ʻO Liprimar a me kona mau mea hoʻohālike, nā koho koho a me nā loiloi

ʻAe, hoʻolālāʻia nā statins a pau i kahi huakaʻi lōʻihi (e komo pū ana me ke ola). Ināʻo ia i kahi maʻi ahonui e hōʻemi pono i ka cholesterol a ʻaʻole i kumu e hoʻonui i ka ALT a me AST (nā enzymes i loko o nā hoʻāʻo ʻana i ke koko), hiki iā ʻoe ke hoʻomau i ka lawe. Eia kekahi, hoʻokahi i kēlā me kēia mahina 6, pono ʻoe e hoʻomaʻi i ka hoʻokahe koko no ka 'lipid profile (cholesterol), ALT, AST.

Liprimar: hana lāʻau lapaʻau, hoʻopili, nā hopena ʻaoʻao

ʻO Liprimar (mea hoʻohana Pfizer, ka ʻāina Kelemānia) ka inoa kālepa inoa inoa inoa no ka lāʻau lapaʻau lipid-hoʻohiolo ʻana. ʻO ka hana ikaika ma loko ia he atorvastatin. ʻO kēia lāʻau lāʻau mai ka pūʻulu o nā statins statins e pili ana i ka cholesterol koko a me nā triglycerides.

Hōʻemi ka liprimar i nā kiko o ka mea i kapa ʻia ka "hewa" kolamu a hoʻonui i ka ʻike o ka "maikaʻi", e hoʻolako ana i ka ʻokiʻoki i ke koko a hōʻemi i ka hana ʻana i nā kahe koko, pale i nā kīʻaha koko a he mea pale ia e pale ʻia ai nā hōʻeha a me nā puʻuwai puʻuwai.

ʻO ke ʻano o ka hoʻokuʻu i ka lypimar he papa elliptical. ʻO ka hewa o ka atorvastatin i loko o lākou he hiki i 10, 20, 40 a me 80 mg, e like me ka hōʻike ʻana ma nā hōʻailona pili i kēlā me kēia papa.

Ma kahi o ia mea, aia ka hoʻomākaukau e pili ana i nā mea kōkua: calcium carbonate, magnesium stearate, croscarmellose sodium, hypromellose, lactose monohydrate, hydroxypropyl cellulose, titanium dioxide, talc, simethicone emulsion.

ʻAʻole pono nā papa Chew. Ua paʻa lākou i ka coated enteric. Hoʻokomo ʻia hoʻokahi papa papa no hoʻokahi lā a i ʻole. Hāʻawi kēlā me kēlā me kēia maʻi pākahi. Inā he hanana overdose o ka lāka, pono e hana ʻia ka nui o ka gastric a pono e kūkā koke ke kauka.

Liprimar: mau hōʻailona no ka hoʻohana ʻana

Ua kuhikuhi ʻia ka lāʻau lapaʻau no nā maʻi aʻe.

• hipololeka,
• a hui pū ʻia
• dysbetalipoproteinemia,
• paulakowalik
• nā hui pilikia no ka hoʻomohala ʻana i ka maʻi naʻau coronary (nā poʻe ma luna o 55, nā mea ulaula, nā mea maʻi me ka maʻi mellitus, ka mana ʻōpiopio, a me nā mea ʻē aʻe).
• maʻi maʻi coronary.

Hiki iā ʻoe ke hoʻohaʻahaʻa i ka kolamu, nānā i kahi meaʻai, hoʻonaʻauao kino, me ka momona me ka hoʻohaʻahaʻa ʻana i ke kaumaha o ka nui o ke kino, inā ʻaʻole kēia mau hana i hāʻawi i nā hopena, e kuhikuhi ana i nā lāʻau lapaʻau e hoʻohaʻahaʻa i ka kolesterol.

Pono pono e hahai i nā ʻōlelo kauoha no ka hoʻohana ʻana o Liprimar. ʻAʻohe wahi palena no ka lawe ʻana i nā pil. Hoʻokumu i nā kuhikuhi o LDL (kino hōʻeha), ke helu ʻia o kēlā me kēia lā o ka lāʻau (maʻamau ka nui 10-80 mg). ʻO ka mea maʻi me kahi puka mua o ka hypercholesterolemia a i ʻole ka hyperlipidemia i hui ʻia e 10 mg, lawe ʻia i kēlā me kēia lā no 2-4 mau hebedoma. ʻO ka poʻe maʻi e hoʻomanawanui i ka hypercholesterolemia hoʻoilina e kuhikuhi i ka nui loa o ke 80 mg.

Koho i nā kaila o nā lāʻau lapaʻau e pili ana i ka metabolism momona e pono e hoʻomake ʻia e nā lipid pae i ke koko.

Me ka mālama aka, ua ʻōlelo ʻia ka lāʻau lapaʻau no ka poʻe maʻi me ka hiki ʻole o ka pale a i ʻole ka hoʻokau ʻia me Cyclosparin (ʻaʻole iʻoi aku ma mua o 10 mg i kēlā me kēia lā), e loaʻa ana i nā maʻi o nā maʻi, nā mea maʻi a i nā makahiki o ke keʻena ʻana.

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana

Loaʻa ma ke ʻano o nā papa, i nā blisters 7 7 mau ʻāpana, ka nui o ka blisters i loko o ka paena he mea like nō hoʻi, mai 2 a 10. ʻO ka mea ikaika e kūleʻe ai ka paʻakai kalima (atorvastatin) a me nā mea hoʻohui hou: croscarmellose sodium, calcium carbonate, candelila wax, small cellulose crystals, hyprolose, lactose monohydrate, polysorbate-80, opadra keʻokeʻo, magnesium stearate, simethicone emulsion.

ʻO nā papa liprimar Elliptical i uhi ʻia me kahi pūpū keʻokeʻo, hilinaʻi ʻia i ka dosage i nā milligrams, i loaʻa ke kahakaha o 10, 20, 40 a i ʻole 80.

He waiwai waiwai

ʻO ka waiwai nui o Liprimar kona hypolipidemia. Kōkua ka lāʻau lapaʻau e hōʻemi i ka hana o nā enzymes e kuleana ai no ka synthesis o kolamu. Ke alakaʻi nei kēia i kahi emi o ka hana o ka kolamu ma ka pepi, kēlā, e hoʻoneʻe i kona pae i ke koko, a hoʻomaikaʻi ka hana o ke ʻano cardiovascular.

Ua kuhikuhi ʻia ka lāʻau lapaʻau no nā kānaka me ka hypercholesterolemia, kahi mea mālama ʻole lapaʻau a me nā lāʻau lapaʻau-hoʻohaʻahaʻa ʻē aʻe. Ma hope o kahi papa o ka papaʻaina, hāʻule nā ​​pae kolamu e 30-45%, a me LDL - e ka 40-60%, a me ka nui o kahi a-lipoprotein i loko o ke koko.

Hāʻawi ka hoʻohana ʻana o Liprimar i ka hōʻemi ʻana i ka hoʻomohala ʻana o nā pilikia hōʻeha o ka naʻau coronary e ka 15%, ua emi iho ka make mai nā pathologies cardiac, a me ka hōʻemi ʻana o ka hōʻeha ʻana i ka naʻau a me nā hōʻino huhū o angina e hoʻemi nei ma 25%. ʻAʻole i ʻike ʻia nā waiwai mutagenic a me ka carcinogenic.

Nā ʻihi ʻaoʻao a Liprimara

E like me nā lāʻau lapaʻau, loaʻa i kēia hopena nā hopena. No Liprimar, ʻo nā ʻōlelo aʻoaʻo no ka hoʻohana ʻana, e ʻae maikaʻi ʻia ka maikaʻi. Eia nō naʻe, ua ʻike ʻia kahi nui o nā ʻaoʻao o ka ʻaoʻao: ʻniania, maʻi ʻehaʻeha o ka maʻi maʻi (asthenia), nā kuʻuna i ka ʻōpū, ka ʻōpū a me ka dyspepsia, pua (flatulence) a me ka constipation, myalgia, nausea.

Nā hōʻailona o ka anaphylaxis, anorexia, arthralgia, ʻehaʻeha a me nā hōʻeha, hypo- or hyperglycemia, dizziness, jaundice, rash skin, itching, urticaria, myopathy, kahaha ka hoʻomanaʻo ʻana, hoʻemi a hoʻonui paha i ka hōʻanoho ʻana, ka neuropathy, pancreatitis, hoʻomaʻamaʻa, ʻomaʻama ʻaʻole pinepine ke nānā ʻia. thrombocytopenia.

ʻO nā ʻaoʻao ʻaoʻao o Liprimar i nānā ʻia, e like me ke kaʻe ʻana o nā limahana, ka momona, ka ʻeha o ka ʻōpū, alopecia, tinnitus, a me ka hoʻomohala ʻana o ka hana renal lua ʻole.

