ʻO Mikardis me nā kauoha no ka hoʻohana ʻana i ka lāʻau lapaʻau

ʻO ka wehewehe e pili ana i 24.08.2014

• Palapala Latin: Nā Micardisplus
• ʻĀkau ATX: C09DA07
• Mea waiwai: Kahikahana + Telmisartan (Hydrochlorothiaz>

ʻO ka papa ʻai Micardis Plus e loaʻa ai i 40 a 80 mg paha telmisartan a he 12,5 mg huinahui.

Nā mea hoʻoweliweli: sodium hydroxide, meglumine, povidone, sorbitol, magnesium stearate, lactose monohydrate, hao oxide ʻulaʻula mikuloculli selulose, sodium carboxymethyl starch,ʻano keʻa mahina.

Pharmacodynamics a me ka pharmacokinetics

Lapaʻau lāʻau

ʻO Mikardis Plus kahi hui telmisartan (ʻāpana pahu hoʻopiha ʻano ʻelua) a huinahui (diuretic ʻano thiazide). ʻO ka hoʻohana pū ʻana o kēia mau mea i ʻoi aku ka ikaika hopena antihypertensivema mua o ka hoʻohana ʻana iā lākou hoʻokahi. ʻO ka lawe ʻana i ka lāʻau lapaʻau 1 manawa i kēlā me kēia lā e alakaʻi i kahi hoʻohemo nui ʻana i ke kahe.

Telmisartan - nā mea koho pani koho hoʻopihaʻano lua. Loaʻa i kahi pilina koʻikoʻi no nā mea nānā angiotensin II AT1 subtype. ^ E Ha yM. Ua puka ʻo ia angiotensin II mai ka mea i koho ʻia. ʻO ka wā paʻa. Telmisartan ʻaʻole ia e pāpā i nā mea ʻē aʻe (me ke ʻano ʻAno AT2hoʻokipa) hoʻopiha. Telmisartanhōʻemi hoʻi i ka synthesis aldosterone.

I nā poʻe me haehae maʻi 80 mg telmisartan i kēlā me kēia lā ke hoʻopau loa i nā hopena hoʻopihaII. ^ E Ha yM. ʻO ka hoʻomaka ʻana o ka hana e loaʻa i ʻekolu mau hola ma hope o ke kau ʻana i ka lāʻau. Hoʻomau ka hana no kahi lā. Wahine hopena antihypertensive paʻa i hoʻokahi mahina ma hope o ka hana maʻamau telmisartan.

ʻO ka hole waiwai he diuretic thiazide ʻano. Hoʻopilikia ia i ka hoʻihoʻi ʻana o nā electrolytes i loko o nā ʻōpala o nā keiki, hoʻonui i ka hoʻonui ʻana o ka sodium a me nā chlorides. Hoʻopilikia kēia i nā kahe o ka neʻe i ka nui o ke koko, ka hana i hoʻonui ʻia reninhoʻonui i nā synt synt aldosterone.

Ma hope o ka noi huinahui ala ʻo diuresis ma hope o ʻelua mau hola, a hiki i ka hopena nui loa ma hope o ʻehā mau hola a lōʻihi no ka mau hola 6-12.

Lapaʻau lāʻau

Telmisartan.Hoʻopili koke ʻia mai ka lolo. Ka mākaʻikaʻi kiʻekiʻe telmisartanhele mai iloko o ka hola. ʻO Bioavailability 50%.

Nā pane me nā protein koko - ʻoi aku ma mua o 99.5%. Hoʻopili ʻia e ka pilina me waikawa glucuronic. ^ E Ha yM. Nā hua palapala telmisartan kūleʻa lāʻau paʻa ʻole.

ʻO ka hapalua hapalua he 20 mau hola. Hoʻokuʻu ʻia ia me nā feces i kāna ʻano kumu a me nā kinipoki - a hiki i 2%.

Lapaʻau lāʻau telmisartani nā elemakule, ʻaʻole ia i ʻokoʻa i nā maʻi o nā wā ʻōpio. ʻAʻole pono ke koho koho.

ʻO ka hole waiwai. Ma hope o ka lawelawe waha huinahui Loaʻa ka ʻike ʻana ma kahi o 1-2 mau hola. Loaʻa ka bioavailability 60%.

Hōʻike me nā protein plasma - 64%. ʻAʻole ia i hoʻohuli ʻia a hoʻopiʻi ʻia ma o nā keiki i loli ʻole.

Lapaʻau lāʻau

Telmisartan

ʻOiai e lawe nei i ka lāʻau lapaʻau i loko, ua hoʻihoʻi ʻia mai ka gastrointestinal tract i loko o ke koko no kahi manawa pōkole. Pono e hoʻokaʻawale kūpono i waena o nā lāʻau lapaʻau a me ka meaʻai. Inā hui pū kēia mau hana ʻelua, pono ua nalowale ke ʻano o ka lāʻau lapaʻau, e hoʻemi ana ka maikaʻi ma o ka hapalua pakeneka. E hōʻea ka ʻike hoihoi i ka pae i koi ʻia ma ʻekolu mau hola ma hope o ka inu ʻana o ka papaʻaina.

Ma hope o kekahi manawa, ʻo ka lāʻau i hoikeia i hoʻopuka ʻia ʻana ma o ka ʻōpū

ʻAʻole hana ʻia ka hoʻoponopono ʻia ʻana ma ke ʻano o ka makahiki o ka mea maʻi. Ma ke kino o ke kāne a me nā wahine i nā haʻawina, ua ʻike ʻia kahi ʻano like ʻole o ka waiwai, i kēia mea e hilinaʻi nei i ka hoʻomanawanui o nā ʻāpana a me ka wikiwiki o ka lilo ʻana.

I nā mea maʻi me ka hana renal impaired, ʻoi aku ka mea e hoʻopua iki ʻia ma mua o nā mea ʻē aʻe. Akā ʻokoʻa nō paha kahi ʻokoʻa o ka ʻenehana therapeutic i loko o nā kāne a me nā wahine.

Kohuia ʻO ka lāʻau lapaʻau ʻo Mikardis ka mea maʻamau i ka ʻike ʻana i nā maʻi like me:

• He maʻi hypertension,
• ʻO nā haunaele o ka puʻuwai aloha
• I mea e hōʻemi ai i ka maʻi cardiovascular a me ka make ma nā poʻe maʻi i hala i ka paepae kanaono mau makahiki.

Nā Hoʻohui

ʻO ka lāʻau Mikardis mai koho no ka malama ana i na hihia penei:

• Inā ua hōʻike ka mea maʻi i ka lolo ʻole i ʻole i nā mea nui a i ʻole nā ​​mea kōkua o ka lāʻau,
• ʻO ka hāpai ʻana a me ka lactation i nā wahine,
• ʻO nā mea maʻi ma lalo o nā makahiki he ʻumikumamāwalu
• Inā ua loaʻa kahi pilikia o brective bronchitis a i ʻole nā ​​maʻi like ʻole.
• Me ka hana pūlima āpau,
• Inā ua ʻike ʻia ka intolerance fructose,
• Me ka maʻamau aldosteronism.

Me ka mālama aka, hoʻohana ʻia ʻo Mikardis no ka nā lawehala:

• Hālina ka naʻau
• ʻO ka stenosis hāmeʻa renalela,
• High potassium
• Hema i ka hema
• Hoʻopau ʻole nā ​​puʻuwai naʻau
• A he mau pilikia ʻē aʻe o nā hana kino.

Ke ʻano o ka noi

Lawe ʻia nā papa Mikardis. ʻO ka ala kūpono o ka lāʻau lapaʻau hoʻokahi papa papa, me ka ʻai o 40 mg hoʻokahi i ka lā. Inā lawa ʻole kēia, hiki i ka nui o ka lāʻau lapaʻau ke pāpālua, akā, ʻaʻole nui. Hoʻohui mai ka lapaʻau, ʻaʻole hiki ke hoʻokō koke ʻia, no laila mai wikiwiki ʻoe e hoʻonui i ka pākē. ʻO ka mea mua pono e kali i ke ana o ka manawa mālama, ʻo ia mai ʻehā a ʻewalu mau pule.

ʻO nā mea maʻi e hoʻomau mau nei i nā kaʻina hemodialysis, ʻaʻole pono e ʻoi aku ma mua o ke ʻano i koho ʻia e ke kauka ma lalo o kekahi mau kūlana.

I nā maʻi me nā maʻi hōʻemi a me nā maʻi maʻalahi, ʻaʻole iʻoi aku ka nui o kēlā me kēia lā ma mua o 40 mg o ka lā.

No nā poʻe kahiko, liʻiliʻi ka nui o ka lāʻau lapaʻau no ka mea ʻaʻole e hōʻino.

E hoʻokuʻu i ke ʻano a me ka ʻano

Hana ʻia ʻo Mikardis Plus ma ke ʻano o nā papa - biconvex, oval, ʻelua-ʻāpana.

• dosage 40 / 12.5 mg a me 80 / 12.5 mg - hoʻokahi ʻāpana o ka pink-beige color, ka lua - ke keʻokeʻo keʻokeʻo me ka waihoʻoluʻu pink-beige interspersed, ma ka papa keokeo ka manaʻo o "H4" (40 / 12.5 mg) a i ʻole "H8" (80 / 12.5 mg), a me ka hōʻailona o ka hui (7 pcs. i loko o kahi kālaila, i loko o kahi pūpū pepa o 2, 4 a i ʻole 8 mau blisters),
• ke kīpē 80/25 mg - ke keʻokeʻo kahi papa, me nā waihoʻoluʻu o ka melemele, ʻōmaʻomaʻo ka lua, ma kahi papa keokeo aia kahi "H9" paʻi a me kahi pālahana huina (7 kēlā me kēia mea i loko o kahi pā koki, ma kahi pūpū pepa o 1, 2 a i 4 paha blisters).

Pākaukau 1 papa:

• mau mea ikaika: telmisartan - 40/80 mg + hydrochlorothiazide - 12,5 mg a i telmisartan - 80 mg + hydrochlorothiazide - 25 mg,
• Nā kumuhana hou: povidone, sodium hydroxide, meglumine, magnesium stearate, sorbitol, microcrystalline cellulose, lactose monohydrate, mais starch, sodium carboxymethyl starch, iron oxide red (40 / 12.5 a 80 / 12.5), iron oxide yellow ( 80/25).

Telmisartan

ʻO Telmisartan kahi antagonist kikoʻī (blocker) o nā ʻae A-II (AT₁ subtype) hōʻike i ka hopena antihypertensive me ka hoʻohana waha. Aia i kahi pilina kiʻekiʻe no ka AT₁ he subtype o na mea hoʻokae A-II, e hana ana i ka hana o kēia hope. ʻAʻole ia e hoʻonāukiuki i kekahi hopena agonistic ma luna o ke kaomi, mai kahi A-II i pio. ʻO ka mea hana a lohi loa i hoʻopaʻa pū ʻia i AT₁ he subtype o nā mea hoʻokae A-II, ʻoiai ʻaʻole ia e pili i kahi mea pili i ka AT₂ subtype, a me nā ʻenehana ʻē aʻe o ka angiotensin. ʻO ka hana nui o kēia mau mea nānā a me ka hopena o kā lākou hiki ke hoʻonui ʻia keu ma muli o ka mana o A-II, ʻo ka nui o ka piʻi me ka telmisartan, ʻaʻole i aʻo ʻia. ʻO ka mea hana i kumu no ka emi ʻana o ka paʻa o ka ald testosterone i loko o ke koko, ʻaʻole paʻa i ka neʻe ʻana o nā kahawai a ʻaʻole paʻa i ka pae o renin i ka plasma koko. ʻAʻole hoʻi ʻo Telmisartan i kāohi i ka angiotensin e hoʻohuli ana i ka enzyme (ACE) - kininase II, ka mea e hoʻopau ai i ka bradykinin, no laila, he nui ka piʻi ʻana o nā hopena makemake ʻole e like me ka bradykinin ʻaʻole i manaʻo ʻia.

I ka mua o ka hypertension arterial, ka hoʻohana ʻana o ka telmisartan i loko o kahi lāʻau o 80 mg e pale piha i ka hopena hypertensive o ka A-II. ʻO ka hana antihypertensive o ka waiwai ma hope o kāna hoʻoponopono waha mua i hōʻike ʻia i loko o 3 mau hola. Pono ka hopena o ka lāʻau lapaʻau no 24 mau hola a kū mau i nā hola 48. Hiki i ka hiki ke hoʻokō i kahi hopena hypotensive i 28 mau lā ma hope o ka hoʻomaka ʻana o ke papa, hāʻawi ʻia e lawe maʻamau ʻo Mikardis Plus.

I nā mea maʻi me ka hypertension arterial, hoʻoneʻe ka telmisartan i nā kaila koko systolic a me ka diastolic me ke ʻano ʻole o ka loli ʻana o ka puʻuwai puʻuwai (HR). Inā pono e hoʻopau koke i ka waiwai, e hoʻi mālie ke kahe koko i kāna mau kumu mua me ka loaʻa ʻole o ka pale o ka maʻi kāpae.

