ʻO Orlistat-Akrikhin: nā ʻōlelo e hoʻohana ai a e loiloi

Latin inoa: Orlistat-Akrikhin

Manaʻo Pūnaewele ATX: A08AB01

Mea hana kūpono: orlistat (orlistat)

Mea Hana: Polfarma S.A.

Hoʻouka i ka wehewehe a me ke kiʻi: 11.28.2018

ʻO nā kumukūʻai i nā lāʻau lapaʻau: mai 674 mau rubles.

ʻO Orlistat-Akrikhin - kahi lipid-kaila haʻahaʻa, kahi lipase inhibitor o ka gastrointestinal tract.

E hoʻokuʻu i ke ʻano a me ka ʻano

Hoʻopuka lākou i ka huahana i ke ʻano o nā kapapena: ka nui No. 1, ka gelatin paʻakikī, ka uliuli, nā kiko o nā capsules he keʻokeʻo keʻokeʻo a i ʻole agglomerates i hoʻohui ʻia (7 a i ʻole 14 mau pcs. I kahi blister, i loko o ka pahu kāleka 3 blisters o 7 pcs., A me 3 blisters o 14 pcs. ., a i ʻole 6 molomo o 14 pcs. a me nā ʻōlelo no ka hoʻohana ʻana iā Orlistat-Akrikhin).

1 kiaʻi pahu:

• mea waiwai: orlistat - 120 mg,
• Nā kumuhana hou: sodium carboxymethyl starch, microcrystalline cellulose, sodium lauryl sulfate, anhydrous colloidal silicon dioxide,
• capsule shell: titanium dioxide (E171), gelatin, indigo carmine (E132).

Lapaʻau lāʻau

ʻO Orlistat kahi lōkela o ka lipase gastrointestinal lōʻihi. Hoʻonui kēia mea i kona hopena ma ka lumen o ka ʻōpū a me ka pūpū liʻiliʻi ma o ka hoʻokumu ʻana i kahi paʻa covalent me ke kikowaena serine ikaika o nā lipases a me ka pancreatic lipases. Ma muli o ka hopena o ka ʻaina lipid-hoʻohaʻahaʻa, ua hoʻoneʻe ka enzyme inactivated i ka hiki ke wāwahi i nā momona i hāʻawi ʻia i ka meaʻai ma ke ʻano o ka triglycerides (TG) i ka monoglycerides a hoʻoulu i nā a momona momona. No ka mea, ʻaʻole i hoʻokaʻawale ʻia nā TGs mai ka gastrointestinal tract (GIT), heʻuʻuku ka nui o nā kalora i ke kino, a ma muli o ke emi ʻana o ka paona o ke kino. Pēlā, e lawe ʻia ana ka hopena therapeutic o ka lāʻau me ka ʻole o kona komo ʻana i ka ʻōnaehana ʻōnaehana. Ma muli o ka hana o ka orlistat, 24-48 mau hola ma hope o ka lawelawe waha o ka lāʻau i loko o ka hana, nui ka piʻi ʻana o ka momona. Ma ke alakaʻiʻana i ka emi ʻana o ka momona depot, hāʻawi ʻo Orlistat-Akrikhin i ka mana kūpono o ka paona kino.

Ma nā hoʻokolohua lapaʻau, ʻoiai me nā mea maʻi obese, i ka hui o nā mea maʻi e loaʻa ana i ka orlistat, he nui ka hewa o ka nui o ke koʻikoʻi o ke kino e hoʻohālikelike ʻia me nā mea maʻi i ka meaʻai wale nō. Ua mālama ʻia ka lilo ʻana o ka paona ma nā hebedoma mua ma hope o ka hoʻomaka ʻana o ka hoʻokele ʻana o Orlistat-Akrikhin a ma hope iho no 6-12 mau mahina inā he hopena maikaʻi ʻole ka hopena o ka mālamaʻai.

Ka hoʻokō nui ʻana i ka hoʻomaʻamaʻa nui ʻana i loko o ka pūliki o ka hanana me ka hopena o ka momona obesity i hoʻopaʻa ʻia ma mua o ʻelua mau makahiki. Eia kekahi, loaʻa i kahi emi nui o nā waihona momona momona i ka wā e hoʻohālikelike ʻia me ka hui pletebo. Ua hōʻike pū ʻia ʻo Orlistat i mea maikaʻi i ka wā i hoʻohana ʻia no ka pale ʻana i ka uku paona. Ma kahi o ka hapalua o nā mea maʻi e hōʻike ana i ka piʻi o ka nui o nā mea ʻaʻole iʻoi aku ma mua o 25% o nā mea i nalowale, a ma ka hapa ʻelua o nā mea e komo ana i ka hoʻopaʻa ʻana, ʻaʻohe kauā kau paona ʻana, a i ʻole he kaupaona ʻana ma hope o ke kaupaona ʻana.

I ka wā o nā hoʻokolohua lapaʻau, ʻo ia ka mau mea mai 6 mau mahina a i ka makahiki 1, nā mea maʻi me ka momona momona a me ka momona a me ka type 2 diabetes mellitus i ka wā e hoʻohana ai i ka orlistat i hōʻike i ka nui o ke kaumaha o ke kino e hoʻohālikelike ʻia me nā mea maʻi e pili ana i ka lāʻauʻai. Ma muli o ka emi ʻana o ka paona ʻana ma muli o kahi o ka emi ʻana o ka hoʻohaʻahaʻa ʻana o nā mau momona momona i loko o ke kino. Pono e hōʻike ʻia, i nā mea maʻi e komo i ka noiʻi ʻana, ʻike ʻole ʻia ka mālama glycemic pinepine ʻia e pili i ka lawe ʻana i ka lāʻau antidiabetic. Ke mālama nei i ka orlistat i kēia mau maʻi, ua loaʻa kahi holomua nui i ka mana glycemic. Eia nō hoʻi, i ka wā i hoʻohana ai ʻo Orlistat-Akrikhin, kahi i emi iho ai o nā koina o nā ʻāpana o antidiabetic, ka mālamaʻana i ka insulin, a me kahi emi o ka pale ʻana i ka insulin.

Wahi a nā haʻawina e mau ana he 4 mau makahiki, ua ʻike ʻia me ka maʻi orlistat, ua hoʻemi nui ʻia ka nui o ka maʻi mellitus type 2 - he awelika o 37% hoʻohālikelike ʻia me ka placebo. Ua hōʻemi ʻia kēia hoʻoweliweli e pili ana i ka 45% i nā mea maʻi me ka hoʻomanawanui i ka hoʻohaʻahaʻa glucose kumu. I ka hui e loaʻa ana i ka orlistat, he nui ka emi ʻana o ke koʻikoʻi o ke kino ma ke ʻano o ka hui pletebo, a me ka hoʻohui - i kahi hoʻomaikaʻi koʻikoʻi o ka hana o nā mea kūlohelohe metabolic. Loaʻa ka pae hou hou o ke kino o ke kino i ka manawa o 4 mau makahiki o ke aʻo ʻana.