Nā Hoʻohui

No nā mea maʻi me ka hypersensitivity i nā mea e hoʻomālamalama ʻia ai a Liprimar, ua contraindicated ka lāʻau lapaʻau. ʻAʻole i kuhikuhi ʻia no nā keiki ma lalo o 18 makahiki. ʻO ka poʻe maʻi e hoʻomanawanui nei mai nā maʻi hepatic ikaika a i ʻole ke kiʻekiʻe kiʻekiʻe o ka transaminases i ke koko o ka ʻike ʻole etiology.

Ke pāpā nei nā mea hana o Liprimar i ka hoʻohana ʻana i ka lāʻau lapaʻau i ka wā lactation a me nā hapai. Pono nā wahine o ka wā hānau keiki e hoʻohana i nā ʻikena i ka wā mālama. ʻO ka loaʻa ʻana o ka wā hāpai i ka wā e mālama ai me ka lāʻau lapaʻau he mea kūpono ʻole ia, no ka mea he hiki ke hoʻopilikia maikaʻi ʻia i ka hiki ʻana o kahi wī.

Pono e hoʻomaopopo ʻia ka lāʻau lapaʻau me ka mālama pono ʻana i nā poʻe me ka mōʻaukala o nā maʻi ʻehaʻi a i ʻole hōʻino i ka wai ʻona.

Nā Hōʻike

Atorvastatin - kahi hui o Liprimar - kekahi o nā lāʻau kaulana loa no ka hoʻohaʻahaʻa ʻana i nā lipoproteins haʻahaʻa-haʻahaʻa. Ua hōʻike ʻia nā hoʻokolohua mālama ʻia e Grace a me 4S ka nui o ka atorvastatin ma luna o simvastatin i ka pale ʻana i ka hoʻomohala ʻana i ka maʻi cerebrovascular acute a me ka maʻa. Ma lalo nei mākou e noʻonoʻo ai i nā lāʻau lapaʻau o ka pūʻulu statin.

Nā huahana e pili ana i Atorvastatin

ʻO ka analogue Lūkini o Liprimar, Atorvastatin, e hana i nā huahana lāʻau lapaʻau: Kanofarma Production, ALSI Pharma, Vertex. Nā papa waha me ka nui he 10, 20, 40 a i ʻole 80 mg. Lawe hoʻokahi lā i kahi lā ma kahi o ka wā like, me ka ʻole o nā meaʻai.

Kū pinepine nā mea hoʻohana iā lākou iho - Atorvastatin a i ʻole Liprimar - ʻoi aku ka maikaʻi?

Hoʻohālikelike ka hana o ka lāʻau lapaʻau ma Atorvastatin i ka hana a Liprimar, no ka mea, ʻo nā hua lāʻau i ke kumu ke like me nā mea like. Ka hana o ka hana o ka lāʻau mua me ka hoʻonāukiuki ʻana i ka synthesis o nā kolala a me nā lipoproteins atherogenic e nā mea ponoʻī ponoi o ke kino. Hoʻohana nui ka hoʻohana ʻana o LDL i nā pūpuna o nā nāhelehele, a me ka nui o ka hana o ka lipoproteins anti-atherogenic kiʻekiʻe-density density nui hoʻi ka nui.

Ma mua o ke koho ʻana iā Atorvastatin, ua hoʻoponopono ʻia ka mea maʻi i kahi mea ʻai a kuhikuhi i kahi papa hana, ʻike ia i kēia manawa i ka hopena maikaʻi, a laila ke kuhikuhi ʻana i nā statins i mea pono ʻole ʻole.

Inā hiki ʻole ke hoʻākohala pono i ka pae o ka cholesterol me ka lāʻau ʻole-lāʻau, nā lāʻau lapaʻau o kekahi pūʻulu o nā statins i kuhikuhi ʻia, ʻo ia ka Atorvastatin.

I ka hoʻomaka mua o ka hoʻōla, hāʻawi ʻia ʻo Atorvastatin i 10 mg hoʻokahi i ka lā. Ma hope o nā hebedoma e 3-4, inā e koho pololei ʻia ka nui o nā hewa, e ʻike ʻia ana ka loli o ka lehelehe lipid I ka ʻōlelo lipid, ua hoʻomaopopo ʻia ka emi ʻana o ka cholesterol nui, ua emi ka nui o ka lipoproteins haʻahaʻa haʻahaʻa a haʻahaʻa, i ka nui o ka triglycerides e emi.

Inā ʻaʻole i loli a ʻaʻole hoʻi i hoʻonui iki paha ka nui o kēia mau mea, pono e hoʻoponopono i ka maʻi o Atorvastatin. Loaʻa i ka lāʻau lapaʻau i loaʻa i nā ala he nui, kūpono loa ia no nā mea maʻi e loli. 4 mau pule ma hope o ka hoʻonui ʻana i ka nui o ka pane, ua hoʻomau ʻia ka loiloi spekulopa, inā pono, hoʻonui hou ʻia ka nui, ʻo 80 ka nui o kēlā me kēia lā.

Ka like o ka hana o ka hana, ke ʻano a me nā hopena ʻokoʻa o Liprimar a me kāna hoa ʻeka Lūkini. Loaʻa nā pono o Atorvastatin i kāna kumukūʻai kūpono. Wahi a nā loiloi, pinepine pinepine ka lāʻau Lūkini i nā hopena ʻaoʻao a me nā maʻi pākuʻi ʻia me Liprimar. Aʻo kahi drawback kahi lōʻihi lōʻihi.

ʻO nā koho ʻē aʻe no Liprimar

Ieiʻi - kahi moʻolelo o Liprimar – lāʻau lapaʻau i hana ʻia e ka hale kūʻai lāʻau lapaʻau Slovenian o KRKA. ʻO ia nō hoʻi ka lāʻau lapaʻau e like me kāna hana a ka lāʻau lapaʻau me Liprimaru. Loaʻa nā Atoris me kahi pālahalaha he nui ʻē aʻe i hoʻohālikelike ʻia me Liprimar. Mālama kēia i ke kauka i ka maʻalahi o ka helu ʻana i ka wai, a hiki i ka mea maʻi ke lawe i ka lāʻau.

ʻO Atoris wale nō ke ʻano o ka lāʻau lapaʻau (Liprimara generic) i hana i ka nui o nā hoʻokolohua hoʻomaʻamaʻa a ua hōʻoia i ka hana pono. Ua hele pū nā mea kōkua mai nā ʻāina he nui i kāna aʻo ʻana. Ua hana ʻia ke aʻo ʻana ma nā kumu o nā haukapila a me nā haukapila. I ka hopena o nā haʻawina ma 7000 mau kumuhana e lawe nei i ka Atoris 10 mg no 2 mau mahina, ua ʻike ʻia kahi kahe o ka atherogenic a me ka kolamu nui ma ka 20-25% ʻO ka liʻiliʻi o ka hopena pili i Atoris he liʻiliʻi.

ʻO Liptonorm kahi lāʻau Lūkini e hoʻomaʻamaʻa i nā metabolism momona i ke kino. ʻO ka mea hana i loko o ia mea he atorvastine, kahi mea me ka hana hypolipidemic a me ka hana hypocholesterolemic. He like nā hōʻailona like me ka liptonorm no ka hoʻohana ʻana a me ka maʻi ʻana me Liprimar, a me nā hopena like.

Loaʻa ka lāʻau lapaʻau i nā mea ʻelua wale nō o 10 a 20 mg. He mea paʻakikī loa ia no ka hoʻohana ʻana e nā mea maʻi e hōʻeha nei i nā ʻano hana ʻino o ka atherosclerosis, hechrolesterolemia famihilau heterozygous, pono lākou e lawe i nā papa he 4-8 i kēlā me kēia lā, ʻoiai ka lula i kēlā me kēia lā he 80 mg.

ʻO Torvacard ka analoge kaulana loa o Liprimar. Hoʻopau i nā hua lāʻau lapaʻau Slovak "Zentiva". Ua hoʻokūpaʻa ʻo "Torvacard" iā ia iho no ka hoʻoponopono ʻana o ka cholesterol i nā mea maʻi e loaʻa mai ana i ka pathology cardiovascular. Hoʻohana maikaʻi ia e mālama i nā mea maʻi me ka cerebrovascular maʻi a me ka coronary insufficiency, me ka pale ʻana i nā hoʻopiʻi e like me ka hōʻeha a me ka puʻuwai puʻuwai. ʻO ka lāʻau lapaʻau ka hōʻemi haʻahaʻa i ka pae o ka triglycerides i ke koko. Hoʻohana hou ia ma ka mālamaʻana i nā hua hoʻoilina o ka dyslipidemia, no ka laʻana, e hoʻonui ai i ka pae o ka "lipoproteins" high-density lipoproteins.

Nā ʻano hana i hoʻokuʻu ʻia "Torvokard" 10, 20 a me 40 mg. Hoʻomaka ka lāʻau atherosclerosis, maʻamau me ka 10 mg, ma hope o ka hoʻopaʻa ʻana i ke kiʻekiʻe o ka triglycerides, cholesterol, nā lipoproteins haʻahaʻa haʻahaʻa. Ma hope o 2 mau hebedoma e hana ana i ka nānā ʻana i ka loiloi o ka hoʻopuni hoʻopunipuni o ka lipid. Me ka loaʻaʻole o ka mālamaʻana, e hoʻonui i ka dosage. ʻO ka palena kiʻekiʻe loa i kēlā me kēia lā he 80 mg.

