ʻO nā papa Ovencor: nā hōʻailona no ka hoʻohana, nā kumu kūʻai a me nā analog

Ariescore (nā pōpoki) Rating: 9

Mea Hana: Ozone (Russia)
Kuhi puka:

  • ʻLelo. 10 mg, 20 pcs., Kumukūʻai mai 372 mau rubles
  • ʻLelo. 20 mg, 20 pcs., Kumukūʻai mai 510 mau rubles
ʻO nā kumukūʻai ovenven ma nā māka kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

Hoʻomua ʻia ka lāʻau lapaʻau ma Rusia, i manaʻo ʻia no ka mālama ʻana i nā maʻi o ka ʻōnaehana cardiovascular. ʻO ka mea hana e simvastatin i ka nui o 10 a 20 mg no kēlā me kēia papa. Contected ma lalo o ke ʻano o nā makahiki 18.

Nā kuʻina o ka lāʻau lapaʻau ʻo Ariescor

ʻOi like ka analogi mai ka 313 mau rubles.

Mea Hana: Kūmole (Lūkia)
Kuhi puka:

  • Nā Papa 10 mg, 15 pcs., Kumukūʻai mai 59 mau rubles
  • Nā Papa 10 mg, 30 pcs., Kumukūʻai mai 62 mau rubles
Nā kumukūʻai Simvastatin i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Simvastatin kahi hopena lipid-hoʻokuʻu ʻana o ka hana maʻa Lūkia. Loaʻa ia i ke ʻano o nā papa a loaʻa nā ʻano hana like i loko o kahi waihona o 10 a 40 mg. Hoʻonohonoho ʻia no ka hoʻohana ʻana ma ka mālama ʻana i nā maʻi o ka ʻōnaehana cardiovascular.

ʻOi like ka analogi mai ka 173 mau rubles.

Mea Hana: Krka (Slovenia)
Kuhi puka:

  • Nā Papa 20 mg, 14 pcs., Kumukūʻai mai 199 mau rubles
  • Nā Papa 10 mg, 28 pcs., Kumukūʻai mai 289 mau rubles
ʻO nā kumukūʻai Vasilip i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO kahi mea e hoʻokomo maikaʻi aku ai i Slovenia me kahi ʻano like o ka hoʻokuʻu a me ka hoʻonohonoho o nā mea ikaika. ʻO nā hōʻailona nui no ka hoʻohana ʻana: hypercholesterolemia poʻo a me ka dyslipidemia i hui ʻia, kahi hōʻemi i ka make cardiovascular a me ka morbidity i nā mea maʻi me nā hōʻike olakino o nā maʻi atherosclerotic maʻi maʻi a i ʻole diabetes mellitus. Aia kekahi mau contraindications.

ʻOi like ka analogi mai ka 265 mau rubles.

Mea Hana: Gideona Haile (Romania)
Kuhi puka:

  • ʻLelo. 10 mg, 14 pcs., Kumukūʻai mai 107 rubles
  • ʻLelo. 10 mg, 28 pcs., Kumukūʻai mai 202 mau rubles
Nā kumukūʻai Simvastol i nā lāʻau kūʻai pūnaewele
Nā ʻōkuhi no ka hoʻohana

ʻO Simvastol kahi hoʻohālikelike o ka hana ʻana a Romana. Loaʻa i nā pepa kāleka o 14 a me 28 mau papa. ʻO ka mea ikaika e like me ka ʻaneʻi, no laila ua loaʻa nā ʻōlelo i ka hoʻohana ʻana i nā liʻiliʻi liʻiliʻi. Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, paipai ʻia mākou e kūkā i ke kauka.

E hoʻokuʻu i ke ʻano a me ka ʻano

Ka puka ʻana i hoʻokuʻu ʻia Ovenkor - nā papa i uhi ʻia: keʻokeʻo, keʻokeʻo biconvex (10 a 30 mau pcs. I nā poli, i loko o kahi pahu pahu o 10, 20, 40, 60, 80 a me 100 mau pā, 10, 14, 20, 28, 30, 40, 50 a 100 mau pcs. I loko o nā pahu pololi, ma kahi pūpū kāleka 1 pahu.

Helu 1 papa:

  • mea waiwai: simvastatin - 10 a 20 mg,
  • ʻO nā mea kōkua: polyethylene glycol-4000, talc, titanium dioxide, castor oil, butyl hydroxyanisole, microcrystalline cellulose, ascorbic acid, lactose, citric acid, mais a pregelatinized starches, magnesium stearate, hydroxypropyl methylcellulose.

Lapaʻau lāʻau

ʻO ka lāʻau mai ka pūʻulu o nā statins, he hopena lipid-hoʻēmi i ka palena HMG-CoA hoʻohiolo. ^ E Ha yM. Ua pani ʻia kona kūlana lactone kani, ka mea i hydrated i ke kino o ke kanaka, ʻo ia hoʻi, he prodrug.

ʻO ke apo Lactone nā kinikini kekahi i pili no ka ʻaina HMG-CoA hoʻohioloma muli o kahi mea e hoʻokūkū paʻa ai ia i kahi ʻāpana o ka receptor coenzyme Akahi e hoʻopili ai kēia enzyme.

ʻO ka mahele o ka molekine statin pili i ke kaʻina hoʻololi hômiaokilula i loko mevalonatee pili ana i ka huahana o ke kaʻikepili waena o kahi molowa kolamu. ^ E Ha yM. ʻO kēia mau kaʻina hana i kahi ʻano o nā hopena, e like me kahi hopena o ka ʻike intracellular kolamu hoʻemi a me ka wikiwiki o ka catabolism cholesterol LDL. ^ E Ha yM. ʻO ka hopena lipid-hoʻohaʻahaʻa i ka lāʻau lapaʻau ma muli o kahi e hoʻemi ʻana i ka nui o ka cholesterol ma muli o ka cholesterol LDL. ^ E Ha yM. I ka manawa like, kahi emi o ka pae o LDL dosis-hilinaʻi a he exponential.

