Vasonite: nā ʻōlelo no ka hoʻohana ʻana, nā loiloi a me ke kumukūʻai
ʻO Vasonite ka hopena lapaʻau e pili ana i kēia:
- hoʻomaikaʻi microcirculation koko i nā wahi o nā kaʻe o ka pōʻai e hiki ke hoʻonui rūolau nā hui koko (ke aho),
- pale i nā paia o nā kīʻaha koko mai nā hopena maikaʻi ʻole (angioprotectivehoʻoiho)
- hoʻomaha i nā ʻōkohu palalike o nā paia o nā kīʻaha koko (hopena hopena vasodilating),
- pale i ka hiki ke koko o ʻōpalaola (anti-aggregation hoʻoiho)
- hoʻomaikaʻi i ka hāʻawi oxygen i nā kiko.
E hoʻokuʻu i ke ʻano a me ka ʻano
Loaʻa ka lāʻau lapaʻau i ke ʻano o nā papa i hoʻokuʻu ʻia, hoʻōla ʻia nā kiʻi, 600 mg (10 mau ʻāpana i loko o kahi palake, 2 blisters ma loko o kahi pahu pahu.
ʻO ka mea ikaika o Wasonite he pentoxifylline, e like me nā mea kōkua, ua loaʻa ka lāʻau lapaʻau:
- Nā cellulose Microcrystalline - 13.5 mg,
- ʻO ka silica silica lauleʻa - 3 mg,
- Wale a Magnesium - 4,5 mg,
- ʻO Hypromellose 15000 cp - 104 mg,
- Crospovidone - 15 mg.
Aia ka hili:
- Talc - 11.842 mg
- Hypromellose 5 cP - 3.286 mg,
- Macrogol 6000 - 3.943 mg,
- Ka loaʻa ʻana o Titanium - 3.943 mg,
- Ka polyacrylic acid (ma kahi o 30% ka laha ʻana) - 0.986 mg.
Lapaʻau lāʻau
ʻO Pentoxifylline e pili ana i nā derivatives xanthine, kahi e alakaʻi ai i ka holomua o ka microcirculation ma nā wahi me ka loaʻa o ke koko kīnā. Hāʻawi ia i ka hoʻomaikaʻi ʻana i nā ʻōlaʻi o ka rheological o ke koko (kahe koko) ma muli o ka hopena i ka deformability o nā ʻoli koko koko i loaʻa i nā loli pathological. Hoʻonui ka Pentoxifylline i ka elasticity o membranes erythrocyte, ʻae i ka platelet a me ka erythrocyte aggregation a hōʻemi i ka hoʻonui nui ʻana o ke koko.
Hoʻomoe ʻia ka hana o ka hana o ka hana ikaika o Wasonite i ka pale ʻana o ka phosphodiesterase a me ka hōʻiliʻili o ka cyclic adenosine monophosphate (cAMP) i loko o nā kōpona koko a me nā pūlapa e hoʻomālamalama i nā māla maʻa o nā moku. Hōʻemi ka pentoxifylline i ka ʻike o ka fibrinogen i loko o ke kaila koko a hoʻōla i ka fibrinolysis, ka mea e alakaʻi ai i ka emi ʻana o ke kahe koko a me ka hoʻomaikaʻi ʻana i kona mau ʻāpana rheological, a hoʻomaikaʻi hou i ka saturation oxygen okena ma nā wahi e ʻike ʻia ai nā maʻi circulat, ma ka pūnaehana pili ʻana i ka pūnaehana pīpī, nā wāwae a me ka liʻiliʻi. mau pūluhi. Me nā leʻaleʻa maʻamau o nā hālā peripheral, i hui pū ʻia me nā claudication intermittent, kōkua ʻo Wazonite i ka hōʻemi ʻana i ka hōʻeha ʻana i ka hoʻomaha, hoʻopau i nā hōʻikina o nā pū bipi keiki i ka pō a hoʻonui i ka mamao o ka hele wāwae. Me nā maʻi cerebrovascular, hoʻomaikaʻi ka pentoxifylline i nā hōʻailona. Hoʻohālikelike ʻia ka waiwai o ka hopena me ka liʻiliʻi myotropic vasodilating a me ka hoʻonui ʻana i nā moku coronary, a me ka hōʻemi iki ʻana i ka huakaʻi pale huakaʻi peripheral.