ʻAʻole like me Liprimar, ʻoi aku ka maikaʻi o Torvacard i nā mea maʻi me nā maʻi o ka ʻōnaehana cardiovascular, ʻo ia nō "+".

ʻO ka lāʻau lapaʻau ka lypimar. Ke aʻo a me ka uku kumu

Pono e nānā mua i nā lāʻau lapaʻau me ka hoʻāʻo e hoʻohaʻahaʻa i ka cholesterol me nā nā loli, ke ʻano, ke hoʻonaʻauao kino. Inā nele ʻole kēia, kuhikuhi i ka lāʻau lapaʻau. Ma mua o ka hoʻomaka ʻana e lawe i nā papa Lyprimar, pono e heluhelu ʻia nā ʻōlelo aʻoi aku me ka ʻole o ka pau.

Manaʻo nā kauka e lawe mau iā ia, akā naʻe ʻo ke kumukūʻai o ka lāʻau lapaʻau ʻaʻole ka mea haʻahaʻa: ma kahi o 1800 rubles. per 100 papa ma ka palena haʻahaʻa o 10 mg. No laila, nui nā mea maʻi e ʻimi ana i ka analogues o lypimar, ʻoi aku ka mea maʻalahi i ka mea mua, akā i ka hopena like.

Ma mua o kā mākou papa inoa i nā mea hoʻohālike o kēia lāʻau lapaʻau, ke manaʻo nei mākou he mea pono e ʻōlelo e pili ana i ka pona kumu no nā ʻoihana Pfizer, a me nā hui analog e haʻahaʻa loa ana i loaʻa ka hopena kūpono i kou kino a alakaʻi paha i nā hopena maikaʻi ʻole hou aku i ka lypimar. No laila, ma mua o ke kau ʻana i ka lāʻau lapaʻau, e nīnau aku i kāu kauka.

Liprimar. Nā hopena hopena

ʻO kēia ka kolu o ka hanauna o nā statins, no laila e hana pono i ke kino me ka liʻiliʻi a loaʻa ka hopena i nā ʻaoʻao. Kau he luhi loa ka hōʻike, akā ʻike ia. Me ka hoʻohana mau ʻana i nā papa kiʻekiʻe o ka lāʻau lapaʻau, hiki ke hoʻomaopopo ʻia ka hoʻomanaʻo ʻana a me ka noʻonoʻo ʻana, a me nā pilikia pāpaʻi ʻana, ka ʻeha o ka naʻau, nā luhi, ka hiamoe, ke poʻo, ka hoʻomaha hiamoe.

He mea kūpono ke hoʻomanaʻo no ka piʻi ʻana o ka maʻi diabetes i ka wā e lawe ai i kēia lāʻau lapaʻau. Ma kēia hihia, ua hoʻoholo ke kauka i ka mea nui loa no ka mea maʻi: he lāʻau lapaʻau i hōʻemi ʻia i ka cholesterol a mālama i nā waiwai o ke kō.

ʻO ka lāʻau lapaʻau ka lypimar. Nā hōʻailona no ka hoʻohana ʻana

Ua kuhikuhi ʻia ka lāʻau lapaʻau no nā pākeke a me nā keiki me ka kiʻekiʻe o ka cholesterol i ke koko.

Hōʻike pū ʻia nā hōʻike komo ʻana:

1. Puʻuwai pale pale,
2. ʻ preventionlelo i ka ʻeha
3. Paipaiʻole o Atherosclerosis
4. Hertertension
5. Nā kūlana ma hope o ka maʻi vascular.

Hoʻokomo ʻia ka lāʻau lapaʻau i ka wā hāpai, ka umauma, ka poʻe e hōʻeha nei i nā maʻi o ke ake, me ka hoʻomanawanui ʻole i nā mea o ka lāʻau.

Atorvastatin

ʻO ka lāʻau lapaʻau e like me ka inoa me ka mea hana. Nui nā hale kūʻai lāʻau Lūkini hua ʻia ka atorvastatin i loko o kahi waihona o 10, 20, 40 a me 80 mg. Lawe ʻia kekahi manawa hoʻokahi i kēlā lā, me ka manaʻo o ka kau ʻana i ka meaʻai. ʻO ka hana ikaika i ka lypimar a me ka atorvastatin ka like.

Hiki ke nānā ʻia ka maikaʻi o ka lāʻau lapaʻau ma o ka hoʻolilo ʻana i kahi loiloi no kahi kolamu e pili ana i hoʻokahi mahina ma hope o ka hoʻomaka ʻana o ka mālama ʻana. Me nā kūpono kūpono, e emi ka hopena i loko. Inā ʻaʻole kēia ka hihia, a laila pono ke kauka ke hoʻoponopono i ka dosage.

ʻOiai ka loaʻa ʻana o atorvastatin i nā ʻanoʻokoʻa like ʻole, ka hoʻololi ʻana i kahi kiʻekiʻe kiʻekiʻe ʻaʻole paʻakikī. Ma hope o hoʻokahi mahina, ua hana hou ʻia ka hana loiloi, a ua huli ʻia nā manaʻo e pili ana i ka hoʻolālā e lawe i ka lāʻau lapaʻau ma.

ʻAʻole maikaʻi nā loiloi o nā kauka e pili ana i kēia lāʻau lapaʻau e like me ka lymparira kumu. ʻO ka emi ʻana o nā lāʻau lapaʻau ma muli o ka hopena liʻiliʻi i ka hoʻohaʻahaʻa ʻana i ka cholesterol a ʻoi aku nā huaʻōlelo ʻē aʻe e kū mai ana ma luna o ka ate.

Ma muli o ke ʻano o kēia mīkini hana i loko o Lūkini, ʻoi aku ka nui o kona kumu. He pālaha o 90 mau papa o atorvastatin 10 mg kēlā me kēia kumukūʻai e pili ana i ka 450 rubles, a me 90 mau papa o 20 mg kēlā me kēia kumukūʻai 630 rubles. No ka hoʻohālikelike: lypimar 20 mg, ke kumukūʻai ma 100 pcs no 2500 mau rubles.

ʻO ka hana like no kēia, ʻo ka mea hana no ka pūnaewele ʻoKAU KRKA. He nui e loaʻa ai nā ʻōhua: 10, 20, 30, 60, 80 mg. No laila, he nui nā manawa o ke kauka i ke koho ʻana i ke ʻano kūpono kūpono no ka mea maʻi. ʻO kēia hōʻaha he mea liʻiliʻi o ka mea i hōʻoia ʻia i loko o ia hana, ʻaʻole ia he hewa ma mua o ka lāʻau lapaʻau mua.

Ua mālama ʻia nā haʻawina ma nā ʻāina he ʻumikūmālua, ua hōʻike ʻia nā hoʻokolohua ma nā hauka a me nā haukapila. Ehiku mau tausani e lawe ana i ka atoris i hōʻike i ka emi o ka cholesterol ma kahi o kahi hapaha o nā waiwai mua. ʻO ka hopena o nā hopena hopena he haʻahaʻa, e like me ka lypimar.

I ka hoʻomaka ʻana o 2017kahi pā o 90 mau papa o atoris 10 mg kumukūʻai e pili ana i 650 rubles., ma kahi pākiha o 40 mg, hiki ke kūʻai ʻia he 30 papa no ka 590 mau rubles. Hoʻohālikelike: liprimar 40 mg (mau ʻōlelo no ka hoʻohana ʻana i ka ʻaʻī), kumukūʻai - 1070 rubles.

ʻO ka mea hana pono o ka hui ʻoihana kūʻē Lūkini. ʻO ka mea koʻikoʻi, nā hōʻailona hōʻailona e pili ana i ka lypimar, akā Loaʻa ka Liptonorm i loko o ʻelua mauʻuana: 10 a 20 mg. No laila, ʻo kēlā mau mea maʻi e pono ai i kahi maʻa nui e loaʻa i nā papa he: 4 a ʻo 8 paha.

ʻO ka mea pōʻino, ʻo ka papa inoa o nā hopena ʻaoʻao o ka liptonorm he ākea nui. Hiki i ka insomnia, dizziness, glaucoma, heartburn, constipation, diarrhea, flatulence, eczema, seborrhea, urticaria, dermatitis, hyperglycemia, nā lilo momona, exacerbation o ka gout a me nā mea hou aku.

ʻO kahi pepa he 28 mau papa o Liptonorm 20 mg mau kumukūʻai 420 mau rubles.

ʻO kekahi lypimar kaulana kaulana loa. Hana ʻia ia ma Slovakia e Zentiva. Aia i kona kū pono i Ua hōʻike ʻia ka hoʻoponopono ʻana o ka cholesterol, no laila ke kuhikuhi ʻia nei e nā kauka. Ka wā: 10, 20, 40 mg.

