Atorvastatin C3
- Mālama i nā pae o ke kō no ka lōʻihi
- Hoʻihoʻi hou i ka hana insulin pancreatic
Ua hoʻohana maikaʻi kā mākou poʻe heluhelu iā Aterol e hoʻohaʻahaʻa i ka cholesterol. Ke ʻike nei i ka kaulana o kēia huahana, ua hoʻoholo mākou e hāʻawi iā i kou makemake.
ʻO ka pilikia o ke kolamu koko nui i ke koko i kēia lā ke alo i ka lehulehu. Mālama ʻo nā Therapist a me nā cardiologists i kēia hōʻailona me ka mālama kūikawā, no ka mea e kamaʻilio e pili ana i ke ʻano o ke kau ʻana o nā moku, ko lākou patene, a me ko lākou hiki ke hoʻopaʻa ʻia.
Hoʻohālikelike i nā pae kolamu me ka lāʻau lapaʻau. ʻO ka maʻamau, maikaʻi ka Atorvastatin i kēia. Pono ʻoe e lawe ia ma hope o ke kamaʻilio ʻana i ke kauka a hana i kahi hoʻokolohua kūpono, ʻo ia ka mea e hōʻoia ai i ka loaʻa ʻana o nā hōʻailona me ka ʻae ʻana iā ʻoe iho i kahi maʻi.
Aia kēia lāʻau lāʻau i ka papa lāʻau o ka pharmacological o nā statins, i mea e kōkua i ka pani ʻana i ka holomua o nā palaki kolesterol ma nā paia o nā kīʻaha koko. I ka manawa like, ka like o ka wahi o nā wahi i loaʻa i ka moku ma hope o ka mālama ʻana. ʻO nā mea i loko o ka lāʻau lapaʻau e hiki ke hoʻolōʻihi i ka holomua o ka maʻi naʻau coronary, ka ʻōpū o ka pono o nā wāwae a me nā maʻi cerebrovascular.
E hele maikaʻi loa ʻo Atorvastatin, akā hiki i ka meaʻai ke hoʻopilikia iki i kēia hōʻailona, ʻoiai inā ʻaʻole ka loli o ka LDL i ke koko.
He aha ka hapa o kēia lāʻau lapaʻau? ʻO ke kalaiwa trihydrate kahi hana ikaika o ka lāʻau lapaʻau, a me nā mea ʻē aʻe e pili ana:
- cellulose
- kalaka
- silika
- titanium
- macrogol.
Hiki ke kūʻai lilo i ka lāʻau ma loko o kahi inane o 10, 20, 40 a me 80 milligrams.
I mea e ʻike ai i ka hopena o ka hoʻohana ʻana, pono ʻoe e inu maʻamau i nā papa no ʻelua pule me kahi hala ʻole. Ma hope o hoʻokahi mahina, he hopena ʻoi paha ka hopena o ka hoʻokipa e mālama ʻia, i mālama ʻia ma ka papa like i ka manawa o ka papa holoʻokoʻa o ka mālama ʻana.
Nā ʻōkuhi no ka hoʻohana ʻana i ka lāʻau lapaʻau
ʻO ke kūpono e pili ana i ka mālama ʻana i ka atherosclerosis a me ke kolamu kiʻekiʻe koko. No laila, ua manaʻo ʻia ʻo atorvastatin e lawe pū i ka manawa like me ka makaʻala ʻana i ka ʻai anticholesterol, i mea e hoʻomau i ka holomua o ka maʻi.
Hiki iā ʻoe ke lawe i ka lāʻau lapaʻau me ka ʻole e pili ana i ka kau ʻana i ka meaʻai, ʻo ia hoʻi, i kēlā me kēia manawa kūpono no kahi kanaka. Kuhi ʻia ka dosage i ka poʻe i hele i ke kauka ma ke kumu o nā hoʻopili. I ka papa holoʻokoʻa, pono e nānā ʻia nā pae kolamu plasma, a, e pili ana i kēia, inā pono, e hoʻoponopono i ka nui a me ka lōʻihi o ka mālama ʻana ma hope o ʻelua a ʻehā pule.
Hoʻomaka ka Therapy i nā 10 milligrams o ka waiwai, pono e lawe ia i hoʻokahi lā i ka lā. A laila hiki ke loli ka nui o nā lāʻau lapaʻau ma waena o 10-80 milligrams i kēlā me kēia lā. Inā hoʻohālikelike ʻia ka lāʻau lapaʻau i hui pū me Cyclosporine, a laila ʻaʻole hiki ke nui ke nui iā Atorvastatin ma mua o 10 milligrams.
Inā pili ka lāʻau i ka lāʻau e pili ana i ka hoʻomohala ʻana i ka hypercholesterolemia familial a homozygous, a laila pono ka paʻakai i ka 80 mg i kēlā me kēia lā. Pono e māhele ʻia kēia kumukūʻai i ʻehā mau noi o 20 milligrams i kēlā me kēia. ʻO nā maʻi me ka pilikia ʻole e pono ai e hoʻoponopono i ke ʻano o ka lāʻau lapaʻau, ʻaʻole like i nā mea maʻi me ka hiki ʻole o ka ate.
Inā he overdose o ka lāʻau a i ʻole allergy e hele, e kipa koke ʻoe i ke kauka e kuhikuhi i ka mālama maʻi.
Nā hōʻailona a me nā contraindications no ke hoʻohana
Ke koho ʻana i kahi lāʻau lapaʻau, hiki i nā hanana contraindications ke hoʻohana i ka lāʻau lapaʻau ka mea e noʻonoʻo ai.
Ke papa ʻāpono hana i ka lāʻau.
ʻO ka wā koho e pono ai e ke kauka hele ʻana, me ka mālama ʻana i nā contraindications a me nā ʻano o ke kino o ka mea maʻi.
