ʻO ke ho'āʻo ʻana no ka hemoglobin glycated: ke kumu maʻamau i nā kāne a me nā wahine me ka maʻi maʻi
Ua paʻi ka nūpepa olakino Pelekane i nā hopena o kahi hoʻokolohua i manaʻo ʻia e hoʻokūpaʻa i ka hilinaʻi o ka hemoglobin glycosylated a me ka hopena o ka make ma ka male kāne o ka hapalua kāne. Mālama ʻia ʻo HbA1C i ka poʻe manawaleʻa o nā makahiki like ʻole: mai 45 a 79 mau makahiki. Basically, he poe olakino (ʻaʻohe o ka maʻi maʻi).
I waena o nā kāne me ka heluhelu heluhelu o ka glucose a hiki i ka 5% (hana maoli ke kumu maʻamau), he make iki ka make (ma ka hapanui mai ka hōʻeha ʻana i nā puʻuwai a me nā hōʻeha). ʻO ka hoʻonui ʻana i kēia hōʻailona e ka neʻe ʻana o ka 1% ka hoʻonui i ka hiki i ka make ma ka 28%! Wahi a nā hopena o ka hōʻike, hōʻike ka HbA1C i ka nui o ka 7% i ka piʻi o ka make e 63% (i ka hoʻohālikelike ʻia me nā ʻano maʻamau), a ʻo 7% no ka mea maʻi maʻi mau ke manaʻo mau ʻia he hopena kūpono loa!
ʻO ka hoʻāʻo ʻana no ka hemoglobin glycated he ʻano nui ia, kahi ʻano ʻai ʻole biochemical e hiki ai iā ʻoe ke hoʻohālikelike pono i ka maʻi diabetes. Kōkua ia i ka nānā ʻana i ka pono o kāna mālama ʻana.
ʻO ka hana nui o ka hemoglobin ka lawe ʻana o ke oxygen i nā pū. Hoʻoikaika ka ʻōmaʻomaʻo me nā molekala glucose. ʻO kēia mau mea i kapa ʻia he glycosylated hemoglobin. ʻOi aku ka nui o nā koikoi i ke kahe koko, ua hoʻokumu ʻia ka hemoglobin glycated, kahi mea e loaʻa ai ke kiʻekiʻe o ka maʻi o ka maʻi maʻi a me kona mau hopena.
I kēia manawa, kauoha kēia hōʻike no ka hyperglycemia, hiki iā ia ke hōʻoia i ka maʻi diabetes i ka wā ʻaʻole i hoʻoponopono pono nā ʻano ʻē aʻe. Kōkua ka loiloi ʻike maopopo i ka maʻi diabetes i nā papa mua. E kōkua kēia hōʻike i ka maʻi maʻi maʻi e hoʻomaopopo i ka hoʻopololei ʻana i ka maʻi glycemia no 90-100 mau lā, pehea ka wikiwiki o ka maʻi diabetes, a inā paha e maikaʻi pono nā lāʻau hoʻoliʻi i koho ʻia.
ʻO ka hoʻopiʻi a me ka ʻoluʻolu o ka ʻōnaehana
Hoʻololi nā molekula kūleʻa i ke kahawai me nā ʻāpana koko ʻulaʻula. ʻO ka hopena ke hoʻopiʻi kūlohelohe ʻole e wāwahi ʻole a he make kēia mau ʻōmua i ka pauku. ʻO kēia mau waiwai o lākou e hiki ai i kahi manawa ke nānā i kahi pilikia ma mua koke iho, i ka wā ʻaʻole i manaʻo ka ʻike maʻamau i nā loli i ke koko.
ʻO ka nānā ʻana ma mua o ka papaʻaina e hiki ai iā ʻoe ke hoʻoholo i ke kōloli pōloli, ma hope o ka ʻai ʻana - e hāʻawi i kahi loiloi o kona kūlana ma lalo o ka ukana. ʻO ka glycated hemoglobin i ka mellitus o ka maʻi mellitus i manaʻoʻo ka glycemia i nā mahina ʻekolu i hala. He aha ka pono o kēia kaʻina loiloi?