I ka poʻe'ōpiopio me ka momona, kahi haʻahaʻa 1 makahiki i ka maikaʻi o ka mālama ʻana me ka orlistat i hoʻopaʻa i ka hoʻemi ʻana o ka index mass body (BMI), a me ka hoʻohaʻahaʻa ʻana i ka momona o ke kino a me ka noho ʻana o ka pūhaka a me nā kuʻekuʻe hoʻohālikelike i ka hui plasebo. Eia nō hoʻi, i ka wā i hoʻokele ai ʻo Orlistat-Akrikhin, ua hōʻike nā ʻōpio i ka nui o ka hōʻemi ʻana i ka pehu koko diastolic (BP) i hoʻohālikelike ʻia me nā poʻe i loaʻa i kahi pletebo.

Lapaʻau lāʻau

Hōʻike ʻia ka lāʻau lapaʻau e ka haʻahaʻa haʻahaʻa. 8 mau hola ma hope o ka lawelawe waha ʻana i ka plasma, ʻaʻole i hoʻoholo ʻia ka papa inoa ʻole, ʻaʻole ʻoi aku ka nui o nā mahele o ka 5 ng / ml. ʻAʻole i ʻike ʻia nā hōʻailona o ka hoʻopili ʻana o ka mea hana, e hōʻike ana i kahi pae liʻiliʻi loa o ka paʻa ʻana.

ʻAʻole hiki ke hoʻokumu i ka lehulehu o ka hoʻoili, ʻoiai ʻaʻole e hoʻopili ʻia ka huahana. I loko o vitro, nakinaki ia i nā protein plasma i aneane holo (99%), ʻoi loa me nā lipoproteins a me nā albumin. Ma ka liʻiliʻi liʻiliʻi, hiki i ka huahana ke komo i loko o nā ʻāpana koko ʻulaʻula. ʻO ka hoʻololi ʻana o ka metabolic o ka orlistat ka hapanui i ka paia o ka ʻōpū ma ka hoʻokumu ʻana o nā metabolites ʻelua i ʻole e hōʻike i ka hana pharmacological - M1 (ʻehā lactone hydrolyzed lactone pākuʻehā) a me M3 (M1 me kahi koina N-formylleucine i holoi ʻia).

Ua hoʻoneʻe loa ʻia ka waiwai ma loko o ka ʻōpū - e pili ana i ka 97% o ka nui i lawe ʻia, ma kēia ʻano ua loli - e pili ana i ka 83%. ʻO ka nui o ka hoʻopiʻi ʻana o nā metabolites āpau o orlistat e nā keiki, ʻaʻole iʻoi aku ma mua o 2% o ka loaʻa i ka hopena o ka lāʻau. ʻO ka manawa o ka hoʻopau pihaʻana o ka waiwai me nā feces a me ka urine he 3-5 lā. ʻO nā ala no ka hoʻopauʻana i ka orlistat i nā mea maʻi me ke kaumaha kino kino a me nā hiʻona e like. Eia kekahi, nā mea ikaika a me nā metabolites hiki ke hoʻopili ʻia me ka hua bile.

Nā hōʻailona no ka hoʻohana ʻana

A ʻōlelo ʻia ʻo Orlistat-Akrikhin no ka lāʻau lōʻihi o ka poʻe maʻi me ka momona me ka BMI ≥ 30 kg / m² a i nā mea maʻi me ke kaumaha paha me kahi BMI ≥ 28 kg / m², he mau pōpilikia pākaʻi e pili ana i ka obesity, e kūloko ai ma kahi kaʻai o ka mea haʻahaʻa haʻahaʻa haʻahaʻa.

Hāʻawi ʻia ʻo Orlistat-Akrikhin no ka hoʻohana ʻana i nā mea maʻi me ka maʻi diabetes mellitus type 2 me ka momona o ka momona a i ʻole ka momona i hui pū ʻia me ka pāʻai hypocaloric haʻahaʻa a me / a me nā lāʻau hypoglycemic (e hana ʻia ana a / a i ʻole derony sulfonylurea, metformin).

Nā Hoʻohui

• cholestasis
• ʻālaʻi melabsorption,
• makahiki a hiki i ka 12 makahiki
• hapai a me lactation,
• hypersensitivity o kekahi o nā ʻāpana o Orlistat-Akrikhin.

Me ka mālama nui, pono ka lāʻau e mālama me ka hoʻohana ʻana i ka cyclosporine, warfarin, a i ʻole nā ​​anticoagulants waha.

Nā hopena hopena

Hōʻike ʻia nā hopena e hōʻino ʻia e ka hoʻokele orlistat i nā hapanui mai ka ʻeha o ka gastrointestinal a ua pili pū me ka hana ʻoihana pharmacological o kahi mākaʻikaʻi e kāohi ana i ka hoʻopoʻi ʻana o nā kīʻaha meaʻai.

I ka wā o ka hoʻokele ʻana o Orlistat-Akrikhin, hiki ke hōʻeha ʻia nā ʻaelike penei:

• ka hoʻonāola a me nā maʻi ʻai: pinepine pinepine - hypoglycemia,
• hopohopo a me nā maʻi palupalu: pinepine pinepine - i ka maʻi,
• ʻūnaehana sistema: pinepine pinepine - kuʻuna,
• mau manaʻo noʻonoʻo: pinepine ka hopohopo,
• ʻōpū o ka hanu, umauma a me nā ʻōpū mediastinal: pinepine - i luna o ke aho o ka ʻōpū o ke kino, pinepine - ʻeha o nā ʻōpū hanu o ke aho,
• nā ʻōhaka a me nā kelena mammary: pinepine - haehae i ʻole
• nā pēpē a me ka maʻi pālani: pinepine - ka maʻi urinary tract,
• Pahu i ka laka: ka hopena pinepine loa - ke kaila o ka lehelehe mai ka lehelehe, hōʻeha / hōʻeha o ka ʻōpū, ka neʻe ʻana o ka hau me kahi nui o ka hoʻoiho ʻana, ka lemulewa, nā kīʻaha kuʻuna, nui ka makemake e hoʻōla, hoʻonui i nā neʻe o ka ʻihi, steatorrhea, pinepine - ʻeha a ʻehaʻeha / ʻeha i ka ʻala, kuʻuna nā fecal , nā ʻōpala palupalu, pōʻino, hōʻeha kino, hōʻā ʻia o ke kīpū,
• nā maʻi maʻamau: pinepine - nāwaliwali.

ʻO ke ʻano a me ke ʻano o ka hopena o ka hopena i nā mea maʻi me ka maʻi diabetes type 2 e like nō me ka poʻe i nā mea maʻi me ka maʻi maʻi ʻole, ua nui ka momona a me ka momona.