No ke aha e kuhikuhi pinepine ʻia ai ʻo Atorvastatin?
Hōʻikeʻia kēia lāʻau lapaʻau:
- Me ka cholesterol kiʻekiʻe.
- Me nā ala e pili ana i nā kīʻaha koko a me ka puʻuwai (ʻoiai inā ʻaʻole i ʻike ʻia kēia mau maʻi, akā aia nō nā mea like ʻole e like me ke koʻikoʻi, maʻi, ka maʻi maʻi, ke ʻano kiʻekiʻe, hypertension, a me ka predisposition hoʻoilina).
- Ma hope o ka mea maʻi ua hōʻeha i ka ʻeha, hōʻeha nā puʻuwai, a maʻi i ka pectoris angina.
E like me ka mea i ʻōlelo ʻia ma mua, pono e hui pū ʻia ka mālama ʻana me Atorvastatin me kahi meaʻai.
E like me nā lāʻau lapaʻau, aia kēia lāʻau lapaʻau i kekahi mau contraindications no ke hoʻohana.
ʻO kēlā mau contraindications nā:
- nā mālamalama maikaʻi ʻole
- maʻi kūlohelohe maʻi,
- hapai a me ka lactation manawa,
- makahiki ʻewalu,
- ke aloha ʻole i nā mea o ka lāʻau lapaʻau, e pili ana i ka mea hiki i kahi alerio ke hele mai.
ʻAʻole pono e lawe ʻia ʻo Atorvastatin e nā keiki, me nā ʻōpio hoʻi ma lalo o ka nui o ka makahiki o ka hapa nui, ma muli o ka palekana o ka hoʻohana a me ka hopena o ka mālama ʻana me kēia lāʻau lapaʻau i nā keiki liʻiliʻi ʻaʻole i hoʻopaʻa pono ʻia.
ʻAʻole maopopo ia paha inā hiki i ke lāʻau lapaʻau ke hoʻopuka ʻia ma ka umauma umauma. Eia naʻe, i ka noʻonoʻo ʻana i ka hopena o nā hanana ʻino i nā pēpē, i ka wā e hōʻike ʻia ai ka hoʻohana ʻana i ka lāʻau lapaʻau no nā wahine i ka wā e hānai ai, pono e haʻalele i ka ʻōpū.
No nā wahine i mālama i ka wā o ko lākou hānau ʻana, pono lākou e hoʻohana i ka ʻokiʻoki i ka wā o ka hāpai ʻana.
Ma keʻano holoʻokoʻa, ua ʻāpono ʻia ke koho ʻana o Atorvastatin i kēia wā ke hele a loaʻa kahi liʻiliʻi haʻahaʻa o ka hapai ʻana, a ke ʻike nei ka wahine i ka hopena o ka hopena no ka mālama ʻana i ka maʻi hānau.
ʻO nā hopena ʻaoʻao o ka hoʻohana ʻana i ka huahana
E like me ka hapa nui o nā lāʻau lapaʻau, he nui ka hopena o ka atorvastatin i ka wā e hoʻohana ʻia ai i ke kaʻina hana.
Pono e noʻonoʻo ʻia ka hopena o nā hopena ʻaoʻao i ka wā e lawe ai i ka lāʻau lapaʻau.
I mea e pale ai i nā hopena maikaʻi ʻole o ke kino, pono ke kuhikuhi a ka lāʻau lapaʻau e kāu kauka wale nō.
ʻO ka hoʻohana ʻana i ka lāʻau Atorvastatin hiki i nā hopena ʻaoʻao.
- ʻāʻī, hoʻohuihui, ʻūhā a me ke kīhāpai ʻana.
- nā hopena kūlohelohe
- thrombocytopenia, anemia,
- rhinitis a me bronchitis,
- ʻO nā maʻi ʻalapihi, a me ke kō ʻana hoʻi,
- hoʻonui nui loa
- māhule
- ke ʻano o ka ulu ʻana o ka mālamalama i ka mālamalama,
- nā maka maloʻo, ke kaumaha hemorrhage,
- tinnitus, ʻeha a me ka ʻōpū,
- ʻōpala
- seborrhea, eczema,
- hoʻonui hoʻonui ʻia
- ʻeha a ʻū ma luna o ka ʻili,
- ho'ēmi ʻia libido i ka wahine, ʻeuʻeu lewa a me ka make ʻole i nā kāne,
- myalgia, ʻehaʻuwā, kani kaʻe ʻana o ka ʻōpū.
Hoʻopili pū me nā lāʻau ʻē aʻe
ʻAʻole kuhikuhi ʻia e hoʻohana i ka lāʻau lapaʻau i ka manawa like me:
- ʻO ka lāʻau antifungal.
- Nā papa hana maʻi, antibiotics.
- Cyclosporine.
- Kūkū hua o ka waila fibroic.
Me kēia hui pū kekahi o nā lāʻau lapaʻau, ke piʻi nei ka nui o ka neʻe o ka Atorvastatin a me ka nui o ka piʻi ʻana o ka myalgia.
ʻO ka hoʻohanaʻana i nā hana hoʻokō, e hoʻopili ana i ka alumini a me ka magnesium, hiki ke kōkua i ka hoʻēmi ʻana o ka hōʻemi o ka lāʻau. Akā ʻaʻole lākou e pili i ka helu o ka emi ʻana o ka nui o ka cholesterol a me LDL.
Me ka nui o ka makaʻala, pono kekahi e mālama i ka hui ʻana o Atorvastatin me nā lāʻau lapaʻau e hōʻemi ana i ka neʻe ʻana o nā testosterone steroid (no ka laʻana, ʻo Ketoconazole a i Spironolactone).
