Hoʻokomo Lizoril - (Lisoril) no ka hoʻohana ʻana

ʻO ka wehewehe e pili ana i 28.12.2014

• Palapala Latin: Lisinopril
• ʻĀkau ATX: C09AA03
• Mea waiwai: Lisinopril (Lisinopril)
• Mea Hana: Avant (Ukraine), Skopinsky Pharmaceutical Plant, ALSI Pharma, ZiO-Zdorovye, Severnaya Zvezda, Ozon LLC, Biochemist, Obolenskoye - nā mea kūʻai lāʻau lapaʻau, Canonfarm Production CJSC, VERTEX (Russia)

ʻO ka mahele nui o ka lāʻau lapaʻau ka lisinopril dihydrate. ^ E Ha yM. Akā, ma muli o ka mea hana o ka lāʻau, he ʻokoʻa ka hoʻolālā o nā mea hou.

Hoʻopili ke kamupene Ukraine ʻO Avant iā Lisinopril me nā mea kōkua like ʻano keʻa mahina,kalekaʻiuna kalapuna kaleha,hao wai, mannitol,paʻahau magnesium.

A hana ka mea hoʻohana o Rūka ALSI Pharma i kahi huahana me nā mea hou aʻe: ke kumu pregelatinized,colloidal kaomi silika,ka leʻaleʻa talcum,liʻawaʻawa lactose, cellulose microcrystalline,paʻahau magnesium.

Eia kekahi, ʻo ia mau ʻano o ka hoʻokuʻu i ka lāʻau, ʻike ʻia ʻo Lisinopril-Ratiopharm, Lisinopril-Astrafarm, Lisinopril Teva, Lisinopril Stada. Ua loaʻa iā lākou nā māhele hou aʻe:

• Lisinopril-Kauhane ʻano keʻa mahina,colloidal kaomi silika,mannitol,kalekaʻiuna kalapuna kaleha, paʻahau magnesium,
• Lisinopril-Kekauoha - mannitol,kalekaʻiuna kalapuna kaleha, paʻahau magnesium, ke kumu pregelatinized, kahi sodium a ʻaihoe (Nā papa papa 20 mg ka waihona pū me ka PB-24824, a me ka lāʻau lapaʻau ma nā papa o 10 mg i loaʻa ka pupu PB-24823).

ʻO Lisinopril Stada kahi mea hoʻoikaika i ka lāʻau lisinopril hydrate. ^ E Ha yM. A i ka hoʻohui, i kēia mau mea e hoʻonui ai: ke kumu pregelatinized,wili Silic oxide colloidal anhydrous, mannitol,paʻahau magnesium,ʻano keʻa mahina, kaleka ka calcium phosphate disubstituted dihydrate.

Pharmacodynamics a me ka pharmacokinetics

Lisinopril papa poloka ACEhoʻonui i nā ʻike GHG lawaiʻa hopena a hoʻomāliʻi i ka hoʻololi angiotensin I i loko angiotensin II. ^ E Ha yM. Hoʻemi lākou i ka hoʻololi ʻana. arginine-vasopressina huakai-1, hōʻemi i ka myocardial afterload, ka nui o ka pale ʻana i kēlā me ko peripheral vascular, ka pāpale pulmonary pressure a me ke ʻano o ke koko systemic. I nā maʻi me puʻuwai paʻakikī hoonui i ka ahonui myocardial i ka hana a huapalapala output. ^ E Ha yM. Māhuahua i ka hana hoʻonui renin Pūnaewele.

Hoʻopili ka lāʻau lapaʻau i nā kiko renin-angiotensin pale i ka naʻau puʻuwai, pale i ke ʻano o ke myocardial hypertrophy a dilatations haʻalele i ka ventricle a kōkua paha i ko lākou nalowale ʻana.

Hōʻike ka hopena o ka lāʻau ma hope o kahi he 60 mau minuke, hoʻonui i nā hola 6-7 a kū hoʻokahi lā. Kūpono loa antihypertensivehōʻike ʻia ka hopena i loko o kekahi papa o nā pule.