ʻAʻole pili ka statins i ka catabolism a me ke kao o nā momona momona kūlohelohe, no laila e hoʻopiʻi i ka pae o TG kūlike (kekona). Wahi a nā noiʻi, hoʻonui ke lāʻau i ka pae o Hōʻikeʻike HDL a hiki i 14%. I ka hopena i ka hopena lipid-lowing, ka hopena i ka lāʻau maikaʻi i ka paia vascular i ka wā o ka endothelial dysfunction (kahi hōʻailona o ka preclinical manifestation o ka atherosclerosis awal), hoʻāla i ka waiwai o ka rheological o ke koko, a loaʻa kahi hopena antiproliferative a me antioxidant. ʻO ka hoʻomaʻamaʻa ʻia me ka lāʻau lapaʻau e ukali ʻia e ka emi o ka nui o nā maʻi cardiovascular.

Lapaʻau lāʻau

He nui ka absorption Simvastatin. ʻO ka pae kiʻekiʻe loa o ka plasma koko ma hope o ka hoʻolilo ʻana ua loaʻa ma hope o nā hola 1.3-2.4, ma hope o ka 12 mau hola hemo ia ma ka 90%. ʻO kahi kamaʻilio me nā protein plasma e pili ana i ka 95%.

Ua loaʻa ia i ka hopena o ka hopena mua ma o ka ʻūhā: hydrolysis me ka hoʻokumu ʻana o ka hua derivative beta-hydroxyacid, a me nā metabolites ikaika a me nā hana a puni.

ʻO ka hoʻopauʻana hapa-hapalua o nā metabolite ikaika he 1,9 hola.

Hoʻokuʻu ʻia ia ma ka helu nui o nā metabolites me nā feces (60%). I kahi hana hana ʻole, ma kahi o 10-15% kahi i hoʻopā ʻia e nā keiki.

Nā hōʻailona no ka hoʻohana ʻana

  • hypercholesterolemia: hypercholesterolemia maʻamau (type IIa a IIb) i nā mea maʻi me ka nui o ka loaʻa ʻana o ka hoʻoulu ʻana i ka atherosclerosis coronary i nā hihia o ka launa ʻana i ka papa ʻaina me nā haʻahaʻa haʻahaʻa a me nā hana lāʻau ʻole (hoʻemi kaumaha a me ka hana kino), ka hui pū me ka hypercholesterolemia a me hypertriglyceridemia, ʻaʻole i hoʻoponopono ʻia. a me nā hana pilikino,
  • IHD (ka maʻi naʻau coronary): e pale i ka myocardial infarction, hoʻemi ʻana i ka hōʻemi o ka maʻi cardiovascular (stroke a i ʻole ka lele ischemic attack), make, revascularization kaʻina, a me ka hoʻolohi i ka holomua o ka arteriosclerosis coronary.

Nā Hoʻohui

  • maʻi pūpū ma ka hana ikaika, he ulu mau ma ka hana o nā huina o nā huina o ka naʻau i ʻike ʻole ʻia,
  • porphyria
  • myopathy
  • makahiki i 18 makahiki
  • hapai a me lactation,
  • ka molowa ʻana o kēlā me kēia wahi o ka lāʻau, a me nā mea ʻala statin ʻē aʻe (HMG-CoA reductase inhibitors) i ka mōʻaukala.

Relative (ʻo Ovenkor i koho ʻia ma lalo o ka mālama mālama olakino):

  • inu nui
  • hypotension arterial, maʻi maʻi hopohopo nui, hopena endocrine / metabolic disorders, ʻōpala wai-electrolyte, hōʻeha, ka hōʻemi a ka maʻi (me ke dental) a i ʻole nā ​​kūlana ʻē aʻe i loaʻa ai kahi hoʻomohala o ka pilikia nui ʻole.
  • Nā kūlana ma hope o ka hoʻololi ʻana i ke kino i ka wā o ka immunosuppressant therapy (e pili ana me ka nui o ka pilikia o ka hiki ʻole o ka renal a me ka rhabdomyolysis),
  • epilepsy
  • ka hoʻoemi / hoʻonui ʻia ʻana o ke kiko o ka ʻāhui i ʻike ʻole ʻia.

Nā ʻōkuhi no ka hoʻohana ʻana iā Ovenkor: kaʻina a me ka maʻi

Lawe ʻia ka Ovencor i kahi manawa 1 i ka lā i ka ahiahi, holoi ʻia me ka wai nui. ʻAʻole pili pono ka manawa lawe i ka lāʻau lapaʻau me ka ʻai ʻana.

Ma mua o ka hoʻomaka ʻana i ka hoʻohana ʻana iā Ovenkor, ua kuhikuhi ʻia ka mea maʻi i kaʻai hypocholesterol maʻamau, e holo pono ai i ka pae o ka mālama ʻana.

Me ka hypercholesterolemia, ʻokoʻa ka pae o kēlā me kēia lā ma waena o 1080 mg.

ʻO ka paipai hoʻomaka ʻana no ka hypercholesterolemia he 10 mg. Ka palena - 80 mg o kēlā me kēia lā. Pono e hoʻololi ʻia nā ʻokoʻa (koho) o ka waʻa ma waena o 4 mau pule. I ka nui o nā hihia, ʻike ʻia ka hopena kūpono loa i ka wā e lawe ai i ka lāʻau lapaʻau i kēlā me kēia lā a hiki i 20 mg.

Me ka hypercholesterolemia hoʻoilina homozygous, e hāhai pinepine ʻo Ovencor i ka 40 mg i loko o ka 1 wai i ʻole a i ʻole 80 mg i nā wai 3 (20 mg i ke kakahiaka a i ke ahiahi, 40 mg i ke ahiahi).

