ʻO ka hoʻokuʻu aku no nā keiki Amoxiclav 125 mg: nā kauoha no ka hoʻohana ʻana
Nā ʻoniʻoni ʻoniʻoni kiʻi 500 mg / 125 mg, 875 mg / 125 mg
Hoʻokahi ʻia ma kahi papa pākuʻi ʻoniʻoni
mea waiwai: amoxicillin (as amoxicillin trihydrate) 500 mg a me ka acid clavulanic (as potassium clavulanate) 125 mg (no ka dosage 500 mg / 125 mg) aiʻole amoxicillin (e like me ka amoxicillin trihydrate) 875 mg a me ka acid clavulanic (as potassium clavulanate) 125 mg (no ka waihona ʻana o 875 mg / 125 mg).
nā mea hoʻowalewale: colloidal silicon dioxide, crospovidone anhydrous, sodium carboxymethyl cellulose, magnesium stearate, maina microcrystalline cellulose.
ʻano hoʻonohonoho kiʻi kiʻi: hydroxypropyl cellulose, ethyl cellulose, polysorbate, triethyl citrate, titanium dioxide (E 171), talc.
Hoʻopili ʻia nā papa ʻaina me kahi membrane kiʻi ʻoniʻoni a ʻulaʻula like ʻole paha, oblong, me kahi bevel, i kahakaha ʻia me "875/125" a me kahi hōʻailona ma kekahi ʻaoʻao, a ua kahakaha ʻia me "AMS" ma kēlā ʻaoʻao (no ke ʻano he 875 mg / 125 mg).
Phui kūpeʻa
Nā lāʻau lapaʻau antiibacterial no ka hoʻohanaʻana i nā ʻōnaehana. Nā lāʻau lapaʻau Beta-lactam - Penicillins. ʻO Penicillins i hui pū me ka beta-lactamase inhibitors. Clavulanic acid + amoxicillin.
ATX Code J01CR02
ʻO nā waiwai Pharmacological
Lapaʻau lāʻau
ʻO Amoxicillin a me clavulanic acid i hoʻopau ʻia ma kahi hopena wai i ke kumu pH physiological o ke kino. Hoʻopili maikaʻi ʻia nā māhele ʻelua ma hope o ka lawelawe waha. E kūpono e lawe i ka amoxicillin / clavulanic acid i ka wā a i ka hoʻomaka ʻana o kahi pāʻina. Ma hope o ka lawelawe waha, ka bioavailability o amoxicillin a me clavulanic acid ma kahi o 70%. ʻO ka poʻokela o ka launa o ka lāʻau i loko o ke kaila o nā mea like ʻelua like. Loaʻa ka ʻike Serum serum i ka hola 1 ma hope o ka hoʻokele ʻana.
Nā kikowaena serum o ka amoxicillin a me ka waila clavulanic i ka wā e lawe ana i ka hui pū ʻana o ka hoʻomākaukaux amoillicillin / clavulanic e like me nā mea i nānā ʻia me kahi lawelawe hoʻokaʻawale waha o ka nui o ka nui o ka amoxicillin a me ka clavulanic acid.
Ma kahi o 25% o ka nui o ka huina clavulanic a me 18% o ka amoxicillin e hoʻopaʻa ai i nā protein plasma. ʻO ka nui o ka hoʻolaha no ka hoʻokolohua waha o ka lāʻau lapaʻau e pili ana i ka 0.3-0.4 l / kg o ka amoxicillin a me 0.2 l / kg o ka waikawa clavulanic.
Ma hope o ka hoʻonaninani intravenous, ua loaʻa nā amoxicillin a me clavulanic acid i loko o ka pālaʻi o ka ʻōpū, ka pona o ka ʻōpū o ka ʻōpū, ka ʻili, ka momona, ka ʻaoʻao o ka ʻōpū, nā synovial a me nā peritoneal wai, ka ʻili a me nā pa. Amoxicillin i komo hewa i loko o ka wai o ka cerebrospinal.
ʻO Amoxicillin a me clavulanic acid e hoʻōla i ka paepae placental. Ua hoʻoili ʻia nā mea ʻelua i ka waiū umauma.
ʻO Amoxicillin i hoʻokaʻawale ʻia i loko o ka urine ma ke ʻano o ka waikawa penicillic acid i loko o nā huina o ka 10-25% o ka pākuʻi mua. Hoʻomomi ka huika Clavulanic i loko o ke kino a hoʻopiʻi ʻia i loko o ka pāʻai a me nā mea ʻai, a me ke ʻano o ka carbon dioxide me ka ea hanu.
ʻO ka hapalua hapalua hapalua o nā amoxicillin / clavulanic acid ka mea ma kahi o 1 hola, a ʻo ka nui awelika o ka welu he 25 l / h. Ma kahi o 60-70% o ka amoxicillin a me 40-65% o ka clavulanic acid e hoʻopiʻi ʻole i ka loli i ka urine i ka 6 mau hola mua ma hope o ka lawe ʻana i hoʻokahi lemona o nā papa waika amoxicillin / clavulanic. I loko o nā noiʻi like ʻole, ua loaʻa ka 50-85% o amoxicillin a me 27-60% o ka clavulanic acid e hoʻopio ʻia i loko o ka urine i loko o 24 mau hola. ʻO ka nui loa o ka waikawa clavulanic i hoʻopili ʻia i ka wā 2 mau hola ma hope o ka noi.
ʻO ka hoʻohana like ʻana o ka probenecid e hoʻolei ana i ka hoʻokuʻu o ka amoxicillin, akā ʻaʻole i pili kēia lāʻau i ka excretion o ka clavulanic acid ma o nā keiki.
ʻO ka hapalua o ka ola o ka amoxicillin e like me nā keiki i hala 3 mau makahiki a i 2 mau makahiki, i nā keiki a me nā pākeke. I ka hoʻonoho ʻana i ka lāʻau lapaʻau i nā keiki liʻiliʻi loa (me nā pēpē preterm) i nā hebedoma mua o ke ola, pono ʻole e lawelawe ʻia ka lāʻau lapaʻau ma mua o ʻelua mau manawa i ka lā, e pili pū ana me ka nui o ke ala o ka renal excretion ma nā keiki. Ma muli o ka nui o ka nui o nā mea maʻi e ʻeha paha mai ka maʻi papaha, pono ke hoʻohana ʻia ʻo Amoxiclav 2X me ka akahele ma kēia ʻōpū o nā maʻi, akā e nānā ʻia nā hana o ka renal inā pono.
ʻO ka huina piha o ka amoxicillin / clavulanic acid i ka plasma e hoʻemi ana i ka kūlike pololei i ka hoʻemi ʻana o ka hana ʻoi. ʻOi ka hoʻohaʻahaʻa i ka hoʻopale amoxicillin e hōʻike hou ʻia i ka hoʻohālikelike clavulanic, no ka mea nui ka nui o ka amoxicillin e hoʻopili ʻia ma o nā keiki. No laila, i ke kuhikuhi ʻana i ka lāʻau lapaʻau i nā mea maʻi me ka pilikia ʻole, pono ke hoʻoponopono ʻia e pale ai i ka hōʻiliʻili nui ʻana o nā amoxicillin a mālama i ka pae pono o ka waila clavulanic.
Ke koho ʻana i ka lāʻau lapaʻau i nā mea maʻi me ka nele o ka puʻuwai, pono e hoʻomaʻamaʻa i ka wā e koho ana i kahi pākala a mālama pono i nā hana o ka ate.
Lapaʻau lāʻau
ʻO Amoxicillin kahi antibiotic semi-synthetic mai ka hui penicillin (beta-lactam antibiotic) e kāohi ana i hoʻokahi mau mea hou aʻe (a i kapa pinepine ʻia ʻo penicillin-nakinaki pū) ka mea i komo i ka biosynthesis o peptidoglycan, he mea nui ka hana hiʻona o ka paia o ka pa selia. Ke hōʻike nei i ka syntept peptidoglycan e alakaʻi i ka nāwaliwali o ka paia o ke kelepona, maʻamau ʻia e ka cell lysis a me ka make cell.
Ua luku ʻia ʻo Amoxicillin e ka beta-lactamases i kū ʻia e nā pōʻino kū kūpaʻa, a, no laila, ʻaʻole i komo ka sproxionil o nā hanaxicillin wale nō me ka hana ʻana i kēia mau enzymes.
ʻO Clavulanic waikawa he beta-lactam i hoʻopili pili me nā penicillins. Hoʻopili ia i kekahi mau beta-lactamases, ma laila e pale ai i ka hoʻopono ʻole o ka amoxicillin, a hoʻonui i kona ʻano. Clavulanic acid ʻaʻole loa he hopena o ka maʻi antibacterial koʻikoʻi.
ʻO ka manawa ma luna o ka manawa liʻiliʻi o ka pipili liʻiliʻi liʻiliʻi (T> IPC) i manaʻo ʻia ʻo ka mea nui o ka hopena o ka hopena o ka hopenaxicillin.
ʻO nā papa hana kino ʻelua i kū kūʻē aku ai i ka amoxicillin a me nā waila clavulanic:
kaohi ʻana ma o bacterial beta-lactamases ʻaʻole i paʻa i ka acid clavulanic, me nā papa B, C a me D.
kahi loli i nā protein paʻa penicillin-binding, e hōʻemi ana i ka pilina o ka huakaʻi antibacterial i ka pathogen kiko.
ʻO ka hemahema o nā bakiʻi a i ʻole nā hana paha o ka pump efflux (ʻōnaehana ʻoihana) ke kumu a hoʻomau i ka pale ʻana i nā kūmole, ʻoi aku ka nui o ka bacteria-Negative.
ʻO nā palena palena o ka MIC no ka amoxicillin / clavulanic acid ka mea i hoʻoholo ʻia e ke Komite ʻEulopa no ka hōʻike ʻana i ka Antimicrobial Sensitivity (EUCAST).
Nā hana hana i ka hana
ʻO Amoxicillin kahi antibiotic ākea ākea ākea me ka hana e kūʻē i nā microorganisms gram-maikaʻi a me ka gram-negatif. I ka manawa like, hiki i ka amoxicillin ke hōʻemi nei i ka luku, e nā beta-lactamases, a no laila ke kahe mai o ka hana o ka amoxicillin e hoʻopili i nā microorganism e hana nei i kēia enzyme.
ʻO Clavulanic acid, kahi beta-lactamase inhibitor struktally pili i penicillins, hiki i ka hana ke hana i ka nui o nā beta-lactamases i loaʻa i ka penicillin a me nā microorganism kūloko cephalosporin pale. Loaʻa i ka waikawa Clavulanic e kūpaʻa ana i ka plasmid beta-lactamases, ka mea maʻamau ke kū nei i ka pale ʻana i ka maʻi bacterial, ʻaʻole ia he hopena me ka type chromosome beta-lactamases, ʻaʻole i pale ʻia e ka clavulanic acid.
