Tsifran OD (Сifran OD)

Lapaʻau lāʻau Hoʻopili ʻia ʻo Ciprofloxacin i loko o vitro kahi pālahalaha nui o nā pakanā a me nā gram-maikaʻi nā microorganisms. ʻO ka hana bactericidal o ciprofloxacin ka hopena o ka keʻa ʻana o ka enzymes topoisomerase II (DNA gyrase) a me topoisomerase IV, e pono ai no ka hoʻohālike, transcription, hoʻoponopono hou a me ka hana hou ʻana o ka DNA bacterial. ʻO ka hana o ka hana o ka fluoroquinolones, me nā ciprofloxacin, ʻokoʻa aku i ka hana o ka hana o nā penicillins, cephalosporins, aminoglycosides, macrolides a tetracyclines. No laila, hiki i nā microorganism ke kū i kēia mau papa o nā lāʻau lapaʻau e nānā i ka ciprofloxacin a me nā quinolones. ʻAʻohe mea i ʻike ʻia-pale ma waena o ciprofloxacin a me nā papa ʻē aʻe o nā lāʻau antibacterial. Kākoʻo i loko o vitro e ulu mālie a ciprofloxacin. Hoʻomaʻamaʻa ʻo Ciprofloxacin i ka hapanui o nā kaha o nā microorganism e like me kēia i loko o vitroi nā maʻi lapaʻau,
aerobic gram-microorganisms maikaʻi: Enterococcus faecalis (he mau mānoina nui ka hanu), Staphylococcus aureus (MSSA), Staphylococcus epidermidis (MSSA), Staphylococcus saprophyticus, Streptococcus pneumoniae (PSSP), Streptococcus pyogenes,
aerobic gram-microorganisms maikaʻi: Campylobacter jejuni, Citrobacterusus, Citrobacter freundii, Enterobacter cloacae, Escherichia coli, Haemophilus influenzae, Haemophilus parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Straissergioerioerius geriomeriella geriorioerioeriususererususererususererususererususererer , Serratia marcescens, Shigella sonnei, Shigella boydii, Shigella dysenteriae, Shigella flexneri.
He ikaika a nā Ciprofloxacin i loko o vitro a me ke kaʻina ʻana i ka mea e pili ana i kahi surrogate mark e pili ana Bacillus anthracis. Loaʻa iā Ciprofloxacin i loko o vitro ka emi iki o ka pale o ka pale (MIC) ≤1 μg / ml e pili ana i ka hapa nui (90%) o nā kānana o nā microorganism e like me kēia.
aerobic gram-microorganisms maikaʻi: Staphylococcus haemolyticus, Staphylococcus hominis, Streptococcus pneumoniae (PRSP),
aerobic gram-microorganisms maikaʻi: Acinetobacter iwoffi, Pasteurella multocida, Aeromonas hydrophila, Salmonella enteritidis, Edwardsiella tarda, Vibrio Cholerae, Enterobacter aerogenes, Vibrio parahaemolyticus, Klebsiella oxytoca, Vibrio vulnificus, Legionellainophocolila.
ʻO ka hapa nui Burkholderia cepacia a me kekahi mau kaha Stenotrophomonas maltophilia kū i ka ciprofloxacin, e like me ka hapa nui o ka nui anaerobic, a me ke komo ʻana Hoʻokomo nā huapili a Hoʻolaha Clostridium.
Lapaʻau lāʻau Hoʻolālā ʻia nā papa ciprofloxacin i hoʻopaʻa ʻia a ʻoi aku ka lohi ʻana o nā lāʻau lapaʻau ma mua o nā papa pākaua hoʻoiho maʻamau. Kūkulu ʻia nā ʻōkuhi ciprofloxacin a hoʻokuʻu koke i nā papa ciprofloxacin i hoʻololi ʻia. ʻO ka mole pharmacokinetic o ciprofloxacin mau kākoʻo e hoʻokuʻu i ka papa o 500 a me 1000 mg inā lawe ʻia i hoʻokahi lā he like ia me ka 250 a me nā papa 500 mg me ka hoʻokuʻu koke i ka wā e lawe ʻia 2 manawa i kēlā me kēia lā e like me AUC no kahi manawa 24-hola.
ʻO ka nui o ka hoʻoili no ka iv intravenous ciprofloxacin e pili ana i ka 2.1-12.7 l / kg kino kino. Nā hopena o nā haʻawina i hana ʻia me ka waha a me / ma ka hoʻohana ʻana o ciprofloxacin, hōʻike ʻia, e pili ana i ke ʻano o ka hoʻohana ʻana, komo ka lāʻau i loko o nā ʻili like ʻole. ʻO ka paa ʻana o ciprofloxacin me nā ʻōlima serum o 20-40%. 4 mau mea metabolite i hōʻike ʻia ma ka urine i hoʻopaʻa ʻia. Ua emi iki kēia mau metabolites i kahi hana antimicrobial ma mua o ciprofloxacin i loli ʻole. Hoʻomaka holoʻokoʻa kēia mau metabolites i loko o 24 mau hola ma hope o ka noi o ka lāʻau. ʻO nā kinetics-hoʻokuʻu ka wa i mālama ʻia o nā ciprofloxacin e like me nā mea i hoʻokuʻu koke ʻia i nā papa ciprofloxacin. Ma kahi o 35% o kahi kūlohelohe waha ua excreted i hoʻololi ʻia i ka urine. Hiki i ka hana ʻohi ʻana ma kahi kokoke i 24 mau hola ma hope o ka hoʻohana ʻana i ka lāʻau. Ma kahi o 20-35% o kahi waha o ka waha o ciprofloxacin e hoʻokuʻu koke i loko o nā ōla no nā lā 5. I nā maʻi me ka hana renal hōʻemi, lōʻihi ka lōʻihi o ka hapalua o ke ola ciprofloxacin.