I ka wā o ka mālama ʻana, ʻoi aku ka nui o nā hopena ʻino mai ka gastrointestinal tract me ka hoʻonui ʻana o ka nui o ka momona i ka meaʻai i hoʻopau ʻia. Hiki iā ʻoe ke hōʻalo a hōʻemi paha i ka nui o kēia mau pilikia ma ka hahai ʻana i kahiʻai haʻahaʻa. I ka hapanui o nā maʻi he ʻokoʻa a me ka mālie nā hopena o luna, ua ʻike ʻia ko lākou hiʻohiʻona ma ka 3 mau mahina mua o ka hānai ʻana a me, me he la palena lā, ʻaʻohe o kēlā me kēia hanana. E pale aku i ke ʻano o ka hoʻohana mau ʻana i ka Orlistat-Akrikhin, ua emi ka nui o ka hiki ʻana o kēia mau hanana.

Ke keu

ʻAʻole wehewehe ʻia nā ala o ka lāʻau overdose.

Ke lawe nei i hoʻokahi (800 mg) a me nā helu he nui (ma luna o 15 mau lā a hiki i 400 mg ʻekolu mau manawa i ka lā) orlistat i nā kānaka me ke kaumaha o ke kino kino / momona, ʻaʻole i hele mai nā hopena makemake ʻole. Ke lawe nei i ka orlistat i nā maʻi hānai no nā mahina 6 mau malama i kahi wai o 240 mg ʻekolu mau manawa i ka lā, ʻaʻole i ʻike ʻia ka piʻi ʻana o ka ʻike ʻino.

Ma ka hihia o ka overdose koʻikoʻi o Orlistat-Akrikhin, pono ke kiaʻi ka mea maʻi i loko o 24 mau hola. Wahi a nā haʻawina mua a me ka preclinical, nā hopena o nā loina i pili i ka lipase-inhibiting properties of orlistat e hoʻohuli hou i ka huli.

Nā ʻōlelo kikoʻī

Noi ʻo Orlistat-Akrikhin e hoʻohana ʻia no ka manawa lōʻihi o ka mālama ʻana i ke kaumaha o ke kino (me ka hoʻemi ʻana o ke kaumaha kino kino, mālama pono ʻia ma ke kiʻekiʻe i makemake ʻia a pale ʻia ka loaʻa ʻana o ke kaupaona ʻana).

I ka poʻe maʻi me ka diabetes mellitus type 2, ma muli o ke kaupaona ʻana i ka wā e hoʻohana ai i ka lāʻau, hiki i ka hoʻomaʻamaʻa ʻana i ke kālaiʻana o ka metabolism ka paʻakai, e koi ana i ka emi o ka hopena o ka lāʻau hypoglycemic.

ʻAʻole pono ka lōʻihi o Orlistat-Akrikhin ma mua o 2 mau makahiki. Inā he mau hebedoma ma hope o ka hoʻomaka ʻana o ke papa, ʻaʻole hiki i ka hiki ke hoʻokō i ka pohō o ke koena ma lalo o 5%, pono e hoʻōki ʻia ka hoʻohana ʻana i ka lāʻau.

Inā hōʻike ʻia nā hōʻailona e like me ka palupalu, nāwaliwali, ke kūlohelohe, ka pouli o ka urine a me ka jaundice i ka wā o ka mālama ʻana, pono ia e nīnau i ke kauka e haʻalele i kahi mau hōʻeha o ka puʻuwai.

I ka wā o ka mālama ʻana me ka lāʻau lapaʻau, ʻo ka mea nui i nā mea maʻi me ka hoʻopalapula o ka hoʻopalapula o ka maʻi a me ka dehydration, hiki i ka hyperoxaluria a me ka oxalate nephropathy e ulu, aia i kekahi mau hihia ke alakaʻi i ka nānā ʻana o ka maikaʻi ʻole.

Hoʻohui nūhou

• amiodarone - hiki i ka emi ʻana o ka pae o kēia mau mea i loko o ke koko koko, nānā kiaʻi a nānā ʻia me nā mākaʻi o ECG.
• nā lāʻau antiepileptic - ua hoʻemi ʻia ke komo ʻana o kēia mau lāʻau, hiki ke hōʻeha i ka make,
• cyclosporin - e hoʻemi ʻia ka pae plasma, e hiki ai i ka nāwaliwali o ka hoʻoikaika immunosuppressive o ka lāʻau lapaʻau, ʻaʻole i hui ʻia kēia hui ʻana, inā pono, e nānā pinepine ʻia ka ʻike ʻana i ka plasma ʻaina o ka cyclosporine e koi ʻia me ka hoʻohana pū ʻana o ka hoʻohana a me ka mea pono ma ka papa inoa o ka lālani
• warfarin a me nā anticoagulants - hiki i ka mea ke hoʻemi i ka nānāʻana o ka prothrombin a hoʻonui i ka ratio normalized internationalization IN (INR), hiki iā ia ke alakaʻi i kahi hoʻololi i nā ʻāpana hemostatic, me kēia hui pū ʻana, pono ka nānā ʻana i nā hōʻailona INR.
• nā momona a wai momona A, D, E, K a me beta-carotene - ua nāwaliwali ka ʻike ʻana o kēia mau mea, me ka hoʻohana pū ʻana me lākou no ka hiamoe a i ʻole ʻoi aku ma mua o 2 mau hola ma hope o ka lawe orlistat.
• acarbose - ua manaʻo ʻia e pale aku i ka hoʻohana pono ʻana ma muli o ka nele o nā haʻawina o ka pharmacokinetic interact
• sodiumroxine sodium - hypothyroidism a me / a me ka emi ʻana o kona kāohi i hiki ke hōʻemi ma muli o ka hoʻokahe ʻana o ka pākuʻi levothyroxine a me / a iodine inorganic,
• i ka ulu ʻana i ka maʻi o ka waha - ka puʻu o ka hōʻemi i ka hopena o ka contraceptive e hoʻonui ʻia, i kekahi mau manawa e hoʻonui ai i ka hiki ʻana o kahi hapai i hoʻolālā ʻole ʻia, pono ʻoe e hele i nā ala hou o ka contraception, e komo pū ana inā he maʻi koʻikoʻi.
• antiretroviral agents no ka mālama ʻana i ka maʻi immunodeficiency kanaka (HIV), antipsychotics (me ka hoʻomākaukau ʻana o lithium), antidepressants, benzodiazepines - hiki iā ia ke hoʻonāwaliwali i ka hopena therapeutic o kēia mau lāʻau, a me ka papa inoa o listlistat i kēlā mau mea maʻi e hoʻomaka ʻia ma hope o ka loiloi ʻana i ka pōmaikaʻi o nā mea i manaʻo ʻia o kēia mālama ʻana a me ka hiki. Hoʻopilikia
• fibrates, atorvastatin, digoxin, amitriptyline, biguanides, losartan, pravastatin, fluoxetine, phentermine, sibutramine, nifedipine, phenytoin, ethanol - ʻaʻohe mea i hoʻopili ʻia me kēia mau lāʻau.