Lapaʻau lāʻau
Ma hope o ka lawelawe waha, ua piha loa ka pentoxifylline mai ka ʻili kūwili. Hoʻokuʻu ʻia ia ma kahi kūlana lōʻihi, ʻo ia ka mea e hōʻoia ai i ka hoʻokuʻu mau ʻana o ka waiwai a me kona paʻa ʻana i loko o ke kino. Ka huikala o Pentoxifylline i loko o ka puʻuwai, e hele ana i ka hopena "pass mua" me ka hoʻokumu ʻana o nā metabolites hoʻonaninani ʻelua: 1-5-hydroxyhexyl-3,7-dimethylxanthine (metabolite I) a me 1-3-carboxypropyl-3,7-dimethylxanthine (metabolite V). ʻO ka pae o ka metabolites I a me V i ke koko plasma, ma kēlā, he 5 a me 8 mau manawa i ʻoi aku ma mua o ka pentoxifylline ponoʻī. I ka wā e hoʻoponopono ai ka waha o Wazonite i ka papa ʻaina, ʻo ka nui o ke kaila o ka pentoxifylline a me kāna mau metabolite hoʻoikaika i ka plasma koko e nānā ʻia ana he mau hola 3-4 ma hope o ka lawelawe ʻana, a hoʻomau ka hopena therapeutic no nā hola 12. Lawe ka hana o ka lāʻau i ka mea nui ma o nā keiki (ma kahi o 94%) i nā ʻano o nā metabolites. E hoʻolilo ʻia i loko o ka waiū umauma. Me nā hana heʻeha koʻikoʻi, hāʻule ka paʻakaha o nā metabolites. Me ka hana pūpū hemahema, ʻike ʻia kahi hoʻonui i ka bioavailability a me kahi hoʻonui i ka hapalua-ola.
Nā hōʻailona no ka hoʻohana ʻana
Wahi a nā ʻōlelo kuhikuhi, ua hoʻohana ʻia ʻo Vasonite i kēia mau pilikia penei:
- Nā maʻi hōʻeha a me nā pilikia koʻikoʻi cerebrovascular o nā ischemic kumu,
- Dyscirculatory and atherosclerotic encephalopathy, angioneuropathy (maʻi ʻo Raynaud, paresthesia),
- ʻO ka pilikia o ke alo o ka maka (ke nānā a me ka hoʻōla ʻole o ka circulat i ka choroid a i ʻole retina o ka maka),
- ʻĀwili o ka pōʻai o peripheral e kū i ke kua o ka maʻi maʻi, ka atherosclerotic a me nā ʻōnaehana maʻi (e komo pū ana me ka claudication intermittent i hoʻolauna ʻia e ka endarteritis, atherosclerosis, a me ka angathyathy maʻi).
- ʻO nā maʻi ʻeha o ka trophic i kū mai i kahi kiʻi o nā maʻi mikocular a me ka maʻi arterial (ulia trophic, frostbite, post-thrombophlebitis syndrome, gangrene),
- Hoʻohālikelike ʻia o ka pepeiao waena o nā kumu vascular, i hele pū me ka nalo lohe.
Pēlā nō, Vasonitis e kauoha ʻia no ka mālama ʻana i ka hopena me ka hopena o ka maʻi cerebrovascular ma ke ʻano o ka atherosclerotic origin (dizziness, paʻa ʻole ka ʻike a me ka hoʻomanaʻo).
Nā Hoʻohui
ʻO nā hoʻohālikelike i ka hoʻohana ʻana o Wazonite:
- ʻO ka pīhoihoi nui
- ʻŌpalaʻi retinal
- Acokocaena myocardial infarction,
- Acorr hemagid hemena,
- Hypersensitivity i nā mea o ka lāʻau lapaʻau a me nā derivatives methylxanthine ʻē aʻe,
- ʻŌpū a me ka lactation
- ʻAʻole kau i hoʻokumu ʻia ka makahiki ma lalo o ka 18 mau makahiki (ka palekana a me ka hiki o ka lāʻau lapaʻau no kēia ʻano makahiki).
Me ka mālama aka, ua kuhikuhi ʻia ʻo Vasonite no:
- Hipotina arterialia,
- Hoʻopau ʻole nā puʻuwai naʻau
- ʻO ka haunaele o ka puʻuwai
- Atherosclerosis o ke coronary a / a i ʻole nā moku cerebral,
- ʻO nā pēpē
- Hoʻopili i ke kīkala koko
- ʻO ka ulia maʻi o ka ʻōpū a me ka duodenum,
- Nā kūlana ma hope o ka wehe ʻana o ka wā (ma muli o ke ʻano o ke kaʻe koko).
Nā ʻōkuhi no ka hoʻohana ʻana i ka vasonite: ka ʻaea a me ka helu ʻana
Pono e lawe ʻia i ka lāʻau ma ke ʻano ma hope o ka ʻaina, me ka ʻole kū ʻole i ke kūpaʻa o ka pōpoki a inu i nā ʻano wai nui.
I ka nui o nā hihia, ua kauoha ʻia e lawe i ka papa 1 o 600 mg o Wazonite i ke kakahiaka a me ke ahiahi. ʻO ka palena kiʻekiʻe loa o kēlā me kēia lā he 1200 mg.
