Ka maʻi pancreatitis me ka lawaʻole excretory: he aha ia?

Hoʻoulu ka pancreatitis maʻi me ka lawaʻole o ka exocrine me kahi kaʻina hana lōʻihi i ka pancreas (ma mua o 10 mau makahiki). Ma muli o ka hoʻololi o ka parenchyma me ka hoʻopili pili, hoʻoneʻe a ka hanu i ka hiki ke hoʻokō i ka hoʻoulu a me ka hana exocrine.

He maʻi koʻikoʻi ka maʻi no ka mea e alakaʻi ana i kahi mahele ʻāpana a hoʻopau paha i ka pancreas.

ʻO nā mea nui o ka pathology nā maʻi dyspeptic, ʻeha o ka ʻōpū, ke kuʻina, ka pallor o ka ʻili, tachycardia, ka pōkole o ka hanu, hoʻemi ʻia ka hiki ke hana a me ka mau ʻana o ka luhi.

ʻO ka hōʻailona nui o ka mumū pancreatic a me ka hana kīnā ʻole, ʻo ia ka hele ʻana i loko o ka kahi o ka paleka o nā meaʻai a undigested a me ka hoʻohui ʻana o ka momona. ʻO ke kumu kumu o ka maʻi maʻi o ka hoʻopaʻa ʻana o nā feces. ʻO nā mea kūpono o ka lāʻau kūpono, nā meaʻai kūikawā, ke kō ʻana o nā mea hoʻohui a me nā blockers pump proton.

Hōʻikeʻike o nā maʻi pancreatitis Chronic

I nā 30 mau makahiki i hala iho nei, ʻo ka nui o nā maʻi e loaʻa ana i ka pancreatitis heʻoi aku i ka pālua. Ua wehewehe ʻia kēia ʻano ma ka hōʻemi ʻana i ka waiʻona, ka maʻi gallstone, ka hana kino ʻole, a me ka ʻai o ka momona a me nā meaʻai ʻai. Ua ʻōlelo ʻo nā kauka, ʻo ka pancreatitis he "ʻōpio": ke nānā ʻia nei ka pathology ma ka awelika ma ka 39 makahiki, ma mua o ka makahiki he 50 mau makahiki.

ʻO ka papa pancreas he mea hoʻonaninani a me nā mea kuʻi intrasecretory. ʻO ka neʻe ʻana o waho ka hana o ka wai o pancreatic, a ʻo ka neʻe i loko o ka hana ʻana i ka hormone.

Hoʻopuka ʻia ka pancreatitis me ka hoʻōla ʻana o nā huina o ka digestive ma loko o ka huʻu ponoʻī iho. ʻO ka hopena, hoʻomaka ke kino i ka "hoʻoliu ʻana iā ia iho." ʻO ka maʻi pancreatitis (CP) kahi ʻano maʻi i hōʻike ʻia e nā loli degenerative i loko o ka pancreas. Me ka hoʻomau mau o ka pathology, fibrosis, nalowale a ʻaluhi paha o nā acini (nā kumumua hana o ka pancreas), nā hoʻololi i ke ʻano o nā auwē, a me ke ʻano o ka calculi i ka parenchyma i nānā ʻia.

E like me ka ICD-10, hoʻokaʻawale ka ʻoli ʻana i ka wai maʻamau a me nā mea ʻē aʻe. Wahi a nā ʻano puʻuwai ʻē aʻe, aia ka biliary-depend, parenchymal-fibrous a obstructive CP.

ʻAʻole i like ke ʻano o ke ʻano o ka maʻi, ke ʻano maʻi like ʻole o ka maʻi a i ʻole me nā maʻi concomitant, no ka laʻana, nā ʻōpū o ka ʻōpū a me nā ʻōpio duodenal, cholecystitis maʻi, biliary dyskinesia, etc.

E pili ana nā hoʻopiʻi maʻi o ka mea maʻi e loaʻa ʻana i ka maʻi pancreatitis me ka:

ʻeha nā hōʻeha ma ka ʻokoʻa hypochondrium,
ua ulu
hōʻā ʻia i ka paila a me ke ʻano o kahi ʻawaʻawa
ʻeha ka maʻi dyspeptic.

Hoʻomaʻama pinepine, ma muli o ka mau hewa o nā lula o ka mālamaʻai ʻana o ka meaʻai i ke kūpaʻa o ka papa o ka pancreatitis kūlohelohe, ʻike ʻia ka maʻi, i mea e hōʻike ʻia ai ka pau ʻole o ka meaʻai. ʻAʻole hiki ke maʻi ʻia kēia maʻi, no laila e koi ʻia ka hoʻomau ʻana a me ka lawe ʻana i nā lāʻau lapaʻau.

Ka hapanui o nā mea loea e hōʻike i ʻelua mau papa o ka papa o ka maʻi pancreatitis /

ʻO ke kahua I (mau makahiki 10 mua) - ka hoʻohalike ʻana o nā exacerbations a me ke kala ʻana, ʻaʻole i hōʻike ʻia nā maʻi dyspeptic, aia kekahi mau ʻeha ma nā wahi epigastric /

Stage II (ʻoi aku ma mua o 10 mau makahiki) - ka kōkua o ke kaumaha, hoʻonui ʻia ka maʻi dyspeptic.

Aia ia ma ka lua o ka papa ka ulu ʻana o ka pancreatitis maʻi me ka insufficiency excretory, kahi i hōʻike ʻia e kahi palupalu nui o ka pancreas.

ʻO nā kumu o ka hemahema exocrine

ʻO ke kaʻina o ka "hōʻiliʻili ponoʻī" alakaʻi i nā loli dystrophic i ka parenchyma a me ka hoʻopiʻi ʻana o ka wai pancreatic. E kū'ē i ke kua o kēia mau kaʻina hana, ka mea i hoʻopaʻa ʻia, a i ʻole glandular, pancreatic tissue i hoʻololi ʻia e ka ʻōpala kiko. I ka hopena, ʻaʻole hiki i kēia mau ʻāpana o ke kiko ke hana i ka hana exocrine.

ʻAʻole ia he kumu ʻo ka maʻi pancreatitis ʻaʻole wale ke kumu no ka hoʻomohala ʻana o ka exocrine insufficiency. ʻO kekahi kumu nui o kēia ʻano ka hiki i ka fibrosis cystic - kahi maʻi autoimmune e hoʻopā ana i nā kino e hana i ka wai kūlohelohe. Hoʻopili kēia i ka digestive tract, respiratory tract, pancreas, genitals, sweat glands, oral and hidal cavities.

ʻO ka pancreatitis kapa a me ka fibrosis cystic nā hana mua i loaʻa i ka hemahema o ka exocrine. ʻO nā hana o ka lua i loko o kona hoʻomohala ʻana e loaʻa i ke kaʻina pili pathological i ka hoʻopili ʻana o ka huina o ka huina o ka huina i loko o ka duodenum 12, ʻaʻole e hoʻomaikaʻi i ke kaʻina hana o ka ʻai.

ʻO kēia ma muli o kā lākou hoʻōla ikaika, ka hana ʻole a me ka hōʻino ʻana o ka hoʻokaʻawale ʻana. ʻO ka pancreatitis me ka lawa o exocrine, kahi mea i kūpono no ke kekona, he mau hiʻohiʻona. Aia, ke ʻano o ke ʻano o kēia maʻi e like me ke ʻano o ka "scenario" nei.

Hoʻokomo ʻia ka membrane o ka ʻāpana liʻiliʻi i nā mea maikaʻi ʻole. A ke hopena, ua hōʻemi ʻia ka hana ʻana o ka cholecystokinin a me nā mea huna.
Hoʻokumu kēia kaʻina hana i kahi hāʻule o ka pH intraduodenal ma lalo o 5.5. ʻO kēia ke kumu e hoʻohana ʻole ʻia ka enzyme pancreatic.
Aia he hōʻino i ka neʻe o ka meaʻai ma loko o ka pānaʻi liʻiliʻi. Hoʻomaka ka hana ʻole i nā enzyme digestive e hoʻohui me nā paleke o ka meaʻai e komo ai.
A ʻo kahi hopena, e hoʻomohala ke kaʻina o ke pala - kahi kūlana maikaʻi loa no nā huakaʻi pathogen. ʻO nā maʻi ʻē aʻe e hui pū me ka hoʻopiʻi o nā microflora kino. Ke hoʻonui nui ʻia o ka helu o nā huakini e alakaʻi i ka luku ʻia o nā enzyme digestive.
Hoʻomoe ka wai ʻai pancreatic, i hui pū ʻia me ka nele o ka hua bile a me ka enterokinase.

ʻO ke kānāwai, me ka wehe nui ʻana o ka pancreas (gastrectomy), ua pili nā mea ʻelua a me ka lua.

Ka helu ʻana a me nā hōʻailona o nā palola

Pono e helu ʻia nā mea huna pilikino e like me kekahi mau kumumanaʻo - ke kumu o nā pathology a me nā maʻi concomitant.

ʻO ke ʻano hiʻohiʻona

ʻO nā ʻano o ke ʻano

Nā kumu kumu o ka maʻi

Congenital - i ke ʻano o ka hopena genetic.

Loaʻa - e kū i ke kua o ka pancreatitis kūloko, etc.

Nā ʻōnaehana pili

ʻO ka pae mua - hiki i kahi kuʻikahi ke huna ʻia ma muli o nā loli pathological i ka parenchyma.

Ka lua - i ka wā o ka hana maʻamau o nā enzyme, ʻaʻole e ulu ʻia kā lākou hoʻoikaika ʻana i ka duodenum.

ʻO nā hōʻike nui o ka lawa ʻole o ka ʻike huna ʻē aʻe:

Ke hoʻomanawanui nei i nā momona, nā iʻa a me nā mea i inu ʻia. Inā ʻai ka mea maʻi i kēlā meaʻai, ma hope o kekahi manawa e loaʻa iā ia ka kaumaha i loko o kāna ʻōpū. A laila hoʻohui ʻia nā kaumaha colic. Ma hope o ke kau ʻana i ka ʻōpū, ua nānā ʻia kahi papa mushy - ka hōʻailona maʻamau o ka pancreatitis. Ma loko ʻike ʻoe e ʻike ai i nā haumia o ka moʻoʻala (momona) a me nā ʻikepili o ka meaʻai undigested. ʻO ka alapine maʻamau o ka hele ʻana i ka pahu he 3-6 mau lā i ka lā. Maʻalahi loa ka ʻike momona momona e ʻike ai: nā kīʻaha o nā feces e waiho pinepine i nā hōʻailona ma ka lua o ke kaena, ʻoiai ua paʻakikī lākou e holoi ka wai.
ʻO nā hōʻailona o ka nele o nā momona-soluble huaora. Ma muli o ko lākou nāwaliwali, ʻike ʻia ka ʻeha o ka iwi i ka ʻili. ʻO ka vitamin D hypovitaminosis e alakaʻi i ka pōpilikia, ka huaʻī K e alakaʻi i ka maʻi maʻi o ke koko, ka vitamin A i hōʻeha i ka "makapō pō" a me ka ʻili maloʻo, nā huaʻala o E e hoʻohaʻahaʻa i ka libido, a me nā maʻi maʻi pāpaʻi.
Nā hōʻailona ʻola e pili ana me ka nele o nā protere pancreatic.Hoʻopuka kēia mau enzymes i nā protein. ʻO ko lākou hemahema e alakaʻi ai i ka anemia B12-deficiency, ka mea i hōʻike ʻia e ke emi ʻana i ka hana hana, pōkole o ka hanu, ka pachor o ka ʻili, tachycardia a me ka wikiwiki wikiwiki. Ma muli o ka lawa ʻole o nā pono o ke kō, ua ʻike ʻia kahi emi wikiwiki i ke kaumaha o ke kino.

ʻO kēia mau kaʻina pili i pili i ka pākeke. I kona wā kamaliʻi, ʻo ka pancreatitis me ka hoʻokūkū o ka hana exocrine i ulu nui ʻole. Hoʻomaka ka huhū o nā mea maʻi no nā kumu ʻē aʻe - nā maʻi o ka ʻōpū liʻiliʻi, ka maʻi gallstone, nā hōʻeha ʻana o nā ʻōpū o ka ʻōpū, ka puʻuwai duodenal, ka hoʻopōmaikaʻi ʻana o nā pancreas a me nā kumuʻi pancreatic.

Nā hana Diagnostic a me ka maʻi maʻi

Ke ʻike nei i nā hōʻailona o ka palapeka pancreatic exocrine, pono ke kanaka e ʻimi i ke kōkua olakino.

ʻO ka nalowale o ka manawa kūpono hiki ke alakaʻi i ka hōʻino piha ʻana i ka pancreas a me kona lawe.

ʻO ke ala e ʻoi aku ka hopena ʻoi loa no ka maʻi maʻi. Kōkua ia i ka hoʻoholo i ke kiʻekiʻe o ka pancreatic elastase-1.

Hiki paha nā hopena o ke aʻo ʻana:

200-500 μg / g - hana lawelawe exocrine maʻamau.
100-200 mcg / g - ka maʻi maʻalahi a me ka maʻalahi o ka exocrine insufficiency,
ʻOi aku ma mua o 100 mcg / g - maʻi kaleha nui.

ʻO kahi hana nui i ka mālama ʻana i nā maʻi he meaʻai. I waena o nā lula kumu o ka meaʻai kūikawā no ka phocrine insufficiency, pono pono e hoʻolauna:

ʻAʻole eʻoi aku ma mua o 4 mau hola.
Pono ʻoe eʻai i nā ʻāpana liʻiliʻi nā manawa 5-6 i ka lā.
Hōʻalo i ka ʻai nui ʻana i ka meaʻai i ke ahiahi a me ka pō.
E haʻalele i ka meaʻaiʻai, nā momona a me nā mea uahi mai ka meaʻai.
E hāʻawi i ka makemake i ka meaʻai o ka mea kanu.
ʻAno kūʻokoʻa i ka inu ʻawa.

