Atorvastatin: nā ʻōlelo no ka hoʻohana ʻana a me nā loiloi o nā cardiologists

ʻAʻole wau i ʻike i kahi holomua, akā kahi poʻo, hōʻeha a me ka hiamoe. He aha kā mākou "Botany" e kōkua mai i ka poʻe, a ʻaʻole pū kekahi)

Hoʻonohonoho ʻia e lawe i ka atorvastine me ka kolamu 6. 5. Ua inu wau i ka 10 mg i kēlā me kēia lā - ʻaʻole wau ʻike i ka hopena kūikawā, akā he nui nā hopena kūpono. Ke hoʻāʻo nei wau e hoʻololi i kahi ʻai.

ʻAʻole au e ʻōlelo he ʻano kupaianaha kēia lāʻau lapaʻau. Ua kuhikuhi ʻia i koʻu makuakāne ma kahi o 60 mg / lā, no ka mea, he kolamu kiʻekiʻe kona kuʻuna i ka ʻohana.

• ʻoluʻolu o ke komo ʻana (me ka manaʻo o ka intake meaʻai).

• ʻAʻole wau i ʻike i kahi loli i ke olakino ma ka hopena o ka mālama ʻana. ʻOi aku ka nui o ka kolamu ma mua o 7 mmol / l, ua waiho ʻia ma hope o hoʻokahi mau mahina, ua pāpā ke kolamu o kona makuakāne i ka popliteal artery, ka mea e hoʻonāukiuki i ka nekrosis o ka manamana wāwae nui. Ano, i mea e pale aku ai i ka amputation palua i hoʻokahi makahiki, ua hoʻohui ʻia nā kūpuna me nā lāʻau lapaʻau loa.

I koʻu manaʻo, he lāʻau lapaʻau maikaʻi ʻole ka atorvastatin, ʻaʻole wau i ʻike i ka mea a nā kauka i kuhikuhi ai no ia.

Ua kuhikuhi ʻia ʻo Mom Atorvastatin ma hope o kahi hōʻeha. Ma mua o kēlā, ua lawe ka makuakāne i nā lāʻau lapaʻau no ka kolamu kiʻekiʻe, akā paʻa loa nā mea āpau ma mua o 1000r. I kēia hihia, makemake nui ke kumukūʻai. Akā hoʻokahi wale nō kēia no ka makuahine.

Ma hope o 3 mau mahina o ka lawe ʻana i Atorvastatin, ʻaʻole i emi ka cholesterol. E kūʻē i ke kiʻi ʻana o ka lawe ʻana i nā pilama, hōʻeha a me ke kuʻuna. ʻAʻole naʻe he kumu ka nui o nā ʻōkuhi i ka nui o nā hopena o ka ʻaoʻao, i loko o kēia lāʻau e manaʻo ʻia no ka poʻe ʻelemakule. A he makuahine makua ko koʻu makuahine. ʻAe, a me ka cholesterol kiʻekiʻe e pili pū i ka makahiki o nā kānaka.

Ua noi lākou i ke kauka e kāpae i ka lāʻau lapaʻau, ʻaʻole lākou e ʻae iā lākou, ʻōlelo lākou e pono e lawe i ka manawa, a ʻaʻole lākou e ʻōlelo. No laila, e hoʻopau ʻoe iā ia. ʻAʻole maʻoluʻolu ka hoʻomaʻamaʻa ʻana, a ʻaʻohe ʻano o ke alakaʻi ʻana ke ola.

• mau hopena ʻaoʻao

Makemake wau e kamaʻilio e pili ana i kekahi ʻike leʻaleʻa, ka ʻike i ka hoʻomaikaʻiʻana i kaʻu kolamu ma ke koko. Pēlā i ʻike nui ai koʻu kolamu ma mua o ka mea maʻamau, ʻaʻole nō wau i hoʻāʻo ʻē iā ia, a loaʻa wale lākou iaʻu ma ka haukapila.

I ka pōkole, ua ʻōlelo ke kauka i ka hoʻohaʻahaʻa ʻana ia, ʻoiai ʻo ke kolamu kiʻekiʻe, huli ia, pōʻino. Ke hoʻohaʻahaʻa nei, nā meaʻaiʻai. Ma hope o ka pau ʻana o ka loiloi, ua hoʻohuli ʻia ʻoi i lalo i ko lalo. E hoʻonui i ka hopena, ua kuhikuhi mai ke kauka iaʻu i ka lāʻau "Aorvastatin". Ok, ke ae nei au, i ka wā pāʻina. Ma hope o kekahi mau lā hoʻokipa ʻana, manaʻo ʻia ua like me kahi pūnao ahi i loko i loko oʻu. ʻAʻohe leʻa ʻole, kahi mea i ʻike ʻole ʻia i loko o ka ʻōpū.

Ma hope o hoʻokahi pule o ka ʻeha, ua naʻauao wau e heluhelu i nā loiloi a ʻaʻole wale ma luna o ko Otzovik, a laila ʻike wau ua hele mai kēia mea iaʻu. Hoʻopau koke aku ʻoe i nā mea a pau a hoʻomaka ke ola. ʻAʻole wau i pilikia i ka ʻōpū, no laila ʻaʻole hiki iaʻu ke noʻonoʻo pono i ke ʻano o kēia mau lāʻau i ka poʻe i loaʻa kēia mau pilikia.

ʻOiaʻiʻo, ʻokoʻa mākou a pau, "he mea maikaʻi ke make no ka Lūkini-Kelemania," akā ke manaʻo nei au inā pono ʻoe e hoʻokumu i kekahi mea ma ke kino i ke ʻano kūlohelohe, no laila e ʻoluʻolu, e hele i ka mea ʻai, e ʻai i nā mea ʻai, a me nā huaʻai, pāʻani i nā haʻuki.

ʻAʻole wau e aʻo i nā hoaaloha, he "infernal nā papa."

ʻAʻole wau e aʻo i ka hele ʻana iā lākou

Atorvastatin ʻO wau iā 1, 5 mau makahiki. Hoʻomaʻamaʻa ʻole ʻia ʻo Cholesterol. Ua lilo ʻo 4, 6 i mau 4, 4. He mea kūpono paha e hoʻouka i kou palaka inā ʻaʻole pono ka lāʻau lapaʻau. I ka mua ua lawe wau i 20 mg, a laila hoʻonui ke kauka i ka maʻi i 30 mg.

ʻO kekahi helu nui o nā hopena ʻaoʻao. Me koʻu puʻupuʻu, nui ke kaumaha i loko o koʻu poʻo, ma hope o ka hebedoma e komo ai, ua hiki mai kekahi pōpilikia: ʻoi ʻia ka popo i kahi nui ʻana e kāhea aku ai i kahi kīkoʻi, ʻaʻole i hana mua iaʻu. Aia ka luaʻi, hoʻonui ʻia ke kaumaha (a ʻaʻole wau e ʻeha i kēia mai kēia manawa), aneʻane loa like me ka ʻike ʻole. Lawe lākou iaʻu i 1st Gradskaya, hana i kahi scan ʻo CT, he cardiogram, a me ka hoʻāʻo koko. ʻAʻole i loaʻa iā lākou kekahi hewa, ua hōʻike kā lākou me ka discirculatory encephalopathy a hoʻouna iā lākou i ka home. ʻĀnō, ua heluhelu hope wau i nā ʻōlelo kuhikuhi a loaʻa iaʻu kaʻu mau hōʻailona i ADVERSE EFFECTS. He aha hoʻi kaʻu e kū ai?

Heluhelu i ka puke holoʻokoʻa holoʻokoʻa. Hoʻomaopopo nā kauka e pili ana i nā hopena hiki.

Ua hana ʻo ia i kahi maʻi kino a hōʻike ʻia i ke kolala kiʻekiʻe - 7, 6. Ua kuhikuhi ke kauka i ka atorvastatin 1 papa ma kēlā me kēia lā. He mea pono ke kāhea i kahi ambulance. I kēia manawa ua hoʻoholo wau e lawe i kēia mau pil. E nānā wau a hele i ke kauka no ka kūkākūkā ʻana.

Pēlā i haʻi ʻia nā contraindications.

Lawe au i atorvastatin 5 lā. Laumapa. He walaʻau leo ​​ma ke poʻo. Aia nā wāwae wāwae pō ma kēia pō. Ka lāʻau lapaʻau. akā ʻoliala 9, 3. Ua kuhikuhi ke kauka. Ke waiho ʻole ʻia mai nā meaʻai nā huahana holoholona a pau. Holo wale ka umauma moa kao. E ʻike wau i ka hopena i hoʻokahi mahina.

Ua paʻa wau e lawe i Atorvastatin i hoʻokahi lā wale nō, a ua hoʻomaka wau e hōʻole. ʻAʻole pono kēia lāʻau lapaʻau iaʻu, e like me ka maʻi osteoarthritis a me ka maʻi degenerative disc me nā ʻehaʻī o hope. Ua hala wau i kekahi mau mea pena pena mau manawa. Ke makaʻu wale nei au e pili ʻole ʻia kēia ʻano maʻi me kaʻu mau lāʻau. I ka lā aʻe, ua paʻa paʻa ʻia koʻu pepeiao ʻākau, ua ʻeha iaʻu ma kahi ʻeha. Ua emi ʻole kēlā mau palupalu a iaʻu i ke ao a hoʻi hou i ka moena, hiamoe wau i ka lā a pau.

Ua kauoha ʻia au i 40 mg o Atorvastatin no ka ʻeha ʻeha. Aia wau

Ua kauoha ʻia au i 40 mg o Atorvastatin no ka ʻeha ʻeha. Ua hala wau ma 9 mau mahina. Ua hoʻohaʻahaʻa ia i kaʻu kolesterol, akā ua nui nā hopena maikaʻi ʻole e makemake ai! ʻIke koke wau i kahi pilikia hoʻomanaʻo, hoʻomaka wau e poina i nā mea āpau, kekahi ʻano kahapaha i loko o koʻu poʻo i kūkulu ʻia. Hoʻomaka pū kekahi nā hōʻeha o ka naʻau. A ua hoʻomaka kaʻu wahine e mālama pono i ka huki a kaʻeha, huhū wau i waho o ka uliuli, piha ʻole no ke kumu ʻole.

Nā Hōʻike Pono

ʻAʻole hoʻi au i kōkua a loaʻa i ka hopena ʻaoʻao. Kūpili i kahi papaʻai paʻa. ʻAe mai ka sausage, nā hua, ke kō a me ka pata. Pēlā pū ka palaoa. Ma hope o 2 mau mahina ʻaʻole au i emi i ke kaumaha, akā ua ulu maoli ka cholesterol

He 7.1, mahope o ka lawe ana ia 7.2

Maikaʻi ka lāʻau, ʻoiai i nā pule mua ʻelua he hala iki, a laila ua hala ʻia. Pōmaikaʻi me ka lāʻau lapaʻau, huli koke ka kolamu i ka maʻamau 10.3-5.1. ʻO ka mea ma mua nei, ua haʻi kekahi hoahele (atherosclerosis) ua ʻōlelo ʻo ia i ka rosuvastatin-sz, he statin nō naʻe, akā he ʻano mea like loa o kēia lā he mau wahi liʻiliʻi paha. ʻAʻole au i ʻike inā pono e hoʻololi i ka lāʻau, no ka mea, ʻaʻole hopohopo hou.

He lāʻau lapaʻau maikaʻi ʻo Atorvastatin i hoʻohana ʻia no ka wā lōʻihi. ʻO ka mea wale nō i kauoha ʻia i kēia manawa ʻo ka hanauna hou o nā statins. Me he mea lā ke manaʻoʻiʻo ia he liʻiliʻi iki ka hopena. Hoʻohālikelike ʻo Atorvastatin i ke kumukūʻai ma rosuvastatin-sz, akā ʻoi aku ka mana o kahi hou.