Hoʻopili ʻia ka mea momona e ka 25%. ʻAʻole pili ke ʻano i ka manawa ʻaina. He haʻahaʻa nā kamaʻilio ʻana me nā protein plasma. ʻAʻole kahi biotransformed a me ka hoʻopā ʻia e nā keiki i loli ʻole. ʻO ka hoʻopau hapa hapalua-ola he 12 mau hola.

Nā Hoʻohui

ʻAʻole pono ka lā o ka lāʻau lapaʻau me ka haaheo i kāna mau mea, lactation a hapai.

ʻAʻole hiki i ke kau ke kuhikuhi i kēia lāʻau no ka:

• hyperkalemia,
• hopena anaphylactoid,
• nā huinaʻi,
• hemahema cerebrovascular,
• huakini a me ka hana lima,
• palipale stenosis hāmeʻa like ʻole,
• transplanted kidney
• kohola,
• elemakule
• ʻO ka edema ʻo Quincke i loko mōʻaukala,
• ʻeha ko ka naʻau ʻōiwi,
• hypotension,
• nā hoʻololi i kaʻe e pale ai i ka kahe ʻana koko mai ka naʻau
• hyponatremia, aia pū me ka ʻai me ke kō ʻole kahi hapa o ka sodium,
• ka stenosis o hoʻokahi artery kidney,
• pālahalaha maʻi,
• nā makahiki o nā keiki.

Nā hopena hopena

Hiki i nā hopena ʻaoʻao ke ala, kū mai lākou i nā ʻōnaehana like ʻole a me nā hui:

Eia kekahi, hiki ke hōʻike ʻia i kēia mau ʻano: hiki ke hoʻomohū ʻana i nā maʻi kuʻuna, lawe kaumaha, kaohuu, maʻi mellitus maʻiʻie hāpai ana antinuclear anti titer a me ka ʻike urea, koholahoʻonui hoʻonui kiʻekiʻe mea hana, hyperkalemia, pālahalaha maʻi, fiva, allergy, huehue, hyponatremia.

Inā ʻike ʻia nā hopena ʻaoʻao, pono e nīnau koke i kahi loea.

Ke keu

I ke kūlana o kahi overdose, ma ke ʻano he lula hypotension kaulike. ^ E Ha yM. Ma ke ʻano he mālama ʻana, e mālama ʻia ka paʻakai physiological. Hoʻomaka ʻia ke ʻano maʻi Symptomatic.

Eia kekahi, hiki i ka pīhoihoi, hoʻolahaa, huehae huehal i pau, brieociaia, Ulu, hemahema electrolytes i loko o ke koko tachycardiapuʻuwai puʻuwai āhāhuʻehopohopo aloha.

Pono e hōʻemi ʻia ka lāʻau lapaʻau. Inā ʻike ka mea maʻi, holoi lākou i ka ʻōpū, waiho i ka mea maʻi i kona kua me ke kua haʻahaʻa haʻahaʻa, ke kū nei i nā wāwae a me ke poʻo. Eia kekahi, hāʻawi lākou hoʻohui.

Ke lawe nei i ka lāʻau lapaʻau i nā kiʻekiʻe koʻikoʻi, pono e hoʻokipa koke ʻia ka mea maʻi. Ma kahi hale haukapila, ke mālama ʻia nei ka mālama ʻia e mālama ana i ke ʻano maʻamau ʻaila poni, nā neʻe koko, ka hanu, hoʻihoʻi i ka nui o ke kahe koko a me ka hana maʻamau. Hoʻohana maikaʻi hemodialysis. ^ E Ha yM. Hōʻike e nānā i nā hōʻailona o nā hana nui, a me ka pae mea hana a electrolytesi loko o kahi serum.

Hoʻohui

Ke lawe nei i ka lāʻau lapaʻau me antihypertensivehiki ke hoʻonāukiuki i ka lāʻau lapaʻau hoʻohui hoʻohui antihypertensive hopena.