Hoʻomaka ka loaʻa ʻana o kahi torvakard me 10 mg i ka lā a e hana i ka nānā ʻana i nā kaohi ma kahi mahina. Inā hoʻomaopopo ʻia ko lākou mau dinamika maikaʻi, hoʻomau ka mea maʻi i ka lāʻau like o ka lāʻau. Inā ʻaʻole, ua hoʻonui ʻia ka momona. ʻO ka nui loa o nā lā ma kēlā me kēia lā he 80 mg a i ʻole 2 papa o 40 mg.

He pākahi o 90 mau papa o 10 mg o ka torvacard e pili ana i 700 rubles. (Pepeluali 2017)

ʻO Rosipuvastatin e pili ana i nā liprimar e pili ana i Liprimar

ʻO Rosuvastatin ka lāʻau ʻehini statin ʻehā i ka hika i ke koko a loaʻa iā ia kahi hopena lipid-hoʻemi. ʻO ka hoʻohaʻahaʻa haʻahaʻa a me ke aʻi a me nā meaʻawaʻewa, no laila ke hōʻemi ʻia ka hopena o ka hopena maikaʻi ʻole i ke akea.

Ma kona hopena, ua like ka rosuvastatin me ka atorvastatin, akā he wikiwiki ka hopena. Hiki ke koho ʻia ka hopena o kāna hana ma hope o ka hebedoma, hiki i ka hopena kūpono ke loaʻa i ka hopena o ke kolu a ʻehā paha pule.

ʻO nā lāʻau lapaʻau kaulana kaulana e pili ana i ka rosuvastatin:

• Crestor (Astrazeneca Pharmaceuticals, UK). 98 mau papa o 10 mg kumukūʻai 6150 rubles.,
• Mertenil (Gideon Richter, Hanau). 30 mau papa o 10 mg kumukūʻai 545 rubles.,
• Tevastor (Amma, Israel). 90 papa o 10 mg kumukūʻai 1,100 rubles.

ʻO nā kumukūʻai ma ka hoʻomaka o 2017.

Ka hana lāʻau lapaʻau

ʻO ka lipid-liped Synthetic lāʻau. ʻO Atorvastatin he mea mālama i ka hoʻokūkū koho o HMG-CoA reductase, he kīme nui e hoʻohuli ana i ka 3-hydroxy-3-methylglutaryl-CoA i mevalonate, kahi mea i mua i ka lāʻau, a me ka kolamu.

I nā maʻi me ka homozygous a heterozygous familial hypercholesterolemia, non-familial form of hypercholesterolemia and mixed dyslipidemia, atorvastatin lowers total cholesterol (Ch) in plasma, cholesterol-LDL a me apolipoprotein B (apo-B), a e hoʻolauna pū iā TG-C a me TG ka hoʻonui pinepine ʻole ma ka pae o HDL-C.

Hoʻopili ke Atorvastatin i ka hoʻoneʻe ʻana o ka kolamu a me nā lipoproteins i loko o ke koko koko, e hoʻoneʻe ana i ka hoʻōla ʻana o HMG-CoA a me ka synthesis o ka kolamu o ka ate a me ka hoʻonui ʻana i ka nui o nā mea hoʻokipa LDL hepatic ma luna o ka pūlaka, kahi e hoʻonui ai i ka hoʻonui a me ka catabolism o LDL-C.

Hoʻopili ke Atorvastatin i ka hoʻokumuʻana o LDL-C a me ka nui o nā māhele LDL. Hoʻokumu ia i ka hoʻonui i hoʻomau a hoʻomau i ka hana o nā mea LDL e komo pū ai, a hui pū me nā loli qualitative maikaʻi loa i nā hapa LDL. Hoʻēmi i ka pae o ka LDL-C i nā mea maʻi me ka hypercholesterolemia homozygous me ka pale ʻana i ka lāʻau lapaʻau me nā lāʻau lapaʻau ʻē aʻe.

I ka mālamaʻana o Atorvastatin i nā wai o 10-80 mg e hoʻemi i ka pae o ka kolamu o ka nui o ka 30-46%, LDL-C e 41-61%, apo-B e 34-50% a me TG e 14-33%. Hoʻohālike nā hopena lapaʻau i nā mea maʻi me ka heterzygous famamial hypercholesterolemia, ʻaʻohe ʻohana ʻohana o hypercholesterolemia a me ka hyperlipidemia i hui pū ʻia, me ka komo pū i nā mea maʻi me ka diabetes-mellitus-non-diabetes mellitus.

I nā maʻi me ka hypertriglyceridemia hoʻokaʻawale, hōʻemi loa ʻo atorvastatin i ka kolamu a pau, Chs-LDL, Chs-VLDL, apo-B a me TG a hoʻonui i ke kiʻekiʻe o Chs-HDL. I nā maʻi me ka dysbetalipoproteinemia, e hōʻemi ana i ka pae o ChS-STD.

I ka poʻe maʻi me ka type IIa a me IIb hyperlipoproteinemia e like me ka helu ʻana o Fredrickson, ʻo ka nui o ka piʻi ʻana o ka hoʻonui ʻana o HDL-C i ka wā mālama me ka atorvastatin (10-80 mg), i hoʻohālikelike ʻia me ka waiwai mua, ʻo ia ka 5.1-8.7% a ʻaʻole i hilinaʻi ma ka ʻōlelo. Aia ka nui o ka hoʻoliʻiliʻi a hilinaʻi nui i ka pae: ʻo ka kolamu piha / Chs-HDL a me Chs-LDL / Chs-HDL e ka 29-44% a me 37-55%, ia manawa.

ʻO Atorvastatin ma kahi o 80 mg e hoʻohaʻahaʻa nui loa i ka hōʻeha o nā maʻi ischemic a me ka make e 16% ma hope o kahi papa 16 wiki, a me ka hopena o ka hoʻoliʻi hou ʻana no ka angina pectoris, i hui pū ʻia e nā hōʻailona o ka ischemia myocardial, e 26%. I nā mea maʻi me nā pae baseline like ʻole o ka LDL-C, hiki i ka atorvastatin ka hopena o ka hōʻemi o ka hoʻopiʻi ischemic a me ka make (i nā mea maʻi me ka myocardial infarction me ka hawewe Q a me ka pupule mau ʻole, nā kāne a me nā wahine, nā mea maʻi ma lalo o 65 mau makahiki).

ʻO ka emi ʻana o nā pae plasma o LDL-C ka mea i ʻoi aku me ka maikaʻi o ka lāʻau lapaʻau ma mua o kona hoʻomoʻa ʻia i ka plasma koko.

Loaʻa ka hopena therapeutic i 2 mau pule ma hope o ka hoʻomaka ʻana o ka hōʻola, a hiki i ka nui loa ma hope o 4 mau hebedoma a hoʻomau i ka holoʻokoʻa o ka wā mālama.

Kāohi pilikia Cardiovascular

I ka noi ʻana o Anglo-Scandinavian o ka hopena o ka hopena cardiac, ka lālā lipid-hina i haʻahaʻa (ASCOT-LLA), ua ʻike ʻia ka hopena o ka atorvastatin ma ka maʻi o ka mea make a me ka mea momona, ʻaʻole i loaʻa ka hopena o ka hopena o ka hopena atorvastatin ma ke ʻano o 10 mg nui i ka hopena o ka plasebo, a no laila ua hoʻoholo ʻia. nā haʻawina ma hope o 3.3 mau makahiki ma mua o ka manaʻo he 5 mau makahiki.

Ua hoʻemi nui ʻia ʻo Atorvastatin i ka hoʻomohala ʻana o nā hoʻopiʻi hou aʻe nei:

ʻAʻole i emi nui i loko o ka make a me ka make ma hope o ke kino make, ʻoiai he mau kūpono kūpono.

I ka hui pū ʻana o ka hopena o ka atorvastatin i nā mea maʻi me ka maʻi diabetes mellitus type 2 (CARDS) i ka hopena hōʻeha a me ka mea ʻole ke make o nā maʻi cardiovascular, hōʻike ʻia ʻo ia ka mālama ʻana me ka atorvastatin, ka manaʻo ʻole o ke kāne maʻi, ʻokoʻa, a i ʻole pae o LDL-C, hoʻemi i ka pilikia o ka hoʻomohala ʻana i nā maʻi cardiovascular e hiki mai ana. :

I loko o ka noiʻi ʻana i ka hoʻomohala ʻana o ka atherosclerosis coronary me ka ʻeha hypolipidemic therapy (REVERSAL) me ka atorvastatin ma kahi pākēpē o 80 mg i nā mea maʻi me ka maʻi ʻalihi coronary, ʻike ʻia ka nui o ka hoʻemi ʻana o ka nui o ka atheroma (ka hapa mua o ka hoʻomaʻamaʻa) mai ka hoʻomaka ʻana o ka noi ʻana he 0.4%.