Hoʻoholo ʻia ka lōʻihi o ka mālama ʻana a me ka hoʻoponopono ʻia ʻana e ka kauka e like me ke kiʻi o nā maʻi ʻo ka maʻi a me ka hopena therapeutic i loaʻa.
I ka loaʻa ʻana o nā poʻe maʻi e loaʻa ʻole ana i ka maʻi maʻamau ʻole (CC ma lalo o 30 ml / min), ʻaʻole pono e hoʻohana ʻia kahi nui o ka Wasonit 600 mg.
I ka poʻe maʻi me ka hōʻeha ʻana o ka maʻi maʻi hepatic, e pono ka hoʻohaʻahaʻa ʻana i ka helu ʻana i ka hoʻomanawanui ʻana.
ʻO ka mālama ʻana o nā mea maʻi me ka hoʻokahe koko haʻahaʻa, me nā mea maʻi e hōʻemi ʻia ma muli o kahi hiki ke emi i ke kahe o ke koko (hemodynamically koʻikoʻi stenosis o ka moku cerebral, i kahi ʻano koʻikoʻi o ka maʻi naʻau coronary), ua manaʻo ʻia e hoʻomaka me nā dosis liʻiliʻi. I kēia mau hihia, ʻae ʻia kahi piʻi liʻiliʻi o ka hala.
Nā hopena hopena
Hiki i ka hoʻohana ʻana o ka vasonite ke hōʻemi i kēia mau hopena:
- Mai ka pūnaehana ʻana: ka huehue, ka puki a me ka luaʻi, ʻeha ʻo epigastric, maloʻo maloʻo, ka hoʻohaʻahaʻa i ka makemake, ʻohi ʻana i ka hopohopo a me ke kaomi i loko o ka ʻōpū, ka ʻōpū o ka ʻōpū, hepatitis cholestatic, exacerbation of cholecystitis, hoʻonui i ka hana o ka alkatine phosphatase a me nā enzim poma.
- Mai ka papa kikowaena kikowaena: nā kuʻekuʻe a me ka hupa, nā pilikia hiamoe, hopohopo, nā pahu, nā hihia o ka hoʻomohala ʻana i ka meningitis aseptic,
- Mai ka pūnaehana cardiovascular: tachycardia, arrhythmia, hoʻohaʻahaʻa i ke koko, ka neʻe ʻana o ka angina pectoris, cardialgia,
- Mai ka ʻōnaehana hemopoietic a me ka homeostasis: jarang - thrombocytopenia, pancytopenia, aplastic anemia, leukopenia, hypofibrinogenemia, nā kahe (mai nā ʻōpū, nā ipu ʻeha, nā membanes a me ka ʻāʻī). Ma ke kaʻina hana o ka mālama ʻana, pono ka mālama pinepine ʻana i ke kiʻi koko o peripheral.
- Ma ka ʻāpana o ka ʻili a me ka momona subcutaneous: flush o ka maka a me ka umauma luna, hoʻonui i ka palupalu o nā kui, ka holo ʻana o ka maka, ka ʻā ʻana;
- Ma ka ʻaoʻao o nā mea ʻike o ka ʻike: ʻike maka, scotoma,
- Nā ʻano maʻi: hyperemia o ka ʻili, ka angioedema o Quincke, pruritus, urticaria, hūnū anaphylactic.
Ke keu
Me kahi overdose o Vasonitis, ke ʻano o nā hōʻailona e like me ka nāwaliwali, nā kahe, ke kahaki, hyperemia o ka ʻili, ka hoʻēmi ʻia ʻana o ke kahe koko, tachycardia, areflexia, ke kirika (chills), a me ka palupalu hiki. I kekahi manawa ke hele ʻia ka overdose o ka lāʻau me ka loiloi ʻana o ke ʻano o "kīwī kīpī", e hōʻike ana i ke koko gastrointestinal, a me nā hana tonic-clonic.
Ke hōʻike nei i ka mālama ʻana, hoʻonaninani ʻia ka gastric lavage, ukali ʻia e ka nānā ʻana i ka carbon carbon activated. Inā hele ka luaʻi ma nā kahe o ke koko, pāpā ʻia ka gastric lavage. I ka wā e hiki mai ana, ua kuhikuhi ʻia ka lāʻau lapaʻau, e kuhikuhi ana i ka mālama ʻana i ke koko maʻamau a me ka hana hanu. No nā hopu, mālama ʻia ʻo diazepam.
Nā ʻōlelo kikoʻī
I ka wā o ka papa hana, pono e mālama i ke kaʻi koko. No nā poʻe maʻi me ka hoʻokahe koko haʻahaʻa a paʻa ʻole, pono e hoʻemi ʻia ka ʻona.