Diuretics pākakai-sparing, ka mea i koho no ka paʻakai me ka pāhare, ʻoi pū kekahi me nā potala e hoʻonui i ka hiki ke hoʻomohala hyperkalemia.

E hui pū me nā palaka ACE a Nā NSAIDhoʻonui i ka loli i ka hana renal impaired. I nā hihia maʻamau, hiki nō hoʻi hyperkalemia.

A nā noi e hui pū me kūwaha hoʻi a diuretics thiazide piha me ka hoʻonui antihypertensive hana. Hoʻonui nui kēia i ka pilikia o ka hana renal impaired.

Nā Indomethacin ai kālā paha me estrogen i ka hui me lisinopril alakaʻi i kahi i emi antihypertensive hana a nā hopena hope. He hoʻokipa hoʻokipa Insulin ahypoglycemic hiki i nā lāʻau lapaʻau ke kumu hypoglycemia.

ʻO ka hui pū me ka clozapine alakaʻi i kahi hoʻonui i kona manaʻo i ka plasma. ʻOiai e lawe ana litium karbonat hoʻonui ka kiʻekiʻe o ka serum koko. E hele pū paha kēia me nā hōʻailona o ka hoʻohuihui lithium.

Hoʻonui ka lāʻau i ka hopena o ka ethanol. Hoʻohālikelike ʻia nā hōʻailona o ka hoʻomohala. I ka manawa like, hiki ke hoʻonui pū antihypertensive ka hopena o ka lisinopril, no laila he mea pono ke pale aku i ka waiʻona i ka wā o ka lāʻau me kēia lāʻau a ʻaʻole ʻole e lawe iā ia i loko o 24 mau hola ma hope o ka inu ʻawa.

ʻO ka hoʻohana ʻana i kēia lāʻau lapaʻau i ka hui pū ʻana me nā kālā no anesthesianakawai analgesics, antiidepressants, hōʻano ʻoliā me hypotensive hana, ʻo ia hoʻi ʻo nā pale hiamoe e alakaʻi i ka nui antihypertensive hopena.

Pūnaewele hoʻonui i ka hopena haehae maʻi. ^ E Ha yM. Pono e hui pū ʻia kēia hoʻohui me ka akahele a nānā pono i ke ʻano o ka mea maʻi.

ʻO nā Sympathomimetics nāwaliwali loa antihypertensive hopena o ka lāʻau lapaʻau. ʻO kahi hui me nā lāʻau lapaʻau e hoʻolako myelosuppressivehoonui ka hana agranulocytosis a me / neutropenia.

Hoʻohana me Allopurinol, immunosuppressants, Procainamide, sittostatics, corticosteroids kumu paha leukopenia.

I dialisishiki i nā lāʻau lapaʻau hopena anaphylactoid i ka hihiakiʻekiʻe ka maʻi polyacrylonitrile kiʻekiʻe.

E hoʻokuʻu i ke ʻano, ka pūpū a me ka hoʻopiʻi Lizoril ®

10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.
14 ʻōpō. - nā ʻili uila (2) - nā ʻeke pepa.

Nā mea kūʻai: kōpuna, mannitol, dicalcium phosphate dihydrate, magnesium stearate, iron dye oxide red.

10 kamepiula - blisters (3) - nā ʻeke pepa.
14 ʻōpō. - nā kāmele (2) - nā kīʻaha o ke kāleka.

Nā mea kūʻai: kōpuna, mannitol, dicalcium phosphate dihydrate, magnesium stearate, iron dye oxide red.

10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.
14 ʻōpō. - nā ʻili uila (2) - nā ʻeke pepa.

Nā mea kūʻai: kōpuna, mannitol, dicalcium phosphate dihydrate, magnesium stearate, iron dye oxide red.

10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.
14 ʻōpō. - nā ʻili uila (2) - nā ʻeke pepa.