ʻO ka heleʻana o ka acid clavulanic i ka mākaukau e mālama ana i ka amoxicillin mai ka luku ʻana e nā enzymes - beta-lactamases, kahi e hiki ai ke hoʻonui i ka lolo o ka antibacterial o amoxicillin.
ʻO Amoxiclav ka hana antibacterial i kēia microorganisms i kēia:
- Anaerobes gram-positive (Staphylococcus aureus, pneumococcus, pyogenic streptococcus, nā mea ʻē aʻe o ka staphylococcus aureus a me streptococcus, clostridia, peptococcus),
- Anaerobes Gram-negative (bacteria bakya, bacteria o nā hua mea Enterobacter, Klebsiella, Moraxella cataralis, Bordetella, Salmonella, Shigella, Vibrio cholera).
Ma muli o ke kumu o nā kaha o nā huelo i luna e hana i ka beta-lactamase, hana kēia iā lākou i ka intoxitive o Amoxicillin monotherapy.
Lapaʻau lāʻau
Hoʻopili maikaʻi ʻia nā ʻano mea ikaika ʻelua, me ka manaʻo o ka ʻono o ka meaʻai. Aia ke kaila o ka plasma nui loa i hoʻokahi hola ma hope o ka lawe ʻana i ka lāʻau (Cmax no amoxicillin - 3-12 μg / ml, Cmax no ka clavulanic acid - 2 μg / ml.
Hoʻomaʻi maikaʻi ʻia nā ʻāpana Amoxiclav i ka pleura, parietal, nā wai synovial, nā mea huna bronchial, nā huna ʻona a ke kanal, ka lawena, a me nā ʻili o ke kino (i loko o nā pūpū, palatine tonsils, waena pepeiao, ovaries, uterus, ate, prostate gland, muscle tissue, gall blderder ) ʻAʻole hiki i ka lāʻau lapaʻau ke komo i loko o ka pani o ka lolo-lolo (me nā meninges non-inflamed). Penetrates ma o ka paʻana placental, i loko o nā mea i hoʻopaʻa ʻia me ka waiū umauma. Hoʻohālikelike ia i ka protein protein, amoxicillin trihydrate hoʻokaʻawale decomposes, clavulanic acid - piha loa.
Hoʻopau ʻia ka lāʻau lapaʻau e nā keiki aneane ʻaʻole i loli. Hoʻopili ʻia nā liʻiliʻi liʻiliʻi e nā māmā a ma o nā ʻōpū. ʻO ka hapalua hapalua kahi 1-1,5 hola.
Hoʻopili ʻia ʻo Amoxicillin e nā keiki i aneane e loli a ka huna ʻia o ka tubular a me ka filtration glomerular. Hiki ke hoʻopaneʻe ʻia ka liʻiliʻi ma o nā ʻōpū a me nā ʻōpū. ʻO T1 / 2 o ka amoxicillin a me ka waikawa clavulanic he 1-1,5 hola. Ma kahi hana hoʻopili nui, hoʻonui ʻia no ka amoxicillin a i nā hola 7,5, no ka waikawa clavulanic - a hiki i nā hola 4. Hoʻokuʻu ʻia nā ʻaoʻao ʻelua i ka wā o hemodialysis.
Nā hōʻailona no ka hoʻohana ʻana
ʻO ka Amoxiclav kahi lāʻau lapaʻau antibacterial, hōʻike ʻia no ka mālamaʻana i nā maʻi maʻi maʻi i hoʻoiho ʻia e nā maʻi i mālama ʻia i ka penicillin a me nā kūmole.
- nā hopena o ka ʻōpū hanu o luna a me nā mea komo ENT (ke kumu a me ka sinusitis kūloko, a me ke kaniitisitis otitis media, ka maʻi o ka pharyngeal, tonsillitis, pharyngitis),
- ʻōpū o ka hanu haʻahaʻa (ʻehaʻeha bronchitis me ka superinfection bakalula, bronchitis paʻa, pneumonia),
- nā maʻi urinary tract (e.g., cystitis, urethritis, pyelonephritis),
- nā maʻi āpau i ka gynecology,
- ka hopena o ka ʻili a me nā kiko palupalu, e komo pū me nā holoholona a me ke kanaka.
- nā iwi a me nā hui pili kino,
- biliary tract infection (cholecystitis, cholangitis),
- maʻi maʻi odontogenic.
ʻLoe a me ke kākele
I loko. Hoʻonohonoho ka dosage dosage i kū hoʻokahi i ka makahiki, ke kino, ke ʻano hana a ka mea maʻi a me ka nui o ka maʻi.
ʻO ka mahele o kēlā me kēia lā o ka hoʻokuʻu ʻia ʻana he 125 mg + 31.25 mg (e hoʻomaʻamaʻa i nā dosa kūpono, kahi pipette puka mua 5 ml me kahi ʻōmole 0.1 ml a i kahi kīnā wai 5 ml me nā hōʻailona annular i loko o ka lua o 2.5 ml i kau ʻia i kēlā me kēia pūpū a 5 ml).
Nā kiʻi 3D
| Nā papa hana ʻulaʻī | 1 kōpō. |
| nā mea waiwai (core): | |
| amoxicillin (i ke ʻano o kahi trihydrate) | 250 mg |
| kaʻiole clavulanic (ma ke ʻano o ka paʻakai paʻakai) | 125 mg |
| nā mea hoʻowalewale: ʻO ke kiko silika colloidal - 5.4 mg, crospovidone - 27,4 mg, criumarmellose sodium - 27.4 mg, magnesium stearate - 12 mg, talc - 13.4 mg, MCC - a hiki i ka 650 mg | |
| make a film hypromellose - 14.378 mg, ethyl cellulose 0.702 mg, polysorbate 80 - 0.78 mg, triethyl citrate - 0.793 mg, titanium dioxide - 7.605 mg, talc - 1.742 mg |
| Nā papa hana ʻulaʻī | 1 kōpō. |
| nā mea waiwai (core): | |
| amoxicillin (i ke ʻano o kahi trihydrate) | 500 mg |
| kaʻiole clavulanic (ma ke ʻano o ka paʻakai paʻakai) | 125 mg |
| nā mea hoʻowalewale: colloidal silicon dioxide - 9 mg, crospovidone - 45 mg, sodium croscarmellose - 35 mg, magnesium stearate - 20 mg, MCC - a hiki i 1060 mg | |
| make a film hypromellose - 17.696 mg, ethyl cellulose - 0.864 mg, polysorbate 80 - 0.96 mg, triethyl citrate - 0.976 mg, titanium dioxide - 9.36 mg, talc - 2.144 mg |
| Nā papa hana ʻulaʻī | 1 kōpō. |
| nā mea waiwai (core): | |
| amoxicillin (i ke ʻano o kahi trihydrate) | 875 mg |
| kaʻiole clavulanic (ma ke ʻano o ka paʻakai paʻakai) | 125 mg |
| nā mea hoʻowalewale: colloidal silicon dioxide - 12 mg, crospovidone - 61 mg, sodium croscarmellose - 47 mg, magnesium stearate - 17.22 mg, MCC - a hiki i 1435 mg | |
| make a film hypromellose - 23.226 mg, ethyl cellulose - 1.134 mg, polysorbate 80 - 1.26 mg, triethyl citrate - 1.28 mg, titanium dioxide - 12.286 mg, talc - 2.814 mg |
| ʻO ka pauka no ka pohō o ka waha | 5 ml lolo |
| mea waiwai: | |
| amoxicillin (i ke ʻano o kahi trihydrate) | 125 mg |
| kaʻiole clavulanic (ma ke ʻano o ka paʻakai paʻakai) | 31.25 mg |
| nā mea hoʻowalewale: citric acid (anhydrous) - 2.167 mg, sodium citrate (anhydrous) - 8.335 mg, sodium benzoate - 2.085 mg, MCC a me ka sodium carmellose - 28.1 mg, xanthan gum - 10 mg, colloidal silicon dioxide - 16.667 mg, silicon dioxide - 0.217 g, sodium saccharinate - 5.5 mg, mannitol - 1250 mg, ʻōpala ʻōpala - 15 mg |
| ʻO ka pauka no ka pohō o ka waha | 5 ml lolo |
| mea waiwai: | |
| amoxicillin (i ke ʻano o kahi trihydrate) | 250 mg |
| kaʻiole clavulanic (ma ke ʻano o ka paʻakai paʻakai) | 62.5 mg |
| nā mea hoʻowalewale: citric acid (anhydrous) - 2.167 mg, sodium citrate (anhydrous) - 8.335 mg, sodium benzoate - 2.085 mg, MCC a me ka sodium carmellose - 28.1 mg, xanthan gum - 10 mg, colloidal silicon dioxide - 16.667 mg, silicon dioxide - 0.217 g, sodium saccharinate - 5.5 mg, mannitol - 1250 mg, wild cherry flavor - 4 mg |
| ʻO ka pauka no ka pohō o ka waha | 5 ml lolo |
| mea waiwai: | |
| amoxicillin (i ke ʻano o kahi trihydrate) | 400 mg |
| kaʻiole clavulanic (ma ke ʻano o ka paʻakai paʻakai) | 57 mg |
| nā mea hoʻowalewale: citric acid (anhydrous) - 2.694 mg, sodium citrate (anhydrous) - 8.335 mg, MCC a me ka carmellose sodium - 28.1 mg, xanthan gum - 10 mg, colloidal silicon dioxide - 16.667 mg, silicon dioxide - 0.217 g, wild cherry flavor - 4 mg, ka lemona lemon - 4 mg, sodium saccharinate - 5.5 mg, mannitol - a hiki i 1250 mg |
| ʻO ka paukahi no ka hoʻonā ʻana no ka hoʻokele intravenous | 1 fl. |
| mea waiwai: | |
| amoxicillin (i ke ʻano o ka paʻakai sodium) | 500 mg |
| kaʻiole clavulanic (ma ke ʻano o ka paʻakai paʻakai) | 100 mg |
| ʻO ka paukahi no ka hoʻonā ʻana no ka hoʻokele intravenous | 1 fl. |
| mea waiwai: | |
| amoxicillin (i ke ʻano o ka paʻakai sodium) | 1000 mg |
| clavulanic acid (ma ke ʻano o ka paʻakai pākela). | 200 mg |
| Nā pale papa | 1 kōpō. |
| mea waiwai: | |
| amoxicillin trihydrate | 574 mg |
| (e like me 500 mg o ka amoxicillin) | |
| pā clavulanate | 148.87 mg |
| (e like me 125 mg o ka clavulanic acid) | |
| nā mea hoʻowalewale: Ka hoʻohuihiwa pōpilikia - 26 mg, ka ʻono ʻono i ka wai - 26 mg, aspartame - 6,5 mg, colloidal silicon dioxide anhydrous - 13 mg, hao (III) oxide melemele (E172) - 3.5 mg, talc - 13 mg, castor nā ʻaila hydrogenated - 26 mg, silikino-me MCC - a hiki i 1300 mg |
| Nā pale papa | 1 kōpō. |
| mea waiwai: | |
| amoxicillin trihydrate | 1004.50 mg |
| (e like me 875 mg o ka amoxicillin) | |
| pā clavulanate | 148.87 mg |
| (e like me 125 mg o ka clavulanic acid) | |
| nā mea hoʻowalewale: Ka hoʻohuihui pōpilikia - 38 mg, ka ʻono ʻono i ka wai - 38 mg, aspartame - 9.5 mg, colloidal silicon dioxide anhydrous - 18 mg, hao (III) oxide melemele (E172) - 5.13 mg, talc - 18 mg, castor nā ʻaila hydrogenated - 36 mg, silicon-piha MCC - i ka 1940 mg |
ʻO ka wehewehe ʻana i ke ʻano dosis
250 + 125 mau papa pā: ke keʻokeʻo a ʻokoʻa paha keʻokeʻo paha, oblong, octagonal, biconvex, film-coated, me nā paʻi ʻana o "250/125" ma kekahi ʻaoʻao a "AMC" ma kēlā ʻaoʻao.
