Pehea e hoʻohana ai i ka lāʻau lapaʻau Neyrolipon?

Ka makua, i loko o 300 a me 600 mg: nā maʻi diabetes a me nā waiʻona polyneuropathy.

I loko o 12 a me 25 mg: ka momona momona, cirrhosis, hepatitis maʻi, hepatitis A, hoʻomoʻa (me ka paʻakai o nā metala koʻikoʻi), ka mea make me ka palaka pale, hyperlipidemia (me ka hoʻomohala ʻana i ka atherosclerosis coronary - mālama i ka mālama a me ka hoʻopiʻi. )

Nā hopena hopena

Mai ka hānaʻi ʻana o ka hana ʻana: i ka wā i lawe ʻia ai i ke alo - nausea, luaʻi, ka ʻōpū o ka ʻōpū, ʻeha.

He maʻi kūlohelohe: hāpala o ka ʻili, mālama, urticaria, hoʻihoʻi anaphylactic.

Nā kumuwaiwai: hōʻehaʻeha, hoʻonaninani ka glucose glucose (hypoglycemia), me ka wikiwiki iv - ka wā pōkole a paʻakikī paha ka hanu ʻana, hoʻonui i ka hoʻonaninani intracranial, hoʻokūpono, diplopia, pinpoint hemorrhages i ka pākuʻi a me ka mucous membranes a me ka makemake e hoʻāhu ʻia (ma muli o ka hana o ka platelet heʻelima. )

Capsule Neurolipon (Neurolipon)

Nā ʻōkuhi no ka hoʻohana lāʻau olakino

• Nā hōʻailona no ka hoʻohana ʻana
• E hoʻokuʻu i ke ʻano
• ʻO ka Pharmacodynamics o ka lāʻau
• ʻO ka Pharmacokinetics o ka lāʻau
• Hoʻohana i ka wā hāpai
• Nā Hoʻohui
• Nā hopena hopena
• ʻLoe a me ke kākele
• Ke keu
• ʻO ka pilina me nā lāʻau lapaʻau ʻē aʻe
• Hoʻomaʻamaʻa no ka hoʻohana
• Nā kūlana mālama
• ʻO ka lā kau

Nosological ʻano papa (ICD-10)

ʻLoe a me ke kākele

Ma ka /. ʻO nā pākeke ma kahi maʻi o 600 mg / lā. E komo mālie - ʻaʻole oi aku ma mua o 50 mg / min o ka waihuna thioctic (1.7 ml o ka hoʻonāʻau no ka infusion).

Pono ka lāʻau e mālama ʻia e ka infusion me ka hopena o ka sodium klorida 0.9% i hoʻokahi lā (600 mg o ka lāʻau i hui pū ʻia me 50-250 ml o kahi hopena o ka sodium klorida 0.9%). I nā pilikia koʻikoʻi, hiki ke hoʻokele a hiki i 1200 mg. Pono e pale ʻia nā hoʻonāpili infusion mai ka mālamalama e uhi iā lākou me nā pale pale māmā.

ʻO ke ala no ka mālama ʻana mai 2 a 4 wiki. Ma hope o kēlā, huli lākou i ka mālama mālama ʻana i nā maʻi mālama i nā ʻano wai thioctic no ka hoʻokūkū waha ma kahi maʻi o 300-600 mg / lā no 1-3 mau mahina. Ke hoʻohui i ka hopena o ka lāʻau lapaʻau, ʻo ia ka mea e hōʻike ʻia ka papa o ka lāʻau me ka lāʻau Neyrolipon e loaʻa i 2 mau manawa i ka makahiki.

ʻAʻole paʻa i ka pono a me ka palekana o ka lāʻau i nā keiki.

E hoʻokuʻu i ke ʻano

Kūleʻa i ka hoʻonā no ka infusion, 30 mg / ml. I nā pahu pahu aniani, me ke apo wāwahi a kī hōʻaha paha, 10 a 20 ml paha.

5 a 10 amp. pū me kahi ʻeke o ke kiʻi ʻoniʻoni PE peʻa ʻole ʻole i loko o kahi ʻeke pepa me nā liners corrugated.

