Neurontin: nā ʻōlelo no ka hoʻohana ʻana i nā papa a me nā ʻoki

ʻO ka lāʻau lapaʻau kekahi o nā anticonvulsants. Mahalo i ka hoʻohana ʻana iā Neurontin, hiki iā ia ke ʻae i ka ʻeha i kū mai ma luna o ke ʻano o ke ala o ka neuropathic pathology.

Ke hōʻike ʻia nei ka hoʻohana ʻana i ka lāʻau Neurontin no:

ʻO ka hōʻeha ʻana o nā maʻi neuropathic koʻikoʻi (ua hōʻike ʻia ka lāʻau lapaʻau no nā kānaka ma luna o 18 mau makahiki)
ʻO ka lapaʻau no nā kuʻuna hāpau, me ka ʻole o ka hoʻonui ʻana o ka male (i ʻōlelo ʻia no nā keiki mai 3 mau makahiki o ka hoʻōla paʻakikī, hiki i ka maʻi monotherapy mai nā makahiki 12)

Nā hoʻonohonoho hoʻonohonoho a hoʻokuʻu i nā palapala

Aia nā papa neurotin i hoʻokahi papa hana, ʻo ia ʻo gabapentin, ʻo kona nui ma ka 1 pill ka 600 mg a me 800 mg. Wahi a ka wehewehe kā lākou:

Copovidone
Stearic Acid Mg
ʻO ka pauma Talcum
Wili poli
Poloxamer
Mōʻī
Hulu ka cellulose Hydroxypropyl
Keokeo keʻokeʻo.

I nā kāpena i ka gabapentin i loko o kahi waihona o 100 mg, 300 mg a 400 mg. Hoʻokomo nā mea hoihoi:

Ke keʻokeʻo nā kapala (dosage 100 mg), ka melemele (ka nui 300 mg), a me ka hina-ʻulaʻula (dosage 400 mg). I loko o kēlā me kēia kapili kahi kikoʻī o ka pauka keʻokeʻo. Hoʻokomo ʻia nā kōpū i kahi kōpili o 10 pcs., He 5 a he 10 paha blisters i loko o ka pā.

Hoʻopili ʻia nā pailiona keʻokeʻo i loko o kahi pūʻulu blister o 10 mau p., Ka waihona ka waihona i 2, 5 a i ʻole 10 mau palepona.

Hoʻomaopopo i nā waiwai

Hoʻopili koke ʻo Gabapentin i ka hohonu o ka lolo, e pale i ka hōʻeha ʻana o ke ʻano hoʻomālamalama i kekahi mau ʻāpana o ka epilepsy. Hoʻohālikelike ka waiwai hana e kahi pilina no GABA receptors o GABA a ʻaʻole i hoʻopilikia i ke ʻano o ka hoʻololi ʻana o ka metabolic o GABA. He mea pono ia ʻaʻole e launa pū ka mea ikaika o Neurontin me nā mea hoʻoponopono o nā ʻano like ʻole o ka neurotransmitters e kū nei i loko o ka lolo a ʻaʻole i hoʻopilikia pololei i nā pāsa sodium.

Pili ʻo Gabapentin me ka subunit o ka lālani calcium-gated o α-2-δ, e like me kekahi mau hōʻike, ʻo ia ka mea e hāʻawi ai i ka hopena anticonvulsant i hoʻohālikelike ʻia a me ka wehe ʻana o ka ʻeha neuropathic.

Me kēia, ua hōʻemi ia i ka nui o ka make o ka cell cell glutamate-hilinaʻi, ke hāʻawi nei i ka hoʻonui i ka hoʻokumu ʻana o GABA, ka mea e alakaʻi ai i ka hoʻoemi o ka hoʻokuʻu ʻana o nā neurotransmitters lākou iho, ka mea i hoʻopili i ka hui monoamine.

ʻO ka mākaʻikaʻi bioavailability kiʻekiʻe kahi e pili ana i ka 60%; ʻo kona piʻi ʻana me ka piʻi ʻana o ka hopena o nā lāʻau lapaʻau. Hiki ke piʻi aku ka nui o ka plasma kiʻekiʻe ma hope o nā hola 2-3 ma hope o ka inu ʻana o nā paila. Ua hōʻole ka hui o ka gabapentin me nā protein plasma (e pili ana i 3%).

ʻAʻoleʻoi aku ka hapalua o nā manawa iʻoi aku ma mua o 7 mau hola, ʻoiai he nui nā wai e lawe ai i ka lāʻau lapaʻau. Hoʻopili ʻia ka lāʻau lapaʻau i kāna ʻano kumu me ka komo ʻana o ka ʻōnaehana renal.