Pākuʻi helu

film-coated tablet paʻa-hoʻokuʻu papa.

i kēlā me kēia papa paʻi kiʻi ʻoniʻoni ʻia: Cyfran OD 500 mg
Mea waiwai koʻikoʻi: ciprofloxacin - 500 mg. Tsifran OD 1000 mg
Mea waiwai koʻikoʻi: ciprofloxacin - 1000 mg.
Nā mea kū'ē: sodium alginate (Keltone LVCR), hypromellose, sosa bicarbonate, crospovidone (CLM), magnesium stearate, colloidal silicon dioxide (200), talc.

Wīlō kaulike:
Opadry keʻokeʻo 31B58910, kāwili talcum, hypromellose, wai maʻemaʻe, nā aniani ʻeleʻele no ka ʻatikala (Opakod -S-1-17823 ʻeleʻele).
ka hui ʻana o ke keʻokeʻo opadra keʻokeʻo 31B58910: hypromellose, lactose, titanium dioxide, macrogol 400, e ulana ana i ka wā o ka hana.
ka hui pū me ka: shellac 45% (20% esterified) i loko o ka ethanol, isopropanol, n-butanol, propylene glycol, kūmole ʻoliʻala 28%, ʻeleha hao hao ʻeleʻele.

E hoʻokuʻu i ke ʻano

Nā papa hana maʻa lōʻihi, hoʻopili ʻia nā kiʻi 500 mg, 1000 mg. Nā papa papa 5 i ka palupalula, ka mea i loaʻa i ka alumini foil ma kekahi ʻaoʻao a me ka alumini foilahi i kālai ʻia me kahi kiʻi polyamide a me nā kiʻi PVC ma kahi ʻē aʻe, 1 a i ʻole 2 mau ʻaha paha i loko o kahi pahu pahu me nā kuhikuhi i ka hoʻohana ʻana.

Nā Papaʻi "Tsifran OD 500 mg"
ʻO nā papa hana hoʻohālikelike, mai ke keʻokeʻo a kokoke i ke keʻokeʻo, hoholo ʻia i ke kiʻi, ma kekahi
ʻaoʻao o ka papa ʻaina meaʻai e paʻi ʻia "Cifran OD 500MG".

ʻLelo papaʻi i kahi hakahaka:
papakeʻa mai ke keʻokeʻo a hiki i keʻokeʻo.

Nā Kūlana "Tsifran OD 1000 mg"
ʻO nā papa ʻonekona hāulaʻi, mai ke keʻokeʻo a kokoke i ke keʻokeʻo, kāwili ʻia nā kiʻi ʻoniʻoni, “Cifran OD 1000MG” i paʻi ʻia ma kekahi ʻaoʻao o ka papa me ka ipu kai.
ʻO ke ʻano o ka papa ʻaina i kahi wā hoʻomaha: neʻe ʻia mai ka lehulehu mai ka keʻokeʻo a kokoke i ke keʻokeʻo.

Inoa Kūʻai ʻole honua

ʻO ka inoa kālepa no kēia lāʻau lapaʻau ʻo Cifran®. ʻO ka inoa makemake ʻole honua ʻo Ciprofloxacin (Ciprofloxacin). I kā Latin - Ciprofloxacinum.

Hoʻohana ʻo Ciphran i ka hapa nui o nā bacteriophages a me nā kaula o nā microorganisms pathogenic.

J01MA02 Nā lāʻau lapaʻau huapuni systemic.

Ka hana lāʻau lapaʻau

Hoʻohana ʻo Ciphran i ka hapa nui o nā bacteriophages a me nā māka o nā microorganism pathogenic e kū pono i aminoglycosides. No laila, ʻōlelo aku ka poʻe ola olakino i kēia lāʻau lapaʻau e pale aku i nā hoʻopili i hui ʻia e ka anaerobic, aerobic bacteria a me ka maʻi ʻeha o ka gastrointestinal. ʻO ka hopena bactericidal o ciprofloxacin ma muli o ka hiki ke hoʻokahe i ka hōʻailona o nā enzymes i pono no ke ola o ka microorganism.

Pono ke kauka ola olakino iā Cifran e hakakā i ka hoʻopili ʻana i nā maʻi maʻi.

Lapaʻau lāʻau

Penei ka hoʻoili koke ʻana mai nā ʻaoʻao ʻokoʻa o ka pūpū liʻiliʻi. Loaʻa ka lōʻihi o ke koʻikoʻi o ka lāʻau i ke kino ma hope o 1-1,5 mau hola ma hope o ka hoʻokele ʻana. I kēia hihia, ʻaʻole e pili ana ka hoʻohana ʻana i ka meaʻai i ka nui o ke komo ʻana.