Nā ʻōlelo kikoʻī hou aku no ka hoʻohana ʻana
Ma mua o ka lawe ʻana i ka Atorvastatin, ua kuhikuhi ʻia e hoʻokō ʻoe i nā pae kolene maʻamau ma ka hoʻololi ʻana i kou ʻano o ke ʻano a me ka hoʻoponopono ʻana i ka ʻai. ʻO kēia mau ala pilikino i pale ʻole a mālama i nā kīʻaha koko a me nā maʻi ʻē aʻe o nā kino.
Ke lawe nei i ka lāʻau lapaʻau, ʻike ʻia nā myopathies - nāwaliwali a me ka hōʻeha ʻana i nā ʻōpū o ke kino. Ma kahi o ka kānalua o kēia maʻi, pono e hoʻopau koke ka hoʻohana ʻana i ka lāʻau. Eia kekahi, hoʻonui paha i ka pilikia o ka hoʻomohala ʻana i kēia pathology me ka hoʻohana pinepine ʻana o Atorvastatin me Erythromycin, Cyclosporine, nā antifungal a me nā aʻala nicotinic.
Ke lawe nei i ka lāʻau lapaʻau, pono ʻoe e akahele i ka wā e hana ana i nā hana e pono ai ka nui o ka makaʻala, a me ke kaʻa ʻana i nā kaʻa.
ʻAʻole kōkua ʻia e lawe i nā statins a me nā mea inu wai, no ka mea hiki ke hoʻololi i ka hopena o ka lāʻau lapaʻau a i ʻole he hopena hopena.
Nā hōʻikeʻike o ke ʻano lāʻau
ʻO nā lāʻau lapaʻau e loaʻa i nā ʻano mea like a me ka hopena i ke kino, a hiki ke kuhikuhi ʻia ma ke ʻano o Atorvastatin (analogues), me Atoris, Tulip, Lipoford, Ator, Torvakard, Lipramar, Rosulip a me Liptonorm.
Pehea lākou e ʻokoʻa? Inā hana ʻoe i nā hoʻohālikelike, hiki iā ʻoe ke ʻike i ka pae maoli o nā ʻokoʻaʻehā wale nō e ka ʻāina i hana i ka lāʻau a me ka mea hana. ʻO nā lāʻau lapaʻau a pau me nā mea like like o nā mea like (ʻo nā mea i kapa ʻia he generics) loaʻa nā inoa like ʻole, e hiki ai ke hoʻomālamalama iā lākou. ʻOiai no ka mea ʻole o ka ʻokoʻa i nā mea ikaika, hiki ke noʻonoʻo ʻia kēia mau lāʻau lapaʻau i hoʻohālikelike ʻia no ka Atorvastatin.
I ka wā e mālama ai, pono e mālama ʻia ʻo Atorvastatin i kahi wahi neoneo e komo ai nā keiki, a ʻaʻole hāʻule ka lā. He mea nui ʻaʻole eʻoi aʻe ka kiʻekiʻe o ka mahana ma mua o 25 degere Celsius.
Ke hoʻohālikelike ʻia ke kumukūʻai o ka lāʻau lapaʻau hoʻokahi e kēlā me kēia hui lāʻau lapaʻau. Ka uku kumukūʻai o ka lāʻau lapaʻau ma ka nui o nā papa he 30.
- nā papa me ke kaʻe o 10 mg - 140-250 rubles,
- papa me kahi kaʻe o 20 mg - 220-390 rubles,
- nā papa me kahi kaila o 40 mg - 170-610 mau rubles.
ʻO ka kumukūʻai o ka lāʻau lapaʻau hoʻi hilinaʻi nui ʻia i ka wahi o ke kūʻai aku.
Wahi a nā poʻe maʻi e hoʻohana i kēia lāʻau lapaʻau, he hopena maikaʻi loa ia a ua kōkua i ka wikiwiki o ka hoʻokele ʻana o ka cholesterol i loko o ke kino.
Hoʻākāka ʻia ʻo Atorvastatin i kahi wikiō ma kēia atikala.
- Mālama i nā pae o ke kō no ka lōʻihi
- Hoʻihoʻi hou i ka hana insulin pancreatic
ʻO ka hopena therapeutic o ka lāʻau
Kōkua ke Atorvastatin S3 kōkua i ka hōʻemi o ke kolamu koko. Ke hoʻohana nei i ka lāʻau lapaʻau, ka hopena o ka mea maʻi i loaʻa i nā alaʻala o ka ʻaoʻao o ka ʻōnaehana cardiovascular.
ʻO ka lāʻau lapaʻau e hōʻemi i nā hōʻemi o nā hoʻopiʻi o ka atherosclerosis ma ke alo o nā mea hoʻonāukiuki ʻia:
- hiʻona kiʻekiʻe
- ka nui o nā hoʻohui nikotine,
- haʻi maʻi
- kōpili koko nui.
ʻO ka lāʻau Atorvastatin SZ ke kōkua i ka hōʻemi o ke kahe koko. Hoʻonui ia i ke ʻano o ka ʻōnaehana hematopoietic, ālai i ka hoʻokaʻawale ʻana o nā plak atherosclerotic.
Hoʻomukale ʻOihana
Hoʻololi ʻia ka lāʻau i kēlā me kēia lā i ka lā mai 10 a 80 mg. ʻO ka lāʻau ʻona e inu i hoʻokahi manawa i ka lā.
No ka hypercholesterolemia mua a me ka hyperlipidemia hui pū, ʻo ka laila i koho ʻia i kēlā me kēia lā he 10 mg. Inā loaʻa ka mea maʻi i ka hypercholesterolemia homozygous familial, koho ʻia ka pakano mua i kēlā me kēia: i ka ʻano o ka nui o nā hōʻailona nui o ka maʻi.