Ma ke kauʻana o kahi o ka hanu koʻikoʻi, ʻoi aku ka hoʻomaʻamaʻa ʻia o ka mālama ʻana ma lalo o ka mākaʻina kokoke o kahi kauka.
Inā he hemorrhage i loko o ka retina o ka maka, pono e hoʻohana ʻia ka hoʻohana ʻana o Wazonite.
ʻO ka mālama ʻana i nā ʻōnaehana no ka hematocrit a me ka hemoglobin e pono ai i ka mālama ʻana o nā maʻi i hōʻola hou ia.
Me ka hana like o nā anticoagulants a me ka vasonitis, nā mākaʻi o ka ʻōnaehana coagulation koko (me nā INR) pono ka nānā pono.
I ka mālamaʻana i nā maʻi me ka maʻi mellitus e lawe ana i nā lāʻau hypoglycemic, e koi ʻia ke hoʻoponopono ʻia, no ka mea i ka manawa hoʻokahi o ka hoʻokele ʻana o Wazonite i nā wai he nui ka mea e hoʻomohala ai i ka hanana o ka hypoglycemia.
Hiki i nā mea maʻi o nā mea maʻi ke koi i ka hōʻemi ʻeha, ma muli o ka hoʻohaʻahaʻa ʻana i ka helu o ka hoʻopā a hoʻonui i hoʻonui ʻia bioavailability.
Ma ke ʻano o ka hoʻōla ʻana, ua ʻōlelo ʻia e pale ʻole i ka inu ʻawa.
Hiki i ke ulaula ke kōkua i ka hōʻemi ʻana i ka hopena therapeutic o Wazonite.
Ke hoʻokele nei i nā kaʻa a lawelawe i nā mīkini paʻakikī, pono e mālama ʻia ka mālama ʻana, no ka mea, ʻo ka hoʻohana ʻana i ka lāʻau hiki ke hōʻeha.
Hoʻohui nūhou
Hiki i ka Pentoxifylline ke hoʻoikaika i ka hopena o nā lāʻau lapaʻau e pili ana i ka ʻōnaehana coagulation o ke koko (thrombolytics, kūlike a pololei i ka anticoagulants), ka waila valproic, antibiotics (me ka cephalosporins - cefotetan, cefoperazone, cefamandol). Hoʻonui i ka pono o nā aelike hypoglycemic no ka hoʻokūkū waha, ka insulin a me nā mea hana antihypertensive.
Hoʻonui ʻo Cimetidine i ke kiʻekiʻe o ka pentoxifylline i loko o ke kō koko koko (ʻo ka hoʻomohala ʻana o nā hopena ʻaoʻao). ʻO ka hoʻohana pū ʻana o ka vasonite me nā xanthines ʻē aʻe hiki ke alakaʻi i ka hauʻoli. I kekahi o nā mea maʻi, ʻo ka hui pū ʻana o ka theophylline a me pentoxifylline e hiki ke hoʻonāukiuki i ka piʻi ʻana o ka theophylline concentration, kahi i piʻi ʻia ai ka nui o nā hopena o ka hopena e pili ana i ka theophylline.
ʻO nā hui o Wasonite e: Pentilin, Pentilin Forte, Pentoxifylline-Acre, Trental 400.
Nā Hōʻikeʻike e pili ana iā Wasonite
Hōʻikeʻike ʻikepili o Wazonite ma waena o nā mea maʻi. Ke hoʻohana ʻia nei i ka lāʻau i loko o ka hoʻopiko paʻakikī o nā maʻi āpau i mālama ʻia e nā maʻi lela peripheral, ʻike hou ʻia ka hoʻomaikaʻi ʻana i ke kūlana o nā mea maʻi. Eia nō naʻe, e hoʻomanaʻo ʻia he paʻakikī ʻo nā maʻi vascular āpau, ka mea e koi ai i ka hōʻola paʻakikī o lalo loa i lalo o ka mālama ʻana o kahi loea.
Aia kekahi hewa hewa maikaʻi e pili ana i ka lāʻau i pili i ka overdose a me nā hopena ʻaoʻao o ka pentoxifylline. No laila, ʻae ʻia ʻo Vasonitis e hana wale ma hope o ke koho ʻana i ke kauka, i mālama i nā ʻōuli a pau a me nā contraindications.
ʻO ka hopena Pharmacological
Hoʻomaikaʻi ʻo Vasonite i ka microcirculation a me nā ʻano rheological o ke koko, kahi hopena vasodilating. Loaʻa ka pentoxifylline, kahi derantative xanthine, ma ke ʻano he mea ikaika. Hoʻopili ka hana me ka hana i ka pale ʻana o ka phosphodiesterase a me ka hōʻiliʻili o ka cAMP i loko o nā palahalaha o nā aʻalima o nā poma o ke koko, i nā mea i hana ʻia o ke koko, i loko o nā ʻili a me nā kino āpau.