ʻO nā analogues o Orlistat-Akrikhin nā: Orsoten, Listata, Orsotin Slim, Orlistat, Xenical, Orliksen 120, Orlistat Canon, Alli, Xenalten Light, Xenalten Logo.

Nā Hōʻikeʻike o Orlistat-Akrikhin

ʻOkoʻa loa nā loiloi e pili ana iā Orlistat-Akrikhin. He nui nā mea maʻi e pane maikaʻi ana i ka lāʻau lapaʻau, me ka ʻōlelo ʻana e hoʻomaikaʻi i kāna hana i hiki ai iā lākou ke nalowale no ka 5 kg o ke kaumaha nui loa i 3 mau mahina. Ma hope o kēlā, ua emi nui ka nui o ke kino, akā ʻaʻole ka wikiwiki. I ka poʻe maʻi me ka hoʻohaʻahaʻa wikiwiki, ʻoi aku ka lōʻihi o ke kaʻina o ke kaumaha. Ma ka manawa like, ʻike nā mea maʻi e hiki iā lākou ke hoʻokō i nā hopena lapaʻau kūpono, pono ia e hoʻoponopono i ka ʻai a me ke ʻano maʻamau - pili i ka meaʻai kūpono e hiki ai iā ʻoe ke hōʻemi i ka nui o nā ʻiʻo i loko o ka papaʻai, hoʻokō i ka hana kino pilikino, hoʻoneʻe i ka nui, a pēlā aku.

ʻO nā pōʻino o Orlistat-Akrikhin i loko o ka hapa nui o ka hopena o nā ulia pōpilikia i loko o ke ʻano o ka lemulewa, nā kīʻaha kūlaki, nā maʻi maʻi, a me ka makemake a peremptory defecate. Akā, ma ke ʻano he kānāwai, ʻike ʻia kēia mau hewa i nā mahina mua o ke ʻano o ka papa lapaʻau a laila hoʻomau iā lākou iho. Maʻalahi pinepine i nā loiloi ma kahi e hōʻike ai i kahi hopena nawaliwali loa o ka lāʻau me ka lāʻau lapaʻau.

ʻO Orlistat-Akrikhin

Nā huahana no ka waiwai

Xenical 120mg 21 pcs. mau kapena F. Hoffmann-la Roche Ltd

F. Hoffmann-La Roche Ltd (Kelemania) hoʻomākaukau ʻana: Xenical

Orsoten 120mg 21 pcs. mau kapala

Krka dd, Novo mesto (Lūkini) hoʻomākaukau: Orsoten

Orsoten Slim 60mg 42 pcs. mau kapala

Krka dd, Novo mesto (Lūkini) hoʻomākaukau: Orsoten Slim

Waiʻau 120mg 30 pcs. pani ʻ -lelo ʻlelo

Kūlana ʻo Izvarino (Lūkini): Listata

Leaf mini 60mg 30 pcs. pani ʻ -lelo ʻlelo

Izvarino (Lūkini) hoʻomākaukau: Listata mini

Nā kikowaena mai nā huahana Huaʻī kaumaha

Xenical 120mg 42 pcs. mau kapena F. Hoffmann-la Roche Ltd

F. Hoffmann-La Roche Ltd (Kelemania) hoʻomākaukau ʻana: Xenical

Reduxin 0,01 + 0.1585 10 mau kāleka. mau kapala

Hoʻomākaukau PromoMed (Lūkini): Reduxin

Orsoten 120mg 42 pcs. mau kapala

Krka dd, Novo mesto (Lūkini) hoʻomākaukau: Orsoten

Orsotin Slim 60mg 84 pcs. mau kapala

Krka dd, Novo mesto (Lūkini) hoʻomākaukau: Orsoten Slim

Hana ʻia 100 pcs. lozenges

Materia Medica Ke hoʻopaʻa ʻana iā NP (Lūkini) Kauka: Dietress

Nā kikowaena mai nā Kauka lāʻau

Xenical 120mg 21 pcs. mau kapena F. Hoffmann-la Roche Ltd

F. Hoffmann-La Roche Ltd (Kelemania) hoʻomākaukau ʻana: Xenical

Reduxin 0,01 + 0.1585 30 mau nākiō. mau kapala

Hoʻomākaukau PromoMed (Lūkini): Reduxin

Orsoten 120mg 21 pcs. mau kapala

Krka dd, Novo mesto (Lūkini) hoʻomākaukau: Orsoten

Orsoten Slim 60mg 42 pcs. mau kapala

Krka dd, Novo mesto (Lūkini) hoʻomākaukau: Orsoten Slim

Waiʻau 120mg 60 pcs. pani ʻ -lelo ʻlelo

Kūlana ʻo Izvarino (Lūkini): Listata

Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana

Nā ʻūpepa - 1 mau kapeke:.

• mea waiwai: orlistat - 120 mg,
• nā mea waiwai: MCC - 59.6 mg, sodium carboxymethyl starch (sodium starch glycolate) - 38 mg, sodium lauryl sulfate - 10 mg, povidone - 10 mg, talc - 2.4 mg,
• kapole (paʻakikī, gelatin): titanium dioxide, gelatin, patent blue dye.

ʻO ka paona awelika o nā mea o nā kapoti he 240 mg.

Nā Papālā, 120 mg. 7 a he 21 paha. i loko o kahi pale polū i hana ʻia i ka film PVC a me nā konohiki i paʻi ʻia i ka alumini varnished.

1, 2, 3, 4, 6, 12 mau blisters ua kau ʻia i loko o kahi ʻeke o ka pepa.

Nā Kūpepa Nona 1 me ke kino a me ka pāpale uliuli.

Nā kiko o nā capsules: mau keokeo o ke keʻokeʻo a ʻokoʻa paha ke keʻokeʻo.

Lipase gastrointestinal lipase.

He haʻahaʻa loa ka puʻu kikowaena, 8 mau hola ma hope o ke kauā ʻana, ʻaʻole i hoʻololi ʻia ka Orlistat i ke anelepine (ʻo ka manaʻo ma lalo o 5 ng / ml).

ʻO ka paku ʻōpiopio o ka orlistat ka mea liʻiliʻi. Ma hope o ka nānā ʻana i ka 360 mg o ka leo radioaktif ua hōʻili ʻia i ka 14C-orlistat, ua hōʻea ka lele radioactivity i ka plasma ma hope o 8 mau hola, ua kokoke ke kikowaena o kahi orlistat ʻaʻole i hoʻololi ʻia a kokoke i ka palena o ka ʻike (ma lalo o 5 ng / ml). Ma nā haʻawina therapeutic, me ka nānā ʻana i ka hoʻonaninani no ka plasma manawanui, ʻaʻole i hoʻololi ʻia ka Orlistat i ka sporadically i loko o ka plasma, a he haʻahaʻa loa kona mau lohi (liʻiliʻi ma lalo o 10 ng / ml), me nā hōʻailona ʻole e hōʻuluʻulu ʻia, ka mea e kūlike me ka liʻiliʻi o ka hoʻopio ʻana o ka lāʻau lapaʻau.

