Biosulin® P (Biosulin R)

ʻO Biosulin P kahi lāʻau lapaʻau ia e hoʻohālikelike i ka insulin endogenous hana pōkole o ke kanaka. Loaʻa kēia insulin i ka ʻenehana genetic, ma muli o kēia, e like me ka helu, ʻo Biosulin P ka mea i hui pū ʻia e nā insulins loea kanaka.

Hoʻomaka ka hoʻomaka ʻana o ka hana ma hope o 30-60 mau minuke a nānā ʻia no nā hola 6-8.

ʻIke ʻia nā ʻonikela Insulin ma loko o ke kino no ka mea e pili ana ia i nā hana metabolic āpau a hoʻihoʻi i ka nui o nā hopena intracellular. Akā ʻo nā kumu nui no ka insulin ka ate, nā ʻāpana a me nā kiko adipose. Nā hopena biological o ka insulin:

• hoʻoponopono i ka hoʻoneʻeʻana o nā minamina o ka paʻakai ka hopena o ka hoʻonui i ka lawe a me ka hoʻohana ʻana i nā glucose i nā pupu, ma muli o ka hana glycogen ate.
• ka pale ʻana o ka hoʻoliʻiliʻi glucose kūlohelohe ma muli o ke kaohi ʻana o ka wāʻi i ka leʻaleʻa o ka glycogen a me ka hoʻohaʻahaʻa ʻana i ka hana o ka glucose mai nā kumu e ae,
• komo i ka metabolism o nā momona, i hōʻike ʻia e ka hoʻokaʻa ʻana i kā lākou mau momona, hiki i ka hoʻēmi ʻana i ka waihona loko o nā momona momona i loko o ke koko,
• ālai ʻia i ka hana ʻana o ke ketones,
• mahuahua ka hana o nā momona momona me kā lākou esterification ma hope, no ka mea i hoʻokumu ʻia ai kahi coenzyme koʻikoʻi i loko o ke kino,
• komo i ka protein proteinism, ka mea e hoʻonui ai i ka lawe ʻana i nā waʻa amino amino i loko o nā ʻōpū, ka hoʻowalewale ʻana i ka hoʻouka ʻana o nā peptides, hōʻemi ʻia ka ʻai ʻana o nā protein e nā kopa, a me ka hoʻohiolo ʻana i ka hoʻokumu ʻana o nā waila keto mai nā waikawa amino.
• hoʻolaʻa a pale ʻole i nā ʻano ʻano like ʻole o ke ʻano.

ʻO nā Insulins ke ala kumu no ka hoʻololi hou ʻana i ka maʻi lapaʻau. Ke kau nei ka koho o ka lāʻau lapaʻau ma muli o ka hōʻino a me nā ʻano o ka hele o ka maʻi, ka kūlana o ka mea maʻi a me ka wikiwiki a me ka lōʻihi o ka hopena hypoglycemic. Hoʻopili ʻia ka mālama ʻia e like me nā hana pilikino, kahi e hui ʻia ai ka hoʻomākaukau ʻana i ka insulin o nā ʻano like ʻole o ka hana.

ʻO ka hoʻoponopono ʻai ʻia i ka wā e hoʻohana ai i ka insulin e pono e kaupalena ʻia e ka waiwai ikaika o ka meaʻai mai 1700 a 3000 kcal.

Ke koho ʻana i kahi kūpono, ʻike ʻia ke kō o ke koko a me ka wai i loko o kahi ʻōpū ʻole a i ke ao. ʻO ka hoʻoholo hope loa e kau nei i kahi hoʻoemi i ka hyperglycemia, glycosuria, i pili i ka mālama pono o ka mea maʻi.

ʻO Biosulin P ka hoʻokele pinepine ʻana i nā subcutaneously, ʻokoʻa pinepine - intramuscularly. ʻO ka hoʻopili ʻana a me ka manawa e hoʻomohala ai i ka hopena, ʻaʻole wale i ka ala o ka hoʻokele, akā, ma ka wahi nō hoʻi, ka nui a me ka hoʻoliʻi o ka insulin.