Hoʻolālā ʻo Biotransform ma loko o ke ake. Hoʻomaka ia me ka hōʻoki ʻia mai ke kino ma hope o nā hola 3-5, ka nui me ka urine a ma kekahi hapa ma waena o nā ʻōpū. I ka poʻe me nā maʻi o ka pēpē, ʻoi aku ka manawa o ka hapalua a me ka hopena o ka lāʻau.

He aha ka mea e kōkua ai

Ua kuhikuhi ʻia ia no nā maʻi i hoʻopiʻi ʻia a me nā hōʻiliʻili ʻia e nā maʻi.

• palapala keleawe-pulmonary,
• Nā hui ENT
• he maka
• ka waha e pili ana
• ʻōiwi a me ka urogenital system,
• ʻōpū o ka ʻōpū
• ʻōnaehana musculoskeletal.

No nā keiki, ua kuhikuhi ʻia kēia lāʻau lapaʻau no ka mālama ʻana i nā pōʻino i pili me ka cystic fibrosis pulmonary.

Nā Hoʻohui

ʻAʻole kuhikuhi ʻia ke kāleka inā loaʻa ka:

• ka uluʻana i nā lāʻau lapaʻau mai ka hui quinolone,
• ʻitislelo poloka
• kekahi ʻano o ka epilepsy.

ʻAʻole ʻōlelo ʻia ke kamepiula no ka hoʻohana ʻana i ka wā hāpai a i ka wā lactation.

Eia kekahi, e like me nā kauoha i hoʻohana ʻia, ʻaʻole pono kēia mea hana no ka hoʻohana ʻana i ka wā hāpai a i ka wā lactation.

Hoʻomaopopo ʻia nā keiki a me nā ʻōpio ke hakakā wale i nā maʻi e kū mai ka cystic fibrosis a i ʻole ka hoʻoweliweli ʻana o ka maʻi anthrax.

ʻAʻole hoʻohana ʻia ʻo Ciphran me ka tizanidine.

Me ka mālama pono

Me ka mālama aka, ua kau ʻia nā maʻi maʻi makahiki, a:

• me ka cerebral arteriosclerosis a hoʻonui i ka hoʻoikaika intracranial,
• me ka maʻi puʻuwai
• me ka pohō o nā electrolytic,
• me nā renal a ma / a he pathology hepatic paha,
• me ka maʻi noʻonoʻo a me nā maʻi epilepsy.

Lawe ʻia ka Digital 500 ma mua o ka ʻai, me ka ʻole o ka ʻino a me ka inu ʻana i ka wai.

He mau palena kona inā e ʻike ʻia kekahi ma nā maʻi o ka apparatus ligamentous i hoʻonāukiuki ʻia e ka lawe ʻana i nā fluoroquinolones.

Pehea e lawe ai iā Tsifran 500

E lawe ma mua o ka ʻai, me ka ʻaika ʻole ʻana a me ka wai wai.

ʻO nā pākeke no ka mālama ʻana i nā maʻi e kū mai ana:

• i ke kukui a me nā kikooho - 0.25-0.5 g ʻelua i ka lā,
• i kahi hoʻopiʻi paʻakikī a paʻakikī paha - 0.75 g ʻelua i ka lā hoʻokahi.

Hoʻoholo ʻia ka lōʻihi o ka mālama ʻia e ke ʻano a me ka paʻakikī o ka papa o ka lesion infectious. Nā kauka lāʻau lapaʻau i kuhikuhi kūʻokoʻa ʻia e kekahi kauka.

ʻO ka palena loa o ka lāʻau lapaʻau ka ʻona o 0.75 g, i kēlā me kēia lā - ʻaʻole iʻoi aku ma mua o 1,5 g.

I nā maʻi o nā ate a i ʻole nā ​​lolo, ʻo ka nui loa o ka nui o ka lā ma mua o 0.8 g (0.2-0.4 g i kēlā me kēia mau hola 12.

Inā loaʻa i ka mea maʻi ka maʻi maʻi, hoʻolaʻa ʻia nā lāʻau antibiotik e nā kauka i ka ʻokoʻa ma ke ʻano o ke kauka.

Me ka maʻi diabetes

Ua manaʻoʻiʻo Ciprofloxacin e hoʻonui i ka hana a ka lāʻau hypoglycemic. No laila, ke hui pū ʻia kēia waiwai, no ka laʻana, me ka glibenclamide a i ʻole glimepiride, hypoglycemic syndrome e ulu.

Inā loaʻa i ka mea maʻi ka maʻi maʻi, hoʻolaʻa ʻia nā lāʻau antibiotik e nā kauka i ka ʻokoʻa ma ke ʻano o ke kauka.

Mai ka pūnaehana cardiovascular

Keʻano o nā palpitations, arrhythmia, tachycardia, e hoʻololi i ke kaʻe o ke koko.

Hiki i ke Tsifran ke hoʻopiʻi i nā hopena ʻaoʻao i ke ʻano o ka palpitations o ka naʻau, nā arrhythmias, tachycardia, ka hoʻololi i ke koko.

Pūnaehana pīhoihoi waena

Hōʻike kekahi mau mea maʻi i nā hōʻailona o ka asthenia, nā hana hoʻomaha, ka hopohopo, ke hoʻolohe ʻana, ka hoʻāʻo ʻana ke ʻano, a me nā mea ʻē aʻe.