ʻO nā hopena kūpono o Ovenkor no ka maʻi naʻau coronary a i ʻole ka hele ʻana o ka hopena koʻikoʻi o ka hoʻomohala ʻana, ʻo ia ka 20-40 mg i kēlā me kēia lā. I ka hoʻomaka ʻana o nā lāʻau, ʻo 20 mg ka hoʻokaʻawale ʻana, hiki ke hoʻonui ʻia i ke kala me kahi wāwahi o nā 4 wiki. A ʻoi aku ka liʻiliʻi o ka LDL ma mua o 75 mg / dl (1.94 mmol / L) a me ka nui o ka cholesterol ma kahi o 140 mg / dl (3.6 mmol / L), hoʻemi ka lāʻau.

In a maximum dosis o 10 mg, Ovencor i kuhikuhi ma lalo o 30 ml / min i nā mea maʻi me ka renal failed ʻole (CRF) (creinine clearance) a i hui pū ʻia me ka cyclosporine, danazole, gemfibrozil a i ʻole nā ​​fibrates (koe wale nō naʻe no fenofibrate), niacin i nā lipid e hoʻohaʻahaʻa i nā dosis ( a i ka 1000 mg i ka lā). Me ka hana like me ka amiodarone a verapamil paha, ʻaʻole pono ka nui o ka manawa o Ovenor e hoʻonui i ka 20 mg.

Nā hopena hopena

  • pānaʻi hana ia: ʻeha o ka ʻōpū, constipation / diarrhea, flatulence, nausea, pancreatitis, hepatitis, puʻu, hoʻonui ʻia ka hana ʻana o nā ate enzyme, phosphatase alkaline a me CPK (creatine phosphokinase).
  • nā ʻōhua nānā a me nā ʻōnaehana hoʻoweliweli: headache, asthenic syndrome, neuropathy peripheral, maʻi lahilahi, insomnia, paresthesias, hōʻehaʻeha o ka naʻau, ka hōʻino ʻana i nā leʻaleʻa o ka ʻono, nā hihiʻo blurred,
  • ka maʻi immunopathological a me nā maʻi: ke kāohi wela, eosinophilia, hyperemia o ka ʻili, ʻōpū, ka vasculitis, angioedema, polymyalgia rheumatism, thrombocytopenia, hoʻonui ESR, hōʻano hou i ka mea uluwau e like me ka maʻi, ʻūlū, urticaria, photosensitivity, pōkole o ka hanu,
  • nā umauma dermatological: loaʻa pinepine - dermatomyositis, ʻili kino, alopecia, kaʻeha,
  • musculoskeletal system: nāwaliwali, myopathy, nā ʻōpūʻī o ka naʻau, myalgia, jarang - rhabdomyolysis,
  • nā huaʻōlelo ʻē aʻe: palpitations, anemia, hoʻemi i ka potency, hoʻonā i nā hana renal.

Ke keu

ʻAʻohe mau hōʻailona kikoʻī o kahi overdose o Ovenkor (nā hihia o ka lawe ʻana i ka lāʻau lapaʻau ma loko o kahi hapa o 450 mg e ʻike ʻia).

Therapy: nā hana e ʻae ai i ka hoʻemi ʻana i ka hoʻowalewale o ka waiwai (ka hoʻohālikelike ʻana i ka luaʻi, ka lawe ʻana i ka charcoal hoʻāla), ka hana hōʻailona maʻi ma lalo o ka hoʻomalu a me ka hana hepatic, a me ka pae o ka CPK serum.

I ka hihia o ka hoʻomohala a me ka loaʻa ʻole o ka myopathy me ka rhabdomyolysis a me ka hoʻopololei o ka renal kūleʻa (ʻaʻole hewa ke kolohe, akā hiki ke hele mai i loko o kahi ʻano nui), wehe koke ʻia ʻo Ovenkor, ka hoʻomālamalama ʻana o ka diuretic a me ka sodium bicarbonate i hōʻike ʻia (e ka intravenous infusion). Inā loaʻa, hemodialysis e hana.

Hiki i ka Rhabdomyolysis ke hoʻoulu i ka hyperkalemia, kahi mea i hoʻopau ʻia e ka hoʻokele intravenous o ka calcium chloride a i ʻole ka gluconate calcium, ke kōpaʻa glucose i hui pū me ka insulin, mea kūʻai kalima, a mea paha, i nā maʻi koʻikoʻi, e ka hemodialysis.

Nā ʻōlelo kikoʻī

I ka hoʻomaka ʻana o ka hoʻōla, hiki ke ʻike ʻia kahi hala o ka neʻe ʻana i ka nui o nā enzyme o nā pēpē.

Ma mua o ka kuhikuhi ʻana i ka lāʻau lapaʻau a maʻamau mau i ka wā e hiki mai ana, pono e alakaʻi ʻia nā haʻawina o ka hana hepatic. ʻO ke alapine ʻana o ka nānā ʻana i ka hana o nā enzyme hepatic: nā mahina ʻekolu ʻekolu - kēlā me kēia 6 mau pule, a laila ma ka manawa o ke koena o ka makahiki mua - 1 mau manawa i nā mahina ʻelua, i ka wā e hiki mai ana - 1 mau manawa i nā mahina ʻeono. Hana ʻia nā hoʻokolohua kūpono e hoʻoholo ai i ka hana ate me ka nui o nā ʻōhua. Inā hoʻonui ʻia ka nui i ka 80 mg i kēlā me kēia lā, pono e hana ʻia i hoʻokahi manawa i kēlā me kēia ʻekolu mahina. Hoʻopaʻa ʻia ka Ovenkor i nā hihia o ka hoʻonui pinepine i ka hana transaminase (3 mau manawa i ka hoʻohālikelike ʻia me ke pae mua).