Mālama ka lāʻau lapaʻau i ka hoʻohui ʻana o nā platelets a me nā ʻāpana koko hoʻonaninani, hoʻonui i ko lākou elasticity, hōʻemi i ka pae o fibrinogen i loko o ka plasma koko a hoʻomaikaʻi i ka fibrinolysis, e hōʻemi ana i ka lapuwale o ke koko a hoʻomaikaʻi i kona waiwai rheological. Hoʻonui ia i ka hāʻawi ʻana i ka oxygen oxygen kiko i nā wahi o ka pōpilikia o ka maʻi, i ka nui o ke kino, ka palaka o ke kikowaena kikowaena, a, ma kahi liʻiliʻi, i loko o nā pūpū. Hoʻololi ʻili pono i nā moku coronary.
Nā hopena hopena
A ʻo ka loiloi o Wasonite, a ua ʻike nā kauka i nā hopena ʻokoʻa mai nā ʻōnaehana kino like ʻole, e like me:
- Mai ka ʻaoʻao o ka pūnaehana poinaka kikowaena: ka hōʻeha a me ka pohā, me ka hiamoe hoʻi o ka hiamoe, hopohopo, ʻoiai e like me nā ʻano e like me ka maʻi maʻamau.
- Mai ka hanu hana ʻana: nāi ʻana o ka momona, ka ʻeha, ka ʻōpū a me ka luaʻi ʻana, ka ʻeha ʻo epigastric, he ʻano o ka piha o ka ʻōpū.
- Mai nā pūnaehana ka hemopoietic a me ke koko: ka pehu i ka meile o ka mucous, ka ʻili, ka gastrointestinal tract, a me ka anemia aplastic, thrombocytopenia. ʻOiai e lawe ana iā Wasonite, pono ka mālama pinepine ʻana i ke ʻano koko.
- Mai ka pūnaehana cardiovascular: tachycardia, facial flushing, hoʻohaʻahaʻa i ke koko, ke angina pectoris, ka huhū ʻana o ka naʻau puʻuwai - e hele mai kēia mau hōʻailona me nā kiʻekiʻe kiʻekiʻe o ka lāʻau lapaʻau,
- He maʻi kūloko: nā hāmole o ka ʻili, kaʻeha, ka urticaria, kahi anaphylactic shock (loaʻa pinepine loa), ka edema Quincke.
ʻO ka lāʻau Vasonit - nā hopena hopena
He nui nā hopena o Vasonite mai nā kino ʻē aʻe a me nā ʻōnaehana.
Ma ka ʻōnaehana kikowaena waena - He maʻi kaumaha loa kēia, e pili ana i ka palupalu, ka ʻeha, ka hiamoe, a i ʻole ʻōpala, ʻāhewa ʻia, ka hihia o ka hoʻomohala ʻana meningitis. ^ E Ha yM. Hiki i ka popo ke hana i kahi pilikia i ka lawe ʻana i nā kaʻa, no laila i ka wā o ka mālama ʻana, ʻaʻole i kaomi.
Ma ka ʻōnaehana helehelena - hoʻonui puʻuwai puʻuwai, hōʻeha ka naʻau kaleha, puʻuwai naʻau (komo i ke ʻano o nā hopu ʻinalelo angina pectoris), kahi hōʻemi o ke koko (e koi a koʻikoʻi).
Mai ka manaʻo nui - ka hana hewa o ka ʻoniʻohi ʻike, nā nalowale o nā māla ʻike maka peripheral.
Ma ka gastrointestinal tract - kaomi i ka momona, ka malo maloʻo, nilo, hoʻopuka, ke nānā ʻana, me ka hoʻohuli ʻana me constipationʻeha a me ka ʻeha i loko o ka ʻōpū.
Ma ka akeo a me ka hāhai- ʻeha i ka hypochondrium pololei, ka neʻe ʻana o ka umauma, ka hoʻomaʻamaʻa ʻana i ke kaʻina a me nā ʻoi ʻana o ka hanana ʻōwili o ke aukile a me ke kīpī cholangitis a cholecystitis).
Mai ka pūnaehana koko - hoʻonui i ke kahe, koko mai nā ʻōpū kūloko, nā gums, nosebleeds, hōʻemi i nā pae koko o nā ʻōnaehana āpau, ma mua pā helu platelet a nā pili koko keʻokeʻo. ^ E Ha yM. Hiki nō ke kūkulu. anemia.
Ma ka ʻāpana o ka ʻili a me kāna mau kāpili- e kahe koko ana i ka ʻaoʻao kiʻekiʻe o ke kino a me ka maka, ke ʻoke ʻana, huina o nā papa manamana.