Ma ka vitro, ʻoi paha ka mea orlistat ma mua o 99% i hoʻopaʻa ʻia i nā protein plasma, ʻoi aku ka nui o nā lipoproteins a me ka albumin. ʻO Orlistat ka minimally i komo i loko o nā kaila koko. Hoʻomili ʻia ia i ka pā o ka pā o ka gastrointestinal me ka hoʻokumu ʻana o nā metabolite i ʻole nā ​​ʻano pharmacologically M1 (hydrolyzed ʻehā līpone lactone ʻehā) a me M3 (M1 me ka pale o N-formylleucine mau koina). I kahi noiʻi i nā poʻe maʻi hānai e helu ana i ka 14C-orlistat, 2 metabolites, M1 a me M3, i helu no 42% o ka radioactivity plasma nui. Loaʻa ka M1 a me M3 i kahi apo beta-lactone wehe a hōʻike i ka hana hoʻoweliweli loa i nā lipases (hoʻohālikelike ʻia me orlistat, ʻo lākou ka 1000 a me 2500 mau manawa palupalu, kēlā). Hāʻawi ʻia i ka hana haʻahaʻa a me ka hoʻohaʻahaʻa haʻahaʻa o nā metabolites plasma (ma kahi o 26 ng / ml a me 108 ng / ml no M1 a me M3, kēlā, 2–4 mau hola ma hope o ka lawelawe ʻana o ka orlistat i nā pilala therapeutic), ua manaʻo ʻia kēia mau mea huakaʻi a i ʻole ka pharmacologically insignificant. ʻO ka metabolite nui ka M1 kahi pōpoki pōkole T1 / 2 (mau hola 3), ke kuhi ka lua o ka metabolite me ka wikiwiki (T1 / 2 - 13.5 hola). I nā poʻe maʻi luhi, ʻo ka Css o ka metabolite M1 (akā ʻaʻole ʻo M3) e hoʻonui i ka pā i ka nui o nā dosis o orlistat. Ma hope o ka hoʻomālamalama waha hoʻokahi o 360 mg o 14C-orlistat e nā mea maʻi me ke kino kino kino a ke kaumaha nei i ka momona, ʻo ka hoʻokuʻu ʻana i ka orlistat non-absorbable ma loko o nā ʻāpana o ke ala nui o ka maʻa. ʻO Orlistat a me nā metabolites M1 a me M3 ua hoʻopili ʻia hoʻi me ka bile. Ma kahi o 97% o nā waiwai i hoʻopaʻa ʻia e ka leo radioactly i hoʻopili ʻia me nā mea kuku, komo 83% - i loli ʻole.

ʻO ka nui o ka hoʻopā ʻana o ka wahine holoʻokoʻa i ka radioactivity āpau me 360 ​​mg o 14C-orlistat kahi i emi loa ma 2%. ʻO ka manawa no ka hoʻopauʻana me nā feces a me nā urine he 3-5 lā. Loaʻa nā hana i loaʻa ai ka orlistat i nā mea like me nā mea maʻi me ke kaumaha o ke kino maʻamau a me ka momona. Hoʻokumu ʻia i nā ikepili palena, ʻokoʻa mau ka T1 / 2 o nā orlistat ʻē aʻe ma waena o 1-2 mau hola.

ʻO kahi mea paʻa kūikawā o nā lipine gastrointestinal. Mālama ʻo ia i kahi pilina covalent me ka pae o ka serine ikaika o ka lipric a me ka pancreatic lipases ma ka lumen o ka ʻōpū a me nā ʻili liʻiliʻi. Ua aneane kekahi kaila eneuee i ka hiki ke wawahi i nā momona momona i ke ʻano o ka triglycerides (TG). ʻAʻole pākia nā TGs maikaʻi ʻole, a ʻo ka hopena o ka hōʻemi ʻana i ka calorie intake e alakaʻi i ka emi ʻana o ke kaumaha o ke kino. Hoʻonui ka hoʻonuiʻana i ka momona i nā hana 24-48 mau hola ma hope o ka nānā ʻana. Hāʻawi i kahi mālama pono o ke kaumaha o ke kino, hōʻemi i ka momona depot.

No ka hōʻike o ka hana, ʻaʻole pono ka ʻōnaehana o ka orlistat; ma ka ʻōlelo lapaʻau ʻia ʻoi ʻia (120 mg 3 mau manawa i kahi lā), ke pale ʻia nei ia i ka loaʻa ʻana o nā momona i loaʻa mai ka ʻai ma kahi o 30%.

E hoʻokuʻu i nā palapala a me ka ʻano

Kuhi i loko o kaʻaina i ke ʻano o nā capsules. ʻO ka papa hana kūpono he orlistat ma ka nui o 60 mg aiʻole 120 mg. ʻO ka mana hui nā sodium lauryl sulfate, microcrystalline cellulose a me povidone.

I ke kūʻai aku i ka lāʻau lapaʻau i ke ʻano o nā capsules, ʻo ka mea kanu ikaika he orlistat ma ka nui o 60 mg a i ʻole 120 mg.

ʻŌpala Gastrointestinal

I ka manawa pinepine ʻo ka ʻehaʻeha o ka ʻōpū, flatulence. Hiki i nā kulekele ke lilo i aila a hiki i kahi kūlana wai. Aia ka ōlo ʻana o ka pancreas, incontinence fecal.

Hiki i nā hopena ʻaoʻao - pinepine ke ʻeha o ka ʻōpū, flatulence.

Hoʻopili pū me nā lāʻau ʻē aʻe

Hiki i ka lāʻau lapaʻau ke lawe pū me nā lāʻau lapaʻaka hypoglycemia, akā hiki paha ke hōʻemi ʻia ka dosage. ʻOi aku ka maikaʻi ma ka lawe ʻana i ka cyclosporine a me ka hoʻomākaukau i ka waiora 2 mau hola ma mua o a i ʻole ma hope o ka lawe ʻana iā Orlistat.

Hoʻonui ʻo Orlistat i ka hopena o ka lawe ʻana iā Pravastatin. He hikiʻole ke lawe iā Acarbose a me Amiodarone i ka manawa like me ka lāʻau lapaʻau. Aia ka emi ʻana o ka kahe o ka prothrombin a me kahi hoʻololi i ka hōʻailona INR, inā ua lawe ʻia ka warfarin a me ka anticoagulants waha.

Hoʻolaha ka waipuna

Hiki i ke kōʻai me ka waiʻona ke hoʻonui i nā hopena ʻino mai ka gastrointestinal tract. Pono e haʻalele i nā mea inu wai i ka wā o ka lapaʻau.

Ma loko o ke kalapona hiki iā ʻoe ke kūʻai i nā huahana like ʻole no ka pohō kaumaha:

100% laha kaumaha me Xenical. ʻO nā makana mai kahi mea hānai meaʻai e pili ana iā Orsoten

Ma mua o ke kau hou ʻana i ka lāʻau lapaʻau me ka mea hoʻohālike, pono ʻoe e nīnau i ke kauka a loaʻa iā ʻoe kahi hoʻokolokolo. ʻO kēia mau lāʻau i ka contraindications a me nā hopena hopena.