I ka wā hapai, ʻaʻole i loaʻa ka hopena nui no ka hoʻopau ʻia ʻana o nā lāʻau lipid-hoʻēmi i nā hopena o ka hoʻomohala ʻana i ka hopena o ka hypercholesterolemia mua.

ʻAʻole kuhi ʻia nā wahine o ka wā hānau keiki ʻaʻole i hoʻohana i nā contraceptives e lawe iā Ovenkor.

Me ka hoʻemi ʻana i ka hana thyroid (hypothyroidism) a i ʻole i ke hele ʻana i kekahi mau maʻi o ka maʻi (nephrotic syndrome) me ka hoʻonui ʻana o ka cholesterol, pono e mālama mua ʻia ka maʻi lalo.

Hiki ke alakaʻi iā Ovenkor i hiki i ke alakaʻi ʻana i ka myopathy me ka hopena o ka rhabdomyolysis a me ka pana ʻole ʻana.

I ka hanana ʻana o ka hōʻeha ʻole o ka naʻau, ka ʻehaʻeha o ka ʻōpū, nā ʻōpū palupalu a i ʻole ka luhilahi, pono ʻoe e ʻōlelo aku i kekahi kauka, ʻoiai inā ʻoe pū me ka maʻi a me ka malaise. Ke manaʻo nei / ʻaihue ʻana i ka myopathy, ua hoʻokuʻu ʻia ke ʻano.

E hōʻike i ka hanana o myopathy, ua ʻōlelo ʻia e ana pinepine i ka helu KFK. I ka hoʻohālikelike ʻana o ka maʻi ma hope o ka sternum, lawe i ka lāʻau lapaʻau e pono e noʻonoʻo pono.

Pono ka Aries i ke ʻano o ka monotherapy a ke hui pū ʻia me nā ʻōmole bile acid.

E hoʻoholo ke kauka i ka lōʻihi o ka mālama ʻana i kēlā me kēia.

ʻŌpū a me ka lactation

E like me nā kuhikuhi, ua contraindicated ʻo Ovenkor no nā wahine i ka wā o ka hāpai / lactation.

He palena liʻiliʻi nā hoʻomohala ʻana o nā mea pono ʻole o nā keiki hou i lawe ʻia e ko lāua mau maʻi i ka lāʻau lapaʻau. Pono nā wahine o nā keiki hānau keiki e lawe i ka simvastatin e hoʻohana i nā hana ulu. Ke hoʻohālikelike nei ka hānau keiki, hoʻopau koke ʻia ʻo Ovenkor.

Hoʻohui nūhou

  • erythromycin, immunosuppressants, telithromycin, clarithromycin, cytostatics, antifungal agents (ketoconazole, itraconazole), nefazodone, fibrates, hoʻōla o nikotinikika i nā wai kiʻekiʻe, nā proteides inhibitor: nui ka piʻi o ka myopathy,
  • danazol, cyclosporine, gemfibrozil a me nā fibrates ʻē aʻe (ke waiho ʻana i ka fenofibrate), niacin, amiodarone, verapamil, diltiazem: nā pilikia o ka myopathy / rhabdomyolysis,
  • anticoagulants waha (fenprocoumone, warfarin): nā kahe o ke kahe, ke nānā ʻana i ka coagulability o ke koko ma mua o ka hoʻōla ʻana a ua lawa pinepine ia i ka wā mua o ka hopena.
  • digoxin: hoʻonui i kona pae plasma,
  • colestipol, colestyramine: hoʻemi i ka bioavailability (hiki ʻoe ke lawe iā Ovencor 4 mau hola ma hope o ka lawe ʻana i kēia mau lāʻau, aʻo ka hoʻomohala ʻana o ka hopena hoʻohui).
  • waiʻuʻai huaʻai (ʻoi aku ma mua o 1000 ml i kēlā me kēia lā): nui ka hoʻonui nui ʻana i ka pae o ka hana o ka pale ʻana i ke kūkaʻi HMG-CoA i loko o ke koko koko (pono e ʻalo ʻia nā hui.)

ʻO nā hui o Ovenkor e: Simvalimite, Sinkard, Zorstat, Simvastatin, Holvasim, Simgal, Zokor, Simvor, Simlo, Vasilip, Simvastol.

ʻO ka wehewehe ʻana i ka lāʻau lapaʻau

Aries - He ʻaihue hypolipidemic mai ka pūʻulu o nā statins, kahi paʻa o ka HMG-CoA reductase. He prodrug, no ka mea he kaʻa lactone paʻa i kāna kulu, kahi i hoʻoliʻili ʻia ma hope o ke komo ʻana i ke kino.

ʻO ke ʻano o ke kaula stin lactone ka mea like me kahi ʻāpana o ka enzyme HMG-CoA reductase. E like me ke kumu o ka hoʻokūkū antagonism, nā molekini statin nakinaki i kēlā hapa o ka coenzyme A receptor kahi e hoʻopili ai kēia enzyme. ʻO kekahi hapa o ka molekine statin e pale aku i ka hoʻololi ʻana o ka hydroxymethylglutarate i mevalonate, kahi kikowaena o ke kō o nā molekole kolamu. Ke hōʻike nei i ka hana o ka HMG-CoA reductase e alakaʻi i kahi ʻano o ka hopena e pili ana i ka hopena, ka hopena ma kahi o ka hoʻohaʻahaʻa ʻana i ka maʻi koloka intracellular a me ka hoʻonui ʻana i ka hana o nā mea kū i LDL a, no laila, wikiwiki ka catabolism o LDL cholesterol (Xc).

Hoʻohui ka hopena hypolipidemic o nā statins i ka hoʻemi ʻana i ka pae o ka nui o ka kolamu ma muli o ka LDL cholesterol. ʻO ka emi ʻana o LDL he hilinaʻi i ka dosis a ʻaʻole i laina, akā exponential.