500 + 125 mg papa: keʻokeʻo a ʻokoʻa paha keʻokeʻo, ʻānō, biconvex, film-coated.
Nā Papa 875 + 125 mg: ke keʻokeʻo a ʻokeʻoke paha keʻokeʻo paha, oblong, biconvex, kāwele ʻia, ʻoniʻoni me nā panina a me nā manaʻo "875" a me "125" ma kekahi ʻaoʻao a "AMC" ma kēlā ʻaoʻao.
Ka nānā ʻana i kahi kink: kaomi melemele.
ʻO ka pauka no ka hoʻokō ʻana i ka hoʻoponopono waha: pauka mai keʻokeʻo a hiki i keʻokeʻo keʻokeʻo. ʻO ka pēpē i pau nei he hana hoʻoneʻe homogeneous mai kahi keʻokeʻo a keʻokeʻo.
ʻO ka pauka no ka hoʻomākaukau ʻana i kahi hopena no ka ʻoila iv: mai keokeo a hiki i keʻokeʻo ke ʻano.
Loaʻa nā papa ʻaina: oblong, octagonal, ʻulaʻula kukui me kahi ulana o kahi ʻulaʻula, me kahi manamana fruity.
Lapaʻau lāʻau
ʻO Amoxiclav ® kahi hui o ka amoxicillin a me ka waikawa clavulanic.
ʻO Amoxicillin kahi penicillin semisynthetic (beta-lactam antibiotic) e kāohi ana i hoʻokahi mau mea hou aʻe (a i kapa pinepine ʻia ʻo ia nā penikillin-binding protein, PSB) i ka biosynthesis o peptidoglycan, he mea hoʻohui i ka paia o nā pā cell bacterial. Ke hōʻike nei o ka syntept peptidoglycan e alakaʻi i ka nalowale o ka ikaika o ka paia pā, nāna e hoʻonā i ka lysis a me ka make o nā mea microorganism.
Ua luku ʻia ʻo Amoxicillin e ka hana a beta-lactamases i hoʻohālikelike ʻia e nā pale kūpaʻa, no laila ʻaʻole i komo ka sprax o nā hanaxicillin i nā microorganism e hana i kēia mau enzymes.
ʻO Clavulanic waikawa he beta-lactam i hoʻopili pili me nā penicillins. Mālama i kekahi mau beta-lactamases, ma laila e pale ai i ka hoʻopono ʻole o ka amoxicillin a hoʻonui i kona ʻano o nā hana, ʻoi aku nā ʻano o nā bacteria i kū maʻamau i ka amoxicillin, a me nā penicillins a me nā cephalosporins. Clavulanic acid ʻaʻole loa he hopena o ka maʻi antibacterial koʻikoʻi.
Loaʻa iā Amoxiclav ® kahi hopena bactericidal i vivo i nā microorganisms i kēia:
- aerobes maikaʻi-gram Staphylococcus aureus *, Streptococcus pneumoniae, Streptococcus pyogenes,
- kalama aerobes maikaʻi ʻole - Enterobacter spp. **, Escherichia coli *, Haemophilus influenzae *ʻano o ke ʻano ʻano Klebsiella *, Moraxella catarrhalis * (Branhamella catarrhalis).
Loaʻa iā Amoxiclav ® kahi hopena bactericidal i loko o vitro ma nā microorganism e hiki mai ana (eia nō naʻe, ʻaʻole ʻike ka ʻike koʻikoʻi).
- aerobes maikaʻi-gram Bacillis anthracis *ʻano o ke ʻano ʻano Corynebacterium, Enterococcus faecalis *, Enterococcus faecium *, Listeria monocytogenes, Nocardia asteroidescoagulase-hewa staphylococci * (komo Staphylococcus epidermidis), Streptococcus agalactiae, nā ʻano ʻē aʻe o ka ʻano ʻano Streptococcus, Streptococcus viridans,
- anaerobes-gram-maikaʻi - pili i ka iwi ʻO Clostridiumʻano o ke ʻano ʻano ʻĀina Peptococcusʻano o ke ʻano ʻano ʻĀpana Peptostreptococcus,
- kalama aerobes maikaʻi ʻole - ʻO Bordetella pertussisʻano o ke ʻano ʻano Brucella, Gardnerella vaginalis, Helicobacter pyloriʻano o ke ʻano ʻano ʻO Legionella, Neisseria gonorrhoeae *, Neisseria meningitidis *, ʻo Pasteurella multocida, Proteus mirabilis *, Proteus vulgaris *ʻano o ke ʻano ʻano Salmonella *ʻano o ke ʻano ʻano Shigella *, ʻo Vibrio cholerae, Yersinia enterocolitica *,
- anaerobes - gram-negatif - ulu i ka iʻa Huakini * (komo Hoʻokomo nā huapili) nā ʻanoʻano o ke ʻanoʻaoʻao Hulaimo *,
- - - Borrelia burgdorferi, Chlamydia spp., Leptospira icterohaemorrhagiae, Treponema pallidum.
* Hoʻokumu kekahi o kēia mau ʻano o nā bakteri i ka beta-lactamases, kahi i hāʻawi ʻia i ko lākou insensitivity i ka amoxicillin monotherapy.
** Kūpono ka hapanui o kēia mau huakini i ka hui pū ʻana o ka acidxxillillin / clavulanic i loko o vitro akā naʻe, ua hōʻike ʻia ka maikaʻi o ke lapaʻau o kēia hui ʻana i ka mālama ʻana i nā maʻi o ka maʻi urinary i kumu ʻia e kēia mau uaua.
Nā ʻōmole Amoxiclav ®
No nā palapala hoʻoponopono āpau
Nā maʻi ʻeha e hōʻake ʻia e nā ʻōpala hikiʻole i nā microorganisms:
nā ʻōpū hanu a me nā kumumea ENT (e pili ana i ka sinusitis a me ke keaka sinusitis, nā maʻi a me nā maʻi otitis paʻa ʻole, nā maʻi pharyngeal, tonsillitis, pharyngitis),
ʻōpū o ka ʻōpū hanu haʻahaʻa (me ka hoʻopuka ʻana o ka bronchitis nui me ka superinfection bakalula, bronchitis paʻa, pneumonia),
nā urinary tract (e.g. cystitis, urethritis, pyelonephritis),
ʻili a me nā ʻili palupalu, me nā kiko a ke kanaka a me nā holoholona.
iwi a me ka pili paʻa
nā dile bile (cholecystitis, cholangitis),
No ka pauku no ka hoʻomākaukau o kahi hopena no ka mālama ʻo iv
ʻōpū mai ka ʻōpū
nā maʻi hoʻonaninani (gonorrhea, mild chancre),
ka pale ʻana o nā maʻi ma hope o ka wehe ʻana.
Nā Hoʻohui
hypersensitivity i nā māhele o ka lāʻau lapaʻau,
hypersensitivity o penicillins, cephalosporins a me nā beta-lactam antibiotics hou i loko o ka anamnesis,
ka mōʻaukala o ka jaundice cholestatic a me / a mai 'ole o ka pulu hana o ka puhā i hoʻomohala ʻia e ka hoʻokō o ka amoxicillin / clavulanic acid,
ka maʻi mononucleosis hopohopo a me ka maʻi lymphocytic,
No nā papa hoʻoneʻe ʻia ʻo Amoxiclav ® Quicktab hoʻohui hou
nā keiki ma lalo o 12 a kaupaona paha e emi iho ma lalo o 40 kg.
pilikia hāmeʻa (Cl creatinine, gastrointestinal tract, hōʻeha ate, hōʻiliʻili o ka renal maʻi nui, hapai, lactation, hana like me nā anticoagulants.
ʻŌpū a me ka lactation
I ka wā hāpai a me ka lactation, ke hoʻohana wale ʻia ʻo Amoxiclav ® inā pono ka pōmaikaʻi i manaʻo ʻia i ka makuahine ma mua o ka nui o ka hiki i ka pūpū a me ke keiki.
Hiki ke kuhikuhi ʻia ʻo Amoxiclav ® Quicktab i ka wā hāpai a inā he mau ʻike maopopo.
ʻO Amoxicillin a me clavulanic acid i kahi liʻiliʻi liʻiliʻi e komo i loko o ka waiū umauma.
Nā hopena hopena
ʻO nā papa kiʻi ʻoniʻoni ʻo Amoxiclav ® a me ka pauka no ka hoʻomākaukau ʻana i kahi hoʻonā no ka hoʻokō iv
Mai ka pūnaehana hana ʻana: ka nalo ʻana o ka ʻono, ka ʻōpū, ka luaʻi ʻana, ka ʻeha o ka ʻōpū, ka ʻōpū, ka hōʻeha, ka leʻomaʻi, ka glossitis, ʻulaʻula "lauoho", ʻeleʻele o ka enamel niho, colitis hemorrhagic (e ulu pū ka hope ma hope o ka lāʻau), enterocolitis, pseudomembranous colitis, hana ʻole i ka hana ate, hoʻonui ʻia ALT, AST, phosphatase alkaline a me / a i ʻole nā pae bilirubin plasma, hōʻeha o ka ate (ʻoi aku ka nui i ka poʻe ʻelemakule, nā kāne, me ka hoʻomanawanui lōʻihi), jaundice cholestatic, hepatitis.
Nā maʻi kūwaha: pruritus, urticaria, erythematous rashes, erythema multiforme exudative, angioedema, anaphylactic shock, allergic vasculitis, exfoliative dermatitis, Stevens-Johnson syndrome, ulana maoli exanthematous pustulosis, he ʻāhane e like me ka maʻi serum, epidermis toxic.