Ma ka Intensive Cholesterol Reduction Program (SPARCL) ʻike i ka atorvastatin ma ke ʻano o 80 mg i kēlā me kēia lā i hōʻemi ʻia ka hopena o ka hōʻeha hou ʻana a i ʻole ka make i ka maʻi maʻi i loaʻa i ka moʻolelo o ka hōʻeha a i ʻole ka maʻi ischemic attack me ka ischemic heart heart e ka 15%, i hoʻohālikelike ʻia me ka placebo. I ka manawa like, ua hoʻemi nui ʻia ka loaʻa ʻana o ka hōʻeha o nā ʻōkuhi a me ka hōʻola hou aku i nā loiloi. ʻO ka hōʻemi ʻana i ka hopena o ka maʻi cardiovascular i ka wā o ka lapaʻau me ka atorvastatin i nānā ʻia i loko o nā hui āpau koe wale nō ka mea i komo i nā mea maʻi me ka maʻi hemorrhagic mua a i ʻole (7 i ka hui atorvastatin ma 2 i ka hui pletebo).

I loko o nā mea maʻi i mālama ʻia me ka hopena atorvastatin ma ke ʻano o 80 mg, i ka loaʻa ʻana o ka hemorrhagic a i ʻole ischemic stroke (265 ma mua o 311) a i ʻole IHD (123 kūmole 204) ka liʻiliʻi ma mua o ka pūʻulu mana.

Kākoʻo pale ʻelua o nā pilikia hoʻonā

Ma nā ʻōlelo o ka New Target Study (TNT), ua hoʻohālikelike ʻia nā hopena o ka atorvastatin ma nā kikowaena o 80 mg i kēlā me kēia lā a me 10 mg i kēlā me kēia lā ma ka pilikia o ka hoʻomohala ʻana i nā hoʻopiʻi cardiovascular ma nā maʻi me ka maʻi paʻa o ka maʻi coronary i hoʻopaʻa ʻia ma ka maʻi.

Atorvastatin ma ke ʻano o 80 mg hoʻohaʻahaʻa nui ʻia ka hoʻomohala ʻana o kēia mau ʻōlelo hoʻopiʻi:

Lapaʻau lāʻau

Hoʻopili wikiwiki ʻia ʻo Atorvastatin ma hope o ka lawelawe ʻana o ka waha, Cmax i loaʻa ma hope o nā hola 1-2. ʻO ke kūmole o ka hoʻomoʻi ʻana a me ka hoʻokūkū o ka atorvastatin i ka plasma koko hoʻonui i ka nui o ka pākī. ʻO ka bioavailability piha o atorvastatin ma kahi o 14%, a me ka bioavailability o ka ʻōnaehana o ka hana pale ma ka HMG-CoA reductase ma kahi o 30%. ʻO ka bioavailability haʻahaʻa haʻahaʻa ma muli o ka metabolism presystemic i ka mucosa gastrointestinal a me / a i ka wā o ka "papa mua" ma o ka ate. Hōʻemi ka meaʻai i ka nui a me ka nui o ka inu ʻana ma kahi o 25% a me 9%, kēlā, e like me ka hōʻike ʻia e nā hopena o ka hopena o Cmax a me AUC) naʻe, i ka pae o ka LDL-C i ka wā e lawe ana i ka atorvastatin ma kahi ʻōpū ʻole a ma ka wā ʻaina e emi ma lalo o ka like. ʻOiai ka hopena ma hope o ka lawe ʻana i ka atorvastatin i ke ahiahi, ua emi iho kona pae plasma (Cmax a me AUC ma kahi o 30%) ma hope o ka lawe ʻana i kakahiaka, akā, ʻaʻole i hilinaʻi ʻia ka hōʻemi o LDL-C i ka manawa o ka lā e lawe ʻia ai ka lāʻau.

ʻO ka awelika Vd o atorvastatin he 381 lita. ʻO ka paa ʻana o ka atorvastatin i nā protein plasma ma kahi o 98%. ʻO ka ʻike o ka pae o ka atorvastatin ma loko o nā kaila koko / koko plasma ma kahi o 0.25, i.e. ʻaʻole komo ʻo atorvastatin i nā ʻāpana koko ʻaʻī.

Hoʻohā nui ʻia ka Atorvastatin e hana i nā derivatives ortho- a para para-hydroxylated a me nā huahana beta-oxidation. In vitro, ortho- a me para-hydroxylated metabolites he hopena pale i ka HMG-CoA reductase, i hoʻohālikelike ʻia i ka atorvastatin. ʻO ka hana pale i ka HMG-CoA reductase ma kahi o 70% ma muli o ka hana o nā neʻe ʻana i nā metabolites. I loko o nā haʻawina vitro hōʻike ana i ka isoenzyme CYP3A4 hana koʻikoʻi i ka hana o ka metabolism o atorvastatin. Hoʻomaopopo ʻia kēia ma ka hoʻonui ʻia o ka atorvastatin i loko o ke koko koko o ke kanaka i ka wā e lawe ana i ka erythromycin, ʻo ia ka mea e hoʻomehana ai i kēia isoenzyme.

Ua hōʻike pū ʻia nā haʻawina vitro he atorvastatin kahi mea palupalu ikaika o ka isoenzyme CYP3A4. ʻAʻohe hopena koʻikoʻi ʻo Atorvastatin i ka paʻa ʻana o ka terfenadine i loko o ke kaila koko, ka mea i koho ʻia e ka isoenzyme CYP3A4, i kēia mea, i ka hopena nui o ka atorvastatin ma ka pharmacokinetics o nā mea hou aʻe o ka isoenzyme CYP3A4 i like ʻole.

Hoʻokomo ʻia ʻo Atorvastatin a me kāna mau metabolite me ka bile ma hope o ka hepatic a / a i ʻole metabolism nui aʻe (atorvastatin ʻaʻole i pau i ka enterohepatic recirculation). Ma kahi o 14 mau hola he T1 / 2, ʻoiai ka hopena o ka hopena o ka lāʻau kūʻē i ka HMG-CoA reductase ma kahi o 70% e hoʻoholo ana e ka hana o ka hoʻopuni ʻana i nā metabolites a hoʻomau mau paha no nā hola 20-30 ma muli o ko lākou heleʻana. Ma hope o ka lawelawe waha, ua emi iho ma lalo o 2% o ka make o ka atorvastatin e ʻike ʻia i ka urin.

ʻO ka pharmacokinetics i nā hihia lapaʻau kūikawā

ʻO ke kaila o ka plasma o ka atorvastatin i nā ʻelemakule (mau makahiki he 65 mau makahiki) ʻoi aku ka nui (Cmax ma kahi o 40%, AUC ma kahi o 30%) ma mua o nā maʻi maʻi o nā makahiki ʻōpio. ʻAʻohe ʻokoʻa nā ka palekana, ka hopena, a me ka hoʻokō ʻana i nā pahuhopu o ka hoʻomaʻamaʻa ʻana o lipid-hoʻohiolo i ka poʻe ʻelemakule i hoʻohālikelike ʻia me ka lehulehu.

ʻAʻohe hana i hōʻike ʻia i ka pharmacokinetics o ka lāʻau i nā keiki.

Nā ʻokoʻa o ka pehu o ka atorvastatin i nā wahine (Cmax ma kahi o 20% kiʻekiʻe, a ʻo AUC ma ka 10% mau haʻahaʻa) mai kēlā mau kāne. Eia nō naʻe, ʻaʻole i ʻike ʻia nā ʻokoʻa koʻikoʻi o nā maʻi i ka hopena o ka lāʻau ma ka lipid metabolism i nā kāne a me nā wahine.

Hoʻopilikia i ka hana renal pale i ka hoʻopili ʻana i ka atorvastatin i loko o ke kaila koko a i kona hopena ma nā lipid metabolism. Ma kēia noʻonoʻo, ʻaʻole pono ka loli ʻana o ka dosis ma nā maʻi me nā hana renal impaired.

ʻAʻole i hoʻoiho ʻia ʻo Atorvastatin i ka wā hemodialysis ma muli o kahi paʻa paʻa i ka protein plasma.

Hoʻonui nui nā mea kū i ka Atorvastatin (Cmax a me AUC ma kahi o 16 a me 11 mau manawa, kēlā) i nā mea maʻi me ka cirrhosis alikaola (papa B ma ka pēpē ʻAno-Pugh).

Nā hōʻailona no ka hoʻohana ʻana i ka lāʻau LIPRIMAR®

• hypercholesterolemia maʻamau (heterozygous familial a non-familial hypercholesterolemia (type IIa e like me ka helu o Fredrickson),
• hui ia (hui pū ʻia) hyperlipidemia (nā ʻano IIa a me IIb e like me ka helu ʻana o Fredrickson).
• dibetalipoproteinemia (type III e like me ka helu ʻana o Fredrickson) (me ka hoʻohui o ka ʻai)
• hypertriglyceridemia familial (ʻano IV ma muli o ka helu ʻana o Fredrickson), kū i kaʻai,
• homozygous famchial hypercholesterolemia me ka lawa ʻole o ka hana o kaʻai ʻana i ka papa ʻaina a me nā ʻano ʻē aʻe non-pharmacological o ka maʻi.
• ka pale mua ʻana o nā hoʻopiʻi cardiovascular ma nā mea maʻi me nā hōʻailona ʻole o ka maʻi coronary heart disease, akā me kekahi mau mea pili i ka ulu ʻana - ʻoi aku ka makahiki ma mua o 55 mau makahiki, ka hoʻohui ʻana ʻo nikotine, hypertension arterial, diabetes mellitus, nā haʻahaʻa haʻahaʻa o HDL-C i ka plasma, predisposition genetic, etc. h ^ ʻoi e kū'ē ana i ke aniani o dyslipidemia,
• pale aku i ka lua o nā hoʻopiʻi cardiovascular ma nā mea maʻi me ka maʻi puʻuwai coronary e hōʻemi i ka nui o ka make me ka nui, myocardial infarction, stroke, re-hospitalization no angina pectoris a me ka pono no ka revascularization.

