Amoklav-375: nā ʻōkuhi no ka hoʻohana

375 mg a me 625 mg nāwila i ulana ʻia

Aia ma ka papa papa

mea waiwai: amoxicillin as amoxicillin trihydrate 250 mg, clavulanic acid as potassium clavulanate 125 mg (for dosage 375 mg) or amoxicillin as amoxicillin trihydrate 500 mg, clavulanic acid as potassium clavulanate 125 mg (for dosage 625 mg),

nā mea hoʻohālikelike: nā mea momona o ka silloidal, crospovidone, sodium croscarmellose, magnesium stearate, talc, cellulose microcrystalline,

ʻano hana pepa hydroxypropyl cellulose, ethyl cellulose, polysorbate, triethyl citrate, titanium dioxide (E 171), talc.

Nā papa hana, i honi ʻia me ka kiʻi ʻoniʻoni o ke keʻokeʻo a i ʻole keʻokeʻo paha, ʻano octagonal me kahi biconvex kihi, i kahakaha ʻia me "250/125" ma kahi ʻaoʻao a me "AMS" ma kēlā ʻaoʻao (no ke ʻano he 250 mg + 125 mg).

Nā papaʻiʻī, nāʻaina ʻoniʻoni, keʻokeʻo a ʻemi paha ke keʻokeʻo, ʻōwili me ka mālamalama biconvex (ma ke ʻano he 500 mg + 125 mg).

ʻO nā waiwai Pharmacological

Lapaʻau lāʻau

ʻO Amoxicillin a me clavulanic acid i hoʻopau ʻia ma kahi hopena wai i pH o ke kino. Hoʻopili maikaʻi ʻia nā māhele ʻelua ma hope o ka lawelawe waha. E kūpono e lawe i ka amoxicillin / clavulanic acid i ka wā a i ka hoʻomaka ʻana o kahi pāʻina. Ma hope o ka lawelawe waha, ka bioavailability o amoxicillin a me clavulanic acid ma kahi o 70%. ʻO ka poʻokela o ka launa o ka lāʻau i loko o ke kaila o nā mea like ʻelua like. Loaʻa ka ʻike Serum serum i ka hola 1 ma hope o ka hoʻokele ʻana.

Hoʻohālikelike ʻia nā ʻano ʻo amoxicillin a me ka waila clavulanic i loko o ka serum koko i ka wā e lawe ai i ka hui pū ʻana o nā mākau hoʻāla a amoxicillin / clavulanic e like nō me ka mea i ʻike ʻia me kahi lawelawe hoʻokaʻawaʻawa o ka waha o ka hui kūlike ʻo amoxicillin a me ka clavulanic acid.

Ma kahi o 25% o ka nui o ka huina clavulanic a me 18% o ka amoxicillin e hoʻopaʻa ai i nā protein plasma. ʻO ka nui o ka hoʻolaha no ka hoʻokolohua waha o ka lāʻau lapaʻau e pili ana i ka 0.3-0.4 l / kg o ka amoxicillin a me 0.2 l / kg o ka waikawa clavulanic.

Ma hope o ka hoʻokō ʻana i ka intravenous, ua loaʻa nā amoxicillin a me ka waʻa clavulanic i loko o ka pā ʻana o ka gall, kahe o ka ʻōpū o ka ʻōpū, ka ʻili, ka momona, ka ʻaoʻao o ka ʻōpū, ka synovial a me ka peritoneal wai, ka ʻōpū a me ka ihu. Amoxicillin i komo hewa i loko o ka wai o ka cerebrospinal.

ʻO Amoxicillin a me clavulanic acid e hoʻōla i ka paepae placental. Ua hoʻoili ʻia nā mea ʻelua i ka waiū umauma.

ʻO Amoxicillin i hoʻokaʻawale ʻia i loko o ka urine ma ke ʻano o ka waikawa penicillic inactive ma loko o nā huina o 10 - 25% o ka pākuʻi mua. Hoʻomomi ka huika Clavulanic i loko o ke kino a hoʻopiʻi ʻia i loko o ka pāʻai a me nā mea ʻai, a me ke ʻano o ka carbon dioxide me ka ea hanu.