Ma nā haʻawina o ka telmisartan, ua loiloi nā hihia o ka maʻi cardiovascular, non-fatal stroke, non-fatal myocardial infarction, a i ʻole ka hoʻokipa ma muli o ke ʻano o ka puʻuwai puʻuwai (CHF). ʻO nā mea maʻi i ʻoi aku ma mua o 55 mau makahiki me ka hōʻeha, ka maʻi ʻalani coronary, maʻi maʻi artery peripheral a i ʻole diabetes mellitus me ka hoʻopukapuka ʻana i nā hanana kikoo (waiho i ka ventricular hypertrophy, retinopathy, he mōʻaukala o ka macro-a i ka microalbuminuria) i hōʻike i ka emi ʻana o ka morbidity cardiovascular a me ka make.

ʻO ka hole waiwai

ʻO ka Hydrochlorothiazide kahi diuretic thiazide. ʻO ka mea, e like me nā poʻe ʻelele o kēia papa o nā mea antihypertensive, e pili ana i ka kahe o ka reabsorption o nā electrolytes i loko o nā molula renal, hoʻonui hoʻonui i ka sodium a me ka klorida (ma kahi, i nā nui like). ʻO ka hopena o ka hana diuretic o ka lāʻau he hōʻemi i ka nui o ke koko kahe (BCC), he hoʻonui i ke kiʻekiʻe o ka plasma o renin i loko o ke koko, he hoʻonui nui aʻe o ka aldoster a me kahi hoʻonui hou aʻe i loko o ka waihona o ka pāhana a me ke bicarbonates i loko o ka urine, e alakaʻi ana i ka hoʻoemi ʻana o ka paʻū o ka pāhana i loko o ka plasma koko.

Me ka hoʻohana pū ʻana o ka waiwai me ka telmisartan, hiki ma muli o ka blockade o ka renin-angiotensin-aldosterone system (RAAS), ua hoʻemi ʻia ka poho potasi e pili ana i kēia diuretic. Ma hope o ka hoʻoponopono waha waha ʻana o ka hydrochlorothiazide, ua ʻike ʻia ka diuresis i hala ma hope o 2 mau hola, a ʻo ka hopena kiʻekiʻe ma hope o 4 hola. Hoʻololi ka hana diuretic o Mikardis Plus no nā hola 6-12.

ʻO ka lōʻihi o ka hoʻohana ʻana i ka hydrochlorothiazide e hōʻemi i ka hopena o ka hoʻopiʻi o nā maʻi cardiovascular a me ka make ma waena o lākou.

ʻO ka hopena antihypertensive o Mikardis Plus, ma ke ʻano he kānāwai, hiki i ka 4-8 mau pule ma hope o ka hoʻomaka ʻana o ka mālama ʻana.

Ke keu

ʻAʻole paʻa nā ʻōpana hemo o nā papa o Mikardis Plus.

Hiki i nā hōʻailona o kahi overdose o nā mea hoʻoikaika i ka lāʻau lapaʻau hiki i nā:

• telmisartan: bradycardia, tachycardia, hōʻailona hōʻailona i ka emi o ke koko,
• hydrochlorothiazide: hypokalemia, hypochloremia a me nā pilikia ʻē aʻe o ka hoʻāla wai wai-electrolyte, kahi hoʻemi ʻana i BCC, hōʻea i nā mea kuʻuna o nā muscuma a / a i ʻole nā ​​mea hoʻonāukiuki o nā māku cardiovascular (arrhythmias ma muli o ka hana like o ka glycosides cardiac a i ʻole kekahi mau lāʻau antiarrhythmic).

Me ka uluʻana o kēia mau hopena, ua hoʻākāka ʻia ke ʻano maʻi maʻi, ʻaʻole i hoʻoneʻe ʻia ka telmisartan mai ke koko me ka hoʻohana ʻana i ka hemodialysis. Hoʻohui ʻia ka Hydrochlorothiazide mai ke kino e ka hemodialysis, eia naʻe, ʻaʻole paʻa ka kiʻekiʻe o kona neʻe ʻana. Pono e nānā pono i nā pae o ka likaline a me ka hoʻoponoponoʻana i ka electrolyte i loko o ka serum o ke koko.

Nā ʻōlelo kikoʻī

I kekahi mau hihia, ma muli o ka pale ʻana i ka hana RAAS i ka wā o ka mālama ʻana i ka lāʻau, ʻo ka mea nui me ka mālama concomitant me nā lāʻau e pili ana i kēia ʻōnaehana, hana ʻino ʻia ka hana (me ka hoʻomohala ʻana o ka hana ʻoi aku ka maikaʻi ʻole). A ma muli ke ʻano, hoʻopiʻi ʻia e ka pālua me ka blockade pālua o RAAS (no ka laʻana, me ka hui ʻana o Mikardis Plus me ka ACE inhibitors a aliskiren) pono e hana pilikino ʻia, me ka mālama pono ʻana o ka hana renal (me ka nānā pono ʻana i ke kiʻekiʻe o ka pāhana a me ka hana i loko o ka serum koko).

I nā mea maʻi me ka maʻi puʻukui coronary (CHD) a me ka maʻi mellitus i ka wā e lawe ana i nā antagonist o nā receptors A-II, he nui ka loaʻa ʻana o ka maʻi myocardial fatal a me ka make lima o ka maʻi cardiovascular. No ka hele ʻana i ka maʻi mellitus o ka maʻi mellitus, hiki ke maʻi ʻia ka maʻi ʻeha ma muli o ke ʻano asymptomatic, no ka ʻike a me ka mālama ʻana ma mua o ka mālama ʻana, e koi ana ʻo Mikardis Plus i nā maʻi kūpono (me ka hōʻike ʻana me ka hana kino).

ʻO Hydrochlorothiazide kahi derphative sulfonamide a hiki i ke kumu o ka hoʻomohala ʻana o ka hopena idiosyncratic, i hōʻike ʻia i loko o ke ʻano o nā kokiʻoki ākeʻokiʻoki a me nā mīkē transient myopia. Nā hōʻailona o kēia mau hōʻiliʻili e hoʻopiʻi ai i ka hōʻeha o ka maka a i ʻole kahi hōʻemi i ke aniani ʻike, ʻo ia ka nui o nā hanana mai nā hola he mau mau minuke i hope o ka hoʻomaka ʻana o Mikardis Plus. I ka haʻalele ʻana o ka hana maʻi, ua hoʻomohala ʻia i ke kīpē aʻai ʻoi aku ka uhi ʻana o ka maka. No ka mālamaʻana i kēia hopena, ʻo ka mea mua loa, pono e kāpae i ka lawe ʻana i ka hydrochlorothiazide. Inā kū i ke kaomi intraocular ka hoʻomau i ʻole e hoʻomālamalama ʻia, mea e pono ai i ka ʻūlū aʻi ʻia paha e mālama. ʻO nā mea pilikia no ka pale ākea-kikina glaucoma i mōʻaukala kūlohelohe i ka penicillin a i sulfonamides.

ʻO ka Hydrochlorothiazide, e like me ka diuret thiazide ʻē aʻe, hiki ke alakaʻi i nā pilikia i ka hoʻāla wai-electrolyte a me ka kūlana o ka acid-base (hyponatremia, hypokalemia, a me hypochloremic alkalosis). ʻO nā ʻōuli o kēia hoʻopiʻi e komo paha i ka makewai, ka maloʻo maloʻo, nāwaliwali laulā, nā hopohopo, ke hiamoe nei i ka nāwaliwali o ka naʻau, nā myalgia a i ʻole ke hōʻule ʻana o nā ʻeha puʻupuʻu (crumpi), hōʻailona hōʻailona i ka hoʻokahe koko, nausea, luaʻi, tachycardia, oliguria.

Hoʻomaka ka hoʻoweliweli ʻana o ka hypokalemia i nā mea maʻi me ka cirrhosis o ka ate, i ke ʻano o ka hoʻonui ʻana o ka diuresis, me kahi papa paʻakai-paʻakai a i ka hopena o ka hui pū ʻana o Mikardis Plus me nā gluco- a me mineralocorticosteroids a i ʻole corticotropin.

ʻOiai ka mea ʻaʻole i hoʻopaʻa ʻia ka hyperkalemia koʻikoʻi i mālama ʻia i ka mālama ʻana iā Mikardis Plus, pono e hoʻomanaʻo ʻia i nā mea pili i ka hopena e pili ana i ka maʻi mellitus, ka naʻau a me / a me ka maikaʻi ʻole.

ʻAʻole ʻike ka ʻikepili e hōʻoia ana i ka hiki ke Mikardis Plus e hōʻemi a pale aku paha i ka hoʻomohala ʻana o ka hyponatremia e ka maʻi o ka diuretics ʻaʻole i loaʻa. Kūpono ʻia ʻo Hypochloremia, ma ke ʻano he kānāwai, he nui ʻole ka mea e pono ai ka mālama ʻana.

Hoʻonui ʻo Thiazide diuretics i ka hopena o ka hoʻemi ʻana i ka calcium excretion e nā keiki a me ke ʻano o kahi neʻe a me ka hoʻonui iki ʻana i nā pae calcium serum. ʻO ka hoʻomohala ʻana o ka hypercalcemia koʻikoʻi paha he hōʻailona ia o ka hyperparathyroidism latent. Inā makemake ʻia kahi loiloi o ka hana parathyroid, pono e hoʻoneʻe ʻia ka thiazide diuretics.

ʻAʻole emi ka hana a Mikardis Plus i nā mea maʻi ma ka lāhui Negroid.

Nā hopena hopena

• Mai ka papa hanu: pōkole o ka hanu, ʻeha hopohopo ʻeha.
• Mai ka pūnaehana neʻe: tachycardia, nā arrhythmias, brieociaia, kahi emi ikaika o ke kaomi.
• Mai ka ʻōnaehana pīpī: nāwaliwali, alohaāhāhuʻe ʻōpalahopohopo manaʻo ʻinohuhū, ʻeha.
• Mai ka pūnaehana hana ʻana: ʻōpūmaloʻo, ʻōpū ʻōpū, constipationgastritis, hypercholesterolemia, hyperglycemia, pancreatitis,jaundice ʻĀpepsia.
• Ma ka ʻāpana o ka ʻili.
• Mai ka ʻōnaehana musculoskeletal: nā māka wīwī, aolaila, myalgia, huhulapaiʻeha ka ʻeha.
• Mai ka ʻōnaehana hemopoietic: leukopenia, eosinophilia, anemia, neutropenia, thrombocytopenia, thrombocytopenia.
• Mai ka kiko genitourinary: pilikia ʻole, nephritis, glucosuria.
• Mai nā maka: ʻike maka, glaucoma, xanthopsia, ʻopa myopia.
• Nā maʻi: sepsisnā maʻi hanu (pharyngitis, bronchitis, sinusitis), nā uluʻana o nā kohu salivary.
• ʻO nā maʻi ma ka pālahalaha: hoʻonui creatinine, nā ate enzyme, creatine phosphokinase, uric acid i loko o ke koko hypertriglyceridemia, hyperkalemia, hypokalemia, hypoglycemia, hyponatremia, hoemi hemoglobin.
• Allergic hopena pili: ʻiliʻala, angioedemaʻohiʻala erythema, hopena anaphylactic, eczema, ʻōnaehana vasculitis, necrotic vasculitis.

Hoʻohui

Ke kaʻana telmisartan me ka:

• ʻO nā lāʻau lapaʻau antihypertensive ʻē aʻe - hiki ke hoʻonui aʻe i ka ikaika hopena antihypertensive,
• nā lāʻau lapaʻau lithium - hiki ke hoʻonui iki i kekahi manawa lithium i loko o ke koko
• nā mea kanu anti-inflammatory - hiki mau hiʻohiʻona huehae huehal i pau i ka poʻe maʻi me ka hoʻemi ʻia ʻana o ka nui o ke koko,
• kāmakua - hiki ke hoʻonui ma ke koʻikoʻi kāmakua i loko o ke koko e 20%.

Me ka hoʻohana ʻana huinahui me ka:

• barbiturates, ethanol a i ʻole opioid painkillers - hiki ke hoʻomohala ʻia orthostatic hypotension,
• Metformin - hiki hiki ke hoʻomohala lactic acidosis,
• nā mea lawelawe hypoglycemica insulin - pono ʻia ka hoʻoponopono ʻana nā lāʻau maʻi hypoglycemic,
• cholestyramine a colestipol- hiki ke pale ʻia ʻana o ka pā huinahui,
• hoʻomaha ʻole ma ka pale ʻana i ʻole e hoʻohemo ʻana - hiki ke hoʻonui i kā lākou hopena,
• cardiac glycosides - hiki hiki ke hoʻomohala hypokalemiaa i ʻole hypomagnesemia,
• anti-gout agents - hiki ke hoʻonui ʻia i nā ʻike waawa uric i loko o ke koko.
• hoʻomākaukau ʻana o ka calcium- hiki ke hoʻonui ma ka paʻa kalaiula i ke koko ma muli o ke kaohi ʻana o kona kāpae ʻia e nā keiki.
• amantadine- hiki ke hoʻonui ʻia i ka loaʻa ʻana o nā hopena i makemake ʻole ʻia amantadine,
• m-anticholinergic blockers(atropine, ʻaina kala) - hiki i ka nāwaliwali pono o ka huina o ka ʻōpū, hoʻonui bioavailability diuretics thiazide,
• nā mea kanu anti-inflammatory - hikiwaliwali paha diuretic a hopena antihypertensive.