ʻLoe a me ke kākele

Ma mua o ka hoʻomaka ʻana i ka mālama ʻana me Liprimar, pono e hoʻāʻo e hoʻokō i ka hoʻomohala ʻana i ka hypercholesterolemia me ke kōkua o ka ʻai ʻana, hoʻōla a me ka hoʻolilo ʻana i ke kaumaha ma nā mea maʻi me ka momona, me ka mālama ʻana i ka maʻi kumu.

Ke hoʻoholo nei i ka lāʻau lapaʻau, pono ke hoʻomau i ka mea maʻi i kahi meaʻai hypocholesterolemic maʻamau, pono ia e hahai i ka wā o ka mālama ʻana.

Lawe ʻia ka lāʻau lapaʻau i kēlā me kēia manawa o ka lā, me ke ʻano o ka komo ʻana o ka meaʻai. Hoʻololi ʻia ka ʻano o ka lāʻau lapaʻau mai 10 mg a 80 mg i hoʻokahi manawa i ka lā, e lawe ʻia ke koho o ka ʻikepili me ka noʻonoʻo ʻana i nā pae mua o ka LDL-C, ke kumu o ka hoʻomohala a me ka hopena pilikino. ʻO ka dosis kiʻekiʻe loa he 80 mg hoʻokahi i ka lā.

I ka hoʻomaka ʻana o ka hoʻōla a me / a i ka manawa o ka hoʻonui ʻana i ka mahele o ka liprimar, pono ia e nānā i ka maʻi lipid plasma ma kēlā me kēia mau hebedoma 2-4 a e hoʻoponopono pono i kēia ʻano.

No ka hypercholesterolemia mua a hoʻohui ʻia (kāwili ʻia) hyperlipidemia no ka hapanui o nā maʻi, ʻo ka nui o Liprimar e 10 mg hoʻokahi i ka lā. Hōʻike ʻia ka hopena therapeutic i loko o 2 mau pule a hiki i ka lōʻihi ma waena o 4 mau pule. Me ka lōʻihi o ka mālama ʻana, hoʻomau ka hopena.

Me ka hypercholesterolemia famerial homozygous, ua kauoha ʻia ka lāʻau lapaʻau ma loko o kahi pānaʻi o 80 mg hoʻokahi i ka lā. (ka hoʻemi ma ka pae o LDL-C e ka 18-45%).

I ka hihia o ka huni o ka ate, pono e hoʻemi ʻia ka nui o ka liprimar ma lalo o ka kaohi mau o ka hana a ACT a me ALT.

ʻAʻole pili ka hana o ka renal i ka pale i ka nānā ʻana o ka atorvastatin i loko o ke kaila koko a i ʻole ka pae o ka hōʻemi i nā mea i loko o ka LDL-C i ka wā e hoʻohana ai i Liprimar, no laila, ʻaʻole i koi ʻia ka hoʻoponopono ʻana o ka lāʻau.

I ka wā e hoʻohana ai i ka lāʻau lapaʻau i nā maʻi maʻi ʻelemakule, ʻaʻohe ʻokoʻa ʻole o ka palekana, pono ka hoʻohālikelike ʻia me ka lehulehu kanaka, ʻaʻole pono ka hoʻoponopono ʻana o ka dosis.

Inā pono ka hana like me ka cyclosporine, ʻaʻole pono ka nui o ka liprimar® i ka 10 mg.

Nā manaʻo e hoʻoholo ai i ke kumu o ka mālama ʻana

A. Noha mai ka National NCEP Cholesterol Education Program, USA

* Hōʻike kekahi mau loea e hoʻohana i ka hoʻohana ʻana i nā lāʻau palaka lipid e hōʻemi ana i ka ʻike o LDL-C inā ʻaʻole ka hopena o ke ʻano ola i ka emi ʻana o kona waihona i ka pae.

ʻO nā huahana e hana nei me Rosuvastatin

"Rosuvastatin" kahi kolu o ka hanauna o ka hanauna i loaʻa ka hopena lipid. Hoʻomoe maikaʻi ʻia nā hana i hoʻokumu ʻia ma luna o ka wai o ke koko. ʻO kā lākou hopena nui ka hōʻemi ʻana i ka nui o ka kolamu a me nā lipoproteins atherogenic. ʻO kekahi ʻano maikaʻi hou, ʻo "Rosuvastatin" no ka hopena ʻole o ka hopena o ka pehu a me ka hōʻino ʻole i ka ʻōpū o ka ʻiʻo. No laila, ʻo nā statins e pili ana i ka rosuvastatin e liʻiliʻi i ka hoʻopiʻi ʻana i nā hana hoʻopiʻi i loko o ke ʻano o ka maikaʻi ole o ka ate, ka piʻi kiʻekiʻe o nā transaminases, myositis, a me myalgia.

Ke hana nei i ka hana pharmacological nui ma ke kāohi ʻana i ke kāpili a hoʻonui i ka hoʻonui ʻana i nā pupu atherogen o ka momona. Loaʻa ka hopena o ka mālama ʻana i ka mālama ʻo Atorvastatin, ʻo nā hopena mua e ʻike ʻia ma ka hopena o ka pule mua, hiki i ka hopena kūpono loa ke ʻike ʻia i nā hebedoma 3-4.

Koho ʻia nā lāʻau lapaʻau e pili ana i ka rosuvastatin:

• "Crestor" (hana o Britain Nui),
• Mertenil (hana ʻia ma Hungary),
• "Tevastor" (hana ʻia ma ʻIseraʻela).

"Crestor" a "Liprimar" i mea e koho ai? Pono ke koho ʻana e nā māka i hele.

ʻO nā huahana e pili ana nā Simvastatin

ʻO kekahi lāʻau lapaʻau lipid ʻano haʻahaʻa ʻē aʻe ʻo Simvastatin. E pili ana iā ia, ua hoʻokumu ʻia he nui o nā lāʻau lapaʻau e hoʻohana pono e mālama i ka atherosclerosis. ʻO nā hoʻokolohua haukapila o kēia lāʻau lapaʻau, i mālama ʻia ma mua o ʻelima mau makahiki a e pili ana i nā mea he 20,000 o ka poʻe, ua kōkua i ka hopena e hiki i nā lāʻau lapaʻau e simvastatin e hōʻemi i ka hōʻeha ʻana i ka puʻuwai a me nā hōʻeha i nā mea maʻi e hōʻeha nei i nā puʻuwai cardiovascular a me cerebrovascular.

ʻO nā hui o Liprimar e pili ana i ka simvastatin:

• Vasilip (hana ʻia ma Slovenia),
• "Zokor" (hana - Netherlands).

ʻO kekahi o nā hoʻoholo i nā mea e pili ana i ke kūʻai ʻana i kahi lāʻau lapaʻau ka mea kumu kūʻai. Hoʻopili hou kēia i nā lāʻau lapaʻau e hoʻihoʻi i nā pilikia o nā momona o ka momona o ka momona. Hoʻolālā ʻia ka loiloi o nā maʻi like i nā mahina he nui, a i kekahi mau makahiki. ʻO nā kumukūʻai no nā lāʻau lapaʻau e like me nā hana pharmacological ʻokoʻa like me nā ʻoihana kūʻai lāʻau i nā manawa ma muli o nā ʻano kumukūʻai kumu kūʻai o kēia mau ʻoihana. ʻO ke koho ʻana i nā lāʻau lapaʻau a me ke ʻano koho ana e pono e mālama ʻia e ke kauka, eia naʻe, ke koho o ka mea maʻi i nā lāʻau lapaʻau mai kekahi ʻano lāʻau lapaʻau e ʻokoʻa, i ʻokoʻa i ka mea hana a me nā kumukūʻai.

ʻO nā lāʻau lapaʻau āpau o luna a me nā mea ʻē aʻe, ua kau ʻia ka liprimar, ua hele i nā hoʻokolohua lapaʻau a ua hoʻokau iā lākou iā lākou iho he mau ʻoihana kūpono e hoʻomaʻamaʻa i nā momona momona. Loaʻa ka hopena maikaʻi ma ke ʻano o ka hoʻohaʻahaʻa i ka cholesterol i 89% o nā mea maʻi i ka malama mua o ka mālama ʻana.

ʻO nā loiloi e pili ana iā Liprimar he maikaʻi loa. ʻO ka lāʻau lapaʻau e hōʻemi pono i ka kolamu o ke koko, pale i ka hōʻemi o ka hoʻomohala ʻana i nā hoʻopiʻi cardiovascular. ʻO nā hiʻohiʻona maikaʻiʻole - nā kumukūʻai kiʻekiʻe a me nā hopena hopena. ʻO nā mea hoʻohālike a me nā kuʻuna, lehulehu e like me Atoris. Hana ia i nā liprimaru, hana maoli ʻaʻole ia i nā hopena ʻino o ke kino.

