Pehea e hoʻohana ai i ka lāʻau lapaʻau Cardiask?
ʻO CardiASK kahi hana antiplatelet hou e kālai ana i ke kaʻina hana o ke koko, ua loaʻa ka hopena anti-inflammatory, antipyretic a me analgesic.
ʻAno Latin: CardiASK.
Hoʻonui papa inoa: Acetylsalicylic acid.
Hana hana: Canonpharma, Rusia.
ʻO 1 papa o CardiASA ka mea he 50 a 100 mg o ka acetylsalicylic acid.
ʻO nā mea kōkua ua loaʻa i ka pauka palaoa, calcium stearate, lactose, castor oil, microcrystalline cellulose, ʻumikumamāwalu-80, plasdon K-90, plasdon S-630, talc, titanium dioxide, hōʻuluʻulu i ka MAE 100P, propylene glycol.
E hoʻokuʻu i ke ʻano
Loaʻa CardiASK i ka ʻaoʻao o nā papa enteric-coated. Aia nā papa keʻokeʻo i kahi pōʻai, pānaʻi biconvex me kahi ʻono a maikaʻi hoʻi (hoʻonaninani ʻia ke ʻano)
Loaʻa nā papa i nā ʻāpana he 10 i loko o nā paena blister. Hoʻopili ʻia nā pēpē piha i nā pepa kāleka o 1, 2, 3 mau ʻāpana.
Pharmacokinetics a me ka lāʻau lapaʻau
ʻO CardiASK kahi mea hoʻohui antiplatelet a me NSAIDs. ʻO ka hana nui o kēia lāʻau lapaʻau ka irisversible inactivation o ka cyclooxygenase enzyme. A hopena, aia kahi palaka o ka synthesis o ka thromboxane A2 me ka kaʻe ʻana o ka hoʻohui platelet. Ua loaʻa iā CardiASK ka hopena antipyretic, anti-inflammatory a me ka analgesic hopena.
Hoʻohanaʻia ka hoʻohuihui o ka acetylsalicylic acid ma ka ʻaoʻao o luna o ka mea liʻiliʻi. Loaʻa ka ʻike kiʻekiʻe o kahi mea i loko o ke koko i nā hola 3 ma hope o ka lawe ʻana i ka lāʻau. Hiki i ka acetylsalicylic acid ke hoʻokaʻawale i nā huapalapala i loko o ke ate, ma laila e hana ai i nā metabolites me kahi haʻahaʻa haʻahaʻa haʻahaʻa. Hoʻopili ʻia ka mea hana ma o ke ʻano o ka urinary i loli a me ke ʻano o ka metabolites. ʻO ka hapalua hapalua o nā mea ikaika i loli ʻole he 15 mau minuke, metabolites - 3 hola.
Ua kuhikuhi ʻia ʻo CardiASK i kēlā mau ʻano:
- me ka angina pectoris,
- me ka hoʻohālikelike o ka infarction myocardial akene, ka mea nui loa i nā poʻe maʻi me ka maʻi mellitus, ʻemō, hypertension a i ʻole hyperlipidemia,
- me ke kākā ʻana o ka ischemic stroke,
- no ka pale ʻana i ka thromboembolism ma hope o ka ʻoihana a i ʻole nā loina invasive,
- me ka prophylactic e pale ai i nā ulia cerebrovascular,
- no ka pale ʻana i ka hohonu o ka maʻi trombosis,
- me ka prophylactic e pale ai i ka embolism pulmonary a me kāna mau lālā.
Nā Hoʻohui
Ua hoʻohālikelike ʻia ʻo CardiASK:
- me ka wī o ka gastrointestinal tract,
- i ka hiki ana mai o ka haukē.
- me ka kaʻe ʻana o ke kaʻehele ʻana,
- inā loaʻa nā pilikia me nā keiki,
- i ka wā lact,
- i I a me II trimester o ka hāpai ʻana,
- malalo o 18 makahiki,
- me ka "aspirin triad" (Fernand-Vidal triad),
- i ke kino o ka mōʻaukala a me ka kō ʻole o ka hana,
- me ka diathesis hemorrhagic,
- inā e lawe aku i ka methotrexate i kahi pane ma mua o 15 mg i hoʻokahi pule,
- i ka heleʻana o ka hypersensitivity i nā mea hana koʻikoʻi a me nā mea kōkua o ka lāʻau.