5 pā. i kahi pahu kiʻi o PVC. 1 a i 2 paha bl. me nā ampoules me kahi ʻeke o nā kiʻi PE ʻeleʻele ʻole i ʻole e ʻole ma kahi ʻeke pepa.

Mea hana

PJSC "Pahu". 04080, Ukraine, Kiev, st. Frunze, 63.

Tel./fax: (8-10-38-044) 417-10-55, 417-60-49.

Ua ʻae ka hui i nā ʻōlelo pane mai nā mea kūʻai aku: ke kikowaena luna o ka lehulehu Farmak JSC ma Lūkia: 121357, Moscow, ul. Kutuzovsky Kumukuai, 65.

Tel .: (495) 440-07-58, (495) 440-34-45.

Nā Hoʻohui

Hypersensitivity i nā ʻāpana o ka lāʻau.

ʻO ke kahawai, ʻo ka wā o ke umauma (ʻike me ka lāʻau lapaʻau ʻaʻole lawa).

ʻO nā keiki ma lalo o ka 18 mau makahiki o ka maikaʻi (a ʻoi a me ka palekana o ka hoʻohana) ʻaʻole i hoʻokumu ʻia.

ʻO kahi contraindication hou i ka hoʻohana ʻana iā Neurolipon i ke ʻano o nā kapsul he huakaʻi analary galactose intolerance, hemahema o ka lactase a malabsorption glucose-galactose hoʻi.

Lapaʻau lāʻau

ʻO ka hana ikaika o Neyrolipon - thioctic acid - ua hoʻopili pololei ʻia i loko o ke kino a hana e like me ka coenzyme i ka decarboxylation oxidative o nā waika α-ketonic. Hoʻokomo ka hana koʻikoʻi e ka acid thioctic i ka ikehu metabolism o nā puna. I ke ʻano o ka lipoamide, hana ka paʻakai i ka cofactor koʻikoʻi o nā paepae o ka multi-enzyme, kahi e hoʻomaʻamaʻa nei i ka decarboxylation o nā waika α-keto o ka honu Krebs.

Neyrolipon a me nā waiwai antitoxic a me nā antiioxidant, ma ka hoʻohui, hiki i ka acid thioctic ke hoʻihoʻi i nā antioxidants e like me, no ka laʻana i ka diabetes mellitus, e hōʻemi ana i ka pale o ka insulin a me ka hoʻolohi ʻana i ka hoʻomohala ʻana o ka neuropathy peripheral.

E kōkua ana ka Thioctic acid e hōʻemi i ka glucose o ka plasma a hōʻiliʻili i ka glycogen i loko o ka ate. Hoʻopilikia ia i ka metabolism cholesterol, komo i ka hoʻoponopono o ka metabolism o nā momona a me nā mea e hoʻoneʻe ana i ka momona, hoʻomaikaʻi i ka hana ate ma muli o ka hepatoprotective, antioxidant a me ka detoxification efficacy.

Lapaʻau lāʻau

ʻO nā hiʻohiʻona Pharmacokinetic ma muli o ke ʻano o ka noi:

• ka waha waha: ka hoʻopili ʻana ma ka gastrointestinal tract (gastrointestinal tract) wikiwiki a holo a pau loa, aʻo ka hana o ka Neurolipon me ka meaʻai, hoʻemi ʻia ka absorption. ʻO Bioavailability mai 30 a 60%, ua hoʻohālikelike ka mea ma mua o ke komo ʻana i ka ʻōnaehana ʻōnaehana i ka wā e hele ana i ka paia o ka pā o ka gastrointestinal a me ka ate (first-pass effect). ʻO ka manawa e hiki ai i ka wikiwiki kiʻekiʻe (T_max) e like me 4 μg / ml ma kahi o 30 mau minuke. ʻO ka metabolabolism i loko o ka pehu e hele ana e ka mea o ka oxidation o nā kaulahao ʻaoʻao a me ka hui pū kekahi. Ua hoʻōla ʻia ka lāʻau Thioctic i loko o ka urine ma o nā keiki: ma ke ʻano o nā metabolites - 80-90%, i loli ʻole - ka hapa liʻiliʻi. T_1/2 (hapalua-ola) 25 mau minuke.
• kahu makua: bioavailability o