ʻO ke kumu o ka meaʻai, ʻo ia ka ʻai i ka ʻai paʻakai - nā lau ʻai, nā hua ʻai, nā cereals. He mau kumu ia no nā kaʻai ai i nā meaʻai, nā huaora, a me nā mea ʻelele a me nā elele macro. ʻAʻole ia e kuhikuhi i ʻai i nā meaʻai e like me ka legumes, kāpeti, ʻōpala, nā hua palaoa, no ka mea e hoʻonui lākou i ka pae kino i loko o ka ʻōpū.

Hoʻopili i nā lāʻau papaʻai, pono nā maʻi e lawe i nā lāʻau lapaʻau. ʻO ke kumu o ke ʻano o nā lāʻau lapaʻau:

ʻO nā enzymes Digestive e hoʻomaikaʻi i ke kaʻina o ka assimilation o ka meaʻai (Mezim, Pancreatinum 8000, Creon, Panzinorm). Lawe ʻia lākou i ka wā o ka pāʻina, ke hilinaʻi ʻia ka nui maʻa i ka nui o ka meaʻai e ʻai ai a me kona ʻano.
Nā mākena palaka proton e kōkua i ka hoʻokaʻawale ʻana i nā meaʻai (lanzoprazolol, esomeprazole, omeprazole). Hāpau ka hana o nā lāʻau lapaʻau e hana ana i ka hoʻokumu ʻana i ka hopena alkaline ma ka gastrointestinal tract kiʻekiʻe.

I kēia hihia, ʻaʻole pono nā lāʻau lapaʻau pilikino. Ma hope o nā kauoha a ke kauka, hiki ke loaʻa kahi hopena therapeutic maikaʻi. A me kahi hopena, e hala aʻe nā eha o ka palaki a me nā maʻi palaka, a ʻaʻohe ʻai e loaʻa ana i nā momona a me nā mea ʻaihue ʻole e kāhea ʻia i loko o ka papa. Mai ka manawa o ka manawa, ua hoʻomanawanui ka mea maʻi. Hōʻike ʻia ka normalization o ke kaʻina hana a kahi e hoʻemi ana i ka momona o ka momona ma nā feces a hiki i ka 7 g.

E kamaʻilio nā poʻe loea e pili ana i ka pancreatitis maʻi i ka wikiō ma kēia atikala.

ʻO ka ʻano o ka pilikia

Hana ka pancreas i 2 mau hana nui:

ʻO ka mea mua ʻo ka hana ʻana e ka hao hao o nā mea pili i ke kahe ʻana o ka meaʻai (wai pancreatic a ʻoi aku ka ʻoi o 20 mau ʻano o nā enzyme). ʻO kēia ʻāpana o ka pancreas he acini (nā lau gland cells) e synthesize i nā enzyme (trypsin, lipase, chymotrypsin, amylase, etc.), e wāwahi i nā protein, nā ʻaluna a me nā mea kākoi i komo i ke kino me ka ʻai i ka duodenum.

Hāʻawi ʻo Lipase i ka haki ʻana o nā hana i loko o nā momona momona i loko o ke kailei o ka pākia.

ʻO ka hapa endocrine o nā kipi ka mea mokupuni o Langerhans, aia ma waena o ka acini a me nā hui o ka insulinocytes e hana ana i ka insulin, glucagon, somostatin a me nā ʻano polypeptides i hoʻopili ʻia i ka hoʻololi o ka glucose a e hoʻoponopono i nā pae gula koko. Aia nā mokupuni i nā pū he A, B, a me D. Hoʻāla ʻia ʻo Glucagon i nā ʻōhua A (25% o nā mea āpau), nā B-cells (60% o nā mea āpau) pili i ka hana o ka insulin, a me nā pūpū o nā ʻano D (15%) e hoʻokaʻawale i nā polypeptides ʻē aʻe.

ʻO ka piha ʻana o pancreatic ma muli o ka luku ʻana o nā ʻili pono a me nā pūlepa i loko o ke kumulana a me kā lākou hoʻololi hou ʻana i nā ʻatikala hoʻohui (fibrosis), a laila e alakaʻi iā ia iho i ka hōʻemi o ka hana hana o ka lula i ka hana ʻana i nā enzyme pono a me nā hormones. No laila, hiki i ka pathology ke alakaʻi i ka hana hewa o nā ʻōnaehana o ke kino.

Nā ʻano o ka pancreatic insufficiency a me kā lākou mau hōʻailona

Hoʻololi ʻia nā maʻi maʻi pancreatic i 4 mau ʻano nui:

Ka hana o ka pancreatic Exocrine ma muli o ka emi ʻana o ka hana o nā mea i ʻike ʻia e hoʻoneʻe i ka meaʻai i loko o nā mea i hoʻoulu ʻia e ke kino, a i ʻole hōʻino ʻana i ka huna o ka mea huna i nā wai pancreatic i loko o ka ʻōpū ma muli o ka hoʻopulapula o nā kumu ma muli o ke kīpī a fibrosis. I ka hihia o ka hana pale ʻana i ka hana o ka enzyme, lilo ka mea huna i ka nui a nānā ʻole a hoʻokaʻawale i ka meaʻai. Ke hoʻopili nei i nā kahe kahe, ʻaʻole lawa o nā mea fermenting i loko o ka ʻōpū, ʻaʻole i hoʻopau me kā lākou hana. ʻO kāna mau kumu nui: ka hoʻomalokaʻana i nā meaʻai momona a me nā momona, nā kaumaha i loko o ka ʻōpū, ka ʻōpū, ka puhaka ʻAʻole hoʻonaninani ʻia nā ʻōpala i loko o nā pūniu a hoʻoulu ʻia i ka puka undissolved me nā feces (pancreatic steatorrhea). ʻO ka nele o nā momona momona e alakaʻi ai i nā iwi palupalu, kahi hōʻemi i ke koikoi koko, nā kīʻaha, nā pōkuhi o ka pō, ka impotence. ʻO ka emi ʻana o ka protein fermentation e hoʻolohi i ka pōkole o ka hanu, tachycardia, anemia, nāwaliwali maʻamau, a me nā luhi.
ʻO ka halaʻana o ka pancreatic excrine ka hopena o ka hōʻemi i ka hana o ka wai pancreatic (pancreatic) wai, nona ke kuleana maʻamau i ka hana gastrointestinal tract. Hōʻike ʻia e indigestion, puʻuwā a me ka kaumaha i loko o ka ʻōpū, ka nui o ke kinoea i loko o ka ʻalike a me ke kipi ʻana o kāna hana, ʻo ia ke kumu o ka hoʻomohala ʻana o ka maʻi mellitus. Hiki i ka pumehana Exocrine pancreatic kahi pilina a kūlike. A hoʻohuli ka mea mua, ʻoiai ka kūlohelohe o ka huelo i kēia hihia, ʻaʻole i uhai, ka maʻi kino e hoʻopiʻi ʻia e ka ʻōpū o ka pancreas a i ʻole ʻo ka mea huna kīnā ʻole, keu i nā keiki. Hoʻopiliʻia ka hemahema piha me ka atrophy o ka acini a me nā fibrosis o ke akeʻa pancreatic, kahi hōʻemi i ka hana o nā enzyme. He hopena ia o nā maʻi e like me ka maʻi a ma ke ʻano maʻamau o ka pancreatitis, cystic fibrosis, Schwachmann-Diamond syndrome.
ʻO ka hapa ʻole o nā enzyme i ka wai pākuhi i pili i ke kaʻina hana ʻana ka maʻi enzymeatic pancreatic. ʻO nā ʻōmohu e hōʻike ana i ka hemahema o nā huina no ka hoʻokaʻawale ʻana i ka meaʻai: flatulence, nausea a me ka luaʻi, ka pāʻana o ka fetid, dehydration, nāwaliwali nui, a me nā mea nui a me ka ʻano nui o ka hiki ʻana o ka enzyme he loli i loko o ka keʻena: he hoʻonui i ka nui o nā neʻe o ka ʻōpū, ka kīwī me nā momona nui, he hewa flobed i ka lua, huli i ka hina hina a make i ka stench stench.
Me ka nele o ka endocrine pancreatic, ka hoʻohaʻahaʻa o ka hormone insulin, glucagon, a me nā lipocaine i pau. Pilikia kēia ʻano o ka paʻa ʻole no ka mea e kumu ai kahi kuhi ʻole i ka hana o nā mea kino āpau a loaʻa nā hopena hiki ʻole. ʻO nā hōʻailona like like me ka mea me ka nele o nā enzyme pancreatic. Aia ka Insulin no ka hāʻawi ʻana o ka glucose i ke koko a i loko o nā puna o ke kino a hoʻohaʻahaʻa i nā ʻike o ke kō, e hoʻonui ana i ka glucoseagon. ʻO ke kumu o ka glucose i loko o ke koko he 3.5-5.5 mmol / l. ʻO nā hoʻololi i loko o ke kapu e alakaʻi i ka hoʻomohala ʻana i nā maʻi - hyperglycemia (hoʻonui i ka glucose) a me ka hypoglycemia (e like me ka hoʻohaʻahaʻa ʻana). ʻO ka hanaʻino o ka hana o ka insulin e alakaʻi ai i ka nui o ke kiko o ka glucose i ke koko a me ka hoʻomohala ʻana o kahi maʻi e like me ka maʻi diabetes.ʻO nā hōʻailona nui e hōʻike ana i ka hemahema o nā hormones insulin: hoʻonui i ke kō o ke koko ma hope o ka ʻai, ka make wai, ka urination pinepine, i loko o nā wahine - nā hōʻeha i ka ʻōpū. Me ka hoʻohaʻahaʻa ʻana i ka hana hana glucogan, ʻo kēia ʻano hōʻailona e hōʻike nei: ʻo ka nāwaliwali, nā helehelena, ka hoʻowalewale o nā alapine, hoʻololi i ka psyche (hopohopo, hōʻeha a me ke kaumaha, hopohopo e pili ana i ka hopohopo), ka hoʻopiʻi ʻana, nalowale o ka ʻike. Inā hoʻonoho kekahi endocrinologist i ka mālama ʻana i ka pilikia o ka insulin, a laila pono kekahi psychotherapist i ke kōkua me ka pohō o ka glucoseogan.

Nā kumu kumu o ka palaka ʻana o ka pancreatic

ʻO nā mea e hoʻopiʻi ana i nā malfunctions i ka pancreas hiki ke like me kēia:

nā loli degenerative i loko o ka wahī,
Ka nele o ka huaora (ka nele o nā huaora B, C, E, PP, hoʻonaninani nicotinic), e hoʻonāukiuki i ka maʻi o ka ate a me ka hoʻomohala ʻana i ka maʻi gallstone,
hōʻemi i ka protein a me ka anemia,
ka nāwaliwali i ka meaʻai - he nui nā momona, ka mea līʻai i ka meaʻai, inu ka waiʻona,
maʻi hopohopo o ka ʻōpū, pancreas, duodenum 12,
ka hana o ka pancreitis a me ka pancreitis kūlohelohe - nā mānoanoa o ka pancreas,
kekahaleona,
hoʻohana lōʻihi o nā lāʻau lapaʻau
ke ola kino
maʻi hōʻiliʻili maʻi
nā hana hōʻeha o ka ʻōpū liʻiliʻi a me ka duodenum, nā loli hoʻololi i ka microflora pono o ka ʻōpū,
malenations malenations o ka pancreas.

I ka manawa like, ua make ka pancreatic tissue a ua hoʻololi a hoʻoulu ʻia cicatricial a, ma muli o kēia, nalowale kā lākou hana hana.

ʻO ka maʻi ʻaia o nā loli pathological i ka pancreas

ʻO ka mea mua, ke hoʻokō nei ke kauka komo i ka hoʻokolokolo ʻana o ka mea maʻi, ʻike i nā hōʻailona e hoʻokaʻawale i ka maʻi pancreatic enzyme. E hōʻike i ka maʻi, hoʻomaʻamaʻa ʻia nā hoʻokahe koko laboratory (no ka ʻike o nā hemoglobin a me nā mea biochemical, no ka nui o ke kō), nā haʻawina o ke ʻano o nā enzymes i ka urine, ka nānā ʻana o nā feces a me kahi coprogram no nā kiko o nā momona (ma mua aʻe o ka 7%), elastase-1 a me ke ʻano o ka assimilation a e kaohi ʻana i ka meaʻai ma ke kino.

No ka hoʻomaopopo ʻana i nā loli degenerative i loko o nā kino, ua hoʻonā ʻia ka ultrasound o ka ʻōpū o ka ʻōpū, CT a me MRI. ʻO kahi ala nui e pili ana i ka diagnostic ʻo ka endoscopic retrograde pancreatocholangiography (ka nānā ʻana i nā kumu no ka pancreatic a me nā kumu pīpī no ko lākou kuʻi a me ka loaʻa ʻana o nā keloid formations). I mea e wehewehe ai i ka maʻi maʻi, hoʻohana ʻia kahi ʻano e aʻo pololei i ka mea huna i loaʻa mai ka pancreas ma ka makemake ʻana i ka pancreas, kahi e hiki ai ke hoʻoholo i nā ʻike a me ka nui o ka wai pancreatic.

Hoʻowalewale ʻia ka huakaʻi Endocrine e ka hoʻāʻo ʻana i ka hoʻokaʻawale glucose. E hōʻiliʻili ke koko ma kahi ʻōpū ʻole a me ke koko i hōʻiliʻili ʻia me 2 mau hola ma hope o kahi pāʻina a 75 g o ka glucose. Hōʻike kēia hōʻike i ke hiki i ke kino e hana i ka insulin a me ka hoʻoili glucose.

Hōʻike ka hōʻike ʻana i kēia mau hōʻailona i ka hoʻololiʻana i ka glucose metabolism: kahi pae glucose koko ma kahi o 6.7 mmol / L, 2 mau hola ma hope o ka laweʻana he 75 g o glucose - 7.8-11.1 mmol / L. ʻO ka maʻamau, ʻaʻole pono nā glucose koko i ka 6.4 mmol / L. Inā ʻike ka nui o ka glucose i ke koko i lawe ʻia ma kahi ʻōpū ʻole i ka hapalua o ka 7.8 mmol / l a i ʻole ma mua o kēia waiwai, aia ka maʻi maʻi.