Neurontin: nā ʻōkuhi piha no ka hoʻohana

ʻO ke kumu kūʻai o nā papa: mai 1125 a 1898 mau rubles. ʻO nā kumukūʻai no nā kapsul: mai 902 a 1629 mau rubles.

Pono ʻia ka lāʻau lapaʻau e inu i nā wā ʻai a ma hope.

ʻO nā kumumanaʻo o ka maʻi ma nā pākeke ke hihia o ka hōʻeha ʻeha o ka neuropathic:

ʻO kahi lā 1 - kahi hoʻohana hoʻokahi o nā lāʻau lapaʻau i loko o kahi iniha o 300 mg
2 lā - ʻāpono ʻia e inu i ka 300 mg o ka lāʻau i ʻelua mau lā i ka lā
3 lā - ka hoʻokipa ʻia ʻana o Neurontin 300 ʻekolu mau manawa i ka lā i hōʻike ʻia, i kekahi mau mea hiki ke hoʻohana i kēia ʻano o nā lāʻau lapaʻau mai ka hoʻomaka ʻana o ka hopena.
Ma kahi o ka hana o ka wā - e kau ʻia ke ʻano o ka ʻai ʻana o Neurontin i ka hopena therapeutic i nānā ʻia a me ke ʻano maʻamau o ka mea maʻi, e waiho ʻia ana ka nui o ka lāʻau a piʻi (kiʻekiʻe loa ke ʻano o ka lā kau i nā lā he 3.6 g).

Koho ʻia ka hopena o ka lāʻau i ka wā o ka therapeutic therapy ma mua o nā puʻu māhele i nā poʻe i ʻoi aku he 12 mau makahiki he nui e like me ke kumu i hōʻike ʻia ma luna nei. I mea e pale ai i ka hoʻomau hou ʻana o ka maʻi nanamana, pono ʻoe e lawe i nā capsules a i ʻole nā peni me kahi manawa o 12 mau hola.

Ke kau ʻana i ka lāʻau lapaʻau i nā keiki 3-12 mau makahiki me nā neʻe hapa.

Ka helu helu ʻana ma ka paona
Mai ka lā 1 o ka papa hana, he hoʻohana triple i ka lāʻau lapaʻau me ka manawa manawa e ʻaʻole iʻoi aʻe ma mua o 12 mau hola i hōʻike ʻia
ʻO ka dosent i kēlā me kēia lā i ʻōlelo ʻia ʻo 10-15 mg no 1 kg
I loko o nā lā ʻekolu mau lā, hoʻonui ʻia ke ʻano o nā lāʻau lapaʻau me ka maikaʻi loa
Ke hōʻike ʻia nei ka nui o ka lāʻau i kēlā me kēia lā no ka pēpē: no nā pēpē 3-5 mau makahiki he 40 mg i ka 1 kg, mai 5 a 12 paha makahiki, ke ʻano o ka 25-35 mg o nā lāʻau lapaʻau ma ka 1 kg e hōʻike ʻia.

I ka hihia o nā hana renal impaired, a ʻoi ʻia e hōʻemi i ka palena maʻamau o Neurontin. I ka wā e koho ai i ka hāmeʻa pono, pono ia e noʻonoʻo pono i ka hoʻomāliʻina hana loea.

Ma hope o ka hoʻopau ʻana i ka mālama ʻana, pono ʻoe e nānā i ke ʻano maʻamau a laila ke hōʻoia ʻo ke kauka e ola ʻiʻo nō ʻoe.

Nā Kūlana a me nā Mākaʻi

ʻAʻole ia e hāʻawi i nā lāʻau lapaʻau e pili ana i ka gabapentin no:

Keiki (o ke keiki ma lalo o 3 mau makahiki)
Loaʻa o ka hoʻonāukiuki nui loa i ka māhele nui.

Me ka mālama aka, pono e hoʻokō ʻia ka mālama ʻana i ka poʻeʻelemakule a me nā mea maʻi me nā ala poloka.

I ka wā o ka hoʻokele ʻana o nā capsules a me nā papa o Neurontin, ʻaʻole i hoʻopaʻa ʻia ka hoʻomohala ʻana o ka maʻi withdrawal me ka hanana aʻe o ka maʻi convulsive. ʻOiai ʻo kēia, ka hoʻopau koke i ka mālama ʻana me nā lāʻau anticonvulsant i loko o nā mea pilikino me kahi puʻuwai ʻāpana e alakaʻi i ko lākou helehelena.