Hōʻoia ʻia nā loiloi ma waena o nā analogie ke kumu kūʻai, makemake ʻia ka Lūkini Lūkulu. ʻOiaʻiʻo, ʻoi aku ka maikaʻi o kāna hana ma mua o ka Liprimar.

ʻO nā analogs lypimar e pili ana i Simvastatin

ʻO kekahi lāʻau lapaʻau hypolipidemic kekahi simvastatin. Hoʻohana ʻia i ka lāʻau lapaʻau no kahi manawa lōʻihi, e pili ana i ka hanauna kahiko o nā statins. Ua hōʻoia ka noiʻi haukaʻi i kona pono i ka pale ʻana o nā hōʻeha o ka naʻau a me nā hōʻeha i nā mea maʻi me ka maʻi cardiovascular.

ʻO nā lāʻau lapaʻau kaulana loa:

• Vasilip (Krka, Slovenia). 28 hiki i nā papa papa o 10 mg ke kūʻai aku no 350 rubles.,
• Zokor (MSD Pharmaceuticals, ka Netherlands). 28 papa o 10 mg kumukūʻai 380 mau rubles.

Nā manaʻo no ka koho o ka lāʻau lapaʻau

Pono ke kauka e kuhikuhi ai a koho i ka lāʻau lapaʻau i kūpono no ʻoe. Akā ʻoiai ke ʻano o ke kumukūʻai o nā lāʻau lapaʻau a i kekahi manawa nui ia, hiki i ka mea maʻi ke hoʻoponopono kūʻokoʻa i kēia koho, nānā i ka hui pharmacological i pili i ka lāʻau lapaʻau i kauoha ʻia: atorvastatin, rosuvastatin a simvastatin.

ʻO ia, inā ua kuhikuhi ʻia ʻoe i nā papa e pili ana i ka atorvastatin, hiki iā ʻoe ke koho pono i kahi analog e pili ana i kēia mea.

ʻO Liprimar, nā loiloi o ka hōʻona maikaʻi loa mai ka ʻaoʻao o nā mea maʻi a mai ka ʻaoʻao o nā kauka, ke koho maikaʻi loa no ka hōʻemi ʻana o ka pae ʻana i ka pae o ka "maikaʻi" kolamu i ke koko, no ka mea he maʻi lapaʻau maoli kēia a me ka hōʻoia ʻia.

E hilinaʻi i nā lāʻau lapaʻau i loiloi a hōʻoia i ka hana. Ke lawe nei i kēlā mau kālā, aneane 90% o nā maʻi e loaʻa i ka emi ʻana o ka cholesterol i loko o nā hebedoma 3-4 mua o ka hoʻokele ʻana.

Hōʻailona Liprimar

He lāʻau lapa-lipidahi kēia, aia i ka atorvastatin hoʻoikaika hoʻoikaika. Kuhi puka - nā papa. Kēia huapalapala i hōʻike ʻia e nā lipid-hoʻohaʻahaʻa a me nā hypocholesterolemic waiwai. I lalo o ka mana o ka waiwai hana nui.

• ka nui o nā lipoproteins haʻahaʻa haʻahaʻa i loko o ke koko i emi iho ai,
• ka emi o ka neʻe ʻana o ka triglycerides,
• hoʻonui ka nui o nā lipoproteins density kiʻekiʻe.

Hoʻololi ka lāʻau lapaʻau i kāna kolamu a me kāna hana ʻana i ka ate. Hāʻawi kēia iā ʻoe e kuhikuhi i ka lāʻau lapaʻau no nā ʻano ʻano ʻili o ka dyslipidemia, hoʻoilina a loaʻa ka hypercholesterolemia, a pēlā aku i ʻike ʻia me ka ʻano homozygous o ka hypercholesterolemia. Eia kekahi, ua hoʻohana ʻia kēia mea hana e mālama ai i ka pectoris angina a me nā pilikia ʻē aʻe o ka ʻōnaehana cardiovascular, ma laila e hōʻemi ai i ka hōʻalo o nā hōʻeha.

Nā hōʻailona no ka hoʻohana ʻana:

• hypercholesterolemia maʻamau,
• endogenous familial hypertriglyceridemia,
• dysbetalipoproteinemia,
• huiʻāina hyperlipidemia.

Me ke ala o ka pale ʻana i nā maʻi o ka ʻōnaehana cardiovascular:

• nā mea maʻi e pilikia ana no ka hoʻomohala ʻana i ka maʻi puʻuwai a me nā maʻi vascular,
• me ka angina pectoris, e pale ai i ka hoʻomohala ʻana o nā huaʻeha, nā hōʻeha, ka puʻuwai o ka naʻau.

Pākuʻi ʻia nā maʻi:

• hapai
• umauma umauma,
• maʻi maʻi hōʻola
• hypersensitivity i nā ʻāpana o ka huahana,
• glucose-galactose malabsorption,
• congole lactase kakali,
• hoʻohana me ka waikawa fusidic,
• makahiki i 18 makahiki.

Hoʻomaka pinepine, lawe ʻo Liprimar i ka ulu ʻana o ka hana ʻino kino e kū mai ana i kahi ʻano ʻano maʻalahi a pehu.

• hōʻeha, hōʻeha, hoʻomanaʻo a hoʻoweliweli, ʻoluʻolu, hypesthesia, paresthesia,
• manaʻo ʻino
• ka hiʻohiʻona o ka "pale" ma mua o nā maka, ʻike maka ʻole.
• tinnitus, luhi loa - lohe ʻia,
• koko mai ka ihu, ʻehaʻeha,
• nā huakini, ka nausea, paʻakikī ka hoʻowalewale ʻana, ke kīwī, nā ʻōpū ma ka ʻōpū, ka nāʻi ʻana o ka pancreas, belching,
• hepatitis, cholestasis, renal gagal,
• ʻōhumu, ʻōpū, kau i ka ʻili o ka ʻili, urticaria, Lyell syndrome, angioedema,
• ʻeha a me ke ʻeha hoʻi, hui pū, ka hōʻeha o ka ʻāʻī, ke ʻeha o ke kuʻekuʻe, ʻeha ʻeha, myopathy,
• huakai
• maʻi pāhoihoi, pehu anaphylactic,
• hyperglycemia, anorexia, kaupaona momona, hypoglycemia, maʻi mellitus,
• thrombocytopenia
• nasopharyngitis,
• keokeo, ka ʻoha, huehue, ʻeha ma ka umauma.

Ke alakaʻi nei ka hoʻohana ʻana iā Liprimar i ka hiʻohiʻona o: ka ʻeha, ka ʻōpū, ka hoʻomanaʻo ʻana a me ka ʻono ʻana o ka naʻau, hypesthesia, paresthesia.

Ma mua o ke kuhikuhi ʻana i ka mālama ʻana me kēia lāʻau lapaʻau, ʻike ke kauka i ke pae o ka cholesterol i ke koko, a laila kuhikuhi iā i ka hana kino a me ka ʻai. Hoʻomaopopo ka hopena therapeutic o ka lawe ʻana i ka lāʻau ma hope o 2 mau pule. I ka hihia o ka hana o KFK i nā ʻoi aʻe o 10 mau manawa, ua hoʻokuʻu ʻia ka mālama ʻana me ka Liprimar.

Poke? I? O man?

ʻO ka mea hana iā Atorvastatin ʻo Atoll LLC (Lūkini), Liprimara - PFIZER MANUFACTURING DEUTSCHLAND GmbH (Kelemānia). Loaʻa nā papa o Atorvastatin i ka pale o ka pale, kahi e hoʻemi ana i ka hopena o nā hopena maikaʻiʻole mai ka gastrointestinal tract. ʻAʻohe o ka pāpale liprimar o kēia ʻano pale, no laila ʻaʻole palekana lākou.

Nā Hōʻike Hoʻomaʻi

ʻO Tamara, 55 makahiki, ʻo Moscow: "I hoʻokahi makahiki i hala aku nei ua hana ʻia kahi hōʻike kino, a hōʻike ʻia nā hoʻokolohua he nui koʻu kolamu i loko o koʻu koko. Ua kuhikuhi aku ka palaloli iā Liprimar. Ua hōʻole aku ʻo ia i ke ʻano o ka mālama ʻana, ʻoiai ua makaʻu ʻo ia i ka hoʻoulu ʻana ʻana i nā ʻano maikaʻi ʻole o ke kino. Ma hope o 6 mau mahina i lilo au i kahi hōʻike lua, ka mea i hōʻike i ka cholesterol ke ʻano maʻamau. "

Dmitry, 64 makahiki o Tver: "Ua loaʻa au i ka maʻi diabetes a me nā maʻi maʻi coronary. Ua ʻōlelo aku ke kauka i kahi cholesterol hoʻemi ʻana i ka meaʻai, i ka manawa e pono ai e lawe i ka lāʻau lapaʻau Atorvastatin. Ua inu au i ka 1 papa 1 i ka manawa. Ma hope o 4 mau pule ua lilo ʻo ia i nā hoʻokolohua - he maʻi maʻamau ka cholesterol. ”

Ka hiʻohiʻona o ka lāʻau Liprimar

ʻO ia ka lāʻau, ʻo ka hopena nui o ka hopena ka hoʻohaʻahaʻa ʻana i nā momona koko a me ka kolamu. ^ E Ha yM. Me ia, hana ka normalization o ka puʻuwai, e hoʻomaikaʻi ka nui o nā moku, a ke emi ʻana ka pilikia o ka hoʻomohala ʻana i nā maʻi maʻi.