Ke hoʻomaikaʻi nei i nā maʻi pancreatic

No ka hoʻoponopono ʻana i ka hana a hoʻopau i nā maʻi pancreatic, ua kuhikuhi ʻia ka mālama ʻana ma muli o ke ʻano o ka nele. Inā ʻike ʻia nā hōʻailona o ka maʻi e hōʻike ana i ka nele o ka enzyme, ua ʻōlelo ʻia nā lāʻau multienzyme e hoʻohuli i nā mea o ka huina o ka huina.

Ka hoʻōla ʻana o ka pancreatic Exocrine i kumu o ka nele o ka pancreatitis intrasecretory e mālama ʻia me nā lāʻau lapaʻau e loaʻa ana i nā enzymes (Mezim-forte, Pancreatin, Creon, Panzinorm-forte), ua hoʻolako ʻia e hoʻohana i nā mea paʻakikī o ka huaʻai i loaʻa ka momona-soluble mau huaʻala A, D, E, K.ʻO ka lāʻau kūpono loa ʻo ka Mezim-forte, nona ka protease, amylase a me ka lipase, hiki ke hoʻohana ʻia e nā maʻi maʻi o nā makahiki ʻōpio.

Hoʻomaʻaʻa i ka papa ʻai kekahi papa e kuhikuhi ana i ka kaohi ʻana i ke kōpaʻa koko a mālama i nā lāʻau lapaʻau i kuhikuhi ʻia no kēlā me kēia mea maʻi. Pono ka ʻōpū a me ka maʻamau (5-6 mau manawa i ka lā), pono e ʻai i nā mea ʻai a me nā mea ʻaiʻai i momona i ka ʻai (palaoa a me ka oat bran), a me nā meaʻai pūmua.

Me ka hoʻohaʻahaʻa ʻana i ka hana o ka enzyme, nā lāʻau lapaʻau e hoʻopaʻa ana i ka ʻāina alkaline i loko o ka digestive tract (Omeprazole, Pantoprazole, Lanzoprazole, etc.) i kuhikuhi ʻia e hoʻonui i ka hiki ke kūwali. Ke kuhikuhi nei i ka lāʻau mālama i ka mālama ʻana i nā kumu o nā maʻi: nā maʻi o ka ʻōpū, ka pancreas a me nā ʻōpio 12 duodenal.

ʻO ka hoʻomaʻamaʻaʻana o ka lawa o endocrine e hilinaʻi nei i ka maʻi i hopena mai ka hapa ʻole o kekahi a i ʻole kekahi ʻano ʻano o ka hormone. ʻO ka maʻi maʻamau i mea maʻamau ka mellitus o ka maʻi mellitus, hoʻomehana ʻia e ka lawa ʻole o ka hana o ka insulin, e alakaʻi ai i ka piʻi o ke kaila glucose. Hoʻokumu ʻia ka mālama ʻana i ka maʻi diabetes i nā kumumanaʻo 3: hoʻohui hou i ka insulin, hoʻihoʻi i ka metabolic a me nā maʻi hormonal, a me ke pale ʻana i nā hōʻeha hōʻeha.

ʻO ka mea nui ka meaʻai, ʻo ka hoʻonui ʻana i ka hana kino o ka mea maʻi, ka hoʻohana ʻana i nā lāʻau lapaʻau e hoʻohaʻahaʻa i nā kiʻekiʻe o ke kō, a me ka maʻi insulin (no nā maʻi maʻi insulin. Pono ka papa ʻai i ka 60% o nā hoʻohaʻahaʻa o ka hoʻohaʻahaʻa iki (brown brown, palaoa bran with pectin), 24% o nā māmā māmā a 16% o nā meaʻai o ka protein. Hāʻawi i ka papaʻai no ka hōʻaiho piha ʻana i nā huahana e loaʻa ana nā sucrose a me ka fructose, maʻalahi i ka hoʻokaʻawaʻu ʻawaʻawa (kaomi, ka palaoa a me nā huahana i hoʻoponopono ʻia, nā hua momona, nā mea momona carbonated), ke kaupalena ʻana o ka paʻakai a me nā mea lae, kekahi mau ʻano o ka loea.

Ma muli o ka nui o ka hana kino, hoʻopau ʻia ka glucose me ka ʻole o ke komo ʻana i ka insulin. No nā poʻeʻelemakule a me nā mea maʻi me nā maʻi ʻē aʻe, ʻo ka hele ʻana o kēlā me kēia lā no 1-2 mau hola a i ʻole ka wikiwiki wikiwiki o ka liʻiliʻi loa 40 mau minuke.

ʻO ka koho a me ka nui o nā lāʻau lapaʻau e hoʻemi ana i ke kiʻekiʻe o ke kōpaʻa koko, e hana ana e ka neʻe ʻana i ka endocrinologist e pili ana i ka loiloi. E like me ke kānāwai, ua hoʻohālikelike ʻia ʻo Glucophage, Siofor, Metamorphine, Glutazone, Actos, Pioglar, a pēlā aku.

Hoʻokomo ʻia nā ʻaina Insulin-substituting no ka holomua o ka maʻi diabetes, i ka wā e hoʻomaʻamaʻa ana ka pancreas e hana i ka insulin. Aia he 2 mau hiʻohiʻona derivative a me nā hoʻomākaukau insulin:

Nā waihona kālā mai nā ʻāpana o ka insulin o ke kanaka (ʻenehana recombinant DNA a i ʻole semi-synthetic).
Nā waihona kālā i lawe mai i nā māhele o ka insulin o ka hoʻomaka ʻana o nā holoholona (ʻo ka hapanui mai ka puaʻa).

ʻO ka ʻoi loa ka mākaukau me ka hoʻomākaukau ʻana i nā insulin a nā kānaka.

ʻO nā wānana no ka pihaʻana o ka pancreatic i waiho i kahi nui e makemake ʻia. Pili ia i ka pae o ka hōʻino i ka parenchyma. Kuhi i ka ulu ʻana o nā patology e pili ana i ka hope o ka make o kahi mahele nui o ke okana, pono ka lāʻau lapaʻau ma ʻokoʻa o ke koena o ke ola. Hiki ke pale i ka hoʻomohala ʻana o kēia ʻano ma ka manawa kūpono a me ka mālama ʻana i nā maʻi pancreatic, hōʻole i ka inu ʻawa, a me ka uahi.

Hoʻopilikia kekahi hana

E like me ka laha ʻana o ka pancreas a pālahalaha aʻe i ka pancreatitis ʻole, ke kihi glandular o ka ʻāpana i loko o nā kelepona e waiho ana a make a me nā ʻono a me nā ʻili palaki ma kona wahi. Ka mea, me kahi hoʻohaʻahaʻa i ka nui o nā cell acinar (secretory) o nā kohu, ke emi iho nei kāna hana, ʻo ia hoʻi, ʻo ka hana a me ke komo ʻana i ka ʻāpana o ka mea pono no ka hoʻoneʻe ʻana o nā enzyme.

ʻO nā hana nui o nā cell acinar o ka gland e pane i ka hāʻawi ʻana i ka meaʻai, ka hoʻomohala ʻana a me ka hāʻawi ʻana i ka wai pancreatic i hui ʻia me nā enzymes a me alkali i ka duodenum o ka duodenum 12. Ma kona kūlana maʻamau, loaʻa i ka hiʻona pancreas kahi pūpū holoʻokoʻa o nā enzyme e pono ai e hōʻemi pono i ka momona, nā protein a me nā ʻaluna.

No ka hana ʻana, he hāmeʻa e like me lipase e pono no ka hoʻokaʻawale ʻana i nā momona momona a ma kaʻili o nā momona. ʻAʻole hoʻokahi lālā o ka digestive tract e hoʻokaʻawale i kahi mea hiki i ka hapa ʻokoʻa ma ke kau ʻana i nā hana lipase. No laila, ma ka make o kahi ʻāpana o nā mea huna e pili ana i ka pancreatitis, ma ka mua, aia kahi kaʻi o ka hana ʻana i nā enzyme no ka hoʻōla ʻana i nā momona a me nā momona i hoʻoliʻiliʻi mau ʻia, e pili koke ana i ka hōʻeha ʻole i ka wā e ʻai ana me ka mea liʻiliʻi o nā mea momona. ʻO kaʻai ʻana o ia mau kānaka e maʻamau i ka papa ʻaina, kahi e hoʻopilikia kino i ka maʻi maʻamau.

Me ka holomua o ka maʻi pancreatitis a me ka nele o ka exocrine, a me ka loli o nā ʻāpana nui a ʻoi aku ka nui o nā kelepili hoʻohui glandular, ʻike ʻia nā hōʻailona o ka hopena endocrine, hoʻomohala i ka mea maʻi.

Nā kumu a me ka hoʻonohonoho ʻana o nā pathology

Ka helu ʻana i nā kakaho pancreatic exocrine e pili ana i nā kumu o ka haʻi ʻole ʻana o ka hana huna, nā maʻi concomitant a me ka nui o ka lesion. ʻĀina:

ʻO ka hikiʻole o Congenital ma muli o ke ʻano lahilahi e kāohi ana a pale ʻole paha i ka hana o nā enzymes.
Loaʻa, ulu i loko o ke ola holoʻokoʻa, nui loa ma ke kūkaʻi ʻana o ka maʻi pancreatitis.

ʻO ka hana ʻana o nā hana pancreatic exocrine, ʻoiai he maʻi kūʻokoʻa ʻole a i ʻole ka hopena o ka ʻoli ʻē aʻe, ua ʻae ʻia e kāua i ka maʻi i loko o:

ʻO ka mua, kahi i hele mai ai nā maʻi patological ma muli o ka maʻi ʻeha o ka pancreas pono a me ka pale ʻana o ka syntzim synthesis.
ʻO ka lua, kahi i piha ai ka hoʻoliʻiliʻi o nā huina, akā kā lākou hoʻōla i ka 12 duodenum a me ka'ōpala liʻiliʻi ʻaʻole i kū a ulu ʻole kā lākou hana.

ʻO nā kumu o ke ʻano nui o ka piha ʻana i ka pancreatic pancreatic o nā ʻano a me nā ʻano a me nā ʻano o ka pancreatitis kino, a penei hoʻi:

cystic fibrosis - kahi maʻi congenital o ka hana pilikino i hele pū ʻia me nā pilikia hana,
nā maʻi hōʻoki o ka pancreatic, ʻelua hōʻino a me nā maleign,
ka hoʻonāukiuki ʻana o nā maʻi pancreas me ka momona koʻikoʻi,
nā hopena o ke kaʻina
kaolea enzymatic deficiency,
ʻO ka maʻi a Schwahman
ʻO Johanson-Blizzard syndrome,
ʻOa hypoplasia pancreatic a i ʻole agenesis,

Hoʻohālikelike pinepine lākou i ka emi ʻana o ka hana exocrine, fibrosis a i ʻole atrophy, i ulu ʻia e kū kū'ē i kahi kumu o:

alakaola (pancreatitis alikaʻi, pancreatitis calculous)
kokohiwi,
ka hana mau ʻana i ka meaʻai, ʻole ka hahai ʻana i kekahi ʻano o nā meaʻai a me ke kaohi ʻana i nā mea momona a me nā momona.
hemosiderosis - dystrophy pigmentary me ka nui o ka hōʻiliʻili ʻana i nā kiko o ka hemosiderin - he kumu pālima hao.
maʻi ma muli o nā maʻi o ka maʻi pancreatitis,
ʻO ka maʻi pancreatic,
ʻO ka neʻe ʻana o ka pancreatic - ʻāpana hapa a piha paha i ka maʻi pancreatic,
ka hoʻokumu ʻana o nā pōhaku i nā kumu no ka pancreatic.

ʻO nā kumu o ka puka lua o ka piha ʻana o ka pancreatic exocrine he mau ala no ka ʻōpū liʻiliʻi, no ka laʻana:

gastrinoma - kahi ulu paʻa hana,
hana ʻino
ʻaʻole lawa o ka enterokinase enzyme,
nā maʻi pili ʻole o ka ʻōnaehana hepatobiliary,
ʻohi-kaohi ʻana i ka protein,
nā hopena o nā hana ma ka ʻōpū a me nā ʻōpū paha.

ʻO ka hemahema a me ka pili o ka enzymatic insufficiency o ka pancreas kahi i hoʻokaʻawale ʻia.

ʻO ka hemahema piha loa he nui, a ulu a kūʻē i ke ʻano o ka hoʻemi ʻana i ka nui o ka parenchyma, ma muli o ka nele o ka huna ʻana o nā enzyme a me nā bicarbonates. Ma ka hoʻomaʻamaʻa kulekele, ʻike pinepine ʻia kēia palapala.

ʻO ke kumu o ka piha exocrine insufficiency ka congenital a loaʻa nā pathologies. ʻO ka manawa pinepine, ʻo ka maʻi o ka maʻi pancreatic excrine pancreatic e nānā ʻia i loko o nā keiki me nā anomalies congenital e like me:

hypoplasia pancreatic,
ʻO ka pancreatitis o kāna ʻano hoʻoilina,
māhuahua o nā kumu o ka papa.

ʻOi iki ka liʻiliʻi, ua loaʻa mai kēia ʻano maʻi o ka maʻi no ka maʻi i loaʻa. ʻO ka pōʻino nui loa o lākou ʻo ka maʻi pancreatitis a ʻo ka pancreatitis aʻoki maoli e hōʻoluʻolu ʻia e nā lāʻau lapaʻau.

Hoʻoulu ka loulou o ka pilina maʻamau ma ke ʻano he ʻano lua o ka maʻi, a pili pū me ka paʻakikī paʻakikī o ka huna ʻana o ka pancreatic i loko o ka lumen o ka pahu liʻiliʻi a i ʻole ka wikiwiki o kāna hana. ʻO ka maʻamau, me kēia ʻano, hana nā kelepa pancreas i kahi ʻano maʻamau, akā ʻaʻole paha ka manawa i nā manawa e hoʻopau ai i kā lākou hana a ʻaʻole hiki ke hana i kēia ma muli o ka blockage a ʻāpana paha. ʻO nā mea nui i nā puʻupuʻu, nā tumors a i ʻole nā hana pōhaku nā mea e pani ai i ka wai pancreatic.

ʻO ka maʻa o ka hōʻino i ka hoʻopulapula pololei o exocrine o ka gland i ona mau hiʻohiʻona pono. ʻO ka maʻamau, ulu ka pathology e like me ke ʻano o ke ʻano he ʻano.