ʻO kekahi mau mea maʻi e hoʻomau i nā wahi hiamoe hiamoe.

ʻO ka edion Angioneurotic, rashes ka ʻili, kaʻeha a me nā hopena anaphylactic (kahi luhi).

Nā ʻōlelo kikoʻī

ʻO ka poʻe maʻi nona ka mōʻaukala olakino e pili ana i ka ʻike e pili ana i ka epilepsy, ke koi ʻana, nā vascular pathologies a me nā palaka olakino o ka lolo i ka hopena o ka pane ʻole ʻana mai ka pūnaehana loko waena. I kekahi mau hihia, ulu mai kahi kūlana o ka maʻi maʻi, e ka ʻimi ʻia me ka hoʻāʻo suicidal. No laila, ua kuhikuhi ʻia kēia lāʻau lapaʻau wale nō no nā hōʻailona koʻikoʻi.

Ke hoʻohana nei i kēia lāʻau lapaʻau, pono e pale i ka hoʻouka ʻana i ka lā, ʻoiai ua hāʻawi i ka hōʻike ʻana o ka photosensitivity.

Hoʻohana i ka wā kahiko

No nā mea maʻi me ka pale ʻole ʻia o ka maʻi ma mua, i mālama mua ʻia me ka glucocorticosteroids, aia kahi hopena o ka wehe ʻana i ka tendon Achilles. No laila, i ka wā e puka mai ai nā hōʻailona o ka tendonitis, pono e hoʻopau ʻia ka hoʻokele ʻo Cyfran.

No nā mea maʻi me ka pale ʻole ʻia o ka maʻi ʻeha, aia kahi hopena o ka wehe ʻana o ka tendon Achilles.

Ke keu

Nā hōʻailona: ke ʻano o ka haunaele, ke poʻo, ka ʻōpū o ka nāwaliwali, nausea, a me ka luaʻi. I nā hihia o ka overdose, pono e hoʻokō i nā hana detoxification maʻamau.

• hihiki
• ka lā hoʻonohonoho o nā emetics
• ka hana ʻana o ka calcium a me nā huahana magnesium,
• ka hoʻohana ʻana o nā puʻupuʻu nui.

Eia kekahi, pono e nānā i ka hana o ka ʻōnaehana urinary, ʻoiai me ka hoʻohana ʻole ʻana o ka lāʻau, ʻike ʻia nā hopena o nā pakanā o nā maʻi.

Hoʻopili pū me nā lāʻau ʻē aʻe

Me ka mālama like ʻana o nā lāʻau lapa puʻuwai, antidepressants a me nā antipsychotics, ua kuhikuhi pū me ka mālama.

I ka hui pū me Theophylline, hoʻonui ia i kona hopena a kōkua i ka hoʻokuʻu ʻana i ke kino.

Me ka hoʻohana like ʻana me ka phenytoin, ua nānā ʻia kahi loli ma kona neʻe i ke koko. E haʻalele i ka hoʻomaka ʻana o nā kūlana hoʻomanawanui, pono ka mālama ʻana i ka mālama phenytoin i ka manawa holoʻokoʻa o ka hopena hui.

ʻO nā NSAID (ʻoi aku ma mua o ka acetylsalicylic acid) i ka hui pū me nā dosis kiʻekiʻe o nā quinolones e hiki ai i nā mea kiaʻi.

Hoʻohui ʻo Cyclosporin i ka Cyfran e kōkua i ka hoʻonui i hana i loko o ke kino.

Hoʻopau nā Probenecid i ka hoʻokuʻu i nā ciprofloxacin i loko o ka urine.

I ka hui me nā methotrexate, e hoʻolei ana i kona halihali tubal a me ka hoʻonui ʻana i ka kao.

ʻO ka hoʻohana paʻakikī ʻana o Cyfran me nā vitamin K antagonist e hoʻonui i ko lākou mau anticoagulant.

I ka hui pū ʻana me ka ropinirole a i ka lidocaine paha, piʻi i ka paʻakikī o ka ulu ʻana o ka hopena ʻaoʻao.

I ka hui pū me nā warfarin, hoʻonui i ka nui o ke kahe.

Ka analogue hoʻokolohua o Cifran no ka waiwai ikaika ʻo Ciprolet.

Nā mea hoʻohālikelike hou o nā mea ikaika:

• Alcipro
• Tsiprolet,
• Ciprolone
• Tsiprobay,
• Waiopane
• Tsiprosan
• Tsiprosin
• Kaleikoli,
• Ciprofloxabol,
• Kokolilox
• Citral
• Tsifloksinal,
• Tsifran OD,
• Tsifran ST,
• ʻO Ecocifol a me nā mea ʻē aʻe.

Hoʻoholo ʻia ka lōʻihi o ka mālama ʻia e ke ʻano a me ka paʻakikī o ka papa o ka lesion infectious.

Nā hōʻike hōʻike a nā kauka a me nā mea maʻi e pili ana iā Tsifran 500

ʻO Berezkin A.V., ka mea lapaʻau, Mezhdurechensk

ʻO kahi antibiotic ākea ākea i hoʻohana ʻia i ka hana hoʻokipa, dentistry, gynecology, urology a me nā meaʻokoʻa. ʻO wau ponoʻī ke kuhikuhi i kēia lāʻau lapaʻau me ka liʻiliʻi ʻole, aia wale nō inā hōʻike ʻia a i ʻole he prophylaxis ma hope o nā hana purulent a me nā hōʻeha. Manaʻo wau he kūpono a kūpono hoʻi i ka hoʻohana ʻana.