- Hiki ke hoʻokō ʻia nei nā hoʻokolohua ʻaʻole wale i ke kakahiaka, ma ka palena o kahi mea make pololi, hōʻike ka hōʻike i ke kiʻi kūpono loa, e hōʻike ana i ka maʻi maʻi ma ke ʻano o ka prediabetes.
Hoʻoikaika preanalytical - koko i lawe ʻia ma waho o ka ʻoihana ke hoʻomau a hiki i ka hoʻāʻo ʻana i ka vitro.- Kōkua ka HbA1C e loiloi i ke kiʻekiʻe o ka hoʻopaʻi gula i loko o kahi maʻi maʻi, i mea e koho ai i ka ʻai kūpono no nā lāʻau lapaʻau hypoglycemic.
- ʻAʻole paʻa i ka mea kuhikuhi i ka minamina, nā maʻi, nā hewa i ka meaʻai, ka lawe ʻana i kekahi lāʻau lapaʻau.
- ʻOi aku ka wikiwiki o ka hōʻike hoʻokolohua, ʻoi aku ka maikaʻi a me ka maʻalahi ma mua o kahi hōʻike hoʻoneʻeneʻo glucose maʻamau, kahi e hana ai i 2 mau hola.
Hoʻoikaika preanalytical - koko i lawe ʻia ma waho o ka ʻoihana ke hoʻomau a hiki i ka hoʻāʻo ʻana i ka vitro.Me ka anemia, hemoglobinopathy a i ʻole pilikia me ka thyroid gland, a me ka nui o ka nui o ke kō o ka meaʻai i nā momona a me nā huaora E a me nā hopena, ʻaʻole pololei nā hopena. ʻAʻole kūpono ia ke ʻano no ka hoʻokolokolo ʻana i ka maʻi hyperglycemia.
Ka hoʻāʻo ʻana no ka wahine hāpai wahine. Hiki ke ʻike ʻia kahi kiʻi pahuhopu wale ma ka mahina 8-9, ʻoiai ʻo nā pilikia e hele mai ke kua ma ka lua o ka moku. Aia ka poʻe maʻi me ka hoʻohaʻahaʻa ʻia ma waena o HbA1C a me ka heluhelu heluhelu pālua.
Loaʻa i nā hemahema ka uku o ka hoʻokolohua: ʻo ke kumukūʻai kumukūʻai no nā lawelawe he 520 rubles a ʻoi aku ʻo 170 mau rubles ka uku no ka sampling koko venous. ʻAʻole loaʻa nā wahi āpau i hoʻokolohua.
No ke aha hoʻi e hōʻike ai i kahi hoʻokolohua?
ʻO Hemoglobin kahi protein e loaʻa ai ka hao a he hiki iā ia ke lawe i ka oxygen i loko o ke kino. Noho wale nā ʻāpana koko ʻokoʻa o ke kino i nā mahina 3-4 wale nō, i ʻole ka hana pono e lawe i ka hōʻike ʻo HbA1C me kēia mau hiʻi.
Hāʻawi kahi lōkoki i nā lihue-enzymatic i kahi paʻa paʻa o ka glucose a me ka hemoglobin. Ma hope o ka glycation, hoʻokumu ʻia i ka hemoglobin glycosylated. Kuhi ka ulu ʻana o nā hopena ma ka heluhelu ʻana o ka mika ma ka manawa kau. Hiki i ka HbA1C ke nānā i ka hoʻohui ʻana o ke koko i nā lā 90-100.
Ma mua o kahi hoʻokolohua maʻamau, nui nā maʻi maʻi "hoʻomau i ka noʻonoʻo," e ho'āʻo nei e hoʻomaikaʻi i ke kiʻi o nā hōʻike. Ke hōʻike nei no ka HbA1c, ʻaʻole e holo ka hoʻopunipuni nei, e hōʻike pono ʻia nā hemahema a pau i kaʻai a me ka lāʻau.
