Humalog - nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana, nā mea hoʻohālike, nā loiloi a me nā puka hoʻokuʻu (QuickPen pen syringe me kahi hopena a i ʻole ke hoʻoneʻe ʻia mai ka mix 25 a me 50 insulin) o ka lāʻau lapaʻau no ka mālama ʻana o ka ʻano type type 1 a me ka type 2 ma ka pākeke, nā keiki a i ka wā hāpai
I kēiaʻatikala, hiki iā ʻoe ke heluhelu i nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau Humawai. ^ E Ha yM. Hāʻawi i ka hoihoi mai ka poʻe kipa i ka pūnaewele - nā mea kūʻai o kēia lāʻau lapaʻau, me nā manaʻo o nā loea lapaʻau e pili ana i ka hoʻohana ʻana iā Humalog i kā lākou hana. ʻO kahi noi nui, ʻo ia ke hoʻoikaika ikaika i kāu mau loiloi e pili ana i ka lāʻau lapaʻau: kōkua ka lāʻau lapaʻau a ʻaʻole hoʻi i kōkua i ka hoʻopiʻi ʻana i ka maʻi, nā mea hoʻopiʻi a me nā hopena ʻaoʻao, ua ʻike ʻia, ʻaʻole paha e hoʻolaha ʻia e ka mea hana ma ka palapala. Nā hōʻike o ka Humalog i ke alo o nā mea hoʻohālike e pili ana. Hoʻohana no ka mālama ʻana i ka ʻano type mika a me ke ʻano type 2 type (insulin-depend and non-insulin-depend diabetes) i nā pākeke, nā keiki, ʻoiai ʻo ka wā hapai a me ka lactation. ʻO ka hiʻohiʻona o ka lāʻau lapaʻau.
Humawai - ke aniani o ke kūlohelohe o ke kanaka, ʻokoʻa ʻole mai ia e ke ka hoʻohuli ʻana o ka proline a me ka lysine amino acid residues i nā kūlana 28 a 29 o ka kaulahao B B. Hoʻohālikelike me ka hoʻomākaukau ʻana o nā hana hana pōkole hana pōkole, ʻike ʻia ka insulin lyspro e ka wikiwiki a me ka hopena o ka hopena, ʻo ia ka mea i hoʻonui ʻia aʻe ai ka nui o ka subcutaneous depot ma muli o ka mālama ʻana i ka molina monomeric o ka molika insulin lyspro i loko o ka hopena. ʻO ka hoʻomaka ʻana o nā hana he 15 mau minuke ma hope o ka lawelawe ʻākana, ʻo ka hopena ma waena o 0,5 mau hola a me 2,5 mau hola, ʻo ka lōʻihi o ka hana he 3-4 mau hola.
ʻO ka Humalog Mix kahi DNA - recombinant analogue o ka hana kanaka a me kahi hui mākaukau paʻa e ka ʻoli a me ka hopena o ka insulin lyspro (kahi hana wikiwiki o ka inika no ke kanaka) a me ka hoʻokuʻuʻana i ka insulin lyspro protamine (medium-duration human insulin analog).
ʻO ka hana nui o ka lyspro insulin ʻo ia ka hoʻoponopono ʻana o nā hana kū ka pehu. Eia kekahi, he ia nā hopena anabolic a me nā anti-catabolic i nā kiko kino o nā kino. I loko o ka kiko o ka iwi, ka nui o ka loaʻa o nā mea o ka glycogen, ka momona o ka momona, ka glycerol, ka nui o ka hoʻouluʻana o ka protein a me ka hoʻonui ʻana i ka ʻai o nā waikawa amino, akā i ka manawa like, he nui ka manawa o ka glycogenolysis, gluconeogenesis, ketogenesis, lipolysis, protein catabolism a me ka hoʻokuʻu ʻana o nā waikawa amino.
Hōʻike
ʻO Lyspro insulin + nā mea hoʻonani.