ʻAʻole au i ʻike i ka ʻokoʻa ma waena o ka atorvastatin a me rosuvastatin. Lawe wau i ka atorvastatin no 4 mau mahina, ua hoʻi ka kolala i ka maʻamau, a laila ua ʻōlelo ke kauka i ka rosuvastatin-sz - ʻĀina hoʻi ka kolamu, maikaʻi wau. Manaʻo wau eʻoi aʻe ka maikaʻi o ka lāʻau hou.

Lawe au i nā atorvastatin 2 mau papa, hoʻohaʻahaʻa maikaʻi ia i ka cholesterol, ua hoʻomakaʻuʻū ʻē aʻe iaʻu e ka maʻi maʻi, inā ʻaʻole maikaʻi nā mea a pau. A laila, ma ke kauoha o ke kauka, ua hoʻololi ʻo ia i rosuvastatin-sz, ʻo kēia ka huaʻōlelo o nā statins. No nā hopena ʻaoʻao, pono pū kekahi.

Nā pono: Hiki ke hoʻohana ʻia ka lāʻau lapaʻau no ka manawa lōʻihi, i kahi liʻiliʻi haʻahaʻa.

Loaʻa i nā pono: Pono e hoʻohana ʻia ka lāʻau lapaʻau me kahi analgesic, mai hope o ka lawe ʻana i ke poʻo hōʻeha.

Ua hoʻohana nui wau i ka lāʻau lapaʻau no ka manawa lōʻihi, ma ka liʻiliʻi haʻahaʻa, ʻoiai ua emi iki nā kiko o ka cholesterol. Pono ʻoe e lawe me kahi analgesic, no ka mea ma hope o ka lawe ʻana, loaʻa kahi hōʻeha. Kauka ke kauka e lawe i ka lāʻau lapaʻau i ka pō. No laila, hele ʻoe e hele ai, lawe wau ia me kahi analgesic.

Atorvastatin - kahi lāʻau e hoʻohaʻahaʻa i ka cholesterol

I ka pūnāwai, ʻoiai ma ka waiho ʻana me ka maʻi maʻi o ka maʻi hanu, ua hele mai au ma lalo o ka nānā ʻana i ka maʻi olakino āpau, a no laila, e like me nā poʻe maʻi āpau o koʻu makahiki hānau, pono nō ia e hoʻomākaʻi i ka ʻĀina piha. Hāʻawi ka mea lapaʻau i ka hopena ma nā hopena a pau. I kaʻu hōʻike koko biochemical i hōʻike ʻia i nā helu o ka cholesterol, triglycerides a me kekahi mea ʻē aʻe ma laila. Ua loaʻa koʻu māmā i ka infococote myocardial, ua loaʻa iaʻu kahi maʻi hypertension, no laila, ke ʻōlelo nei ke kauka, aia wau i ka pūʻulu kuleana no ka hoʻomohala ʻana o ka IHD a me ka hōʻeha ʻana ma ka naʻau, ua kuhikuhi mai iaʻu i nā papa Atorvastatin 20 mg 1/2 tab. i ka maka? i. Eia kekahi, ua haʻi ikaika ke kauka iaʻu e hahai i kahi meaʻai. Ma hope o hoʻokahi mahina mai ka hoʻomaka ʻana o ka mālama ʻana, ua hana hou wau i kahi hōʻoia koko. ʻAʻole i leʻaleʻa ke kauka i ka hopena a hoʻonui i ka momona i 1 papa. Ua mālama ʻia au no kekahi mahina ʻē aʻe. ʻO ka mea hope loa, ua hāʻawi i ka hopena i ka hopena, ua emi nui ka cholesterol. Hoʻomau hou aku wau e inu i Atorvastatin.

Heluhelu wau i nā ʻōkuhi - e koʻu Akua, i ka nui o ka hopena i hiki i kēia lāʻau lapaʻau ke loaʻa! A ʻōlelo mai ke kauka wau e lawe au i kēia manawa no ka manawa lōʻihi, no laila hiki ʻole iaʻu ke hōʻalo i nā hopena. Akā i kēia manawa ʻaʻole wau e nānā i kekahi mea.

ʻO ka lāʻau maikaʻi. Akā e aʻo ʻia nā poʻe cardiologists e loiloi ma ke kumu o ka pōmaikaʻi. Ka hopena maikaʻiʻole ma ka ate. E poina e lawe i nā statins i nā koloka maikaʻi a maikaʻi hoʻi mai ka kino.

ʻAʻole maikaʻi loa ka hoʻopōʻino i ka lāʻau maʻa. Ma mua o ka hoʻomaka ʻana e lawe i nā statins (nā lāʻau e hoʻokaʻawale i ke kolamu o ke koko) pono ʻoe e hoʻololi i kou ola, e noʻonoʻo hou i kāu papaʻai, a inā wale nō, ma hope o ka hapalua makahiki, ʻaʻole hoʻi ka cholesterol i ka maʻamau, a laila hoʻomaka ka lawe ʻana i Atorvastatin.

Ua hoʻopaʻa inoa kāna kāne i ka hypercholesterolemia a me ka hyperlipidemia ma kahi hōʻike koko biochemical no kekahi mau makahiki. ʻAʻole hāʻawi ka mea ʻai i ka hopena kūikawā, ʻoiai i ka wā wikiwiki, ke hōʻole mākou i ka ʻai, ʻaʻole i emi ka cholesterol i nā kumu maʻamau. Kauka ke kauka iā ia i ka lāʻau Atorvastatin 10 mg hoʻokahi i ka lā. Ma hope o ka hoʻomaka ʻana o ka inu, ʻelua mau pule ma hope o ka loaʻa ʻana o ka loiloi, hoʻokahi mahina ma hope iho ua komo ke kolamu i ka palena o ka maʻamau.

He paʻakikī loa ka hana o ka lāʻau, hiki ke kāpae mua i ka synthesis o kolesterol, a me ka lua o ka hoʻonui ʻana i ke kiʻekiʻe o nā receptors i ke kōleo i ke kolamu, e alakaʻi ana i kona hana wikiwiki loa i loko o ka huela.

He haʻahaʻa loa ka lāʻau no kahi papa ma mua o hoʻokahi mahina - e pili ana i ka 350 rubles. Hiki iā ʻoe ke inu i kahi papa pākaukau e pili ana i ka pāʻina, no laila he mea maikaʻi loa ia, no ka mea e poina ʻoe e inu i nā lāʻau he nui i ka ʻōpū ʻole a kali i ka hapalua lā a hiki iā ʻoe ke lawe. Ma hope o ka hoʻomaka ʻana o ka mālama ʻana, ua loaʻa nā hopena o ke kāne. Ua loli kekahi biochemistry, ua lele i nāʻu hepatic liʻiliʻi, ua palupalu ia, he ʻeha. Ma hope iho ua hala nā mea āpau, ʻoiai ʻaʻole i emi ka huaʻai o ke ake a hiki i ka hoʻokuʻu ʻia ʻana o ka lāʻau. Ua inu ʻo ia ma Atorvastatin no ʻelua malama.

Ma keʻano ākea, maikaʻi maikaʻi ka lāʻau lapaʻau, ʻaʻole ia e kōkua i ka maikaʻi, ʻoiai ʻaʻole hiki ke hana me nā hopena ʻole.

He pane kūpono

Ke heluhelu nei wau i nā loiloi a ke piʻi wale nei au, ua ʻike au i kekahi ʻano haʻalulu.ʻU ke inu nei au i kēia lāʻau lapaʻau no 1.5 mau mahina ʻaʻole oʻu loaʻa ʻana i nā pilikia olakino. Me he haʻahaʻa haʻahaʻa koko a me kahi puʻuwai wikiwiki, ʻaʻohe mea nui. e lawe ʻia kahi hōʻike koko a ʻike iā cholystyrin e ʻike ai, ʻo 6.2..ʻOhe ʻaʻohe pilikia pilikia o ke olakino

Hoʻopili maikaʻi nā lāʻau ʻelua i ka hana - hoʻohaʻahaʻa i ka cholesterol. ʻO wau iho wau i ka atorvastatin-sz, lawe nei au iā rosuvastatin-sz. I ka laulā, ua loaʻa iaʻu ka 10 "ʻike" i ka lawe ʻana i nā statins, i ka makahiki 2009 ua kau lākou i ka hypercholesterolemia + e hoʻopiʻi e pili ana i ka maʻi maʻi. Lawe ʻo Atorvastatin-sz i mau makahiki 7, mai ka lua o ka malama o ka lawe ʻana i ka 5.8-6.2 ʻaoʻao ʻaoʻao ʻaʻole i ʻike ʻia. A laila, i ka makahiki 2016, ua paipai lākou iaʻu rosuvastatin-sz, ka lāʻau lapaʻau statin hou aku. Ua hele loa au, ʻaʻole au i manaʻo i kekahi mau loli i ka maʻamau, i noho maʻamau koʻu kolamu. No laila ua manaʻo wau - ke ʻano a me ka waihoʻoluʻu .. ʻokoʻa hou aʻe paha, ʻaʻole i ʻike ʻia kekahi mau kaʻina.

Kūʻē wau i ka lāʻau lapaʻau. Ua hala koʻu makuakāne mau makahiki 7, hoʻomanaʻo ʻo ia i ka kolamu hoʻokahi wale nō i kēlā me kēia mahina 6, i ka wā i hana ai ʻo ia i kahi ʻōlelo lipid. I kēia manawa ke lawe nei ʻo ia i ka rosuvastatin-sz, e like me ka mea hou mai ka lāʻau hou, a no laila makemake wau i kēia mea. ʻAe, maʻalahi mau kēia e lawe no ka mea 1 papa i ka lā

ʻO ka lāʻau maikaʻi. Lawe ʻo ia iā ia i kahi lōʻihi a hiki pū hoʻi kāna kāne. Ua hana ʻo Cholesterol ma nā makahiki he nui, he aloha nui ka mea pono ke lawe i ka statins i kou ola a pau. i hoʻokahi mahina i hala aku nei, ua ʻōlelo ke kauka e hoʻohuli kāna kāne i kahi piʻi rosuvastatin-sz hou o kēia lā. ʻO ke kolala, ʻoi aku ka maʻamau o ke kolamu. I kēia manawa wau e noʻonoʻo nei, hiki iaʻu ke hoʻololi i ka lāʻau lapaʻau a noho paha i ka atorvastatin ?.

Hoʻohana ʻia nā statins o ka 1 a me ka 2 mau makahiki. ʻIke wale wau i nā hanauna 3 i ka pākahu atorvastatin - i koʻu lawe ʻana, he lāʻau lapaʻau maikaʻi. Kekahi makahiki ua hoʻokō kūlike ʻo ia iā rosuvastatin-sz 4 mau hanauna. Kāleka 4.5, ʻaʻohe hopena o ka hopena.

Pono maikaʻi ka lāʻau lapaʻau, lawe ia e like me 5 mau makahiki. ʻAʻole i hele ke kolala a ʻoi aku i kahi maʻamau. 2 mau makahiki i hala aku nei, ua hoʻololi lākou (nā mea a pau e like me ka mea i kau ʻia e ke kauka) me rosuvastatin-sz, manaʻo hou aʻe, he like ka hopena - ʻaʻole ʻike wau i ke ʻano, akā hana.

Inu ka makuakāne o Atorvastatin e koʻu makuakāne, ua hāʻawi ʻia e inu iā lākou no ke ola. Ua emi ka maikaʻi o Kolololi, ʻo ka pilikia me ka triglycerides. Ua kuhikuhi pū ʻia ʻo Dibicor, a ua hoʻomaka ka triglycerides i ka emi ʻana o ke akeʻa i ka pāʻani ʻana i nā poli, ʻike ʻia ka dibicor e pale iā ia.

lawe i ka atorvastatin no ke kolamu nui, ua kōkua ʻo ia, akā naʻe, make ka maʻi iā ia. Ua noi ʻo ia i ke kauka e koho i kekahi mea ʻē aʻe, ua ʻōlelo ʻo ia e hoʻāʻo iā rosuvastatin-sz - ua like kēia me kahi hanauna hou. Lawe wau i hoʻokahi mahina, ua ʻōkau nā mea a pau.