ʻO nā hiʻohiʻona o ka loea maʻalahi e pili ana i ka wikiō a kau ʻia e ka ʻōlelo a Profesor E. Malysheva:
Nā Kūlana HbA1c
Ke ʻole o nā hōʻailona o ka maʻi maʻi, ua hoʻohālikelike nā kumu o HbA1C ma ka waihona o ka 4-6%. Hoʻohālikelike lākou i ka hoʻohālikelike ʻana me ka huina o nā ʻāpana koko ʻulaʻula i ke kahe koko. Hōʻike kēia kuhikuhi i kahi metabolism yang kahi momona maikaʻi loa.
Loaʻa ka hiki ʻana mai o ka maʻi "momona" me nā helu HbA1C mai 6.5 a 6.9%. Inā lanakila lākou i ka paepae o 7%, ʻo ia ka hopena o ka metabolism o ka lipid, a ua hoʻololi ka holi i ka prediabetes. ʻO nā palena o ka hemoglobin glycated (ke kumu maʻamau i ka mellitus maʻi diabetes) ʻokoʻa i nā ʻano maʻi like ʻole a me nā ʻano ʻokoʻa. Hōʻike maoli ʻia kēia mau ʻokoʻa i ka papaʻaina.
He mea hoʻomaopopo i nā poʻe ʻōpio e mālama i ko lākou HbA1C haʻahaʻa ma mua o ka maʻi maʻi o ka pākeke. ʻO ka nānāʻana i ka hemoglobin glycated no nā wahine hāpai he mea kūpono wale no 1-3 mau mahina, i ka wā e hiki mai ana, ʻaʻole i hāʻawi i nā loli hormonal ke kiʻi kūpono.
HbA1C a me ka hemoglobin momona
Palapala hemoglobin Fatal i loko o nā keiki hou. ʻAʻole e like me nā analogue, ʻoi aku ka hana o ka molowa aku i ka oxygen i nā pū. He hopena anei ka hemoglobin momona?
Hoʻopili ke kiʻekiʻe o ka oxygen hāmeʻe i loko o ke kahe i ka ʻōnaehana o ka mea hoʻōlaʻai, a hoʻololi ʻia ka nui o nā hāmeʻe i ka glucose i hana hou ʻia me ka loli glycemia. Hoʻopilikia kēia i ka hana o ka pancreas, ka hana insulin a me ka hemoglobin glycated no ka maʻi diabetes.
Nā kikoʻī o ka hoʻāʻo ʻana no ka hemoglobin glycated - i ke wikiō:
Nā hiʻohiʻona o ka aʻo ʻana
ʻO kahi pōmaikaʻi nui o ka hoʻokolokolo ʻana no ka hemoglobin glycosylated ʻo ka nele o ka pono o kahi hoʻomākaukau ʻana a me ka hiki ke alakaʻi iā ia i kahi manawa kūpono. Ke hiki ke loaʻa i nā ʻoihana kūikawā ke kiʻi i ke kiʻi kūpono ʻole e pili ana i ka inu ʻana i ka meaʻai a me ka lāʻau lapaʻau, nā maʻi puʻuwai, nā ʻano kaumaha, a i ʻole ka waiʻona.
No ke kiʻi ʻoi aku ka pololei o nā hopena, e hāmama ʻia e haʻalele i ka ʻaina kakahiaka, no ka mea, ua hoʻomanawanui ka mea maʻi, e like me ke kānāwai, a pili paha kēia i kekahi mau hoʻokolohua. I kahi lā a ʻelua paha āu e ʻike ai i ka hopena. I ka kūkākūkā ʻana me ka endocrinologist, pono ʻoe e hoʻomaopopo iā ia e pili ana i kāu anemia, maʻi maʻi pancreatic, a me ka hoʻohana ʻana o nā huaora.