Mai ka pūnaehana hemopoietic a me ka ʻōnaehana lymphatic: leukopenia hiki mai (me ka neutropenia), thrombocytopenia, hemolytic anemia, hoʻololi hou ʻia i ka PV (i ka wā i hoʻohana pū ʻia me anticoagulants), hoʻonui ʻia i ka manawa koko, eosinophilia, pancytopenia, thrombocytosis, agranulocytosis.
Mai ka ʻaoʻao o ka pīkī laha waena: dizziness, headache, convulsions (hiki i nā mea maʻi me ka hana renal impaired i ka wā a lawe i nā kiʻekiʻe kiʻekiʻe o ka lāʻau).
Mai ka urinary system: interstitial nephritis, crystalluria, hematuria.
Nā ʻili: kandidiasis a me nā ʻano ʻē aʻe o ka superinfection.
No nā papa hana ʻoniʻoni polū, ka pauka no ka hoʻopiʻi ʻana i ka waha, ka pauka no ka hoʻonā o nā waha ma kahi o ka pane ʻana
Mai ka ʻaoʻao o ka pīkī laha waena: pālahalahaʻai. Fehe o ka hopohopo, lokoʻa, loli, hoʻāla.
ʻO Amoxiclav ® Quicktab a me ka pauka me Amoxiclav ® no ka hoʻokuʻu ʻana i ka waha
Mai nā ʻekopa hemopoietic a me ka ʻōnaehana lymphatic: leukopenia līwī (hiki i ke neutropenia), thrombocytopenia, loa pinepine - eosinophilia, thrombocytosis, hiki i ka agranulocytosis, hiki ke hoʻonui i ka manawa koko a me ka piʻi hou i loko o PV, anemia, a me hoʻohālikelike hemolytic anemia.
Mai ka pānaʻi: ʻike pinepine ʻole ka frequency - angioedema, reaksi anaphylactic, vasculitis allergic, he ʻeha e like me ka maʻi serum.
Mai ka ʻōnaehana hoʻonāukiuki: - ka ʻeha, ka poʻomanaʻo, ʻehaʻeha - hiki i ka insomnia, ke kaumaha, hopohopo, luhi, loli, hoʻāla ʻia ka hoʻōla, hoʻoliʻi, hiki i ka hoʻokau ʻana ke hele i nā maʻi me ka hana ʻole o ka papaha, a me ka poʻe e loaʻa nā kaha kiʻekiʻe o ka lāʻau lapaʻau.
Mai ka palaki kuʻekuʻe: pinepine - ka nalowale i ka makemake, nilo, ka luaʻi ʻana, ka ʻeha ʻana o ka maʻi. ʻIke pinepine ʻia ke ʻano loiloi i ka wā e kau ai nā kaha kiʻekiʻe. Inā hoʻopaʻa ʻia nā maʻi gastrointestinal, hiki ke hoʻopau ʻia inā ke lawe ʻia ka lāʻau i ka hoʻomaka ʻana o ka pāʻina, pinepine - hoʻoweliweli ka huhū, ʻike pinepine ʻia nā maʻi o ka antibiotic e hoʻoulu ʻia e ka antibiotics (me ka pseudomembranous a me ka hemorrhagic colitis), nā lehelehe ʻeleʻele, gastritis stomatitis. I nā keiki, ʻike liʻiliʻi ka ʻili o ka papale papa o ka niho enamel. E mālama ana ka mālama waha i ka pale ʻana i ka enamel niho.
Ma ka ʻāpana o ka ʻili. ka pinepine - ka ʻāʻī o ka ʻili, ka huhū, ka urticaria, līkeke - erythema e ka multiforme exudative, ʻike pinepine ʻole - Stevens-Johnson syndrome, necrolysis epidermal toxic, ʻekahi dermatitis exousoli, ulu exanthematous pustulosis.
Mai ka urinary system: loa iino loa - crystalluria, interstitial nephritis, hematuria.
Ma ka ʻāpana o ka ate a me ka pēpē biliary: pinepine - i hoʻonui ʻia ka hana o ALT a me / a AST (ʻike ʻia kēia ʻike ʻana i nā mea maʻi e loaʻa ana i ka hoʻomehana maʻi beta-lactam, akā ʻike ʻia kona ʻano koʻikoʻi), ʻO nā hanana ʻino loa mai ka leʻaleʻa i nānā nui ʻia i nā kāne a me nā mea maʻi a hiki i ka pili paha me ka lōʻihi o ka maʻi. ʻO nā hanana ʻino loa i nānā ʻole i nā keiki.
ʻO nā hōʻailona a me nā hōʻailona i hele pinepine ʻia ma ke a ma hope iho o ka pau ʻana o ka hoʻōla, eia naʻe i kekahi mau hihia ʻaʻole paha e ʻike ʻia no kekahi mau hebedoma ma hope o ka pau ʻana o ka lapaʻau. ʻO nā hanana ʻinoʻino ke hoʻololi pinepine. Hiki i nā pilikia hōʻeha mai ka luhi ka maʻi paʻakikī, ma nā hihia koʻikoʻi loa i hōʻike ʻia nā hopena o nā hopena hōʻeha. I ka aneane āpau, ʻo kēia mau mea maʻi me ka pathology concomitant koʻikoʻi a i ʻole nā mea maʻi e loaʻa ana i nā lāʻau lapaʻau hepatotoxic. Kuhi loa - hoʻonui i ka hana o ka phosphatase alkaline, hoʻonui bilirubin, hepatitis, jaundice cholestatic (ʻike ʻia me ka concomitant therapy me nā penicillins a me cephalosporins).
Nā ʻili: pinepine - kandidiasis o ka ʻili a me nā membrane mucous, ʻaʻole maopopo ka ʻike i ke ala - ka ulu ʻana o nā microorganisms insensitive.
Hoʻohui
No nā palapala hoʻoponopono āpau
Hoʻokomo i nā hoʻonaninani, nā glucosamine, laxatives, aminoglycosides i ka hoʻopili ʻana aku, hoʻonui i ka hoʻohuihui ascorbic.
Diuretics, allopurinol, phenylbutazone, NSAIDs a me nā lāʻau lapaʻau ʻē aʻe e kāohi ana i ka huna ʻana o tubular (probenecid) e hoʻonui i ka kūpaʻa o ka amoxicillin (clavulanic acid e hoʻōla nui ʻia e ka glomerular filtration).
ʻO ka hoʻohana like ʻana o ka Amoxiclav ® a me ka methotrexate e hoʻonui i ka pakanā o methotrexate.
Hoʻohui ka koho me ka allopurinol hoʻonui i ka ulu ʻana o ka exanthema. ʻO ka hoʻohana pono ʻana me ka disulfiram e hōʻalo.
Hoʻemi i ka hopena o nā lāʻau lapaʻau, i ka wā o ka hana o ka metabolism i hana ai ʻo PABA, ethinyl estradiol - ka loaʻa aʻe o ke kahe pohō.
Hōʻike ka puke puke i nā hihia lihua o ka hoʻonui ʻana i ka INR i nā mea maʻi me ka hoʻohana pū ʻana o acenocumarol a i ʻole warfarin a me amoxicillin. Inā kūpono, hoʻohana pinepine ʻia me nā anticoagulants, pono e kiaʻi pono ʻia ʻo PV a me INR i ka wā i kuhikuhi ai a i ʻole ke hoʻopau i ka lāʻau.
ʻO ka hui pū me ka rifampicin he antagonistic (palupalu palupalu o ka hopena antibacterial). ʻAʻole pono e hoʻohana ʻo Amoxiclav ® i ka manawa like me ka hui pū me nā antibiotika bacteriostatic (macrolides, tetracyclines), sulfonamides ma kahi o kahi hiki ke emi i ka hopena o Amoxiclav ®.
Hoʻopiliʻo Amoxiclav ® i ka hopena o nā mea hoʻohālikelike waha.
No ka papa aku i nā papa ʻaila a me nā pauka no ka hoʻopanee ʻana i ka hoʻoponopono waha
Hoʻonui i ka hopena o ka anticoagulants kūpaʻa (ke kāohi ʻana i ka microflora pono o ka ʻōpū, hōʻemi i ka hoʻāla ʻana o ka vitamina K a me ka ʻōlelo prothrombin). I kekahi mau hihia, lawe i ka lāʻau lapaʻau e hiki ke hoʻonui i ka PV, ma kēia hana, pono e mālama ʻia i ka wā e hoʻohana ana i ka anticoagulants a me ka lāʻau lapaʻau Amoxiclav ® Quicktab.
Hoʻopala ka Probenecid i ka hoʻonuiʻana i ka amoxicillin, e hoʻonui ana i kona koʻikoʻi serum.
I ka poʻe maʻi e loaʻa ana i ka mycophenolate mofetil, ma hope o ka hoʻomaka ʻana o ka hoʻohana ʻana o ka hui o ʻoxxillillin me ka clavulanic acid, kahi hōʻemi i ka ʻike ʻana o ka metabolite ikaika, ka waika mycophenolic, ua nānā ʻia ma mua o ka lawe ʻana i ka hā aʻe o ka lāʻau i ka aneane 50%. ʻAʻole hiki ke loli maoli nā loli i loko o kēia neʻe i nā loli maʻamau i ka hōʻike ʻana o ka waikiko mycophenolic.
No ka pauku no ka hoʻomākaukau o kahi hopena no ka mālama ʻo iv
ʻO Amoxiclav® a me nā antibiotics aminoglycoside i kūleʻa hoʻohālikelike.
Mai hoʻohui iā Amoxiclav ® i kahi syringe a i ʻole infusion vial me nā lāʻau ʻē aʻe.
Hōʻalo i ka hoʻohui ʻana me nā mea hoʻonā o nā dextrose, dextran, sodium bicarbonate, a me ka hoʻonā ʻana i nā koko, nā protein, nā lipids.
ʻLoe a me ke kākele
Nā papa hana ʻulaʻī
I loko. Hoʻonohonoho ʻia ka nui o ka dosage ma ke ʻano, he pili i ka makahiki, ke kino o ke kino, ke ʻano o ka hana o ka mea maʻi, a me ka nui o ka maʻi.
Hoʻomaopopo ʻia ʻo Amoxiclav ® e lawe i ka hoʻomaka ʻana o ka ʻai no ka maikaʻi o ke komo ʻana a hiki i ka hoʻēmi ʻana i nā hopena hopena mai ka kūnaʻi ʻana.
ʻO ke ala e mālama ai i nā lā 5-14. Hoʻoholo ʻia ka lōʻihi o ke ʻano o ka mālama ʻana e ke kauka hele mai. ʻAʻole pono e hānai ʻia ʻoi aku ma mua o 14 mau lā inā ʻaʻole e hoʻopaʻa loiloi i ka lua.