I ka hihia o nā hana ʻehaʻeha, pono e hoʻomaʻamaʻa ʻia i ka wā e hoʻohana ai i ka lāʻau lapaʻau ma muli o ka emi ʻana o kona huki ʻana mai ke kino. Ma ke alo o kahi ʻano like like, pono e kāohi i ka hana o ka transaminases hepatic:
Me ka hana nui o nā transaminases hepatic, he mea hoʻi i makemake ʻia i kēlā me kēia lā i ʻōlelo ʻia i kēlā lā.
Inā maʻi ka mea maʻi, ʻaʻole pono ka hoʻoponopono ʻana. Pono ka poʻe ʻōpiopio e lawe i ka lāʻau lapaʻau e like me ke kumumanaʻo maʻamau (me ka ʻole o ka hoʻoponopono ʻana i ka palena no kēlā me kēia lā)
Nā Hoʻohui
Wahi a nā ʻōlelo kuhikuhi no ka hoʻohana ʻana, pono e haʻalele i ka hoʻohana ʻana i ka lāʻau lapaʻau i ka wā o ka kali ʻana o ke pēpē a me ka ʻōpio. ʻAʻole pono ke inu o ka lāʻau lapaʻau i ka wā o ka hoʻolālā hāpai ʻana. Ua kuhi ʻia ʻo i nā maʻi ma lalo o nā makahiki 18. ʻAʻole pono ke lawe i ka lāʻau lapaʻau me ka hypersensitivity i kāna mau māhele. Hoʻokomo ʻia ka lāʻau i ka hihia o ka intolerance lactose, nā malabsorption glucose-galactose.
Hoʻohana ʻia ka lāʻau lapaʻau me ka akahele i mua o nā ala i hala:
- haehae maʻi
- epilepsy
- maʻi mellitus maʻiʻi
- alahele o nā ʻōnaehana o ka io,
- ka haʻalele ʻana o ke kaulike wai-electrolyte.
Nā hopena hopena
Ke hoʻohana nei i ka lāʻau lapaʻau, hiki i nā hopena hopena mai ka ʻōnaehana o ka lāe:
- poʻomanaʻo
- āhāhuʻe
- hiamoe hiamoe
- ka hopena o ka maʻi asthenic,
- aloha
- maʻi pālahalaha peripheral.
Ke hoʻohana ʻia nā lāʻau lapaʻau, hiki ke ʻike ʻia nā hopena kūpono:
- tinnitus
- palpela puʻuwai,
- koko koko kiʻekiʻe
- ireliaia,
- Nā ʻōpiopio
- thrombocytopenia
- ninini
- he ʻano hūnā
- ʻeha i ka ʻōpū,
- i ka pili ʻana i ka ʻono ʻana,
- ka hoemi ana o ka moe kolohe,
- ke hiʻohiʻona o ka ʻāʻī i nā kihi,
- wahī ʻaʻe
- pūpū hema
- lauoho lauoho
- kaʻiliʻili
- peripheral edema,
- ua ʻeha ka ʻōpū
- lethargy
- pale ma mua o nā maka
- nā hoʻomanaʻo hoʻomanaʻo
- hoʻonui mahuahua o ka hemoglobin glycosylated.
Nā hiʻohiʻona o ka launa pū me nā lāʻau lapaʻau ʻē aʻe
ʻAʻole ʻAi ʻia ʻo Atorvastatin SZ e hoʻohana pū me ka hana ʻole iā Varvarin. ʻO ka lāʻau lapaʻau i hoʻolālā ʻia e hōʻemi i ka cholesterol ma ke kino e hoʻopili maikaʻi ʻole ʻia me nā ʻaihua penei:
- nā huakaʻi i hāʻawi ʻia me kahi hopena antifungal,
- macrolide antibiotics,
- ʻo ia ka hopena me ka hopena immunosuppressive.
Ke hoʻohana nei i nā antacids i hoʻolālā ʻia e hoʻokaʻawale i ka wai hydrochloric, e emi iho ka paukū plasma o ka hana ikaika o ka lāʻau. Inā pono e hoʻohana i kēlā mau lāʻau like i ka manawa like me Atorvastatin SZ, ʻo ka hoʻoholo e hoʻonui ai i ka nui o nā lāʻau lapaʻau i hoʻoiho ʻia e lipid.
ʻO ʻekolu mau makahiki ke ola o ka pale o ka lāʻau. Pono ke mālama i ka lāʻau lapaʻau ma kahi e pale ʻia mai ka lā maka. ʻO ka mahana kiʻekiʻe no ka mālama ʻana i ka lāʻau lapaʻau he 25 tikelika.
Mai ka hopena o ka lāʻau lapaʻau he hopena hypolipidemic, uaʻike nā loiloi e pili ana i ka hoʻohana ʻana. Lawe lāʻau pinepine ʻia ka lāʻau me ka hoʻonui o ka cholesterol koko, i hele pū ʻia me ka angina pectoris.
I ka manawa like, loaʻa ka papa inoa o nā hopena ʻaoʻao i ka wā e hoʻohana ai ʻo Atorvastatin SZ, kiʻekiʻe loa. ʻO kēia ma muli o nā loiloi maikaʻi ʻole o nā maʻi.
Pehea e hoʻonui ai i ka hopena o ka lāʻau lapaʻau?
No ka hoʻonui i ka hopena therapeutic o ka lāʻau lapaʻau, pono ia e pili i ka meaʻai paʻa. ʻO kāna pahuhopu nui ka hoʻomaikaʻi ʻana i ka ʻaila lipid.