Ke lawe nei au i ka atorvastatin-sz no ka lua o ka makahiki, ua aneane ka maʻamau o cholesterol, a ke manaʻo nei nō hoʻi ua kōkua iaʻu e nalo i kekahi mau kg. Ua kōkua nui ʻo ia iaʻu, i ka papa ʻaina ʻaʻole wau e lōʻihi.

Ua kuhikuhi ʻia ʻo Atorvastatin ss noʻu e hoʻohaʻahaʻa i ka cholesterol. He pilikia mākou i ka ʻohana a ʻike wau no ia mea. Hoʻopau pinepine wau iā ia i nā papa, ʻaʻole kū ka cholesterol, ʻaʻole i loaʻa iaʻu kekahi pōʻino i koʻu olakino.

Ua kākau nā mea a pau e kōkua ka ʻai me ka kolesterol, akā ʻaʻole naʻe kēia - ua hōʻike paʻa ʻia ka kolepa nui i loko o ke kino ponoʻī. ʻO Atorvastatin kahi penikala maikaʻi a kōkua i ka mālama ʻana, akā ʻo kēia mua ka hanauna o nā statins, i kēia manawa ua nui nā mea hou. Lawe au i ka rosuvastatin-sz - he maikaʻi ka hopena, akā liʻiliʻi ka hopena.

ʻAʻole wau i maopopo i koʻu pilikia ʻana i ka cholesterol a hiki i ka manawa, loaʻa kekahi kauka i kēia. Ua inu wau i ka papa o Atorvastatin sz a hahai i kahi papaʻai. No ka mea ua emi iho ʻo Cholesterol, no laila, aʻo wau.

I ka manawa e ʻike ʻia ai ka cholesterol kiʻekiʻe, ua kau ʻia iaʻu ma Atorvastatin cz. Ua ʻeha hou wau i ka hele ʻana i ka ʻai. Akā ua huli hope i nalo i ke kaupaona. A maikaʻi ka lāʻau lapaʻau, ʻoluʻolu me ia.

Inu inu ʻo Atorvastatin sz e koʻu makuahine. Loaʻa iā ia nā pilikia me ka cholesterol a me ka helu 2 hypertension. Hele hou mai ʻo Cholesterol ma ke ʻano maʻamau, inu mākou i nā papa. Nui nā hopena keu ma nā ʻōkuhi, akā ʻaʻohe mea i ʻike ʻia i loko o koʻu makuahine.

• Kōkua i ka hekili koko

Ua loaʻa iaʻu kahi mau uha, lele ka piʻi koko a hoʻomaka i ka helu he palupalu. a hele au i ke kauka, hele i nā hoʻokolohua a pau, hana i kahi ultrasound o nā kīʻaha o ka lolo a ua kau ʻia ke kauka iaʻu i nā papa ʻula otorvostatin. Hoʻomaka wau e inu i kahi papa o 20 milligrams hoʻokahi manawa i ka lā hoʻokahi, hoʻomaka ka hoʻomaikaʻi ʻana o koʻu ʻano, lele kaʻe koko, a pēlā aku. ʻO kēlā me kēia mahina aʻu e hana nei i nā hoʻokolohua e nānā i koʻu kolamu o koʻu koko a ʻoiai inu wau i kēia mau papa he maʻamau nā mea āpau. Ua hoʻololi hou au i kēia mau peni me nā ʻoihana hou aku, akā, ua hoʻohuli wau, ua hoʻi hou wau i ka atorvostatin a maikaʻi wau i ka maikaʻi.

ʻO nā peni maikaʻi loaʻaʻole i hoʻohaʻahaʻa i ka cholesterol koko

Ua kōkua nui ʻo Atorvastatin i ka nui o ke kolamu mai 6, 4 i ka hōʻemi i ka 3, 8, ke inu nei wau ma mua o ka makahiki hoʻokahi, me ka haʻahaʻa o ka dosage mai ka 40 mg a 10. ʻO kēlā me kēia mahina, hāʻawi wau i ke koko no ka hoʻokolokolo. I kēia manawa hiki ke lawe i ka wai mālama mālama, ʻaʻole ia i kēlā me kēia lā, e like me ka wā ma mua, akā no ka laʻana 2 mau manawa i ka hebedoma. No laila pehea ka inu ʻana ma hope o kahi kūmake i loaʻa ai kēia lāʻau lapaʻau no ke ola!

Inu koʻu māmā, ua hoʻokuʻu ʻia ʻo ia no ke ola. Loaʻa iā ia he 9 cholesterol, a he nui kāu. I ka wā i hoʻomaka ai iaʻu e hoʻohana i ka Atorvastatin, a hoʻokahi mahina ma hope, ua kihi: ua hāʻule kēlā kolamu ma ka maʻamau. Akā ʻo ia, ʻo kahi mea e like ka mea, ke inu mau nei ia, no ka mea ʻole o ke kino ponoʻī ke hoʻoponopono i kona pae ma muli o ka palaki metabolic. ʻAʻole i ʻike ʻia nā hopena ʻaoʻao.

Ua hoʻihoʻi ʻo Atorvastatin i kaʻu kolamu i ke ʻano maʻamau. ʻOiai ua hānai ʻia ia ma mua a ʻaʻole i kōkua ka paʻakai kime a me ka momona momona, akā ua kōkua kēia lāʻau lapaʻau. Ke hahai nei au i nā ʻiʻo, me ka hiki i nā stins ke luku iā lākou a hoʻoōwaliwali i ka nāwaliwali. Ke kuhikuhi aku nei au iā ʻoe e hana i kēia i nā cores a pau i lawe i nā lāʻau i kēia hui.

• Hoʻopono ʻole me nā lāʻau lapaʻau he nui.

Ua kuhikuhi ʻia kēia lāʻau lapaʻau i koʻu kupuna wahine, ʻo ia hoʻi, ma ka ʻokoʻa o ke hypertension, he kolikoli kiʻekiʻe. Akā, ʻoi aku ka maikaʻi o kēia lāʻau lapaʻau me ka nui o nā lāʻau antihypertensive.

Ma ka hoʻomaka mua ʻana, pono e inu ʻia ka lāʻau i hoʻokahi manawa i ka lā, akā koʻikoʻi loa ia e kiaʻi i ka pae o ke kolamu ma ke koko, ʻo ia hoʻi, e hana i nā hōʻike. Ma hope o nā hōʻike hōʻike e hana ana ka lāʻau lapaʻau me ke hōʻike ʻole o ka pathological, hiki ke hoʻonui ʻia ka nui. Pono e nānā pono i ka wā o ke kaʻina hana e hoʻohana ʻole i kekahi lāʻau lapaʻau e hiki ke hoʻonui i ka mea hoʻoikaika i ka kaila koko, hiki iā ia ke alakaʻi i nā hopena maikaʻi ʻole. ʻO ia mau lāʻau me ka antibiotics, nā lāʻau antifungal, ka waikika ʻoototinik.

I ka hopena o ka mahina mua o ka lawe ʻana i kaʻu kolamu, ua hoʻohaʻahaʻa koʻu kupuna wahine a lilo i loko o nā palena maʻamau.

Eia naʻe, pilikia ka pilikia o ke kolamu kiʻekiʻe i kēia lā. Inā ma kahi ʻōpio ʻōpiopio ka pale ʻana o ke kino me ka cholesterol ʻoi loa ka pōʻino, a ma hope o 35 mau makahiki he mea pono ke nānā pono i ke olakino a me nā helu koko āpau. ʻOi aku ka maikaʻi ma ka hoʻomaopopo koke i ka kolala a ʻaʻole i ʻae i ka hoʻonui ʻana ma luna o ka mea i ʻae ʻia. Inā hiki iā ʻoe ke lawe i nā hoʻokolohua i kēlā me kēia makahiki, a ʻoi aku ka nui o ka manawa, a laila hiki iā ʻoe ke maʻalahi me ka nānā ʻana i nā moʻomeheu o ka pae o ka kolamu ma ke koko.

Akā inā he hanana a ʻoi aku ka kolamu ma mua o ka pākaukau, a laila ʻaʻole ʻoe e kāpae i ka mālama ʻana i ka pahu lōʻihi, pono ʻoe e lawe i nā lāʻau kūpono. ʻO ka Atorvastatin kahi lāʻau lapaʻau maikaʻi e hōʻemi ai i ka cholesterol.

He haʻahaʻa ke kumukūʻai, kūʻai ke kumukūʻai ma kahi o 160-180 rubles, kūʻai aku i kēlā me kēia pākaha, hiki ke kumukūʻai ke kumukūʻai i ka palena o kekahi kaulahao lāʻau.

E kūleʻa maikaʻi ʻo Atorvastatin i ka hui pū me ka meaʻai kūpono, kākau ʻia ma nā ʻōlelo aʻoaʻo, ua ʻōlelo hou ke kauka nei i kāna hana ʻana i nā papa Atorvastatin.

He mea nui loa e lawe i nā hoʻokolohua ma mua o ka hoʻomaka ʻana i ka mālama ʻana i mea e ʻike ʻia ai ka nui o ka pae o ke kolamu, e pono ai i ka helu ʻana i ka maʻi o ka lāʻau. ʻO koʻu hihia, he 1 papa 3 mau manawa i ka lā no ka mahina. Hiki i nā Dosisages ke ʻano, a hiki i ka 8 papa, akā hoʻohālikelike ʻia kēia a alakaʻi ʻia e kahi loea.

I hoʻokahi mahina ma hope iho, ua hoʻolālā ʻia kahi hōʻike koko e ʻike ai inā kope ʻia ka lāʻau inā ʻaʻole paha. Ma hope o kēia manawa, hāʻawi hou au i ke koko, e like me ka hōʻike ʻana o nā hopena, ʻo ka hopena a loaʻa ka hopena nui o ka kolesterol, akā e noho wale ana kona pae ma waho o ke ʻano maʻamau, ua hoʻoholo ʻia e inu i Atorvastatin no nā wiki he 2 me ka like pū ma kahi like a me ka manawa like ka inu ʻana i ka wai thistle ʻai no ka pēpē. Kōkua kēia meaʻaiʻai meaʻai e hoʻohaʻahaʻa i ka cholesterol.

Ma hope o 2 mau pule, ua hoʻi hou nā hōʻike, ua ʻoluʻolu wau, akā ʻaʻole kēia he kumu e hoʻomaha ai. ʻAe, ua hoʻopau ʻia ke lāʻau Atorvastatin, akā aia wale nō i ka meaʻai a me ka mālama mau ʻana i ke olakino.

Ua kōkua maoli ʻia ka lāʻau lapaʻau iaʻu, lawe mai wau i ka kolamu i ka maʻamau, ʻoi wale nō wau e mālama i ka ʻai paʻa, inā ʻaʻole hiki ke kūleʻa ke kaulahao: kolamu - Atorvastatin a me nā wīwī, aia kekahi pilikia me ka puʻuwai (heluhelu i nā hopena ʻaoʻao). He hōʻino wale ʻia ka lāʻau lapaʻau, ʻaʻole iʻoi aku ka hewa ma mua o ka hoʻopili, akā nā kāne, pono ʻoe e haʻalele i ka chemistry a hoʻopaʻa iā ia me ka pata, sausage a me nā momona a me nā ʻoliʻoli ʻē aʻe. Ehia ..

Keʻai nui nei me ka kolamu kiʻekiʻe e hoʻokani i ka hana koʻikoʻi. ʻO koʻu kupuna wahine kekahi kolamu piha o 10 mmol / L. Ua ʻōlelo ke kauka e hahai i kekahi kīpī: nā momona holoholona liʻiliʻi (inā he ʻai, a laila moa ka moa momona, a me nā kuʻupaʻa), ʻoi aku ka nui o nā mea kanu, nā hua (ʻo nā huaʻai i makemake ʻole ʻia), e nānā i ka pauku wai inu. Ua kuhikuhi ʻia ʻo Atorvastatin mai nā lāʻau lapaʻau. Ua lawe ka kupuna kāne i ka lāʻau lapaʻau i ka manawa 1 i ka lā. Eono mahina ma hope iho, ua hoʻokō ʻia nā hopena ma hope iho: ua hōʻemi ʻia ke kaumaha ma ka 14 kg (ua kūpono ke ʻai i ka pono kūpono), ua lilo ke kolala. I kēia manawa ua pau ka hoʻoweliweli ʻana o ka atherosclerosis.