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa ka Biosulin P ma ke ala no ka injection me ka dosage o 100 U / 1 ml. Loko paha ka pahu i ka 5 ml a i ʻole 10 ml, 1, 2, 3 a i ʻole 5 mau ʻāpana i kēlā me kēia ʻeke. ʻO ka mea hana i ka lāʻau lapaʻauʻo Marvel LifeSciences (India).

Aia i ka:

• soluble insulin - 100 mg,
• nā mea kikoʻī ʻē aʻe.

Na ka lāʻau lapaʻau ia ma o ka ʻāpana o nā insulins i hoʻohana ʻia no ka hana hoʻohalike, e haku ʻia e ka ʻano ʻenehana genetic, a ua kau ʻia ma ke ʻano.

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana

ma nā pahu he 10 ml, i loko o kahi ʻeke pepa 1 pahu a i ʻole i nā pahu pahu o 3 ml, i loko o ka pā i kuhi ʻia 5 mau p.

Nā hōʻailona no ka hoʻohana ʻana

• ʻO mellitus ka pakanika o ke insulin (type I),
• non-insulin type-dependence of diabetes mellitus (type II) with the development of resistence to oral hypoglycemic drug,
• non-insulin type-dependence of diabetes mellitus (type II) with the development of partial resistance to oral hypoglycemic drug inā ke kuhikuhi ʻana i ka hoʻōla hui ʻia,
• nā maʻi hakakā (nā maʻi ʻeha e hoʻopiha i ka papa o ka maʻi mellitus o kēlā me kēia ʻano).
• decompensation o nā pākia hana, ke kumu kahi e ulia ai ka poʻe me ka maʻi maʻi.

Eia kekahi, e like me ka mea i kuhikuhi ʻia e ke kauka, hiki i nā mea he insulins ke hoʻohana ʻia i kēlā mau hihia:

• i ka hoʻomākaukau ʻana no nā kaʻina hana ma nā maʻi me nā maʻi II o ke ʻano,
• me ka hānai me nā wahine hāpai,
• ʻoiai he lāʻau lapaʻau lāʻau e hoʻopau ai i ka momona nui,
• me ka hulu manu o,
• me ka hyperthyroidism,
• me ka atony a i ʻole ptosis o ka ʻōpū,
• i nā mākaʻi o ka hepatitis,
• me ka cirrhosis o ka ate i ka hoʻomaka ʻana o ka maʻi.
• ma kahi kūlana o coma hypoglycemic,
• ma ke ʻano o ka mālama ʻana i ka hopena o ka naʻau paʻakikī.

Nā Hoʻohui

ʻO Biosulin P kahi i hoʻohālikelike ʻia:

• me ka ulu ʻana o ka naʻau i nā mea ikaika a me nā mea ʻē aʻe o ka lāʻau lapaʻau,
• me kahi kūlana hypoglycemic o kekahi kumu,
• i nā maʻi hepatic nui, pancreatic, nā maʻi ʻula,
• me ka uluna peptic o ka ʻeha gastrointestinal,
• me nā puʻuwai naʻau i ke kahua o ka decompensation,
• me ka loaʻa ʻole o ka naʻau coronary.

Ke ʻano o ka noi

Hoʻōla ʻia ka lāʻau lāʻau 30 mau minuke ma mua o kahi pāʻina. Koho ʻia ka nui o ka pauku e ke kauka.

ʻO ka nui awelika o kēlā me kēia lā mai ka 0.5 a 1 IU i hoʻokahi kilogram o ka paona maʻi.

Ke hoʻohana nei i Biosulin P ma ke ʻano he lāʻau lapaʻau hoʻokahi, e lawelawe ʻia ʻo 3 manawa / lā a i ʻole e hoʻonui ʻia i ka manawa 5-6 inā pono. Ma kahi o ka wai o ka nui o ka 0.6 IU / kg i kēlā me kēia lā, pono ia e hoʻohana i kēlā me kēia mau wahi i ke ʻano o 2 a i ʻole nā ​​mea inikini.