Me ka nui o ka kolamu o ka kolamu ma ke kino, pono ʻoe e kaupalena i ka ʻai ʻana o nā meaʻai i loaʻa i nā momona manu. ʻO ka papaʻai e kau ai i nā kīʻaha e hoʻolaʻa i ke kino me ka momona.
I mua o ka kolamu kiʻekiʻe, nā meaʻai e loaʻa ai ka nui o nā phytosterols. E pili ana kēia:
- hua sesame,
- huahana e loaʻa ai nā palaoa germ,
- nā hua kanu meli
- wahawa ʻia
- aila ʻaila
- avocado
- hua aila hua
ʻO ka mea ʻai ka loko o ka ʻai me nā pectin: nā hua citrus, nā huaʻoniu, nā ʻoni. Me ke kolamu koko nui, hoʻohana ʻia nā huahana aʻe e kū nei:
- kihua
- lau ʻeleʻele
- artichoke
- ʻeha
- ʻula
- pālato.
Ke hoʻohana nei i ka lāʻau lapaʻau Atorvastatin SZ, ʻoi aku ia e haʻalele i ka hoʻohana ʻana i ka puaʻa, ʻoki ʻiʻo, offal, aʻa, ʻala, sausages. ʻO nā ʻano o nā iʻa momona, nā caviar ʻulaʻula, nā huki, a me nā iʻa i pau a hāʻule i lalo o ka pāpā.
Noea ʻia ʻole e haʻalele i ka meaʻai i nā kīʻaha i hōʻike ʻia ma ka papa inoa.
- wōwī palaoa
- ʻōpala hāmama
- ʻōpole
- pīpī kekeʻa momona
- ʻōmole ʻona
- hau kalima
- Nā huahana Chocolate
- palm palm,
- ʻona
- ketchup.
Aia nā Atorvastatin. Hoʻohana ʻia ʻo Tulip i ka mālama ʻana i ka hyperlipidemia hui pū, ka hypercholesterolemia mua.
Ua hoʻolauna ʻia e haʻalele i ka hoʻohana o ka lāʻau me ka hypersensitivity i kāna mau māhele, ka lactose intolerance. Lā ʻia ʻo Tulip i ka wā o ka hāpai ʻana a me ka umauma. ʻAʻole ʻae ʻia ka lāʻau lapaʻau e kuhikuhi ʻia i nā mea maʻi ma lalo o nā makahiki he ʻumikumamāwalu.
Pono e hoʻohana ʻia ʻo Tulip me ka akahele me ke koko kiʻekiʻe, sepsis, ʻohi kāohi electrolyte.
Ke lawe i ka lāʻau lapaʻau, hiki mai nā hopena like ʻole.
- ʻaiaiaia
- poʻomanaʻo
- nāwaliwali koʻikoʻi
- ka hiʻohiʻona o nā ʻeha,
- enema
- ke ʻano o ka rashes ma ka ʻili,
- tinnitus
- ke ʻano o ke kaupaona keu
- hoʻemi ʻia ʻo ia iho
- ka hopena o nā hae,
- peripheral neuropathy,
- thrombocytopenia.
Hoʻololi ʻia ka ʻōhapa o nā lā o kēlā me kēia lā iā 10 i ka 10 a 80 mg. I ka hapa nui, ua kuhikuhi ʻia ka mea maʻi 10-20 mg o ka lāʻau i kēlā me kēia lā.
No Lipitor pū kekahi i ka hui o statins. E kōkua ana ka lāʻau lapaʻau e hōʻemi i ka cholesterol ma loko o nā mea maʻi i hōʻike ʻia i ka hypercholesterolemia homozygous.
Hoʻokaʻawale ʻia nā hōʻailona ma lalo nei no ka hoʻohana ʻana o Lipitor:
- hapai
- umauma umauma,
- hypersensitivity i nā māhele o ka lāʻau lapaʻau,
- ka nui o nā hana pehu kaumaha.
Hoʻohana ʻia ka Lipitor me ka akahele i mua o ka hilinaʻi i nā mea inu ʻawaʻawa, ke koko koko kiʻekiʻe, a me ka ʻike ʻole ʻana i ka electrolyte. Ke hoʻohana ʻia nei i ka lāʻau lapaʻau, ʻo nā hopena like ʻole e like me ka hōʻino ʻana, ka hōʻoluʻolu ma ka ʻōpū, ke ʻano o kahi waha maloʻo, ke poʻo, ka ʻeha, ka ʻōpū, ke kau ʻana, a me ka nui o ke koko. I kekahi mau hihia, me ka hoʻohana o Lipitor, kū mai nā ʻano hoʻopiʻi like:
- ke ea o nā puʻupuʻu i nā ʻōpū o nā wāwae,
- ka hopena o ke kaʻe koko i ka wahine,
- palpitations puʻuwai
- kulu maloo
- hoʻonui nui loa
- ka uluʻana o nā hōʻailona o ka bronchitis a i ʻole rhinitis.
I ka hopena, pono e hoʻomaopopo ʻia ka hoʻohana ʻia o ka lāʻau lapaʻau ʻaʻole wale no nā kumu pale. ʻO ka lāʻau lapaʻau ka hōʻemi o ka hopena o ka atherosclerosis ma ke alo o kahi predisposition heredary i kēia maʻi.
Ka hana lāʻau lapaʻau
Loaʻa i ka lāʻau lapaʻa ka hopena pale i ka synthesis o nā steroid a me ka cholesterol. ʻO ka pilina kumu he kumu synthetic. He paʻa paʻa mea hoʻokūkū o ka enzym HMG-CoA reductase, ka mea e hana i ke kuleana nui i ke ʻano o ka mevalonate - kahi hana e pono ai no ka hoʻokumu ʻana o ka cholesterol.