E kau ʻia ka ʻōhua ma muli o ke ʻano a me ke kaumaha o ke kino. ʻO ka regimen dosis papa ʻia ʻo 40 mg / kg / lā ma 3 mau māhele i hoʻokaʻawale.
ʻO nā keiki me ka paona o ke kino he 40 kg a ʻoi aku paha e hāʻawi ʻia i nā pā kau like i nā pākeke. No nā keiki i ≤6 mau makahiki, ʻoi aku ka maikaʻi o ka lawe ʻana mai iā Amoxiclav ®.
ʻO nā pākeke a me nā keiki ma mua o 12 mau makahiki (a> 40 kg o ke kino kino)
ʻO ka maʻi maʻamau ma ka hihia o ka maʻi maʻamau a hōʻemi ʻia nā papa ʻaina. 250 + 125 mg i kēlā me kēia 8 mau hola a i ʻole 1 papa papaʻa. 500 + 125 mg i kēlā me kēia mau hola 12, ma ke ʻano o nā maʻi koʻikoʻi a me nā maʻi i ka hanu - 1 papa. 500 + 125 mg i kēlā me kēia 8 mau hola a i ʻole 1 papa papaʻa. 875 + 125 mg i kēlā me kēia 12 hola
Mai ka hui pū ʻana o nā papa ʻo amoxicillin a me clavulanic acid 250 + 125 mg a me 500 + 125 mg kēlā me kēia ka nui o ka clavulanic acid - 125 mg, a laila 2 mau papa. ʻO 250 + 125 mg ʻaʻole like ia me 1 papa. 500 + 125 mg.
ʻO nā heluʻai no nā maʻi odontogenic
1 kōpō. 250 + 125 mg i kēlā me kēia 8 mau hola a i ʻole 1 papa papaʻa. 500 + 125 mg i kēlā me kēia mau hola 12 no 5 mau lā.
ʻO ka maʻi me ka hana renal impaired
Kuhi ʻia ka hoʻoponopono ʻana i ka dosis me ka nui loa o ke ʻano loiloi ʻo amoxicillin a lawe ʻia i nā waiwai Cl Clininine:
- nā ʻōpio a me nā keiki i ʻoi aku ma mua o 12 mau makahiki (a i ʻole ≥40 kg paha o ke kaumaha o ke kino) (pakuhi 2),
- me anuria, ka nui ma waena o nā kikoiki e hoʻonui ʻia i 48 mau hola a keu paha.
Hoʻohana pono ʻia - 875 + 125 mg papa i nā maʻi me nā mea Cl Clin> 30 ml / min.
| Hoʻolaha ʻo Creinine | Ka lula ʻaʻoma Amoxiclav ® |
| > 30 ml / min | ʻAʻole koi ke hoʻoponopono ʻia |
| 10-30 ml / min | 1 kōpō. 50 + 125 mg 2 mau manawa i kahi lā a i ʻole 1 papa. 250 + 125 mg (me ka maʻi maʻalahi o ka maʻi mau) 2 mau manawa i kahi lā |
| E hoʻokō ʻia ka hana me ka akahele. Pono ke nānā pono ʻana i nā hana ate. |
ʻO ka pauka no ka pohō o ka waha
ʻO nā lā hoʻomaha o kēlā me kēia lā he 125 + 31.25 mg / 5 ml a me 250 + 62.5 mg / 5 ml (e hoʻomālamalama i ka dose kūpono, i kēlā me kēia pākeke o nā pona 125 + 31.25 mg / 5 ml a me 250 + 62.5 mg / 5 ml, kahi pipeta puka mua o 5 ml me kahi mālau he 0.1 ml a i ʻole ka pā kīpē 5-ml me nā hōʻailona annular i ka ana o 2.5 a me 5 ml).
ʻO nā keiki a me nā keiki a hiki i 3 mau mahina - 30 mg / kg / lā (e like me ke amoxicillin), i māhele ʻia i 2 mau pona (ʻo kēlā me kēia mau hola 12).
ʻO ka make ʻana o ka lāʻau Amoxiclav ® me kahi pipette dosing - ke helu helu ʻana i nā wai kū hoʻokahi no ka mālama ʻana i nā maʻi i nā keiki hou a me nā keiki a hiki i 3 mau mahina (Pihi 3).
| Kau ka paona | 2 | 2,2 | 2,4 | 2,6 | 2,8 | 3 | 3,2 | 3,4 | 3,6 | 3,8 | 4 | 4,2 | 4,4 | 4,6 | 4.8 |
| Hoʻopaʻa 156.25 ml (mau manawa 2 i ka lā) | 1,2 | 1,3 | 1,4 | 1,6 | 1,7 | 1,8 | 1,9 | 2 | 2,2 | 2,3 | 2,4 | 2,5 | 2,6 | 2,8 | 2,9 |
| Hoʻopaʻa 312.5 ml (2 mau manawa i ka lā) | 0,6 | 0,7 | 0,7 | 0,8 | 0,8 | 0,9 | 1 | 1 | 1,1 | 1,1 | 1,2 | 1,3 | 1,3 | 1,4 | 1,4 |
ʻOi aku nā keiki ma mua o 3 mau mahina - mai 20 mg / kg no ka maʻi o ka hōʻemi i ka hōʻemi a i ka hoʻohaʻahaʻa i ka 40 mg / kg no nā maʻi koʻikoʻi a me nā maʻi o ka hanu haʻahaʻa, otitis media, sinusitis (amoxicillin) i kēlā me kēia lā, i hoʻokaʻawale ʻia i 3 mau pona (i kēlā me 8 mau hola).
Ka make ʻana o ka lāʻau Amoxiclav ® me ka pipette dosing - ke helu helu ʻana i nā wai kū hoʻokahi no ka mālama ʻana i nā maʻi haʻahaʻa a me ke ʻano i nā keiki ʻoi aku ka 3 mau mahina (e pili ana i 20 mg / kg / lā (no ka amoxicillin) (Papa 4).
| Kau ka paona | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 |
| Hoʻopaʻa 156.25 ml (3 mau lā i ka lā) | 1,3 | 1,6 | 1,9 | 2,1 | 2,4 | 2,7 | 2,9 | 3,2 | 3,5 | 3,7 | 4 | 4,3 | 4,5 | 4,8 | 5,1 | 5,3 | 5,6 | 5,9 |
| Hoʻopaʻa 312.5 ml (3 mau manawa i ka lā) | 0,7 | 0,8 | 0,9 | 1,1 | 1,2 | 1,3 | 1,5 | 1,6 | 1,7 | 1,9 | 2 | 2,1 | 2,3 | 2,4 | 2,5 | 2,7 | 2,8 | 2,9 |
| Kau ka paona | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | |
| Hoʻopaʻa 156.25 ml (3 mau lā i ka lā) | 6,1 | 6,4 | 6,7 | 6,9 | 7,2 | 7,5 | 7,7 | 8 | 8,3 | 8,5 | 8,8 | 9,1 | 9,3 | 9,6 | 9,9 | 10,1 | 10,4 | |
| Hoʻopaʻa 312.5 ml (3 mau manawa i ka lā) | 3,1 | 3,2 | 3,3 | 3,5 | 3,6 | 3,7 | 3,9 | 4 | 4,1 | 4,3 | 4,4 | 4,5 | 4,7 | 4,8 | 4,9 | 5,1 | 5,2 |
Ka make ʻana o ka lāʻau Amoxiclav ® me ka pipette dosing - ke kau helu ʻana i nā helu kū hoʻokahi no ka mālama ʻana i nā maʻi ʻino loa i nā keiki ʻoi aku ka 3 mau mahina (e pili ana i ka 40 mg / kg / lā (no ka amoxicillin) (Papa 5).
| Kau ka paona | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 |
| Hoʻopaʻa 156.25 ml (3 mau lā i ka lā) | 2,7 | 3,2 | 3,7 | 4,3 | 4,8 | 5,3 | 5,9 | 6,4 | 6,9 | 7,5 | 8 | 8,5 | 9,1 | 9,6 | 10,1 | 10,7 | 11,2 | 11,7 |
| Hoʻopaʻa 312.5 ml (3 mau manawa i ka lā) | 1,3 | 1,6 | 1,9 | 2,1 | 2,4 | 2,7 | 2,9 | 3,2 | 3,5 | 3,7 | 4 | 4,3 | 4,5 | 4,8 | 5,1 | 5,3 | 5,6 | 5,9 |
| Kau ka paona | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | |
| Hoʻopaʻa 156.25 ml (3 mau lā i ka lā) | 12,3 | 12,8 | 13,3 | 13,9 | 14,4 | 14,9 | 15,5 | 16 | 16,5 | 17,1 | 17,6 | 18,1 | 18,7 | 19,2 | 19,7 | 20,3 | 20,8 | |
| Hoʻopaʻa 312.5 ml (3 mau manawa i ka lā) | 6,1 | 6,4 | 6,7 | 6,9 | 7,2 | 7,5 | 7,7 | 8 | 8,3 | 8,5 | 8,8 | 9,1 | 9,3 | 9,6 | 9,9 | 10,1 | 10,4 |
Ka make ʻana o ka lāʻau Amoxiclav ® me kahi wai dosage (i ka ʻike ʻole ʻana o ka pipette dosage) - ke ʻano o ka ʻōkuhi i hāpai ʻia e kau ana ma muli o ke kaumaha o ke keiki a me ka uha o ka maʻi (Papa 6).
| Kau ka paona | Nā ʻōpio (kahi kokoke) | ʻ courselelo haʻahaʻa / moderate | Kūʻai koʻikoʻi | ||
| 125 + 31.25 mg / 5 ml | 250 + 62.5 mg / 5 ml | 125 + 31.25 mg / 5 ml | 250 + 62.5 mg / 5 ml | ||
| 5–10 | 3-12 mahina | 3 × 2,5 ml (½ punela) | 3 × 1.25 ml | 3 × 3.75 ml | 3 × 2 ml |
| 10–12 | 1-2 mau makahiki | 3 × 3.75 ml | 3 × 2 ml | 3 × 6.25 ml | 3 × 3 ml |
| 12–15 | 2–4 makahiki | 3 × 5 ml (1 kele) | 3 × 2,5 ml (½ punela) | 3 × 7.5 ml (1½ punetēl) | 3 × 3.75 ml |
| 15–20 | 4-6 makahiki makahiki | 3 × 6.25 ml | 3 × 3 ml | 3 × 9.5 ml | 3 × 5 ml (1 kele) |
| 20–30 | 6-10 mau makahiki | 3 × 8.75 ml | 3 × 4.5 ml | - | 3 × 7 ml |
| 30–40 | 10-12 mau makahiki | - | 3 × 6.5 ml | - | 3 × 9.5 ml |
| ≥40 | ʻ≥12 mau makahiki | Nā papa kekona Amoxiclav ® | |||
ʻO kēlā me kēia lā no ka hoʻokuʻuʻana i ka 400 mg + 57 mg / 5 ml
Hoʻomoe ʻia ka makeʻana i ka kg o ke kaumaha o ke kino, ma muli o ka nui o ka maʻi. Mai 25 mg / kg no ka maʻi o ka hōʻoluʻolu a i ke hōʻemi ʻana i ka hōʻemi a i ka 45 mg / kg no nā maʻi koʻikoʻi a me nā haʻahaʻa o ka hanu haʻahaʻa, otitis media, sinusitis (ma nā ʻōlelo o ka amoxicillin) i kēlā me kēia lā, i hoʻokaʻawale ʻia i 2 mau maʻi.