I ka nāhina o ka ʻāpana liʻiliʻi, nā mea i hoʻopau ʻia no nā kumu like ʻole, ua hoʻemi nui ʻia ka huna ʻana a me ka hana cholecystokinin.
Ma muli o ka emi ʻana o ka waiwai o ka pHdaduodadu pH ma lalo o 5.5, ka mea e pono ai no ka hoʻouluʻana i nā enzyme pancreatic. I ka hopena, ʻaʻole hiki ke hoʻāla ʻia nā huina mai nā pancreas.
Hoʻololi ka ka haki ʻana o nā meaʻai ma nā kaʻi liʻiliʻi liʻiliʻi, ka mea e alakaʻi ai i ka hoʻohui ʻana o nā enzyme unactivated me kahi ʻaka momona.
Hoʻokumu ka hoʻokuʻi i nā kūlana maikaʻi loa no ka ulu ʻana a me ka hana ʻana o ka microflora pathogenic, a me ka loaʻa ʻana o ka maʻi maʻi. Ke hoʻomake nei ka ulu ʻole ʻana o nā pūpū palupulu liʻiliʻi i nā enzyme i loaʻa.
Hoʻohālikelike ʻia ka pale ʻana i ka holomua o ka wai pancreatic ma ka loaʻa ʻole o ka hua bile a me ka enterokinase.

Eia kekahi, hiki i ka uluʻana o ka exocrine ke ulu ma muli o ka hoʻokē mau ʻana i ka ʻaina a i ʻole kahi meaʻai me kahi haʻahaʻa haʻahaʻa haʻahaʻa. Kēia hemahema o nā meaʻai o ka protein e hoʻonāukiuki i ka hana o ka enzymatic o ka pancreas, a me ke kumu o ka maʻi pancreatitis.

Nā hōʻailona a me nā hōʻike kino

ʻO ka hōʻailona mua a me ka mea nui o ka exocrine pancreatic insufficiency kahi maikaʻi maikaʻi o ke kino i nā mea momona, ʻoi aku ka wā e pīpī ai, me ka hoʻohui o kekahi mau mea ʻala wela.

ʻO ka mea hoʻomanawanui e hoʻopiʻi i kahi ʻeha o ke kaumaha, nausea, ka ʻawaʻawa, ke hoʻololi ʻana i ka ʻaʻa ma hope o ka ʻai ʻana i kahi pā momona. Aia kēia mau hōʻailona āpau o ka holomua o ka hōʻemi ʻana i ka hiki ke hoʻāʻo ʻana ma ka ʻāpana liʻiliʻi.

Me ka hoʻomohala ʻana i ka maldigestion, nā kaʻaʻai undigested e holo wikiwiki i loko o ka ʻōpū nui, kahi e hoʻonaninani ʻia ai ka ʻikepili kolokaluna. Ma muli o kēia, aia kahi hewaʻole o ka caloforming a me ka nui o ka neʻe ʻana i ka neʻe pana. Hoʻomaopopo nā hōʻailona o ka steatorrhea, nā luʻu o kahi pale hina hina me kahi mea hoihoi fetid, a me kahi pāla nani e hoʻonaninani ʻia, a i ʻole he statics statics. Hiki iā ʻoe ke nānā pū i kahi hoʻohui o nā ʻāpana like ʻole. Piʻi pinepine ʻia ka maʻamau o ka neʻe, hiki i ka nui o nā mīkini ke piʻi i 6 mau manawa i ka lā.

I ka hoʻomanawanui, ʻike ʻia nā hōʻailona e like me ke kuʻe ʻana a me ka hōʻeha ʻana ʻo colicky.Hōʻemi ka hana o ka hoʻemi ʻana i ka protein hoʻoneʻe i ka kaohi o ka nui o ka protein, i hōʻike ʻia ma ka hoʻomau ʻana o ka lawe ʻana i ke kau, a me ka anemia. ʻO ka hapa nui o ka hapa nui o nā huaora, nā macro a me nā trace, me ka dehydration he mea weliweli loa no nā keiki. Hiki i kēia kūlana ke hoʻoweliweli ola.

Hoʻopili i ka hoʻokaumaha ʻia o ka meaʻai paʻa loa, a me ka makaʻu hoʻi i ka meaʻai i hopohopo ʻia e ka makaʻu ʻole ʻana ma hope mai o ka ʻoluʻolu, e hāʻawi hou i ka lilo ʻana o ka mea kaumaha.

Ke hoʻonui nei ka hoʻonui ʻia ʻana o nā momona a me ka momona o ka momona - i hōʻike ʻia ma ke ʻano o ka hōʻeha ʻana i nā iwi a me nā hui, nā hōʻea nā wā, hoʻonui pinepine ʻia - ka hapa o ka vitamin "D".

ʻO ka nele o ka bitika K e hoʻoulu i ka huhū, a me ka huaora A hypovitaminosis e alakaʻi i ka hihiʻo o ka nui o ka ʻili maloʻo a me nā kui palu a me ka lauoho.

Loaʻa ka mea maʻi i ka hōʻailona e like me:

ʻālehu ʻāʻī o ka ʻili,
nā hōʻeha o ka pōkole o ka hanu a me ka tachycardia ma hope o ka hoʻoikaika kino kino kino,
luhi a me nā nāwaliwali mau.

ʻO kēia mau hōʻailona kēia ka hōʻailona o ka "B12" koʻikoʻi - hemahema anemia.

Nā hiʻohiʻona o ka hemahema exocrine i nā keiki

ʻO nā maʻi o ka pancreas i nā keiki he mea maʻamau ʻole, akā ʻo ka mea nui ka nui o nā ʻano genetic, ʻoiai ʻo nā hihia hou o ka pathologies i loaʻa he nui. Hoʻololi ʻia ka maʻi pancreatitis o nā keiki, ʻelua a me ke koʻikoʻi, i nā manawa ʻelua. Hōʻino ka poʻe hoʻonaʻauka i kēia nāwaliwali o ke ʻano o ke kaiapuni, ka hoʻohana ʻana o nā huahana ʻoihana i loko o ke kīpē o ka pēpē, wīwī mua, ka hoʻololi ʻana i ka waiū umauma me nā ʻano maikaʻi o ka maikaʻi, ka hoʻolauna mua ʻole ʻana o nā meaʻai piha, a me kahi kīnā kūpono ʻole nā makahiki.

Nā hōʻike lapaʻau a me nā hōʻailona o ka pancreatitis, ka hemahema o ka exocrine, e like me nā mea maʻi pancreatic ʻē aʻe i nā keiki, e like me ka pancreatitis koʻikoʻi, he mau ʻokoʻa a me nā hiʻohiʻona e like me ke ʻano o ka pathology.

He microsic fibrosis

ʻO nā pathologies genetic a me nā abnormalities hoʻomohala i nā keiki e hele mua i ka papa inoa o nā kumu o ka pancreatitis. ʻO Cystic fibrosis, kahi mau mālamuhō congenital i ka hana pilikino a me nā ʻino kino, ʻo ia ke kumu maʻamau o ka hoʻopiʻi ʻana o nā kelepa exocrine.

Hoʻokumu ka pathology ma muli o nā loli mutational o ka hua, i mea e hoʻoponopono ai i ka hui ʻana a me ka hana hana o ka protein. Aia kēia gen i loko o nā lau o ka bronchi, ka ʻili liʻiliʻi, nā māmā, nā mea ola o ka ʻōnaehana genitourinary, akā ʻo ka hapa nui o ia mea i nā cell epithelial o nā papa excretory o nā pancreas. Hoʻomaopopo mua ka maʻi maʻamau i ka ʻeha a me ka pancreas. Hoʻokumu ke keiki i ka pancreatitis maʻi a me ka lawaʻole o ka exocrine koʻikoʻi.

Hoʻomaʻamaʻa ʻia, hōʻike nei ka pathology e nā hōʻailona o ka steatorrhea. Pale pinepine kēlā mau keiki iā bronchitis a me nā maʻi pneumonia, a lohi loa ka hoʻolaʻa ʻana. Loaʻa iā lākou kahi moʻaukala o ka gophitis atrophic a me ka enterocolitis, a me ka maʻi pancreatitis.

ʻO ka hoʻomaʻamaʻaʻana o ka lawa o ka exocrine i kēlā mau keiki hoʻomaka mai ka manawa o ke ʻano maʻi a hoʻomau i ke ola ʻana. Hoʻokomo pū ʻia nā lāʻau lapaʻau i kahi mea ola holoʻokoʻa, ua kau inoa ʻia ka meaʻai e ka kauka e like me nā hopena o nā hoʻokolohua hou loa, nui o nā nui o nā hoʻomākaukau ʻana no ka pancreatic, nā ʻaihue a me nā huaora. ʻAʻole kūpono i ka prognosis, ʻoiai ua pili nā kino o nā ʻāpana āpau. ʻAʻole hoʻi e hoʻihoʻi ʻia nā cell o ka pancreas.

ʻO ka maʻi a Schwahman

ʻO ka maʻi congenital o kahi ʻano maʻamau, i kapa ʻia ʻo Schwahman's syndrome, i hōʻike ʻia i ka nele o kahi enzyme lipase e kuleana ai ka ʻāʻī, hoʻoneʻe a me ka hoʻokaʻawale i nā ʻeha momona. Hōʻike kēia ʻano o ka hana exocrine i nā keiki ma muli o kahi kolohe i loko o ka manawa o ka hoʻomohala ulu.I ka manawa i hoʻomohala ʻia o ka pancreas, loaʻa kekahi kuhi hewa, ka mea e alakaʻi ai i kona underdevelopment a i ʻole hypoplasia. Ma ka hōʻike koko, he keiki nā neuropenia, thrombocytopenia a me nā maʻi maʻi kuʻuna. Nui nā keiki i hope o ka ulu ʻana mai kā lākou mau hoa, ʻoi aku ka palaka o ke poʻo o ka iwi o ka ʻāʻī a i ʻole kuʻekuʻe wāwae paha, kahi ʻāʻī liʻiliʻi liʻiliʻi, ka hypoplasia o nā phalanges.

Aia ke kiʻi o ka lāʻau lapaʻau:

mākaʻi
nā hōʻailona o ka pancreatitis,
maʻi mellitus maʻiʻi
sinusitis
otitis media.

Hoʻopili ke keiki i nā maʻi ʻili, a hoʻomanawanui mau ʻia mai nā maʻi ʻeha. Pono kahi meaʻai paʻa.

E like me ka cystic fibrosis, ʻo ka mālama ʻana i ka hoʻōla ʻana me ka lāʻau lapaʻau pancreatic, i kekahi manawa me ka antibiotics. Hoʻopili pololei e like me ka pauna i ʻōlelo ʻia ai. Hoʻohana ʻia ka meaʻai i nā mea a pau a ua hoʻopaʻa ʻia hoʻokahi.

ʻO ka pancreatitis

ʻO ka pancreatitis Ac a hōʻoki ʻole paha kahi kūlana maʻamau i nā keiki. ʻO ka kumu, hoʻonāukiuki i ka pancreas ma kahi keiki e kū'ē i ka hope o nā ala āpau i loaʻa ka hopena maikaʻi i ka hana o ka lula.

No ka laʻana, ʻaʻole wale ka pancreatitis mau mea e hoʻonāukiuki a hōʻoki paha i ka hana huna, akā:

maʻi ʻeha maʻa liʻiliʻi
halihali
ZhKB - cholelithiasis. I nā makahiki i hala iho nei, ua hoʻonui nui ʻia ka nui o nā hihia o ka cholelithiasis i nā keiki ma lalo o 10 mau makahiki.
mea ʻeha i ka ʻōpū a me ka ʻōpū,
ka halaʻole o ka hoʻomohala ʻana o ka pancreas a me nā kumu moana.

Pono ke kīleʻa no ka lawa ʻole o ka hakahaka, e like me ka maʻi pancreatitis, pono ʻole ke hoʻopau ʻia. Hōʻalo ka meaʻai kiʻekiʻe i loko o nā mea momona maʻalahi a haʻahaʻa loa i ka momona a me nā momi. Pēlā nō hoʻi i ka papa ʻaina meaʻai nui ka nui o nā huaora e pono ai no ka hoʻoneʻe ʻana.

Eia kekahi, ʻo kahi kūlana koʻikoʻi o ka meaʻai he nui ka wai a me ka sodium chloride.

I ka hopena

Hāʻawi nā ʻano hana o kēia mau poʻe i ka poʻe e hōʻeha nei i ka manawa a exocrine i hiki ke alakaʻi i kahi ʻano hana. ʻO ka hoʻokō me ka haʻawina i kuhikuhi ʻia no ka pancreatitis maʻi he hopena kūpono ma ke kūlana. Hoʻoikaika mau ka hana pilikino.

ʻO ka hoʻokō ʻana i ka meaʻai, ka mālama paʻa ʻana i ka ʻai, a me nā lā lāʻau lapaʻau e uku ai i ka nele o ka pancreatin a me nā enzyme pancréipase, hōʻike i nā hopena maikaʻi loa.

ʻO ka pancreatitis hina, ʻo ia ka ʻenemi nui o ka pancreas, ʻoi aku ka maʻalahi o ka pale ʻana ma mua o ka mālama ʻana i kahi meaʻai no ke ola, me ka papa inoa o nā huahana.

ʻO ke komo ʻana o ka pancreas i loko o ka ʻike ʻana

Hōʻike ka Digestion i ka hoʻoili ʻana e nā enzymes o nā mea paʻakikī (nā palepale, nā momona, nā mea hōʻemi) i nā mea maʻalahi no ka hoʻopili ʻana ma hope.

ʻO ka nui o nā kaʻina hydrolytic nui e hana i loko o ka ʻōpū liʻiliʻi, kahi e wāwahi ʻia nā mea aʻai i nā monomers, hoʻopili, a komo i ke koko a me ka lymph. ʻO ke kaʻina hana e hoʻōla ai i nā huaʻai i loko o ka pahu ʻuʻuku e loaʻa i nā hanana kūmole i hui pū ʻia, hui ʻia e A. M. Ugolev (1967) ma ke ʻano o ka "digestive-transport conveyor": kūwili ana i ka lua, ʻāwī o ka membrane, hoʻopili.