Nā kumukūʻai Atorvastatin i loko o nā hale kūʻaiʻai ma Moscow

Hōʻike nā kauka e pili ana i ka atorvastatin

Ua loaʻa kēia lāʻau lapaʻau i ka hopena therapeutic i ka mālamaʻana i nā kūlana o ka hyperlipidemic me ka maʻi ʻeha coronary. Maikaʻi maikaʻi o ke kumukūʻai a me ka hana pono o kēia lāʻau lapaʻau.

Aia nā hopena kūpono o nā ʻaoʻao.

Hiki ke hiki ke noi ma hope o ke kūkā ʻana a me ke kau ʻana i kahi maʻi lapaʻau.

ʻO kahi maikaʻi maikaʻi loa a me nā kumu kūʻai kumu kūʻai no ka mālama ʻana i ka hyperlipidemia me kahi maʻa mua e hana ʻia a me ka regimen papa.

Hōʻike ka lōʻihi o ka lāʻau lapaʻau lōʻihi me ka hoʻohana ʻana i kahi lāʻau lapaʻau e pono ʻole i ke kumukūʻai loa, aia nā hihia i ka hōʻole ʻana o kēia lāʻau lapaʻau ma muli o ke kumukūʻai haʻahaʻa, manaʻo ke kanaka i ka mea kūʻai wale, ʻo ia ka mea e kōkua ʻole ʻia.

ʻO ke kumukūʻai o ka lāʻau lapaʻau, ʻo kona loaʻa i ka poʻe i loko o ko mākou'āina, ka hopena e pili ana i kāna hopena ola nui.

Nui nā hopena o ka lāʻau lapaʻau, i loaʻa i ka hapa nui o nā lāʻau mai ka pūʻulu o nā lipid-hoʻemi haʻahaʻa a i nā statins kūikawā, ka pono o ka mālama ikaika o ka hōʻike koko biochemical.

ʻAkeʻane nā mea a pau a nā poʻe a pau e ʻike ai no ka waiwai "atorvastatin" e pili ana i ka lāʻau kanu "Liprimar" na Pfizer. No laila he nui nā lāʻau lapaʻau e hana i ko lākou atorvastatin, akā. Ma mua o ka holomua. No laila, inā ʻaʻole ʻoe ʻoluʻolu i ka hopena o ka lawe ʻana i ka atorvastatin, aneʻa pinepine kēia ʻōpona i kēia lāʻau lapaʻau, me ka nui o ke kumukūʻai ʻo 100-200 rubles. Aia nā generics o lypimar i hōʻike i ka hoʻohālike therapeutic - ma ka liʻiliʻi loa e pili ana i ko lākou hiki ke hoʻohaʻahaʻa i ka cholesterol koko. ʻO kekahi hiʻohiʻona e atoris. Ma ka lypimar generic haʻahaʻa, loaʻa i kekahi mea waiwai ʻokoʻa i ka manawa i loaʻa i kekahi manawa - ʻoi aku ka nui o nā hopena ʻokoʻa ma mua o ka pono o ka lāʻau mua. ʻO kēia, ʻo ia hoʻi ke ʻōlelo, he uku no ka uku nui o kahi mea i kūʻai ʻole ʻia a ʻikea ʻia ma ke ʻano o nā papa o ke ʻona ʻē aʻe atorvastatin. Atorvastatin, me ka rosuvastatin, ʻelua mau loina paʻa mau i hoʻopaʻa ʻia ma Rusia. ʻOiaʻiʻo, pono ʻoe e hoʻomaopopo i ka ʻokoʻa ma waena o ka atorvastatin mua - Liprimar, a me nā loea. ʻAʻole hiki i nā mea ʻenehana āpau ke haki i kahi lāʻau lapaʻau e ʻaʻole i hoʻomohala i kēia lāʻau lapaʻau. No laila, pono ʻoe e koho wale i kēlā mau lāʻau (me nā statins) i loaʻa nā hopena maikaʻi o nā haʻawina ma ke ʻano therapeutic. ʻO kēia ka manaʻo, ʻo ka atoris ka mea maʻamau i hoʻopaʻa ʻia ma ka atorvastatin. ʻOi aku ka maikaʻi me ka hilinaʻi i ke kauka ma kēia ʻike, ʻo ka hoʻomaopopo ʻana i ka manawa like ʻaʻole like nā kauka a pau.

ʻAʻole hiki i nā kumu ʻoi aku ka uku, a inā ʻaʻole pono kekahi e mākaukau no ka ʻole o ka hopena a i ʻole ke kiʻekiʻe o nā hopena ʻaoʻao. Nui ka helu o nā loina o ka atorvastatin, ʻaʻole naʻe nā mea āpau i kūpono i ka hilinaʻi like e like me ka lālani "Liprimar".

Hōʻike wau i ka hōʻailona, ​​pono e hāʻawi ʻia ma ʻaneʻi, wale nō (!) I ka lāʻau lapaʻau Liprimar a me kāna ʻano ʻano kiʻekiʻe. ʻAʻohe o "atorvastatins" o 100-200 rubles i loaʻa ma aneʻi.

Hoʻomaopopo nā hōʻike maʻi atorvastatin

ʻO ka mea nei i loaʻa koke nei, ua paʻa wau i ka carotid artery (ʻoi kekahi mea kaniā, e huhū ana i koʻu poʻo - ua ʻike ʻia ʻo atherosclerosis o nā moku). E hana mau i ka piʻi nui o ka cholesterol koko. Wahi a ka hoʻokuʻu ʻana o ke kauka, hoʻopau wau iā Atorvastatin (20 mg.) I kēia manawa, ma hope o ka lawe ʻana, ua puka ka ʻeha i loko o koʻu mau mea. ʻAʻole wau i inu i kēia pōpilikia - ʻaʻohe mea paʻakikī. Pono paha e hoʻololi i kekahi lāʻau lapaʻau ʻē aʻe.

ʻAno poʻe maikaʻi! A hāʻawi ʻo "Atorvastatin" i nā hopena like ʻole, ʻaʻole makemake wau e ola. Hoʻomaha ʻia. A i kēia manawa ua kūʻai au iā "Krestor", ʻoi aku ka maikaʻi. ʻAʻole kahi mea e hele ai. ʻOiai no ka hāʻule ʻana o 10 kg i kēlā me kēia makahiki (ʻoiai ʻaʻole ia e hōʻeha i ka nalo 7-8 kg ma mua o ke kaupaona maʻamau), ʻaʻole i hāʻule ka hāʻule o ka cholesterol, ma ke ʻano ua lilo ia 9, ma kahi o 8 i ka makahiki i hala. Kēlā plue i nā hiamoe āpau mai 30 a 45. A ʻo ka pākeke ma ka coronary pololei ma luna o 70%. Ua koho lākou i kahi hana paʻa e waiho ʻia ma laila, akā ʻaʻole hiki ke hana, e hele wale ana nā stents i ke kauwela. Hoʻokahi wale nō nā hihia pōpilikia inā he pili koko. ʻĀnō wau e noho nei ma luna o kahi pala poli. E ka poʻe, e hana i nā kī ultrasound me nā kauka like ʻole! Ua hana wau ma mua o hoʻokahi manawa, akā wale nō ke kauka hope loa i ʻike i kēia pākī nui! Akā ʻaʻole i loko o 5 mau mahina (mai ka manawa o ka ultrasound hope loa) i hana ʻia, ka mea ma mua o 70%.

ʻO kahi lāʻau lapaʻau maʻamau, ʻae wau i ka lawe maikaʻi ʻana, ʻaʻole wau ʻike i nā hopena ʻaoʻao. ʻO nā kumu haʻahaʻa o nā Cholesterol, ʻo ka pilikia wale nō me ka triglycerides i paʻa ma kahi hoʻokahi. Akā ua hoʻoholo lākou i kēia, ua pili lākou iā Dibicor iā Atorvastatin a ʻo ia wale nō, kokoke pau ka triglycerides i ka palena palena o ke kumu.

Ua hoʻokuʻu ʻia koʻu māmā "Atorvastatin sz" ʻeono mahina i hala. Ua inu nō ʻo ia ia i loko o nā papa, ʻoiaʻiʻo ʻaʻole me ka mea ʻai. ʻĀnō loa ʻo ia, ua hoʻoholo ʻo ia e hoʻomaka i ka papaʻai ai. E nānā pinepine i nā cholesterol, i kēia manawa maʻamau.

ʻO wau ke lawe i ka atorvastatin no 10 mau makahiki, ma hope koke o ka hopu ʻana i kahi mahā a myocardial infarction, a ma hope koke iho ua hana ʻia ka hoʻokele bypass coronary. Manaʻo wau he mea kōkua ke lāʻau lapaʻau iaʻu mai ka cholesterol, a no kekahi mau makahiki i kēia manawa, i ka wā e nānā ʻana iaʻu, maʻamau ka cholesterol.

Inā loaʻa ma mua o 9 mau kolamu ma kaʻu mau ho'āʻo koko, ua manaʻo wau e mālama ʻia ka lāʻau a me ka hopena. Akā i loko o ke kīhāpai, ua loaʻa iā ia kahi pūʻulu o nā paila no 100 rubles, ua makaʻu nuiʻo ia! Akā ʻo kaʻoiaʻiʻo inu wau i kēia pakuhi, e like me ka mea i hāʻawi ʻia iaʻu i kēlā me kēia lā no ka pō. Lalo i kahi reanalysis a ʻaʻohe loli i loli, no ka mea, he lua no ka lua, a paʻa ka maikaʻi. No laila he mea kūpono ka lawe ʻana i kēlā mau pila, kahi hilinaʻi ʻole ʻole ʻia. Ma hope o kēia, ʻo kēia chemistry a ʻaʻole i ʻike ʻia ka mea e hiki ai i ke kino me ka hoʻohana lōʻihi. Hōʻole wau i kēia mau pala, e noi aku au e kākau i ka lāʻau lapaʻau ʻoi aku ka maikaʻi, a ʻaʻole i kahi dummy pono ʻole.

Hoʻonohonoho ʻia e lawe i ka atorvastine me ka cholesterol 6.5. Hoʻomaopopo wau i ka 10 mg i kēlā me kēia lā - ʻaʻole wau i ʻike i ka hopena kūikawā, akā nui ka hopena o nā ʻaoʻao. Ke hoʻāʻo nei wau e hoʻololi i kahi ʻai.

Ua lawe wau i ka Atorvastatin no 2 mau makahiki i kahiʻu o 20 mg. He mea maʻamau ka ʻōlelo lipid, akā kahi mea na ka atilo i hoʻomaka.

ʻAʻole au e ʻōlelo he ʻano kupaianaha kēia lāʻau lapaʻau. Ua kuhikuhi ʻia i koʻu makuakāne ma kahi o 60 mg / lā, no ka mea, he kolamu kiʻekiʻe kona kuʻuna i ka ʻohana. Ke hoʻopiʻi - hōʻoluʻolu o ka hoʻohana ʻana (me ka manaʻo o ka intake meaʻai). Cons - ʻaʻole au i ʻike i kekahi mau loli i ke olakino ma ka hopena o ka mālama ʻana. Kālepa me ka ʻoi aku ma mua o 7 mmol / l, a paʻa. ʻEono mahina ma hope mai, ua kāohi ke kolamu o koʻu makuakāne i ka popliteal artery, ka mea i hoʻonāukiuki i ka nekrosis o ka manamana wāwae nui. Ano, i mea e pale aku ai i ka amputation palua i hoʻokahi makahiki, ua hoʻohui ʻia nā kūpuna me nā lāʻau lapaʻau loa. I koʻu manaʻo, he lāʻau lapaʻau maikaʻi ʻole ka atorvastatin, ʻaʻole wau i ʻike i ka mea a nā kauka i kuhikuhi ai no ia.