ʻO ka pūnaewele wana e hāhā pinepine ʻia ʻo Biosulin P ʻo ia ka paia o ka ʻōpū, akā hiki ke hoʻohana ʻia i nā ʻūhā, nā ʻūhā, a me nā poʻohiwi hoʻi. I mea e pale ai i ka hoʻomohala ʻana o ka dystrophy tissue adipose ma ka wahi i hoʻopaʻa ʻia, pono e hoʻololi ʻia ka pūnaewele injection.

Ke lawe ʻia nei ka hoʻokele Intramuscular a me ka intravenous ma lalo o ka nānā ʻana o kahi kauka.

Penei ka hoʻomaka ʻana:

• me nā manamana lima ʻelua he ʻili ʻōwili.
• ua hoʻokomo ʻia ka pūpū i loko o kona waihona i ke kihi o 45 degere,
• civutaneusly drive a no ka hoʻokō piha, hoʻopaʻa i ka pono no kekahi mau kekona ma lalo o ka ʻili, a laila e hoʻoneʻe.

Inā ua puka mai ke koko ma kahi o nā injection, e kaomi iki me kou manamana lima a paʻa.

Nā hopena hopena

• hypoglycemia, ka mea i hōʻike ʻia e ka pallor, nā mea he nui, ka tachycardia, nā kuʻekuʻe ʻana, nā mea kikowaena, ka ʻai ʻana. Hoʻonui ka hypoglycemia i ka comog hypoglycemic.
• ʻulaʻula, kala a wīwī i ke kahua o ka ʻōlelo loiloi,
• adipose tissue dystrophy i ka wā i lawelawe ʻia ma kahi hoʻokahi,
• ke ʻano o ka hypersensitivity ma ke ʻano o ka rashes, ka edema o Quincke, anaphylaxis hiki ke loaʻa pinepine ʻole,
• ka humuhumu a ʻike 'ole paha i ka hana mua o ka hoʻohana.

Hiki i nā kumu no ka hoʻomohala ʻana i ke kūlana hypoglycemic i loko:

• overdose o kahi mea waiwai
• hoʻōla lāʻau
• nele i ka ʻai ʻana ma ka ʻai ʻana ma ke ʻano o ka ʻai ʻana,
• puaau, huʻi,
• hoonui kino,
• nā maʻi e loaʻa ai ka emi ʻana o ke koina o ke kino no ka hemo, e like me ke ʻano o nā palola o nā aʻalā a i ʻole nā ​​ʻili, kahi i hoʻoneʻe ʻia o ka hana hana o ke kūloko adrenal, pituitary a i ʻole thyroid gland.
• kūleʻa me nā lāʻau ʻē aʻe.

Nā ʻōlelo kikoʻī

• i ka loli ke kala o ka hoʻonā, ke ʻano o ka turbidity a i ʻole pālua, hoʻohana hou ka hoʻohana ʻana.
• i ka wā o ka papa hana me ka hoʻomākaukau ʻana o ka insulin, pono e kiaʻi mau i ka nui o ka glucose i ke koko,
• me nā wā lōʻihi i waena o ka hoʻopuka a hoʻohana ʻana paha i ka hewa hewa, hiki ke hoʻomohala ʻia ka hoʻomohala ʻana o ka hyperglycemia, ka mea i hōʻike ʻia e ka make ʻole o ka makewai, ka hoʻolau pinepine ʻana, ka nausea a me ka luaʻi ʻana, ke ʻano o ka ʻula a me ka maloʻo ʻana o ka ʻili, kahi hōʻemi i ka momona a me ka honi o ka acetone mai ka mea maʻi. I ka haʻalele ʻana o ka lāʻau no kēia ʻano, hiki i ka hiki ke hoʻomohala i ka ketoacidosis, kahi e hoʻoweliweli ʻia ana ke ola.
• me ka hoʻonui ʻana o ke kino pilikino, nā maʻi, ka maʻi, nā maʻi o ka thyroid gland, ate, nā pēpē a me nā ala ʻē aʻe, a ʻoi aku ma luna o ka makahiki 65 a me ka hoʻololi ʻana i ka meaʻai, pono ke hoʻoponopono ʻia ka nui o ka lāʻau.
• hiki i kekahi mau maʻi ke hoʻonui i ka pono no ka insulin (no ka laʻana, nā ʻano like ʻole i ke ʻano maʻi kiʻekiʻe).
• ke hoʻololi nei i ka lāʻau lapaʻau, pono ke nānā i ke kahe o ke koko.
• ʻO ka Biosulin P e hōʻemi i ka laweʻana o ka waiʻona,
• ʻaʻole pono ʻia ka hoʻohana ʻana o nā poma i ka insulin no ka mea hiki ke hoʻololi i ka lāʻau i loko o catheters.
• Me nā loli like ʻole e pili ana i ka therapy insulin, kahi i hoʻemi ʻia i ka hiki ke hana ʻana a i ʻole ka hana o ka hana e koi ai ka nui o ka makaʻala.