ʻAʻole pili ka poʻokela i ka hana o nā lipoprotein a me nā lipula hepatic, ʻaʻole i hoʻopilikia nui i ka synthesis a me ka catabolism o nā momona momona, no laila, ʻo kā lākou hopena ma ke kiʻekiʻe o TG ma ka lua a ma ʻokoʻa hoʻi ma o kā lākou hopena nui i ka hoʻohaʻahaʻa i ka pae LDL-C. ʻO ka hoʻohaʻahaʻa iki ʻana i ka pae o TG i ka wā o ka mālama ʻana me nā statins e pili pū ana i ka hōʻike o nā koena (apo E) i loaʻa i ka papa o nā hepatocytes i komo i ka catabolism o STD, aia ma kahi o 30% TG.

Wahi a nā noiʻi paʻa, hoʻonui ka simvastatin i ka pae o HDL-C i 14%.

I ka hopena i nā hopena lipid-lowing, ua loaʻa i nā statins ka hopena maikaʻi i ka hana endothelial (hōʻailona preclinical o ka atherosclerosis mua), ma ka paia vascular, kahi atheroma, hoʻomaikaʻi i nā waiwai rheological i ke koko, loaʻa nā antioxidant, nā waiwai antiproliferative. Aia kekahi hōʻike e hoʻomaikaʻi ai ka simvastatin i ka hana endothelial ma hope o 30 lā o ka lapaʻau.

Kahi ʻia ka hoʻohana ʻana o simvastatin me ka hoʻokaʻawale ʻana i ka manawa o ka maʻi cardiovascular maʻi, ʻoiai kahi o ka pae mua o LDL-C.

Kahi papa inoa o nā kūmole


E hoʻokuʻu i ke ʻano (ma o ke kaulana)Kūʻai, rub.
Aries
20 mg papa, 30 pcs.476
Avestatin
Actalipid
Atherostat
ʻLelo. 0,02 No. 30 (AVVA RUS OJSC / Sti - Med - Sorb OJSC (Rūsia)232
Tb PO 0.02 Helu 30 (ABVA RUS OJSC / Sti - Med - Sorb OJSC (Rūsia)232
Vasilip
Tabela 10mg N28 Vector (KRKA, dd. Wahi hou / pack. Vector (Russia)329.60
Papa 20mg N28 Vector (KRKA, dd. Wahi hou / pack. Vector (Russia)458.20
Tab 40mg N28 (KRKA - Rus LLC (Russia)628.20
Vero-Simvastatin
Zovatin
Zokor
10mg No. 28 tab (Merck Sharp a me Dome, UK. (England)176
Zokor Forte
40mg No. 14 tab (Merck Sharp a me Dome, UK. (ʻEnelani)458
Tab 40mg N14 (Merck Sharp a me Dome, UK. (ʻEnelani)519.90
Zorstat
SIMVAHEXAL
Kauka 20mg N30 (Hexal AG (Kelemānia)287.10
Tab 10mg N30 (Hexal AG (Kelemānia)319.10
Tab 40mg N30 (Hexal AG (Kelemānia)484.70
ʻO Simvakard
Tab 20mg N28 (ZENTIVA a.s. Czech Republic (Czech Republic)172
Tab 10mg N28 (ZENTIVA a.s. Czech Republic (Czech Republic)218.80
10mg No. 28 tab (Zentiva k.s. (Czech Republic)242
ʻO Simvacol
Simvalimite
Simvastatin
10mg No. 30 tab p / pl. (Borisovsky ZMP OJSC (Belarus)38.60
20mg No. 30 tab p / pl.o (Borisovsky ZMP OJSC (Belarus)47.50
Tab 10mg N30 Alsi (Alsi Pharma ZAO (Lūsia)53.70
Tab p / pl. About 20mg N30 Alsi (Alsi Pharma ZAO (Russia)54.50
20mg No. 30 tab p / pl.o AVVA RUS (AVVA RUS OJSC (Rūsia)68.30
10mg No. 30 tab p / pl.o (Ozone LLC (Lūkia)89.10
20mg No. 30 tab p / pl.o (Ozone LLC (Russia)113.80
Tab 20mg N30 (Verteks ZAO (Lūsia)147.60
Tab 10mg N30 (Verteks ZAO (Lūsia)207.30
Tab 20mg N20 (Hemofarm A.D. (Serbia)257.30
Simvastatin alkaloid
10mg No. 28 tab p / pl. (Alkaloid AO (Makedonia)59.80
Simvastatin Zentiva
10mg No. 28 tab (Zentiva k.s. (Czech Republic)259.90
20mg No. 28 tab (Zentiva k.s. (Czech Republic)335
40mg ʻAʻole. 28 tab p / pl. (Zentiva k.s. (Czech Republic)498.70
ʻO Pvizer Simvastatin
Simvastatin Sanofi
Simvastatin * (simvastatin *)
Simvastatin-ALSI
Simvastatin-SZ
40 mg papa, 30 pcs. (ʻIkaka Puhi, Rusia)91
Simvastatin-teva
Simvastatin-ferein
Simvastatin-Chaikafarma
Nā hale lole Simvastatin
Simvastol
Tab 10mg N28 (Gideona Richter OJSC (Ka Waiwai)197.10
ʻVorlelo ʻohu
Tab po 40mg No. 30 (Ranbaxi Laboratories Limited (India)60.10
Tab po 20mg N30 (Ranbaxi Laboratories Limited (India)282
ʻĀlelo Simgal
Tab 10mg N28 (Aivex Pharmaceuticals s.r.o. (Czech Republic)287
40mg No. 84 tab (Teva Czech Enterprises s.r.r.o. (Czech Republic)304.40
10mg No. 28 tab (Teva Czech Enterprises s.r.o. (Czech Republic)321.50
20mg No. 28 tab p / pl. (Teva Czech Enterprises s.r.r.o (Czech Republic)410
10mg No. 84 tab p / pl. (Teva Czech Enterprises s.r.r.o (Czech Republic)609.90
40mg No. 28 tab p / pl. (Teva Czech Enterprises s.r.r.o (Czech Republic)678
20mg No. 84 tab (Teva Czech Enterprises s.r.o. (Czech Republic)870
Tab 40mg N84 (Aivex Pharmaceuticals s.r.o. (Czech Republic)1505
Simlo
Tab 10mg No. 28 (Ipka Laboratories Limited (India)202.90
Tab 20mg N28 (Ipka Laboratories Limited (India)293.60
Hoʻohana
Kākaukau
Holvasim