Hiki i nā lāʻau lapaʻau ke kumu nā pepeke, i hōʻike ʻia i loko o ke ʻano urticaria, Quincke edemaʻāwili paʻu a me ka ʻeha. Loaʻa paha ka hoʻomohala ʻana o ka hopena maʻi kūlohelohe i ke ʻano o ka anaphylactic pīhoihoi.
Vazonit - nā ʻōlelo aʻoaʻo no ka hoʻohana
Kuahi pua ua kauoha ʻia e lawe i kahi papa 600 mg ʻelua mau manawa ʻelua i ka lā ma hope o ka ʻaina, me ka ʻaʻa ʻole a me ka inu wai me ka wai.
No nā maʻi maʻi pilikino, ka koho ʻana o ka lāʻau, ʻo ka lōʻihi o ke lawe ʻana i nā papa i koho ʻia e ke kauka.
No laila, ʻo ka ʻōlelo no ka hoʻohana ʻana o Wazonite no ka mālamaʻana i nā mea maʻi me ka maʻi aho a me ka hana pāpaʻi, hōʻemi i ke koko haʻahaʻa a i ka wā ʻelemakule ua ʻōlelo e hōʻemi i ka ʻano maʻamau.
Hoʻohui ʻia o Wazonite me nā lāʻau lapaʻau ʻē aʻe
Pili ka lāʻau lapaʻau me nā mea lapaʻau he nui, hoʻonui ʻo ia i ka hana:
- nā lāʻau lapaʻau e keakea ana i ka hana o ke kaʻina hoʻokūkū o ke koko - pololei a kūlohelohe anticoagulants me nā mea ʻē aʻe
- nā maʻi maʻi mai ka hui cephalosporins(l. liwikuhia),
- ka momona valproic - ka lāʻau lapaʻau me ka hopena anticonvulsant,
- nā lāʻau lapaʻau e hoʻohaʻahaʻa i ke koko,
- nā lāʻau lapaʻau no ka mālama ʻana i ka maʻi maʻi.
Ke lawe ʻia me theophylline he hopena nui paha o nā mea hope.
Ke lawe ʻia me cimetidine aia nō ke kūlana he overdose o Wasonite.
Nā kikowaena o Wasonite
ʻO nā huahanaʻama nā mea lapaʻau o nā lāʻau lapaʻau like ʻole e hoʻohana ai e mālama i nā maʻi like. He analogue o Wasonite Xanthinol Nicotinate (Hoʻopau, Thiokol) - kahi mea lapaʻau i loaʻa ka hopena like ʻole, akā ʻokoʻa ka ʻano ikaika. Hoʻomaʻo ia i ka kaila koko peripheral (komo i ka kahe o ke koko ma ka wahi o ka lolo a me ka kiko o ka ʻike), hoʻonui i ka lawe a me ka assimilation o oxygen i nā kuli o ka lolo, hōʻemi pālepili ʻaila.
E hoʻokuʻu i ke ʻano, ka hoʻonohonoho ʻana o nā lāʻau
Hana ʻia Flowerpot i hoʻokahi kiʻi wale nō. Kālana lāʻau - nā papa hana lōʻihi. Ua uhi ʻia kēlā me kēia dragee i kahi kiʻi ʻoniʻoni, aia kahi ʻano oval i pale ʻia mai nā ʻaoʻao ʻelua. ʻO ka mea hana nui ʻo pentoxifylline.
Aia kēlā me kēia papa i ka 600 mg o ka lāʻau. ʻO ka hui pū ʻana o ka pūpili ka macrogol 6000, polyacrylic acid, titanium dioxide, talc. Hoʻopili ʻia nā papa i kahi palipona o 10 mau pākahi i kēlā Hoʻokomo ʻia ka flowerpot i ka pahu pahu pahu me kahi o ka annotation. Hoʻokahi i hoʻokahi pahu me 1-2 mau palaha.
Ke mīkini o ka hana, pharmacokinetics
Hoʻolālā ʻia ʻo Vasonite e hana maʻamau i ka microcirculatory, rheological waiwai o ke koko. Loaʻa kahi hopena vasodilating, angioprotective. ʻO Pentoxifylline, kekahi o nā derandava xanthine, e hana i ka mea nui. Mālama ka mea hana i ka phosphodiesterase, hoʻolaha i ka hōʻiliʻili o nā monophosphates cyclic.
Hoʻomaʻa ʻia ka lāʻau lapaʻau i ka hoʻopili ʻana o nā ʻāpana koko ʻaʻī, platelets, hoʻonui i kā lākou elasticity, hōʻemi i nā pae fibrinogen. Loaʻa ka Pentoxifylline i ka hopena e pili ana i nā moku coronary, hoʻihoʻi i ka halihali o nā oxygen i nā wahi me ka hana o ka neʻe ʻana o ka maʻi. Hoʻohana maikaʻi i ka pūnaehana neʻe, ka laha o ka cerebral, i kahi liʻiliʻi ma luna o nā pūpū.