No ka hoʻomaʻamaʻa i nā dosa kūpono, ua kau ʻia kahi pēpē he 400 mg + 57 mg / 5 ml i kēlā me kēia paena o ka pipette dosage, hoʻopau ʻia i ka manawa like i ka 1, 2, 3, 4, 5 ml a me nā māhele like 4.
Hoʻohana ʻia ka hoʻokuʻu ʻia o 400 mg + 57 mg / 5 ml i nā keiki i ʻoi aku o 3 mau mahina.
ʻO ke ʻano kūpono o ka pohō ʻana ma muli o ke kino o ke keiki a me ka nui o ka maʻi
| Kau ka paona | Nā ʻōpio (kahi kokoke) | Hana ʻia kā Damu, ml | |
| Kūʻai koʻikoʻi | Papa papa | ||
| 5–10 | 3-12 mahina | 2×2,5 | 2×1,25 |
| 10–15 | 1-2 mau makahiki | 2×3,75 | 2×2,5 |
| 15–20 | 2–4 makahiki | 2×5 | 2×3,75 |
| 20–30 | 4 makahiki - 6 mau makahiki | 2×7,5 | 2×5 |
| 30–40 | 6-10 mau makahiki | 2×10 | 2×6,5 |
Hoʻoholo ʻia nā dole kūpono i kēlā me kēia lā ma ke paona o ke keiki, a ʻaʻole ʻo kona makahiki.
ʻO ka nui loa o ka lā ma amoxicillin o 6 g no nā pākeke a 45 mg / kg no nā keiki.
ʻO ka nui loa o ka lā no clavulanic acid (ma ke ʻano o ka paʻakai pākela) ʻo 600 mg no nā pākeke a me 10 mg / kg no nā keiki.
I ka poʻe maʻi me ka hana renal impaired, pono ke hoʻoponopono ʻia e kau ʻia ma muli o ka nui o ka nui o ka dosis nui o ka amoxicillin.
ʻO nā mea maʻi me ka creatinine Cl> 30 ml / min, ʻaʻole ia e hoʻoponopono i kekahi lāʻau hoʻoponopono.
ʻO nā pākeke a me nā keiki ke kaupaona ʻana ma mua o 40 kg (ʻo ka nui o ka regimen e hōʻike ʻia nei no ka maʻi ʻana o ka papa e hōʻemi a me ka pilikia)
ʻO nā mea maʻi me ka Cl creatinine 10-30 ml / min - 500/125 mg 2 mau manawa i kahi lā.
I ka manawa iā Cl creatinine Cl creatinine 10-30 ml / min, ʻo ke kauoha i hōʻike ʻia he 15 / 3.75 mg / kg 2 mau manawa i ka lā (kiʻekiʻe 500/500 mg 2 mau manawa i ka lā).
Me Cl Clinine iv
Nā Keiki: me ke kaumaha o ke kino e emi iho ma lalo o 40 kg - ua kauʻia ke ʻano ma muli o ke kaumaha o ke kino.
ʻOi aku ma mua o 3 mau mahina me ke kaumaha o ke kino ma mua o 4 kg - 30 mg / kg (ma nā hua o ka lāʻau Amoxiclav ® a pau) i kēlā me kēia mau hola 12
Ma lalo o 3 mau mahina me ke kino o ke kino ma mua o 4 kg - 30 mg / kg (ma nā hua o ka lāʻau Amoxiclav ® a pau) i kēlā me kēia 8 mau hola
I nā keiki i ʻoi aku ma mua o 3 mau mahina, e lawelawe ʻia ʻo Amoxiclav ® i ka infusion lohi wale nō ma kahi o 30-40 mau minuke.
Na keiki mai 3 mau mahina a hiki i 12 mau makahiki - 30 mg / kg (ma nā ʻōlelo o ka mākaukau piha ʻo Amoxiclav ®) me kahi manawa o 8 mau hola, inā he maʻi koʻikoʻi - me kahi 6 o hola
ʻO nā keiki me ka hana pūlea pale ʻole
Kuhi ʻia ka hoʻoponopono ʻana i ka dosis ma ka nui o ke ʻano loiloi ʻo amoxicillin. No nā mea maʻi me Cl creatinine ma luna o 30 ml / min, ʻaʻole pono ka hoʻoponopono ʻana o ka maʻa.
Ke kaupaona nei nā keiki iā Cl creatinine 10-30 ml / min
ʻO nā pākeke a me nā keiki he 12 a keu paha ke kaupaona ʻana ma mua o 40 kg - 1,2 g o ka lāʻau lapaʻau (1000 + 200 mg) me kahi manawa o 8 mau hola, ma ke ʻano o kahi hopena koʻikoʻi - me kahi 6 o nā hola.
Nā kānana kūpono no ka pale ʻana o ka hōʻemi: 1.2 g me ka hoʻoluhi o ka anesthesia (me ka ʻoi ʻana o ka wā o ka hōʻemi ma mua o 2 mau hola). No nā hana lōʻihi - 1.2 g a 4 mau manawa i ka lā.
No nā mea maʻi me ka pūpū māmā, pono ke hoʻoponopono ʻia i ka nui o ka hopena a me / a i waena o nā inikua o ka lāʻau e pili ana i ke ʻano o ka lawa ʻole.
| Cl hana | Ka hana a / a waena paha o nā luna |
| > 0,5 ml / s (30 ml / min) | ʻAʻole koi ke hoʻoponopono ʻia |
| 0.166-00 ml / s (10-30 ml / min) | ʻO ka hapa mua loa he 1,2 g (1000 + 200 mg), a laila 600 mg (500 + 100 mg) iv i kēlā me kēia mau hola 12 |
| iv kēlā me 24 hola | |
| Anuria | Pono e hoʻonui ʻia ke koena kia 48 mau hola a keu paha. |
No ka mea, ua wehe ʻia ka 85% o ka lāʻau e ka hemodialysis, ma ka hope o kēlā me kēia kaʻina hemodialysis, pono ʻoe e komo i ka maʻi maʻamau o Amoxiclav ®. Me ka dialysis peritoneal, ʻaʻole pono ka hoʻoponopono ʻana.
ʻO ke ala e mālama ai i nā lā 5-14. Hoʻoholo ʻia ka lōʻihi o ke ʻano o ka mālama ʻana e ke kauka hele mai. Me ka hoʻohaʻahaʻa ʻana i ka uha o nā hōʻailona, ua neʻe ka hoʻololi i nā ʻano waha o Amoxiclav ® e hoʻomau i ka maʻi.
ʻO ka hoʻomākaukau ʻana i nā hoʻonā no ka maʻi injection. Hoʻomoe i nā ʻike o ke kīʻaha i loko o ka wai no ka hiki ʻana: 600 mg (500 + 100 mg) i 10 ml o ka wai no ka maʻi a i ʻole 1.2 g (1000 + 200 mg) i 20 ml o ka wai no ka maʻi. I loko / i mea e ulu mālie (i loko o 3-4 mau minuke).
E lawelawe ʻia ʻo Amoxiclav ® i loko o 20 mau minuke ma hope o ka hoʻomākaukau ʻana o nā mea hoʻonā no ka hoʻokele iv.
ʻO ka hoʻomākaukau ʻana i nā hoʻonā no ka infusion iv. No ka hoʻopiʻi infusion o Amoxiclav ®, pono e hoʻopili hou ʻia: nā hāmeʻa i hoʻomākaukau ʻia e loaʻa ana iā 600 mg (500 + 100 mg) a i 1,2 g (1000 + 200 mg) o ka lāʻau e hoʻemi ʻia i loko o 50 a 100 ml o ka hopena o ka infusion, ia. ʻO ka lōʻihi o ka infusion he 30-40 mau minuke.
Ke hoʻohana nei i nā waiila e hiki mai ana i loko o nā poloka i manaʻo ʻia i nā hoʻonā infusion, e mālama ʻia nā mea e pono ai ka antibiotic:
| Nā wai hou i hoʻohana | Pahu Hooko, h | |
| i 25 ° C | i 5 ° C | |
| Ka wai no ka ʻaina | 4 | 8 |
| ʻO 0.9% paʻakai sodium klorida no iv infusion | 4 | 8 |
| Hoʻolaha ka hopena o Ringer no ka lactate no ka iv infusion | 3 | |
| ʻO ka hopena o ka calcium chloride a me ka sodium klorida no iv infusion | 3 | |
ʻAʻole hiki ke hui pū ʻia ka hopena o ka lāʻau Amoxiclav ® me nā hopena o ka dextrose, dextran a i ʻole sodium bicarbonate.
E hoʻohana wale i nā mea hoʻonā maʻalahi. ʻAʻole ʻōlaʻa nā hoʻoponopono i hoʻomākaukau ʻia.
I loko. Hoʻonohonoho ka dosage dosage i kū hoʻokahi i ka makahiki, ke kino, ke ʻano hana a ka mea maʻi a me ka nui o ka maʻi.
Pono e hoʻokaʻawale ʻia nā papa i ka hapalua o ke aniani o ka wai (ma kahi o 30 ml) a kāwili i ka maoli, a laila inu a paʻa paha i nā papa i loko o ka waha a pau a hoʻomalo wale ʻia, a laila puhi.
I mea e hōʻemi ai i ka hopena o nā hopena ʻaoʻao mai ka gastrointestinal tract, pono ke lawe ʻia ka lāʻau i ka hoʻomaka o ka ʻai.
Amoxiclav ® Nā Kūwila Kūʻai Kūʻai Kūʻai 500 mg / 125 mg:
ʻO nā pākeke a me nā keiki ma mua o 12 mau makahiki me ke kaumaha o ke kino ≥40 kg
No ka mālamaʻana i ka hopena o ka maʻi o ka palalelo i ke ʻano paʻakikī - 1 papa. (500 mg / 125 mg) i kēlā me kēia mau hola 12 (2 mau manawa i kahi lā).
No ka mālamaʻana i nā maʻi weliweli a me nā maʻi o ka ʻoihana hanu - 1 papa. (500 mg / 125 mg) kēlā me kēia mau hola 8 (3 mau manawa i ka lā).