1. Ke kuhikuhi no ke komo ʻana

Ma ka ʻatikala hiki iā ʻoe ke ʻike i nā ʻikepili i nā hōʻailona, ​​nā ʻano hoʻomalu a i ʻole ka hopena i koi ʻia (inā e koi ʻia, pehea e helu ʻia ai), ʻano, ʻano, i mea e hiki ai i kēia lāʻau lapaʻau ke hoʻohui, i hui pū me kēia lāʻau lapaʻau, nā ʻano kīnā ʻole i ʻae ʻole ʻia. lawe i ka lāʻau lapaʻau, waena o nā kumukūʻai, nā mea hoʻohālike, a me nā loiloi o nā maʻi e lawe ana i kēia lāʻau lapaʻau.

Eia kekahi, eia hoʻi hiki ke loaʻa nā ʻikepili i nā mea e hana inā loaʻa koke ʻoe i kahi overdose. Pono e ʻike pono kēia ʻike a pau e kū i nā hopena maikaʻi ʻole.

Nā hopena hopena

I ka wā o ka mālama ʻana me Mikardis, pēlā collateral nā hopena:

• Pūnaehana pīhoihoi waena - kaumaha, vertigo, hopohopo, insomnia, nāwaliwali,
• Hōʻeha - cystitis, pākuʻi ʻana i ke ake o ka ʻōpū o ka ʻōpū, sepsis,
• Pūnaehana pāʻālua - thrombocytopenia, anemia, hoʻemi i ka pae o ka hemoglobin level,
• Ka ʻike - ʻike maka ʻole ʻia nā kiʻi a i ʻole nā ​​pilikia ʻē aʻe.
• Pūnaehana digestive - kahe maloʻo, ʻeha o ka ʻōpū, ka luaʻi, ka lua
• ʻO nā ʻeha a me nā iwi - ʻeha hoʻi, myalgia, nā ʻeha ʻo nā ʻeha a me nā ʻōpū, nā kūlana paʻa ʻole.
• A ʻo nā hopena ʻē aʻe kekahi e kū mai paha, no ka laʻana, ka nāwaliwali laulā, ke hiamoe ʻana, ke ʻeha paha i kekahi mau wahi o ke kino.

Ka kuʻikahi me nā lāʻau lapaʻau ʻē aʻe

Hiki i ka mea ikaika o ka lāʻau ʻo Mikardis ke hoʻonui i ka hopena o nā lāʻau lapaʻau, e hoʻohuli i ke kahe o ke koko.

A me ka hoʻonui ʻana o ka digoxin i ke kino e hoʻonui, ma muli o kahi e pono e kiaʻi mau i nā hoʻokolohua.

me ka hoʻohana ʻana o ka lāʻau Mikardis i ka lāʻau, e loli paha ka hoʻololi ʻana wohalehu ka lāʻau lapaʻau, a hoʻololi i ka hana o ka hopena o ke ʻano kino i loko o ke kino.

Nā kūlana mālama

Pono e mālama ʻia ka lāʻau i waho o ka hiki o nā keiki. Hiki iā ʻoe ke loaʻa iā ia i loko o kahi lumi kahi e ʻaʻole eʻoi aku ai ka wela ma mua o ke kanakolu kiʻekiʻe. Nā papa hana, inā ʻaʻole i wāwahi ʻia, mālama ʻia kā lākou paena pilikino no ʻekolu mau makahiki, ma hope o ke hoʻohana ʻana aole i kauohaia.

ʻOiai ma ke kahua o ke koho ʻana i ka lāʻau lapaʻau, ua haʻi ʻia iaʻu i ke ʻano he therapeutic ikaika ʻo Mikardis. Ua hoʻoholo wau e hoʻāʻo iā ia iho, ʻoiai ʻoiai he nui ka mea hōʻike. Lawe i nā paila, he kauka i kau aku ai i nā hebedoma e hoʻonui i ka hopena. A ua hoʻomaka ka mālama ʻana. Heʻoiaʻiʻo nō ke kiʻekiʻe o ke kumukūʻai noʻu, akā ua hoʻoholo wau i ka like ʻana o nā analog e like me ka like ʻana o Mikardis iā ia iho a inu i ka kumu. I loko o hoʻokahi pule, ua ʻoi aku ka maikaʻi. Mahalo i nā kauka a me Mikardis.

I ka maʻi ʻana o koʻu makuahine, ua hoʻāʻo mākou i ka nui o nā lāʻau lapaʻau, e hoʻāʻo ana e hoʻopaʻa i kāna kūlana, akā ʻaʻole lākou i kōkua no ka lōʻihi. Ma hope o ka kamaʻilio ʻana me ke kauka ma ka haukapila, hoʻoholo mākou e hoʻāʻo e hōʻike i kahi hoʻohālike kumu kūʻai o Mikardis. ʻOiai hikiʻole ke hoʻomaka ke hana ikaika i ka lāʻau. Nui wau i ka ʻoiaʻiʻo ua ʻae ʻia ke kumukūʻai a me ka hoʻonohonoho ʻana o nā mea ikaika i kūpono i kā mākou mau hōʻailona. Mahalo i kēlā me kēia mea i paʻi ʻia i kā mākou koho i kēia lāʻau lapaʻau.

Ua kuhikuhi mai ke kauka iaʻu e lawe i ka lāʻau lapaʻau Mikardis hoʻohui. Ma hope o ka heluhelu ʻana i nā loiloi ʻē aʻe e pili ana i nā hopena ʻona ma ke kino, ua hoʻoholo wau e hoʻāʻo i nā analogues. Ua like lākou me ka hana ʻino ʻana mai i koʻu kino ʻūlū ʻia. Akā ma hope o kekahi manawa, liʻiliʻi ka hopena o ka therapeutic a ua hoʻoholo ʻia e hoʻohana mau i ka lāʻau medardis i kālai ʻia. Ua lilo i mau mea maikaʻi aku ʻoi loa.

Hoʻohui a me nā hopena lāʻau lapaʻau o ka lāʻau

ʻO ke kumu nui o ka lāʻau lapaʻau ka telmisartan. ʻO kahi papa papa o kēia māhele ua loaʻa nā 80, 40, a me 20 milligrams. ʻO nā mea hoihoi o ka lāʻau lapaʻau e hoʻomaikaʻi i ka hoʻopili ʻana o ka mea nui: meglumine, sodium hydroxide, polyvidone, sorbitol a me ka magnesium stearate. ʻO kēia lāʻau lapaʻau, ʻo ka hoʻohui ʻana i ka telmisartan, he 12,5 milligrams o hydrochlorothiazide - kahi waiwai e diuretic. ʻO ka hui pū ʻana o ka diuretics a me ka angiotensin antagonist e hiki ai i ka hopena hou aʻe i ka hopena hypotensive. Loaʻa ka hopena diuretic ma kahi o ʻelua mau hola ma hope o ka lawe i ka paila.

ʻO Mikardis Plus kahi antagonist o nā receptors no ka angiotensin hormone. Hoʻonui kēia hormon i ke kani o nā paia vascular, e alakaʻi ai i kahi hōʻemi i ka hoʻomaʻemaʻe ʻana o nā kīʻaha koko. Hoʻohālikelike ka Telmisartan i ka hana kemika i nā subspecies o nā ʻalemona angiotensin.

Ma hope o ke komo ʻana i ke kino, hoʻohālikelike kēia lāʻau lapaʻau i nā mea paʻa me nā mea hoʻomaʻamaʻa, e alakaʻi ana i ka neʻe o ka angiotensin, no laila e kāpae nei i ke kumu nui no ka hoʻonui ʻana i ke koko. Ke alakaʻi nei ʻo Telmisartan i kahi hoʻohaʻahaʻa i ka systolic a, ma kahi, ka hoʻonaninani diastolic, akā ʻaʻole kēia mea e hoʻololi i kona ikaika i kekahi ala me ka nui o nā kirimana o ka puʻuwai naʻau. He aha ka ʻōlelo a Mikardis Plus e haʻi iā mākou?

Ke hoʻohana mua nei i ka lāʻau lapaʻau i ka neʻe ʻana o ka huki mau o ke kaomi: e nee malie ana me ka lōʻihi o kekahi mau hola. Ka hopena Antihypertensive ma hope o ka lawe ʻana i nā papa i nānā ʻia ma kahi liʻiliʻi ma hoʻokahi lā. No laila, i mea e mālama ai i ka luhi i ka maʻamau a ma lalo o ka mālama, pono ia e inu i ka lāʻau lapaʻau i hoʻokahi manawa wale i ka lā. ʻO ka nui, a ma ka manawa like, hoʻomau mau ka hoʻoneʻe ʻana i ke kao ma loko o hoʻokahi mahina ma hope mai o ka hoʻomaka ʻana o ka hana me ka lāʻau lapaʻau i hōʻike ʻia. I nā hihia a hoʻokaʻawale koke ka lāʻau lapaʻau, ʻaʻole i ka hopena o ka haʻalele ʻana, ʻo ia hoʻi, ke hoʻi hou ka hopi i ka hōʻailona kumu ʻaʻole i hoʻohālike maoli, akā, ma ke ʻano he kānāwai, e hoʻomaʻamaʻa ʻia kēia i kekahi mau hebedoma.

Hoʻopili maikaʻi ʻia nā mea āpau o Mikardis Plus, ke lawe waha ʻia mai loko mai o ka ʻōpū, hiki i ka bioavailability o ka lāʻau ke aneane he kanalima hapalua. Hoʻoholo ʻia ka ʻike kiʻekiʻe loa o ka hana ikaika i ka plasma ma hope o ʻekolu mau hola. ʻO ka kaʻina hana hoʻouluulu e kū nei ma o ka hopena o ka telmisartan me ka waikawa glucuronic. ʻO ka huakaʻi neʻe i ka hana ʻole. ʻO ka hapalua o ke ola o ka lāʻau mālama ma mua o ka iwakālua mau hola. Hoʻopili ʻia ka lāʻau lapaʻau i ka laikini. ʻO ka urine, ʻaʻole i emi iho ma hope o ʻelua mau pakeneka o ka lāleka me waho.

Loaʻa nā papa nā Mikardis Plus i nā ʻekolu ʻekolu: 80, 40 a 20 milligrams o telmisartan. Eia ka nui o nā mea hoʻihoʻi ikaika, nā papa āpau i kahi ʻano elongated a me ka waihoʻoluʻu keʻokeʻo. ʻO ke kahakaha ʻana o ka ʻoihana ua paʻi ʻia ma kekahi ʻaoʻao o ka papa. 40 mauʻu milligram i loaʻa hoʻi i ka 51N. ʻO kēlā mau 80 milligrams i kālai ʻia me kēlā me ka waiwai 52N. Ma ka ʻatikala hoʻokahi mai ʻelua a ʻewalu polū, kēlā me kēia papa he ʻehiku mau papa.

I ka manawa hea e hoʻohana ai i ka lāʻau lapaʻau?

Wahi a nā ʻōlelo kuhikuhi, ua kūkulu ʻia ʻo Mikardis Plus (80 + 12, 5 mg) no ka mālama ʻana i ka maʻi hypertension. Ua kau kekahi mau kauka lāʻau i kēia lāʻau lapaʻau no nā poʻe maʻi ma mua o kanalima kumamalima mau makahiki i ʻike ʻia he nui ka piʻi ʻana o nā pilikia cardiological koʻikoʻi e pili ana me ka hypertension arterial. He mea kūpono ʻole e kuhikuhi ʻia ka lāʻau ma ka hihia inā ʻaʻole hiki ke hoʻokō i ka hoʻemi koi ʻana o ka ʻai ma ke ʻano o ka lawe ʻana i kēia ʻano maʻamau.

ʻAʻole ia e kuhikuhi i kēia lāʻau lapaʻau iā ʻoe iho a koho i kāna kūmole, ʻoiai he mea kauka wale nō ke ʻike i kekahi mau contraindications ma ka loiloi pololei ʻana i nā loiloi a ka mea maʻi. Hiki nō ke ʻōhua i nā hopena ʻaoʻao i ka pololei pololei i koho ʻia ai ka noho lāʻau lapaʻau.

I ka manawa e manaʻo ʻia ai ka lāʻau lapaʻau contraindicated?