30%, hōʻiliʻili ka metabolism i loko o ke kōpaʻa e ka oxidation o nā kaulahao ʻaoʻao a me ka conjugation. T_1/2 - 20-50 mau minuke, ʻo ke koina o ka holoi

694 ml / min, ʻo ka nui o ka hoʻohele he 12,7 lita. Ma hope o ka manawa pākahi o ka waikawa thioctic intravenously, ʻo ka hoʻopiʻi ʻana ma nā keiki ma ka 3-6 hola mua i hiki aku i ka 93-100% ma ke ʻano o kahi ʻano i loli ʻole a i ʻole derivatives.

Nā ʻōkuhi no ka hoʻohana ʻana iā Neyrolipon: ke ʻano a me ka helu ʻana

Lawe ʻia ka huaola neoneo capsule ma kahi ʻōpū ʻole (hapa hapalua hola ma mua o kahi manawa ʻai), me ka ʻaʻewa ʻole a me ka inu me ka wai liʻiliʻi a i ʻole kekahi wai kūlohelohe.

Ke kuhikuhi ʻia nei: 300-600 mg hoʻokahi i ka lā. No ka mālamaʻana i ka polyneuropathy maʻi diabetes i ka hoʻomaka, ka makemake makua ʻana o ka wai thioctic acid.

Hoʻoholo ke kauka i ka lōʻihi o ke papa o ka lapaʻau.

Hoʻopili i nā hopena no ka hoʻopuʻe

Hoʻololi ʻia ka hopena o ka hoʻokele ʻana mai ka Neyrolipon ma ke ʻano o ka infusion intravenous infusion (≤ 50 mg thioctic acid i hoʻokahi minuke).

Manaʻo ʻia: 600 mg hoʻokahi manawa i ka lā, i nā pilikia koʻikoʻi, a hiki i ka 1200 mg ʻae ʻia.

No ka hoʻomākaukau ʻana i ka hoʻonā infusion, hoʻohana ʻia kahi hopena 0.9% NaCl i ka nui o 50-250 ml no 600 mg o ka thioctic acid.

ʻO ka lōʻihi o ka papa o ka lapaʻau he mau lā 2 hebedoma, ma hope o lākou e hoʻololi ai i ka mālama mālama ʻana me ka acid thioctic ma ke ʻano o ka hoʻomākaukau waha (dosis o 300-600 mg i kēlā me kēia lā) no nā mahina 1-3.

I mea e hoʻohui ai i ka hopena o Neyrolipona, ua makemake ʻia e alakaʻi i nā papa i hoʻopaʻi ʻia me 2 mau manawa i ka makahiki.

Ke keu

ʻO nā ʻōmaʻomaʻo o ka nui o ka waika thioctic i ka wā e lawe ʻia ai ke poʻo hiki ke poʻo, hōʻino, ka luaʻi, hoʻomākeʻela nui, nā hana hōʻeha nui i ka hoʻohuʻuku i ka acid-base me ka lactic acidosis, hypoglycemic coma, nā ala coagulation koko nui a hiki i ka make.

No ka mālama ʻana i ke ʻano, pono ʻoe e hoʻokaʻawale i ka lawe ʻana i ka lāʻau, holoi a i ka ʻōpū, a laila lawe i ka ulana ʻia, a hoʻokō ʻia ka mālama mālama.

ʻAʻole maopopo ka ʻike ʻana i nā ʻano kumu nui o ka waihuna thioctic me ke ʻano makua.