Ka hana lāʻau lapaʻau

ACE paleʻai. Mālama i ka hoʻokumu ʻana o ka angiotensin II mai angotensin I. Hoʻēmi ia i ka ʻike o ka angiotensin II a alakaʻi i kahi hoʻohemo pololei i ka hoʻokuʻu ʻana o ka aldosterone. Hoʻemi i ka hōʻemi o ka bradykinin a hoʻonui i ka syntaglandin synthes. Hoʻemi i ka huakaʻi kūloko peripheral, ke koko, ka preload, ka paila pulillary pulmonary, e hoʻonui ai i ka hopena o ka cardiac a me ka hoʻonui ʻana i ka hoʻololi Myocardial i ke kaumaha i nā poʻe maʻi me ka hōʻeha ʻole o ka naʻau. E hoʻonui i nā arela i ka ʻoi aku ka nui ma mua o nā veins. Ua wehewehe ʻia kekahi mau hopena e ka hopena ma ka ʻimi renin-angiotensin. Me ka hoʻohana ʻana i ka lōʻihi, ua emi nā hypertrophy o ka myocardium a me nā paia o nā ʻāpana o ke ʻano o ka mea pale. Hoʻomaikaʻi i ka hāʻawi ʻana i ke koko i ka myocardium ischemic. Hoʻonui ʻo ACE inhibitors ola i ka ola i loko o nā poʻe maʻi me ka hōʻeha puʻuwai a hoʻolohi i ka holomua o ka hōʻolo ʻana o ka ventricular hema i loko o nā mea maʻi ma hope o ka myocardial infarction me ka hōʻike ʻole ʻana i nā kauka o ka puʻuwai ʻole.

ʻO ka hoʻomakaʻana o ka hana i kahi hola 1. Hoʻoholo ʻia ka hopena kiʻekiʻe ma hope o 6-7 mau hola, lōʻihi - 24 mau hola. Me ka hypertension arterial, ʻike ʻia ka hopena i nā lā mua ma hope o ka hoʻomaka ʻana o ka hoʻōla, loaʻa kahi hopena paʻa ma hope o 1-2 mau mahina

Lapaʻau lāʻau

ʻO ka bioavailability o ka lāʻau he 25-50%, palupalu i nā protein plasma. Loaʻa ka C max i serum ma hope o 7 mau hola. ʻAʻohe ʻai i ka ʻai ʻana.

Hōʻike ʻia ka mana holoʻokoʻa ma o BBB a me ka loaʻaʻana o ka placental.

ʻAʻole di metabolys i ka Lysoril a hoʻololi ʻia e ka urine. Hoʻokuʻu ʻia ka hapanui o ka hapanui i ka wā o ka hana mua (kūpono ʻo T 1/2 - 12 mau hola), a ukali ʻia e ka mokulele mamao (T 1/2 e pili ana i 30 mau hola)

ʻLoe a me ke kākele

I loko. I pili aipuna iniha mua - 5 mg hoʻokahi manawa i ka lā, inā pono - a i ka 40 mg / lā. I hapa male ʻole: ʻo ka helu mua ma 2.5 mg, inā pono a hiki i 20 mg / lā. E pale aku i ke kāʻei o kahi kolohe ʻana o ka hoʻāla wai-electrolyte, diuretic therapy o ka renal maikaʻi ʻole, me ka renovascular hypertension, ʻo ka papa hana mua ka 1.25 mg / lā.