ʻO ka papa mua o ka lawe ʻana i ka halihali halihali - ka hana ʻana o ka lua Hāʻawi kahi hana koʻikoʻi i ka hana kūwaho o ka lua i nā enzyme pancreatic.
ʻO nā enzyme pancreatic i hoʻopiʻi ʻia i nā mea momona e hoʻomau i ka hana o ke ana i ka hana e hiki mai ana, i ka pae parietal o nā mālamus. ʻO ka hana hope loa o nā mea kanu kūpono e kū ana ma nā membrane waho o nā enterocytes e hoʻohana ana i ka hydrolases intestinal - ʻo ia ka hana ʻana o ke membrane.
A laila hele mai i kahi hope hope loa - ka hoʻoili ʻana, i.e., ka hoʻololi i nā māhele hoʻokaʻawale o nā mea kanu mai ka lumen o ka ʻili i loko o ke ʻano o loko o ke kino.

Hoʻokumu ka pancreas i kahi mea huna e loaʻa ana i nā enzyme e hoʻonoho i nā ʻano momona āpau: nā protein, nā mea i kālai ʻia, nā momona. Kuhi ʻia ka papa inoa o nā kinohi pancreatic nui a me ko lākou komo ʻana i ka hana ʻana i ka hoʻokahe ʻia i ka papaʻaina. Ua hoomakau- 1.

ʻO nā mea momona e hoʻokaʻawale ana i nā kinikini a me nā momona (alpha-amylase, lipase) kahi i hūnā ʻia i ka hanana ikaika, nā enzyme proteolytic (trypsin, chymotrypsin, elastase, carboxypeptidase) i ke ʻano o ka proenzymes e hana ʻia ana i ka lumen o ka ʻōpū liʻiliʻi. ʻO ka enzyme intestinal, enterokinase, ka mea e hoʻohuli i ka trypsinogen i ka trypsin ikaika, noho i kahi nui o kā lākou hana. Hoʻokomo ʻia ʻo Trypsin i nā enzyme proteolytic.

Ma ke kaʻina o ka hoʻowalewale ana o ka lua, ua hāhaʻi ʻia nā kao (kākoi, glycogen) e ka pancreatic amylase e disaccharides a me kahi liʻiliʻi o ka glucose. Ma lalo o ka hana a nā proteolytic enzymes, ka peptides haʻahaʻa haʻahaʻa haʻahaʻa a me kahi liʻiliʻi o ka glucose e kūkulu ʻia. ʻO nā momona i mua o ka huahe i hoʻoliʻiliʻi ʻia e ka lipre pancreatic e di- a me ka monoglycerides o nā momona momona a me glycerol.

ʻO ka hana o nā enzyme pancreatic i ka neʻe ʻana i ka neʻe ʻana mai ka duodenum (duodenum) i ka pūlea eha. ʻO ka pae o ka emi ʻana o ka hana o nā enzyme o kēlā me kēia. No laila, lilo ka lipase i ka wikiwiki a i ka hana a ma ka ileum ua hoʻoholo like ʻia ma nā wahi liʻiliʻi. ʻO nā kumukūʻai, ʻoi aku ka amylase, ʻoi aku ka paʻa a mālama i ka 30% a me 45% o kā lākou hana i nā ʻāpana pahu o ka pūpū liʻiliʻi, kēlā me kēia. ʻO ke kumu o ka hoʻohaʻahaʻa ʻana i ka hana lipase ka mea i kona proteolysis ma lalo o ka mana o nā proteases a, ʻoi aku hoʻi ma mua o nā chymotrypsin. ʻO ka hoʻokaʻawale ʻana o ka hana o nā enzyme mai ka mea pili i ka ʻōpū liʻiliʻi liʻiliʻi e nānā pono ʻia i ka poʻe olakino a inā hoʻi, i ka poʻe me ka maʻi exocrine pancreatic incufficiency. E wehewehe kēia i ka ʻoiaʻiʻo o ka hala ʻole o ka hoʻowalewale ʻana o ka momona e ulu nui ma mua o ke kō a me ke protein.

Nā hoʻoponopono kānāwai huna

ʻO ka mea hūnā o ka pancreas he ʻelua mau ʻāpana - ductal (inorganic) a me acinar (organik).

Hoʻopuka ka hāno epithelium dīkene i kahi mea huna i nā electrolytes, keu loa nā bicarbonates, i ka hoʻohālikelike ʻana o ka hopena wai. ʻO ka hana o kēia māhele o ka hana huni o ka pancreatic ʻo ia ka pale ʻana i nā momona o ka gastric acidic e komo ana i ka duodenum a me ka hoʻololi ʻana o ka ʻili o ka ʻoki ʻana i loko o ka ʻōpū. ʻO ka mea hoʻonā nui o ka huna ʻana o ka māhele inorganic ka mea huna, i hoʻoili ʻia e nā S-cell o ka mucosa duodenal e pane i nā kūmole i ka makana mai ka ʻōpū.

ʻO ka pancreatic acinus glandulocytes ke kāpili ʻana a me ka huna ʻana i nā enzyme hydrolytic i lalo o ka mana o ka pancreosimine (cholecystokinin), i hoʻohuihui ʻia e J-mauʻu o ka mukosa duodenal. ʻO ka mea hoihoi no ka hoʻokuʻu ʻana i ka pancreosimine ka mea nui ka meaʻai.

ʻO ka maʻi a me ka nānā ʻana i nā pilikia o ka hoʻoweliweli o ka ʻōpū a me ka hana exocrine pancreatic

ʻO kekahi o nā hōʻailona mua o ka huina o ka hoʻopili ʻana ʻo ka steatorrhea. Loaʻa nā pīkī, ʻaila, clammy. ʻO nā mea maʻi me ka hoʻopiʻi nui ʻana o ka hana pancreatic exocrine e hoʻopiʻi nei i ka puhipuhi o ka maʻi, ka hoʻomohala ʻana i ke kinoea, ka ʻōpū o ke neʻe ʻana a me ke uha ʻana i ka ʻōpū. I nā pilikia koʻikoʻi nui aʻe, loaʻa ka polyphecalia, steatorrhea, nā maʻiʻeha a me ke kaumaha.

ʻO ke ala kūpono loa no ka hoʻopaʻa ʻana i ka lawa ʻole pancreatic exocrine ʻo ka hoʻoholo ʻana o ka pancreatic elastase-1 i loko o ka feces. ʻO ka hoʻomaʻamaʻa koʻikoʻi o ka hoʻoholo ʻana i ka fecal elastase-1 e ka immunoassay enzyme ʻo ia ka elastase-1 ka mea kūpono loa no ka pancreas, elastase-1 ka mea ʻaʻole i luku ʻia i ka wā e hele ana ma o ka ʻōpū o ka ʻōpū, nāʻaheʻe o nā hana stool elastase he mea nui ʻole, ka mea e hōʻoia i ka reproducibility kiʻekiʻe o nā hopena, ua hoʻoholo ʻia kēia ʻano wale nō kanaka elastase kanaka, no laila, ʻaʻole i hilinaʻi nā hopena hōʻike i ka hoʻomau ʻana o ka hoʻomehana enzyme hoʻololi.

ʻO ka hana maʻamau exocrine pancreatic i hoʻoholo ʻia me ka waiwai elastase-1 o 200 a 500 μg i 1 g o nā mea momona a ma luna, ke ʻano haʻahaʻa a me ka mālie - 100-200 μg / g, koʻikoʻi - emi ma lalo o 100 μg / g.

Ke hoʻoponopono ʻana i ka hoʻowalewale ʻana o ka ʻōpū luhi e nā enzyme pancreatic

Hoʻohana nui ka hoʻomākaukau ʻana o nā pāʻina Enzyme o ka pancreas e hoʻomaʻamaʻa no ka hoʻoneʻeneʻe ʻana o ka hana hāmeʻa pono ʻole.

Ua hoʻonohonoho ʻia nei nā lāʻau lapaʻau i manaʻo ʻia no ke hoʻololi ʻana i nā lāʻau e ʻae i kēia mau waiwai:

molelele kiʻekiʻe lipase,
ke kū'ē nei i ka wai momona
ka haʻalele wikiwiki ʻana mai ka ʻōpū a kāwili ʻia me ke chyme,
pahuhopu pōkole o ka microcapsule membrane i loko o ka pā liʻiliʻi,
ka hoʻokuʻu wikiwiki ʻana i nā enzyme hoʻoikaika i ka pā liʻiliʻi,
ka komo komo ʻana i ka hana ʻana o ka ʻōpū.

ʻO nā palapala Microgranular o ka hoʻomākaukau ʻana o ka enzyme e hoʻokō i kēia mau koi. ʻO ka microtablets Pancreatin me ka lōʻihi o ka 1 a 2 mm mm, kahi i kālai ʻia me ka pale o ka acid, kūkaʻi enteric, i waiho ʻia i loko o kahi māka gelatin. Hoʻomoe i loko o ka ʻōpū i loko o kekahi mau minuke, hoʻokuʻu ke kāpae i ka microgranules e kū mau ana i ka wai momona gastric no nā hola 2. Ua hoʻohui ʻia nā microgranules me ka chyme o ka ʻōpū a hoʻoiho ʻia i loko o ka ʻōpū liʻiliʻi, kahi a lākou e velea ai i ka ea alkaline, hoʻoiho i nā enzyme. No laila, ʻo ka hoʻomaka wikiwiki o ka hana o ka lāʻau i loko o ka pahu liʻiliʻi.

ʻO ka lipase ka wikiwiki o ka lula ʻana i ka hana ma kahi o steatorrhea. No laila, i ka hoʻoponoponoʻana o ka lawaiʻa pancreatic exocrine, ʻo ka mea mua, ua alakaʻi ʻia e nā kiko o ka lipase i ka lāʻau.

ʻO ka nui o ka microbe ka mea koʻikoʻi e hoʻoholo i ka wikiwiki a me ka manawa kūpono o kā lākou haʻalele ʻana mai ka ʻōpū. Pono ke anawaena o nā microgranules ka 1,4 mm 3.0 mm e hōʻoia i kā lākou huakaʻi kaulike me ka meaʻai ma o ka sphincter pyloric. Nā Mini-papa (2 mm i ka diameter, non-spherical shape) ʻaʻole hāʻawi i kahi wahi kūpono.

Hōʻike ʻia nā hiʻohiʻona o ka hoʻomākaukau ʻana o ka polyenzyme polygranular koʻikoʻi. 2 a me 3.

No ka hapanui o nā poʻe maʻi me ka hoʻohaʻahaʻa ʻana o ka hana pancreatic exocrine, ka lawe ʻana i ka 1-2 mau kapala (10,000-20,000 IU o ka lipase) me ka meaʻai ua lawa ia e hoʻopau ai i ka steatorrhea. I nā hoʻohālikelike koʻikoʻi o ka steatorrhea koʻikoʻi, hoʻonui ʻia ka nui o nā kapo i 4-5.

Ke koho nei i nā hoʻomākaukau o ka enzyme, e noʻonoʻo e noʻonoʻo i ka pae o ka elastase-1 i loko o ka palu (papaʻaina. 4).

Ua loiloi i ka hana pono o ka hoʻomākaukau ʻana i ka enzyme microgranular Mikrasima.

50 mau mea maʻi me CP me ka exocrine pancreatic insufficiency i nānā ʻia. Ua loaʻa he pūʻulu o nā mea maʻi 30 he Mikrasim 10,000 mau pūʻulu 2 mau mākeke 3 mau lā i kahi lā no 14 lā a he pūʻulu mana (20 nā mea maʻi) loaʻa iā Pancreatin 4 papa 3 mau manawa i kahi lā no 14 lā.

ʻO ka hopena holoʻokoʻa i loiloi ʻia e: haʻi, maikaʻi, hōʻoluʻolu, ʻaʻohe hopena. ʻO ka hana o ke ʻano o ka ʻeha, ka piʻi ʻana o ka neʻe ʻana o ka ʻōpū i loko, a me ka hana mau o ka ʻaʻa.

Ua hōʻike ʻia ka haʻawina e ʻoi aku ka ʻōlelo a Mikrasim ma mua o ka papa pancreatin, e pili ana i ka hoʻomaikaʻi ʻana i ka hoʻowalewale ʻana, hōʻemi ʻana i ka ʻeha o ka ʻōpū a me ka hoʻohaʻahaʻa i ka ʻaʻa.

Hoʻonui ka maikaʻi o ka hoʻomākaukau ʻana o ka enzyme me ka hoʻohui o nā mea antisecretory (H 2 -blockers, proton pump inhibitors) i ka hoʻomaʻamaʻa pancreatin maʻamau, ʻoiai ka hopena kūpono o ka enzyme pancreatic i ka wā i loaʻa ai ka pH i ka lumen o ka pōpoki liʻiliʻi ma mua o ka 5.0.

I nā kumu no ka pono ʻole o ka hili ʻana o nā ʻoihana hoʻonaninani:

ka pololei paʻa ʻana i ka maʻi (steatorrhea o ka non-pancreatic origin, giardiasis, celiac maʻi, nui nā mikrobial i ka ʻōpū liʻiliʻi),
ka haki ʻana i ka hoʻoponopono regimen (hoʻēmi i ka ʻoi ʻana o ka lawe ʻana i ka lāʻau, ʻai ʻana me ka meaʻai)
lawa ʻole hemahema o ka enzyme, nalowale o ka hana o ka lāʻau ma muli o ka mālama lōʻihi ʻole a mālama pono paha.
ka hana ʻole o ke kaʻina o ka waihona waikawa o ka ʻōpū.

Hoʻohālikelike

I nā makahiki i hala aku nei, ua ʻike nui ka nui o ka nui o nā maʻi pancreatic a, ma muli, me nā mea maʻi me ka exocrine pancreatic insufficiency e koi ana i ka hana hoʻokolo. ʻO ka hoʻohana nuiʻana o ka hoʻokolohua hou - ʻo ka hoʻoholo ʻana o ka elastase-1 i loko o nā feces i hiki ai ke hoʻomālamalama maikaʻi i ka maʻi excrine pancreatic a me ka loiloi i ka hopena o ka hoʻololi hou ʻana. Ua loaʻa ka nui o nā mākaukau no ka enzymatic me nā ʻano like ʻole o ka hana o ka enzymatic. Nā palapala i kēia mau lā, kahi i hoʻopili ʻia ai nā enzyme pancreatic i loko o ka microgranules (Pancytrate, Creon, Mikrazim) e ʻae e hoʻoponopono ʻia i nā pilikia ʻeha o ka hōʻemi.