Ua kauoha ʻo Therapist i kēia lāʻau lapaʻau i kāna kāne, ʻoiai ʻaʻole i hoʻokiʻekiʻe kāna kolamu. Akā ke kūpaʻa nei ke kaomi, a pēlā pū, me nā lāʻau lapaʻau e hoʻohaʻahaʻa i ke kaomi, ua ʻōlelo ke kauka e lawe i ka atorvastatin 50 mg hoʻokahi i ka lā. Eia naʻe, ua wehewehe ʻo ia ma kēia me he mea ma hope o 40 mau makahiki, ua kuhikuhi ʻia nā statins no nā kumu prophylactic. ʻAno maʻamau kāna kāne me ka hoʻohana ʻana o atorvastatin a ʻaʻohe hopena hopena. Aia ke kumukūʻai ma loko o 150 rubles.

Hoʻohana ʻia ʻo Atorvastatin (ma ke kānāwai, e like me nā statins mua) ʻaʻole wale nō no ka cholesterol kiʻekiʻe, akā ua ʻōlelo pū ʻia no ka pale ʻana i nā maʻi naʻau coronary a me ka atherosclerosis, no laila ua kūʻai pinepine wau iā ia i nā makahiki he nui. A i kēia manawa, ua haʻi ʻia e kahi loea (aʻo i ka lāʻau lapaʻau) e like me nā ʻōlelo noiʻi hou, pono ʻia nā statins ma hope o 40 mau makahiki i nā liʻiliʻi liʻiliʻi a i ʻole ka pae o ka pae cholesterol. Akā pono ʻoe e inu mau - ma kēia hihia wale nō e loaʻa ka hopena.

Ua hoʻomaka wau e lawe i Atorvastatin ma hope o koʻu hoʻāʻo ʻana i ka hoʻoponopono ʻana i ka poʻe āpau e hoʻohaʻahaʻa i ka cholesterol. Ua manaʻo nui ko ia no ka ʻai, akā ʻaʻole e pōmaikaʻi - kū ka cholesterol i ka 7.5. Ma hope o ka lawe ʻana i ka papa o Atorvastatin, lilo ka hōʻailona i ka 4,5. Ua hauʻoli wau a paʻa i ka lawe ʻana i ka lāʻau. I laila! Ua hoʻi hou ʻo Cholesterol i kāna pae mua. E hoʻolōʻihi nā hoaaloha me Atorvastatin i kekahi manawa lōʻihi.

Ua kūʻai aku au i ka pili i ka maʻi maʻi āpau a loaʻa iā lākou ke kaha kiʻekiʻe e hoʻomohala i ka maʻi naʻau coronary. Kūkulu ʻia nā meaʻai ʻai kai me ka papa 1 o ka atorvastatin i kēlā me kēia lā. Ua haʻi mai ke kauka iaʻu e komo i hope o nā hebedoma 4 - pono paha ke hoʻoponopono he hoʻoponopono. I loko o hoʻokahi mahina, ua aneane ka kolamu, no laila ʻaʻole lākou e hoʻonui i ka maʻa. I kēia manawa, ua lawe ka mea pili i ka atorvastatin no hoʻokahi makahiki (+ a me ka hāneakino a me ka haʻalelo) - maʻamau ka maʻamau.

Inu koʻu māmā, ua hoʻokuʻu ʻia ʻo ia no ke ola. Ua loaʻa iā 9 cholesterol, a ua nui nā mea. I ka wā i hoʻomaka ai iaʻu e hoʻohana i ka Atorvastatin, a hoʻokahi mahina ma hope, ua kihi: ua hāʻule kēlā kolamu ma ka maʻamau. Akā ʻo ia, ʻo ia mau mea, ke inu mau nei, ʻoiai ke kino ʻole i ke kino ke kūpaʻa i kona pae ma muli o ka hana hoʻokalakupua. ʻAʻole i ʻike ʻia nā hopena ʻaoʻao.

ʻO ka wehewehe pōkole

ʻO Atorvastatin kahi lāʻau lapaʻau hypolipidemic pili i ka pūʻulu o nā statins. Noho ka maʻi naʻau Coronary i kekahi o nā kūlana alakaʻi i ke kūkulu ʻana o nā maʻi cardiovascular. I ke kumu o kēia neʻe pili ana i ka atherosclerosis o nā keʻa coronary. Hiki i ka hopena o nā hōʻeha o ka atherosclerotic o nā kīʻaha koko ke piʻi i loko o ke alo o ka pono o ka hoʻololi ʻole (hoʻoilina, male, ʻano, makua, ʻano ʻōpio) a me nā hoʻololi i ke kau (ka momona, ke keʻokeʻo, ka maʻi diabetes, dyslipidemia) nā kumu kumu kumu. ʻO ka hoʻokūkū o ka pakanalua ka puhoi, ka mea nui i ka hopena o ka pathogenesis o atherosclerosis, hōʻike ʻia e ka hoʻonui ʻana i ka pae o ka nui a me ka "hewa" kolamu (lipoproteins haʻahaʻa haʻahaʻa a LDL) a me ka triglycerides me ka hoʻohaʻahaʻa manawa i ka pae o ka "maikaʻi" kolesterol (kiʻekiʻe density lipoproteins a HDL). I kahi nui o nā noiʻi nui, ua hōʻike maopopo ʻia e pili ana ka pae o ka cholesterol, LDL a me HDL e pili pono ana i ka make me ka nui mai ka ischemia. E kūʻē i ke kua mua o hypercholesterolemia, nui ka hopena o nā hanana cardiovascular (me ka make make) i kekahi mau manawa.Ma ka manawa like, ua hoʻokolohua ʻia me ka loaʻa nui (a hiki i ka 35%) ka emi ʻana o ka neʻe LDL, ua ʻokoʻa ka hopena o ka make ma ka ʻokoʻa. Ua hoʻāʻo ʻia nā ʻepekema ʻo ka hoʻohaʻahaʻa ʻana i ka nui o ka kolamu ma ka 10% e hōʻemi i ka nui o ka make ma ka maʻi coronary e 40%. Pau kēia mau hōʻike maopopo i ka mea nui o ke kolohe lipid-hoʻohaʻahaʻa i ka pale ʻana o nā maʻi cardiovascular. I kēia manawa, ʻo nā statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) ʻo ia ka lālani mua o ka lāʻau ma ka hoʻoponopono ʻana i nā kūlana dyslipidemic a me ka mālama ʻana i ka atherosclerosis. Hoʻemi lākou i ka pae o LDL a me ka triglycerides atherogenic a hoʻonui i ka ʻike o ka plasma o ka HDL. Loaʻa i nā statins kahi kākoʻo hōʻike paʻa e pili ana i nā hualoaʻa o nā hōʻike lāʻau lapaʻau ākea nui. ʻO nā lāʻau lapaʻau o kēia pūʻulu e hōʻemi nui i nā maʻi o ka maʻi atherosclerotic a me nā hoʻopiʻi e pili pū ana me lākou, e hōʻemi i ka nui o ka pae ʻana o ka plet atherosclerotic a me ka hopena maikaʻi i ka pathology non-cardiac

I kēia manawa ʻo Atorvastatin kekahi o nā mea kaulana kaulana a e aʻo ʻia i ka ʻoihana statin. He lāʻau lapaʻau piha piha kēia i hoʻokomo ikaika i ka hana loiloi mai ka hopena o 90s o ka makahiki hope. ʻO ka hopena o ka atorvastatin ma ke kāpae ʻana o nā hoʻopiʻi cardiovascular, hōʻike ʻia i loko o kekahi helu o nā lāʻau lapaʻau, e ʻae iā mākou e hōʻike i kona hoʻohana ʻana ʻaʻole wale i nā mea maʻi e loaʻa ana i ka maʻi puʻukui coronary, akā pū kekahi pū nō hoʻi i ka poʻe i hiki i ke koʻikoʻi o nā hanana cardiovascular e pili ana i ke kua o ka dyslipidemia. ʻO ka haʻawina kaulana loa o ka hana hypolipidemic o atorvastatin - CURVES - i lawe ʻia i ka waena o ka 1990s i United States. Ma kēia noiʻi ʻana, i ka manawa atorvastatin i hoʻohana ʻia ma kahi o 10-40 mg i kēlā me kēia lā, ka hōʻemi ʻana i ka ʻike o ka cholesterol "maikaʻi ʻole" ua loaʻa i ka 38-51%.

Hoʻolaha koke ka hopena hypypololesterolemic o ka lāʻau lapaʻau a hōʻike i ka mea iā ia i loko o 14 mau lā mai ka hoʻomaka ʻana o ka hoʻokele. ʻOiai ka hopena mua o ka atorvastatin, 10 mg, hiki ke hoʻokō i ka hoʻomaikaʻi koʻikoʻi koʻikoʻi ma ka papa o ka maʻi naʻau coronary ma muli o ka emi ʻana o nā pae LDL e 30% a i ʻole. Hiki ke lawe ʻia i ka Atorvastatin ma nā haʻahaʻa haʻahaʻa ma mua o nā statins (simvastatin, lovastatin, pravastatin a me flavastatin) me kahi hopena therapeutic hoʻohālikelike. Me ka hoʻokele papa o nā lāʻau i ka hapa nui o nā mea maʻi me ka maʻi naʻau coronary i ka manawa pōkole loa no ia mau ala pathological (ma kahi o 3 mau mahina), ua hoʻokō ʻia nā manaʻo LDL kikoʻī. Hoʻopili maikaʻiʻo Atorvastatin i ka pae o ka triglycerides atherogenic i ka hoʻohālikelike ʻana me nā lāʻau lapaʻau ʻē aʻe i kēia hui. Hoʻomaʻamaʻa ʻia ka mālama Atorvastatin e pili ana i kahi kīhāpai o kahi meaʻai kūikawā, kahi e hoʻolako ai i ka hōʻemi o ka waiwai o nā momona holoholona i loko o ke kino a hoʻopili ʻia me nā huaora a me nā minela. Hoʻoholo ka ʻā hoʻokahi ma kahi hoʻokahi a hilinaʻi ma ka pae mua o ka cholesterol. ʻO ka inikua mua o kēlā me kēia lā o ka lāʻau he 10 mg, ʻo ka nui ka 80 mg.

Lapaʻau

ʻO ka lāʻau Hypolipidemic mai ka pūʻulu o nā statins. ʻO ka mea hoʻoneʻeneʻa hoʻāla koho o HMG-CoA reductase, he enzyme e hoʻololi i ka 3-hydroxy-3-methylglutarylcoenzyme A i ka mevalonic acid, ʻo ia ka mea no ka sterols. Hoʻokomo ʻia ʻo Triglycerides a me cholesterol i ka peka i ka VLDL, e komo i ka plasma koko a lawe ʻia i nā kōpili peripheral. Hoʻokumu ʻia ka LDL mai VLDL i ka wā o ke kikowaena me nā mea hopu LDL. Hoʻopili ke Atorvastatin i ka plasma o ke kolamu o ka cholesterol a me nā lipoproteins ma o ka pale ʻana i ka hoʻōla ʻana o HMG-CoA, synthesis o ka kolamu ma ka ate, a me ka hoʻonui ʻana i ka nui o nā mea hōʻemi LDL i ka ate ma ka pūlima, e alakaʻi ai i ka hoʻonui a me ka catabolism o LDL.

Hoʻemi i ka hoʻokumu ʻana o LDL, e hoʻoiho i ka hoʻonui nui ʻana a me ka hoʻomau i ka hana o nā ʻāpono LDL. Hoʻemi i ka LDL i nā mea maʻi me ka hypercholesterolemia homozygous, kahi maʻamau ʻaʻole e pane aku i ka maʻi maʻi me nā lipid-hoʻemi haʻahaʻa.

Hoʻemi i ka pane ʻana o ka kolamu o ka kolamu ma ka 30-46%, LDL - e ka 41-61%, ka apolipoprotein B - e ka 34-50% a me ka triglycerides - e ka 14-33%, kumu i ka hoʻonui ʻana o ka ʻai o ka HDL kolamu a me ka apolipoprotein A. ʻO ka d-paʻa i ka hoʻoliʻiliʻi i ka ʻike LDL ma nā mea maʻi me ka maʻi homozygous herpaio hoʻohālikelike i kū i ka lāʻau me nā mea maʻi hypolipidemic.