Kornienko L.F., gynecologist, Irkutsk

Ua kūpono kēia lāʻau lapaʻau no ka mālama ʻana i nā maʻi maʻi gynecological a me nā maʻi. Hoʻoholo ka ākea ākea o ka hana i ka hopena o ka pono.

Alla, 25 makahiki, Ufa

Kuhi ʻo ia i kahi ʻehaʻeha koʻikoʻi, a kuhikuhi ke kauka i 500 mg o nā papa Cyfran i hoʻokahi manawa i ka lā. Ma kahi kīhāpai kokoke loa i nā kūpono kūpono o kēia antibiotika ʻaʻole. Ua kūʻai au ma loko o kahi waihonaʻauʻau 250 mg a lawe i nā kumukūʻai 2 i hoʻokahi manawa. Ua hala ʻo Angina i 3 mau lā, akā ʻaʻole ia i kalai i ke papa. Lawe ʻia he 10 lā. Hoʻoweliweli ka hopena o ka ʻaoʻao: ʻo ka hoʻomaka koke ʻana o ka tachycardia me ka dysbiosis ʻo ia ka hui like ʻole. ʻĀnō wau e makaʻala i kēia lāʻau lapaʻau a ʻaʻole wau makemake e lawe i ke kauka.

Nā hōʻailona no ka hoʻohana lāʻau ʻana ʻo Tsifran OD

ʻO nā maʻi i hoʻopiʻi ʻole a me ka paʻakikī e nā pathogens i makaʻala i ka ciprofloxacin:

• ʻeha nā maʻi ʻeha: pomi kaʻi ʻia e nā Klebsiella spp., Enterobacter spp., Proteus spp., Escherichia coli, Pseudomonas aeruginosa, Haemophilus spp., Moraxella catarrhalis, Legionella a he staphylococci,
• nā maʻi o ka pepeiao waena a me nā sinus paranasal,
• nā hopena o ka ʻōpū o ka ʻōpū, ka maʻi pāpaʻi o ke kūpaʻa ʻana o ke kano, ka ʻāpana palaka a me nā pāpaʻi biliary, me ka peritonitis hoʻi,
• akeiy a me nā maʻi pihi
• maʻi pelvic (gonorrhea, adnexitis, prostatitis),
• nāʻiʻi o ka ʻili a me nā pāwī palupalu,
• nāʻiʻaʻi o nā iwi a me nā hui.

Ke hoʻohana nei i ka lāʻau ʻo Tsifran OD

Lawe ʻia ka lāʻau ma hope o ka ʻaina. Pio ke papa āpau. Mai hōʻoki ʻia, nā ʻoki ʻana, a me ke kele ʻana paha i ka papa. Ua koho ʻia ka ʻona no kēlā me kēia maʻi e mālama i ke kaumaha o ke kino, ke ʻano o ka pathogen, ka ʻike ʻana o ke pathogen, ke ʻano o ke ʻano o ke ʻano o ka mea maʻi, a me ka hana pūpū a me ka hana kino. Aia ka lōʻihi o ka mālama ʻana i ka hōʻeha o ka maʻi a he maʻamau ʻo 7-14 mau lā.Akā, no nā hōʻeha paʻakikī a paʻakikī paha, pono paha ke mālama ʻia.

ʻO ka hopena kaulike o iv ciprofloxacin

500 mg (1 papa) Cyfran OD 1 ka manawa i ka lā

200 mg i kēlā me kēia mau hola 12

1000 mg (1 papa) Cyfran OD 1 ka manawa i ka lā

400 mg kēlā me 12 hola

I ka poʻe maʻi me ka hana renal impaired, ʻoi aku me ka maikaʻi ʻole o ka renal nui, koi ʻia ka hoʻoponopono ʻana.
Aia ka papa ma lalo nei i nā ʻōkuhi dosage no ka hoʻohana ʻana i nā mea maʻi me ka hana ʻoi aku ka maʻi ʻole.

ʻO ka hoʻopukapukaʻana o Creinine, ml / min

Hōʻoia Manaʻo ʻia

Nā Papa Kūlana Tsifran OD 500-1000 mg 1 ka manawa i kēlā me kēia lā

ʻAʻole kōkua ʻia nā papa cifran OD; hiki ke hoʻohana ʻia nā papa ciprofloxacin konvensional i loko o kēia aʻe: 250-500 mg o ciprofloxacin i kēlā me kēia mau hola 18.

ʻO nā mea maʻi ma ka hemo- a i kēlā me kēia dialysis peritoneal

ʻAʻole i ʻāpono ʻia nā Papa Cifran OD, hiki ke hoʻohana ʻia nā papa pākahi ma ka ʻōlelo aʻe: 250-500 mg o ciprofloxacin i kēlā me kēia 24 hola (ma hope o ka dialysis)

* I ka poʻe maʻi me ka cleinine clearance ≤30 ml / min me ka paʻakikī o ka urinary tract maʻi a me ka maʻi kikoʻī o ka pyelonephritis, ʻo ka pākīpeka ʻo 500 mg o Cyfran OD hoʻokahi i ka lā.