Brooklis E.R. Ivashkin V.T. ʻO ka pancreatitis maʻi: etiology o pathophysiology a me ka conservative therapy // Ros. zhur. gastroen., hepatol., coloproct. 2006. Helu 6. S. 79-86.
Vinogradova L.V., Trubitsyna I.E., Gubina A.V., Chikunova B.Z. Ka ʻohiʻana o ka pancreatic hana a me kona hoʻoponopono ʻana ma muli o ke ʻano o ka maʻi pancreatitis // breast cancer. 2010. ʻAʻole. 13. S. 837-840.
ʻO Gastroenterology a me ka hepatology: hoʻomoʻi a me ka mālama ʻana. Puke no nā kauka / ed. A.V. Kalinina, A.F. Loginov, A.I. Khazanov. M .: Medpress-hoʻomaopopo. 2011.864 s.
Hubergrits N. B., Khristich T. N. ʻO ka pancreatology haukapila. Donetsk, 2002.413 s.
Kalinin A.V. Nā maʻi pancreatitis kūlike: ke nānā ʻana, ka mālama ʻana, pale ʻia // Kūlana ʻo Clinical. gastroen. hepatol. 2007. Helu 1. S. 37-40.
Mayev I.V., Kazyulin A.N., Kucheryavy Yu.N. ʻO ka maʻi pancreatitis kaha M .: Kauka, 2005.504 s.
Simonekov V.I., Poroshina E.G. Hoʻohana ʻokoʻa i ka hoʻohana ʻana i nā hoʻomaʻamaʻa papa o ka papa a me ka hoʻomākaukau ʻana i ka enzyme micronized // Consilium Medicum. 2011.S. 83-88.

A.V. Kalinin,Kauka i nā Kauka Kauka, Kauka

GU MONIKI lākou. M.F. Vladimirsky Keʻena Ola a me nā ʻOihana Aupuni o Russia, Moscow

- ka palena liʻiliʻi a i ʻole ka hana haʻahaʻa o ka enzyme pancreatic, e alakaʻi ana i ka hōʻeha a me ka lawe ʻana ʻana i nā meaʻai i loko o ka ʻawaʻawa. Hōʻike ia ʻo ia iho no ka lilo ʻana o ka nui o ka paona, flatulence, anemia, steatorrhea, polypecal, ʻeha a me polyhypovitaminosis. Hoʻokumu ʻia ka Diagnosis ma nā ʻano hana loea no ka hoʻopaʻa ʻana i ka mea huna o ka pankreas, ka lawe ʻana i kahi coprogram, e hoʻoholo ana i ke kiʻekiʻe o nā huina o ka huelo. Hoʻokomo ʻia ka hoʻomaʻemaʻe i ka mālama ʻana o ka maʻi mākaʻikaʻi, ka hoʻohālikelike o ka hoʻohana ʻana i ka mea kanu, ka hoʻololi o nā enzyme pancreatic, a me ka hoʻāʻo ʻana.

Nā huapau

ʻO ka mea nui no ka hoʻomaopopo ʻana i ka lawa o ka enzyme pancreatic he mau hōʻike kūikawā (kēnā a me ka loaʻa ʻole), pinepine pū pū me nā ʻano ultrasound, radiological a me endoscopic. ʻOi aku ke kumukūʻai ʻo Probe a hoʻonāukiuki i nā mea maʻi, akā ua ʻoi aku ka maikaʻi o kā lākou hopena. ʻOi aku ka maʻalahi o nā hoʻokolohua ʻole, ʻoluʻolu ʻia i nā maʻi nā maʻi, akā hiki iā lākou ke hoʻoholo i ka nele o ka pancreatic wale nō me ka hōʻemi nui a i ʻole ka pau ʻana o nā enzymes.

ʻO ka hoʻāʻo i ka mana huna secretin-cholecystokinin ke kumu gula no ka hōʻike ʻana i ka maʻi o ka enzyme pancreatic. Kuhi ʻia ke ʻano hana i ka hoʻoulu ʻia ʻana o ka mea huna pancreatic e ka luna ʻana o ka mea huna a me ka cholecystokinin, ukali ʻia me ka ʻike ʻana i kekahi mau kikoʻī o nā ʻike duodenal me kahi wana o 10 mau minuke. Ma nā kiʻi i loaʻa, ua noiʻi ʻia ka hana a me ka helu o ka mea huna o ka pancreatic, ka pae o nā bicarbonates, zinc, a me lactoferrin. ʻO ka maʻamau, ʻo ka hoʻonui ʻana ma ka nui o ka hilo ʻana ma hope o ka hoʻokolokolo he 100%, ʻo ka piʻi ʻana o ka nui o ka bicarbonates ma ka liʻiliʻi o 15%. ʻO ka hoʻonui ʻana i ka nui o ka mea huna o ka mea ma lalo o 40%, ʻo ka hala o ka hoʻonui ʻana i ka pae o ka bicarbonates, e ʻōlelo ana i ka nele o ka enzyme o ka pancreas. Hiki ke hopena maikaʻi nā hopena maikaʻi ʻole me ka mellitus diabetes, celiac maʻi, hepatitis, ma hope o ka haʻalele ʻana i kahi ʻāpana o ka ʻōpū.

Hoʻohālikelike ʻo ka loiloi o Lund me ka hoʻokaʻina mua, akā ua hoʻowalewale ʻia ka mea huna pioni e ka hoʻokomo ʻana i ka ʻai i ka ʻai. Maikaʻi kēia haʻawina e lawe (ʻaʻole pono i ka hōʻemi ʻana i nā lāʻau lapaʻau nui), akā ʻo kona mau hopena ke hilinaʻi nui ʻia i ka hoʻokumu ʻana o ka meaʻai hōʻike.Hiki ke hopena hopena maikaʻi inā loaʻa ka maʻi maʻi i ka maʻi mellitus, celiac maʻi, gastrostomy.

Hoʻokumu ʻia nā hana kumu ʻole me ka hoʻomaka ʻana o kekahi mau mea i loko o ke kino e hiki ai ke launa pū me nā enzymes i loko o ka urine a me ka hoʻokahe koko. ʻO ke aʻo ʻana i nā huahana metabola o kēia hoʻopili e hiki ai ke loiloi i ka hana exocrine pancreatic. ʻO nā hoʻokolohua ʻole i loaʻa ʻole iā bentiramide, pancreato-lauryl, iodolipol, triolein a me nā ʻano ala ʻē aʻe.

Eia kekahi, hiki ke hoʻokaʻawale ʻia ke pae o ka hiʻona pancreatic ma o nā hana kūlohelohe: ma ke ʻano o ke kao ʻana o ka plasma amino acid e ka pancreas, ma kahi ʻano kikoʻī o ka koprogram (nā kikoʻī o nā momona a me nā sabone e hoʻonui e kūʻē i kahi kūmole o nā pae maʻamau o ka waikawa momona), ka manaʻo kuʻuna o nā feces, fymal chymotrypsin a me nā trypsin 'elastase-1.

ʻO nā hana diagnostic instrumental (radiography o ka ʻōpū o ka ʻōpū, MRI, CT, ka ultrasound o ka pancreas a me nā ʻōnaehana hepatobiliary, ʻo ERCP) i hoʻohana ʻia e ʻike ai i nā maʻi lalo.

ʻO ka mālama maikaʻiʻana o Enzyme

Pono e mālama i ka hoʻōla ʻana o ka pancreatic exocrine, me ka hoʻoponopono ʻana i ke kūlana o ka nutritional, etiotropic a me ka hoʻololi hou ʻana, ʻo ka hōʻailona hōʻailona. Hoʻokomo nui ʻia ka lāʻau Etiotropic e pale i ka holomua o ka make o ka parenchyma pancreatic. Ke hoʻoponopono ʻana i ka ʻai ʻai ʻana i ka hoʻopau ʻana i ka hoʻohana ʻana i ka wai ʻawa a me ka uahi o ka paka, e hoʻonui ana i ka nui o ka protein i loko o ka meaʻai i 150 g / lā, e hōʻemi ana i ka nui o ka momona ma kahi o ʻelua mau kaila o ka physiological, a me ka lawe ʻana i ka mau huaora i nā lāʻau lapaʻau. Me ka hōʻemi nui ʻana, pono paha kahi kīnā makua a palūʻau piha.

ʻO ke ʻano nui no ka hemahema o ka hoʻoulu ʻana o ka pancreatic i ke ola o ke koina ʻana o ka huina o nā enzyme me ka meaʻai. Nā ʻōmai no ka hoʻoliʻi hoʻololi ʻana o ka enzyme no ka lawa o ka pancreatic: steatorrhea me ka nalowale o ka nui o 15 g o ka momona ma ka kikeke, ka holomua ʻana o ka protein-ikehu.

ʻO ka hoʻomākaukau ʻana no ka enzyme Microgranular i loko o kahi kinikona pale pale i hoʻopuni ʻia i loko o kahi capsula gelatin ka mea koʻikoʻi loa i kēia lā - pale ka capsule i loko o ka ʻōpū, hana i nā ʻano no ka hoʻohuihui like ʻana o nā granule lāʻau me ka meaʻai. I ka duodenum, i ka hiki ʻana i ka pH o ka 5.5, ua hoʻokuʻu ʻia nā manaʻo o nā grala, e hāʻawi ana i kahi kūpono o ka enzyme pancreatic i loko o ka wai duodenal. Koho ʻia nā Dosis o nā lāʻau lapaʻau ʻokoʻa, e pili ana i ka nui o ka maʻi, ka nui o ka ʻaila pancreatic. ʻO nā mākaʻai no ka hana o ka hoʻololi hoʻololi ʻana a me ka lawa o nā kaha o nā hoʻomākaukau ʻana o ka enzyme ʻo ia ka loaʻa ʻana o ka paona, i hōʻemi ʻia e ka lemule, a me ka hana maʻamau.

ʻO ka wānana a me ke kālai

ʻO ka prognosis no ka pihaʻana o ka pancreatic ma muli o ka nui o ka maʻi i lalo a me ka piʻi o ka hōʻino o ka pancreatic parenchyma. Kuhi i ka manaʻo o ka nele o ka enzyme pancreatic i hoʻomohala me ka make o kahi ʻāpana koʻikoʻi o ka huelo, maʻamau ka prognosis. Hiki ke pale i ka hoʻomohala ʻana o kēia ʻano ma ka manawa kūpono a me ka mālama ʻana i nā maʻi pancreatic, hōʻole i ka inu ʻawa, a me ka uahi.

Hoʻomaopopo ka ʻeha o ka pancreatic insufficiency (ma aneʻi i ʻōlelo ʻia ʻo ka pancreas pōkole) i ka ʻeha o ke kaumaha i loko o ka ʻōpū (maʻamau mau ʻia he mau hola ma hope o ka ʻai ʻana i nā meaʻai momona), a me ka puʻuwai puʻuwai, nā iwi a me nā mea ʻē aʻe he nui e kūkākūkā ʻia ma hope aʻe o ka ʻatikala.

ʻO ka pancreas ka mea nui i ke kino o ke kanaka, a me nā hōʻailona like like e hōʻike ana i ka pau ʻana o ka hana maʻamau.

Hiki i kēia ke alakaʻi i ka holoʻokoʻa o nā pūnaehana kino a pau.

Hoʻopau ʻole pancreatic

E like me nā mea āpau a pau, pancreatic insufficiency he mau kumu.

ʻO kēia ʻenehana o ka digestive ka nui o ka nui o ke kino o ke kino, kahi lōʻihi e hiki ke hana "no ka lole", a i ka manawa like ʻaʻole e hāʻawi i nā hōʻailona o ke kuʻukahi.

Loaʻa nā pancreas i nā hana endocrine a exocrine.

Me kā lākou kōkua, hiki i ke kino ke hoʻoponopono i nā kaʻina metabolic i loko o ke kino a hoʻoulu i nā enzyme digestive e kōkua i ka hōʻoki ʻana i nā ʻāpana paʻakikī i ka meaʻai i loko o ka ʻōpū.

Inā pau ka pancreas i kekahi kumu i ka huna ʻana i ka wai pancreatic i loaʻa i nā kinipuna digestive, a laila paʻa ka pancreatic.

ʻO ka papa inoa o nā kumu nui e haunaele ai i ka hana o ka kūwili ʻana e kū nei:

loli nā ʻano helehelena i nā aea,
nā hemahema o nā huaora o ka pūʻulu B, mau huaora C a me E, ka waʻo nikotinic,
ka haʻahaʻa haʻahaʻa o ka protein a me ka hemoglobin i loko o ke koko,
ʻAi ʻia ka momona, momona palua a me ka ʻai paʻakai.

Hiki i ka ʻōnaehana o ka papa ke hōʻoki i nā loli pathological no ka hoʻohana ʻana i nā mea inu ʻaka. ʻO ke hopena, ua hoʻololi ʻia nā ʻili o ke kino i nā kiko pili, e hoʻonele ai i ke kino holoʻokoʻa.

No ka laʻana, hiki ke oki ka hao i ka hoʻoulu ʻana i nā insulin, pono ke kino e komo i ka glucose. E like me kāu e ʻike ai, ma muli o kēlā hōʻino ʻole, lilo ke kanaka i ka maʻi maʻi maʻi.

Eia kekahi, hiki ke hoʻopili ʻia ka pili o ka gland i ka maʻi, ka hoʻouluulu helminthic a me nā maʻi collagen.

Akā ʻo nā ala āpau maʻamau e loaʻa i ka hopena nui i ke kūkulu ʻana i nā kiko o nā huina o ka huina a nā maʻi pancreatitis a me ke kūpaʻa pancreatitis.

ʻO nā huaora o ka hui B e hana i kahi hana koʻikoʻi i ke kāpili o nā enzyme digestive, me ka ʻole o ka ate ke oki i ka hana maʻamau.