Lapaʻau lāʻau

He kiʻekiʻe nā Absorption. Me ka_max i loko o ka plasma ua hōʻea ʻia ma hope o nā hola 1-2. ʻO ka ʻai iki e hoʻemi i ka wikiwiki a me ka lōʻihi o ke komo ʻana o ka lāʻau (e 25% a me 9%, pākuʻi), akā me ka emi ʻana o ka kolamu LDL e like like me ka me ka wikiwiki atorvastatin. ʻO ka ʻike o ka atorvastatin i ka wā i ke ahiahi ma lalo iho o ke kakahiaka (ma kahi o 30%). Ua hōʻike ʻia kahi pilina palena ma waena o ke kūkaʻi o ka huina a me ka loaʻa ʻana o ka lāʻau lapaʻau.

Bioavailability - 12%, bioavailability o ka ʻōnaehana o ka hana pale i kūʻē i ka HMG-CoA reductase - 30%. ʻO ka bioavailability systemic liʻiliʻi ma muli o ka metabolism presystemic i ka mucosa gastrointestinal a i ka wā o ka "papa mua" ma o ka ate.

Waile V_{e d} - 381 l. Hoʻohālikelike i nā protein protein - 98%.

Ka hana i ka nui ma ka ate ma lalo o ka hana a ka cytochrome CYP3A4, CYP3A5 a me CYP3A7 me ka hoʻokumu ʻana i nā metabolites ikaika pharmacologically (ortho- a me para-hydroxylated derivatives, nā hua beta-oxidation). In vitro, ortho- a me para-hydroxylated metabolites he hopena pale i ka HMG-CoA reductase, i hoʻohālikelike ʻia i ka atorvastatin. ʻO ka hopena o ka hopena o ka lāʻau e kūʻē i ka HMG-CoA reductase ma kahi o 70% e hoʻoholo ana e ka hana o nā metabolites ka hele.

Hoʻohui ʻia ia i loko o ka bile ma hope o ka hepatic a / a i ʻole metabolism nui aʻe (ʻaʻole ia i loaʻa i ka enterohepatic recirculation). T_1/2 - Nā hola 14. Ua hana ka hana Inhibitory i ka hoʻoliʻi ʻana o ka HMG-CoA no kahi o 20-30 mau hola ma muli o ka neʻe ʻana o nā metabolites ikaika. ʻOi ka liʻiliʻi o 2% o kahi kūpono i loko o ka waiʻai. ʻAʻole ia i excreted i ka wā hemodialysis.

ʻO ka Pharmacokinetics i nā hui hoʻomanawanui kūikawā

Me ka_max i nā wahine i kiʻekiʻe e 20%, AUC - hoʻohaʻahaʻa ʻia e 10%.

Me ka_max i nā mea maʻi me ka waiʻona cirrhosis o ke akeʻa he 16 mau manawa kiʻekiʻe, AUC - 11 mau manawa kiʻekiʻe ma mua o ka maʻamau.

E hoʻokuʻu i ke ʻano

Ua pani ʻia nā papa papa me ke membrane kiʻi o ke keʻokeʻo a ʻokoʻa paha ia he keʻokeʻo, puni, biconvex, ma ka ʻaoʻao ʻāpana - aneane keokeo.

Nā mea hoʻihoʻi: nā calcium hydrogen phosphate dihydrate - 27 mg, sodium carboxymethyl starch - 3 mg, starch potato - 3,5 mg, magnesium stearate - 0.65 mg, microcrystalline cellulose - 45 mg.

ʻO ka hui pūʻana o ka palaka kiʻiʻoniʻoni: ʻo ke kīpē he 3 mg (ʻo ka mea i mākaukau paʻa o ke ʻula ʻulaʻula a i ʻole ka mākaukau vivacoate i mākaukau hiki ke hoʻohana), komo hypromellose (hydroxypropylmethyl cellulose) - 1.0125 mg, hyprolysis (hydroxypropyl cellulose) - 1.0125 mg, talc - 0.6 mg, titanium dioxide - 0.375 mg.

10 kamepiula - nā kīpaha palemona (1) - nā ʻeke pepa.
10 kamepiula - nā ʻili uila (2) - nā ʻeke pepa.
10 kamepiula - nā kīpaha palemona (3) - nā ʻeke pepa.
15 ʻona. - nā kīpaha palemona (1) - nā ʻeke pepa.
15 ʻona. - nā ʻili uila (2) - nā ʻeke pepa.
15 ʻona. - nā kīpaha palemona (3) - nā ʻeke pepa.
30 kiʻi - nā kīpaha palemona (1) - nā ʻeke pepa.
30 kiʻi - nā ʻili uila (2) - nā ʻeke pepa.
30 kiʻi - nā kīpaha palemona (3) - nā ʻeke pepa.

Ma mua o ka hoʻoluhi ʻana i ka lāʻau Atorvastatin, pono ke kaukaʻi e ʻōlelo i kahi meaʻai lipid-hoʻolaʻa maʻamau, pono ʻo ia e hoʻomau pono ai i ka holo ʻana i loko o ka wā holoʻokoʻa o ka hopena.

Lawe ʻia ka lāʻau lapaʻau ma ke ʻano, i kēlā me kēia manawa o ka lā me ka meaʻai a i ʻole ka manawa ʻole o ka manawa ʻaina.

Koho ʻia ka lā ma ka lawe ʻana i nā pae mua o ka cholesterol / LDL, ke kumu o ka maʻi a me ka hopena ʻokoʻa. ʻO ka ma mua mau ka awelika o 10 mg 1 mau lā / lā. Hoʻololi nā ʻōhua mai 10 a 80 mg 1 mau lā / lā.

I ka hoʻomaka ʻana o ka lāʻau lapaʻau a me / a i ka manawa o ka hoʻonui i ka hoʻonaninani o Atorvastatin, pono ia e kiaʻi i nā mea pili i ka lipid plasma i kēlā me kēia mau hebedoma 2-4 a e hoʻoponopono pono i kēia ʻano.

Me ka hypercholesterolemia koʻikoʻi a me ka hyperlipidemia hui ʻia, a me ka ʻano III a me IV hyperlipidemia e like me Fredrickson, i ka nui o nā hihia ua lawa ia e kuhikuhi i kahi lāʻau lapaʻau ma kahi o ka 10 mg 1 manawa / lā. Loaʻa ka hopena therapeutic koʻikoʻi ma hope o 2 mau pule, ʻo ka hopena therapeutic ākea e nānā pinepine ʻia ma hope o 4 hebedoma. Me ka lōʻihi o ka mālama ʻana, hoʻomau kēia hopena.

Me ka hypercholesterolemia famerial homozygous, ua kuhikuhi ʻia ka lāʻau lapaʻau ma loko o kahi pāʻālua o 80 mg (4 papa o 20 mg) 1 mau manawa / lā.

ʻO ka hoʻohana ʻana o ka lāʻau lapaʻau i nā mea maʻi me ka maikaʻi ʻole o ka maʻi a me ka maʻi ʻōpiopio ʻaʻole i hoʻopilikia i ka pae o ka atorvastatin i loko o ke kaila koko a i ʻole ka pae o ka hōʻemi i ka cholesterol / LDL i ka wā i hoʻohana ʻia, no laila, ʻaʻole pono ke koi ʻana o ka lāʻau.

Me ka nele o ka ate, pono e hoʻemi ʻia ka ʻona.

I ka wā e hoʻohana ai i ka lāʻau lapaʻau i nā mea maʻi ma waena o nā ʻōpiopio, ʻaʻohe ʻokoʻa i ka palekana, ka hopena, a me ka hoʻokō ʻana i nā pahuhopu o ka lipid-lowing therapy i hoʻohālikelike ʻia me ka lehulehu.

Hoʻohui

ʻO ka loaʻa ʻana o ka myopathy i ka wā o ka mālama ʻana me nā lāʻau ʻē aʻe o kēia papa e hoʻonui me ka hoʻohana pū ʻana i ka cyclosporine, fibrates, erythromycin, antifungals e pili ana i ka azoles, a me ka acid nikotinic.

Me ka hoʻohana like ʻana o ka lāʻau Atorvastatin a me kahi kōpana i ʻike ʻia i ka magnesium a me ka alumina hydroxide, ua emi ke kahe o ka atorvastatin i loko o ke koko he 35%, akā ua emi ka nui o ka hōʻemi o ka pae o ka cholesterol / LDL.

Me ka hoʻohana like ʻana o ka atorvastatin ʻaʻole i hoʻopilikia i ka pharmacokinetics o antipyrine (phenazone), no laila, e pili pū ana ka launa pū me nā lāʻau ʻē aʻe e like me ka isoenzymes cytochrome like ʻole.

Me ka hoʻohana pū ʻana o colestipol, hoʻoemi ʻia ke kahe ʻana o ka atorvastatin i loko o ke koko e pili ana i 25%. Eia nō naʻe, ʻoi aku ka hopena o ka lipid-hoʻemi ʻana i ka hui o ka atorvastatin a me colestipol i kēlā me kēia pālolo.

Me ka hoʻohana hou ʻana o ka digoxin a me atorvastatin ma ke ʻano o 10 mg C_{ai ʻo ss} ʻAʻole i loli ka plasma digoxin. Eia naʻe, i ka manawa i hoʻohana ʻia ka digoxin i hui pū me ka atorvastatin ma kahi maʻa o 80 mg / lā, hoʻonui ʻia ka ʻike o ka digoxin ma kahi o 20%. ʻO nā maʻi e loaʻa ana i ka digoxin i hui pū me ka lāʻau Atorvastatin e pono e nānā.

Me ka hoʻohana like ʻana o ka atorvastatin a me ka erythromycin (500 mg 4 mau manawa / lā) a i ʻole clarithromycin (500 mg 2 mau manawa / lā), ka mea e kāohi ana i ka cytochrome CYP3A4, ua hoʻonui ʻia ka piʻi ʻana o ka atorvastatin i loko o ke koko koko.

Me ka hana like o ka atorvastatin (10 mg 1 manawa / lā) a me azithromycin (500 mg 1 manawa / lā), ʻaʻole i loli ka ulu ʻana o ka atorvastatin i loko o ke koko koko.

ʻAʻohe hopena koʻikoʻi ʻo Atorvastatin i ka paʻa ʻana o ka terfenadine i loko o ke kaila koko, ka mea e koho ai i ka nui o nā cytochrome CYP3A4, i kēia mea, ʻaʻole hiki i ka atorvastatin ke hopena koʻikoʻi i nā pākuʻi pharmacokinetic o nā substrat CYP3A4 ʻē aʻe.

Me ka hana like o ka atorvastatin a me ka likaceptive no ka hoʻopale waha e loaʻa ana i ka norethindrone a me ka ethinyl estradiol, he ulu nui loa i ka AUC o norethindrone a me ka ethinyl estradiol i nānā ma kahi o 30% a 20%, kēlā. Pono e noʻonoʻo ʻia kēia hopena ke koho ʻana i kahi contraceptive ā waha no ka wahine e loaʻa ana i ka Atorvastatin.

ʻO ka hoʻohana pū ʻana me nā lāʻau lapaʻau e hōʻemi i ka neʻe ʻana o nā testosterone steroid endogenous (me ka cimetidine, ketoconazole, spironolactone) e hoʻonui i ka hōʻemi o ka hoʻēmi ʻana i nā testosterone stogenous (pono e hana ʻia ka akahele).

Ke aʻo nei i ka hoʻopili ʻana o ka atorvastatin me warfarin a me cimetidine, ʻaʻohe i ʻike nui ʻia o nā maʻi lapaʻau.

Me ka hana like o ka atorvastatin 80 mg a me ka amlodipine 10 mg, ʻaʻole i loli ka pharmacokinetics o atorvastatin ma ke kīʻaha o ka waiwai.