Hoʻohui nūhou

• mahuahua ka hopena o ka hoʻohaʻahaʻa ʻana i ke kō o Biosulin P e nānā ana i ka wā e lawe ai: nā papa o nā lāʻau hoʻohaʻahaʻa i ke kō, nā lāʻau antidepressants, lipid-lowing, antihypertensive a me ka diuretic lāʻau, bromocriptine, octreotide, sulfanilamide a tetracycline antibiotics, steroid anabolic drug, ketoconofolamine, phenol cyclofenolamine, ke kumu o ka lithium, nā mea inu waiʻona.
• ka hopena o ka hopena o ka hypoglycemic hopena i ka wā e lawe ai i ka ʻohiʻokeʻo hormonal, glucocorticosteroids, heʻano thyroid, kekahi diuretics a me antidepressants, heparin, ulana simpathomimetic, danazole, clonidine, antihypertensive lāʻau lapaʻau, diazoxide, narcotic analgesics, nikotine.
• E hoʻonāwaliwali nā Reserpine i ka hana a Biosulin R.

ʻO nā inoa o Biosulin P kahi mea hana lima pōkole e like me lākou:

• Loaʻa ka Actrapid NM i nā pahu wai 10 ml. Mea Hana: Novo Nordisk (Denemaka). Loaʻa ka Actrapid NM Penfill mai nā mea hana like i ka pahu pahu 3 ml no ka penfill. Aia he 5 mau pākeke i pākaʻi,
• Hele mai hoʻi ʻo Vosulim-R i ke ʻano o nā pahu loiloi a me nā pākuʻi, hana ʻia e Wockhardt Limited (India),
• Gensulin R o nā huahana hale, nā ʻoihana ʻenehana: Bioton Vostok ZAO (Rusia),
• Insuman Rapid GT, Aventis Pharma Deutschland GmbH (Kelemānia),
• Hoʻokumu ʻia ʻo Insuran R e ka Institute of Bioorganic Chemistry. Na Luna Wahine M.M.Shemyakin ame Yu.A. Ovchinnikov RAS (Russia),
• Monoinsulin CR, ʻO Belmedpreparaty RUE (Republic of Belarus),
• Rinsulin R, GEROFARM-Bio OJSC (Rūsia),
• Rosinsulin R, Medsintez Plant (Rūsia),
• Humulin maʻamau, Lilly Farani (Palani).

Lapaʻau lāʻau

He ia huina kanaka i loaʻa me ka ʻenehana DNA recombinant.

Hoʻopili pū kekahi me kahi receptor kūikawā ma ka membone cytoplasmic o waho o nā pūpū a hana i kahi mea hoʻohui insulin-receptor e hoʻoikaika i nā hanana intracellular, e komo synthesis o kekahi o nā kīʻaha koʻikoʻi (hexokinase, pyruvate kinase, glycogen synthetase). ʻO ka hoʻohaʻahaʻa o ka glucose i ke koko ma muli o ka hoʻonui i loko o kāna kaomi intracellular, hoʻonui i ke kūoʻi ʻana a me ka assimilation o nā ʻiʻo, hoʻoulu ʻana i nā lipogenesis, glycogenogenesis, a me kahi ka emi o ka hōʻemi o ka hana glucose i ka ate.