Inā ʻike ʻia ka ʻike ʻana o ka creatinine ma ka serum o ke koko, hiki ke hoʻohana ʻia i kēia ʻōpana ma lalo nei e loiloi ai i ka hoʻomaʻemaʻe ʻana i hana aku ai:

no na kane:


clearance hana (ml / min) =

Ke kaumaha kino (kg) × (140 - makahiki)

72 (plasma hana (mg / dl))

ʻAʻole pono e hoʻoponopono i ke ʻano o ka ciprofloxacin no nā poʻe maʻi me ka papa paʻa o ka cirrhosis ate ate. Eia nō naʻe, ʻo ka pharmacokinetics o ciprofloxacin i loko o nā mea maʻi me ka ʻoi aopio hemahema ʻaʻole e hoʻopili pono i ka holo.

Nā hopena hopena o ka lāʻau Tsifran OD

ʻĀkau ≥1, ≤10%
Nā hui luhi: ninia, huehue.
ʻIli: ʻili ka ʻili.
ʻĀkau ≥0.1, ≤≤1%
ʻO ke kino holoʻokoʻa: ʻeha ka ʻōpū, candidiasis, asthenia.
Nā hui luhi: hoʻonui i ka transaminases hepatic: AlAT, AsAT, phosphatase alkaline, luaʻi, dyspepsia, anorexia, flatulence, bilirubinemia.
Hematopoietic ʻōnaehana: eosinophilia, leukopenia.
ʻŌnaehana urinary: ua hoʻonui ʻia creatinine, urea nitrogen.
ʻŌnaehana musculoskeletal: aolaila.
CNS: hoʻomāʻeha, ʻeha, lohi ka hiamoe, hoʻomāhuʻe, haunaele.
ʻIli: ʻeha, kapa ʻāʻī o kahi ʻano maculopapular, urticaria.
Nā kumuwai o nā kumuwaiwai: nā kuhi hewa.
ʻĀkau ≥0.01, ≤≤0.1%
ʻO ke kino holoʻokoʻa: ʻeha, hōʻeha, ma ka ʻōpū, hōʻeha ma hope o ka umauma.
Pūnaehana Cardiovascular: tachycardia, migraine, syncope, vasodilation, hypotension.
Nā hui luhi: kandidiasis (waha), jaundice, jaundice cholestatic, colse pseudomembranous.
Pūnaehana koko a me ka ʻōnaehana lymphatic: anemia, leukopenia (granulocytopenia), leukocytosis, kahi hoʻololi i ke pae o prothrombin, thrombocytopenia, thrombocythemia (thrombocytosis).
Hypersenspikino: maʻi pālohelohe, maʻi ʻomaʻo, hopena anaphylactic.
ʻO ka maʻi pā ma ka hopena: edema (peripheral, vascular, facial), hyperglycemia.
ʻŌnaehana musculoskeletal: myalgia, huehue i nā ʻaniani.
CNS: migraine, hallucinations, sweating, paresthesia (peripheral paralgesia), hopohopo (makaʻu, hopohopo), ʻano hoʻomaha (nightmares), convulsions, hypersthesia, ʻehaʻeha, haʻalulu.
Pūnaehana lawelawe: dyspnea, lemaia lema.
ʻIli: Hōʻike Photosensitivity
Nā kumuwai o nā kumuwaiwai: tinnitus, kamaʻilio kūwaho (me ka nui o ke kani ʻana o ke kani), ʻike maka ʻole (ʻike anomalies), diplopia, chromatopsia, nalowale o ka ʻono (ʻeha hoʻomaʻamaʻa).
ʻŌnaehana Genitourinary: ARF, hana i ʻole ke koikoi pūlima, kandidiasis vaginal, hematuria, crystalluria, interstitial nephritis.
Nioli ≤0.01%
Pūnaehana Cardiovascular: vasculitis.
Nā hui luhi: kandidiasis, ate mikrosis (aneane loa - ke neʻe nei me ka hoʻomohala ʻana o ka hana ola ʻana i ke ola), pseudomembranous colitis me kahi hopena momona hiki, pancreatitis, hepatitis.
Pūnaehana koko a me ka ʻōnaehana lymphatic: hemolytic anemia, petechiae, agranulocytosis, pancytopenia (me ka hoʻoweliweli ʻana i ke ola), ka pale ʻana o ka hana a ka iwi molowa (me ka hoʻoweliweli ʻana i ke ola).
Hypersenspikino: hāʻeha (anaphylactic, life-hoʻoweliweli), ʻāwīwili, kahi ʻano e like me ka maʻi serum.
ʻO ka maʻi pā ma ka hopena: ka hoʻonui ʻana i ka hana o amylase a me / a lipase koko.
ʻŌnaehana musculoskeletal: myasthenia gravis, tendonitis (ʻoiʻo Achilles tendon tendonitis), ʻāpana ʻāpana a hoʻopau piha paha o ka tendon (ʻoiʻo Achilles tendon).
CNS: nā hewa koʻikoʻi o nā ʻōpū nui, ka hiki ke mālama o ka lewa, ka maʻi psychosis, ka hypertension intracranial, ataxia, hypersthesia, tic.
ʻIli: petechiae, erythema multiforme, erythema nodosum, Stevens-Johnson syndrome, necrolysis epidermal (ʻ syndromelelo o Lyell), nā ʻupena o ka ʻekena paʻa mau.
Nā kumuwai o nā kumuwaiwai: parosmia, nalowale o ka scent (e ʻoi aʻe ka hoʻololi i ka wā i pau ai ka lāʻau).