He ʻoihana ka Pentoxifylline i ka nalowale o nā moku peripheral, hoʻopau i nā pōpoki pō, a he hōʻemi i ka nui o ka ʻeha. ʻO nā ʻōkuhi no ka lāʻau lapaʻau e wehewehe pū i ka hopena myotropic, vasodilating.
Hiki i ka hopena therapeutic ke lōʻihi i ka 12 hola.
Me ka hoʻokolohua waha o Wazonite, ʻo ka mea hana e kokoke ana iā 100% i hoʻoulu ʻia mai ka gastrointestinal system. He hopena lōʻihi ka ʻoi aku, aʻo ka mea hana i hoʻokuʻu mau ʻia, a laila hoʻihoʻi ʻia. ʻO ka nui loa o ka lāʻau i ke koko ma hope o ka hoʻokele ʻana ma hope o 3-4 mau hola. Hoʻopau loa ʻia ka lāʻau lapaʻau aneane e nā keiki. Ua hoʻopaʻa ʻia ka excretion me ka waiū umauma.
Hoʻohui lehulehu
Wahi a ka annotation, lawe ʻia ʻo Vasonite ma ke alo o kahi kīʻaha, me ka wā ʻole, ka holoi ʻia ʻana me ka nui o ka nui o ka wai. ʻO ka pākaukau maʻamau he 1 600 mg papa i ke kakahiaka a me nā hola ahiahi. ʻO ka palena kiʻekiʻe loa i kēlā me kēia lā he 1200 mg. ʻO ka lōʻihi o ke ala therapeutic i kuhikuhi ʻia e ke kauka ma muli o ka nui o ka maʻi, ka kiʻi haukapila o ka maʻi.
I loko o nā hōʻeha i nā mea maʻi me ka hōʻeha koʻikoʻi i ka palapaleka a me nā puʻupaʻa, e hōʻemi ʻia ka hōʻemi i ke ʻano maʻamau no ka hoʻomanawanui ʻana o ka lāʻau. Inā emi mai ka cleince cleinine ma mua o 30 ml / min, ʻaʻole hiki ke keu aku i ka nui o ka ʻawaʻawa no ke kī ʻana i ka 600 mg. I ka mālamaʻana i nā mea maʻi me ka hoʻokahe koko haʻahaʻa, hoʻomaka ke papa lāʻau e hoʻomaka me nā dosis liʻiliʻi (150-300 mg), e holomua ana, ʻoiai e nānā ana i nā hōʻailona.
Nā lāʻau like ʻole
Inā hiki ʻole ke hoʻohana iā Wazonit, hiki nō ke kuhikuhi i nā lāʻau lapaʻau ʻē aʻe e like me ka hana. ʻOi aku kekahi mau analogues ma mua o ka lāʻau i ho'ākāka ʻia, no laila e makemake nā mea maʻi e koho iā lākou.
Ke poʻo inoa | Nā mea waiwai | Mea hana | ʻO ke kumukūʻai ma nā rubles |
Kauhi Kahele | palekezila | Laia LLC | 300-400 |
Cinnarizine | cinnarizine | BALKANPHARMA-DUPNITSA AD | 30-50 |
Kauhi | palʻaihopezila | Sanofi aventis | 150-200 |
ʻO Agapurin | palʻaihopezila | Zenithiva | 200-300 |
Hiki i nā lāʻau lapaʻau i kapa ʻia i ke ʻano o nā hoʻonā i hiki ke hoʻopaʻa ʻia. I nā hihia therapeutic koʻikoʻi, ʻoi aku ka maikaʻi o ke koho ʻana i nā ʻōlelo lapaʻau, ʻoiai ua ʻike ʻia ka pau ʻana o ka lāʻau lapaʻau me ka ʻoi aku ka maikaʻi.
ʻLoe a me ke kākele
Mai nā ʻōlelo ʻōlelo iā Wazonit, ʻike maopopo ʻoe e pono ka ʻai ʻana i ka lāʻau ma hope o ka ʻai ʻana, me ka ʻaika ʻole ʻana a inu ʻole i ka wai inu ʻokoʻa. I ka hapanui pinepine, hoʻoholo ke kauka i ka ʻeha a me ka lōʻihi o ka mālama ʻana i ka mōʻaukala, ʻano a me ke ʻano o ka maʻi. Akā, ka mea maʻamau, ʻo ka papaʻa ka nui maʻa papa he 1 papa ʻelua i ka lā.
ʻO ka dosage nui loa he 1,2 g i kēlā me kēia lā.