Lalo paha nā hopena hōʻike i ka wā e koho ai i nā mea hana like ʻole. Aia ia i nā ala i hoʻohana ʻia ma ka ʻoihana lapaʻau. E hoʻopaʻa i ka dinamics o ka hoʻomohala ʻana o ka maʻi, pono ʻia e hoʻokau hoʻomaʻamaʻa i kēlā me kēia wahi. He mea nui ia e hoʻomaʻamaʻa pinepine i ka hoʻāʻo ʻana: ua loaʻa iā ia i loko o kahi maʻi i hōʻemi ʻia ka HbA1 o ka 1% kūwaho e hōʻemi i ka hopena o nā hoʻopiʻi.
| ʻ oflelo LED | ʻO nā ʻōhua hiki | Hemi hoemi,% | ||||||||||||||||||||||||||||||||||||
| ʻAno maʻi type 1 | Retinopathy ʻĀnapana | 30 25-40 | ||||||||||||||||||||||||||||||||||||
| ʻAno maʻi type 2 | Nā Micro a me nā macroangiopathy Make mai ka maʻi diabetes ʻO ka make kino | 32Hoʻopilikia ʻia ka HbA1?ʻO ka palena o ka HbA1 ma lalo o ka maʻi maʻamau i ka maʻi diabetes e pili ana i ka hypoglycemia. Hoʻomaʻamaʻa iki kēia hopena ma mua o ka hoʻonuiʻana i ke ʻano. Me ka niho momona, me ka hana mau ʻana i nā sweets, ka hana ʻana no ka pancreas no ka hoʻohana ʻana, e hana ana i ka nui o ka hormone. ʻO nā mea pono no nā kuʻekuʻe neoplasms e hana ai nā b-cell i ka nui o ka insulin. ʻO ka hoʻohuiʻana i ka maʻi diabetes a me ka makemake culinary o ka niho momona, aia kekahi mau kumu no ka HbA1 haʻahaʻa.
I mea e ʻike ai i nā kumu kikoʻī e pili ana i ka pae o ka hemoglobin glycated i ka diabetes mellitus, pono ia e hoʻomaʻamaʻa piha.
Nā kumu i hoʻonāukiuki i ka hoʻonui ʻia o ka HbA1ʻO ka hoʻonui ʻana i ke ʻano o ka hemoglobin glycated i ke ʻano 1 a i ʻole ke ʻano lā 2 ʻano mea hiki ke ʻano he hyperglycemia. Hōʻike pinepine ʻia nā maʻi pancreatic i ka wā kākau a HbA1 ma mua o 7%. Hōʻike nā hōʻike o 6-7% i ka hoʻomanawanui o ka hoʻohaʻahaʻa glucose a me nā maʻi hoʻokūkū.
Hōʻike ʻia ka Hyperglycemia ʻaʻole me nā ʻano like ʻole o ka maʻi diabetes, akā pū kekahi me nā pathologies o ka nui o ka lāʻau thyroid, ka hōʻoki ʻana o ka ate, nā pilikia o ka hypothalamus (ʻo ka māhele o ka lolo i kuleana no ka hana o nā kuli endocrine). Inā hoʻāla nā keiki (mai ka 10%) hemoglobin glycated, pōʻino hiki ke kī maoli i lalo, e nalowale ana ke keiki i kahi ʻike a hiki i ka makapō. Inā ʻaʻole i hoʻoholo mua ka pilikia pono loa, hiki ke hoʻemi ia me ka lāʻau lapaʻau e 1% i kēlā me kēia makahiki.
ʻO ka kontrol Glycemic ma ka homeMe kekahi ʻano o ka maʻi maʻi, e nānā pono ʻia ke ʻano o kou koko i kēlā me kēia lā e hoʻoponopono i ka ukana, kaʻai ʻana a i ʻole ka lāʻau i nā mea lapaʻau inā pono. ʻO ka pinepine e nānā i ka mika mika no ka ʻaina wikiwiki, 2 mau hola ma hope o ka ʻaina kakahiaka, ma mua a ma hope o ka ʻaina a me ka pō. I ke ʻano maʻi diabetes type 2, inā ʻaʻole e loaʻa ka mea maʻi i nā inikini insulin, 2 ua lawa nā kaʻina hana. Hoʻoholo ʻia ka hoʻonui pinepine ʻia e kēlā me kēia maʻi e ke kauka. Kahu ʻia nā hopena o ka maʻi maʻi o ke anemia o ka glucometer i loko o kahi diary e nānā ai i ka ʻike ma nā dinamika. Hoʻomaopopo ʻia e nānā i ke kō i ka wā hāpai, i ka wā huakaʻi, me ka naʻau a i ʻole ka hana naʻau.