ʻO ka palena loa o kēlā me kēia lā o Amoxiclav ® Quicktab he 1,500 mg o ka amoxicillin / 375 mg o ka clavulanic acid.
ʻO ka maʻi me ka hana renal impaired. I nā maʻi me ka creatinine Cl ma mua o 30 ml / min, ʻaʻole pono ka hoʻoponopono ʻana o ka maʻa.
ʻO nā ʻōpio a me nā keiki ʻoi aku ma mua o 12 mau makahiki me ke kaumaha o ke kino ≥40 kg (ʻo ka regimen hōʻailona i hōʻike ʻia no ka maʻi ʻana o ke ʻano maʻalahi a me ke kaumaha):
| Cl Mea hana, ml / min | Dosis |
| 10–30 | 500 mg / 125 mg 2 mau manawa i ka lā (me ka maʻi maʻalahi i ka maʻi koʻikoʻi) |
| ® Loaa 875 mg / 125 mg: |
ʻO nā pākeke a me nā keiki ma mua o 12 mau makahiki me ke kaumaha o ke kino ≥40 kg
I nā maʻi koʻikoʻi a me nā hopena i ka hanu - 1 papa. (875 mg / 125 mg) kēlā me kēia mau hola 12 (2 mau manawa i kahi lā).
ʻO ka lā helu o kēlā me kēia lā ka lāʻau ʻo Amoxiclav ® Quicktab i ka wā hoʻohana ʻia 2 mau manawa i ka lā he 1750 mg o ka amoxicillin / 250 mg o ka clavulanic acid.
ʻO ka maʻi me ka hana renal impaired. I nā mea maʻi me Cl creatinine ʻoi aku ka nui ma mua o 30 ml / min, ʻaʻohe mea pono o ka hoʻoponopono hoʻoponopono lāʻau.
No ka mea maʻi me Cl creatine ma lalo o 30 ml / min, ke hoʻohana ʻana i nā papa pālahalaha o ka lāʻau ʻAmoxiclav ® Quicktab, 875 mg / 125 mg, ua contraindicated.
Pono ka mea maʻi e lawe i ka lāʻau lapaʻau ma ke kaoa o 500 mg / 125 mg ma hope o ka hoʻoponopono ʻana o ka hoʻoponopono kūpono o ka creatinine Cl.
ʻO nā maʻi me ka hana pūlima hemahema. Ke lawe aku iā Amoxiclav ® Quicktab, pono e hoʻomaʻamaʻa. Pono ke nānā pono ʻana i nā hana ate. Ma ka hanana e hoʻomaka ʻia ka mālama ʻana me ka hoʻokele makua o ka lāʻau lapaʻau, hiki iā ia ke hoʻomau i ka maʻi me nā papa o Amoxiclav ® Quicktab.
Hoʻoholo ʻia ka lōʻihi o ke ala o ka mālama ʻia e ke kauka hele mai!
ʻO ka papa haʻahaʻa o nā mea maʻi maʻiʻo 5 mau lā. ʻAʻole pono e hoʻomau ka hoʻomehana no nā lā 14 me ka ʻole o ka loiloi o ke kūlana haukapila.
Ke keu
ʻAʻohe mau hōʻike e pili ana i ka make a i ke ola e pili ana i ka hopena ma muli o ka make nui o ka lāʻau.
Nā Hoʻomaka i nā manawa maʻamau, nā pilikia o ka haki o ka gastrointestinal (hōʻeha o ka ʻōpū, ka ʻōpū, ka luaʻi)
Lāʻau: ma kahi o kahi overdose, pono i ka mea maʻi ma lalo o ka mālama o kekahi kauka, he hōʻailona lāʻau.
Ma ka hihia o kahi hoʻokele hou loa (ʻoi aku ka 4 mau hola) o ka lāʻau lapaʻau, pono ia e holoi i ka ʻōpū a hoʻonā i nā ulana i hoʻolaʻa ʻia e hōʻemi i ke kōpili. Hoʻokuʻuʻia ka amoxicillin / potassium clavulanate e ka hemodialysis.
Nā ʻōlelo kikoʻī
No nā palapala hoʻoponopono āpau
Me kahi papa hana o ka mālama ʻana, pono ia e nānā i ke ʻano o ka hana o ke koko, a me nā ʻōpio, a me nā puʻukū.
I nā maʻi me nā maʻi hānai koʻikoʻi, kūpono kahi hoʻoponopono hoʻoponopono a i ʻole ka nui o nā kikowaena ma waena o nā wīwī.
Hiki ke hoʻomohala i ka superinfection ma muli o ka ulu o ka microflora insensitive iā ia, pono e koi i ka loli like me ka lāʻau antibiotic.
I nā mea maʻi me ka hypersensitivity i ka penicillins, hiki i nā hopena cross-allergic me nā cephalosporin antibiotics.
I nā wahine me ka wā wehe mua o nā membrane, ua ʻike ʻia ka pili ʻana o ka prophylactic therapy me ka amoxicillin + clavulanic acid me ka nui o ka pilikia o ka necrotizing colitis i nā keiki hou.
I nā maʻi me ka diuresis ho'ēmi, crystalluria kahi ʻemi nui loa. I ka wā o ka hoʻohana nui ʻana o nā dosis nui o ka amoxicillin, ua manaʻo ʻia e lawe i ka nui o ka wai me ka mālama i ka diuresis kūpono e hōʻemi ai i ka hopena o ka hoʻokumu ʻana o nā crystals amoxicillin.
Nā hōʻike hōʻike Laboratory. Hāʻawi nā mea koʻikoʻi o ka amoxicillin i kahi hopena hoʻopunipuni a maikaʻi i ka glucose i ka urine i ka wā e hoʻohana ai i ka hoʻoulu hou ʻana o Benedict a i ʻole ka hopena a Feling. Hoʻomaopopo ʻia nā ʻano hopena Enzymatic me ka glucosidase.
No ka papa aku i nā papa ʻaila a me nā pauka no ka hoʻopanee ʻana i ka hoʻoponopono waha
Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, pono e ninaninau i ka mea maʻi e maopopo i ka mōʻaukala o nā hopena hypersensitivity i ka penicillins, cephalosporins, a i ʻole nā hopena beta-lactam aʻole.
I mea e hōʻemi ai i ka hopena o nā hopena ʻaoʻao mai ka gastrointestinal tract, pono pono e lawe ʻia ka lāʻau lapaʻau ma mua o i ka wā o ka pāʻina.
Ke hoʻohana nui nei i nā wai kiʻekiʻe o Amoxiclav ® Quiktab, pono nā mea maʻi me ka crystalluria e hoʻopiha piha i ka kahe wai.
Inā hele mai nā colitis e pili ana i ka antibiotika, e kāpae koke iā Amoxiclav ® Quicktab, e nīnau aku i kahi kauka a hoʻomaka i ka mālama kūpono. ʻO nā lāʻau lapaʻau e pale i ka peristalsis e hoʻohālikelike i nā kūlana.
Ke hoʻomau nei ka lāʻau no nā hola 48-75 ma hope o ka nalo ʻana o nā hōʻailona lapaʻau o ka maʻi. Me ka hana like o ka manuahi estrogen e loaʻa ai ka waha a me ka amoxicillin, nā hana a me nā mea hou aku paha e hoʻohana ai inā hiki.
ʻO Amoxicillin a me clavulanic acid ka mea e hoʻonāukiuki i ka nakona nonspecific o ka immunoglobulins a me ka albumin i ka membrane erythrocyte, hiki iā ia ke kumu o ka hopena maikaʻi ʻole ma ke hōʻike ʻo Coombs.
Hoʻohana ʻia ka hoʻohana ʻana o ka amoxicillin a me ka acid clavulanic i loko o ka mononucleosis infectious, no ka mea paha e hoʻonāukiuki i ke ʻano o kahi wikiwiki.
Pākuʻi kūikawā no ka hoʻokuʻu ʻana i nā lāʻau lapaʻau hoʻohana ʻole ʻia. ʻAʻohe mea pono no ka mālama mua ʻana i ka wā a pau ʻole i ka hoʻohana ʻole ʻia ʻo Amoxiclav ®.
Ka hopena i ka hiki ke alakaʻi i kahi kaʻa a hana paha i nā hana e pono ai ka hoʻonui ʻana i ke ʻano o ke kino a me ka noʻonoʻo. Ma muli o ka hiki ke hoʻomohala ʻana i nā hopena ʻaoʻao mai ka pūnaehana neʻe, ʻo ka maʻi, ke poʻo, a me ka hoʻokau ʻana, pono e hoʻomaʻamaʻa ʻia i ka wā o ka mālama ʻana i ka wā e alakaʻi ai a me nā hana ʻē aʻe e koi ai i ka neʻe ʻana a me ka wikiwiki o ka hopena psychomotor.
No nā papa kiʻi ʻoniʻoni, papa nāu, hoʻōla no ka hoʻokuʻu ʻana i ka waha, ʻoi aʻe
I mea e hōʻemi ai i ka hopena o nā hopena ʻaoʻao mai ka gastrointestinal tract, pono ke lawe ʻia ka lāʻau lapaʻau me ka ʻai.
No ka pauku no ka hoʻomākaukau o kahi hopena no ka mālama ʻo iv
Hiki i ka Amoxicillin a me clavulanic acid ke hoʻonāukiuki i ka hoʻopono nonspecific o ka immunoglobulins a me ka albumin i ka membrane erythrocyte, hiki iā ia ke kumu o kahi hōʻike Coombs maikaʻi maikaʻi.
ʻO ka ʻikepili no nā poʻe maʻi ma ka liʻiliʻi ʻoi sodium: kēlā me kēia 600 mg vial (500 + 100 mg) loaʻa i ka 29.7 mg o ka sodium. ʻO kēlā me kēia kīʻaha o 1,2 g (1000 + 200 mg) kahi 59.3 mg o ka sodium. ʻO ka nui o ka sodium ma ka laʻana o kēlā me kēia lā ma mua o 200 mg.
E hoʻokuʻu i ke ʻano
Nā papa hana ʻaniʻoni kiʻi, 250 mg + 125 mg. 15, 20 a i ʻole 21 papa papaʻa. a me 2 desiccants (silica gel) i loko o kahi pahu i ulaula wili me ka huaʻōlelo "inedible" i loko o kahi pahu aniani i hoʻopuni ʻia me ka pōpoki metala me ke kaomi mana me ka perforation a me kahi gasket LDPE i loko. 1 fl. i kahi kāwili kāleka.
ʻO nā papa ʻōlelo ʻaniʻoni kiʻi, 500 mg + 125 mg. 15 a 21 paha papa. a me 2 desiccants (silica gel) i loko o kahi pahu i ulaula wili me ka huaʻōlelo "inedible" i loko o kahi pahu aniani i hoʻopuni ʻia me ka pōpoki metala me ke kaomi mana me ka perforation a me kahi gasket LDPE i loko. 1 fl. i kahi kāwili kāleka.