ʻO ka hapalua hapalua hapalua o nā amoxicillin / clavulanic acid ka mea ma kahi o 1 hola, a ʻo ka nui awelika o ka welu he 25 l / h. Ma kahi o 60-70% o ka amoxicillin a me 40-65% o ka clavulanic acid e hoʻopiʻi ʻole i ka loli i ka urine i ka 6 mau hola mua ma hope o ka lawe ʻana i hoʻokahi lemona o nā papa waika amoxicillin / clavulanic. I loko o nā noiʻi like ʻole, ua loaʻa ka 50-85% o amoxicillin a me 27-60% o ka clavulanic acid e hoʻopio ʻia i loko o ka urine i loko o 24 mau hola. ʻO ka nui loa o ka waikawa clavulanic i hoʻopili ʻia i ka wā 2 mau hola ma hope o ka noi.

ʻO ka hoʻohana like ʻana o ka probenecid e hoʻolei ana i ka hoʻokuʻu o ka amoxicillin, akā ʻaʻole i pili kēia lāʻau i ka excretion o ka clavulanic acid ma o nā keiki.

ʻO ka hapalua o ka ola o ka amoxicillin e like me nā keiki i hala 3 mau makahiki a i 2 mau makahiki, i nā keiki a me nā pākeke. I ka hoʻonoho ʻana i ka lāʻau lapaʻau i nā keiki liʻiliʻi loa (me nā pēpē preterm) i nā hebedoma mua o ke ola, pono ʻole e lawelawe ʻia ka lāʻau lapaʻau ma mua o ʻelua mau manawa i ka lā, e pili pū ana me ka nui o ke ala o ka renal excretion ma nā keiki. Ma muli o ka ʻike pono ʻia o nā maʻi maʻi ʻōpala, pono ke kuhikuhi ʻia ka lāʻau lapaʻau me ka mālama pono ʻole i kēia pūʻulu o nā maʻi, akā inā pono, pono ke mālama ʻia ka hana o ka hana.

ʻO ka huina piha o ka amoxicillin / clavulanic acid i ka plasma e hoʻemi ana i ka kūlike pololei i ka hoʻemi ʻana o ka hana ʻoi. ʻOi ka hoʻohaʻahaʻa i ka hoʻopale amoxicillin e hōʻike hou ʻia i ka hoʻohālikelike clavulanic, no ka mea nui ka nui o ka amoxicillin e hoʻopili ʻia ma o nā keiki. No laila, i ke kuhikuhi ʻana i ka lāʻau lapaʻau i nā mea maʻi me ka pilikia ʻole, pono ke hoʻoponopono ʻia e pale ai i ka hōʻiliʻili nui ʻana o nā amoxicillin a mālama i ka pae pono o ka waila clavulanic.

Ke koho ʻana i ka lāʻau lapaʻau i nā mea maʻi me ka nele o ka puʻuwai, pono e hoʻomaʻamaʻa i ka wā e koho ana i kahi pākala a mālama pono i nā hana o ka ate.

Lapaʻau lāʻau

ʻO Amoxicillin kahi antibiotic semi-synthetic mai ka hui penicillin (beta-lactam antibiotic) e kāohi ana i hoʻokahi mau mea hou aʻe (a i kapa pinepine ʻia ʻo penicillin-nakinaki pū) ka mea i komo i ka biosynthesis o peptidoglycan, he mea nui ka hana hiʻona o ka paia o ka pa selia. Ke hōʻike nei i ka syntept peptidoglycan e alakaʻi i ka nāwaliwali o ka paia o ke kelepona, maʻamau ʻia e ka cell lysis a me ka make cell.

Ua luku ʻia ʻo Amoxicillin e ka beta-lactamases i kū ʻia e nā pōʻino kū kūpaʻa, a, no laila, ʻaʻole i komo ka sproxionil o nā hanaxicillin wale nō me ka hana ʻana i kēia mau enzymes.