ʻO ka lōʻihi o ka hana o ka hoʻomākaukau ʻana o ka insulin no ka nui o ka absorption, ka mea e hilinai ana i nā mea he nui (no ka laʻana, ka hoʻohālikelike, ke ʻano a me nā wahi o ka hoʻokele), a no laila ua pili ʻia ka ʻike o ka insulin e pili ana i nā loli nui, i nā kānaka like ʻole a me ka mea like i ka mea like . ^ E Ha yM.

Ma hope o ka hoʻomalu sc, ua hoʻomaka ka hoʻomaka ʻana o nā hana a ka lāʻau ma hope o 30 mau minuke, ka hopena o ka hopena loa ma waena o 2 a me 4 mau hola, ʻo 6-8 ka lōʻihi o ka hana.

Lapaʻau lāʻau

ʻO ka piha piha o ka ʻono a me ka hoʻomaka ʻana o ka hopena o ka insulin e hilinaʻi ana i ke ala o ka hoʻokele (sc or intramuscularly) a me kahi o ka hoʻokele (ʻūhā, ʻūhā, ʻūhā), ka waiʻu (nui o nā inikua i huehue ʻia), a me ka ʻike ʻana o ka insulin i ka hoʻomākaukau.

E kahele ʻia ʻokoʻa ma nā kiko. ʻAʻole ia e hele i ka pale o ka placental a ʻaʻole i hoʻopā ʻia i ka waiū umauma.

Ua luku ʻia ia e ka insulinase ma ka nui a me nā kau.

T_1/2 - He mau minuke. Kūpono ʻia i ka urine - 30-80%.

Nā hōʻikeʻike o ka lāʻau Biosulin ® R

ʻano hika type 1

type 2 diabetes mellitus (non-insulin-dependant): pae kū'ē i ka waha hypoglycemic agents, ka pale ʻana i ka paleʻana i kēia mau lāʻau (i ka wā hui pū ʻana), nā maʻi kūlohelohe,

nā pilikia olakino i ka mea maʻi me ka maʻi mellitus, i ukali ʻia me ka hoʻokaʻawale o nā pakanā kiola.

Hoʻohui

Nui kekahi mau lāʻau lapaʻau e pili pono ana i ka pono o ka insulin.

Hypoglycemic hopena o ka insulina ka hōʻoi 'ku una ha hypoglycemic ai', Mao nā mea kūpale, ACE nā mea kūpale, carbonic anhydrase nā mea kūpale, e wae Hoʻokolohua-blockers, bromocriptine, octreotide, sulfonamides, anabolic steroid, tetracyclines, clofibrate, ketoconazole, mebendazole, pyridoxine, cyclophosphamide, fenfluramine, likiuma, ai ', pili ka ethanol.

Contraceptives oral, corticosteroids, thyroid hormone, thiazide diuretics, heparin, tricyclic antidepressants, sympathomimetics, danazole, clonidine, BKK, diazoxide, morphine, phenytoin, nicotine nawaliwali i ka hopena hypoglycemic o ka insulin.

Ma lalo o ke kiʻi o ka reserpine a me salicylates, hiki ke nawaliwali a me ke hoʻonui ʻana i ka hana o ka lāʻau lapaʻau.

Ke keu

Nā Hoʻomaka Hoʻokumu paha ka hypoglycemia.

Lāʻau: hiki i ka mea maʻi ke hōʻoki i ka hypoglycemia palu ma ka lawe ʻana i ke kōpaʻa aʻai ʻole nā ​​mea ʻai i ka haʻalulu. No laila, ua makemake ʻia no nā maʻi me ka maʻi diabetes e lawe i ka kō, nā wai momona a i ʻole nā ​​mea momona ʻē aʻe me lākou.

Ma nā pilikia koʻikoʻi, i ka wā e nalowale ai ka mea maʻi, ʻike ka hopena o 40 dextrose e ka iv, i / m, s / c, iv glucagon. Ma hope o ka loaʻa hou ʻana i ka ʻike, ʻike ʻia ka mea maʻi e ʻai i nā meaʻai momona a keu e pale ai i ka hoʻomohala ʻana o ka hypoglycemia.