Nā ʻōkuhi no ka hoʻohana ʻana iā Vazonit 600 mg, dosis
Pono e mālama ʻia nā papa liʻiliʻi, me ka ʻole o ka ʻamaʻa a me ka inu ʻana i nā ʻano wai nui, ʻoi aku ka maikaʻi ma hope o ka ʻaina.
ʻO nā hewa dosage, e like me nā kauoha no ka hoʻohana ʻana iā Vazonit - 1 papa o Vazonit 600 mg 2 mau lā i ka lā. ʻO ka palena loa i kēlā me kēia lā he 1200 mg (2 papa).
Hoʻoholo ʻia ka lōʻihi o ka mālama ʻana a me ka hoʻoponopono ʻia ʻana e ka kauka e like me ke kiʻi o nā maʻi ʻo ka maʻi a me ka hopena therapeutic i loaʻa.
Hoike waiwai
I ka poʻe maʻi me ka pīhaʻi hana koʻikoʻi o ke ake, pono ke hoʻemi ʻia ʻana o ka laʻana i ka mālama ʻana i ke ahonui.
ʻO ka mālama ʻana o nā mea maʻi me ka hoʻokahe koko haʻahaʻa, me nā mea maʻi e hōʻemi ʻia ma muli o kahi hiki ke emi i ke kahe o ke koko (hemodynamically koʻikoʻi stenosis o ka moku cerebral, i kahi ʻano koʻikoʻi o ka maʻi naʻau coronary), ua manaʻo ʻia e hoʻomaka me nā dosis liʻiliʻi. I kēia mau hihia, ʻae ʻia kahi piʻi liʻiliʻi o ka hala.
I nā maʻi me nā maʻi renal ʻole (CC ma mua o 30 ml / min), hoʻemi ʻia ka nui o kēlā me kēia lā i 600 mg.
ʻOnymslelo like o Wasonite
Nui kekahi mau ʻonymslelo like o Wazonite, ʻo ia hoʻi nā lāʻau lapaʻau e hoʻohana ai i ka pisaxifylline. Puka ʻĀina, ʻO AgapurinKauhi, Latren, Pentoxifylline me nā mea ʻē aʻe
ʻO nā mea o nā vasonite, ke kumukūʻai i nā lāʻau lapaʻau
Inā pono, hiki iā ʻoe ke hoʻololi i ka Vasonite me ka analogue o ka mea ikaika - eia nā mau lāʻau lapaʻau.
Ke koho ʻana i nā mea kikoʻī, pono e hoʻomaopopo i nā ʻōlelo aʻo no ka hoʻohana ʻana iā Vazonit 600 mg, ke kumukūʻai a me nā loiloi o nā lāʻau lapaʻau me nā hopena like ʻole. He mea nui ia e kamaʻilio pū me ke kauka kauka a ʻaʻole hoʻi e hana i kahi loli kūʻokoʻa kūʻokoʻa.
ʻO ke kumukūʻai i nā lāʻau lapaʻau o Lūkia: Vazonit 600 mg aʻa ʻoki 20 papa - mai 393 a 472 mau rubles, e like me 582 mau lāʻau lapaʻau.
ʻO 5 mau makahiki kahi ola. E kūʻai ma ke ʻano wela i ka 25 ° C ma kahi maloʻo a pouli hoʻi a hiki i ka hiki ʻole o nā keiki. ʻO nā kūlana o ka hāʻawi ʻana mai i nā lāʻau lapaʻau ma o ke kau ʻana.
He aha ka ʻōlelo o nā loiloi?
ʻO ka hapa nui o nā loiloi he kūpono, me ka hoʻopuka ʻana o nā papa Vazonit i ka mālama ʻana i nā maʻi like ʻole me nā maʻi lele peripheral, e holomua ana ka nohona o nā mea maʻi. Akā paʻakikī nā maʻi vascular āpau e hoʻomaʻamaʻa a koi aku i nā lāʻau paʻakikī ʻana loa i lalo o ka mālama ʻana o kekahi kauka.
ʻO nā loiloi maikaʻi e pili ana i ka Wazonit 600 mg e pili ana i nā hopena ʻaoʻao a me kahi overdose o ka lāʻau. ʻO ia ke kumu e kuhikuhi ʻia e ke kauka, i ka ʻike ʻana i nā hōʻailona a me nā contraindications.
2 loiloi no ka "Wazonite 600 mg"
Mākou i kūʻai i kēia mau paila no ka pule i hala. Ua loaʻa iā ia kahi kī nui loa me ka maʻi pālima lima. Ua hoʻi hou lākou mai ka haukapila me kahi papa lāʻau no kēia lāʻau lapaʻau, ke kali nei mākou e hana. I kēia manawa, ʻaʻole ʻike ʻia kekahi mau hopena.
ʻO ka pentoxifylline ka mea maʻalahi ma mua o nā analogues a me kahi like me ka inoa ʻē aʻe