Ua kuhikuhi ʻia ʻo CardiAAS me ka mālama ʻana i nā poʻe maʻi me ka gout, ka hyperuricemia, nā ʻeha a me ke kahe ʻana o ka ʻōpū o ke kūwili ʻana, a me nā maʻi o ke ʻano o ka pau ʻana o ke ʻano maʻi. Hoʻohana ʻia ka CardiAAS me ka mālama aka i nā poʻe me ka hemo ʻoi, polyposis o ka mucosa nasal a me ka koina o K K.
Ke ʻano o ka noi
Ke hōʻike ʻia nei ka CardiASK e lawe ʻia ma mua o ka papaʻaina. Pono e holoi ʻia nā papa ʻōlelo waha me ka nui o ka wai. ʻO ka ʻae i ka lāʻau CardiASK e hāʻawi i kahi noho kapu hoʻokahi. Akā ma ka maʻamau hoʻokahi ka pālākiō no ka pākeke he 150 mg - 2 g, a me kahi lā maʻamau o 150 mg he 8 g.
Lawe nā keiki ma lalo o ka 18 mau makahiki i ka CardiASK ma ka hapa o 10-15 mg no 1 kilograma o ke kaumaha o ke keiki. Hoʻomaopopo ʻia e hoʻokaʻawale i kēlā me kēia lā i 5 mau pona.
ʻO 100 mg o ka lāʻau ke kauoha ʻia no myocardial infarction i ka manawa o ka hoʻopā, a me ke ʻano o ka pale ʻana o nā hihia loea cerebrovascular a me ka hahau.
Pono ka papa kauka hoʻohālikelike kikoʻī e ke kauka. Kuhi ʻia ʻo CardiASK no ka hoʻohana ʻana i ka lōʻihi.
Pākuʻi a me nā ʻōlelo hoʻi
Hiki i CardiASK ke hōʻeha i ka neʻe a me ka bronchospasm. ʻO ka momona, ka hopena kūlohelohe, polyposis o ka mucosa nasal a me nā maʻi hanu maʻi hiki ke lilo i kahi pōpilikia kūikawā.
Hiki i CardiASK ke hōʻeha i nā huhū ākea i ka manawa a ma hope o ka ʻoihana. ʻO ka hui pūʻana o ka CardiASA me nā lāʻau thrombotic, anticoagulant a me nā lāʻau antiplatelet e hoʻonui i ka hopena o ke kahe.
Inā makemake ka mea maʻi i ka gout, a laila CardiASK i nā hoʻohaʻahaʻa i hoʻohaʻahaʻa i ka hoʻomohala ʻana i kēia maʻi.
Hiki i nā dosis o CardiASA ke kumu i ka hopena hypoglycemic, pono e noʻonoʻo ʻia kēia hiʻohiʻona no nā mea maʻi e maʻi nei i ka maʻi maʻi.
ʻAʻole ia e hāʻawi i hoʻohui i CardiASK i nā ibuprofen.
ʻO ka CardiASK i nā haʻahaʻa kiʻekiʻe hiki ke hoʻowalewale i ke koko i ka hoʻowalewale ʻana.
ʻAe ʻokola, i lawe pū ʻia me ka lāʻau lapaʻau, hiki ke hōʻino i ka mucosa gastric a hoʻolōʻihi i ka manawa koko.
Nā hopena hopena
Wahi a nā noiʻi a me nā ʻōlelo mai nā mea kūʻai aku, hiki paha i CardiASK ke hōʻike i nā hopena like ʻole:
- hoʻohuka, puuwai, nausea, ʻeha ʻeha, gastrointestinal ulcer, gastrointestinal koko, hoʻonui i ka hana o nā transaminases hepatic,
- Hōʻoiaʻiʻo bronchospasm
- kaluha a kalaiwa,
- nahuahua laula, ma nā hihia ano luhi, ua nānā ʻia ka anemia,
- ʻO ka edema o Quincke, urticaria a me nā ʻano anaphylactic ʻano,
I nā hōʻailona mua o nā hopena ʻaoʻao, pono e hoʻopau i ka lāʻau a ʻimi i nā ʻōlelo lapaʻau.