ʻAʻole i ʻike ʻia i nā hopena pōʻino koʻikoʻi o ka atorvastatin a me nā mea antihypertensive.

ʻO ka hoʻohana kūpono ʻana o ka atorvastatin me nā inhibitor protease i kapa ʻia ʻo CYP3A4 inhibitors ua hele pū ʻia me ka hoʻonui o ka hiki ʻana o ka plasma o atorvastatin.

ʻAʻole maopopo ka ʻike lawaleʻa ʻana.

Nā hopena hopena

Mai ka pūnaehana pelupelu: ʻoi aku ma mua o 2% - insomnia, dizziness, emi ma lalo o 2% - hōʻeha o ka poʻo, ka hopena o ka asiniaia, malaise, ka hiamoe, nā poʻomanaʻo, nā paresthesias, neuropathy peripheral, amnesia, luhi ka manaʻo, ataxia, ka palupena o ka palupalu, hyperkinesis, migraine, ʻeha Hypesthesia, nalowale ʻike.

Mai nā naʻau sensory: ʻoi aku ma mua o 2% - amblyopia, tinnitus, conjunctiva maloʻo, hoʻomaha noho, ʻūhū ʻana i ka retina, kamaʻala, glaucoma, parosmia, nalowale o ka ʻono, ka hoʻoweliweli o ka ʻono.

Mai ka pūnaehana cardiovascular: ʻoi aku ma mua o 2% - ʻehaʻeha ma mua o 2% - palpitations, vasodilation hōʻailona, ​​orthostatic hypotension, hoʻonui i ke koko, phlebitis, arrhythmia, angina pectoris.

Mai ka pūnaehana hemopoietic: ma mua o 2% - anemia, lymphadenopathy, thrombocytopenia.

Mai ka papa hana hanu: mau pinepine pinepine 2% - bronchitis, rhinitis, emi pinepine pinepine 2% - pneumonia, dyspnea, exacerbation o ka palaka bronchial, nosebleeds.

Mai ka pūnaehana hana ʻana: ʻoi aku ka pinepine o 2% - hoʻokolohua, emi iho ma lalo o 2% - heartburn, constipation or diarrhea, flatulence, gastralgia, ʻeha ʻeha, hōʻemi a hoʻonui ʻia paha i ka makemake, waha maloʻo, belching, dysphagia, luaʻi, stomatitis, esophagitis, glossitis, erosaʻi a me nā ulcerative lesi o ka wahaosa waha, gastroenteritis, hepatitis, colic biliary, cheilitis, duodenal ulcer, pancreatitis, cholestatic jaundice, hanaʻō luhi functioning, rectalugo, melena, kaomi huela, tenesmus.

Mai ka pūnaehana musculoskeletal: ʻoi aku ma mua o 2% - nā mākala, emi pinepine i ka 2% - nā ʻūhā wāwae, bursitis, tendosynovitis, myositis, myopathy, arthralgia, myalgia, rhabdomyolysis, torticollis, hypertonicity o nā ʻōpū, nā hui pū kekahi.

Mai ka urinary system: pinepine pinepine 2% - peripheral edema, emi mai ka 2% - dysuria (me ka pollakiuria, nocturia, urinary incontinence a urinary retence, pono urination, nephritis, hematuria, nephrourolithiasis.

Mai ka wāʻeha a me nā kelima mammary: ʻoi aku ma mua o 2% - nā maʻi urogenital, emi mai ka 2% - hoʻoheheʻe ʻia, metrorrhagia, epididymitis, hoʻemi i ka libido, ka mākaʻikaʻi, ʻeuʻeu lohi, gynecomastia, mastodynia.

Ma ka ʻāpana o ka ʻili a me nā kiko o ka subcutaneous: ʻoi aku ma mua o 2% - alopecia, xeroderma, hoʻonui nui loa, swezema, seborrhea, ecchymosis, petechiae.

He hopena alerine: emi iho ma lalo o 2% - ʻehaʻeha, ʻeha, hoʻokaʻaʻike dermatitis "i ʻole - urticaria, angioedema, facema edema, photosensitivity, anaphylaxis, erythema multiforme exudative (komo i ke ʻano o Stevens-Johnson syndrome), nā lākī ʻāmaʻomaʻo epidermal (syndrome) Lyella).

Ma ka ʻāpana o nā hōʻailona kuhikuhi: ʻoi aku ma mua o 2% - hyperglycemia, hypoglycemia, hoʻonui serum CPK, albuminuria.

ʻOi aku: haʻahaʻa ma mua o 2% - kahi mahuahua o ke koʻikoʻi o ke kino, hoʻonui i ka gout.

• me ka hui ʻana me ka mea ʻai e hōʻemi ai i ka kolamu ka nui o ka kolamu, kolamu / LDL cholesterol, apolipoprotein B a me nā triglycerides a hoʻonui i ka kolamu HDL i nā mea maʻi me ka hypercholesterolemia haʻahaʻa, heterozygous familial a non-familial hypercholesterolemia a me nā hui pū (hoʻohui) ʻano II hyperlipidemia b)
• i ka hui pū ʻana me kahi meaʻai no ka mālama ʻana i nā maʻi me ka serly triglycerides kiʻekiʻe (Fredrickson type IV) a me nā mea maʻi me dysbetalipoproteinemia (ʻo Fredrickson ʻano III), ka mea e hāʻawi ʻole ai i ka mālamaʻai i ka hopena kūpono.
• hōʻemi i ka hoʻoliʻiliʻi ʻana o ka kolamu a me ka cholesterol / LDL i nā mea maʻi me ka hypercholesterolemia homozygous e pili ana i ka mālama ʻana i ka mālama ʻana i ka meaʻai a me nā lāʻau lapaʻau ʻole ʻē aʻe.

Nā Hoʻohui

• maʻi maʻi ʻōlohelohe a i ʻole ka hoʻonui ʻana i ka hana o nā pepi o nā pulu enema o kahi ʻike ʻole (ʻoi aku ma mua o 3 mau manawa ke hoʻohālikelike ʻia me VGN)
• huni kaʻiole (hōʻeha e like me ke ʻano o nā keiki-Pugh A a me B),
• hapai
• lactation
• a hiki i 18 makahiki (ʻaʻole i hoʻokumu ʻia ka pono a me ka palekana),
• hypersensitivity i nā ʻāpana o ka lāʻau.

Me ka makaʻala, pono e hoʻokaʻawale ʻia ka lāʻau lapaʻau no ka hōʻino ʻana i ka waiʻona, ka mōʻaukala o ka maʻi ʻeha, ka hōʻemi ʻana o ka electrolyte koʻikoʻi, ka hopena endocrine a me ka metabolic, ka maʻi arterial, ʻeha aʻeha koʻikoʻi (sepsis), epilepsy ka pale ʻole, ka nui o ka hōʻemi hōkele, nā hōʻeha, a me nā maʻi ʻeha ʻoihana.

ʻŌpū a me ka lactation

Hoʻokomo ʻia ʻo Atorvastatin i ka wā hāpai a me ka lactation (umauma maʻi).

ʻAʻole i ʻike ʻia inā excreted i ka atorvastatin i loko o ka waiū umauma. Hāʻawi i ka hiki ke hanana ʻino loa i nā pēpē, inā pono, hoʻohana i ka lāʻau lapaʻau i ka wā lactation e hoʻoholo i ka hoʻopau ʻana o ka ʻōpū.

Pono nā wahine o nā makahiki hānau hānau i nā ala kūpono o ka contraception i ka wā mālama. Hiki ke kuhikuhi ʻia ʻo Atorvastatin i nā wahine o ka hānau ʻana inā he haʻahaʻa loa paha ka hiki ʻana o ka hapai, a haʻi ʻia ka mea maʻi e pili ana i ka hiki ʻana mai i ka pūpū i ka wā o ka mālama ʻana.

Hoʻohana no ka hana lawelawe lēwa

Pono e mālama ʻia i ka poʻe maʻi me ka mōʻaukala o ka maʻi ʻōʻai.

Ua hoʻohana ʻia ka hoʻohana ʻana i ka lāʻau maʻi i nā mea maʻi me ka maʻi o ka puʻuwai a i ʻole ka hoʻonui ʻana i ka hana o nā enzyme o nā aʻa mai ʻike ʻole (ʻoi aku ka 3 mau manawa i hoʻohālikelike ʻia me VGN) a me ka pohō o ka puʻuwai (hōʻeha e like me ka helu ʻana o ka Pae-Child a P).

Nā ʻōlelo kikoʻī

Ma mua o ka hoʻomaka ʻana i ka maʻi me ka Atorvastatin, pono e kuhikuhi ʻia ka mea maʻi i kahi meaʻai hypocholesterol maʻamau, pono ia e hahai i ka manawa hana holoʻokoʻa. ʻO ka hoʻohana ʻana o ka inhibitors o ka HMG-CoA reductase e hōʻemi i ka neʻe ʻana o nā lipids i ke koko hiki ke alakaʻi i kahi hoʻololi i nā ʻōhua biochemical e hōʻike ana i ka hana ate. Pono ka nānāʻana o ka naʻau ma mua o ka hoʻomaka ʻana o ka hōʻola, 6 mau hebedoma, 12 mau pule ma hope o ka hoʻomaka ʻana o ka hoʻohana ʻana i ka lāʻau Atorvastatin a ma hope o ka hoʻonui ʻana o kēlā me kēia maʻi, a mālama pū ʻia hoʻi me kēlā me kēia mau mahina. I ka hoʻonui ʻia o ka hana o nā enzyme hepatic i loko o ka serum koko e hiki ke mālama ʻia i ka wā o ka therapy me Atorvastatin. ʻO ka poʻe maʻi i loaʻa ka piʻi o ka hana enzyme e nānā pono a hiki i nā hōʻailona ke hoʻi mai i nā waiwai maʻamau. Ma ka hanana ʻoi aku ka nui o nā mana ALT a i ʻole ACT ma mua o 3 mau manawa i ʻoi aku i ka VGN, ʻoi ʻia ka hoʻēmi ʻana ma ka hopena o Atorvastatin a i ʻole ka hana mālama.

Pono e hoʻohana ʻia ʻo Atorvastatin me ka makaʻala i nā mea maʻi e hōʻino maikaʻi ʻole i ka wai ʻona a me / a i ʻole ke maʻi maʻi. ʻO ka maʻi maʻi ʻola a i ʻole hoʻi e hoʻonui i ka hana o nā aminotransferases o kahi kumu i ʻike ʻole ʻia e lawelawe ana i nā contraindications i ke koho ʻana iā Atorvastatin.

Hiki i ke mālama Atorvastatin ka mea i hiki i ka myopathy. ʻO ka maʻi o ka myopathy (ʻo ka hōʻeha o ka ʻōpū a me nā nāwaliwali i hui pū me ka hoʻonui ʻana i ka hana CPK ma o ka 10 mau manawa i hoʻohālikelike ʻia me VGN) e kūkākūkā i nā mea maʻi me ka myalgia maʻamau, ʻehaʻeha naʻau a nāwaliwali a / a me kahi hoʻonui nui i ka hana CPK. Hoʻomaʻamaʻa ʻia nā mea maʻi e hoʻomaopopo koke lākou i ke kauka e pili ana i nā hiʻohiʻona ʻole o nā hōʻeha a me ka nāwaliwali o nā mākala inā e hele pū lākou me ka malaise a me ka maʻi maʻi. Pono e hōʻoki ʻia ka lāʻau Atorvastatin inā loaʻa ka māhina i hoʻonui ʻia i ka hana CPK a i ʻole inā i hōʻoia ʻia a i manaʻo ʻia ka myopathy. ʻO ka loaʻa ʻana o ka myopathy i ka mālamaʻana i nā lāʻau lapaʻau ʻē aʻe o kēia papa me ka hoʻohana pū ʻana i ka cyclosporine, fibrates, erythromycin, acid acid aot pe antifungal mai ka hui azole. He nui kēia mau lāʻau i ke hōʻemi ʻia e ka metabolism CYP3A4-mediated a me / a i ʻole ka lawe ʻana i ka lāʻau. Atorvastatin i biotransformed ma lalo o ka mana o CYP3A4. I ke koho ʻana i ka atorvastatin i hui pū me nā fibrates, erythromycin, immunosuppressive agents, azole antifungals, a i ʻole acidot aicine i loko o nā hopena hypolipidemic, pono ke loaʻa ka hopena kūpono a me ka hopena o ka mālama ʻana i nā maʻi a ʻike pono nā poʻe maʻi e ʻike pono i ka ʻike ʻana i ka hōʻeha ʻana a i ʻole nāwaliwali, ʻoiai ma nā mahina mua. ka mālama ʻana a me ka wā o ka hoʻonui ʻana i nā pohi o kekahi lāʻau lapaʻau. I kēlā mau kūlana, hiki ke ʻōlelo ʻia ke kau manawa holoʻokoʻa o ka hana KFK, ʻoiai ke pale ʻole ia i ka hoʻomohala i ka hoʻomohala ʻana i ka myopathy koʻikoʻi.