ʻAʻole pono ka hoʻokō ʻia me ka lāʻau lapaʻau i nā pilikia aʻe:

• I nā kūlana kahi i loaʻa ka hypersensitivity i nā mea nui a me nā mea waiwai hou o kēia huahana lapaʻau.
• ʻAʻole kūpono kēia lāʻau lapaʻau i nā wahine e kū nei, akā, ʻoi aʻe, inā e lawe ʻia ka ʻōpala.
• ʻAʻole kūpono ka lāʻau lapaʻau inā hiki i nā mea maʻi ke loaʻa nā pathological tract path e pili ana i kā lākou patency ākea.
• I ka loaʻaʻana o nā hana ʻino koʻikoʻi i ka hana o nā pūpū a me nā ate.
• I nā kūlana i hoʻoili ʻia he intolerance fructose.

Pono e koho ʻia nā ʻōlapa ma ka mālama ʻana i ka maʻi hypertension i nā keiki a i ʻole nā ​​ʻōpio. ʻO kēia ke kumu o ka hōʻoiaʻana o ka telmisartan i kahi mea i loʻi ʻia ʻaʻole i hoʻokō piha. Hōʻike nā ʻōlelo no ka hoʻohana ʻana me Mikardis Plus e hoʻohui ʻia i nā contraindications ma luna aʻe, ʻaʻole hiki ke kuhikuhi ʻia i nā mea maʻi e maʻi ana i ka hypercalcemia refractory, a he mea ʻole hoʻi no ka hypokalemia, ka hemahema ma muli o ka intolerance i ka galactose me ka lactose.

Hāʻawi ʻia nā contraindications relative i ka lāʻau Mikardis Plus (80 mg). No ka laʻana, pono e mālama pono nā kauka a kuhikuhi i kahi hoʻohaʻahaʻa haʻahaʻa loa i nā hanana ma ka mōʻaukala o nā mea maʻi hypertensive aia nā ala āpau:

• ʻO ka hoʻomohala ʻana o ka hyponatremia a i ʻole hyperkalemia.
• ʻO ka heleʻana o ka ischemia cardiac i nā maʻi.
• ʻO ka hoʻomohala ʻana i nā maʻi naʻau like ʻole, no ka laʻana, i ka ʻano o ka paʻa o ka maʻi, ka stenosis valve a me ka cardiomyopathy.
• ʻO ka hiʻohiʻona o ka stenosis o nā palaki o nā keiki. I nā kūlana kahi i loaʻa ai i ka mea hoʻokahi wale nō ka maʻi, pono e mālama ʻia ka mālama kūikawā i ka wā o ka hoʻokele ʻana i ka lāʻau lapaʻau i ka wā e loaʻa ai ka stenosis o ke aʻa wale ka hana e hoʻokō i nā hana o ke koko.
• ʻO ka hoʻomohala ʻana o ka hoʻomāhu ʻia, ka mea e hoʻopiʻi ʻia e nā maʻi me ka hoʻopiʻi a i ʻole nā ​​palapala ʻeha.
• ʻO ka maʻi diuretic o mua.
• Hoʻouka i ka poʻe maʻi ma hope o ka hoʻololi ʻana i kahi keiki maʻi.

Hoʻopili i nā maʻi i luna aʻe, me ke koho ʻana iā Mikardis Plus, pono e mālama pono kekahi i nā mea maʻi e loaʻa ka maʻi a me ka gout.

Loaʻa paha nā hopena ʻaoʻao i ka wā o ka hoʻokele

ʻAʻole ʻike ʻia nā loiloi e pili ana i "Mikardis Plus" e kahi loiloi maikaʻi. Hoʻomaopopo kekahi mau maʻi i ka hakahaka o nā loli like ʻole i ko lākou mālama pono ʻia. Pono e hoʻolōʻihi ʻia ka hoʻomohala koke ʻana i ka hopena o nā mea pono ʻole, ma ka hopena o ka lāʻau lapaʻau, a, aia hoʻi, i ka wā o ka maʻi o ka mea maʻi a me ka hele ʻana o nā hanana concomitant. No laila, hiki pinepine pinepine ke nānā i kēia mau loli i ka wā e lawe nei i kēia lāʻau lapaʻau.

• ʻO ka helehelena o ka hakahaka o ka manawa, loko o ke poʻo, ka ʻeha a me ka hopohopo a me ke kaumaha e hopohopo nei, ʻehaʻeha, a, ma nā kūlana he nui, ʻaʻole i hoʻoneʻe ʻia nā hoʻohewa.
• ʻO ka hoʻonui nui ʻana i ka hiki mai o ka ʻōpū o ka hanu i nā pathogens infectious, kahi e lilo ai i kumu nui o ka pharyngitis, sinusitis, bronchitis, paroxysmal kaʻo a me nā mea like.
• ʻO ke ʻano o nā maʻi dyspeptic i ke ʻano o ka nausea, colic, a, ʻo ka mea hoʻi, nā maʻi o ka maʻi. I kekahi o nā maʻi, hiki i nā hoʻokolohua ke hōʻike i ka nui o ka enzyme hepatic.
• Ke ʻano o ka hypotension - kiʻi i ka ʻōpū o ka umauma. Eia nō hoʻi, ʻo ka hoʻomohala ʻana o ka tachycardia a i ʻole, ʻaʻole i haʻalele ʻia ka bradycardia.
• ʻO ka uluʻana o ka eha o ka pena a me ka arthralgia. ʻO ka hiʻohiʻona o ka ʻeha ma ka lumbar.
• ʻO ka hoʻomohala ʻana o nā ʻaina hopuna o ka pā genitourinary a me ke mālama ʻana i nā wai o ke kino.
• ʻO ka hopena o nā hopena alia i ke ʻano o ka rashes o ka ʻili, urticaria, me ka angioedema, heching a he erythema paha.
• Ma kahi ʻāpana o nā hoʻokolohua hoʻopaʻa ʻana, hiki ke ʻike ʻia ka hyperkalemia me nā hōʻailona o ka anemia.

I loko o ka hoʻolālā o nā noi preclinical o ka lāʻau "Mikardis Plus," ua hoʻokū ʻia ka hopena fetotoxic o ka lāʻau. Hāʻawi ʻia i kēia ʻano, he mea pono ʻole ke lawe i kēia lāʻau lapaʻau i ka wā hānai. I ka hanana ʻana ka manaʻo, a laila ʻo ka wahine, e like me ke kauoha a ke kauka, pono e hoʻololi i nā lāʻau antihypertensive ʻehaʻeha. I nā hihia kipi, ua hoʻopau koke ka hoʻohana ʻana o kēia lāʻau lapaʻau.

Nā hiʻohiʻona o ka hoʻohana

ʻO ka lāʻau lapaʻau ʻo "Mikardis Plus" pono i kuhikuhi ʻia e ke kauka. Hiki ke hoʻohana kū hoʻokahi a i ʻole me nā hoʻomākaukau lāʻau lapaʻau ʻē aʻe, ka hopena o ka mea e manaʻo ai e hoʻonui pono i ka hana o ka ʻōnaehana cardiovascular. Ua hōʻike ka mea lapaʻau i ka hana o kēlā me kēia lā o Mikardis Plus e kaupalena ʻia i hoʻokahi papa me ka nui o ka 40 milligrams o ka hana ikaika.Akā i ka manawa like, he mea nui e noʻonoʻo ʻo ia i nā mea maʻi e loaʻa mai nei i kahi ʻano maʻi hypertension ka hopena, hiki i ka hopena hypotensive hoʻomau i kekahi manawa i ka wā e lawe ana i ka nui ka iwakāluakūmālua o milligram.

Ke lawe ʻia nei ke koho ʻana o kahi maʻi therapeutic no nā liʻiliʻi ʻehā pule. Pono ka manawa pono no kēia lāʻau lapaʻau e hōʻike i kona hopena therapeutic piha. Inā loaʻa ʻole ka hopena i makemake ʻia i kēia manawa, ua ʻōlelo ka hoʻomanawanui e lawe iā Mikardis Plus ma kahi kikowaena o 80 milligrams. I mua o nā hoʻopiʻi keu e pili ana i ka maʻi hypertension, ʻae ʻia ka lawelawe o ka lāʻau lapaʻau ma ka nui o 160 milligrams o ka telmisartan, ʻo ia hoʻi, e koi ʻia nā papa ʻelua o 80 milligrams. Pono e haʻi ʻia ma muli o ka diuretic o kahi ʻāpana o Mikardis Plus (80 + 12, 5 mg), ke emi ka nui o ka maʻi i nā mea maʻi ma mua o ka lawe ʻana i ka mana maʻamau o kēia lāʻau lapaʻau.

Pēlā, e koho ke kauka i ke ʻano o ka lāʻau lapaʻau i hoʻohui ʻia e pili ana i ka nui o ka papa o ka hypertension. Hōʻike pinepine nā loiloi e pili ana i "Mikardis Plus" i ka hopena hypotensive i haʻi ʻia. ʻO ka lāʻau lapaʻau i hōʻike ʻia i nā manawa a pau o ke ao. I ka manawa like, ʻaʻole ʻai ka ʻai i ka hoʻāʻo ʻana o nā mea o ka lāʻau. Kuhi ʻia ka nui o ka komo ʻana e ke kauka, ma muli o ke ʻano o ka mea maʻi, hiki i ke kauka ke ʻōlelo aku i ka huli ʻana i kahi papa mālama mālama o 20 milligrams.

ʻO nā mea maʻi e loaʻa ana i ka mōʻaukala o ka hōʻino ʻana o ka pilikia, ʻaʻole ia e hāʻawi ʻia i hoʻokahi kū hoʻokahi. I ka hanana nā loli pathological loli i nā hana ate i loko o ka anamnesis, pono wale nō ke koi ʻia o "40". Pono e hoʻomaopopo ʻia he piʻi nui kekahi o ka wai i ka pau ʻana o ka hana o ke kino. Pēlā no nā maʻi maʻi maʻi, ʻaʻole pono lākou e hoʻoponopono i ka paukō.

ʻO ka hopena o ka hana ikaika o ka lāʻau lapaʻau ma ka hiki ke ohe i nā maʻi e hoʻokō i nā mīkini

ʻO nā ʻōlelo i hoʻopili ʻia no ka hoʻohana ʻana i ka lāʻau "Mikardis Plus" (40 a me 80 milligrams) hōʻike i ka ʻike ʻole ʻana i hoʻokolohua kūikawā i pili i ka hopena o ka lāʻau lapaʻau ma ka neʻe o ka nānā, a me ka wikiwiki o ka hopena. Eia naʻe naʻe, ʻoiai e lawe ana i nā lāʻau lapaʻau me ka hopena hypotensive o ka pākuʻi ʻana, pono e hoʻomanaʻo ka mea i ka hoʻomākaukau ʻana o ka lāʻau lapaʻau me kēia ʻano. Ma ka hanana ʻo nā limahana e pili pū ana me ka mīkini lawelawe he mau like like, a laila e hāʻawi ʻia lākou i nā kikowaena o Mikardis Plus (80 a 40 mg).

Nā hiʻohiʻona o ka mālama i ka lāʻau a me nā uku

Pono e mālama i ka lāʻau lapaʻau i kahi e hoʻokaʻawale ʻia ai ka hiki ʻana i nā keiki. ʻAʻole pono ʻo ka mahana o ka lumi mālama mālama i nā kanakolu kiʻekiʻe. Ma ke ʻano he kānāwai, hiki ke mālama ʻia nā papa me ka nui o ka 40 a me 80 milligrams me ka ʻole e hōʻino i ka kūlike o ka moʻo ʻana no nā makahiki ʻehā mau makahiki mai ka manawa i hana ʻia ai lākou. Loaʻa i nā papa 20 milligram i kahi ola pōkole ʻoi aku ka lōʻihi o nā makahiki ʻekolu. ʻO ke kumukūʻai o ka lāʻau lapaʻau "Mikardis Plus" i kahi lāʻau lapaʻau i hilinaʻi pololei ʻia i ka hopena o ka lāʻau ikaika i ka lāʻau lapaʻau.

• Oe ke kuai i ka lāʻau lapaʻau no 40 milligrams, ma loko aʻe o nā papa he ʻumikumamāhā, no elima mau rubles.
• ʻO Mikardis Plus 80 milligrams me nā papa he iwakāluakumamāwalu i loko o kahi lāʻau lapaʻau he kumukūʻai he ʻeiwa a me kanalima mau rubles.
• ʻO ke kumukūʻai o ka hopena hoʻomaha no nā papa he iwakāluakūwalu mai ka ʻewalu haneri a me kanalima rubles.

ʻOiaʻiʻo, ʻaʻole kēia o kēia ʻike i ka ʻōlelo kuhikuhi no ka hoʻohana ʻana me Mikardis Plus.