ʻO Clavulanic waikawa he beta-lactam i hoʻopili pili me nā penicillins. Hoʻopili ia i kekahi mau beta-lactamases, ma laila e pale ai i ka hoʻopono ʻole o ka amoxicillin a hoʻonui i ka lawelawe o nā hana. Clavulanic acid ʻaʻole loa he hopena o ka maʻi antibacterial koʻikoʻi.

ʻO ka manawa ma luna o ka manawa liʻiliʻi o ka pipili liʻiliʻi liʻiliʻi (T> IPC) i manaʻo ʻia ʻo ka mea nui o ka hopena o ka hopena o ka hopenaxicillin.

ʻO nā papa hana kino ʻelua i kū kūʻē aku ai i ka amoxicillin a me nā waila clavulanic:

kaohi ʻana ma o bacterial beta-lactamases ʻaʻole i paʻa i ka acid clavulanic, me nā papa B, C a me D.

kahi loli i nā protein paʻa penicillin-binding, e hōʻemi ana i ka pilina o ka huakaʻi antibacterial i ka pathogen kiko.

ʻO ka hemahema o nā bakiʻi a i ʻole nā ​​hana paha o ka pump efflux (ʻōnaehana ʻoihana) ke kumu a hoʻomau i ka pale ʻana i nā kūmole, ʻoi aku ka nui o ka bacteria-Negative.

ʻO nā palena palena o ka MIC no ka amoxicillin / clavulanic acid ka mea i hoʻoholo ʻia e ke Komite ʻEulopa no ka hōʻike ʻana i ka Antimicrobial Sensitivity (EUCAST).

Nā hōʻailona no ka hoʻohana ʻana

Hoʻomaopopo ʻia ʻo Amoklav no ka mālama ʻana i nā maʻi i hala aʻe i ka pākeke a me nā keiki.

• sinusitis bakteria hopena (ua hōʻike pono ʻia)

• Kīwaha o ka kiko kikoʻī

• Ka hopena o ka niho niho me ka pālahalaha ʻana o ka aʻalolo i ka kiko subutanutan. ʻO nā pono kūpono no ka hoʻohana pono ʻana o nā lāʻau antibacterial e pono e noʻonoʻo pono.

ʻLoe a me ke kākele

Ua kau ʻia nā maʻi ma muli o nā kumuwaiwai o amoxicillin / clavulanic acid i ka mākaukau, ke ʻole nā ​​kau i kau ʻia nā pala ma muli o nā kiko o nā mea.

Ke koho ʻana i kahi maʻa o Amoclav no ka mālama ʻana i nā maʻi ʻōpiopio, pono e noʻonoʻo ʻia kēia mea:

• Pāʻeha i kā lākou hopohopo a me ko lākou ʻike i ka lāʻau antibacterial (e nānā i nā "Hōʻalo"

• ka hōʻeha a me ka hoʻonohonoho ʻana i ka maʻi

• ʻ ,ʻelemakule, ke kaumaha, a me ka hana ʻana o ka maʻi i ka mea maʻi

Inā pono, hiki ke hoʻohana ʻia nā ala ʻē aʻe o Amoklav (e komo pū ana me nā dosis nui o ka amoxicillin a / a i ʻole nā ​​ʻano like ʻole o ka amoxicillin a me nā clavulanic acid) (e nānā i nā "Nā Mīwīwē").

No nā pākeke a me nā keiki ke kaupaona ʻia he 40 kg a ʻoi aku paha, ʻo ka huina o kēlā me kēia lā ʻo Amoklav-375 he 750 mg o amoxicillin / 375 mg o ka clavulanic acid i ka wā e hoʻohana ʻia e like me nā ʻōlelo i hōʻike ʻia ma lalo nei. Inā pono e hoʻohana i kahi lāʻau kiʻekiʻe o ka lāxicillin kiʻekiʻe i kēlā me kēia lā, ʻoi aku ka hoʻohana ʻana o nā ala ʻē aʻe o Amoklav i mea e pale aku ai i nā kulekele kiʻekiʻe o kēlā me kēia lā o ka clavulanic acid (e nānā i nā "Hoʻomaʻawale").