E hoʻokuʻu i nā palapala a me ka ʻano

Kūkā ʻia ka hoʻonāʻau ʻia ma ke ʻano he wai kūlike ka waihoʻoluʻu. E like me ka mea e hoʻopili ikaika ai, 1 ml o ke kaʻaila i loaʻa iā 100 IU o ke aniani i hoʻokahe ʻia i loko o insin. E hoʻoponopono i ka pH o ka wai e hoʻonui i ka bioavailability, ua hoʻonui ʻia ka mea hana me nā ʻōlelo i lalo:

• metacresol
• wai wai
• ʻOi i ka 10% epaa kōpaʻa,
• kahi hopena o ka hoʻoneʻe hydrochloric o 10% kaulike.

Loaʻa nā Biosulin i nā hue wai a i ʻole nā ​​pahu pahu me kahi hapa 3 ml, i hana pono ʻia no ke hoʻohana pono ʻana me nā syringe ʻo Biomatic Pen. ʻO ka pūpū pepa pahu i loaʻa nā waihona 5 i loko o kahi pale polū palaka.

Ka hana lāʻau lapaʻau

Ke hahai nei ʻo Insulin i ke ʻano o ka hormone pancreatic kanaka ma o ka recombination DNA. ʻO ka hopena hypoglycemic ma muli o ke kaohi ʻana o ka mea hana i nā mea ʻala e hoʻāʻo ai i ka ʻaoʻao waho o ka membrane keola. Mahalo i kēia pūhui, ua haku ʻia kahi pūpū o nā pū me ka insulin, e hoʻonui ai i ka hana o ka enzymatic o ka hexose-6-phosphotransferase, ka ate glycogen synthesis a me ka hoʻohaʻahaʻa glucose. A ke hopena, ʻike ʻia kahi emi o ka hoʻoliʻiliʻi o ka hoʻokahe koko serum.

Hoʻonui ka Biosulin P i ka hoʻokumuʻana o ka glycogen a me nā momona momona mai ka glucose, e hoʻolohi ana i nā kaʻina hana o ka gluconeogenesis i loko o ka ate.

Loaʻa ka hopena therapeutic e ka hoʻonui ʻana i ke kōpae ʻana o ke kō i nā kō. Hoʻohui ʻia kona halihali i loko o nā pū. Hoʻohui ka hana ʻana o ka glycogen a me nā momona momona mai ka glucose, a e emi ka hana a nā gluconeogenesis ma loko o ka puʻuwai.

Hoʻonā ʻia ka lōʻihi o ka hopena hypoglycemic pili i ka helu o ka assimilation, ka mea, ma ka huli ʻana, e hilinaʻi nei i ka wahi a me ke ʻano o ka lawelawe ʻana o ka insulin, ka ʻano pilikino o ka maʻi maʻi. Ma hope o ka lawelawe subutanutan, ua nānā ʻia ka hopena therapeutic ma hope o ka hapalua hola a hiki i ke kiʻekiʻe loa ma waena o 3 a 4 mau hola ma hope o ka hoʻohana ʻana i ka pahu lāʻau. Loaʻa ka hopena hypoglycemic no 6-8 mau hola.

Bioavailability a me ka hoʻomaka ʻana o ka hana therapeutic i hilinaʻi i kēia mau mea:

• ke ʻano o ka palapala noi - ʻae ʻia ka subcutaneous a i ʻole intramuscular injection,
• ka nui o ka hoʻokele no ka hormone
• site injection (rectus abdominis, anterior thigh, gluteus maximus),
• kūlohelohe insulin.

Ka māhele hānai ʻia ʻana o ka hormone synthesized ma ke kino. Ua luku ʻia ka wahi ʻoihana a me nā maʻi hepatocytes a me nā paʻi. ʻO ka hapalua-ola he 5-10 mau minuke. Ke waiho nei ka mea kanu kino i ke kino ma ka 30-80% me ka urine.

He hopena pōkole ʻo Insulin.

Hoʻohālikelike ka lōʻihi o ka hopena hypoglycemic pili i ka helu o ka assimilation.