Nā hui like ʻana o nā hui nosological

Waiho i kāu manaʻo

Nā ʻIke Kūlana Kūlana, ‰

Lizoril hoʻopaʻa inoa

• P N014842 / 01-2003

ʻO ka pūnaewele mana o ka hui RLS ®. ʻO ka hoʻolaha nui o nā lāʻau lapaʻau a me nā huahana o ke kākāʻā o ka mea kūʻai aku i ka Pūnaewele Lūkia. Hāʻawi ka hua'ōlelo o Rlsnet.ru i nā mea hoʻohana me ke komo i nā ʻōkuhi, nā kumukūʻai a me nā wehewehe o nā lāʻau lapaʻau, nā mea hoʻoulu ai i nā meaʻai, nā pono olakino, nā lāʻau lapaʻau a me nā mea'ē aʻe. Hoʻokomo ka papa kuhikuhi i ka lāʻau lapaʻau e pili ana i ka ʻike a me ka puka o ka hoʻokuʻu, ka hana a ka lāʻau lapaʻau, ʻike mau no ka hoʻohana ʻana, contraindications, ka hopena o ka hopena, ka hoʻopili o ka lāʻau, nā ʻano hana o nā lāʻau lapaʻau, nā lāʻau lapaʻau. Aia i ka papa kuhikuhi ka lāʻau lapaʻau nā kumukūʻai no nā lāʻau a me nā huahana lāʻau lapaʻau ma Moscow a me nā kūlanakauhale Lūkini.

Ua pāpā ʻia ʻo ka hoʻoili ʻana, kope, hoʻolaha i ka ʻike me ka ʻole i ʻae ʻia ʻo RLS-Patent LLC.
I ka helu ʻana i nā ʻike ʻike i paʻi ʻia ma nā ʻaoʻao o ka pūnaewele www.rlsnet.ru, pono kahi loulou i ke kumu o ka ʻike.

ʻOi aku nā mea hoihoi aʻe

Iwai a aie ke dttla.

ʻAʻole ʻae ʻia ka hoʻohana ʻana i nā ʻoihana.

ʻO ka ʻike e hana no nā lāʻau lapaʻau.

Nā hōʻailona no ka hoʻohana ʻana

Hypertension Arterial (me ka hoʻohui pū ʻia i loko o ka maʻi), CHF, ka hoʻomaka ʻana o ka maʻi myocardial infarction ma ka maʻi hemodynamically paʻa (ma ke ʻano o ka hui hoʻohui ʻana).

Ma ke ʻāpana o ka hoʻohui ʻana no ka maʻi myocardial infarction (ma nā hola 24 mua, me ka hemodynamics paʻa).

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

I loko, me ka hypertension arterial - 5 mg hoʻokahi i ka lā. I ka hala ʻole o ka hopena, hoʻonui ʻia ka nui i kēlā me kēia mau lā 2-3 e 5 mg i ka awelika therapeutic awelika o 20-40 mg / lā (e hoʻonui ana i ka momona ma mua o 20 mg / lā maʻamau ʻaʻole alakaʻi i ka emi iki o ke kahe koko). ʻO ka palena kiʻekiʻe loa o kēlā me kēia lā he 80 mg.

Me ka HF - hoʻomaka me 2.5 mg hoʻokahi manawa, e ukali ʻia e ka hoʻonui hoʻomake wai o 2.5 mg ma hope o 3-5 lā.

I ka poʻe elemakule, ʻike pinepine ʻia ka hopena hypotensive lōʻihi i hōʻike ʻia, kahi i pili ʻia me ka hoʻēmi ʻana o ka helu lisinopril excretion (ua ʻōlelo ʻia e hoʻomaka i ka mālama ʻana me ka 2.5 mg / lā).

Ma ka hana ʻole o ka renal fail, hōʻalo ʻia ka cumulation me ka hoʻohaʻahaʻa ʻana i ka kānana o ka emi ma lalo o 50 ml / min (e hoʻemi ʻia ka nui o ka hōʻemi ma mua o 2 mau manawa, me CC ma lalo o 10 ml / min, pono ke hoʻemi ʻia ka nui ma ka 75%).

Me ka neʻe ʻana o ka hypertension arterial, hōʻike ʻia ka lōʻihi o ka mālama ʻana i ka mālama tamina i ka 10-15 mg / lā, me ka pohihihi ʻana o ka naʻau - ma ka 7.5-10 mg / lā.

Nā ʻōlelo kikoʻī

Pono ka mālama koʻikoʻi i ka wā e kuhikuhi ana i nā poʻe maʻi me ka stenosis aʻai o ka luaalateral renalal o ka stenosis kūʻai a i ʻole ka stenosis o ke aʻalopiki puʻuwai hoʻokahi (ʻoi aku ka hoʻonui ʻana o ka urea a me ka hana ʻana i loko o ke koko), nā mea maʻi me ka maʻi ʻalone coronary a me ka maʻi cerebrovascular, me ka puʻuwai o ka decompensated (hōʻemi hypotension, myocardial infarction, stroke). I ka poʻe maʻi me ka puʻuwai naʻau, hiki i ka arterial hypotension ke alakaʻi i ka hana ʻana i ka renal function.