Hoʻokaʻawale ʻia nā hōʻailona ma lalo nei no ka hoʻohana ʻana:

• ʻO ke hoʻonui maʻamau i loko o ka cholesterol.
• ʻO nā momona momona.
• Hōʻino ka hana o ka lipid metabolism.
• Hoʻonui kahoila triglyceride.
• Nā hōʻailona o ka maʻi puʻukū coronary.
• ʻO ka paleʻana i nā pilikia cardiovascular.

1. Hypersensitivity i nā ʻāpana.
2. ʻO ka hana hema ʻole.
3. ʻO ka hepatitis o ke ʻano o ka wī.
4. Kataract ka maka.
5. ʻO ka hana e hoʻonui ai i nā pōkole enima.
6. ʻLelo ʻia a me ka wā o ka umauma.

ʻO ka maʻamau, ʻaeʻoluʻolu kēia lāʻau lapaʻau me ka ʻole e hoʻopalike. Akā i nā hihia līlū, nā hopena i makemake ʻole ʻia mai nā kūwili ʻana, nalo a me nā pūnaehana musculoskeletal, hiki mai nā maʻi like ʻole.
ʻO ka paona loa ma hope o ka hoʻokele ʻana e loaʻa i kekahi mau hola. ʻO ka mea ika e hoʻōla ai ʻo ka paʻakai paʻakai. Loaʻa nā mea hou i ka calcium carbonate, milkweed wax, E468 aditif, cellulose, lactose a me nā mea hou aku.

ʻO nā mea like o nā kālā kālā

ʻO nā lāʻau lapaʻau i nīnau ʻia nā kikowaena kūloko o kēlā me kēia. ^ E Ha yM. Loaʻa ka maikaʻi o nā maʻi a nā mea maikaʻi loa. Hoʻopili pū lākou i ka waihona hoʻōla pono, a no laila e loaʻa kahi hopena therapeutic like. Loaʻa nā ʻaoʻao ʻelua i ka hana papa. Loaʻa iā lākou nā ʻōlelo like like no ke hoʻohana, contraindications, nā hopena ʻaoʻao, ke kumu o ka hana.

Hoʻohālikelike, nā ʻokoʻa, a me nā mea e ʻoi aku ka maikaʻi ke koho

ʻAʻole ʻike nā ʻano o kēia mau lāʻau lapaʻau, no laila hiki iā lākou ke hoʻololi i kekahi i kekahi me ka ʻae ʻana me ka kauka hele mai.

ʻO kekahi o nāʻokoʻa ka ʻāina kumu. ʻO Liprimar ka lāʻau mua loa o ka hana ʻana o ʻAmelika, a ʻo ka Atorvastatin ka home. I kēia mau manaʻo, heʻokoʻa nā kumukūʻai. ʻO ke kumu kūʻai o ka mea kūlohelohe he 7-8 mau manawa ma mua o nā kumukūʻai a me nā nui 700-2300 mau rubles, kumukūʻai kumukūʻai o atorvastatin 100-600 rubles. ^ E Ha yM. No laila, i kēia hihia, ua lanakila ka lāʻau lapaʻau.

ʻOiai ka manaʻo o ia mea lako a me ka mea pono, ua manaʻo ʻia ʻo Liprimar i ʻoi aku ka maikaʻi, no ka mea he lāʻau lapaʻau mua. ʻO ka hoʻohālikelike home hale i kēia mea he haʻahaʻa loa iā ia a ke loaʻa ʻole nā ​​hopena maikaʻi aʻe i ke kino, e like me ka hōʻike ʻia e nā loiloi maʻi. Eia kekahi, ʻo Liprimar e hoʻohana me ka akahele e ka pediatrics. ʻO ia wale nō ka lāʻau lapaʻau-hoʻemi haʻahaʻa e hiki ke hoʻohana ʻia e mālama i nā keiki mai nā makahiki ʻewalu. ʻAʻole ia e like me Atorvastatin, ʻaʻole ia e pili i ka ulu o ke kino a me ke kaʻina o ka wā poperty ma nā keiki.

Hiki iā lākou ke hana ma ka mālama 'ana o nā maʻi me ka mellitus o ka maʻi mellitus o ka ʻano mua a i ʻole ʻelua. Akā mai poina e hiki i kā lākou mea neʻe ke hiki ke hoʻololi i ka glucose koko, no laila pono ke mālama ʻia i ka lāʻau ma lalo o ka mākaʻikaʻi koʻikoʻi o kahi kauka. Ma muli o ke kumuʻoiaʻiʻo nā papa Atorvastatin i ulana ʻia ke kiʻi, e pono ke koho i kēia ʻano mea no ka poʻe me kēia ʻano pili. ʻO ka hōʻemi ʻana i ka pale i ka hopena o kekahi hopena maikaʻi ʻole.

Nā hana hana i ka hana

Hoʻopili i nā kolamu, ʻo ka nui o nā pūmua-momona momona me ka haʻahaʻa haʻahaʻa (LDL) he weliweli hoʻi i ka ʻōnaehana cardiovascular. Noho lākou ma ka paia o nā kīʻaha koko, e hana ana i nā huaʻa i kapa ʻia ʻo colesterol. A ʻo kahi hopena, ke ulu ʻana o ka atherosclerosis - kahi maʻi kahi e emi ai ka lumen o nā moku koko, ua luku ʻia ko lākou mau pā. Hoʻopiha kēia kūlana me nā hemorrhages (nā hōʻeha), no laila pono pono e kāohi i ka nui o ka kolamu "hewa".

Atorvastatin i nā lāʻau ʻelua ma hope o ka hoʻokō e komo i ke kahe koko a me nā puʻuwai. I ka hihia mua, hoʻopau wale ia i nā moʻo maikaʻi ʻole. A i loko o ke aniani, kahi e ulu ai ka hoʻouluʻana o ka cholesterol, ua komo ka lāʻau lapaʻau i kēia hana a hoʻoliʻi i ia. Pono e lawe ʻia ʻo Atorvastatin a me Liprimar i nā wā i kūleʻa ʻole ai nā meaʻai a me nā haʻuki (me nā hua ʻāina o ka hypercholesterolemia).

Hoʻomaopopo ʻia ʻo Atorvastatin a me Liprimar no nā hōʻailona like:

• ʻōpiopio hypercholisterinemia o nā ʻano like ʻole, ʻaʻole ʻae ʻia e ka mālama ʻana e ka ʻai a me ke hoʻonaʻauao kino,
• ʻO ke ʻano ma hope o ka hoʻoulu ʻana o ka puʻuwai (necrosis o kahi ʻāpana o ka naʻau ma muli o ka neʻe ʻana o ka haunaele lele)
• ka maʻi ʻōpū coronary - hoʻopōʻino i kāna mau musots mau a me ka haunaele ma muli o ke kahe koko,
• ʻo ka angina pectoris he ʻano maʻi ma mua o ka ʻōpū o ka ʻehaʻeha,
• maʻi mellitus maʻiʻi
• ke koko kiʻekiʻe (hypertension),
• atherosclerosis.

E hoʻokuʻu i nā palapala a me ke kumukūʻai

Mea kūʻai ʻia ʻo Atorvastatin o ka hana hale i nā lāʻau kūʻai. Hoʻouka ʻia ka lāʻau lāʻau e nā ʻoihana kūʻai lapaʻau e wehewehe i ka nui o nā kumukūʻai no ia. Hoʻopilikia ka uku i ka helu o nā papa i hoʻokomo i loko o ka peke a me ka make ʻana o ka mea ikaika:

• 10 mg i ka 30, 60 a me 90 pcs. i loko o kahi pā - 141, 240 a 486 mau rubles. ia wa
• 20 mg i 30, 60 a 90 mau pcs. - 124, 268 a me 755 mau rubles,
• 40 mg, 30 pcs. - mai 249 a 442 mau rubles.

ʻO Liprimar kahi papa enteric-soluble o ka hui ʻAmelika ʻo Pfizer. Kuhi ʻia ke kumu o ka lāʻau lapaʻau e like me kāna maʻi a me ka nui.

• 10 mg, 30 a 100 mau ʻāpana i kahi pā - 737 a me 1747 mau rubles,.
• 20 mg, 30 a 100 mau pcs. - 1056 a 2537 mau rubles,
• 40 mg, 30 papa - 1110 rubles.,
• 80 mg, 30 mau papa - 1233 nā rubles.