Ke keu
Hōʻike ʻia ka hailona o ka overdose ma ka nausea a ka luaʻi, ka dizziness, tinnitus, ka lohe ʻana a me ka hilahila. Ua hōʻike ʻia kahi overdose e like me ke koma, ka hanu a me ke aloha cardiovascular, ka maʻi, ka maʻi ketoacidosis, ka hoʻopihapiha, ka alkalosis a me ka hypoglycemia. ʻO ka ʻōpoi weliweli loa no ka poʻeʻelemakule.
ʻO ka pae kiʻekiʻe o ka overdose e hoʻopau i ka hōʻemi ʻemi. Pono ka overdose maʻi i ka hoʻokipa, gastage lavage, ka hoʻohālikelike o ka kaulike kumu-kūloko, ka waikawa alkaline diuresis, hemodialysis a me ka hoʻouluʻana i ka infusion. Hāʻawi ʻia kekahi e hāʻawi i ka mea i hoʻopulapula i ka hiona a hoʻomō i ke ʻano maʻi.
Ka kuʻikahi me nā lāʻau lapaʻau ʻē aʻe
Hoʻonui ka CardiASK i ka hopena therapeutic o ka methotrexate, thrombolytics, antiplatelet agents, nā ʻōpū hypoglycemic, digoxin, heparin, kūlohelohe anticoagulants, waikawa valproic.
Hiki i nā pilikia hōʻalo mai ka hematopoiesis ke hoʻoulu ʻia e ka hui pū ʻana o CardiASK me nā anticoagulants, thrombolytics, methotrexate a me nā mea hana antiplatelet.
ʻO ka CardiASK palupalu i ka hopena therapeutic o nā lāʻau uricosuric: ʻāpono ACE, benzbromarone, diuretics.
Lapaʻau lāʻau
ʻO ka hoʻokūkū o ka hana antiplatelet o ka acetylsalicylic acid (ASA) ʻo ia ka hoʻololi iki ʻana o ka cyclooxygenase (COX-1). Ke alakaʻi nei kēia i ka pani ʻana o ka platelet aggregation a me ka pale ʻana i ka thromboxane A synthesis.2. ^ E Ha yM. ʻO ka hopena antiplatelet e hōʻike nui i ka hopena ma nā platelets, ka mea e nalo nei i ka hiki ke hana hou i synthesize cyclooxygenase. ʻO ka lōʻihi o ka hopena antiplatelet ma kahi o 7 mau lā ma hope o hoʻokahi pākahi, a ʻoi aku ka ʻōlelo i nā maʻi kāne kāne ma mua o nā wahine.
Hoʻonui ka ASA i ka hana fibrinolytic o ke koko koko a hōʻemi i nā kikoʻī o nā huaʻala coagulation depend-bit K (X, IX, VII, II).
Nā ʻōkuhi no ka hoʻohana ʻana iā Cardiasca
Hoʻohana ʻia ka lāʻau lapaʻau ma mua o ka papaʻaina. Pono e holoi ʻia nā papa i ka wai nui.
Ke kuhikuhi nei i nā ʻōkuhi no ka hoʻohana ʻana iā Cardiask i kahi ka hoʻoponopono regimen kanaka hoʻokahi:
- no nā pākeke, hoʻokahi pāmeʻai hiki mai 150 mg i 2 g, a me nā kaha i kēlā me kēia lā, i ka huli ʻana, mai 150 mg a 8 g. Ua lawe ʻia ka lāʻau lapaʻau i 2-6 mau manawa i ka lā.
- no nā keiki, hoʻokahi ka pākēnē he 10-15 mg pākeke. Lawe ʻia nā pilleʻa i 5 mau manawa i ka lā,
- eiai myocardial infarctiona me ka no ke kumu pale māhāa Kāpilikia serebrovascular E kaukaʻi i ka 100 mg o ka lāʻau i ka lā.
Pono ka ʻae ʻana a me ka pauku dosage a pau me ka kauka. Ke kuhikuhi nei i ka hoʻohana ʻana i kā Cardiasca e hōʻike ʻia ana ka lāʻau lapaʻau no ka hoʻohana wā lōʻihi. Hoʻoholo ʻia ka lōʻihi o ke papa e ka kauka.
Hoʻohui
Hoʻonui kēia lāʻau lāʻau i ka hana o kēia mau lāʻau lapaʻau:
Hiki ke hopena paha nā hopena mai nā hemopoietic kino me ka hui pū ʻana me Cardiaska me Methotrexate, anticoagulants, nā ʻaihini antiplatelet, thrombolytics.