Nā hiʻohiʻona o ka lāʻau

He kūpono loa nā loiloi e pili ana i ka lāʻau lapaʻau, ʻoiai he mea maʻamau ka poʻe i hoʻohana i kēia lāʻau lapaʻau i ka hōʻemi pinepine ʻana i nā hopena ʻaoʻao a hōʻike hoʻi e maikaʻi ana kēia lāʻau lapaʻau, a ʻo ka mea nui hoʻi, ka hoʻohaʻahaʻa koke i ke kaumaha. ʻOiaʻiʻo, nā mea mai ke kūʻai ʻana o kēia pono hana e hooki ʻia e kona kumukūʻai kiʻekiʻe. E pono e kamaʻāina iā ia iho e koho i ke kauka i nā mea hou aku i nā lāʻau lapaʻau ʻo Mikardis Plus. No laila, ʻo nā lāʻau lapaʻau e pili ana i ka lāʻau kaulana loa me ka hopena a me ka hopena i ke kino: "Telmisartan", "Teveten", "Teseo", "Hypotel" a me "Pritor".

ʻO ke kumukūʻai o nā kīʻaha o "Mikardis Plus" pili pono i kā lākou mea hana, a, ʻo ia hoʻi, ma ka ʻano o nā papa. Ma ke kumukūʻai liʻiliʻi a emi aʻe paha, hiki iā ʻoe ke kūʻai, no ka laʻana, e like me nā lāʻau like e like me Angiakand, Valz a me Blocktran. Pono e aʻo ʻia nā ʻōkuhi no ka hoʻohana ʻana i nā analogue, no ka mea e hiki ai ke ʻike i nā contraindications āpau me nā nuances o ka hoʻohana.

ʻŌpū a me ka lactation

Hoʻohana nā wahine hāpai i ka Mikardis Plus. ʻAʻole kuhi ʻia ka loaʻa ʻana o nā antagonist o nā taliaina A-II i ka trimester mua o ka hāpai ʻana. I ka hihia o ka hōʻoia ʻana i ka hapai, pono e hoʻokuʻu koke ʻia ka hoʻohana ʻana o kēia mau lāʻau. Inā pono, e kuhikuhi ʻia nā mea maʻi hou i nā lāʻau antihypertensive hou i loaʻa ka paʻa palekana palekana i ka wā hāpai.

I loko o ka II - III trimesters, therapy me A-II receptor blockers contraindicated, no ka mea, i ka wā preclinical Studies ua ʻike ʻia i loko o kēia mau wā o ka hapai hiki iā lākou ke hōʻeha i ka fetotoxicity i loko o kahi kanaka (lohi ossification o ka ʻōpala, oligohydramnion, hana hana ʻole ʻia), a me ka huʻi neonatal (hyperkalemia, hypotension, renal failed). Inā mālama ʻia ka hoʻomaʻamaʻa ʻana me nā antagonist o nā receptors A-II i ka lua o ka hapalua o ka hapai ʻana, e nānā ʻia kahi scan ultrasound o nā iwi o ka ʻiwi a me ka hana ʻana i ka pūpū. ʻO nā pēpē i hāpai i kā lākou mau makuahine i nā lāʻau lapaʻau o kēia papa e nānā pono ʻia no ka hypotension arterial.

Hoʻohana ʻia ka ʻike no ka hoʻohana ʻana iā hydrochlorothiazide i nā wahine hāpai, ʻoiai hoʻi i ka trimester mua. Ua ʻike ʻia ka mea e hele a me ka waiwai o ka maʻi plasenta ka waiwai, a me ka noʻonoʻo ʻana i ka ʻano o ka lāʻau lapaʻau o kāna hana, hiki ke manaʻolana ia e lawe ʻo Mikardis Plus i ko II - III trimesters o ka hapai hiki ke hoʻonāukiuki i ka hana piha o ka fetoplacental a me ka hopena i nā hopena kūpono ʻole i ka embryo / fetus, e like me thrombocytopenia, jaundice, hemahema electrolyte. ʻAʻole pono e hoʻohana ʻia ʻo Hydrochlorothiazide no ka hypertension arterial a me ka edema ma muli o ka hānau ʻana, no preeclampsia (ma muli o ka ulu o ka hoʻohanohano o ka hoʻokaʻa ʻana o ka nui o ka plasma a me ka hoʻokaʻawale ʻana i ka puhala plasenta), a me ka lilo ʻole o ka hopena maikaʻi i loko o kēia mau maʻi.

No ka mālamaʻana i ka hypertension pono i loko o nā wahine hāpai, hiki ke kuhikuhi ʻia ka hydrochlorothiazide i nā hihia koʻikoʻi loa, i ka wā hiki ʻole ke hoʻohana i kekahi lāʻau ʻē aʻe.

Hoʻomoʻa a contendicated ʻo Mikardis Plus i ka wā o ka hoʻoulu ʻana.

ʻAʻole i hana ʻia nā noiʻi o ka hopena o ka lāʻau i ka hoʻomohala kanaka.

Hōʻike nā kauka i nā kauka

Wahi a nā poʻe loea, ikaika loa kēia lāʻau lapaʻau. Kōkua ia i ka wikiwiki, hiki ʻole i ka hōʻemi ke ʻano o ke kino. Aia, ʻoiaʻiʻo, nā hui kikoʻī. Akā inā ʻoe e loiloi i ka pae kumukūʻai o ke kumukūʻai, a laila pili ka lāʻau i ho'ākāka ʻia ma kēia mea i hōʻoia pono iā ia iho.

Ua nānā mākou i nā ʻōlelo noi a me nā loiloi no Mikardis Plus.

Me ka hana pūnāwai paʻa ʻole

Ma ke alo o kahi pōʻino nui (CC ma lalo o 30 ml / min), ua kuhi ʻia ʻo Mikardis Plus.

Me ka mālama aka, pono e hoʻohana i kahi mea hypotensive e kū'ē ai i ke kua o ka stenosis artery o ka lāʻau hoʻokahi wale nō a i ka bilateral renal artery stenosis a ma ke kūlana ma hope o ka hiki ʻana i ka pēpē. I nā mea maʻi me ka hoʻohaʻahaʻa kino ʻole 'aʻai (CC ma luna o 30 ml / min), ʻaʻole pono ka hoʻoponopono ʻana o ka Mikardis Plus, akā, nānā lākou i ka nānā ʻana i ka hana renal.

Me ka hana pūpū hemahema

Ke hele nei i nā hōʻino koʻikoʻi o ka ate (ka papa C ma ke kiʻekiʻe Child-Pugh), he contraindicated ke hoʻohana ʻana o Mikardis Plus.

ʻO nā mea maʻi me nā maʻi ʻōlima kūpono a i ʻole nā ​​maʻi o ka pōmaikaʻi holomua (ʻO ke keiki a me Pugh kahi A a me B) pono e hoʻohana i ka lāʻau lapaʻau me ka makaʻala, ʻoiai me nā loli liʻiliʻi o ka palau wai-electrolyte, hoʻonui ʻia ka ulu ʻana o ka coma hepatic. I ka hihia o nā hana hōʻemi kino o ka maʻi o ka leʻaleʻa / maʻalahi, ʻaʻole pono ka nui o ka nui o kēlā me kēia lā o Mikardis Plus e hoʻonui ʻia 40 / 12.5 mg.

ʻO ka waiho ʻia ʻana o Mikardisplyus, hoʻopiha i ka lāʻau lapaʻau a me nā ʻano.

ʻO nā papa ʻulaʻi, he biconvex, ʻelua-papaha (hoʻokahi papula he pinkish-beige i ke kala, ʻoi aku ke keʻokeʻo ma ka ʻoni me nā komo ʻana o ka poni-ʻula-ʻula), ma ka wai ke māka i ka hōʻailona ʻo "H4" a me ka hōʻailona ʻoihana. 1 kōpō telmisartan 40 mg hydrochlorothiazide 12.5 mg
Nā mea kūʻokoʻa: povidone, meglumine, sodium hydroxide, sorbitol, magnesium stearate, microcrystalline cellulose, red iron oxide, sodium starch glycolate, lactose monohydrate, mais starch.
7 pcs - nā kāmele (2) - nā kīʻaha o ke kāleka.
7 pcs - nā kāmele (4) - nā ʻeke pepa.
7 pcs - nā kāmele (8) - nā kīʻaha o ke kāleka.
7 pcs - ʻōmole (12) - nā kāʻei o ke kāleka.
ʻO nā papa ʻulaʻi, he biconvex, ʻelua-papaha (ʻo kekahi papala he pinkish-beige, ʻoi aku ke keʻokeʻo me nā mea ʻē aʻe me ka pinkish-beige), ma ka keokeo ka mākaʻina ʻo "H8" a me ka hōʻailona o ka hui. 1 kōpō telmisartan 80 mg hydrochlorothiazide 12.5 mg
Nā mea kūʻokoʻa: povidone, meglumine, sodium hydroxide, sorbitol, magnesium stearate, microcrystalline cellulose, red iron oxide, sodium starch glycolate, lactose monohydrate, mais starch.
7 pcs - nā kāmele (2) - nā kīʻaha o ke kāleka.
7 pcs - nā kāmele (4) - nā ʻeke pepa.
7 pcs - nā kāmele (8) - nā kīʻaha o ke kāleka.
7 pcs - blisters (14) - nā ʻeke pepa.

Kahi ʻia ka wehewehe ʻana o ka lāʻau lapaʻau ma luna o nā kuhikuhi i pili i ka hoʻohana.

Kūmole lāʻau lapaʻau Mikardisplyus

ʻO ka lāʻau antihypertensive. ʻO ia ka hui pū ʻana o ka telmisartan (kahi aniotistin II receptor antagonist) a me hydrochlorothiazide - kahi diuretic thiazide. ʻO ka hoʻohana pinepine ʻana i kēia mau māhele i alakaʻi i kahi hopena antihypertensive nui aʻe ma mua o ka hoʻohana ʻana o kēlā me kēia. Hoʻomaopopo ka MikardisPlyus 1 manawa / lā i kahi hōʻoli nui o ke kahe koko.
He telagonist kikoʻī ʻo Telmisartan o ka ʻĀkau e huhū ana i ka ʻā. He wahi kūlana kiʻekiʻe ia no ka AT1 receptor subtype o ka angiotensin II, kahi i ʻike ʻia ai ka hana a ka angiotensin II. Hoʻololi ʻo Telmisartan angiotensin II mai kona mākaʻikaʻi ʻana i ka mea nāna i hopu, me ka nele i ka hana a kahi agonist e pili ana i kēia receptor. Hoʻopili wale nei ʻo Telmisartan i ka subpipe AT1 receptor o ka angiotensin II. Ke hoʻomau nei ka ʻili ʻana. ʻAʻole i pili ka Telmisartan i nā mea hoʻohana ʻē aʻe (e komo pū ana me nā mea ʻae o AT2) o ka angiotensin. Ka hana koʻikoʻi o kēia mau mea nānā, a me ka hopena o ko lākou hiki ke hoʻoulu ʻia me ka angiotensin II, ke ʻano o ka piʻi ʻana me ke koho ʻana i ka telmisartan, ʻaʻole i aʻo ʻia ʻia. Ke alakaʻi nei ʻo Telmisartan i kahi emi o nā pae ald testosterone. ʻAʻole paʻa ʻo Telmisartan i ka renin i loko o ke kahe a me nā kaila wai, ʻaʻole paʻa i ka ACE, ʻaʻole hana i ka bradykinin.
I nā mea maʻi me ka hypertension arterial, hoʻemi ka telmisartan i ka hoʻokahe koko systolic a me ka diastolic, me ka hoʻopi ʻole ʻana i ka hapa o ka puʻuwai.
ʻO Telmisartan ma ke ʻano o 80 mg mau poloka i ka hopena hypertensive o ka angiotensin II. ʻO kāna hana e mau ma mua o 24 mau hola, ʻoiai me nā hola 4 hou ma mua o ka lawe ʻana i ka hopena hou aʻe. Hoʻomaka ʻia ka hoʻomaka ʻana o ka hana hypotensive ma loko o 3 mau hola ma hope o ka hoʻokele mua o ka telmisartan. I ka hihia o ka hōʻano pani ʻana o ka telmisartan, pane iki ka maʻi koko i kona pae kumu me ka ʻole o ka hoʻomohala ʻana i ka maʻi withdrawal.
ʻO ka Hydrochlorothiazide kahi diuretic thiazide. Hoʻopilikia ka Thiazide diuretics i ka reabsorption o nā electrolytes i loko o nā renal renal, e hoʻonui pinepine i ka hoʻonui ʻana o ka sodium a me nā chlorides (ma kahi kokoke i nā helu like). Hoʻonui ka hopena diuretic o ka hydrochlorothiazide i ka hoʻohaʻahaʻa i ka bcc, kahi hoʻonui i ka hana renin plasma, hoʻonui i ka huna ʻana o ka aldosterone a hele pū ʻia me ka piʻi ʻana o ka paʻakai urine a me ka bicarbonates, a me hypokalemia hoʻi. Me ka hoʻomohala pinepine ʻana o ka telmisartan, aia ka manaʻo e hoʻōki i ka nalowale o ka pākani i kumu ʻia e nā diuretics nei, ma muli paha o ka blockade o ka ʻina renin-angiotensin-ald testosterone.
ʻO ka hoʻohana wā lōʻihi o ka hydrochlorothiazide e hōʻemi i ka hopena o ka hoʻopiʻi o ka maʻi cardiovascular a me ka make ma o lākou nei.
Ma hope o ka lawe ʻana i ka hydrochlorothiazide, hoʻonui ʻia ka diuresis ma hope o 2 mau hola, a nānā ʻia ka hopena nui loa ma hope o nā hola 4. ʻO ka hopena diuretic o ka lāʻau e hoʻomau nei no nā hola 6-12.
ʻO ka hopena antihypertensive kiʻekiʻe o MikardisPlus e hana pinepine i nā 4 wiki ma hope o ka hoʻomaka ʻana o ka hoʻomaʻamaʻa.