Mea hana

Polpharma Pharmaceutical Plant S.A., Polani.

Lawe ʻia ka Cyclosporine i mau hola 2 ma mua a ma hope o ka lawe ʻana iā Orlistat.
Hiki i ka lāʻau lapaʻau ke lawe pū me nā lāʻau lapaʻaka hypoglycemia, akā hiki paha ke hōʻemi ʻia ka dosage.
Hoʻonui ʻo Orlistat i ka hopena o ka lawe ʻana iā Pravastatin.
Aia ka emi ʻana o ka kahe o ka prothrombin a me kahi hoʻololi i ka hōʻailona INR, inā hoʻokomo ʻia warfarin.
I loko o kahi lāʻau kūʻai, hiki iā ʻoe ke kūʻai i nā huahana me nā koina kaumaha like, e like me Xenalten.
He hikiʻole ke lawe iā Acarbose a me Amiodarone i ka manawa like me ka lāʻau lapaʻau.
Hiki i ke kōʻai me ka waiʻona ke hoʻonui i nā hopena ʻino mai ka gastrointestinal tract.

ʻO Anna Grigoryevna, kaukaʻi

Hoʻomaʻa ʻia ka lāʻau lapaʻau i ka hana o nā hoʻōla a me ka hoʻokeo ʻana i ka wai. No ka hoʻokō ʻana i ka hopena maikaʻi loa, e kuhikuhi ʻia nā mea maʻi i ka mea haʻahaʻa a me ke ʻano haʻahaʻa. Mai ka pēpē gastrointestinal, hiki mai paha nā hopena ʻino i nā manawa 2 mau pule mua, e nalowale ana i ka manawa. Aia kahi mea ponoʻole e lilo i mua o nā mea kūlohelohe i ka nui o ka momona (hormonal failed, tumors, inactivity, hypothyroidism).

ʻO Maxim Leonidovich, kaiʻai

Ua hōʻike ʻia ka lāʻau lapaʻau i nā mea maʻi no ka mālama ʻana i ka momona a me ke pale ʻana i ka loaʻa ʻana o ka hana nui. Ma hope o ka lawe ʻana i ka pōkole, ua emi kou makemake. Hiki ke lawe ʻia ka lāʻau lapaʻau e nā mea maʻi me ka diabetes mellitus type 2, hypertension a me ke kolamu kiʻekiʻe koko. Hōʻike ʻia e ʻai i nā mea kanu a me nā huaʻai, me ka inu a hiki i ka 2 lita o ka wai maʻemaʻe i kēlā me kēia lā.

ʻIke wau ua haʻalele koʻu mau hoa hana a me nā poʻe maʻi i nā loiloi maikaʻi e pili ana i ka lāʻau lapaʻau. Kōkua ka mea kōkua i ka nalo ʻana i nā paona keu. ʻO nā mea maʻi i loaʻa i nā hopena ʻaoʻao a i ʻole ua hōʻemi ʻia ka hoʻomaʻamaʻa maikaʻi ʻana i ka lāʻau lapaʻau.

Ma mua o ke kau hou ʻana i ka lāʻau lapaʻau me ka mea hoʻohālike, pono ʻoe e nīnau i ke kauka a loaʻa iā ʻoe kahi hoʻokolokolo.

Ua kauoha ʻia ka lāʻau lapaʻau no ka maʻi diabetes 2 ʻano. ʻO ka lāʻau palekana e hōʻemi i ke kaumaha o ke kino a hoʻomaikaʻi i ke kō koko. Lawe ʻo ia i ka lāʻau lapaʻau i hui pū me kahi meaʻai haʻahaʻa haʻahaʻa a me ke ʻano haʻuki. Ua hoʻomaka ʻo ia i ka maikaʻi, a ua hoʻomaka ka constipation me ka hopohopo. Ua nalowale wau he 9 kg ke hele nei wau e mālama i ka paona ma o ka lawe ʻana i kēia lāʻau lapaʻau.

ʻO nā hui, ʻike wau i ka hopena a me ka wikiwiki. Mai 75 kg, ua lilo iā ia ke kaumaha a 70 kg i 4 mau pule. Hōʻemi ka mea hana i ka momona, no laila, ʻaʻohe makemake e ʻai i nā meaʻai junk. E kōkua ka lāʻau lapaʻau i nā poʻe makemake e koi i ko lākou kino e ʻai i nā meaʻai maikaʻi. Hoʻokahi ka minus i ka ʻōpū. Hoʻomaka ka maʻi ʻana i nā lā mua o ka hoʻohana a mau i ka mahina.

Lawe au i ka lāʻau lapaʻau 1 ʻekolu mau manawa i ka lā. Hoʻomaka nā poʻo ma hope o ka lawe ʻana, ʻaʻole hiki ke hoʻokaʻawale ʻia me nā paila. Ke hebedoma ma hope iho, ua ʻike wau i ka ʻā ʻana o nā wāwae a me ke alo, nuea, ke ulu ʻana a me ka lolo. Loaʻa paha ka lāʻau lapaʻau e hōʻemi i ka paona, akā he mea maikaʻi loa ia no ke olakino. ʻAʻole wau e koi i ka lawe ʻana me ke koho ʻole ʻana i kauka.

ʻĀpana Pharmacological

Wahi a ke Kuhikuhi Kauka Kauka (2009)Orlistat i hōʻike ʻia no ka mālama ʻana i ka momona, incl. hōʻemi a me ka mālamaʻana i ke kaupaona o ke kino, i hui pū me ka meaʻai haʻahaʻa haʻahaʻa. Ua hōʻike pū ʻia ʻo Orlistat e hōʻemi i ka hopena o ka loaʻa hou o ke kino kino ma hope o kona emi ʻana i mua. Ua hōʻike ʻia ʻo Orlistat no nā maʻi hānai me ka index mass body (BMI; ʻike i "ʻikepili kūikawā" no ka helu ʻana) ≥30 kg / m 2 a i ≥27 kg / m 2 i mua o nā mea ʻē aʻe (ma ka maʻi maʻi, hypertension, dyslipidemia).

ʻŌpū a me ka lactation

ʻAʻole i mālama ʻia nā haʻawina kūpono o ka orlistat i nā wahine hāpai. ʻOiai ʻaʻole hiki i nā ʻikepili palapala manu ke hoʻoholo mau i ka pane ʻana i loko o nā kānaka, ʻaʻole i ʻōlelo ʻia ka orlistat no ka hoʻohana ʻana i ka wā hāpai.

Hana Hana FDA X.

ʻAʻole ʻike ʻia inā hūnā ʻia ʻo orlistat i loko o ka waiū umauma, ʻaʻole pono e hoʻohana ʻia i nā wahine hānai.