Hōʻemi ka lāʻau i ka hopena o uricosuric lāʻau lapaʻau: Benzbromarone, Diuretics, ACE paleai.
ʻO ka lā kau
ʻO 2 mau makahiki kahi ola.
Eia nā ʻōlelo hoʻohālikelike o Cardiask:
Loaʻa nā loiloi ma ka lāʻau lapaʻau Cardiask he nui loa. Ma nā kolamu, manaʻo nui ka poʻe inā ʻoi aku ka maikaʻi o kēia hāmeʻa ma mua o kāna nā kikowaena. ʻAʻohe pane iki i kēia nīnau, no ka mea, aia ka nui o nā lāʻau like ʻole a he mana āpau lākou a pau.
He kūpono pū ka manaʻo o nā loea e pili ana i ka Cardiasca. Hōʻike pinepine lākou i kēia no ka pale ʻana myocardial infarction, māhāa ʻōpalaola eīologies kūʻai.
Nā hōʻailona no ka hoʻohana ʻana
Hoʻohana ʻia ia no ka pale ʻana:
- kaʻeha myocardial infarction i mua o nā mea kūpono e like me ka hypertension arterial, diabetes mellitus, hyperlipidemia, ʻelemakule, ulaula a me ka luhi.
- myocardial infarction,
- halihali neʻe i waena o ka lolo,
- maʻi puhipuhila a me ka embolism pulmonary,
- thromboembolism ma hope o invasive a me surgical interventive ma luna o ke koko,
- he poho.
Eia kekahi, ʻoi aku ka hoʻohana ʻana no ka angina unstable.
Nā ʻōkuhi no ka hoʻohana ʻana iā Cardiask (ke ʻano a me ka anaana)
Lawe ʻia nā papa ma mua o ka papaʻaina. Pono ka lāʻau lapaʻau no ka hoʻohana pono ʻana, ʻo ka lōʻihi ka mea i hoʻoholo ʻia e ke kauka.
- ʻO ka pale mua a me ka maʻi myocardial infarction ma mua o nā mea pōpilikia: 50-100 mg / lā. Kāohi i ka hoʻihoʻi pinepine i ka infarction myocardial, paʻa a me ka paʻa ʻole: 50-100 mg / lā.
- Angina hiki ʻole (me ka hoʻomohala hoʻomohala ʻana i ka lāʻau myocardial infarction): 50-100 mg / lā.
- ʻO ka paleʻana i ka thromboembolism ma hope o ka hana a me ka hoʻouluʻana vascular invasive: 50-100 mg / lā.
- Kāohi i ka wē ischemic a me ka ulia cerebrovascular transient: 50-100 mg / lā, thrombosis vein hohonu a me ka embolism pulmonary a me kāna mau lālā: 50-100 mg / lā.
Nā hopena hopena
ʻO ka lawe ʻana iā Cardiask e lilo i lalo nā hopena ʻaoʻao:
- Mai ka pūnaehana ʻana: ka huhū, ka lua, ka ʻōpū, ka ʻeha o ka ʻōpū, ka puʻu ʻana o ka gastrointestinal, nā ʻōpū o ka membrane o ka duodenum a me ka ʻōpū, hoʻonui i ka hana o nā transaminases hepatic.
- Mai ka pūnaehana kaomi: ka piʻi nui ʻana o ke koko, i nā hihia neʻe - anemia.
- Mai ka papa hana hanu: bronchospasm.
- Mai ka ʻaoʻao o ka kaena i loko o ka lahui: tinnitus, hina, ʻeha.
- Nā ʻano maʻi: Ka edema o Quincke, urticaria a me nā hopena anaphylactic.
Ka hana lāʻau lapaʻau
Ua loaʻa he Cardiask i ka hopena antiplatelet, kahi i kau ʻia ma ka hoʻohui ʻole ʻana o COX-1, ke kāohi nei i ka paʻi o ka thromboxane A2 a me ka pale ʻana i ka platelet aggregation. He mau ʻano hana ʻē aʻe o Cardiask no ka hoʻopaʻa ʻana i ke kīpē o platelet, e hana pono ai ia i nā ʻano maʻi like ʻole. I nā dosis kiʻekiʻe, ua loaʻa kēia lāʻau i kahi analgesic, anti-inflammatory a me ka antipyretic hopena ma ke kino.