Ua hōʻike aku kahi mea kipa i kahi lā pau

Pehea ka lōʻihi o Ovencor e manaʻo e hoʻomaikaʻi ka mea maʻi?
ʻO ka poʻe ʻikepili o ka noiʻi i nā hapa he nui ma hope o 1 lā i manaʻo ai kahi holomua. Akā ʻaʻole paha e kūpono kēia i ka manawa āu e hoʻomaikaʻi ai. E nīnau aku i kāu kauka no ka lōʻihi o kou makemake e lawe i kēia lāʻau lapaʻau. Hōʻike ka papa ma lalo nei i nā hopena o ka noiʻi ma ka hoʻomaka ʻana o kahi hana kūpono.
Nā lālā%
1 lā1

Hoʻokipa kekahi kipa i kahi manawa lohi

Pehea ka manawa e ʻoi aku ai e lawe iā Ovenkor: ma kahi ʻōpū ʻole, ma mua, ma hope o ka ʻai a me ka mea ʻai paha?
Hoʻike pinepine pinepine nā mea hoʻohana pūnaewele i ka lawe ʻana i kēia lāʻau lapaʻau ma ka ʻōpū ʻole. Eia naʻe, hiki i ke kauka ke ʻōlelo aku i kahi manawa ʻē aʻe. Hōʻike ka hōʻike ʻana i ka wā i lawe ai ke koena o nā mea maʻi i ka lāʻau lapaʻau.
Nā lālā%
Ma kahi ʻōpū1

He ʻumikūmālua mau malihini kipa i hōʻike mai i ke ahonui

Nā lālā%
> 60 mau makahiki12
70.6%
46-60 makahiki317.6%
30-45 mau makahiki2

Nā ʻōlelo kuhikuhi i ka hoʻohana ʻana

(Simvastatin) Ka helu helu inoa: LSR-002033/08
Inoa kālepa: Aries

ʻOiai inoa ʻole inoa honua: Simvastatin * (simvastatin *)

Pākuʻi helu: papa hana i ʻālani ʻia
Hōʻike: Aia i ka papa pākēnē kiʻi 1
mea ikaika: Ariescore - 10 mg a 20 mg,
nā mea hoʻowalewale: microcrystalline cellulose, lactose (waiʻa waiū), kōpuka pregelatinized (starch 1500), colloidal silicon dioxide (aerosil), acid ascorbic, butylhydroxyanisole, stearic acid, magnesium stearate, opadry II (polyvinyl alkohol, black polyglycol, iron gol talc, ka hao dye oxide yellow, iron dye oxide red, titanium dioxide).
ʻO keʻano: nā papa ʻaina biconvex, hoʻopuʻi i ka ʻoni, mai ke aniani i ke kukui polū me kahi kiʻi pinkish.
ʻĀpana Pharmacotherapeutic: agena lipid-lowing, HMG-CoA reductase inhibitor.
Pāʻālua ATX: C10AA01

Nā manaʻo hoihoi

Pehea e koho ai i ka analog kūpono
I loko o ka pharmacology, hoʻokaʻawale pinepine nā lāʻau i nā ʻ synlelo a me nā kikowaena. Hoʻokomo ʻia i ke ʻano o nā like o nā ʻano like ʻole i ke ʻano he hopena therapeutic ma ke kino. Ke hoʻohālikelike nei nā analogs i nā lāʻau lapaʻau e pili ana i nā ʻano like like ʻole, akā no ka mālama ʻana i nā maʻi like.

ʻO nā ʻokoʻa ma waena o nā maʻi a me nā maʻi bacterial
Hoʻopilikia ʻia nā maʻi maʻi e nā maʻi, nā maʻi, nā fungi a me ka protozoa. ʻO ke ʻano o nā maʻi i hoʻomake ʻia e nā maʻi a me nā maʻi like ʻole. Eia nō naʻe, ka hoʻokaʻawale i ke kumu o ka maʻi i ke koho e kūpono i ke ʻano kūpono e kōkua ai i ka hoʻokē ʻana i ka malaise a ʻaʻole ʻoe e hōʻino i ke keiki.

ʻO nā maʻi āpau ke kumu o ke anuanu pinepine
ʻIke kekahi poʻe i kahi kūlana i kahi pinepine ke keiki a a lōʻihi no ka manawa anuanu. Lawe nā mākua iā ia i nā kauka, lawe i nā hoʻokolohua, lawe i nā lāʻau lapaʻau, a ma muli o ke ʻano, ua hoʻopaʻa inoa ʻia ke keiki me ke keiki e like me ka maʻi nui. ʻAʻole i ʻike ʻia nā kumu maoli o nā maʻi ʻeha pinepine.

Urology: hana maʻi urethritis chlamydial
Loaʻa pinepine ʻia Chlamydial urethritis ma ka hana o kahi urologist. Hoʻokumu ʻia e ka intracellular parasite Chlamidia trachomatis, aia nō nā waiwai o nā huakini a me nā maʻi like, ua makemake pinepine i ka antibiotic therapy regimens no ka maʻi antibacterial. Hiki iā ia ke hana i ka mumū ʻole o ka maʻi o ka urethra i nā kāne a me nā wahine.