Ke hoʻohana ʻana i nā lāʻau lapaʻau e hōʻemi i ke kahe o ke koko i nā mea maʻi me ka hoʻokela ākea a i ka wā he kanesa, hiki i ka lisinopril ke kāohi i ka hoʻokumu ʻana o ka angiotensin II, ka lua o ka hoʻokaʻawale ʻana i nā mea huna renin.

ʻAʻole paʻa ka palekana a me ka hopena o ka lisinopril i nā keiki.

Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, pono e hoʻopiʻi no ka nalowale o ka wai a me nā paʻakai.

Hoʻohana ʻo ka hoʻohana ʻana i ka wā hāpai a hiki ʻole, ke hiki ʻole ke hoʻohana i nā lāʻau lapaʻau ʻē aʻe a i ʻole lākou pono ʻole (pono e hoʻomaopopo ʻia ka mea maʻi i ka hopena o ka pēpē).

Nā nīnau, nā pane, nā loiloi e pili ana i ka lāʻau Lizoril

ʻO ka ʻikepili i hāʻawi ʻia e hana no nā lāʻau lapaʻau a me nā lāʻau lapaʻau. Aia nā ʻike e pili ana i ka lāʻau lapaʻau e pili ana i nā ʻōlelo i hoʻopili ʻia e ka mea hoʻopiʻi e ka mea hana. ʻAʻohe ʻikepili i hoʻopili ʻia ma kēia a ʻole kekahi ʻaoʻao o ka pūnaewele a mākou e hiki ke lawelawe ma kahi kūʻokoʻa no ka hoʻopiʻi pilikino i ka loea.

Loaʻa ka hopena

Mai ka pūnaehana cardiovascular: hoʻemi i ke koko, hōʻeha i ka umauma, ʻemi - hypotension orthostatic, tachycardia, bradycardia, ka helehelena o nā hōʻailona o ka naʻau puʻuwai, hoʻopuka i ka atrioventricular conduction.

Mai ka pūnaehana pīhoihoi: dizziness, hōʻeha, ka ʻōpū, ka ʻehaʻeha, ka puʻupuʻu hōʻoia ʻana o nā mākina o nā manamana lima a me nā lehelehe, ka hopena - ka hopena ashenika, ka hana ʻāʻī, haunaele.

Mai ka ʻeha o ka gastrointestinal: nausea, dyspepsia, anorexia, hoʻololi i ka ʻono, ʻeha o ka ʻōpū, ʻeha, huʻehu.

Hematopoietic o nā ʻāpana: leukopenia, thrombocytopenia, neutropenia, agranulocytosis, anemia (hoʻoneʻe hemoglobin, erythrocytopenia).

Mai ka papa hana hanu: dyspnea, bronchospasm, apnea.

Nā hui kūloko: the ede angeoneurotic, rashes kino, ʻeha.

Nā hōʻailona Laboratory: hyperkalemia, hyperuricemia, ʻaʻohe hana nui i hoʻonui ʻia ka "hepatic" transaminases, hyperbilibinemia.

ʻO kekahi, kōʻai maloʻo, hoʻohaʻahaʻa i ka potency, maʻamau - paʻakikī renal failed, arthralgia, myalgia, fever, edema (huaʻōlelo, nā lehelehe, limahana), hoʻomōhala i ka hoʻomohala o nā pūlima.