Pehea e lawe ai iā Biosulin P

Hoʻoholo ʻia ka nui o ka inehina e kekahi kauka olakino ma kahi kanaka hoʻokahi, ma muli o nā hōʻailona o ke kō koko koko. Hoʻolālā ʻia ʻo Biosulin e lawelawe ʻia i ka subcutaneously, ma nā wahi me kahi papa o nā ʻōpū hohonu a me ka intravenously. ʻO ka helu ʻai ma kēlā me kēia lā he 0.5-1 IU i ka 1 kg o ka paona (e pili ana i 30-40 mau hui).

Kūloko nā kauka lapaʻau e lawelawe i ka lāʻau lapaʻau i nā minuke 30 ma mua o ka hoʻomaka ʻana o ka waiwai o ka ʻai. I kēia hihia, pono ke ʻano like o ka mahana o ka lāʻau lapaʻau me ka mahana ambient. Me ka monotherapy me Biosulin, mālama ʻia kahi lawelawe hypoglycemic 3 mau manawa i ka lā, i mua o nā kīmaha ma waena o nā meaʻai, ka piʻi ʻana o ka nui o nā inikina i mau manawa he 5-6. Inā ʻoi aku ka dosage i ka 0.6 IU i ka 1 kg o ka paona o ke kino, pono ia e hana i 2 injections ma nā ʻāpana like ʻole o ke kino ʻaʻole i kahi o hoʻokahi anatomical pae.

Pono e kuhi i nā lāʻau lapaʻau ma lalo o ka ʻili ma luna o nā ʻōpū o nā abdominisus rectus, e ukali ana i ka algorithm ulu o nā hana:

1. Ma ka pūnaewele o ka hoʻomaka ʻana, pono ʻoe e hōʻiliʻili i ka ʻili i loko o kahi kui e hoʻohana ana i ka manamana lima a me ke kīlohelohe. Pono e hoʻokomo pono i ka lāʻau hoʻoneʻe i ka ʻili o ka ʻili ma ke kihi o 45 ° a hoʻēmi ʻia ka piston.
2. Ma hope o ka hoʻopuka ʻana i ka insulin, pono ʻoe e haʻalele i ka pono ma lalo o ka ʻili no ka 6 a i ʻole mau kekona e hōʻike ai i ka hoʻokō piha ʻana o ka lāʻau.
3. Ma hope o ka wehe ʻana i ka pūkaʻu, hiki mai ke koko ma ke kahua hōʻike. Pono e paʻi ʻia ka wahi i hele ʻia me ka wīwī a i ʻole nā ​​ʻāpana hulu i ka hoʻohuihui ʻia.

Eia kekahi, pono e loaʻa i kēlā me kēia maʻi i loko o nā palena o ka ʻāina anatomical, ke hoʻololi nei i ka wahi paʻa. Pono kēia e hōʻemi i ka hopena o ka lipodystrophy. Ke hoʻolilo nei ʻo Intramuscular a me ka ʻōlelo ʻana i loko o kahi vein e nā lāʻau lapaʻau wale nō. Hoʻohui pū ʻia ka insulin hana pōkole me kahi ʻano o ka insulin i kahi hopena therapeutic lōʻihi.

Me ka monotherapy me Biosulin, mālama ʻia kahi lawelawe hypoglycemic 3 mau lā i ka lā.

Hoʻolaha ka waipuna

Hoʻopilikia maikaʻi ka Ethyl alkohol i ka ʻōnaehana kaila a me ka hana o nā hana āpau a me nā pūpū. A hopena, hoʻohālikelike ka metabolism insulin, hiki ke alakaʻi i ka nalowale o ka mana o glycemic. Hoʻonui ka ulu ʻana i ka hypoglycemia. No laila, i ka wā o ka mālama ʻana me ka lāʻau lapaʻau, pāpā ʻia i nā mea inu wai inu.

Hiki ke hoʻololi ʻia ka lāʻau e nā ʻano o ka insulin wikiwiki.

• Insuman Rapid GT,
• Acfapid NM Penfill,
• Gensulin P,
• Humulin Pili.

Hōʻikeʻike e pili ana i Biosulin P

Ua hoʻokūʻē ka lāʻau iā ia iho i loko o ka mākeke lāʻau ma muli o nā manaʻo kūpono mai nā kauka a me nā mea maʻi.