Hāʻawi ka hāmeʻa iā ʻoe e hoʻohaʻahaʻa i ka cholesterol, LDL, triglycerides i nā poʻe e hōʻeha nei i ka hypercholesterolemia famili home a i ʻole heterozygous. Hāʻawi iā iā ʻoe e hoʻonui i ke kiʻekiʻe o ka lipoproteins kiʻekiʻe, i maikaʻi no ke kino.
Hāʻawi ka hāmeʻa iā ʻoe e hoʻohaʻahaʻa i ka cholesterol, LDL, triglycerides i nā poʻe e hōʻeha nei i ka hypercholesterolemia famihial heterozygous.
ʻAʻole ke pale wale ʻo Atorvastatin i ka hana o ke kinemona i pili i ka synthesis o ka kolamu, akā kōkua pū nō hoʻi e hoʻopau i ka hope. Loaʻa kēia i ka hoʻonui ʻana i ka nui o nā receptors cellular e hoʻopaʻa ana i ka lipoproteins haʻahaʻa haʻahaʻa a hoʻolako i kā lākou hana hou kino.
Atorvastatin alakaʻi i kahi loli i ka laha o ka lipoproteins kiʻekiʻe a haʻahaʻa haʻahaʻa e ka pale ʻana i ka hana o ka papa o ka hope, kā lākou hoʻohana ʻana, a me ka hopena maikaʻi i ka pālolo iho iā lākou iho. Hoʻohana ia ka hāmeʻa i nā hihia ma kahi e lawe ai i nā lāʻau lapaʻau lipid-haʻahaʻa, ʻaʻole i emi ka pae o LDL.
Ma lalo o ka hopena o ka atorvastatin, ua hoʻemi ka nui o ke kolamu ma ka kahe wai koko i ka 50%, LDL i 60%, apolipoprotein-B i 50%, triglycerides i 30%. ʻO nā ʻikepili i loaʻa i ka wā o ka lāʻau lapaʻau ka aneane like me nā poʻe e loaʻa ana i nā ʻano hoʻoilina a me nā mea ʻole hoʻoilina o ka hypercholesterolemia, hui pū ʻia o hyperlipidemia a me nā maʻi diabetes-hilinaʻi ʻole.
Ma lalo o ka hopena o ka atorvastatin, e hoʻomaikaʻi ʻia nā waiwai o ka rheological o ke koko ma o ka hoʻemi ʻana i ka ʻike. ʻO ka emi ʻana o ka hana o ka hoʻopili ʻana o nā platelets a me kekahi mau ʻāpana o ke kaomi hoʻokalakupapa e mālama ʻia. Hoʻopilikia ka lāʻau lāʻau i ka hana o nā macrophages, pale i ka hakahaka o nā plas atherosclerotic, hiki ke loaʻa me ko lākou komo.
Ma lalo o ka hopena o ka atorvastatin, e hoʻomaikaʻi ʻia nā waiwai o ka rheological o ke koko ma o ka hoʻemi ʻana i ka ʻike.
Hiki i ka mea hana ke hōʻemi i ka hopena o ka make ma muli o ka ischemia kiko ma 15% i ka wā e lawe ai i kahi kaila o 80 mg. ʻO ka pae o ka hōʻemi o nā haʻahaʻa o nā lipoproteins haʻahaʻa haʻahaʻa i ke kahe koko e pili ana i nā pau i hoʻopau ʻia.
Lapaʻau lāʻau
Hoʻonui ikaika ka mea hana a ke kino i ka wā e lawe ʻia ai ka waha ma ke ʻano o ka mucous lamina o ka gastrointestinal tract. ʻO ka ʻike koʻikoʻi kūpono o ka hana ikaika i ka plasma e nānā ʻia ma kahi o 60-120 mau minuke ma hope o ka hoʻokele ʻana. I nā poʻe maʻi wahine, ʻo ke kumuhana o ka atorvastatin i ke kahe koko he 1/5 kiʻekiʻe ma mua o nā kāne. Hoʻohālikelike ʻia nā wai nui o ka lāʻau lapaʻau me ka ikaika ikaika, e hilinaʻi ka mea plasma i ka nui o ka lāʻau i hoʻopau.
ʻO ka huina piha o ka bioavailability o ka mea hana he 15%. Ma kahi o 30% o ka nui i lawe ʻia i ka hoʻokūkū e hōʻiliʻili i ka HMG-CoA reductase. ʻO ka pae o ka bioavailability o ka atorvastatin ma muli o nā loli metabolic i ʻike ʻia i ka waihona i loko o ka ʻōpū a me ka hepatobiliary tract. I ka wā e ʻai ai i ka meaʻai, ua hoʻemi ʻia ka wikiwiki a me ke ʻano o ka ʻike ʻana o ka mea hana.
Ke komo nei i ka plasma koko, aneane paʻa ka lāʻau i ka lawe ʻana i nā peptides. ʻO ka mea hana a me ka liʻiliʻi liʻiliʻi e komo i loko o nā membrane o nā papa koko ʻulaʻula.
ʻO ka pae o ka bioavailability o ka lāʻau e pili ana i ka hoʻololiʻana o ka metabolic i hōʻike ʻia i loko o ka mucosa ʻōpū.
I ka wā hoʻololi o ka metabolic o ka atorvastatin, ʻelua mau mea i hoʻokumu ʻia. Hoʻohālikelike ka hana o nā metabolites me nā mea hoʻomaka. Hoʻouna a 70% o ka hopena o ka lāʻau lapaʻau ma muli o ka hana o nā metabolites.
ʻO ka hoʻololi kino ʻana o ka atorvastatin i ke kaila hepatobiliary e hana ana ma lalo o ka mana o ka isoenzyme CYP3A4. ʻO ka hana ikaika o ka lāʻau lapaʻau i kekahi hiki ke pale i kāna hana.