Lapaʻau lāʻau
ʻO ka piha holoʻokoʻa o ka pākuʻi ʻana a me ka hoʻomaka ʻana o ka hopena o ka insulin e hilinaʻi ana ma ka wahi o ka maʻi (ka ʻōpū, ka ʻūhā, nā ʻūhā), ka make (ka nui o ka inika i hāpaʻi ʻia), a me ka ʻike ʻana o ka insulin i ka hoʻomākaukau. E kahele ʻia ʻokoʻa ma nā kiko. ʻAʻole ia e hele i ka pale o ka placental a i ka waiū umauma. Ua luku ʻia ia e ka insulinase ma ka nui a me nā kau. Hoʻokuʻu ʻia ia e nā keiki - 30-80%.
Nā Hōʻike
- maʻi 'āpau 1 mellitus (pili i ka insulin), a me ke komo pū me ka hoʻomanawanui ʻole i nā hoʻomākaukau insulin ʻē aʻe, me ka hyperglycemia postprandial ʻaʻole hiki ke hoʻoponopono ʻia e nā ʻano ʻē aʻe o ka insulin, ka kūʻē kūpaʻa insulin subcutaneous (wikiwiki i ka hōʻino ʻana i ka insulin).
- type type diabetes 2 mellitus (non-insulin-depend): me ke kū'ē ʻana i nā waha o hypoglycemic waha, a me ka hoʻopiʻi ʻana i nā ʻaina ʻē aʻe o ka hoʻomākaukau ʻana i ka insulin, ka hyperglycemia postprandial postprandial.
E hoʻokuʻu i nā palapala
ʻO kahi hopena no ka hoʻolālā intravenous a subcutaneous o 100 IU i kahi pahu pahu 3 ml i hoʻokomo pūʻia i loko o ka penina QuickPen a peni pū hoʻi.
Hoʻopili ʻia no ka hoʻokele subcutaneous o 100 IU i kahi pahu kū pahu 3 ml i hoʻohui ʻia i ka penina QuickPen a pen penikala paha (Humalog Mix 25 a 50).
ʻO nā pepa dosage ʻē aʻe, he mau papa a he kapa hoʻi, ʻaʻole i noho.
Nā ʻōkuhi no ka hoʻohana a me ke ʻano o ka hoʻohana
Hoʻonohonoho ʻia ka ʻona hoʻokahi. ʻO ka insulin Lyspro e mālama ʻia i ka subcutaneously, intramuscularly a i ʻole intravenously 5-15 mau minuke ma mua o kahi pāʻina. I hoʻokahi kauka no 40 mau ʻāpana, ʻae ʻia ka nui o nā mea kūʻokoʻa loa. Me ka monotherapy, e mālama ʻia ana ka ʻohana Lyspro i 4-6 mau lā i ka lā, i hui pū me ka hoʻomākaukau ʻana i nā insulin like lōʻihi - 3 mau manawa i ka lā.
ʻO ka lāʻau lapaʻau e pono e hoʻokele i ka subcutaneously.
Hoʻopuka ka intravenous hoʻokō i ka lāʻau Humalog Mix.
Pono ka wela o ka lāʻau lapaʻau i ka mahana o ka lumi.
Pono e paʻi ʻia ka Subcutaneous i loko o ka poʻohiwi, ka ʻūhā, ka ʻūhā a me ka ʻōpū paha. Pono e hoʻololi ʻia nā wahi i ʻōlelo ʻia a hoʻohana ʻia kahi wahi like ʻole ma mua o 1 mau manawa i hoʻokahi mahina. I ka manawa o / i ka hoʻomaka ʻana o ka lāʻau Humalog, pono e mālama ʻia e pale aku i ka lāʻau lapaʻau i loko o kahi moku koko. Ma hope o ka loaʻa ʻana, ʻaʻole pono e ʻā ʻia ka pūnaewele inikua.
Ke kau nei i kahi kaila i loko o kahi inikini inikini insulin a hoʻopili i kahi pono ma mua o ka lawelawe ʻana i ka insulin, pono ke kiaʻi pono ʻia nā ʻōlelo a ka mea hana o ka ʻenehana inake insulin.