Inā kūmole ka huna ʻana o nā enzyme a bile i loko o ka duodenum 12, a laila ʻaʻole kūleʻa ke kaʻina holo ʻana.

Me ka emiʻole o ka pancreatic, nā huaora o kēia hui e komo i ka lāʻau lapaʻau. ʻO ka hemahema o ka waikawa Nicotinic (B 3 a i ʻole PP) ke hōʻemi nei i ka emi ʻana o ka trypsin, amylase a me ka hana i ka lipase.

ʻO kahi hemahema o nā huaora C a me E e hana ai i nā gallstones e hana.

I waena o nā kumu nui e loaʻa ai i kahi kanaka kuhi i ka hana o ka pancreas, aia kahi predisposition hoʻoilina.

I kēia hihia, ʻaʻole hiki ke hōʻoiaʻiʻo ʻia kahi maʻi e ʻike ʻole ʻia.

ʻO ka paleka pancreatic hiki i nā ʻano ʻehā: exocrine, exocrine, enzymatic a me endocrine.

ʻO kēlā me kēia ʻano me ke ʻano kumu o kēlā me kēia hanana, nā hōʻailona pili i ka hanana a me nā hiʻohiʻona mālama, e kūkākūkā ma lalo nei.

Ka hemahema a exocrine a exocrine

Hoʻohana ka huaʻōlelo ʻo exocrine pancreatic insufficiency i loko o ka hana lapaʻau me ka hoʻohaʻahaʻa ʻana i ka hana huna pancreatic, kahi i hāʻawi ʻia i ka wāwahi ʻia o nā mea ʻai paʻakikī i nā mea maikaʻi, a laila e hoʻopili koke ʻia e ke kino.

Hōʻike ʻia ka hōʻemi ʻana o ka hana o ka hoʻoneʻe a me ka hoʻohaʻahaʻa ʻana i ka nui o nā puna i ka pancreas e kuleana ai ka hana ʻana.

Hiki ke hoʻopili ʻia nā hōʻailona o ka lawa o nā exocrine i nā hōʻailona kikoʻī, no ka mea, me kā lākou kōkua me e hiki ke hoʻomaʻamaʻa i kēia ʻano ʻano pili.

I kēia hihia, ʻaʻole ʻaeʻae kekahi kanaka i nā meaʻai momona a momona, me ka mea ma hope o ka ʻai ʻana, wawahi ka ʻaʻa a no ka manawa lōʻihi ka manaʻo o ke kaumaha i loko o ka ʻōpū.

I kekahi poʻe me ka exocrine pancreatic insufficiency, colic a me bloating e loaʻa.

Hoʻohui pinepine, ʻo kēia mau hōʻailona me ka ʻike ʻana o ka ʻeha ma ka iwi a me nā mea hoʻohālikelike, ka hiʻohiʻona o ka pōkole o ka hanu a me ka puʻuwai wikiwiki.

Hōʻike kēia mau maʻi āpau ma muli o kahi hemahema o nā palaka i hikiʻole ke hoʻokomo ʻia e ke kino, akā he mea koʻikoʻi loa ia no ka hana maʻamau.

I waena o nā kumu maʻamau o ka exocrine dysfunction ʻo ka emi ʻana o ka hana o ka nui cell exocrine a me ka hūnā ʻia i ka duodenum.

Ke mālama nei i kēia ʻano o ka palaka pancreatic e pili ana i ka mālama ʻana i ka ʻai meaʻai a me ka hoʻohana ʻana i nā lāʻau lapaʻau e hāpai ana i ka hana pancreatic (Mezim, Pancreatin).

Hoʻopilikia ʻia nā maʻi pancreatic Exocrine me ka nele o ka wai pancreatic, ka mea i hāʻawi i ka hana maʻamau a paʻa i ka hana gastrointestinal.

Hoʻomaʻamaʻa nā hōʻailona o ka hana o ka exocrine i ka hoʻokaʻawale ʻole ʻana o ka gastrointestinal tract, ka ʻike i ke kaila a me ke ʻano kaumaha i loko o ka ʻōpū. Ke hele pū nei nā mea āpau a pau me ka waikawa a me ka palekikena.

Nā kumu i loaʻa ai i kahi kanaka ka lawena pancreatic exocrine i hōʻemi ʻia i ka hōʻino ʻana o ka ʻōpū, ka ʻōpū ʻana a me ka duodenum.

I ka huli ʻana, hiki i ka hana ʻole o nā hana o kēia mau mea kūlohelohe ke hiki ke kū i ka hope o ka pōloli, ka hoʻohana pinepine pinepine ʻana i nā mea inu wai a me nā meaʻai kūpono.

Ka huina o ka exocrine exocrine e hoʻohana ana i nā hopena o nā hōʻike koko lapaʻau.

Pono e hoʻomaopopo ʻia he pili nui ka poʻe me kēia ʻano o ka pathology i ka hoʻomohala ʻana i ka maʻi diabetes, no laila ua ʻōlelo pinepine ʻia lākou e hāʻawi i koko i ke kō.

Hoʻomaʻamaʻa ka hoʻomaʻamaʻa ʻana o nā hana exocrine e hoʻopau i ke kumu o ka maʻi, e hele ana ma ke ʻano o kaʻai ʻana, ka lawe ʻana i nā huaora a me nā lāʻau lapaʻau e kōkua ai e hana i ka wai pancreatic.

ʻO ka hemahema a me ka hoʻopauʻana o endocrine

Hōʻike ʻia ka ʻōpū o ka Enzymatic pancreatic me ka hapa ʻole o ka wai pākēnē o kekahi ʻano ʻano o ka digestive enzyme, e kōkua ana i ka ʻai ʻana i ka ʻai.

ʻO nā kumu nui o ka hemahema o ka enzyme e hōʻike ʻia

kahi loli pathological i loko o nā puna o ka pancreas, ka mea e hiki mai ana no ka lōʻihi o ka hōʻike ʻana i nā antibiotika a me nā mea ʻai ʻē aʻe,
poino i ka kūmole pancreatic (hoʻonui ʻia i ke kaʻo Wirsung),
kalena
maʻi ʻia e nā maʻi.

Nā hōʻailona ʻuhane e loaʻa ana i ke kanaka kahi palekana enzymatic o ka pancreas e hōʻike ʻia e nā hōʻailona e like me nā mea i hele mai i ka wā ke hewa ka hana i loko o nā ʻāpana.

ʻO ka mea mua, he mea palaki kēia o ka ʻaʻa, e hōʻike pinepine ʻia e nā maʻi maʻi, e hōʻailona ʻia e kahi ʻano fetid.

E pale aku i ke kua o ka maʻi lōʻihi, ʻike ka poʻe i ka dehydration a me ka nawaliwali ākea. ʻO ka hemahema o ka makemake a me ka puka ʻana o ka maʻi pāheʻe e hele pū me ka hoʻonui ʻia ʻana o ka wahi a me nā hōʻeha a me nā ʻeha hōʻeha i loko o ka ʻōpū.

Hōʻike ʻia ka hemahema o Enzymatic e hoʻohana ana i nā hopena o ka hōʻike koko maʻamau a me ka biochemical, urinalysis a me nā feces, e hoʻohana ana i ka tomography a me ka ultrasound.

ʻO ka mālama ʻana i kēia ʻano o ka papaʻaina e pili ana i ka hahai ʻana i kahi papa i kau ʻia e ke kauka a kau i nā lāʻau lapaʻau i hiki ke hāʻawi i ke kākoʻo pono no ka pancreas.

ʻO ka endocrine (intrasecretory) pancreatic insufficiency ka mea i hōʻemi ʻia e ka hoʻokaʻawale ʻana i nā hana o nā hormones, e hui pū me ka insulin, glucagon a me lipocaine.

ʻO kēia ʻano ke ʻano o ka pathology ka mea maikaʻi loa loa, no ka mea hiki ke hoʻopiʻi i nā hana kūlohelohe i loko o ke kanaka.

ʻO ke kumu nui no ka emi ʻana o ka hana o kēia mau makeneka e iho mai ana i ka pōʻino i kēlā mau wahi o ka pancreas e kuleana ai no kā lākou hana.

Hōʻike nā hōʻailona o nā maʻi intrasecretory iā lākou iho e like me ka wehe ʻana o ka pae o ka hormone i nā hopena o nā hōʻike koko.

Hoʻopili ʻia kēia ʻano me ka hoʻonaninani pinepine ʻana i ka wai pīpī a me ka ʻilekō, kahi i mālama ʻia ai kahi momona fetid.

E pale i ke kua o ka hoʻonui o ka nui o nā neʻe o ka ʻōpū, kū ʻia ke dehydration, kahi e hōʻalo ai i ka nāwaliwali ākea.

Hoʻopau ʻia me ka pathology pancreatic endocrine ma ke ʻano like o ka hikiʻole i ka enzymatic.

Hoʻokomo ʻia ka papaʻai i ka papa e kuhikuhi ana i ke kaohi ʻana i ke kōpaʻa koko a mālama i nā lāʻau lapaʻau i kuhikuhi ʻia no kēlā me kēia maʻi.

Hana ka pancreas i nā hana nui i loko o ke kino e hōʻoia i ka hana maʻamau o ke kino. E like me kekahi hoʻolālā intraorganic, hiki i ka pancreas ke hōʻeha i kekahi hopena pathological, ʻo ia ke kumu e hōʻemi ai kāna hana. ʻO kekahi o kēia mau kūlana no ka palaka hao pancreatic.

He kumu no ke kūkulu ʻana

Hoʻomaʻamaʻa ka pancreas i ka hana ʻana o nā enzyme digestive kūikawā, me ka ʻole o ka hiki ʻole o ke ʻano o nā hana kaomi kūloko.

Ke hana ʻole ia ka hana ʻana i kēia mau mea a hoʻomaka ka hao i ka hana haʻahaʻa, a laila kāhea ʻia kēia ʻano me ka maʻi pancreatic.

Aia he nui nā kumu o ka palaka pancreatic. E pili ana kēia:

ʻO ka hapa o nā huaora
Ka pōʻino i ka pancreas
ʻO ka hapa hemoglobin
ʻO ka hapa o ka protein i ke koko,
ʻAno ʻole e pono ai, ka hōʻino ʻana i ka ʻai paʻakai, nā mea momona, nā mea ʻala, nā mea ʻala, a,.
ʻĀpilima
Nā alahele e like me lipomatosis, cystic fibrosis, Schwachmann syndrome,
ʻO ka make ʻana o nā kelopa kelepona ma ke kua o ka pancreatitis a i ʻole ke kaʻe ʻana o ka ʻāpana o kahi ʻoai.

I kekahi manawa aia kekahi mau mea e hoʻonāukiuki i ka hoʻomohala ʻana o ka pathology. A eia paha, ua like ka mea maʻi me ke olakino, mālama ka ola kino, ʻai ʻiʻo, akā ʻike mau ʻia ka pancreatic. I kēlā mau kūlana, maʻamau nā kumu i waiho ʻia ma kahi predisposition he nui.

ʻO nā ʻano maʻi o nā maʻi: nā kumu, nā hōʻailona, nā maʻi a me nā hana lapaʻau

Hoʻololi ka poʻe loea i nā ʻano ʻehā like ʻole o ka pancreatic function insufficiency, kēlā me kēia nona ke kūlana, ʻoi aku a hiki i ka etiology a i ʻole nā ʻano mālama.

ʻO ka ʻāpana pancreatic paha:

Hoʻolālā
Hoʻolālā
Hoʻoulu
Endocrine.

ʻOiai no kēlā me kēia ʻano like ʻole o ka ʻokoʻa ʻē, a laila pono lākou e noʻonoʻo kaawale.

ʻO ka palupalu pancreatic Exocrine

Kahi lawaiʻa pancreatic exocrine i kapa ʻia he pathology kahi i loaʻa ʻole ka waiʻai no ka papa paʻa o nā hana digestive. ʻO nā hōʻailona ʻehā o ia ʻaihā pancreatic ʻo:

Nā hopena maʻi
Lūlū
ʻO ka manaʻo o ke kaumaha i ka epigastrium,
Nā pilikia Stool
Hoʻopule maikaʻi ʻole.

ʻO nā pilikia ʻeha āpau a me nā pancreatic pathologies ma muli o nā loli i nā kōpili kūloko ma mua o kēia ʻano pathological. Eia kekahi, hiki i ka exocrine insufficiency hiki ke ulu kūʻē i ke anuanu o ka gallbladder a i ʻole nā maʻi ʻeha, ka momona nui a i ʻole hōʻino paha a me nā mono-diets.

Hiki ke ʻike ʻia ka hemahema o Exocrine ma o ke ʻano ʻana o ka loaʻa ʻana o ka maʻi makana. Me kēlā mau pancreatic kīnā, ʻo ka nui o ka ulu ʻana o ka hoʻomohala ʻana i ka maʻi diabetes, no laila pono e nānā mau kēia mau mea i ka lolo koko.

ʻO ka kūleʻa o ka hoʻomaʻamaʻa pololei ʻana i ka hoʻokumu pono ʻana o ka etiology o ke kaʻina pili. Me ka mea eʻai ai i ka wai a i ka wai inu paha, pono ʻoe e loli i kou nohona ma o ka haʻalele ʻana i ka meaʻai me nā inu ʻona.

Ma kaʻai ʻai me kekahi ʻano like ʻole o ka nele o ka hao pancreatic, pono nā huaora e like me ka ascorbic acid, tocopherol a me ka retinol.Hoʻohui, ua hoʻonohonoho ʻia nā hoʻomākaukau enzymatic i nā maʻi e kōkua i ka kelepona e hoʻokō i ka hana huna.

Endocrine

ʻO kekahi ʻano ʻē aʻe o ka pancreatic insufficiency i manaʻo ʻia he endocrine a i ʻole intrasecretory.

ʻO nā hana nui o ka hana endocrine ka hana ʻana o nā mea hormonal e like me ka glucagon, lipocaine a i ʻole insulin. Inā hele ʻole kahi hana i kēia hana, a laila hikiʻole i nā hopena o ke kino ke hoʻohuli.