Ariescorp, palapala noiʻi (kumu a me ka uku)

Ma mua o ka hoʻomaka ʻana i nā maʻi me Ovencor, ua kuhikuhi ʻia ka mea maʻi i mea maʻamau kaʻai ʻai hypocholesterol. ^ E Ha yM. Pono ka lāʻau ʻālunu i ka manawa hoʻokahi i ke ahiahi, holoi ʻia me ka wai. Me ka hoʻokomo ʻana o ka meaʻai, ʻaʻole pono e pili pono ka lāʻau lapaʻau. Hoʻokumu ʻia ka dosis i kēlā me kēia lā no ka mālama ʻana hypercholesterolemia mai ka 10 a 80 mg. I kēia hihia, ʻo ka hopena mua he 10 mg. Hoʻololi ʻia nā loli hoʻohālikelike o nā hawewe i hoʻokahi mahina. I ka nui o nā maʻi, e kūpono ka hopena therapeutic hopena ma ka lawe ʻana iā Ovenkor i nā lā i kēlā me kēia lā a hiki i 20 mg.

No ka poʻe maʻi me Maʻi maʻi Ischemic a ʻo kona koʻikoʻi kiʻekiʻe o ka hoʻomohala ʻana i ka hopena kūpono o kēlā me kēia lā o ka lāʻau he 20-40 mg, a ʻo ka mea mua he 20 mg i kēlā me kēia lā. ʻAʻole hoʻokō ʻia ka hoʻoponopono ʻana no ka maʻi maʻi no nā maʻi ma hope o 60 mau makahiki o nā makahiki a me nā mea maʻi me ka haʻalulu hou ʻole a maʻalahi hoʻi. Me ka hoʻokūkū hoʻonohonoho ʻana o Ovenkoroma a Ierapamil a i ʻole Amiodarone ʻaʻole pono ʻoi aku ka nui o nā mahele o kēlā me kēia lā o Ovenkor ma mua o 20 mg.

Hōʻike, hoʻokuʻu i ke ʻano

Hoʻoikaika ʻo Ariescor he mākaukau monocomponent, ʻo ia hoʻi, hoʻokahi o nā mea kaha - simvastatin. ^ E Ha yM. Ke hana nei nā koena i kahi hana kōkua: hoʻolako i ka nui, hoʻomaikaʻi i ka hoʻohemo ʻana o nā papa, hoʻopaʻa pono i nā mea āpau a pau. I loko o kēia hoʻomākaukau, selulose, starch, ascorbic a me citric acid, magnesium stearate, titanium dioxide, wai momona (lactose), polyethylene glycol 4000, talc e hoʻohana ʻia no kēia mau kumu.

Nā Ariescor nā papa i loaʻa i ʻelua mauʻu - 10 a 20 mg paha. Ua puni lākou, matte, i uhi ʻia me ka lei keʻokeʻo.

Ka hana lāʻau lapaʻau

Hoʻokaʻawale ʻia nā papa o Ovenkor i mea huahana. ʻO ka molika simvastatin i ke ʻano o ka apo lactone. Kahi mea, ʻaʻole hiki ke launa pū me nā cholesterol mua. Akā ma nā puʻu, e hoʻolauna iā ia iho i ka loli kemu. ʻO ka ʻano hana simvastatin ka mea like me ka hoʻoneʻeʻana o ka hāmeʻa HMG-CoA, pono no ka synthesis o kolamu. Ma muli o kēia hoʻopunipuni, lawe ʻo ia i kona wahi i ka hopena kemu. ʻO kekahi hapa o nā molekue i kēia hihia e hoʻopili aku ai i ka hoʻokumu ʻana o ka mua o ka cholesterol. No ka mea, ua ʻemi ʻia ke ʻano o nā molekule.
Hōʻike ke kino i kahi hāʻule o ka cholesterol ma o ka hoʻonui ʻana i ka hana a nā mea LDL e hopu ana, e wikiwiki ana i ko lākou hōʻeha. ʻO LDL kahi momona "kino" e hāʻawi i ka hoʻokumu ʻana o nā waihona ma nā paia o nā moku koko. No laila, lawe i ka Ovenkor e hōʻemi i ka hopena o ka hoʻomohala ʻana i ka atherosclerosis.

E like me kekahi statins, ʻaʻole i pili ʻo Ovenkor i ka hana o nā enzyme e wāwahi i ka momona (lipases), synthes, a me ka wāwahi o nā momona momona o ka manu. No laila, ʻo ka hoʻokaʻawale ʻana i nā pae o nā momona kūpaʻa (triglycerides, TG) ka mea nui loa o ka hopena o ka hoʻōla ʻana o nā ʻāpana cell liver. Hāpai lākou i ka hoʻonāukiuki o nā lipoproteins palupalu waena, 30% ka haku o TG.

Ua hoʻāʻo ʻia ka hoʻohana ʻana o ka lāʻau lapaʻau Ariescor:

  • ka hopena pili i ke kūlana o ke kīʻaha o loko o nā moku koko (endothelium), nā paia o nā kīʻaha koko,
  • kaomi iki i ke kahe koko
  • he mau waiwai antioxidant
  • hoʻemi i ka hōʻeha o nā maʻi cardiovascular.

E like me nā kuhikuhi no ka hoʻohana ʻana me Ovenkor, he mea hoʻonui i loko o ka mokuʻāina o ka endothelium ma hope o kahi mahina o ka maʻi.

Hōʻike ʻia ka lāʻau lapaʻau e ka maikaʻi o ke komo ʻana. ʻO ka pae kiʻekiʻe loa i ke koko e loaʻa i nā hola 4 ma hope o ka hoʻoili ʻana o ka papa Ovenkor i ke kino. Hoʻomaopopo nā hoʻololi maikaʻi mua i nā pae kolamu ma hope o 2 mau pule.

ʻO ka hapa nui o ka simvastatin me ka bile e komo i loko o nā iwi, mai kahi kahi e hoʻopiʻi ʻia ai me nā feces. Hoʻokahi kahi ʻano hana o ka lāʻau lapaʻau ma ke keiki.