Nā Pāʻaleʻa Kūleʻa Cifran OD

ʻO ka hoʻohana like ʻana o tizanidine a me ciprofloxacin ua contraindicated. E like me nā quinolones ʻē aʻe, hiki i ka hoʻohana hoʻohui ʻana o ciprofloxacin me theophylline ke hoʻoulu i ka hoʻonui ʻana o ka theophylline concentrations i ka serum o ke koko a me ka lōʻihi o kona hapa hapa. Hiki i kēia ke hoʻonui i ka hopena o nā hopena pili i ka pili o theophylline. Inā hiki ʻole ke hoʻohana ʻia ka hoʻohana ʻana i kēia mau lāʻau, pono e nānā ʻia ka pae serum theophylline a me ka hoʻoponopono ʻia ma muli.
ʻO kekahi quinolones, me ka ciprofloxacin, e hoʻopili i ka metabolism caffeine. Hiki i kēia ke alakaʻi i kahi hoʻohemo o ka caffeine a me ka hoʻolōʻihi i ka hapalua-ola mai ka serum.
Ka hana like ʻole o kekahi lāʻau lapaʻau o ka papa quinolone, me ka ciprofloxacin, me nā hui cationic multivalent, e like me nā antacids e loaʻa ana i ka magnesium a i ka alumini hydroxide, sucralfate, didanosine chewable tablets, a i nā huahana nā calcium, ka hao a me ka zinc, hiki ke hoʻemi nui i kona komo ʻana, ma muli o ka lawe mai i ke kikoo i loko o ka serum koko a me ka urine hoʻohaʻahaʻa loa ʻia ma mua o ka mea pono.
ʻO nā hoʻohālikelike o nā mea hoʻokipa histamine H2, maopopo, ʻaʻole i pili nui i ka bioavailability o ciprofloxacin. Hoʻemi iki paha nā papa o Cyfran OD (20%) inā ua hoʻohana like ʻia me ka omeprazole.
ʻO kahi hoʻololi i ka pae serum phenytoin pae (hoʻonui a hōʻemi paha) i nānā i nā poʻe maʻi i lawe i ka ciprofloxacin i ka manawa like.
ʻO ka hoʻohana pū ʻana o ciprofloxacin me sulfonylurea ʻaʻole i alakaʻi i ka hypoglycemia koʻikoʻi.
ʻO ka loaʻa ʻana o kekahi quinolones, me ka ciprofloxacin, i pili me ka hoʻonui pōkole o ka serum creatinine i nā mea maʻi e lawe ana i ka cyclosporine ma ka manawa like.
Ua hōʻike ʻia nā quinolones, me ka ciprofloxacin, e hoʻoikaika ana i ka hana o ka warfarin anticoagulant waha a me kāna mau mea waiwai. Inā pono, e mālama pono ka hoʻohana ʻana i kēia mau lāʻau i ka manawa prothrombin i nā manawa a me nā hōʻailona o ka coagulation koko. Hoʻopilikia ka Probenecid i nā mea huna o ciprofloxacin e nā tubula renal, ma muli o ke kahe o ke ciprofloxacin i loko o ka serum o ke koko. Pono e noʻonoʻo ʻia kēia mau kūlana inā ke lawe nei ka mea maʻi i nā lāʻau ʻelua i ka manawa like.
ʻO ka halihali Methotrexate e nā tubula renal i hiki ke paʻa me ka hoʻohana pū ʻana o ciprofloxacin, hiki ke piʻi aʻe i ka pae i loko o nā pae methotrexate plasma. Hiki i kēia ke hoʻonui i nā hopena kūlohelohe ma muli o methotrexate. Pono nā mea maʻi e loaʻa ana i ka lāʻau methotrexate e nānā kokoke inā ciprofloxacin therapy e hāʻawi iā lākou i ka manawa like.
Hoʻonui nui ʻo Metoclopramide i ka hoʻopili ʻana o ka ciprofloxacin e lawe pono ʻia, a laila e hoʻonui ai i ka manawa e hiki ai i kona kūʻai kiʻekiʻe ma nā kaila koko. Eia naʻe, ʻaʻohe hopena i ka bioavailability o ciprofloxacin i hoʻomaopopo ʻia.

Nā hui ahonui kūikawā

I kahi hana renal impaired: I nā mea maʻi me ka hana ʻole o ka pale lūlū, ka hapalua o ke ola o ka ciprofloxacin i hoʻonui iki i ka hapa. I kēia hihia, pono ke hoʻoponopono ʻana i ka hoʻoponopono ʻia dosage.

Ma kahi o ka hana hoʻopiʻi lēwaʻeha: Ma nā haʻawina mua i nā poʻe maʻi me ka papa paʻa o ka cirrhosis o ka ate, ʻaʻohe loli nui i ka pharmacokinetics o ciprofloxacin i hoʻomaopopo ʻia. Eia nō naʻe, ʻaʻole i mālama ʻia nā haʻawina e pili ana i ka kinetics o ciprofloxacin i loko o nā mea maʻi me ka hoʻomaʻemaʻe ʻōiwi.