Hoʻohālikelike ʻia kahi ʻano like ʻole o ka hemahema e pili ana i ka wā o nā lepa o kēlā mau pūnaewele hiʻona (islets of Langerhans) e kuleana no ka hana ʻana i kekahi ʻano hormonal. Me kēlā mau lehelehe, he hoʻoweliweli aneʻi pinepine ʻia e ka maʻi maʻi ma luna o ka mea maʻi.

Hōʻike ʻia ka lawa ʻole pancreatic Endocrine e nā ʻano like me:

Pole o nā mea ʻea i hoʻokuʻu ʻia,
Nā hopena pane
Hoʻopili a kuʻi hoʻi i ka puhipuhi fetid.
ʻO ka hoʻonui ʻia ʻana o nā wahi o ka bowel,
Hōʻike nā hōʻike koko Laboratory i ka heleʻana o nā mea ponoʻole.

Eia kekahi, aia kekahi mau hōʻailona o kahi ʻano concomitant, e like me ka malaise maʻamau o ka mea maʻi e kū kūʻē i ka kiʻi o ka dehydration no ka maʻi ʻana.

Hoʻohālikelike ʻo ka hoʻāhu ʻana me nā ʻano ʻē aʻe o ka nele o ka pancreatic.

Ma hope o ka hoʻokau ʻana i kahi maʻi kūpono, ua kuhikuhi ʻia ka mea maʻi i ka ʻoi loa ʻoi aku ka lāʻau e makemake ʻia e hōʻemi i ka glucose i loko o ke koko. Inā ʻaʻole pono nā meaʻai meaʻai, ua kau ʻia nā inikena insulin.

Hiki iā ia ke ola me kēia ʻano o ka hoʻopukapuka, akā, ʻo kaʻai ʻoi loa ka lilo ʻana i ke kumu me ka ʻole o nā ʻokoʻa a i ʻole nā indulgences.

Wahi a nā helu helu, ʻoi aku ma mua o 30% o ka heluna he mau ʻano o ka nui o ka pancreatic insufficiency. Ua ʻike kekahi ma ke ʻano o kā lākou helehelena a ua hana mua ʻo ia i nā hana e hoʻopau ai, ʻoiai ua naʻaupō kekahi, ke hoʻomāhuahua wale nei ke kūlana.

ʻO ka mea nui, ma ka loaʻa ʻana o kekahi mau pancreatic insufficiency, e hahai ikaika i nā ʻōlelo hāʻawi ʻana i ka meaʻai a lawe i nā lāʻau i kuhikuhi ʻia e like me ke kumumanaʻo i kuhikuhi ʻia.

ʻOiaʻiʻo, kahi pili like ʻole no kekahi kanaka e pili pū me nā manaʻo like ʻole, akā inā haʻalele ka mea maʻi i nā hana maikaʻi ʻole a me ka meaʻai maikaʻi ʻole, a laila e holomua ka maikaʻi o ke ola a kāpae ka maʻi.

Inā loaʻa ka mea i kūʻē i ke kua mua o ka waiʻona i hiki ke hopu i ka pancreatic, a laila me ka hōʻole loa ʻana i ka inu ʻona, hiki iā ia ke ola hou 10 mau makahiki.

Akā, inā hoʻomau ka hoʻomanawanui i ka inu ʻona a ʻai i nā meaʻai i pāpā ʻia, a laila ma hope o kekahi mau makahiki i lilo ai ia. No laila, ʻo ka HLS a me ka meaʻai me ka like me nā maʻi like ʻole, ʻaʻole ia ke maʻi o ke kauka, akā ke kī i ka mālama ʻana i ke ola.

Video e pili ana i ka lawa ʻana o ka pancreatic exocrine:

- He hui koʻikoʻi nui kēia i nā kānaka. Hana ia i nā hana he nui e hōʻoia i ka hana maʻamau o ke kino. E like me nā meaola ʻē aʻe, hiki i ka pancreas ke malfunction. ʻO kekahi o nā maʻi maʻamau loa ʻo ka maʻi pancreatic.

Nui a hewahewa nā ʻano pancreatic insufficiency

E like me nā maʻi āpau ʻē aʻe, loaʻa kēia nā kumu i kūloʻe ai kēia hemahema. I loko o ka pancreas, hana ʻia nā enzyme kūikawā, me ka ʻole o ka maʻalahi o ke kaʻina hana ʻana.

hiki iā ia ke ola e pili ana i 10 mau makahiki Inā hele mai kahi malia i ka hana ʻana o kēia mau enzymes a me nā mea, a laila ua kapa ʻia kēlā me ka maʻi ʻano i kapa ʻia ʻo pancreatic insufficiency. Ma waena o nā kumu kumu e hiki ai i kēia hana ke hoʻomaopopo:

Hana ʻinoʻino i ke kiko pancreatic
ʻO ka pohō o nā huaora ma ke kino
Hoʻemi ka nui o ka nui o ka wai protein
Hoboglobin haʻahaʻa
ʻO kaʻai kūpono kūpono, i ka hoʻohana ʻana i nā mea momona a me ka paʻakai, ka hoʻohana ʻana i nā mea ʻala ʻole a me nā mea ʻē aʻe.

ʻOiaʻiʻo, ʻaʻole kēia nā kumu āpau no ka hiki ke hoʻokumu ʻia o ka maʻi pancreatic. Aia kekahi nui o nā kumu. I kekahi manawa hiki i ka moʻomeheu (predisposition) ke hana i kahi kūlana koʻikoʻi. ʻO kahi mea ke alakaʻi nei kekahi kanaka i kahi ola maʻamau, ʻai maikaʻi, me ia, akā, e hoʻomau ʻia naʻe i kēia maʻi.

Nā ʻano o ka paʻa pancreatic

I kēia lā, aia ʻehā mau ʻano o ka piha o ka pancreatic function. Hoʻokahi ʻano ʻano like o kēlā me kēia ʻano ʻano, e hoʻomaka ana i nā kumu o ka helehelena, e pau ana me nā hōʻailona a me ka mālama ʻana. No laila, hoʻokaʻawale:

ʻO ka hemahema ʻo Exocrine
ʻO ka hemahema o Exocrine
ʻO ka hemahema ʻo Enzyme
Hoʻopau maikaʻi Endocrine

E like me ka mea i hōʻike ʻia ma luna, i kēlā me kēia me kona ʻano like. No laila, i ka hoʻomaopopo pihaʻana i nāʻokoʻa a he like paha a he ʻano pae like paha ma ka hōʻike ʻana i nā hōʻailona, pono ʻoe e ʻike pono i kekahi. ʻAʻole maikaʻi loa kahi piha o ka pancreatic. Akā i ka mea e hoʻokūpaʻa ai i ke ʻano o ka piha o ka wahi ʻole e pono ai, pono ʻoe e kamaʻilio i kahi kauka nāna, i hoʻokumu i kēlā mau maʻi, e hana i kahi maʻi kūpono a kuhikuhi i ka hana kūpono.

ʻO ka hemahema ʻo Exocrine

I ke kaumaha, i kēia lā a nui loa e loaʻa i ka poʻe i ka maʻi o ka pancreatic sector. A inā ma mua o ka hoʻomaka ʻana o ka helu umauma ma kahi o 50 mau makahiki he nui wale, i kēia lā ua neʻe nui ka pae, a me ka poʻe o ka wā ʻōpio ua ʻeha ia. ʻO ka nele o nā mea huna pilikino me ka nele o nā enzymes (laikini), no ka mea ke kahaha o nā mea waiwai a pau i ke kino. Hana kēia no ka mea, i ka manawa, ma lalo o ka mana ikaika o kekahi mau mea i ka pancreas, ka nui o nā pūpū e hana ai i kēia mea huna koʻikoʻi.

E like me nā maʻi ʻē aʻe, ʻo ka hemahema o ka exocrine ka nui o nā hōʻike, e hiki ai ke hoʻoholo i kēia ʻano ʻāpana. I waena o nā hōʻailona nui:

Ke hoʻomanawanui ʻole nei i ka ʻaila a me nā meaʻai anuanu. He mea paʻakikī loa ia no ka poʻe me ka nele ʻole o ka ʻai ʻana i nā meaʻai momona, ʻoiai he mea paʻakikī ʻole ke hoʻokaʻa a ʻike ʻole ʻia e ke kino.
He kaumaha ma ka ʻōpū. Hoʻokumu ʻia ia ma hope o ka ʻai ʻana o kahi mea ʻai i ka mea momona, ka mea, e like me ka mea i ʻōlelo ʻia ma luna nei, ʻaʻole i komo e ke kino.
Laulau momona. ʻOiai he mushy ia
Kahi
Nā ʻeha iwi

Ma waena o nā mea ʻē aʻe, nā hōʻailona o ka hōʻike o ka exocrine insufficiency hiki ke hoʻohui pū i ka palpitations naʻau, nā ʻūheʻaka, ke pōkole o ka hanu, nā hōʻino i loko o ka coagulation koko, ke kino maloʻo, etc. Hōʻike kēia mau hōʻailona ma muli o ka loaʻa ʻole o ka momona o ke kino, ʻo ia nō ka mea nui loa. Ma muli o ko lākou emi haʻahaʻa, ala ʻia nā pilikia concomitant e loaʻa ai ka ʻehaʻeha ma mua o nā hōʻailona pololei o ka hōʻike o ka maʻi.

Aia kekahi mau kumu kikoʻī e hiki ai i ke kanaka ke kūkulu i kēia ʻano o ka hana ʻole. E pili ana kēia:

ʻO ka hōʻemi ʻana i ka nui o ka parenchyma exocrine
Ka puka ʻana o ka mea huna i ka duodenum
ʻAʻole lawa ka komo ʻana o nā enzymes i ka hoʻoili ʻana i nā mea kinona

ʻO ka ʻoiaʻiʻo, ʻo ka mālama nui ʻana ka mālama ʻana i kahi meaʻai kūpono, nā loina kumu ʻo ia hoʻi ka ʻōlelo ʻana:

Pono e hoʻonui i ka helu o ka papaʻaina, ʻoiai e hōʻemi ana i kona helu
Hoʻopili i ka hoʻohana ʻana o nā mea momona momona, a hiki pū nō hoʻi me nā ʻaina momona āpau
E kaupalena i ka inu ʻana i ka meaʻai i ke ahiahi a me nā hola ahiahi
Pono e haʻalele loa

Ke kūkā ʻia nā huahana e ʻae ʻia e kūkākūkā me ke kauka komo, nāna e ʻohiʻohi i ka ʻai ʻana o ka mea maʻi.Inā mākou e kamaʻilio e pili ana i ka pākuhi i ka papa o nā momona a me nā meaʻai holoholona, a laila e pono e hoʻololi i ia me ka laulala, ʻo ia hoʻi, e ʻai nui i nā lau a me nā huaʻai. Ke kī mua nei no ka poʻe e loaʻa ana i kēlā maʻi like ʻole, e puka mai nā huehue, pono e hoʻopau ʻia i ka nui kūpono e kōkua ai i ke kino. Akā he mea kūpono e hoʻomanaʻo i ka mea nui e pono ai ʻoe e nānā i nā huapalapala i ka meaʻai olakino, ʻaʻole hoʻi i loko o nā ʻono, kahi e pili ai ka hāmeʻa i ka nui.

Akā aia nō kahi hoʻokahi ana i kēia mau mea a pau, i kēia meaʻai holoʻokoʻa. Nui nā poʻe maʻi e hoʻohuli ʻokoʻa i ka meaʻai kanu e hoʻomaka i nā pilikia e pili ana i ka hoʻomohala ʻoli. Inā hele kēia, a laila e aʻo ʻia e nā maʻi e ʻai i ka bran.

Hoʻopili i nā mea ʻai, ua kuhikuhi ʻia nā mea maʻi i nā lāʻau e kōkua pololei i ka pancreas. Ke loaʻa nei kēia mau lāʻau iā Creon, Pancreatin, Mezim, etc. ʻO ka maʻamau, ua kuhikuhi ʻia kēia mau lāʻau ʻana me kēlā me kēia pāʻina i ka haʻalele ʻana i nā pilikia o ka hiki ke hōʻalo.

ʻO ka hōʻailona nui o ka pololei o ka hoʻomaʻamaʻa ʻia ʻana ʻo ka nalo ʻana o ka maʻi maʻamau, a me nā hōʻailona maʻamau i nā feces o ka mea maʻi. He pilikia paʻakikī ka Exocrine pancreatic, akā hiki ke noho pū me ia. Pono wale ʻoe e nānā i kāu meaʻai a hahai i nā ʻōlelo a ke kauka a pau.

ʻO ka hapa Enzyme Pancreatic

ʻEha e like me kekahi o nā hōʻailona o ka maʻi pancreatic

Hana ke pancreas i kekahi mau hana o kekahi mau hana, a me kekahi o kāna ponoi e hoʻonāukiuki i ka hoʻomohala ʻana i ka lawa ʻole. ʻO kekahi o nā insufficiencies pancreatic maʻamau ka enzymatic. komo i loko o ka wai momona a kōkua i ka hoʻokahe ʻana i ka meaʻai. Inā kū ia ma ka liʻiliʻi loa ʻaʻole hoʻokahi o nā enzyme i ka nui o ka nui, a laila e hoʻopau ʻia ke kaʻina hana.

Ma waena o nā kumu o ka hemahema o ka enzyme e hiki ke hoʻomaopopo ʻia:

Hana ʻino i nā cell pancreatic ma lalo o ka mana o kekahi mau lāʻau
Nā maʻi maʻi
Hoʻopilikia i nā hana dure no ka pancreatic
Nā ʻōiwi i ke ʻano o ke kumumea (congenital)
ʻO ka Dysbacteriosis

I waena o nā mau hōʻailona i hōʻike i ke kaohi o ka enzyme, hiki ke hōʻike ʻia kēia aʻe:

Heʻa e hoʻoneʻe, i nā kīwaha wehe
Nā nāwaliwali nui
Makemake ʻia
Hoʻonui ka mīkini hana
ʻO ka uku kaumaha a me ke kino pilikino o kahi kanaka
Kahula
Ikaika

ʻO kekahi o nā hōʻailona nui loa o ka nele o ka enzyme ʻo ia ka hoʻololi o ka pahu. ʻO nā kīʻaha momona me nā mea ʻino maikaʻi loa a ʻaʻole hoʻi i hoʻonā ʻia ke ʻano o kēia maʻi.