Pae kumu noi, dosage

Pono ke ʻano me ka Ovencor i kahi papaʻai ma mua o ka hoʻomaka ʻana i nā lāʻau, a ma ka papa o ke ʻano.

Kahi ʻia ka hopena o ka lāʻau lapaʻau ʻokoʻa. Manaʻo ʻia e hoʻomaka e hoʻohana i kahi liʻiliʻi liʻiliʻi, me kāna hoʻonui hou. Ua kākau mākou ma luna aʻe ua loaʻa ka hōʻemi nui loa i ka kolamu 28 mau lā ma hope o ka hoʻomaka ʻana o ka lāʻau lapaʻau. ʻO ia ke kumu i hoʻomaʻamaʻa ʻole ai nā hoʻoponopono hoʻololi pinepine.

ʻO ka ʻōnaehana hoʻomaka ʻia o Ovenkor e 5-20 mg / lā, a ʻo 40 ka nui / ka lā ka nui. No ka poʻe maʻi e lawe ana i ka immunosuppressants, hoʻohana ʻia ka simvastatin i ka nui o 5 mg / lā. Ma kahi hōʻeha renal koʻikoʻi, aʻo ke aʻo e hoʻomaka me ka hoʻomaka ʻana o 5-10 mg / lā.

ʻAʻole pili ka assimilation a me ka bioavailability o ka lāʻau i ke kino. Hiki iā ʻoe ke lawe ia ma mua o / ma hope o ke kau ʻana o ka ʻai, mai poina e inu i ka wai nui. ʻO ke koi koʻikoʻi: pono inu i nā papa i hoʻokahi lā i ke ahiahi.

Hoʻohui

Me ka hoʻokaʻawale ʻana o warfarin a me kekahi mau anticoagulants me Avencor, hoʻonui ʻia ka hopena o ka hopena o ka hopena. Hoʻolālā nō hoʻi ia i ka hoʻōho o ka ʻona ʻana i ka ʻāʻī, nā lāʻau lapaʻau e hoʻopilikia ai i kēia ʻili.

Ma muli o ka pilikia o ka rhabdomyolysis, ʻaʻole i ʻae ʻia ka hoʻohana ʻana i ka lāʻau.

  • a me ka keto, itraconazole, nā dosis kiʻekiʻe o ka vitamina PP,
  • nā kānaka e hoʻokomo ana i nā lāʻau lapaʻau immunosuppressive.

Ua paʻi nā kauka i kahi hihia o ka hoʻomaka ʻana o ka rhabdomyolysis ma hope o hoʻokahi kaha o nā simvastatin me ka sildenafil. Hoʻohana ʻia kēia lāʻau lapaʻau e hoʻoponopono i ka holo ʻana o ka erectile.

Nui ka hopena o ke kumukūʻai Ovenkor e ke kumu kūʻai. I nā kūlanakauhale a me nā lāʻau lapaʻau o Lūkia, he ʻokoʻa loa. No laila ke kumukūʻai o 10 mg hiki ke kumukūʻai mai 275 rubles, a me 20 mg dosis - mai 419 a 578 mau rubles.

I kēlā me kēia mau lāʻau lapaʻau hiki iāʻoe ke loaʻa nā analogues o Ovenkor - nā lāʻau lapaʻau me ka waiwai like ʻole, akā mai nā mea hana like. ʻO Simvastatin kahi ʻāpana o: Simvagesal, Zokor, Simvor, Simvakard, Simvastatin, Simvastol, Simgal, Simlo, Vasilip. Hoʻopiliʻia ke kumukūʻai, ʻokoʻa kēia mau lāʻau i nā ala kūpono. No ka laʻana, aia kekahi mau lāʻau me ka 5 a me 40 mg o ka mea ikaika. He kūpono kēia inā inā kau ke kauka i ke ʻano like me ia.

Nā mea i hoʻomākaukau ʻia e nā mea kākau o ka papahana
mamuli o ka palia hoʻoponopono o ke kahua.

Nā kumu kūʻai piha no Ovenkor

ʻOi like ka analogi mai ka 313 mau rubles.

ʻO Simvastatin kahi pōmaikaʻi maikaʻi loa Lūkini me ka like me ka mea hana pono i ka hoʻopili ʻana, akā ma kahi liʻiliʻi loa o 10 mg no kēlā me kēia papa. Ua kuhikuhi ia no ka hana ana o ka hypercholesterolemia a me ka hyperlipidemia lua. Hiki ke loaʻa ka papa inoa o nā hōʻike i loko o nā ʻōlelo kuhikuhi.

Simvastol (nā papa) Rating: 4 Top

ʻOi like ka analogi mai ka 265 mau rubles.

ʻO Simvastol kahi hoʻohālikelike o ka hana ʻana a Romana. Loaʻa i nā pepa kāleka o 14 a me 28 mau papa. ʻO ka mea ikaika e like me ka ʻaneʻi, no laila ua loaʻa nā ʻōlelo i ka hoʻohana ʻana i nā liʻiliʻi liʻiliʻi. Ma mua o ka hoʻomaka ʻana i ka mālama ʻana, paipai ʻia mākou e kūkā i ke kauka.

ʻOi like ka analogi mai ka 173 mau rubles.

ʻO kahi mea hou aku iā Ovenkor, ʻo ia ka mea i ʻoi aku ke ʻoi e ʻoi aku ka maikaʻi ma mua o ka "kumu" maoli, ʻoiai ʻaʻole ia i like ka ʻokoʻa. Contraindicated ma ka hāpai ʻana, lactation a ma ke wā kamaliʻi. Hiki ke loaʻa ka papa inoa o nā contraindications i nā ʻōlelo kuhikuhi.

Waiho I Kou ManaʻO HoʻOpuka