ʻO ka dosis a me ke ala o ka hoʻokele lāʻau.

Lawe ʻia ʻo MikardisPlus i kahi manawa 1 i ka lā / lā, e pili ana i ka ʻai i ka meaʻai.
Hiki ke kuhikuhi ʻia ʻo Mikardis Plus 40 / 12.5 mg i nā maʻi i hiki i ka hoʻohana ʻana o ka Mikardis ma kahi o 40 mg a i ʻole ka hydrochlorothiazide e alakaʻi i ka lawa o ke kahe koko.
Hiki ke kuhikuhi ʻia ʻo Mikardis Plus 80 / 12.5 mg i nā maʻi i hiki i ka hoʻohana ʻana o ka Mikardis ma kahi o 80 mg a i ʻole ʻo Mikardis Plus 40 / 12.5 mg, ʻaʻole i alakaʻi i ka hiki ke lawa o ke koko.
Me ka hana ʻole o ka palalima ʻole a i ʻole ka hopena, ʻaʻole pono nā loli ʻana. I nā poʻe maʻi āpau, pono ka nānā ʻana o ka mālamalama.
I nā mea maʻi me ka pīhoihoi hōʻemi a me ke ʻano maʻalahi, ʻo MikardisPlus, ʻaʻole pono e hoʻohana i ka lā maʻamau i kēlā me kēia lā ma mua o 40 / 12.5 mg.
ʻAʻole koi ʻia nā loli i loko o ka noho ʻai ʻana i nā maʻi maʻi ʻelemakule.

Loaʻa iā Mikardisplyus:

ʻO nā hopena ʻaoʻao e manaʻo ʻia mai ka ʻike me ka telmisartan
Mai ka papa hana hanu: nā maʻi ʻana o ka ʻōpū hanu o luna (kahi a me ka bronchitis, pharyngitis, sinusitis), pōkole o ka hanu.
Mai ka pūnaehana cardiovascular: bradycardia, tachycardia, hōʻailona hōʻailona i ka emi o ke kahe koko, ke ʻeha o ka umauma.
Mai ka ʻaoʻao o ka pūnaehana nīnaena waena a me nā ʻōnaehana hoʻoneʻe peripheral: excitability, kahi manaʻo makaʻu, ke kaumaha, kaumaha, nāwaliwali, a me ka insomnia.
Mai ka pūnaehana hana ʻana: ka waha maloʻo, utuloli, puʻu, a me ka hana i ʻole e hoʻopā ai.
Mai ka pūnaehana urinary: failed renal failed.
Mai ka pūnaehana endocrine: ka nalowale o ka kaohi o ke kiʻekiʻe o hypoglycemia i ka maʻi diabetes mellitus, ka hoʻohaʻahaʻa glucose iki.
Mai ka pūnaehana hemopoietic: eosinophilia, hoʻemi ʻia ka hemoglobin, thrombocytopenia.
Mai ka pūnaehana musculoskeletal: arthralgia, arthrosis, ʻeha i ka ʻeha, nā ʻeha ʻeha lalo, myalgia, koʻo twulching o nā ʻUā keiki bipi (krampi), nā hōʻailona e like me ka tendonitis, nāwaliwali.
Mai nā mea aneʻomanaʻo: poluity ʻike maka, vertigo.
Mai ka ʻaoʻao o ka hana o ka metabolism: hypercholisterinemia, hyperuricemia, hypokalemia, hyperkalemia, hypercalcemia, hoʻonui i nā pae o ka uric acid, ka mea hana, mea enima, nā kōkō.
Nā hui kūloko: eczema, erythema, pruritus, angioedema, urticaria a me nā hopena ʻē aʻe (e like me ka hihia o ka hoʻohana ʻana o ka angiotensin II antagonist).
Nā mea ʻē aʻe: nā maʻi like-flu, hoʻonui i ka luhū, hōʻemi i ka potency.
ʻO nā hopena ʻaoʻao ka mea i manaʻo ʻia mai ka ʻike me ka hydrochlorothiazide
Mai ka papa hana hanu: dyspnea, ʻeha hōʻeha o ka ʻōpū hanu (me nā pneumonia a me ka edema pulmonary).
Mai ka pūnaehana cardiovascular: arrhythmias, orthostatic hypotension, necrotic angiitis.
Mai ka ʻaoʻao o ka pūnaehana neʻe: ʻo ka pīhoihoi, a me ka hopohopo, ke kaumaha nei, ka manaʻo o ka hopohopo, e kū ana i ka wā e hele ana, paresthesia.
Mai ka papa hana ʻana: ʻeha o ka ʻōpū, ka ʻōpū, ka dyspepsia, gastritis, anorexia, ka make ʻana o ka makemake, sialadenitis, constipation, pancreatitis, hana i nā aʻolo lewa, jaundice (hepatocellular a cholestatic).
Mai ka pūnaehana endocrine: ka nalowale o ka kaohi o ke kiʻekiʻe o hypoglycemia i ka maʻi diabetes mellitus, ka hoʻohaʻahaʻa glucose iki.
Mai nā papa inoa sensory: transient blurred vision, xanthopsia, vertigo.
Ma ka ʻāpana o ka metabolism: hypercholisterinemia, hyperuricemia, hypokalemia, hyponatremia, kahi hoʻemi ʻana ma BCC, ʻaila metabololamania kīnāwai, hyperglycemia, hoʻonui i ka triglycerides, glucosuria.
Mai ka pūnaehana hemopoietic: anemia aplastic, anemia hemolytic, ʻokiʻoki o ka iwi hematopoiesis sumsone, leukopenia, neutropenia, agranulocytosis, thrombocytopenia.
Mai ka pūnaehana urinary: nā maʻi o ka ʻōnaehana urinary, interstitial nephritis, impalired renal function.
Mai ka pūnaehana musculoskeletal: nawaliwali, māhuahua o ka ʻiʻo.
Nā ʻano maʻi: anaphylactic reaction, eczema, lupus-like reaction, vasculitis, photosensitivity reaction, rash, exacerbation of the skin manifest of SLE, toxic epidermal necrolysis, angioedema, urticaria a me nā ʻano like ʻole (e like me ke ʻano o ka hoʻohana ʻana o ka angiotensin II antagonists).
Nā mea ʻē aʻe: nā maʻi lewa e like me ka maʻi, ka maʻi, ka kaila o ka potency.

ʻO nā ʻōlelo kūikawā no ka hoʻohana ʻana o Mikardisplyus.

I nā mea maʻi me ka hana aho o ka pehu a me ka maʻi ʻōpiopio holomua, pono ʻo MikardisPlus e mālama me ka akahele, no ka mea, ʻo nā loli liʻiliʻi o ka pauna wai-electrolyte hiki ke kōkua i ka hoʻomohala ʻana i ka comp hepatic.
I nā mea maʻi me ka stenosis renalal renal stenosis a i ʻole ka stenosis arterial o ka ʻola wale ʻana e hana ai, ka hoʻohana ʻana i ka telmisartan e hoʻonui i ka ʻeha o ka hypotension arterial koʻikoʻi a me ka hana ʻole ʻole.
ʻAʻoheʻike i loaʻa me MikardisPlus i nā maʻi me nā maʻi renal impaired koʻikoʻi a i ʻole nā ​​mea maʻi ma hope o ka hoʻololi ʻana i nā keiki. Mai ka mea e ʻike ai i ka hoʻohana ʻana iā MikardisPlus i ka poʻe maʻi me ka liʻiliʻi o ka hana hanal i hōʻemi ʻia ka liʻiliʻi, i loko o ia mau hihia, ua ʻōlelo ʻia ka manawa maʻamau o ka potassium serum a me nā pae creatinine. ʻO ka hoʻohana ʻana o ka hydrochlorothiazide i nā maʻi me nā maʻi lōkuhi i hana ʻole ʻia ka hiki ke alakaʻi i ka azotemia. Hoʻomaopopo ʻia ka nānā ʻana no ka hana ʻana i nā hana o ka lolo
ʻO nā mea maʻi me ka hoʻohaʻahaʻa i ka BCC a me / a i ʻole hyponatremia e hua ana i ka nui diuretic therapy, ka palena o ka paʻakai ʻana o ka paʻakai, ka ʻeha ʻana, a i ʻole ka luaʻi paha e hoʻomohala i ka maʻi hypotension arterial maʻi, ʻoi aku ma hope o ka lawe ʻana i ka hopena mua o ka lāʻau. Ma mua o ka hoʻohana ʻana iā MikardisPlus, pono ke hoʻoponopono ʻana i kēia mau maʻi.
I nā hihia i hilinaʻi nui ʻia ai ke kani vascular a me ka hana o ka renal i ka hana a ka ʻōnaehana renin-angiotensin-aldosterone (no ka laʻana, i nā mea maʻi me ka hōʻeha puʻuwai koʻikoʻi a i ʻole nā ​​mea laikini concomitant, e komo pū me ka stenosis renal), ka hoʻohana ʻana o nā lāʻau lapaʻau, ka mea e pili ana i ka kūlana o kēia ʻōnaehana, hiki ke ukali pū ʻia e ka hoʻomohala ʻana o ka maʻi hypertension arterial, hyperazotemia, oliguria, a i ʻole ma nā hihia līlū, nā maʻi renal maʻamau.
I ka poʻe maʻi me ka aldosteronism maʻamau, nā lāʻau antihypertensive, ka hana o ka hana o ka mea e pale ai i ka hana o ka renin-angiotensin-ald testosterone, ka mea maʻamau. I kēlā mau kūlana, ʻaʻole i aʻo ʻia ke koho ʻana o MikardisPlus.
I ka poʻe maʻi me ka stenosis aortic a mitral a i ʻole he obventive hypertrophic cardiomyopathy, hoʻohana ʻia ʻo MikardisPlus (e like me nā vasodilator ʻē aʻe) pono ka mālama kūikawā.
ʻO ka hoʻohana ʻana o ka diuret thiazide e hoʻonāukiuki i ka hoʻohaʻahaʻa glucose.
I nā maʻi me ka maʻi mellitus, e koi ʻia nā loli o ka nui o ka insulin a i ʻole a me nā hypoglycemic waha. I ka wā o ka mālama ʻana me ka hydrochlorothiazide, hiki ke hōʻike ʻia kahi ʻano latent o ka maʻi maʻi.
I kekahi mau hihia, hiki i ka hoʻohanaʻana o hydrochlorothiazide ke ulu i ka hyperuricemia a me ka gout.
Ke hoʻohana ʻia ʻo MikardisPlus, pono ka hoʻoholo ʻana o ka nui o ka pae o nā electrolytes i ka serum koko.
Thaizide diuretics, incl. Hiki i nā hydrochlorothiazide ke hoʻopilikia i ka kaulike o ka electrolyte me ka KShchR (hypokalemia, hyponatremia a me hypochloremic alkalosis). ʻO nā ʻōmaʻomaʻo o kēia mau pilikia ka mālamalama, makewai, nāwaliwali laulā, ka lethargy, ka hiamoe, ke kaumaha, ka myalgia a i ʻole ka twitching o nā musuli keiki, nāwaliwali o ka naʻau, ka ʻimi o ka arterial, oliguria, tachycardia, nausea, a i ʻole ka luaʻi.
Ke hoʻohana nei i ka hydrochlorothiazide, hiki i ka hypokalemia ke hoʻomohala, akā hiki i ka telmisartan i ka manawa like ke hōʻemi i kēia hōʻeha. ʻO ka nui o ka hopena o ka hypokalemia ka mea nui loa i ka poʻe maʻi me ka cirrhosis, me ka nui o ka diuresis, me ka uku ʻole o ka waha o ka electrolytes, a me ka hopena o ka hoʻohana like ʻana o GCS a i ka ACTH. ʻO Telmisartan, ʻo ia kahi o MikardisPlus, ma ka ʻaoʻao ʻē aʻe, hiki ke alakaʻi i ka hyperkalemia ma muli o ka antagonism i ka ʻĀina e like me nā angiotensin II. ʻOiai ʻaʻole i hōʻike ʻia ka hyperkalemia koʻikoʻi i ka hoʻohana ʻana o ka Mikardis Plus, pono e hoʻomanaʻo ʻia i nā mea pili i ka ulu ʻana no ka hoʻomohala ʻana a me / a me nā hemahema a me ka maʻi mellitus mellitus.
ʻAʻohe mea iʻike i hiki iā MikardisPlus hiki ke hōʻemi a pale paha i ka hyponatremia i kumu e ka diuretics. He liʻiliʻi ka liʻiliʻi o ka chloride a ʻaʻole pono e mālama i ka mālama ʻana.
Hiki i ka Hydrochlorothiazide ke hōʻemi i ka excretion calcium a me ke kumu (i ka ʻike ʻole ʻana o ka hana ʻoluʻolu o nā kaila ʻona o kēia neona) he loli a me ka liʻiliʻi o ka nui o ka pae o ka serum calcium. ʻO nā hypercalcemia koʻikoʻi nui paha kahi hōʻailona o ka hyperparathyroidism latent. Ma mua o ka hoʻoholo ʻana i ka hana o nā kihi parathyroid, pono e hoʻomaʻule ʻia ka thiazide diuretics.
Ua hōʻike ʻia e hoʻonui nui ʻia e ka hydrochlorothiazide i ka hoʻopiha o ka magnesium i loko o ka huki, hiki iā ia ke hana i ka hypomagnesemia.
I ka poʻe maʻi me ka ischemic cardiopathy a i ʻole ka maʻi naʻau coronary, kekahi lāʻau antihypertensive i loko o ka hihia o ka hopena nui o ke kahe koko hiki ke alakaʻi i ka myocardial infarction a i ʻole stroke.
ʻO ka ʻōlelo i hāpai ʻia i kēlā me kēia lā ʻo Mikardis Plus 40 / 12.5 a i ʻole 80 / 12.5 he 169 a 338 mg o sorbitol, ia manawa. No laila, ua hoʻonāukiuki ʻia ka lāʻau i nā mea maʻi me ka intolerance fructose hoʻoilina.
Hiki i nā maʻi hypersensitivity ka hydrochlorothiazide, keu i nā mea maʻi me ka mōʻaukala o allergy a bronchial asthma.
Hiki iā MikardisPlus, inā pono, e hoʻohana pū ʻia me kekahi lāʻau lapaʻau antihypertensive.
Ke hui pū me ka Mikardis Plus, pili ka diuretics pili i ka paʻakai, ka laxatives, corticosteroids, ACTH, amphotericin, carbenoxolone, penicillin G (sodium salt), waikawa salicylic a me nā mea e pili ana iā ia, ka mālama pinepine ʻana o ka paʻakai i ka plasma koko.
Me ka hoʻohana pū ʻana o Mikardis Plus a me ka diuretics pākeleka o ka potassium, ka hoʻomākaukau ʻana i ka paʻakai, nā lāʻau lapaʻau ʻē aʻe hiki ke hoʻonui i ka paʻakai pākela i loko o ke koko serum (no ka laʻana, he sodium heparin), a i ʻole ke hoʻololi ʻana i ka sodium chloride me nā paʻakai pāhaʻi, mālama pinepine ʻia ke ʻano o ka paʻakai i ka plasma koko.
Inā makemake ʻoe e hoʻohana i ka hoʻomākaukau ʻana o ka calcium, pono ʻoe e kiaʻi pinepine i ka paʻa o ka calcium i ke koko a, inā pono, e hoʻololi i ka ʻano o kēia mau lāʻau.
Hoʻohana ʻo Pediatric
ʻAʻole paʻa ka hopena a me ka palekana o ka hoʻohana ʻana o MikardisPlus i nā keiki a me nā ʻōpio ma lalo o nā makahiki 18 he mau makahiki.
Hoʻokomo i ka hiki ke lawe i nā kaʻa a kāohi i nā mīkini
ʻAʻole i mālama ʻia kahi noiʻi kūikawā o ka hopena o ka lāʻau lapaʻau ma ka hiki ke pana i kahi kaʻa a hana pū me nā mīkini hoʻokō. Eia nō naʻe, i ke kaʻa ʻana i ke kaʻa a me ka hana pū me nā mīkini, pono e hoʻomanaʻo ka mea i hiki ke hoʻomohala i ka mahanilo a me ka pohō i ka wā e hoʻohana ai i ka lāʻau MikardisPlus.