Elena Kabluchkova, endocrinologist, Nizhny Novgorod

ʻO kahi papa hana e hoʻoneʻe ana i ka insulin e kōkua me ka emergency hyperglycemia i ka maʻi maʻi. He kūpono ka penikala syringe no nā mea maʻi me ka maʻalahi o ka manawa o ke ola a me ka hana. Hoʻokō kahi hana pōkole i ka wikiwiki me ka kō kiʻekiʻe. Mahalo i ka wikiwiki wikiwiki o ka hopena therapeutic, hiki iā ʻoe ke hoʻohana i ka pahu ma mua o ka ʻai ʻana. Ua ʻae ʻia ʻo Biosulin e hoʻohana ʻia me nā lāʻau ʻē aʻe e pili ana i ka insulin lōʻihi. Hiki i nā mea maʻi ke loaʻa ka lāʻau lapaʻau ma ke kumukūʻai.

Olga Atamanchenko, ʻoihana endocrinologist, Yaroslavl

Ma ka hana pilikino, ua kuhikuhi mua wau i ka lāʻau lapaʻau mai Malaki 2015. Me ka hiki ʻana o kēia ʻano o ka insulin i ka maʻi maʻi maʻi, e hoʻomaikaʻi ka maikaʻi o ke ola, ka hoʻohaʻahaʻa i ka hyperglycemia a me ka hypoglycemia. Hāʻawi ia no ka hoʻohana ʻana i nā keiki a me nā wahine hāpai. Mahalo i nā hana hana pōkole hana pōkole, hiki i ka mea maʻi ke alakaʻi i ka lāʻau lapaʻau i nā kūlana kūwaho (me ke kiʻekiʻe o ke kō. Manaʻo wau iā Biosulin he mea wikiwiki wikiwiki.

ʻO Stanislav Kornilov, 53 makahiki, Lipetsk

ʻO ka hoʻomaʻamaʻa wikiō hana maikaʻi. Ua hoʻohana wau iā Gensulin a me Farmasulin, akā hiki iaʻu ke hoʻokō i kahi hoʻohaʻahaʻa maikaʻi i ka hoʻokaʻawale ʻana o nā glucose i ka mahalo me Biosulin. Ua hoʻāʻo ʻo ka lāʻau lapaʻau iā ia iho me ka hui pū me Insuman Bazal - lōʻihi ka hana o ka insulin. Mahalo i ka hopena wikiwiki, hiki iā ia ke hoʻonui i ka ʻai o nā hua. ʻIke wau i nā lāʻau lapaʻau ma mua e hōʻeha pinepine koʻu poʻo, akā ʻaʻole ʻike ʻia kēia hopena. Ua hauʻoli wau i ka hopena, akā ʻo ka mea nui ka hahai i nā ʻōkuhi no ka hoʻohana a me ka meaʻai i kuhikuhi ʻia.

Oksana Rozhkova, 37 makahiki, Vladivostok

5 mau makahiki i hala, ua mālama ʻo ia i ka mālama pili i ka maʻi o ka maʻi mellitus o ka maʻi maʻi, ʻaʻole i ʻike ʻia e ia. I ka hōʻea ʻana i ka mana glycemic, ua kamaʻilio ke kauka e pili ana i ka maʻi maʻi a kuhikuhi i ka Biosulin ma kahi maʻamau. Ua ʻōlelo ʻo ia he ʻoi aku ka maʻalahi o ka hoʻohana ʻana i kahi peni ʻoisy. ʻOiai ua paʻi ʻia ka lāʻau lapaʻau, e noho mau ana ka nui o ke kō i loko o nā palena maʻamau. Akā ʻo kēia ʻano o ka insulin e hana pōkole ana, a pono e koho i kekahi ʻano ʻē aʻe me kahi hopena lōʻihi. Ua hopohopo wau ʻaʻole kūpono nā lāʻau lapaʻau, akā ʻaʻole i hoʻopaʻa ʻia nā kānalua. He mea maikaʻi no ka hoʻohui pū ʻana me kekahi ʻano like ʻole o ka insulin.