Inā kuhi ʻoe i kahi overdose a i ʻole ka hopena o nā hopena maikaʻi loa, pono ʻoe e hoʻopilikia i ka infusion, a laila, me ka ʻole o ka lawe ʻana i ka nūpepa wīwī, hoʻoiho mālie ia i ka hopena 0.9% isotonic NaCl ma o ka ʻōnaehana. ʻAʻole loaʻa ka lāʻau lapaʻau i kekahi antidote kiko'ī;

Nā ʻōlelo kikoʻī

ʻO ka hoʻonāʻana o nā infusion e loaʻa i ka waikawa thioctic e pono e pale mai ka māmā ma ka uhi ʻia ʻana o nā mea lawe me nā pale pale māmā.

I ka mālamaʻana i nā maʻi me ka maʻi maʻi, nānā pinepine ʻia nā kaohi glucose o ke koko, i kekahi mau mea, inā pono, e hoʻoponopono ʻia ke ʻano o nā māka hypoglycemic i mea e pale ai i ka hoʻomohala ʻana o ka hypoglycemia.

I ka wā o ka mālama ʻana me Neurolipone, pono ka mea e pale i ka inu ʻana i ka mea inu wai ʻona, ʻoiai ke kāohi nei ka ethanol i kāna hana therapeutic.

Hoʻohui nūhou

• glucocorticosteroids: hoʻonui ka thioctic acid i ko lākou anti-inflammatory eff,
• cisplatin: ua hoʻemi ʻia ka emi ʻana o kona hopena therapeutic,
• nā lāʻau lapaʻau e pili ana i nā metala (hao, magnesium, calcium hoʻomākaukau): thioctic acid ikomi i nā metala, no laila, pono e pale ʻia kā lākou lawelawe me ka manawa, pono e mālama i kahi wāwē ma waena o nā liʻiliʻi he 2 mau hola,
• insulin a waha waha paha hypoglycemic: hiki i ka acioctic acid ke hoʻokaʻawale i ko lākou hopena,
• ethanol a me nā metabolites: pale i ka hana a ka thioctic acid.

ʻO ka hopena infusion o Neyrolipon i hoʻohālikelike ʻole i ka punawai me ka puna, no laila ʻaʻole kūpono i nā hoʻonā o ka Ringer, glucose, a me ka fructose. ʻAʻohe nō hoʻi ia i nā hoʻoponopono o nā mea hoʻohui e hōʻike pū ana me SH-pūʻulu a i ʻole i hoʻokau ʻia i nā alahaka a me nā hoʻomākaukau e loaʻa ana ka ethanol.

Nā ʻike e pili ana i ka neuroleepone

Kūlike nā loiloi e pili ana i ka neuroleepone. No kekahi mau mea maʻi, ʻaʻole kūpono iki ka lāʻau lapaʻau, ka mea i kapa ʻia he hopena maikaʻi ʻole ia e hōʻoluʻolu iki i nā hōʻailona o ka maʻi a hana i kahi hopena ʻino loa.

Ma kahi o nā loiloi hou kekahi, ua ʻike ʻia ka neurolypone e like me ka lāʻau e koho ai ma muli o ka loaʻa ʻole o nā hopena ʻino a me ka hana kiʻekiʻe.

ʻO ke kumu kūʻai o Neyrolipon i loko o nā lāʻau lapaʻau

Kuhi kumukūʻai no NeroLipone:

• hoʻokūkū i ka hoʻomākaukau o kahi hopena no ka infusion (5 ampoules i kahi ʻeke pepa): i nā ampoules o 10 ml - 170 rubles, i nā ampoules o 20 ml - 360 rubles,
• mau kaleka (10 pcs. in blisters, 3 blisters in a pack of cardboard) - 250 rubles.

Ka hoʻonaʻauao: ʻO ke Kulanui Kauka Kahikole ma Moscow i kapa ʻia ma hope o I.M. Sechenov, hoʻolālā "General Medicine".

Hōʻike nui ʻia ka ʻike e pili ana i ka lāʻau lapaʻau, i hoʻolako ʻia no ka hana ʻike a ʻaʻole hoʻololi i nā ʻōlelo aʻoaʻo. Hoʻopilikia ka lāʻau-pono iā ia ke olakino!