ʻO nā pākeke a me nā keiki ke kaupaona ʻana i ka 40 kg a ʻoi aku ma mua o 1 papa 250 mg / 125 mg ʻekolu mau manawa i ka lā.

Ke kaupaona nei nā keiki ʻaʻole he 40 kg

No nā keiki me ke kaumaha o ke kino ma lalo o 40 kg, ua kāhea ʻia nā papa ʻelua o Amoklav-375:

ʻAʻole pono nā maʻi maʻi kahiko.

ʻO ka maʻi me ka hana renal impaired

Kuhi ʻia ka hoʻoponopono ʻana i ka dosis ma ka nui o ke ʻano loiloi ʻo amoxicillin.

I nā mea maʻi me kahi mana clearanine clearance (CrCl) o kahi o 30 ml / min aku, ʻaʻole i koi ʻia ka hoʻoponopono ʻana.

Ke kaupaona nei nā keiki ʻaʻole he 40 kg

No nā keiki me ka hapa o ke kino e emi iho ana ma mua o 40 kg a me kahi waiwai hoʻonaninani creatinine i emi iho ma mua o 30 ml / min, ka hoʻomohala ʻana o ʻAmoclav-375 me kahi 2: 1 ratio o ka amoxicillin / clavulanic acid, ʻaʻole i ʻōlelo ʻia, no ka mea, ʻaʻohe hiki ke hoʻoponopono ʻia. No kēlā mau mea maʻi, ua kono ʻia ʻo Amoclav me kahi amoxicillin / clavulanic acid acid o 4: 1.

ʻO nā mea maʻi me ka hana pūlima hemahema

Hoʻololi ʻia ka mālama ʻana me ka akahele; ka kiaʻi pinepine ʻia ka hana o ka ate (e ʻike i nā "Contraindications" a me "precautions").

Ua koho ʻia ʻo Amoklav no ka hoʻohana waha.

Hoʻomaopopo ʻia e lawe ʻoe i ka lāʻau lapaʻau ma ka hoʻomaka ʻana o ka ʻai e hōʻemi i nā pilikia gastrointestinal a hoʻomaikaʻi hou i ka komo ʻana o ka amoxicillin / clavulanic acid.

Ke keu

ʻOi paha ka hoʻomohala ʻana o nā ʻōpū mai ka gastrointestinal tract, a me ka uaki ʻole ʻia o ka pae ʻana o ka wai-electrolyte. ʻO nā hihia o ka crystalluria e pili ana i ka amoxicillin, ua nānā ʻia i kekahi manawa i ka hemahema o ka renal.

ʻO nā mea maʻi me ka hana renal impaired a loaʻa ʻole ke kiʻekiʻe kiʻekiʻe o ka lāʻau e hoʻomohala i ka make. No nā hōʻailona gastrointestinal, hiki ke hāʻawi ʻia ke ʻano hōʻailona me ka hoʻihoʻi ʻana i ka kaila wai-electrolyte. ʻO Amoxicillin a me clavulanate potassium hiki ke hoʻopili ʻia e ka hemodialysis.

Hoʻopili pū me nā lāʻau ʻē aʻe

Ua hōʻike ʻia nā ala o ka hoʻonui ʻana i ka pae o ka honua maʻamau (INR) i nā maʻi maʻi e mālama nei i ka mālama mālama ʻia me ka acenocoumarol a i ʻole warfarin e kū'ē i ke kumu o ke ʻano o ka papaxicillin i ʻōlelo ʻia. Inā pono, ʻo ka mālama like ʻana o nā lāʻau lapaʻau e kiaʻi pono i ka manawa prothrombin a i ʻole INR i ka hoʻomaka ʻana o ka mālama ʻana a ma hope o ka hoʻopau ʻana o ka mālama ʻana me ka amoxicillin. Hiki ke koi ʻia kahi hoʻoponopono ʻana o ka anticoagulants waha.