Nā hiʻohiʻona noi

Pono ka mālama koʻikoʻi i ka wā e kuhikuhi ana i nā poʻe maʻi me ka stenosis aʻai o ka luaalateral renalal o ka stenosis kūʻai a i ʻole ka stenosis o ke aʻalopiki puʻuwai hoʻokahi (ʻoi aku ka hoʻonui ʻana o ka urea a me ka hana ʻana i loko o ke koko), nā mea maʻi me ka maʻi ʻalone coronary a me ka maʻi cerebrovascular, me ka puʻuwai o ka decompensated (hōʻemi hypotension, myocardial infarction, stroke). I ka poʻe maʻi me ka puʻuwai naʻau, hiki i ka arterial hypotension ke alakaʻi i ka hana ʻana i ka renal function.

ʻO ka hoʻohaʻahaʻa pane ʻana i ke kahe o ke koko i ka wā e mālama pinepine ʻia nei me ka hoʻohaʻahaʻa i ka BCC i kumu ʻia e ka diuretic therapy, ka palena o ka paʻakai ʻana, ka dialysis, ʻōpū, a i ʻole ka luaʻi.

Hoʻolaha ʻia ka mālama ʻana me ka lisinopril i ka infarction myocardial kūʻē i ke kua o ke ʻano maʻamau o ka maʻi (thrombolytics, ASA, beta-blockers). Kūlike ʻole me ka lawelawe ʻo iv o ka nitroglycerin a i ʻole TTC nitroglycerin.

Ke hoʻohana ʻana i nā lāʻau lapaʻau e hōʻemi i ke kahe o ke koko i nā mea maʻi me ka hoʻokela ākea a i ka wā he kanesa, hiki i ka lisinopril ke kāohi i ka hoʻokumu ʻana o ka angiotensin II, ka lua o ka hoʻokaʻawale ʻana i nā mea huna renin. Ma mua o ka wehe ʻana (e komo pū ana me nā hana mālama niho), pono e hoʻomaopopo ʻia ka lāʻau lapaʻau / anesthetist e pili ana i ka hoʻohana ʻana o ka inhibitor ACE.

Wahi a nā hualoaʻa o nā haʻawina epidemiological, ua manaʻo ʻia ʻo ka hoʻohana like ʻana o nā inhibitor ACE a me ka insulin, a me ka lāʻau hypoglycemic waha, hiki ke alakaʻi i ka hanana o ka hypoglycemia. Loaʻa ka pilikia nui loa o ka hoʻolālā ʻana i nā hebedoma mua o ka hui pū ʻana, me ka poʻe maʻi i ka hana renal impaired. ʻO nā mea maʻi me ka maʻi maʻi e nānā pono i ka mālama glycemia, no ka mea i ka malama mua o ka maʻi me ka ACE inhibitor.

Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, pono e hoʻopiʻi no ka nalowale o ka wai a me nā paʻakai.

ʻO nā mea pilikia no ka hoʻomohala ʻana i ka hyperkalemia e pili ana i ka hoʻōla ʻole o ka renal, ka maʻi diabetes mellitus a me ka hoʻohana like ʻana o ka pāhare potassium-sparing (spironolactone, triamteren a amiloride), mākaukau a K + a i ʻole nā ​​mea paʻakai e loaʻa ana iā K +. Manaʻo ʻia ka nānā ʻana o kēlā me kēia manawa i ka ʻike ʻia ʻana o K + i ka plasma koko.

I nā mea maʻi e lawe ana i ka inhibitor ACE i ka wā desensitization i ka hymenopter, he meaʻilihune loa ia e kū mai ana kahi hanana hoʻoweliweli hoʻoweliweli. Pono e hoʻoleʻaleʻa iki i ka hoʻokaʻawale ʻana me kahi mea hoʻonaʻauao ACE ma mua o ka hoʻomaka ʻana i kahi papa o desensitization.

Hiki i nā hopena anaphylactoid ke hana ʻia a ʻo ka hemodialysis e hana ʻia me nā membranes nui kiʻekiʻe (me nā AN 69). Pono e noʻonoʻo pono i ka hoʻohana ʻana o kekahi ʻano ʻano like ʻole o ka membrane no nā dialysis a i ʻole nā ​​lāʻau anti antihypertensive.

ʻAʻole paʻa ka palekana a me ka hopena o ka lisinopril i nā keiki.