ʻO nā mea mālama palekana

Ma mua o ka koho ʻana i ka orlistat, pono e hoʻoholo ʻia nā kumu kūlohelohe, e like me ka hypothyroidism.

I ka manawa mālama, ua ʻōlelo ʻia kahi meaʻai haʻahaʻa haʻahaʻa haʻahaʻa, ʻo ia ka hāʻawi ʻana i nā momona i nā mea 30% o nā ʻoni. Hoʻopilikia ka hopena i nā hopena ʻaoʻao mai ka gastrointestinal tract me kahi koina o ka momona i ka meaʻai (ʻoi aku ma mua o 30% mau kaloli o kēlā me kēia lā). ʻO ka ke kau o ka lā i nā momona, nā pale a me nā ʻōleka e hoʻokaʻawale i waena o nā papa nui ʻekolu. No ka mea e hōʻemi ana ʻo orlistat i ka hoʻopili ʻana o kekahi mau momona a-momona o ka momona, pono nā mea maʻi e lawe i nā hoʻomākaukau multivitamin e loaʻa ana ka momona o ka momona o ka momona e hōʻoia i kā lākou ʻai kūpono. Eia kekahi, ʻo nā haʻawina o ka vitamina D a me ka beta-carotene ma nā maʻi hānai e haʻahaʻa e haʻahaʻa ma mua o nā poʻe i makemakeʻole i ka hina. Pono e lawe i ka Multivitamins i 2 mau hola ma mua a i ʻole 2 mau hola ma hope o ka lawe orlistat, no ka hoʻohālikelike ʻana, ma mua o ka hiamoe. Loaʻa ka loaʻa ʻana o ka orlistat i nā wai he keu o ka nui o 120 mg 3 mau manawa i ka lā ʻaʻole e hāʻawi i kahi hopena hou. I ka poʻe maʻi e lawe ana i ka orlistat a me ka cyclosporine i ka manawa like, e nānā pinepine ʻia ka nānā ʻana i ka cyclosporine plasma.

I ka poʻe maʻi i loaʻa ʻole i ka huaʻai me ka prophylactic supplementation, i ka wā o ʻelua a i ʻole ka holo hou ʻana i ke kauka i ka makahiki mua a me ka lua o ka mālama ʻana me ka orlistat, ua hoʻokaʻawale ʻia ka pae o nā waiora plasma i ka hapa o kēia mau hihia (nā hōʻike i ka pūʻulu plasebo i hōʻike ʻia i loko o kahi pala) 2% (1%), ka huaora D 12.0% (6.6%), ka huaora E 5.8% (1%), beta-karotiika 6,1% (1.7%).

I kekahi mau mea maʻi, e kū'ē ana i ke kua o orlistat, hiki ke hoʻonui i ka ʻikepili o nā oxalates i loko o ka urine.

E like me nā lāʻau'ē aʻe e hōʻemi i ka paona kino, i kekahi mau pūʻulu o nā maʻi (no ka laʻana, me ka anorexia nervosa a bulimia paha), hiki paha ke hōʻino hewa i ka orlistat.

Hiki ke hoʻohui pū ʻia ʻo Orlistat ka nui o ka hoʻolilo ʻana me ka metabolic control of diabetes mellitus, pono ia e hōʻemi i nā pehu o nā kuʻuna hypoglycemic oral (sulfonylurea derivatives, metformin, etc.) a i ʻole insulin.

ʻO ke kōkua kōkua i ka hakakā me nā paona ʻokoʻa. Hoʻolālā kālā kūlike ʻo Xenical a me Orsoten. E hana anei? - Ae!

Aloha ʻoe i nā poʻe a pau i nānā i ka loiloi!

Ua kamaʻāina pinepine au iā Orlistat lāʻau lapaʻau lōʻihi. I kekahi manawa, lawe ʻo ia i Xenical a me Orsoten, a ma nā kūlana ʻelua ua loaʻa i ka hopena. A laila aia kahi hoʻomaha lōʻihi i ka hoʻokomoʻana, e like me nā mea a pau i pili iaʻu, a laila hānau a me ka hānau keiki, umauma umauma a me kahi kau o 20 kg o ke kaumaha nui.

A pau kāna ʻai ʻana, hoʻoholo akula ʻo ia e hāpai iā ia iho, akā hele aku i ka hopena hewa, e like me kā lākou i ʻōlelo ai. Hoʻomaka me kahi punahele punahele, lohi i ka 6 kg a ʻai mau mea a pau i ka mau mahina ʻelua. Hoʻoholo wau i helu e helu i nā kaloli, akā mai ka hoʻomaka ʻana, kau wau i ka mea haʻahaʻa loa i kahi pākeke, ua loaʻa iaʻu kaʻai ʻana he 1200 Kcal. Ua piʻi kēia manawa i ka 1800-1900 Kcal. Akā e kūlohelohe iki ai wau. A no ka ʻaʻole ʻole e hāʻule i waho o nā kalatiha i hoʻonohonoho ʻia, ua hoʻoholo wau e kōkua iaʻu iho i ke kōkua o ka hoʻomākaukau ʻana o Orlistat. Ua kūʻai aku au i ka hapa nui loa o nā mea i loaʻa - ʻO Orlistat Akrikhin.

ʻO ke ʻano waiwai - Keʻokeʻo

Hoʻopuka ʻāina - ʻĀpana

Uila - 1930 rub. no na kapuai 84.

Inā ʻoe e helu nei i ke kumukūʻai o 1 capsule, akā ʻo ka uku kūpono loa e kiʻi ʻia i ke wā e kūʻai aku ai i kahi pahu nui (82 mau pūleka). 1 mau pahu hoʻoulu e pili ana i 23 mau rubles.

Loaʻa ʻia kekahi pūpū o 48 mau pālule. ʻO ia ka mea hana i hālāwai ʻole i ka pōpō i 21 mau kapeke, ʻo ia hoʻi ʻo Orlistatov iā ia.

Kahi wahi kūʻai - Lele lāʻau Stolichki

Nā kuʻina - Xenical, Orsoten, Listata.

ʻOhiʻohi pepa ʻalani ulaula.

I loko o 6 mau blisters no 14 mau kōlea.

Loaʻa nā lūlima he laina waimaka, no laila, inā pono, hiki iā ʻoe ke hoʻokaʻawale i kahi kīʻaha liʻiliʻi e lawe ai, no ka laʻana, me kahi kīʻaha a i ʻole e hana.

He uliuli nā pale kākele, āwelu i ka nui. ʻAʻohe pilikia i ka neʻe ʻana.

Nā ʻoslelo a me ke hoʻoponopono:

I loko, holoi a me ka wai, me kēlā me kēia papa nui (ma mua o ka ʻai, me ka ʻai a i ʻole ma mua o 1 mau hola ma hope o ka ʻai).

