino!

KOMIKALOKA MANA O PROBIOTIC DRUGS

He aha kaʻu e hana ai?

I ka wā hele, hiki iā ʻoe ke nānā i kāu ʻai ponoʻī e kūkākūkā me kāu kauka pehea e hoʻomau ai iā ia me ka fiber. ʻO nā meaʻai e ʻae ʻia no ka maʻi maʻi a me ka momona ma ka momona ka mea, i ka laʻana: nā raspberry, nā keʻokeʻo keʻokeʻo hou, nā lau kanu hou, nā kūmato hou, nā pākī i hoʻolapalapa a me nā pua Brussels, avocados, buckwheat, oatmeal. Me ka nui o ka nui, hiki iā ʻoe ke ʻai i ka pī, nā ʻalemona, nā pistachios (ʻaʻohe paʻakai a me ke kō, ʻoi aku hoʻi), me ka lentil a me nā pīni, a, ʻoiaʻiʻo, ka palaoa huakai a pau mai ka wholemeal a me ka bran.