ʻO ka wehe ʻana o ka lāʻau lapaʻau e kū nui ana me ka kahe o ka bile. ʻO ka hapalua-hapa he manawa liʻiliʻi ma luna o 12 mau hola. ʻO ka hopena therapeutic o atorvastatin e pili ana i kahi lā.
Nā hōʻailona no ka hoʻohana ʻana
Ke hōʻike nei ka hoʻohana ʻana i kēia pono mea:
- familial a non-familial hypercholesterolemia,
- hui pū ʻia
- nā maʻi e pili ana i ka helu ʻole ʻana o betalipoproteins,
- hoʻoilina ʻōpiopio.
Hoʻohana pū ʻia ʻo Atorvastatin i mea lāʻau no ka pale ʻana i nā maʻi o ka ʻōnaehana cardiovascular. Hoʻohana ʻia nō hoʻi e pale i nā hoʻopiʻi kūlohelohe i nā mea maʻi me ka maʻi naʻau coronary. Kōkua i ka hoʻemi ʻana i ka pilikia o ka make ma ka poʻe maʻi o kēia hui.
Me ka mālama pono
ʻO ka mālama koʻikoʻi i ka wā o ka hana maʻi e pono e mālama i nā mea maʻi me ka maikaʻi ʻole o ka ate. ʻO kahi contraindication pili i ka palaka, ʻo ka mea hiki i ka waiʻona hiki ke lilo i ke kumu o ka puka mai o nā ala o ka hepatobiliary tract.
ʻAʻole ʻōlelo ʻo Atorvastatin no ka poʻe me kēia mau pilikia:
- nā haunaele ma ka kaulike o nā electrolytes,
- pālahalaha
- nā maʻi hōʻea
- septicemia
- haʻahaʻa mau koko
- SD
- epilepsy
- hana i kēia manawa hou.
Pehea e lawe ai Atorvastatin C3
Lawe ʻia ka lāʻau ma ke ʻano, me ke ʻano o ka lā. Ke lawe ʻia nei ka lāʻau Atorvastatin ma hope o ka hoʻāʻo ʻana e kāohi i nā pae kolamu me ka hoʻohana ʻana i kahi meaʻai kūikawā. Inā pono ʻole ia, ma kahi o ka kaʻai ʻana o ka meaʻai, pono ka mea maʻi e lawe i kēia lāʻau.
Lawe ʻia nā papa Atorvastatin C3 i hoʻokahi lā i kēlā lā.
Ke koho nei i kahi dine i kēlā me kēia lā, ua noʻonoʻo ka nui o ka maʻi. E like me ka hiki, hiki ke 80 mg o ka lāʻau i kēlā me kēia lā. Hoʻoholo ʻia nā papa he hoʻokahi i ka lā.
Hoʻomaka pinepine ke koho o ka nui o ka dosage e hoʻomaka ʻia me ke koho ʻana i kahi palena liʻiliʻi o 10 mg. A laila, i kēlā me kēia hapalua o hoʻokahi mahina a i hoʻokahi malama paha, pono e hoʻomanawanui ka mea maʻi i kahi kikoʻī no ke kiko o nā lipids i ke kahe koko. Aia i ka hopena o ka mālamaʻana, e hoʻonui a noho paha ka nui ma luna o ka pae like.
ʻŌpala Gastrointestinal
Pane ke pane i ka lapaʻau me nā hopena maikaʻi aʻe:
- hoʻoweliwela ʻia
- ʻūlū
- eha epigastric
- hyperactivation o nā ate enzymes,
- jaundice
- pancreatic pā,
- ninini
- utuka
ʻO ka lawe ʻana i ka Atorvastatin C3 e hoʻoheʻe ai.
Mai ka ʻōnaehana musculoskeletal
- ʻāʻā naʻau
- ʻōpū paʻa
- nahoa
- ruptures tendon.
Hiki i ke Atorvastatin C3 ke hōʻeha i ka eha ʻehaʻeha.
- anaphylactic mau hiʻohiʻona,
- nā mea ʻohiʻawaʻawa.
Nā ʻōlelo kikoʻī
I ka wā hana o ka maʻi me ka atorvastatin, ua ʻike ʻia kahi hopena ma ka ʻūhā kepa. Pono kēia ʻoiaʻiʻo i ka nānā ʻana i ka pae o ka phosphokinase. Inā hele pū mai nā hōʻailona o myopathy, kāpae i ka lawe ʻana i ka lāʻau lapaʻau. Pono e kamaʻilio mua ka mea maʻi i ke kauka inā he ʻeha ma nā ʻōpū o nā ʻuhane a nā ʻūlū.
Hoʻopilikia i ka hiki ke mālama i nā mīkini
Ma ka hopena o ka hopena maikaʻi loa mai ka nūnē, pono e hoʻokaʻawale i ka manawa i hala ma hope o ka huila no nā kumu palekana.
Inā hele mai nā hopena ʻino mai ka lawelawe ʻana o ka nuku, pono e pau nā hoʻokele moku.
Ke noi no ka hana lawelawe lēʻaleʻa
Pono e mālama ʻia nā maʻi o nā mea maʻi me ka wehe ʻana o nā maʻi me ka nānā ʻana i ka pae o nā enzyme o ka ate. Mahalo i ke kiʻekiʻe o kā lākou hana, ua hoʻoponopono ʻia ke ʻano o ka lāʻau lapaʻau.
ʻAʻole nā keiki i ka lawe i ka metabolism a i ʻole excretion o ka lāʻau lapaʻau.
Hoʻopili pū me nā lāʻau ʻē aʻe
Hoʻohui like ʻole me ka phenazone e ka loli me ka loli i loko o nā waiwai ʻo pharmacokinetic o nā mea ʻelua.