Hiki i nā penicillins ke hōʻemi i ka ʻokiʻoki o ka methotrexate, ka mea i hoʻopili ʻia e ka nui o nā toxicity.

ʻAʻole aʻo ʻia ka hoʻohana pinepine ʻana o probenecide. Hoʻemi ia i ka mea huna o ka amoxicillin i loko o nā tubal renal. ʻO ka hoʻohana like ʻana o ka probenecid me Amoclav hiki i ka hoʻonui i ke kahe o ke kō o ka amoxicillin (akā ʻaʻole ko clavulanic acid) a me ko lākou mālama hou aku.

ʻO nā mea mālama palekana

Ma mua o ka hoʻomaka ʻana i ka mālama ʻana me Amoclave, pono ia e hōʻiliʻili i ka moʻolelo olakino pili e pili ana i nā hopena hypersensitivity o mua i nā penicillins, cephalosporins a i nā hoʻomākaukau ʻē aʻe beta-lactam.

Ka ʻike koʻikoʻi a me ka manawa lethal hypersensitivity kūlia (anaphylactoid reaksi) i nānā ʻia ma ka lāʻau penicillin. Kēia aʻe paha ka hoʻomohala ʻana i nā maʻi me nā maʻi hypersensitivity i nā penicillins a me kahi mōʻaukala o ka atopy. Inā ulu kahi hopena alerine, ua hoʻoneʻe ʻia ke ʻano ʻo Amoclav a ua kuhikuhi ʻia nā lāʻau lapaʻau kūpono ʻē aʻe.

I nā hihia i hōʻike ʻia o ka hiki ʻana i nā pathogens maʻi i ka amoxicillin, pono e noʻonoʻo e noʻonoʻo i ka hoʻololi ʻana mai Amoclav i ka amoxicillin e like me nā kulekele kūlike.

ʻAʻole kūpono kēia ʻano kūpono o ka lāʻau lapaʻau no ka hoʻohana inā he ke kiʻekiʻe kiʻekiʻe e kūpaʻa ka pathogens i ʻaihue ʻia no ka hoʻomākaukau ʻana no ka beta-lactam ʻaʻole i hoʻopaʻa ʻia e ka beta-lactamases ma ka pale ʻana i ka hopena pale o ka acid clavulanic. No ka mea ʻaʻohe ʻikepili pilikino ma T> IPC (ka emi ʻana o ka pale o ka liʻiliʻi), a me nā hopena o ka loiloi ʻana i nā ʻano hoʻohālikelike waha i hoʻohālikelike ʻia ka palena, hiki i kēia ʻano hana (me ke ʻano o ka amoxicillin) ʻaʻole kūpono no ka mālama ʻana i nā maʻi i hoʻohewa ʻia e nā penisillin-tahan S.pheumoniae.

I nā maʻi me nā hana renal impaired a i ʻole e hoʻomohala ai i ka holo. Hōʻike ʻo Amoclav i kahi maʻi i loko o ka maʻi mononucleosis hopohopo, mai ka hope o ka hoʻohana ʻia ʻana o ka maʻi maʻi, ua ʻike ʻia ke ʻano o ka nui o ka pīpī.

ʻO ka hoʻohana pono ʻana o ka allopurinol i ka wā mālama me ka amoxicillin e hoʻonui nui aʻe i ka hopena o ka ulu ʻana i nā ʻano maʻi alaka.

ʻO ka hoʻohana lōʻihi ʻana o ka lāʻau lapaʻau hiki ke alakaʻi i ka hoʻopiʻi nui o nā microorganisms refractory.