ʻAʻole ke kaohi nei kekahi mau maʻi maʻi glycemia i ka wehewehe ʻana i kā lākou hoʻoholo ʻana ma ka hopohopo ʻaʻole e hoʻopilikia maikaʻi ʻia nā ʻike. ʻO nā hopena o ka hōʻike hōʻike hiki ke hoʻomaopopo ʻia mai ka papa.
Pehea e mālama ai i kāu kola plasmaPono nā ʻōlelo paʻa e pono ai ka maʻi diabetes HbA1C ma lalo o 7%. ʻO kēia wale nō, hōʻemi piha ʻia ka maʻi diabetes, a heʻuʻuku ka hopena o nā hōʻeha. ʻO ka hapa, mālama ka haʻahaʻa haʻahaʻa-kalaka i kēia pilikia, akā ʻo ka pae o ka uku no ka maʻi diabetes e pili pono i ka hanana o ka kūlana hypoglycemic. ʻO ka mea i manaʻo ai ke kaupaona ma waena o nā hoʻoweliweli o ka hypoglycemia a me hyperglycemia, aʻo kahi maʻi maʻi maʻi i kona ola a pau. ʻO ka glycated hemoglobin o ka ʻikepili no 90-100 lā, a hiki ʻole ke hoʻēmi ma ka manawa pōkole, a pōʻino. ʻO ke kūlana nui no ka uku ʻana i ka glycemia a me ka pale ʻana i nā hoʻopiʻi i nā hōʻeha o ka metabolism, ʻo ia ka mālama paʻa ʻana i ka meaʻai.
Pono ka pīpīʻai ʻai, a hiki i 6 mau lā i ka lā. ʻO nā protein a me nā ʻowa e hoʻokaʻawale loa aku. ʻO ka wela wela o nā huahana - kaomi: kaū, ka palaoa, kaʻaila. Ke kāohi i ka paona, ʻona, ka maikaʻi a me ka, o ke kō, ka mea nui, he mea nui ia e hoʻomohala a hana i ka ea i ka ʻūhū hou i kāu iho o ke ʻano, e pili ana i ka makahiki a me ke ʻano o ke olakino. ʻO ka mālama mau ʻana i ka hemoglobin glycosylated i ka diabetes mellitus he mea pono no ka uku ʻoi loa o ka glycemic. Hōʻike hōʻike pololei i nā manawa pono ʻole e hoʻoponopono e hoʻoponopono i ka regimen lapaʻau, i mea e pale ai i nā hōʻeha hōʻeha o ka maʻi maʻi. Hoʻohui ʻia ka hōʻike ʻo HbA1 e ka Ahahui ʻEulopa o Endocrinologists i loko o ka paʻakikī o nā māka no ka loaʻa ʻana o ka maʻi maʻi. No ka ʻike hou aku e pili ana i ka palapala hōʻike no HbA1, e ʻike i ke wikiō:
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No nā wahine hāpai a me nā keiki, ʻo ka nānā ʻana i ka hemoglobin glycated ʻaʻole mea nui loa i nā mea kahiko. Inā mālama ʻole ʻoe i kēia mau loiloi, nā abnormalities i ka hoʻokumu ʻana o ka ʻōpio, hānau mua, a me ka hōʻalo ʻana o ka olakino wahine. ʻO ka hemoglobin haʻahaʻa ma kēia māhele he pilikia maʻamau, no ka mea, ʻoi aku ka nui o kā lākou hao hao (a hiki i ka 15 - 18 mg).
Inā pilikia ke maʻi maʻi a me ka holomua, ʻaʻole pono ʻoe e kaupalena i ka hōʻike ʻo HbA1C hoʻokahi. ʻAʻole ia i hōʻike i nā loli i ke kahe o ke koko me ka ukana kālaiā ʻana, e kōkua ana i ka hoʻoponopono pono ʻana i ka noho ʻana.