Lapaʻau

ʻO Mikardis Plus ka hui ʻana o ka telmisartan a me ka hydrochlorothiazide. Me kā lākou hui pū ʻana, hoʻomaka kahi hopena antihyertonic ikaika. ʻO ka hopena, ua ʻike ʻia kahi emi ʻana i ke kaomi.

ʻO Telmisartan kahi mea koho ʻokiʻoki ma ke ʻano he 2 blocker blocker. Ke hoʻomau nei ka ʻili ʻana. Eia kekahi, hiki i kēia māhele ke hōʻemi i ke kāpiliʻana o ald testosterone.

ʻO ka Hydrochlorothiazide kahi diuretic thiazide-type. Hoʻopilikia ia i ka hoʻihoʻi ʻana o nā electrolytes i loko o nā ʻōpala o nā keiki, hoʻonui i ka hoʻonui ʻana o ka sodium chloride mai ke kino. Hoʻolaha nui kēia i ka nui o ka kaila o ke koko, hoʻonui i ka synthesis o aldosterone, hoʻonui i ka hana renin.

Ma hope o ka hoʻoponopono waha ʻana o ka hydrochlorothiazide, e piʻi ka diuresis i kekahi mau manawa, a loaʻa ka hopena nui loa ma hope o kekahi mau hola a mau i nā hola 12.

Hoʻohui nūhou

Nā pilina e hiki ke hui pū me ka hoʻohana pū ʻana o ka telmisartan me nā lāʻau lapaʻau a me nā mea lapaʻau hou:

• ʻO ka hydrochlorothiazide, warfarin, digoxin, simvastatin, glibenclamide, amlodipine: ʻaʻole i loaʻa ka launa hou ʻana i ka lapaʻau, ʻike nui i ka ʻai o ka plasma o ka moka i loko o ke koko e pili ana i ka 20% ua ʻike ʻia, me ka hoʻohana pū ʻana o telmisartan a me digoxin, ua ʻōlelo ʻia i kēlā me kēia manawa me ka hoʻoholo ʻana i ka pae o ka hopena i loko o ke koko,
• Hoʻomoe lithium: i nā hanana lohi, hiki ke hoʻololi ʻia i ka ʻatikā lithium ma ke koko hiki, ke hoʻomau ʻia me nā hopena o nā mea hoʻonaninani, pili i ka mea e kiaʻi ai lākou i ka serum.
• nā lāʻau lapaʻau antihypertensive ʻē aʻe: e hoʻonui paha ka hopena antihypertensive, me ka hui pū ʻana o ka telmisartan a me ramipril, ua hoʻonui ʻia ka AUC_0-24 a C_max ka hope a me kona metabolite (ramiprilat) 2.5 mau manawa, ʻaʻole maopopo ka ʻike koʻikoʻi o kēia pili.
• Non-steroidal anti-inflammatory drugs (NSAIDs), me ka acetylsalicylic acid, i hoʻohana ʻia me he mea hoʻohana anti-inflammatory (i loko o kahi lā i kēlā me kēia lā ʻaʻole ʻoi aku i ka 3 g): nā mea hoʻohana ʻole i koho ʻia a me nā cyclooxygenase-2 inhibitors (COX-2) i nā mea maʻi me ka hōʻemi i ka BCC hiki ke alakaʻi i ka hoʻomohala ʻana i ka pilikia ʻoi aku ka hopena. , nā mea lawelawe e hoʻopili ai iā RAAS e hōʻike i kahi hopena sinner, me ka hoʻohui pū ʻana o ka telmisartan a me nā NSAID i ka hoʻomaka ʻana o ka maʻi, pono ia e uku no ka bcc a hoʻopaʻa i ka hana renal, me kēia hui pū kekahi ma ka inhibiting prostaglandin vasodilator hana o ka telmisartan, he emi ia ka wā hui me ka paracetamol a ibuprofen clinically nui ai ua i hoikeia.

Hiki i nā pilina pili me ka hoʻohana pū ʻana o ka hydrochlorothiazide me nā mea lapaʻau a me nā mea lapaʻau hou:

• antidiabetic waha waha a me ka insulin: e hoʻoponopono pono ʻia ka hoʻoponopono ʻana o kēia mau lāʻau.
• barbiturates, analio opioid, ethanol: ua hoʻoweliweli ʻia ka hoʻoweliweli o ka hypthension orthostatic,
• colestyramine, colestipol: ua hoʻokaʻawale ʻia ka hoʻopili ʻana o ka hydrochlorothiazide,
• metformin: hoʻonui i ka hopena o ka lactic acidosis,
• Pressor amines (e pili ana i ka norepinephrine): hiki i ka nāwaliwali o ka hana a kēia mau mea ke hiki,
• ʻO ka glycosides cardiac: hoʻopilikia i ka hōʻemi i ka hoʻouluʻana i ka hypomagnesemia / hypokalemia ma muli o ka diuret thiazide, a me ke ʻano o ka arrhythmias i kumu o ka hoʻohana ʻana o nā glycosides cardiac, hoʻopiʻi ʻia
• hoʻomaha ʻole i ka hoʻomaha relous (me ka tubocurarine chloride): hiki ke hoʻonui ʻia i ka hana a kēia mau mea āpau,
• Hoʻomake ka calcium: hoʻonui ʻia ke kiʻekiʻe o ka calcium ma muli o kahi hoʻohaʻahaʻa ʻana i ka hoʻonui ʻia e nā keiki, me kēia hui pū ʻana, pono ia e kiaʻi pinepine i ka neʻe o ka calcium ma ke koko a, inā pono, e loli i kona ʻano
• anti-gout agents: hiki ke hoʻonui ʻia ka nui o ka wa o ka uric acid i loko o ka serum koko, hiki iā ia ke koi ʻia i ka hoʻoponopono nui ʻana o nā māpē uricosuric, he hoʻonui i ka piʻi o nā hopena hypersensitivity i allopurinol e hoʻomaopopo ʻia,
• nā biperidine, ka atropine a me nā lāʻau m-anticholinergic: nā nāwaliwali o ka gastrointestinal palupalu, bioavailability o ka diuretics thiazide, ua hoʻonui ʻia,
• diazoxide, beta-blockers: e hoʻonui i ka hyperglycemia i kumu o kēia mau lāʻau,
• laxatives, diuretics e hoʻoneʻe ana i ka potassium, gluco- a me mineralocorticosteroids, amphotericin B, corticotropin, benzylpenicillin, carbenoxolone, derivatives o ka acetylsalicylic acid a me nā lāʻau lapaʻau ʻē aʻe e alakaʻi ana i ka hoʻonui ʻia ʻana o ka pāhare pākuʻi a me ka hoʻomohala ʻana i ka hypokalemic: Telmisartan
• Nā NSAID: hiki i ka nāwaliwali nā antihypertensive a me nā hopena diuretic,
• Hoʻomaha pākaha, potoma-sparing diuretics a me nā mea hana ʻē aʻe e alakaʻi ana i ka hoʻonui ʻana i ka pae o ka pāhana i loko o ka serum koko (heparin), ke hoʻololi hou ʻana o ka paʻakai pākia me ka paʻakai pālala me ka paʻakai pālule: ʻike ʻia ka helehelena o ka hyperkalemia, nānā ʻia ka manawa o ka hoʻoliʻi ʻana o ka paʻila o ka pāhana i loko o ke koko.
• ʻo nā huaʻai cytotoxic (e ..g. cyclophosphamide, methotrexate): ua hoʻōla nui ʻia nā hana a kēia mau lālā a ua hoʻonui ʻia ko lākou hopena myelosuppressive,
• ka glycyrrhizic acid (licorice root): kahi hōʻemi ʻana i ka nui o ka pāhana i loko o ka serum koko e hiki ana (ka hoʻomohala ʻana o ka hypokalemia),
• amantadine: hiki i ka hopena o nā hopena i makemakeʻoleʻia e ka mea a kēia mea i hoʻonui.

Nā analogues a Mikardis Plus ʻo: Telzap Plus, Telsartan N, Telpres Plus, etc.

Ke ʻano o ka hoʻokele ʻana a me ka palaila

Hōʻike ka ʻōlelo no ka lawe ʻana i kēia lāʻau lapaʻau i hoʻokahi papa hoʻokahi i ka lā. ʻAʻole koʻikoʻi ka ʻai, akā ma kahi ʻōpū ʻole, ua pono ka hopena i nā manawa wikiwiki.