ʻO ka hoʻomohala ʻana i ka erythema maʻamau me ka hoʻomohala a me ka hoʻomohala ʻana i nā pustules i ka hoʻomaka ʻana o ka maʻi maʻi, he hōʻailona mau o ka pousulosis exanthematous maʻamau (OGEP) (e ʻike i nā "ʻaoʻao ʻaoʻao"). Pono kēia ʻano hana i ka hoʻōki ʻana o ka maʻi me Amoclave a he contraindication i ka hoʻokō o ka amoxicillin e hiki mai ana.

Hoʻohana ʻia ka mālama ʻana o nā mea maʻi me ka maikaʻi ʻole o ka ate.

ʻO nā hanana ʻino loa mai ka ate ka mea i ʻike nui ʻia i nā kāne a me nā poʻe maʻi maʻi a pili paha i ka mālama ʻana i ka wā lōʻihi. ʻO nā hanana kūpono i nā hihia līpoki ʻaʻole i ʻike ʻia i nā keiki.

I nā hui āpau o nā mea maʻi, nā maʻi a me nā hōʻailona e ulu a i ka wā ma hope o ka mālama ʻana, akā i kekahi mau mea ke ʻike ʻia he mau hebedoma wale nō ma hope o ka hoʻokuʻu ʻana i ka lāʻau. ʻO ka maʻamau pinepine lākou i ka hoʻololi. Hiki i nā hanana ʻinoʻino mai ka lūlū e hiki ke ulu, ʻokoʻa loa me kahi hopena hōʻeha. Hoʻopaʻa pinepine ʻia lākou ma waena o nā poʻe maʻi me nā maʻi kūlohelohe koʻikoʻi a lawe pū paha i nā lāʻau lapaʻau e hiki ai ke hoʻopilikia i ka ʻāʻū (e ʻike i nā "Side effects").

ʻO nā hihia o nā colitis e pili ana i ka antibiotika i mālama ʻia i ka wā o ka terapi me nā lāʻau āpau antibacterial, me ka amoxicillin, hiki ke loli i ka hōʻeha mai ka hoʻoluʻu ʻana i ke ola (ʻike "Side effects").

He mea nui ia e hōʻike i kēia maʻi i nā maʻi me ka maʻi mau i ka wā a ma hope o ka pau ʻana o kekahi o ka papa lāʻau antibiotic. Ma ka hihia o ka hoʻomohala ʻana i ka colitis e pili ana i ka antibiotika, ua hoʻopau koke ʻia ke ʻano ʻo Amoclave, e nīnau me ke kauka a hana i ka mālama kūpono. I kēia kūlana, ua contraindicated ke hoʻohana ʻana i nā lāʻau lapaʻau e hoʻoneʻe ana i ka peristalsis.

I ka wā lōʻihi, ʻo ka loiloi loiloi manawa o nā hana o nā ʻōnaehana like ʻole, me nā huaʻōlelo, ʻāʻī a me nā ona o ke koko.

Ma nā hihia lohi, ʻoiai ke lawe nei i ka lāʻau, ua hoʻomaopopo ʻia kahi hoʻonui o ka manawa prothrombin. Me ka hoʻokolohua pinepine ʻana o nā anticoagulants, ka mālama pono ʻana i nā hōʻailona coagulation he kauoha. Hiki i kahi hoʻoponopono lōkahi o nā anticoagulants waha e hoʻokō i ka pae i makemake ʻia o ka anticoagulation.

I ka poʻe maʻi me ka maʻi kīkē, e koi ʻia kahi hoʻoponopono ʻana e like me ke kiʻekiʻe o ka maʻi (ʻike "Dosage and Administration").