Nā ʻōlelo kikoʻī
- Hiki ke hoʻonāukiuki i ka hoʻomohala ʻana o ka bronchospasm a i ʻole ka hoʻonui ʻana i ka hoʻohuihui bronchial. I ka hoʻonui ʻia aʻe o ka hopena o ka hana ʻino i ka mōʻaukala o ka hehiki, ka polyposis nasal, nā maʻi ʻeha o ka maʻi a me kahi maʻi maʻi.
- Ke hoʻomau nei ka hopena o ka ASA ma ka platelet aggregation i mau lā ma hope o ke alakaʻi ʻana. Hoʻonui kēia i ka pilikia o ke kahe koko i ka wā o ka hōʻola paha a i ka wā postoperative. Inā pono e hoʻopau loa i ke koko, pono pono e haʻalele loa i ka hoʻohana o ka lāʻau.
- Ma nā wai haʻahaʻa, hiki iā ia ke hoʻonāukiuki i ka hoʻomohala ʻana i ka gout i nā poʻe i hōʻemi i ka uric acid excretion.
- I nā hopena kiʻekiʻe, he hopena hypoglycemic, kahi mea nui e noʻonoʻo pono ai i ke koho ʻana i nā poʻe maʻi me ka maʻi mellitus e loaʻa ana i nā lāʻau hypoglycemic.
- Me ka hui pū ʻana o nā lāʻau lapaʻau a me nā salicylates, pono e hoʻomanaʻo ʻia i ka wā o ka mālama ʻana i ka hoʻokaʻina o nā mea o ka hopena i loko o ke koko, e hoʻemi ʻia, a ma hope o ka overdose, hiki i kahi overdose o salicylates.
- Ke puka nei i ka nui o ka hopena o ka acetylsalicylic acid me ka hopena o ke koko gastrointestinal.
Hoʻohui nūhou
- Me ka hoʻohana pū ʻana o nā lāʻau lapaʻau a me ka methotrexate, hoʻonui ka acetylsalicylic acid i ka hopena o ka hopena ma muli o ka hoʻēmi ʻana o ka hoʻomaʻamaʻa ʻana i ka hana a me ka haʻalele ʻana mai nā mea paʻa me nā protein plasma.
- Hoʻonui i ka hopena o nā anticoagulants kūlike a me ka heparin ma muli o ka hana platelet impaired a me ka weheʻana i nā anticoagulants kūlohelohe mai nā mea pili i nā protein plasma.
- Ke hui pū nei, hoʻonui i ka pono o nā lāʻau antiplatelet a me nā thrombolytic.
- Ma muli o ka hopena hypoglycemic acetylsalicylic acid, ʻo ka hoʻohana ʻana i ka lāʻau lapaʻau i nā kiʻekiʻe kiʻekiʻe e hoʻomaikaʻi i ka hana o ka insulin a me nā derivatives sulfonylurea.
- Hoʻonui i nā hopena o ka digoxin, e hoʻonui ana i kona kao i loko o ka plasma. Hoʻonui hou ia i ka hana o ka waila valproic, hoʻoneʻe iā ia i nā pilina me nā protein plasma.
- Me ka hoʻohana pū ʻana o nā lāʻau lapaʻau a me nā lāʻau uricosuric, hōʻemi ka hopena acetylsalicylic i ko lākou hopena ma muli o ka hoopau ʻana o ka waika uric.
- Ke hui pū ʻia me ka ethanol, nānā ʻia kahi hopena hoʻohui.
He kumukūʻai ma nā hale kūʻai
ʻO ke kumu kūʻai o Cardiask no 1 mau pahu hoʻomaka mai 45 rubles.
ʻO ka ho'ākāka ʻana ma kēia ʻaoʻao he kope maʻalahi o ka mana o ka hanana o ka lāʻau lapaʻau. Hāʻawi ʻia ka ʻikepili no ka ʻike pili wale nō ʻaʻole ia he kumu no ka hōʻike pilikino. Ma mua o ka hoʻohana ʻana i ka lāʻau lapaʻau, pono ʻoe e kamaʻilio i kahi loea a hoʻomaʻamaʻa iā ʻoe iho me nā ʻōlelo i ʻae ʻia e ka mea hana.