Nā rula no ka hoʻokomo ʻana i ka lāʻau Humalog Mix
Hoʻomākaukau no ka hoʻomaka
Ma mua o ka hoʻohana ʻana, pono e ʻaloʻalo ʻia ka pahu kāwili o Humalog mix ma waena o nā pālima i kahi ʻumi a lūlū ʻia, huli ʻana he 180 ° he ʻumi mau manawa e hoʻoulu hou ai i ka inanini a hiki i ka ʻano me ka waiū. E lulu ʻoluʻolu, me hiki kēia i ke alakaʻi i ka busa, hiki ke hōʻole me ka wī pololei. I mea e hoʻomaʻamaʻa ai ke hoʻāwili ʻana, loaʻa i ka pahu kāwili liʻiliʻi i kahi beahi aniani. ʻAʻole pono e hoʻohana ʻia ka lāʻau lapaʻau inā loaʻa nā flakes ma hope o ke kāwili ʻana.
Pehea e hoʻokele ai i ka lāʻau lapaʻau
- Holoi lima.
- E koho i kahi no ka maʻi.
- Mālama i ka ʻili me kahi antiseptic ma ke kahua o ka inikua (me ka ʻōlelo iho pono ʻia, e like me nā ʻōlelo a ke kauka).
- Hoʻopau i ka pāpale pale palekana mai ka pono.
- E hoʻoponopono i ka ʻili ma ka huki ʻana a hoʻopaʻa ʻia paha i kahi pā nui.
- Hoʻokomo i ka lāʻau pono a me ka hana ʻana i ka injection e like me nā ʻōlelo no ka hoʻohana ʻana i ka peni syringe.
- Hoʻokuʻu i ka nūpepa a me ka hoʻomoʻe ma ka ʻaoʻao o ka injection no kekahi mau sekona. Mai hōʻaleʻa i ka pūnaewele wili.
- Ke hoʻohana nei i ka pāpale pale pale o waho o ka pono, e kāpae i ka pono a luku aku iā ia.
- E kau i ka pāpale ma ka peni syringe.
Loaʻa ka hopena
- ka hypoglycemia (hypoglycemia koʻikoʻi hiki ke alakaʻi i ka ʻike ʻole a, i nā hihia ʻē aʻe, i ka make),
- ʻulaʻula, kūleʻa, a ʻehaʻalani paha ma ka pūnaewele i ʻōlelo ʻia (maʻa mau i loko o kekahi mau lā a i ʻole hebedoma paha, i kekahi mau hanana a hiki ke hōʻāhewa ʻia kēia mau kumu e nā kumu i pili ʻole i ka insulin, no ka laʻana, ka huhū ʻili o ka ʻili e kahi antiseptic a i ʻole ka mea kūpono ʻole).
- laulā maʻamau
- paʻakikī ka hanu
- ʻaʻano pōkole
- emi i ke koko,
- tachycardia
- hoʻonui hoʻonui ʻia
- ka hoʻomohala ʻana o ka lipodystrophy ma ka pūnaewele injection.
Nā Hoʻohui
- huahuʻi,
- hypersensitivity i nā ʻāpana o ka lāʻau.
ʻŌpū a me ka lactation
I kēia lā, ʻaʻohe mau hopena i makemake ʻia o ka insulin Lyspro i ka wā hāpai a i ʻole ke ʻano o ka pūpū a me ka pēpē hou.
ʻO ka pahuhopu o ka insulin therapy i ka wā hapai ke mālama i ka lawa glucose kūpono. Ka pono o ka insulin e hoʻemi i ka trimester mua a hoʻonui i ka trimesters lua a me ke kolu o ka hapai. I ka wā a ma hope o ka hānau ʻana, hāʻule paha nā koi o ka insulin.
Pono nā wahine o nā keiki hāpai keiki me ka maʻi maʻi maʻi e hoʻomaopopo i ke kauka e pili ana i ka wā hoʻomaka a i ʻole kahi hoʻolālā i hoʻolālā ʻia.
I nā maʻi me ka diabetes mellitus i ka wā o ka mālamaʻana, e koi ʻia kahi hoʻoponopono o ka insulin a / a i ʻole meaʻaiʻai.