ʻO ka hopena kiʻekiʻe, e like me ke kānāwai, ua hoʻokō ʻia i loko o hoʻokahi a i ʻelua mau mahina ma hope o ka hoʻomaka ʻana o ka lāʻau lapaʻau. Inā loaʻa kahi makemake, a laila e hoʻopili ʻia i ka lāʻau lapaʻau me nā lāʻau ʻē aʻe e kōkua i ke kahe o ke koko i ka manawa pōkole.

No nā poʻe maʻi e loaʻa ana i ka hypertension koʻikoʻi, hiki i ke kauka ke hoʻonui i ka nui ma 160 mg i kēlā me kēia lā.

Hoʻolohe Hiki i ka Hydrochlorothiazide ke hoʻopilikia koʻikoʻi i ke kūlana hou o kahi mea i hōʻike mua ʻia i ka maʻi kino o ka maʻi. Me kēia maʻi, ʻoi aku ka maikaʻi o ka hoʻopuka ma ka diuretics loop.

4. Ka hui pū ʻana me nā ʻano ʻē aʻe

Me ka hoʻohui like ʻana o kēia ʻano lāʻau me:

1. Nā lāʻau antihypertensive - hiki ke nānā ʻia ka piʻi o nā hopena antihypertensive,
2. Hoʻomoe ka Lithium - ʻike pinepine ʻia ka manawa hoʻonaninani o kēia mahele i ke koko,
3. Digoxin - kahi hoʻolōʻihi i ka neʻe ʻana o ka hoʻokaʻina ʻana o ka māhele hope loa i ke koko e like me ka 20% e mahalo ʻia.
4. Me NSAIDs, ʻike iki ʻia kahi hana o ka pilikia ʻole i loko o nā mea maʻi me ka nui o ke koko holo ʻole.
5. Me nā barbirutes, nā mea hoʻopiʻi opioid - ʻike ʻia ka orthostatic hypotension,
6. Metformin - ka hopena lactic acidosis hiki mai
7. ʻO Colestipol a me colestyramine - ke kāohi ʻia ʻana o ka hoʻoulu ʻana o ka hydrochlorothiazide,
8. ʻO ka insulin a me ka hypoglycemic hoʻohanaʻole - hoʻonui i ka hana a nā mea hana hope,
9. Nā lāʻau lapaʻau anti-gout - nui paha ka hoʻonui ʻana i ka ʻike o ka uric acid i ke koko o kahi kanaka,
10. ʻO nā hoʻomaha hoʻomaha mus-non-depolarizing - ke ulu nei ka hoʻonuiʻana i ko lākou pono,
11. Kūleʻa ka calcium - hiki iā ʻoe ke nānā i kahi hoʻonui o ka calcium ma ke koko,
12. ʻO M-anticholinergics, no ka laʻana, biperiden a atropine paha - e hoʻonui i ka bioavailability o ka diuret th thiazide.

Pehea e lawe ai i kēia lāʻau i ka wā hāpai?

I ka wā hapai, pono ka haʻalele ʻana i ka hoʻokele waha o Mikardis Plus.

ʻO kēia ma muli o ka hōʻoia i nā mea ikaika e hiki ke komo i loko o nā mea liʻiliʻi liʻiliʻi, e hōʻike ana i ka hopena maikaʻi ma luna. Eia kekahi, hiki ke hana pū i ke kūlana maʻamau o ka makuahine.

I ka wā o ka umauma, pono ʻoe e kāpae i ka nui o ka lawe ʻana i ka lāʻau. Inā loaʻa kēia kūpono i ka ʻaila, a ʻaʻohe kūpono o nā ʻuhikahi i hiki, a laila pono e ʻānai ʻia nā keiki.

7. Kaʻi ʻana o ka lāʻau

Hoʻokomoʻia kēia lāʻau lapaʻau i loko o kahi keʻokeʻo pouli e pale ʻia mai ka umauma a me ka lohi o ka lā. Hiki i kahi wahi kūpono ke laka. Eia kekahi, pono ʻoe e hōʻoia e hāʻule ka lāʻau i loko o nā lima o nā keiki ʻōpio.

Pono e mālama i kēia lāʻau lapaʻa no nā makahiki ʻekolu aʻe. Inā makemake ʻia kēia lāʻau lapaʻau, a laila ʻaʻole ʻae ʻia kona hoʻohana hou ʻana.

No kēia mea hana, hiki ke loli ʻē aʻe ke kumukūʻai ma ia wahi. Aia nā kumukūʻai i lawe ʻia i nā kumukūʻai i lawe ʻia ma Moscow a me Kiev.

I Ukraine, pono ʻoe e uku iā 450 hryvnia no kēia lāʻau lapaʻau.

Pono e noʻonoʻo i ka kauka pono pono e hana me ke koho ʻana i ke kumu hoʻopaʻa, akā ʻaʻole ka mea maʻi.

Hiki ke hoʻololi ʻia kēia lāʻau lapaʻau e like me nā Diocor, Valzap Plus, Gizaar, Teveten Plus, Co-Diovan, Valsacor, Atakand Plus, Valz N, Lorista N, Lisinopril, Ibertan, Tareg, Blocktran, Cardosten, Vazotens, Losacor, Valsacor, Kandek , Norotivan, Lozarep, Renikard, Angiakand.

Inā loaʻa iā ʻoe kahi ʻike pilikino e hoʻohana ana i kēia huahana, a laila waiho i kahi loiloi e pili ana i kēia lāʻau lapaʻau.

ʻO nā loiloi o nā cardiologists e pili ana i ka lāʻau ʻo Mikardis Plus he konotation maikaʻi loa. Inā ʻaʻole ʻoe e hōʻole i ka dosage a hoʻomanawanui i ka hoʻokau ʻana no ka hele ʻana o nā maʻi i maʻi ai he contraindication e lawe ana iā Mikardis Plus, ma mua o ka hoʻomaka ʻana o kēia ʻano, ʻaʻole e lōʻihi ka hopena o ka hopena.

I kēia hihia, loaʻa pinepine nā hopena ʻokoʻa. Hoʻomaopopo nā Cardiologists i kahi hopena liʻiliʻi loa i ka piʻiʻana o ka puʻuwai. ʻOiai me ka hypertension koʻikoʻi, ʻike ʻia kahi hopena maikaʻi. ʻO ka hopena lōʻihi loa e pili ana iā 48 mau hola.

He maikaʻi maikaʻi nā loiloi maʻi e pili ana i ka lāʻau lapaʻau. ʻO nā wale wale nō o kēia lāʻau lapaʻau ke kumukūʻai. ʻO ka ʻoiaʻiʻo ʻaʻole ʻike nā kānaka a pau e uku i kēlā kālā no kēia pono hana.

E hoʻokuʻu i nā palapala a me ka ʻano

Hoʻohana ʻia ka lāʻau lapaʻau i ke ʻano o nā papa, kahi 2 mau pūnaehana ikaika - telmisartan a me hydrochlorothiazide.

E like me nā mea hoʻohui hou e hoʻomaikaʻi i ka wikiwiki a me ka hoʻopiha ʻana i ke kūoʻi ʻana o nā:

• ʻano keʻa mahina
• waiū waiū
• mikuleka
• sodium hydroxide
• waiona hao okses,
• povidone
• sorbitol
• Nā meglumine.

Hana ʻia nā papa ma kahi oval bx. ʻAʻole kahi mea antihypertensive e hoʻomaʻamaʻa ʻia ma ke ʻano o kahi pakanō, gel, a i ʻole nā ​​makua.

Hoʻohana ʻia ka lāʻau lapaʻau i ke ʻano o nā papa, kahi 2 mau pūnaehana ikaika - telmisartan a me hydrochlorothiazide.

Pūnaehana pīhoihoi waena

Me kahi minamina o ka pūnaehana neʻe i waena a me ka hoʻomohala ʻana i ka pilikia o ka noʻonoʻo i kekahi kanaka, ua loli ke ʻano hoʻohālike - kahi ʻāina kaumaha, ʻike i ke ʻano hopohopo.

ʻO ka ʻeha, ka ʻeha, ka paresthesia, ka nāwaliwali laulā, nā pilikia hiamoe.

Hoʻopilikia i ka hiki ke mālama i nā mīkini

ʻAʻole pili ka lāʻau lapaʻau i ka hana o ke ʻōnaehana kūlohelohe a me nā mākaʻi maikaʻi. I ka manawa like, pono ia e makaʻala i nā mea pale i ka wā e hana nei me nā mīkini paʻakikī a i ke kaʻa ʻana aku i kahi kaʻa, no ka mea hiki ke nalowale i ka ʻike ʻana, nā hiʻohiʻona o nā ʻaoʻao o ka ʻaoʻao (drowsiness, dizziness). Hiki i nā hopena maikaʻi ke hoʻoemi i ka ʻike o ka nānā a me ka wikiwiki o ka hopena psychomotor pono no ka hoʻokuke.

Hoʻohana i ka wā hāpai a me ka lactation

ʻO nā wahine i ka wā hāpai ua pāpā ʻia i ka lawe ʻana iā Mikardis i pili i ka hiki ke hiki i nā mea kūpono no nā kāne.

Ma ke kaʻina o ka hoʻolālā embryonic, hiki i ka hoʻopau ʻana i nā ʻōkene cardiovascular a me nā urinary.

Ke hoʻokomo nei i ka lāʻau lapaʻau lāʻau, pono ia e hōʻoki i ka umauma.

Ke hoʻokomo nei i ka lāʻau lapaʻau lāʻau, pono ʻo Mikardis Plus e ho'ōki i ka umauma.

Cardiologists

Elena Bolshakova, cardiologist, Moscow

Ua hana wau i kahi haʻawina ma ke ʻano he dissertation i ka hopena o ka lāʻau lapaʻau, no laila hiki iaʻu keʻike wiwoʻole e pili ana i ka hopena o Mikardis. Ke kōkua nei ka lāʻau lapaʻau e hoʻopaʻa i ka pīkoi ʻana o ka pīpī ma waena a hōʻemi i ka wikiwiki o ka hoʻomāhao o nā nalu cardiac, kahi e hoʻonāukiuki ai i ka hoʻomohala ʻana o nā maʻi cardiovascular Maʻa ka lāʻau lapaʻau e pono ai no ka poʻe ʻōpio a no ka poʻe pākeke. ʻO nā hopena ʻokoʻa e koi ai i ka hiki ke hoʻololi ʻia, ma ka hoʻomaʻamaʻa ʻole ʻaʻole i hālāwai. ʻAʻole pili ka lāʻau lapaʻau i ka ʻike.

Sergey Mukhin, cardiologist, Tomsk

Manaʻo wau he ala maikaʻi ka lāʻau lapaʻau e hōʻemi i ke koko kiʻekiʻe. Ke kiʻi ʻia i ka lā hoʻokahi, e hoʻomau ka hopena therapeutic i hoʻokahi lā. Ua kiʻekiʻe ke kumukūʻai. ʻO kahi papa nui o nā contraindications. Akā maikaʻi ka lāʻau lapaʻau no nā maʻi maʻi type 2, paʻa i ka maʻi naʻau coronary. Hāʻawi ʻia ka hoʻohana ʻana i nā maʻi me ka puʻuwai naʻau ʻole. Loaʻa nā maʻi kūloko i nā maʻi kuʻuna.

Hiki ke hoʻololi ʻia ʻo Mikardis Plus me Pritor, ka mea i mālama ʻia ma kahi wahi i kaawale ai mai ka radiation ultraviolet i ke mahana o + 8 ... + 25 ° C.

ʻO Dmitry Gavriilov, 27 makahiki, Vladivostok

Hoomaka ka hypertension arterial, ma muli o ke ahiahi aia ka pōloli maikaʻi, ka nele o ka ea, a hoʻomohala ʻia ka arrhythmia. Ua kuhikuhi nā Kauka i nā papa Mikardis. Ua hoʻomaka ka lāʻau lapaʻau e hana i ka lā mua. 3 mau hola ma hope o ka lawe ʻana i nā papa, ua hoʻomau ʻia ke kaumaha no nā hola 20 i hala aʻe. I kēia hihia, he mea nui e lawe i nā lāʻau ʻē aʻe e kōkua e mālama i kēia hopena. Ke kono aku nei au e kamaʻilio pū me kāu kauka e pili ana i ka hoʻokaʻawale i ke ʻano lāʻau me nā mea ʻona paʻakikī.

Alexandra Matveeva, 45 makahiki, St.

Hoʻopiʻi me ka hypertension ma hope o ka hoʻomaʻa ʻana o ka thyroid. Ua kuhikuhi ka kolohe iā MikardisPlus i nā papa o ka hana lōʻihi. Makemake wau i ka lāʻau lapaʻau, hoʻohaʻahaʻa iki i ke koko. ʻAʻole hopena ka hopena o ka lāʻau i ke kino a ʻaʻole e hoʻonāukiuki i ka hopena, anaphylactic ʻano. Ua hōʻea ka paʻu i 130/80 a noho i kēia pae. Ke kuhikuhi aku nei wau iā ʻoe e hana i nā wā i hala o 2 mau wiki i ka wā e lawe ai i ka lāʻau lapaʻau.