Nā ʻōkuhi no ka hoʻohana ʻana i CardiASK: kaʻina a me ka ʻihi
Pono e lawe ʻia ka CardiASK ma mua o ka papaʻaina, me ka nui o nā ʻano wai.
- ʻO ka pale ʻana i ka infarction myocardial akala: 100-200 mg i kēlā me kēia lā a ʻo 300 mg i kēlā me kēia lā ʻē aʻe (ʻoi ʻia ka pipiʻi i ka papa mua i kipi koke ʻia).
- ʻO ka mālamaʻana i ka infococose myocardial akala i mua o nāʻike i nā pilikia: 100 mg i kēlā me kēia lā a 300 mg i kekahi mau lā aʻe,
- ʻO ka pectoris angina hiki ʻole, me ka pale ʻana o ka hoʻoulu iʻe myocardial infarction, stroke, transient cerebrovascular accident, thromboembolic komplitions ma hope o nā hoʻokolohua invasive a i ʻole ka maʻi vascular: 100-300 mg i kēlā me kēia lā,
- Kāohi i ka thrombosis vein hohonu, thromboembolism o ka pulmonary artery me kāna mau lālā: 100-200 mg i kēlā me kēia lā a 300 mg o kēlā me kēia lā.
Hoʻoholo ka lōʻihi o ka lāʻau maʻi, akā ua hoʻohana ʻia ʻo CardiASK no ka manawa lōʻihi.
ʻŌpū a me ka lactation
ʻO ka lawe ʻana i ka CardiASA i nā papa kiʻekiʻe ma ka trimester mua o ka hāpai ʻana i hoʻonui ʻia ka hopena o ka hoʻolālā ʻana i nā ʻōpū ma ka pūpū (pale naʻau, ka wehe ʻana i ka palā o luna), no laila, ke kuhi ʻia ʻana o kāna kumu i kēia wā. Ma ka lua o ka hapalua o ka hapai ʻana, e ʻōlelo ʻia ana nā salicylates wale nō ma hope o ka hoʻomaʻamaʻa ʻana o nā pōmaikaʻi o nā pōmaikaʻi no ka makuahine a me ka hiki ʻana paha i ka ʻoihana, ma ka nui o nā lā o kēlā me kēia lā ʻaʻole nui aku i ka 150 mg a no ka manawa pōkole.
Ma ke kolu o ka wā helu o ka hapai ʻana, ʻo CardiASC i nā koina kiʻekiʻe (ʻoi aku ka 300 mg i kēlā me kēia lā) hiki ke hoʻonui i ka huhū ma ka makuahine a me ka ʻōpio, ka hana mua ʻana o ka papa arterial i loko o ka pūpū, pale ʻana o ka hana, a lawe koke i ka lāʻau i mua o ka hānau mau ke alakaʻi ʻana i ka hemorrhage intracranial. keiki. No laila, pāpā ʻia ka hoʻohana ʻana i ka lāʻau i kēia manawa.
ʻO ka ASA a me nā metabolites i loko o nāʻoihana liʻiliʻi i hele i ka waiū umauma. ʻO ka hoʻokaʻawale kūlea o ka lāʻau i ka wā o ka hoʻoulu ʻana, ʻaʻole ia he kumu e hoʻonāukiuki ai i ka pēpē a ʻaʻole pono e wehe i nā hānai. Eia nō naʻe, me ka hoʻomohala lōʻihi ʻana a i ʻole nā koina kiʻekiʻe o CardiASA, pono e hoʻokaʻawale i ka lactation.
Hoike e pili ana i ka CardiASK
Wahi a nā loiloi, kūpono kēlā ʻo CardiASK a loaʻa kahi hopena therapeutic i haʻi ʻia. Eia naʻe, hiki ʻole ke hoʻohālikelike i ka hopena o ka lāʻau lapaʻau a me nā mea kikowaena. Eia kekahi, ʻo nā mea maʻi e like me kāna uku haʻahaʻa.
E ʻōlelo maikaʻi nā poʻe loea e pili ana i ka lāʻau lapaʻau. Hoʻomaʻamaʻa pinepine ʻia ʻo CardiASK no ka pale ʻana i ka thrombosis o nā ʻano etiologies, nā maʻi a me nā infarction myocardial.