A i ʻole 5 a me 7 mau papa. i kahi pākeka wīwī paʻakikī a i loaʻa ai kahi alumini alumini. 2, 3 a i ʻole 4 mau polō no nā papa 5. a i ʻole he 2 mau pōpō no nā papa 7. i kahi kāwili kāleka.
ʻO nā papa hoʻoili kiʻiʻoniʻoni, 875 mg + 125 mg. A i ʻole 5 a me 7 mau papa. i kahi pākeka wīwī paʻakikī a i loaʻa ai kahi alumini alumini. 2 a i ʻole 4 mau polō no ka 5 papa. a i ʻole he 2 mau pōpō no nā papa 7. i kahi kāwili kāleka.
Ka paena no ka hoʻokuʻu ʻana i ka waha, 125 mg + 31.25 mg / 5 ml a i ʻole 250 mg + 62.5 mg / 5 ml. ʻO ka pauku mua - 25 g o ka pauka (100 ml o ka pauku i hoʻopau ʻia) i loko o kahi kīʻahaʻeleʻeleʻeleʻele me kahi hōʻailona o ke apo (100 ml). Hoʻopili ʻia ka pahu momona e ka pāpale kila ma nā pale keleawe i loko o ke kahe pale, i loko o ka pāpale kahi kekahila i hana ʻia o LDPE.
Ke kope kūmole - 1 fl. me kahi pāʻina nui me nā hōʻailona makahiki i loko o ka lua o 2,5 a me 5 ml ("2.5 SS" a me "5 SS"), he hōʻailona o ka hoʻopiha piha ʻana o 6 ml ("6 SS") ma ke kau o ka puna ma kahi pahu pahu. A 1 paha fl. pū me ka pipette puka i ke kāwele pepa.
ʻO ka pauka no ka hoʻokuʻu ʻana i ka waha, 400 mg + 57 mg / 5 ml. Kūleʻa mua - 8.75 g (35 ml o ka hoʻōki paʻa), 12.50 g (50 ml o ka ʻauʻa ʻana i hoʻopau ʻia), 17,50 g (70 ml o ka hana hoʻokele paʻa) a i ʻole 35.0 g (140 ml o ka hoʻokuʻu 'ana) o ka pauka i loko o kahi vial aniani aniani me kahi uhi poʻohiwi paʻa i ka HDPE me ke kaomi mana a me kahi panana i loko o ka uhi.A i ʻole 17.5 g (70 ml o ka hoʻokō ʻana i hoʻopau ʻia) i loko o kahi kīʻaha pōkole me kahi hōʻailona hōʻailona (70 ml) me kahi pōpoki i hana ʻia o HDPE me ke kaomi mana a me kahi panana i loko o ka uhi.
Ke kope kūmole - 1 fl. pū me ka pipette puka i ke kāwele pepa.
ʻO ka pauka no ka hoʻonā ʻana no ka hoʻokele intravenous, 500 mg + 100 mg a i ʻole 1000 mg + 200 mg. ^ E Ha yM. 500 mg o ka amoxicillin a me 100 mg o ka clavulanic acid a i ʻole o 1000 mg o ka amoxicillin a me 200 mg o ka clavulanic acid i kahi kīʻaha kīʻaha ʻole, ua hoʻopiʻi ʻia me ka mea hana kīkoki a me kahi pōpō alumini pōpoki me kahi pāpale plastik. 5 fl. waiho ʻia i loko o kahi pahu pahu.
Nā papa ʻaila, 500 mg + 125 mg a i ʻole 875 mg + 125 mg. 2 papa i kahi pīhoihoi. Hoʻonoho ʻia a i ʻole nā pahu 5 a i ʻole ma kahi kāleka.
Mea hana
Lek dd Verovshkova 57, Ljubljana, Slovenia.
No ka pauku no ka hoʻomākaukau o ka hoʻonā no ka hoʻokele intravenous hou
1. Lek dd, Verovshkova 57, Ljubljana, Slovenia.
2. Sandoz GmbH, Biohemistrasse 10 A-6250, Kundl, Austria.
Pono e hoʻouna ʻia nā koi o nā mea kūʻai aku i Sandoz CJSC: 125317, Moscow, Presnenskaya nab., 8, p.
Tel .: (495) 660-75-09, fax: (495) 660-75-10.
Amoxiclav ®
nā papa kiʻi ʻoniʻoni 250 mg + 125 mg 250 mg + 125 - 2 mau makahiki.
nā pani ʻoniʻoni kiʻi 500 mg + 125 mg 500 mg + 125 - 2 mau makahiki.
nā papa kiʻi ʻoniʻoni 875 mg + 125 mg 875 mg + 125 - 2 mau makahiki.
pauku no ka hoʻomākaukau ʻana i kahi hopena no ka hoʻokō intravenous o 500 mg + 100 mg 500 mg + 100 - 2 mau makahiki.
pauku no ka hoʻomākaukau ʻana i kahi hopena no ka hoʻokō intravenous o 1000 mg + 200 mg 1000 mg + 200 - 2 mau makahiki.
nā papa pālahalaha 500 mg + 125 mg 500 mg + 125 - 3 mau makahiki.
papa pālaʻi 875 mg + 125 mg 875 mg + 125 - 3 mau makahiki.
hoʻomoʻa no ka hoʻokuʻuʻana no ka hoʻokūkū waha 125 mg + 31.25 mg / 5 ml 125 mg + 31.25 mg / 5 - 2 mau makahiki. ʻO ka pau aʻe o ka hoʻopau ʻia he 7 lā.
pauku no ka hoʻōki ʻana no ka hoʻokūkū waha 250 mg + 62.5 mg / 5 ml 250 mg + 62.5 mg / 5 - 2 mau makahiki. ʻO ka pau aʻe o ka hoʻopau ʻia he 7 lā.
pauku no ka hoʻōki ʻana no ka hoʻokūkū waha 400 mg + 57 mg / 5 ml 400 mg + 57 mg / 5 - 3 mau makahiki. ʻO ka pau aʻe o ka hoʻopau ʻia he 7 lā.
Mai hoʻohana ma hope o ka lā pau pau i hōʻike ʻia ma ka pahu.
Nā mea hoʻohālikelike a me nā huahana pharmacological o Amoxiclav 125 milligrams
ʻAihoki Amoxiclav 125 mg:
- ʻO Amoxicillin - e pili ana i nā penicillins i hiki ke hoʻoliʻi a hoʻopau i kekahi nui o nā microorganism o nā haole a me nā pōʻino.
- ʻO Clavulanic waikawa he beta-lactam, e hoʻohiolo ana i ka hala o ka mea nui a no laila e hoʻolōʻihi i ka manawa o ka hui penicillin.
ʻO ka hoʻokuʻu a me ka mana o ka lāʻau lapaʻau e ʻae i nā mea maʻi i nā kūlana e pili ana i ka hakakā ʻana i ka maʻi me ka noʻonoʻo ʻole i ka hōʻeha koʻikoʻi i ke kino. ʻO kahi nui o nā loea e ʻōlelo i ka lāʻau lapaʻau e like me kahi o ka maʻalahi o nā keiki a me nā pākeke e heluhelu.
ʻO nā ʻōkuhi no ka hoʻohana a me ke ʻano o ka hoʻokuʻu ʻana e wehewehe i nā papa Amoxiclav a me nā hana hoʻokiʻoki ʻo Amoxiclav (ʻoi aku ka nui, ka pauka no ka hoʻomākaukau no ka hoʻokuʻa).
ʻAʻohe! Aia ka hakuxiclav quiktab, eia naʻe, kūʻai ʻia, aia wale nō i kūʻai ʻia i nā waiwai 625 mg a me 1000 mg.
Me ka ʻike koʻikoʻi o nā mea ikaika, ʻo ia ka 5 ml o ka lāʻau = 125 mg o ka amoxicillin + 31.5 mg o ka clavulanic acid, e kōkua ana i ka hoʻokūkū i nā maʻi.
ʻO ka wehewehe ʻana o ka lāʻau lapaʻau e hōʻoia ana e make ana ka lāʻau lapaʻau i kekahi mau ʻano o nā palupalu a me nā microorganisms. 'Lelo pinepine lākou e pili ana ʻo Amoxiclav 125 i nā keiki, no ka mea, ma ka puka wai, e hoʻomaʻemaʻe i ka hoʻohana ʻana.
Pehea e ʻano ai
I mea e aʻo ai i ke lawe ʻana iā ia i nā keiki, a ʻo ka mea nui ka pehea e hoʻoheheʻe pololei ai ʻo amoxiclav, pono ʻoe e nānā i nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana.
- E lulu i ka pauku e waiho ʻia i kahi ʻāpana.
- E hoʻohui i ka hue o ka wai maʻemaʻe mua i ka waena o ka pahu a lulu, a laila e hoʻohui i ka nui o ka wai i ka hue, akā aia a hiki i ka hōʻailona ma ka pahu. Ma hope o kēia, e lūlū hou i ka haʻaleleʻana o Amoxiclav.
E hoʻaloʻaleʻa i ka lāʻau lapaʻau me 86 mau mililiter o ka wai, a me ka pau ʻana o nā hana hoʻōki no nā keiki i ka puka ākea he he pule.
ʻAʻohe! ʻO ke ʻano o ka hoʻomākaukau ʻana o ka ʻōmaka o Amoxiclav 125 mg i kahi keiki ʻelua makahiki ʻelua, ʻaʻole ia e ʻokoʻa i kahi ʻano mai ka hoʻomake ʻana o ka lāʻau lapaʻau no kahi keiki o 12 mau makahiki. He mea nui e hoʻohālikelike pono i ka ʻona no laila ka hopena o ka syrup.
Ehia mau mea e lawe
ʻO Amoxiclav e like me nā kauoha i lawe ʻia mai 5 a 7 mau lā, ʻoiai naʻe, e like me ka mea i kauoha ʻia e ke kauka, hiki iā ʻoe ke inu i ka lāʻau lapaʻau a hiki i ʻelua pule. ʻOi aku ma mua o 14 mau lā, ka lawe ʻana iā Amoxiclav 125 i kūpono ʻole ia, no ka hiki ke hoʻohana ʻia i ka lāʻau.
ʻO ka mea nui e hoʻomanaʻo ai ke lawe ʻana iā Amoxiclav 125 mg ʻo ia ka nui o nā lā e hoʻohana ai i ka lāʻau lapaʻau e pono e hoʻoholo e ke kauka hele mai. ʻO ka hōʻino ʻana i nā ʻōlelo o ka pediatrician hiki ke alakaʻi i nā hopena maikaʻi ʻole.