Nā ʻōlelo kikoʻī
ʻO ke ala o ka hoʻokele i manaʻo ʻia no nā ʻano laima o ka inika lyspro e pono e kiaʻi pono ʻia. Ke hoʻokaʻawale nei i nā maʻi i ka hoʻomākaukau ʻana i ka hoʻomākaukau ʻana i ka inehini me ka hoʻomaka ʻana o nā holoholona mai ka lālani insulin, e koi ʻia ka hoʻoponopono ʻana. ʻO ka hoʻoneʻe ʻana o nā mea maʻi e loaʻa ana i ka inika i kahi lā i kēlā me kēia lā ma mua o 100 PIECES mai kekahi ʻano o ka inehina i kekahi ʻē aʻe ua makemake ʻia e lawe ʻia i loko o ka haukapila.
Hiki ke hoʻonui i ka insulin i ka manawa o ka maʻi ʻeha, me ka uha ʻana i ke ʻano, me ka hoʻonui ʻana i ka nui o nā huapalapala i ka meaʻai, i ka wā o ka komo o ka lāʻau lapaʻau me ka hana hyperglycemic (hormone thyroid, glucocorticoids, oral contraceptives, thiazide diuretics).
Pono ka emi ʻana o ka insulin me ka renal a me / a me ka hāʻule ʻole o ka palupalu, me ka hoʻohaʻahaʻa ʻana i ka nui o nā huamina i ka meaʻai, me ka nui o ka hoʻoikaika kino, i ka manawa o ka hoʻokomo o nā lāʻau lapaʻau me ka hana hypoglycemic (MAO inhibitors, beta-blockers non-selective, sulfonamides).
Ke hoʻoponopono nei i ka hypoglycemia ma kahi kūlana koʻikoʻi e hiki ke hana ʻia me ka hoʻohana ʻana i / m a / i ʻole a i ʻole a i ʻole a i ʻole ka mana o ke ʻano o ka glucagon a i ʻole ka lawelawe ʻana o ka glucose.
Hoʻohui nūhou
Hoʻonui ʻia ka hopena hypoglycemic Lyspro insulin e ka MAO inhibitors, non-selective beta-blockers, sulfonamides, acarbose, ethanol (alkohol) a me nā mea kanu e pili ana ka ethanol.
ʻO ka hopena hypoglycemic o Lyspro insulin e hōʻemi e ka glucocorticosteroids (GCS), nā thyroid hormones, oral contraceptives, thiazide diuretics, diazoxide, tricyclic antidepressants.
Hiki i nā Beta-blockers, clonidine, reserpine ke uhi i nā hōʻike o nā hōʻailona o ka hypoglycemia.
Nā kuʻina o ka lāʻau Humalog
Hoʻololi nā kumu hoʻohālike o ka waiwai ikaika:
- ʻO ka inini Lyspro
- Humalog Mix 25,
- Humalog Mix 50.
Nā kikowaena e ka hui pharmacological (insulins):
- Acfapid HM Penfill,
- Actrapid MS,
- B-Insulin S.Ts. ʻO Berlin Chemie,
- Berlinsulin H 30/70 U-40,
- Berlinsulin H 30/70 pen,
- Berlinsulin N Basal U-40,
- Berlinsulin N Basal Pen,
- Berlinsulin N Normal U-40,
- Berlinsulin N Normal Pen,
- Nā wai hoʻohālikelike C,
- ʻO ka Ipu ʻo Isofan Insulin,
- Iletin
- Insulin Tape SPP,
- Insulin c
- Hoʻomaʻemaʻi loa ʻia me ka ʻoli puaʻa MK
- Insuman Comb,
- Intral SPP,
- ʻ Cupʻī
- ʻO nā Kūkākūkā C
- Mikstard 30 NM Penfill,
- Monosuinsulin MK,
- Monotard
- Penulin
- Protafan HM Penfill,
- Protafan MS,
- Rinsulin
- Ultratard NM,
- Homolong 40,
- Homorap 40,
- Humulin.