ʻO ka hoʻohana pinepine ʻana o antacids i ka emi ʻana o ka ʻike o ka atorvastatin i ke kahe koko. ʻO kēia ma muli o ka hoʻopihapiha ʻole o ka mea hana ikaika.
ʻO nā lāʻau lapaʻau e hoʻonui ai i ka hana o ka isoenzyme CYP3A4 e hōʻemi i ka neʻe o kēia lāʻau lapaʻau i ka kaila koko. Hoʻomaʻamaʻa ka Rifampicin i nā hopena o ka renal, no laila, ʻaʻole i pili i ka pharmacokinetics o ka lāʻau.
ʻO ka hoʻokolohua i ka manawa o Atorvastatin a me Cyclosporine e hoʻonui i ka hopena o nā pilikia pathology.
ʻO ka hoʻohanaʻokoʻa me ka digoxin i nā hopena haʻahaʻa ʻaʻole ia e loli i ka waiwai o nā lāʻau lapaʻau. I ka nui o kēlā me kēia lā nui o ka atorvastatin, hiki ke hoʻonui ʻia ka 1/5 e pili ana i ka ʻikepili digoxin.
Hiki i ka Cyclosporine ke hoʻonui i ka ulu ʻana o nā mea ulu pono o nā ʻiʻo.
ʻAʻole i ʻike pili ʻia i loko o kahi maʻi nui me ka terfenadine.
Nā mea hoʻololi i kēia lāʻau lapaʻau.
Nā manaʻo Atorvastatin C3
Gennady Ishchenko, cardiologist, Moscow
ʻO Atorvastatin kahi lāʻau lapaʻau e hiki ai iā ʻoe ke hoʻomalu i ka pae o nā lipids i kekahi mau maʻi. Ua kuhikuhi ʻia i nā kānaka me ka hoʻonui nui ʻana i ka neʻe ʻana i ka plasma o ka cholesterol a me nā momona ʻē aʻe, a i ka poʻe maʻi i loaʻa i kēia pathology.
Hāʻawi ka mea hana no ka pale ʻana o nā hoʻopiʻi cardiovascular. I ka hui pū me ka meaʻai kūpono, hiki i nā mea maʻi ke hoʻomau i ka paona kino kūpono a alakaʻi i kahi ala maʻamau me ka hopohopo ʻole e pili ana i nā pilikia o ka naʻau.
Larisa Oleshchuk, hoʻokaumaha lāʻau, ʻo Ufa
Hāʻawi kēia mea hana i ka poʻe me ka familial endogenous hypercholesterolemia i kahi manawa no ke ola maʻamau. Ke kuhikuhi aku nei au i ka atorvastatin ʻaʻole wale nō iā lākou, akā i nā poʻe maʻi ʻē aʻe ka poʻe i loaʻa i ka nui o nā waihona kālā me nā pakanā a me nā ala āpau.
ʻAʻole wau e koi i ka kūʻai ʻana i ka lāʻau lapaʻau ma kāu māka ponoʻī. Pono ka hoʻomaʻamaʻa i ke koho kūpono o ka palena o kēlā me kēia lā a me ka nānā ʻana o ka manawa i ka pae o nā transaminases hepatic. Inā ʻaʻole e hahai, hiki i ka lāʻau lapaʻau ke alakaʻi i nā hopena pili ʻino.
Andrey, 48 makahiki, ʻo St. Petersburg
ʻO ka hopena maikaʻi. I ka hui pū me nā meaʻai kūikawā, kōkua ia e mālama i nā pae kolamu i loko o nā palena maʻamau. Lawe au ia e like me ka kauka ʻana o ke kauka, kau wau i nā hoʻokolohua a pau i ka manawa. Ma kēia manawa, ʻaʻohe ala hoʻopiʻi. Inā ʻoe e hana i nā mea āpau e like me ka mea i kākau ʻia i nā ʻōlelo aʻoaʻo, no laila ʻaʻole pilikia. Mai hoʻolaʻa pilikino. ʻO ka nānā mau ʻana e ke kauka ke kī nui i ka palekana palekana.
Elizabeth, 55 makahiki, Perm
Ua hoʻāʻo wau e lawe i ka atorvastatin. Ua lōʻihi iki ka hopena o ka maʻi ma mua o 2 hebedoma. A laila ua hoʻomaka ʻo ia e ʻike i ka nāwaliwali o nā ʻuhane, ʻike ʻia nā ʻeha. I ka wā mua ʻaʻole au i kau i kahi mea nui loa i kēia, akā i ka nui o nā ʻōuli, ua hele au i ke kauka. Hana lākou i nā hoʻokolohua kūpono a pau a hoʻokomo i ka haukapila. Kuhi ʻia e lawe i ka lāʻau lapaʻau.
No laila ʻaʻole wau i ola hou wale nō, akā nalowale hoʻi i ke koena o koʻu olakino. E makaʻala e mālama i kēia lāʻau lapaʻau a loaʻa kahi loea e nānā pololei iā ʻoe i ka wā o ka lapaʻau.
ʻO Daniel, 29 makahiki, ʻo Omsk
Hoʻopilikia wau iā ia i kahi ʻano hoʻoilina o ka hypercholesterolemia. Pono e emi ka pae o ka lipids ma ke koko. Hana wau i kēia me nā lāʻau lapaʻau e like me Atorvastatin. ʻAʻole kūʻai ʻia ka pale i ka wā e hoʻohālikelike ʻia me nā hoa ʻē aʻe, akā ʻo ka hopena ke ʻano. Hiki iaʻu ke kuhikuhi i kēia pono hana i nā poʻe a pau i loaʻa i kahi maʻi like. Inā mālama ʻia e like me nā ʻōlelo a ke kauka, hiki iā ʻoe ke ola ola piha.