I ka poʻe maʻi me ka diuresis ho'ēmi, crystalluria i nānā pinepine ʻia, ka mea nui i ke kūkaʻi ʻana o ka lāʻau lapaʻau.I ka wā o ka lapaʻau amoxicillin kiʻekiʻe, ua hoʻolako ʻia ka inu nui i ka wai e hōʻemi i ka hopena o ka crystalluria e pili ana i ka amoxicillin. I ka poʻe maʻi me ka catheter i hoʻokomo ʻia i loko o ka wahi pā, pono ia e kiaʻi pinepine i kāna patty. I ka wā e mālama ai i ka glucosuria, e nānā ʻia nā pae glucose e hoʻohana ana i nā hana enzymatic me ka glucose oxidase, no ka mea, ʻaʻole i hāʻawi ʻia nā hopena non-enzymatic i nā hopena maikaʻi ʻole. ʻO ka heleʻana o ka mika clavulanic ma Amoklava e hiki ke hoʻopaʻa i ka lehele ʻole o IgG a me ka albumin i nā membrane erythrocyte, kahi e hiki ai i nā hopena maikaʻi ʻole o ka hoʻokolohua Coombs.

Aia ua loaʻa nā maʻi o ka immunosorbent assay-e pili ana i ka maʻi (ELISA) no Aspergillus i nā poʻe maʻi e loaʻa nei i ka lāʻau lapaʻau, ka mea i hoʻoholo hou aʻe i ka haʻalele ʻana o nā maʻi i hoʻokumu ʻia e Aspergillus. ʻO nā hui kū ʻana me ka non-aspergillosis i hoʻomaopopo ʻia

polysaccharides a me polyfuranoses ma ke ʻano o ka hōʻike ʻo ELISA ma Aspergillus. ʻO nā hopena hōʻike maikaʻi i nā maʻi e lawe ana iā Amoklav e pono e unuhi me ka akahele a hōʻoia ʻia i nā hana diagnostic ʻē aʻe.

Dosages no nā keiki

No nā mea maʻi liʻiliʻi, e helu mau ʻia ka pākuʻi o kēlā me kēia lā ʻo Amoxiclav e pili ana i ka papa i nā kauoha:

• a i 3 mau mahina, e kuhikuhi ʻia ana ʻo Amoxiclav i kahi nui o 30 mg / 1 kg o ke kaumaha o ka kino i ka lā, i hoʻokaʻawale ʻia i 3 mau pākahi i kēlā me kēia lā,
• mai 3 mau mahina a hiki i 12 mau makahiki, e kau ʻia ka nui o kēlā me kēia lā e like me ka ʻano 20 mg / 1 kg o ka paona no ka maʻi maʻi, a i ʻole 40 mg / 1 kg no nā maʻi ʻino, ua hoʻokaʻawale ka nui o ka hopena o ka lāʻau i loko o 3 mau wahi a hāʻawi ʻia i nā manawa maʻamau.
• Mai ka 12 o nā makahiki, hiki i nā keiki ke lawe i nā inikua pākeke.

ʻO ka lōʻihi o ka mālama ʻana i nā keiki ma mua o nā lā he 5-7 mau lā. ʻO kēia ka hapalua e like me ka poʻeʻelemakule. Inā pono, e hoʻonui ke kauka i ka papa o ka lāʻau lapaʻau.

Nā manaʻo Amoxiclav

ʻO ka hapa nui o nā loiloi e pili ana iā Amoxiclav. Kokoke koke ma hope o ka lawe ʻana i ka lāʻau lapaʻau, nā nāwaliwali o nā hōʻailona, ​​ʻano palupalu a ʻaʻole hoʻi paha. Ma nā hihia kaawale, nā mea maʻi a me nā poʻe e maʻi ana i nā maʻi ʻōpū e hoʻopiʻi i ka hoʻopiʻi e pili ana i ka edema, e hōʻike ana i ka hana pono ʻana o nā mea nui. ʻAʻole noʻonoʻo ʻia kēia kūlana, ʻoiai inā noʻonoʻo ʻoe e hoʻopili ʻia e nā clavulanic acid e lākou. I ka manawa like, hoʻonui ka lāʻau i kona hopena, hiki ke loaʻa nā hōʻailona o kahi overdose. I mea e pale ʻole ai i kēia mea, pono e lawe ʻia nā hana pale - inu nui i nā wai a ʻike pinepine i ke kauka.