Hoʻolaha hana:

ʻO Orlistat kahi mea paʻa pono o nā lipine gastrointestinal lōʻihi. Hoʻohana ia i ka lumen o ka ʻōpū a me ka ʻili liʻiliʻi, ka hoʻopili ʻana i kahi paʻa covalent me ka ʻaoʻao o ka serine ikaika o ka lipric a me ka pancreatic lipases. ʻAʻole hiki i kahi mea e hiki ke hoʻonāukiuki i nā momona momona e hele mai ana ma ke ʻano o ka triglycerides i loko o nā ʻaina momona momona a me nā monoglycerides. ʻAʻole kope ʻia ka triglycerides e hoʻopono, a no laila e emi ke komo ʻana o ka nui o nā kalaleka ma ke kino, kahi e hoʻemi ai i ka paona kino.

Inā ʻoe e wehewehe i kahi ala maʻalahi, a laila ʻaʻole ʻae ka lāʻau lapaʻau e komo i kekahi mau momona a mākou e ʻai ai. A ua hoʻokaʻawale ʻia kēia mau momona momona me nā feces.

Hoʻohui wau e pili ana iaʻu iho inā inā ma loko o kekahi o nā meaʻai, ʻaʻohe momona, ʻaʻole pono e lawe i nā kapika. Inā mākou e ʻōlelo he ʻaina kakahiaka me ka oatmeal i loko o ka wai me nā hua, a laila ʻaʻohe māka o ka lawe ʻana iā Orlistat, ua hoʻohana mua ʻoe i kahi momona liʻiliʻi. Akā ʻo ka oatmeal, hoʻolapalapa i ka waiū me ka hoʻohui o kahi ʻāpana o ka pata, me kekahi mau ʻāpana o ke kao - he manawa kēia e lawe i ka capsule.

E like me nā lāʻau lapaʻau, ʻo Orlistat i loaʻa mau ʻōlelo hoʻohālikelike.

Hypersensitivity i orlistat a i ʻole kekahi o nā mea i hoihoi i ka lāʻau, maʻi malabsorption syndrome, cholestasis, hapai a me ka wā o ka umauma, nā keiki ma lalo o 12 mau makahiki o kona mau makahiki.

Me ka mālamaʻana: ka pilina concomitant me cyclosporine, warfarin, a i ʻole nā ​​anticoagulants waha. Hoʻohana i ka wā hāpai a me ka lactation: nā haʻawina preclinical i hōʻike ʻole i ka hopena teratogenic a me ka embryotoxic hopena o orlistat.Eia naʻe, ma muli o ka hapa ʻole o nā data lapaʻau e pili ana i ka hoʻohana ʻana i nā wahine hāpai, a ʻo Orlistat ka contraindicated ma ka hāpai ʻana. ʻO ka mea ʻaʻole i ʻike ʻia e hala ʻo Orlistat i loko o ka waiū umauma, ua pāpā ʻia i ka wā o ka umauma.

Hoʻololi wale ka papa inoa i ka hoʻohālikelike ʻia me nā nui ʻē aʻe.

Eia nō naʻe, aia kekahi mau moʻolelo ma ka Pūnaewele e hoʻopilikia maikaʻi ʻia ʻo Orlistat i nā nalo a me nā pōpoki. ʻAʻole wau e noho ma luna o kēia me ka kikoʻī, ʻoiai ʻaʻole i loaʻa iaʻu ka ʻike ma nā kumu kumu. ʻAʻole au i ʻike i nā kumuwaiwai o ka noiau e hana nei, akā ua hālāwai wale nō ka hana ʻana i kahi ʻatikala i ʻōlelo ʻia e ka noiʻi. Inā makemake ʻoe i kēia nīnau, a laila google e kōkua.

ʻO nā ʻōlelo ʻōlelo ma kēia kumuhana wale nō

ʻO nā hihia o ke kaʻe o ka rectal, diverticulitis, pancreatitis, cholelithiasis a me ka oxalate nephropathy i hōʻike ʻia (ʻike pinepine ʻole i ka ʻike ʻole ʻia).

I nā mea maʻamauka hopena ʻaoʻao o ka Orlistat pinepine me ka palalupalu i ka ʻaina, kū pinepine, bloating. Ma koʻu ʻāpana, e kapa wau i ka hopena o ka lawe ʻana i ka kākau wiwo ʻole. Ma hope o nā mea a pau, pono e hele i kahi momona ʻokoʻa. A he kūpono kūpono nā hopena āpau. Inā ʻaʻole ʻoe i ʻai i kahi lole hānai ʻona a ʻai i kahi ʻōmole momona, a laila e kali ʻoe no ka helu ʻana. Hāʻawi ʻia nā huakaʻi hele wāwae maʻamau i ka lua. Ma kēia e nānā pono ai ʻo Orlistat.

Lawe au i orlistat i kēlā me kēia manawa. E like me kaʻu i kākau ai ma ka hoʻomaka ʻana o ka loiloi, aia wau i kēia manawa i kahi kalaka liʻiliʻi ʻoi loa. ʻAʻole aneane nā meaʻai momona i kaʻu ʻai. ʻOi aku ka maikaʻi o kēia manawa, akā i kahi uku maʻalahi. Akā i kekahi manawa aia kahi kihi mai ka meaʻai. ʻO nā hoʻomaha, hui nui i nā hoaaloha i loko o kahi cafe, barbecue. A i ʻole hiki ʻole ke kaʻe iki mai ka nui o nā kaloli, ma ia mau mea e lawe ai au i ka kime Orlistat. ʻAʻole i like pinepine kēia i nā manawa 1-2 i ka hebedoma a ʻo ka hoʻokipa i ka maʻamau he hoʻokahi.

ʻO ka hana maikaʻi o ka lāʻau Orlistat Akrikhin he meaʻoi aku ka liʻiliʻi ma mua o ka makee o Xenical, uaʻikeʻiʻo wau i hope ʻoiai o nā hōʻuluʻulu ʻana. ʻO ka "helu" ʻano like ʻia i luna mai iaʻu.

ʻOiai ʻo ia ka ʻōlelo ʻana "Hoʻokaʻawale ʻia e ka laikini" ma kahi ʻeke, ʻoiaʻiʻo, ʻo ke kūʻai ʻana ma ke kīpeka me ka loaʻa ʻole o kahi loiloi ʻaʻohe pilikia. ʻAʻohe mea noi aku ma kahi kauka i noi aku ai.

ʻO ka ʻikepili, ʻaʻole ia he alakaʻi i ka hana, e kaʻana wale i koʻu ʻike. E hōʻoia ʻia a i ʻole ia, ua ʻoe iā ʻoe. I kekahi manawa, ua ʻōlelo ʻia e ke kauka. No kona kumu ua kūʻai au i ka ʻeke mua. Ua ʻike ke kauka i kaʻu mau hoʻāʻo a ʻike maopopo i ke ʻano o koʻu kino. ʻO ke kūpono, pono ʻoe e hana i kēia ma mua o ka lawe ʻana i kekahi lāʻau lapaʻau.

Mahalo i kou manaʻo i ka loiloi! Aloha ʻoe a me kāu poʻe aloha!