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

Hoʻonohonoho ʻia ka hopena no ka infusion i ka poʻe maʻi ma kahi o 600 mg o ka lā. Hoʻohana iki ia - ʻaʻole ia e ʻoi aku ma mua o 50 mg o ka lāʻau thioctic (1.7 ml o ka hopena no ka infusion) i hoʻokahi minuke.

ʻO ka lāʻau lapaʻau e pono e lawelawe ʻia e ka infusion me ka hopena o ka sodium chloride 0.9% 1 ka manawa i kēlā me kēia lā (600 mg o ka lāʻau i hui pū ʻia me 50-250 ml o kahi hopena o ka sodium klorida 0.9%). I nā pilikia koʻikoʻi, hiki ke hoʻokele a hiki i 1200 mg. Pono e pale ʻia nā hoʻonāpili infusion mai ka mālamalama e uhi iā lākou me nā pale pale māmā.

ʻO ka papa ala o ka mālama ʻana mai 2 a 4 mau pule. Ma hope o kēlā, huli lākou i ka mālama mālama ʻia me Neyrolipon no ka hoʻokele waha (capsules) i kahi maʻi o 300-600 mg i hoʻokahi lā no 1-3 mau mahina. Lawe ʻia nā Kūpula me ka hilahila ʻole, holoi ʻia me ka wai liʻiliʻi, 30 mau minuke ma mua o kahi pāʻina (ma kahi ʻōpū ʻole). Ke hoʻohui i ka hopena o ka hana lapaʻau, ʻoi aku kahi papa o ka lapaʻau ʻia i 2 manawa i ka makahiki.

Hoʻoholo ʻia ka lōʻihi e ke kauka.

ʻAʻole paʻa i ka pono a me ka palekana o ka lāʻau i nā keiki.

Ka hana lāʻau lapaʻau

Thioctic acid, kahi mea ia o Neuro Lipon, ke synthesized i loko o ke kino a hana e like me ka coenzyme i ka decidboxylation o ka oxidative decarboxylation o nā aʻa alpha-keto, a ke hana i ka mea nui i ka pūnaehana metabolism o ka puna. Ma ka ʻano amide (lipoamide), he cofactor koʻikoʻi o nā komplikine multi-enzyme e hoʻopōleʻa ai i ka decarboxylation o nā krebs alpha-keto. He Thitooctic acid ua loaʻa nā hopena antitoxic a me nā antioxidant, hiki ke hoʻihoʻi hou i nā antioxidants ʻē aʻe, e like me ka maʻi maʻi. I nā maʻi me ka maʻi diabetes, hoʻemi ʻia ka wai thioctic i ka pale ʻana i ka insulin a pale i ka hoʻomohala ʻana o ka neuropathy peripheral.

Kōkua ia i ka hoʻemi ʻana i ka kao o ka glucose i loko o ke koko koko a me ka hōʻiliʻili ʻana o ka glycogen i loko o ka ate. Hoʻopilikia ka wai Thioctic i ka metabolism o ka cholesterol, e komo i ka hoʻoponopono o ka lipid me ka metabolism, ka hoʻomaʻamaʻa ʻana i ka hana ate (ma muli o ka hepatoprotective, antioxidant, detoxification effects).

Hoʻohui

Hoʻonui i ka hopena anti-inflammatory o nā lāʻau glucocorticosteroid.

Me ka mālama like ʻana o ka wai thioctic a me cisplatin, kahi i hoʻemi ʻia ai ka hopena o ka cisplatin.

Hoʻopili i ka waikawa Thioctic no nā metala, no laila, ʻaʻole pono e kuhikuhi pū ʻia i nā lāʻau lapaʻau e pili ana i nā metala (no ka laʻana, hao, magnesium, kalima) - ʻo ke kikowaena ma waena o nā dosis he liʻiliʻi ma kahi o 2 mau hola.

Me ka hana like o ka wa thioctic acid a me ka insulin a i ka lāʻau hypoglycemic oral, e hoʻonui paha i kā lākou hopena.

ʻAno nā alkoholika a me nā metabolites e hoʻonāwaliwali i ka hopena o ka neuroleipone.