Pākuʻi ʻia nā kapakai i ka lactose, no laila ʻo ka poʻe me ka congenital malabsorption syndrome, intolerance galactose, a me ka hemahema o ka lactase ʻaʻole lākou e lawe.

Nā pili kūleʻa lāʻau

Ke lawe nei i ka morphine (ua lawe ʻia kēia lāʻau lapaʻau ma kahi o 2 mau hola ma mua o ka hoʻohana ʻana iā Neurontin), he piʻi nui loa ka piʻi ʻana o ka gabapentin e like me 44% ua hoʻopaʻa ʻia i hoʻohālikelike ʻia me ka monotherapy me Neurontin. ʻO nā hopena ʻino e pili ana i ka morphine me ka hoʻohana pū ʻia ʻana o nā mea hana e pili ana i nā gabapentin, ʻaʻole ia i hoʻokaʻawale ʻia me nā mea i hoʻopaʻa ʻia me ka hoʻohana ʻana i ka morphine a me ka placebo.

ʻAʻohe hopena maikaʻi ʻole o nā lāʻau lapaʻau e pili ana i ka waima valproic, phenobarbital, carbamazepine, a me ka phenytoin.

Ke lawe nei i COC, me ka norethindrone a ethinyl estradiol, ʻaʻohe loli i loko o nā pharmacokinetics o kēlā me kēia lāʻau lapaʻau.

I ka wā o ka mālama ʻana me nā antacids, e komo pū ana me Al a me Mg, ʻo ka bioavailability o ka gabapentin pono e pili ana i ka 20%.

Nā hopena ʻaoʻao a me ka overdose

I ka wā e mālama ai me Neurontin, hiki ke hoʻopaʻa ʻia i nā hōʻailona like ʻole:

Noho kue
Ka haunaele
Lākina ʻole o ka maloʻo
ʻEha i ka ʻōpū a me ke kua
Haki i loko o Gastrointestinal
Nā poʻokela ʻeha
ʻO ka hoʻomohala ʻana o ka maʻi pāʻai a me ka maʻi maʻamau
ʻO ka hopena nui o ka puffity peripheral
Ihu holohe
Hoʻololi maikaʻi
Hoʻopili iki i ka hanu
ʻIli ka ʻili
Pharyngitis, bronchitis
Hoʻololi ke kauka
ʻEhaʻeha
ʻO ka hopena nui o ka hypersthesia.

Ua ʻike pinepine ʻole ʻia:

Nystagmus
Polika
ʻO ka haunaele hiamoe
Ke hoʻomaʻamaʻa ʻana o kekahi mau ʻoliʻoli
Tremor
ʻO ka puka mai ana o ka hana naʻau
Nā hōʻailona o ka asthenia, ataxia
Hoʻohuiwi i ka noʻonoʻo
Hōʻāwalu huehue
Hyperkinesia
Amblyopia
Ke Hoʻoulu a amnesia
Pololika

Ke lawe ʻia ka nui, hiki ke mālama ʻia ka hoʻomohala ʻana o nā ʻōuli like:

ʻ speechlelo iki hoʻi
ʻEha hōʻeha koʻikoʻi
ʻO ka hiamoe nui
Hoʻopiʻi ʻike ʻia
Nā maʻi maʻi.

A ʻoi ʻia e lawe i nā hana i manaʻo ʻia e hoʻopau i nā hōʻailona i nānā ʻia. Ma kahi o ka ʻōnaehana renal impaired, hiki ke kuhikuhi ʻia kahi kaʻina hemodialysis.

Inā pono, hiki i ke kauka ke ʻōlelo aku iā ia e hoʻololi i Neurontin me nā analogue. Hōʻike ʻia nā papa, nā kapapena (nā lāʻau lapaʻau me kahi hopena like) e like me ke ʻano hana i koho ʻia e ia.

ʻO Artesan Pharma

Kūʻai mai 352 a 1127 mau rubles.

Ke ʻano lāʻau i hōʻikeʻia e ka hopena antiepileptic. Hoʻomaopopo ʻia e lawe aku i ka hoʻokaʻawale ʻāpana i nā keiki mai 12 mau makahiki a me nā pākeke, he maikaʻi ia i ka ʻeha, nā mea i kūkulu ʻia ma muli o ka neuralgia, neuropathy. ʻO ka waihona kūpono kahi gabapentin. Loaʻa ma ke ʻano o nā kapapena me kahi kaha o 100 mg, 300 mg a me 400 mg.

NOHO