Hoʻohana i ka wā hāpai a i ka wā o ka umauma

ʻAʻole kōkua ʻia ʻo Cifran OD no ka hoʻohana ʻana i ka wā hāpai.
Hoʻopili ʻia ʻo Ciprofloxacin i loko o ka waiū umauma, no laila, i ka wā lactation, inā ʻoe pono e hoʻohana i Cifran OD, a laila, e pili ana i ke koʻikoʻi o kona hoʻohana ʻana no ka makuahine, pono ʻoe e hoʻoholo inā hemo i ka lawe ʻana i ka lāʻau lapaʻau a ʻo ka umauma.

ʻLoe a me ke kākele

I loko.
ʻAʻole ʻoe e wāwahi, ʻūlū, ai ʻole ke luku ʻia nā papa. Pono e kiʻi ʻia nā papa ma hope o ka ʻaina ʻana, me ka wai nui.
Hoʻomau ka hoʻohana ʻana o Tsifran OD no ka liʻiliʻi o 2 mau lā hou ma hope o ka nalowale piha ʻana i nā hōʻailona o ka maʻi.
Nā noiʻi no ka pākeke.

Ke hoʻoponopono ʻana i ka hoʻoponopono ʻia ʻana ma ka papau ʻole:
Ma kahi o ka hana lēpa ʻole kīnā, ʻo ke ʻano o ka hoʻoponopono ʻana i kēiaʻano no nā pākeke.

Inā ʻike ʻia ka minamina creinine plasma, ua ʻōlelo ʻia ke ʻano ʻōkuhi ma lalo nei
nā wehewehe ʻana o ka hana hoʻopale hana:
Kāne:

Hōʻailona ke kūlohelohe (ml / min.) = Ke kaumaha o ke kino (kg) x (140 - makahiki) / 72 x serum creatinine concentration (mg%)
Wahine:
Hoʻolaha ʻo Creatinine (ml / min.) = 0.85 x kuhikuhi i hoʻohālikelike ʻia no nā kāne.

Loaʻa ka hopena

Mai ka pūnaehana hana ʻana: nausea, luaʻi, ʻeha, ʻeha ʻōpū, flatulence, anorexia, jaundice cholestatic (ʻoi aku hoʻi i nā mea maʻi me nā maʻi o ka palau ma mua), hepatitis, hepatonecrosis.

Mai ka ʻōnaehana hoʻonāukiuki: dizziness, photophobia, insomnia, paresthesia, irritability, headache, meningkat momona, hopohopo, haʻalulu, "nightmare" moeʻuhane, peripheral paralgesia (anomaly in the percept of pain), hoʻonui ulu intracranial, confingness, depression, hallucinations, and also other manifestations nā hopena psychotic (ka holomua i kekahi manawa i nā mea e hōʻino ai ka mea maʻi iā ia iho), migraine, nāwaliwali, ka trombosis a me ke kuʻuna.

Mai nā ʻike: nā haunaele i ka hoʻāʻo a me ka ʻono, ʻike ʻia o ka ʻike (diplopia, discoloration), tinnitus, hoʻolohe pio.

Mai ka pūnaehana cardiovascular: tachycardia, arrhythmias cardiac, hoʻemi i ke koko, ke kahe ʻana o ke koko i ka ʻili o ka maka.

Mai ka hematopoietic ʻōnaehana: eozoftft, leukopenia, granulocytopenia, anemia, thrombocytopenia, leukocytosis, thrombocytosis, hemolytic anemia.

Nā hōʻailona kuhikuhi: hypoprothrombinemia, hoʻonui i ka hana o ka transaminases "ate", hypercreatininemia, hyperbilirubinemia, hyperglycemia, hoʻonui i ka hana o ka alkatine phosphatase a lactate dehydrogenase.

Mai ka urinary system: hematuria, crystalluria (ma mua me ka hopena alkaline o ka urine a me ka diuresis haʻahaʻa), ka hopena nephritis interstitial (me ke ʻano o ka ulu ʻana o ka hiki ʻana o ka hana renal), glomerulonephritis, dysuria, polyuria, mālama i ka urinary, albuminuria, urethralugo, hoʻoneʻe i ka hana excretory nitrogen o nā keiki.

Nā maʻi kūwaha: ka ʻeha o ka ʻili, nā puaʻa, ke ʻano hoʻohālikelike me ka hele ʻana i ka puhipuhi, a me ka nānā ʻana o nā nodules liʻiliʻi e kū nei i ka scabs, fever fever, ʻōpū hemorrhages ma ka ʻili (petechiae), huehue o ka maka a larynx, dyspnea, vasculitis, erythema nodosum, erythema multiforme exudative (malignant erythema, malignant ʻO ka maʻi Stevens-Johnson), nā nekrolysis epidermal toxic (kahi o ka maʻi Lyell).

Mai ka ʻōnaehana musculoskeletal: arthralgia, arthritis, tendovaginitis, tendon ruptures, myalgia.

Nā ʻili: hoʻonui nui loa, photosensitivity, nāwaliwali laulā, superinfection (kandidiasis, pseudomembranous colitis).