Ke hoʻohana ʻia nei i ka lāʻau Atorvastatin, a me nā lāʻau ʻē aʻe o kēia papa, ua hōʻike ʻia nā hihia o ka rhabdomyolysis me ka pale o ke kumu papalapa ma o ka myoglobinuria. ʻO ka hoʻōla ʻana o Atorvastatin, e hoʻokuʻu iki a hoʻomaha ʻole inā he mau hōʻailona hiki i ka myopathy a i ʻole ka hele ʻana o nā mea pilikia no ka hiki ʻana o ka renal ma muli o ka rhabdomyolysis (no ka laʻana, ʻoi loa ka maʻi maʻi, ka maʻi arterial, hoʻokō koʻikoʻi, trauma, hōʻeha metabola, endocrine a me nā hōʻaia electrolyte . ^ E Ha yM.

Ma mua o ka hoʻomaka ʻana i ka maʻi me ka Atorvastatin, pono ia e hoʻāʻo e hoʻokō i ka hoʻomohala o ka hypercholesterolemia ma o ka lawa ʻana o ka hoʻouka ʻana i ka papa, nui ka hana kino, ke kaumaha ʻana i ka mea maʻi me ka momona a me ka mālama ʻana i nā kūlana ʻē aʻe.

Hoʻomaʻamaʻa ʻia nā mea maʻi e pono koke lākou e kūkā i ke kauka inā ʻaʻole i loaʻa ka ʻeha a i ʻole nā ​​nāwaliwali o ka naʻau, inā ua hele pū lākou me ka malaise a me ka maʻi maʻi.

Hoʻokomo i ka hiki ke lawe i nā kaʻa a kāohi i nā mīkini

ʻO ka hopena maikaʻi ʻole o ka lāʻau Atorvastatin ma luna o ke hiki ke lawe i kahi kaʻa a hana pū me nā mīkini i hōʻike ʻole ʻia.

Hoʻomili hou a me ke ʻano hoʻohālikelike

Loaʻa Atorvastatin (i ka Lūkini - Atorvastatinum) i loaʻa i ka pepa papa wale nō. I mea e pale ai i nā hopena pōʻino o ke kaiapuni (ʻōwili, māmā, ke ana wela) i nā māhele o ka lāʻau lapaʻau, ʻo ia hoʻi no ka hoʻopiʻi ʻana i ka lāʻau lapaʻau ma ka ʻaoʻao o ka ʻōpū a me ka māhele mua o ka ʻōpū, ua uhi ʻia lākou me ka membrane kiʻi. Kūleʻa ka kala o ka kiʻiʻoniʻoni. Kahi maʻa ke keʻokeʻo, akā i kekahi manawa he melemele, ka ʻulaʻula a ʻulaʻula paha. ʻOkoʻa nō ka ʻano a me ka hiʻohiʻona o nā papa: he ʻolua a he capsule paha-ʻano, me ka pulu maalelia a i ʻole me ke kahakaha ʻana o nā helu ma nā ʻaoʻao ʻelua.

Akā ʻaʻole ka mea nui o ka lāʻau lapaʻau ka ʻike, akā mea waiwai. ^ E Ha yM. ʻO kēia ka atorvastatin calcium trihydrate. Akā no ka mea e pili ana ka kiko o ka atorvastatin i ka hana nui i ka hoʻokō ʻana i ka hopena therapeutic e pono ai, ua hoʻonohonoho pono ʻia ka nui o ka lāʻau. No laila ma ka pūnaewele kūʻai olakino hiki iāʻoe ke loaʻa i Atorvastatin me kahi kiko o 10, 20, 30, 40, 60 a me 80 mg o ka pūhui ikaika. ʻO nā hua liʻiliʻi ona (1 a me 5 mg), ʻoiai i loko o nā mea āpau hypolipidemic hui pū, ʻaʻole i noho.

Ma ka pahu pālani pila i 10, he 10 a 15 mau papa i kau ʻia. Hiki i ka palette hoʻokahi i loko o ka pākau, a ʻoi aʻe paha - hiki i ka 10. I mau pinepine ke loaʻa nā nui o nā papa i loko o nā kēke polymer. Aia nā hewa ʻē aʻe o nā lāʻau i kēia lāʻau mahiʻai, ka mea nui i ka atorvastatin. Akā ua loaʻa iā lākou kekahi, ʻaʻole i ka honua (INN), akā nā inoa kālepa (Atoris, Liprimar, Novostat, Tulip, etc.).

ʻO ka lāʻau kahiko Atorvastatin o ka hana Lūkia ma ka nnn e helu nei:

• ke code no ka hoʻonaninani anatomical and therapeutic chemical class (ATX) ʻo C10AA,
• code ma ke ʻano o ka helu ʻāina Lūkini OKPD2–20.10.149,
• e like me ka papa inoa o nā lāʻau lapaʻau o Lūkini (RLS), no ka huahelu i helu ʻia "statins" huaʻai.

ʻAʻole ʻo Atorvastatin wale ka hapa o ka lāʻau. Ka mea i loaʻa i ka poʻe hoihoi: calcium carbonate, cellulose, milk sugar, starch, silicon dioxide, magnesium stearate, polyvinyl alkohol, titanium dioxide, polyethylene glycol a me talc. Pono ka poʻe maʻi āpau e pili ana iā lākou, ʻo ka mea hiki ke hoʻomohala kekahi hopena ma ka microdoses o kēia mau pūhui.

Loaʻa ka Atorvastatin ma ke kau inoa inu, kahi i kau ai ke kauka ma ka ʻōlelo Latin. A inā paʻa nā mea lapaʻau ʻole ʻole e kūʻai aku i nā lāʻau lapaʻau, ʻaʻole pono ʻoe e lawe me ka ʻole e kūkā me ke kauka. ʻOiaʻiʻo, ma mua o ka mālama ʻana a me kāna hana e pono ai e mālama i ka hana o ka ate.

Nā hōʻailona no ka hoʻohana ʻana

ʻO nā kūlana i kau ʻia ai nā statins i kapa ʻia ʻo dyslipidemia. Ua unuhi ʻia i ka ʻōlelo maʻalahi, kēia ka momona o ka momona. ^ E Ha yM. ʻAʻole ia i ʻike mau iā ia iho no kahi manawa lōʻihi loa, a me ka neʻe pū ʻana o ka kolesterol "maikaʻi ʻole" i nā paia vascular e hana i nā hōʻailona atherosclerotic maʻamau e hoʻomaka. Ma ka hoʻomaka mua, ʻike ʻia ka nānā ʻole ʻana o lipid ma ka laboratory. Ua kapa ʻia ka loiloi, he lipid profile, ka mea e loaʻa ai nā mea nui o ka momona metabolism - triglycerides, kolesterol, ʻelua a me nā ʻāpana o ka nui o ka momona-protein, nā protein transporter protein, a me ka koina neʻe atherogen.

Ke koho ʻole nei i ka profile lipid (ka inoa lua o ka ʻōlelo lipid), hiki ʻole ke hoʻokū i ka dosage a me ke ʻano o statin, nā mea e lawaiʻa ʻia e ka mea maʻi i nā manawa lōʻihi (a, ʻo ia paha, i kona ola a pau). Eia kekahi, pono ka ʻōlelo lipid pono e mālama i ka mālama ʻana i hoʻomaka. Hāʻawi ʻia ke koko Venous no ka nānā ʻana ma hope o kahi hoʻomākaukau maʻalahi: inā ʻole ia, hiki ke hoʻokaʻawale ʻia nā hopena.

ʻO ka pono o ka atorvastatin ka mea e pono ai i ka mālama ʻana i nā ʻano o ka hypercholesterolemia āpau (loaʻa i ka hoʻoilina a loaʻa aku). Hoʻemi ia i ka pae o ka kolamu "kino" a me ka lawe ʻana i nā ʻōmua i hiki ke waiho i loko o nā paia o nā kīhaka. I ka manawa like, e hoʻonui i ka neʻe o ka lipoproteins "maikaʻi" a hoʻonui i ka nui o nā receptors e hopu i ka kolamu no ka ʻono a me ka hoʻohana ʻana. Eia kekahi, hoʻemi ʻo atorvastatin i ka triglycerides i loko o ke koko, akā ʻaʻole kēia e lawe i ka lawe no ke kaumaha.

Hoʻokumu ʻia ka mīkini o ka hana o ka hana ikaika i ka hoʻokau ʻana i ka hoʻoneʻe nui o ka hoʻoneʻe nui i kālai ʻia i ka hoʻokumu ʻana o ka cholesterol e nā poupuna o nā ate. The enzyme is called hydroxymethylglutaryl coenzyme A reductase, a me Atorvastatin, kēlā, kēia mea pale o HMG CoA reductase. ʻO kēia kūpono o ka lāʻau e hiki ke ʻae i ka mea e pani wale i ka ulu ʻana o nā pā pli atherosclerotic i kēia manawa, akā, ke pale pū ʻana hoʻi i ko lākou helehelena i nā kānaka me ka piʻi nui o ka ulu ʻana o ka atherosclerosis. No laila, hiki ke kuhikuhi ʻia no ka predisposition genetic i ka hypercholesterolemia i ka wā ʻōpio a i ʻole nā ​​mea hōʻino kaumaha a me nā maʻi maʻi hypertensive ma hope o 55 makahiki.

ʻAʻole mālama ʻo Statin i nā moku koko, akā me ka maʻi naʻau coronary a i ʻole aterosclerosis cerebral pale nā koi e like me naʻau a hōʻeha paha. ^ E Ha yM. ʻO nā ʻōpana no kona hoʻohana ʻana he mau huaʻeha o ka maʻi naʻau coronary, nā ʻano ma hope o nā mea, nā maʻi maoli cerebrovascular. Hoʻolaha ʻia ʻo Atorvastatin i ka manawa postoperative ma ka ʻepekema vascular a me ka cardiology. A loaʻa ka hopena maikaʻi loa me ka hoʻohana ikaika ʻana i ka lāʻau lapaʻau me nā lipid-haʻahaʻa haʻahaʻa a hui pū me nā ʻano hana ʻē aʻe e hoʻoponopono i ka momona o ka metabolism (kaʻai, ka hoʻohaʻahaʻa haʻahaʻa, hāʻawi i nā hana maikaʻi ʻole).

I ka wā hāpai a me ka lactation

ʻAʻole i lawelawe ʻia ka noiʻi ʻana i kēia kuhikuhi, ʻaʻohe mea e ʻike i ka pili ʻana o Atorvastatin i ka maʻi wahine a inā paha e komo ia i ka waiū umauma. No laila, ʻaʻole lākou i kuhikuhi ʻia i nā wahine hāpai, a inā pono pono e lawe iā ia i ka wā lactation, e hoʻololi ʻia ke keiki i ka hānai hana. I kēia mea, nā wahine o ka makahiki o ka hānau ʻana, ʻoiai e lawe ana i ka statin, ua hoʻolālā ʻia e hoʻohana i nā ala kūpono o ka kontrasept i mea e hoʻokō ai ka hopena o ka hapai ʻana i ka maʻi.

Atorvastatin i kuhikuhi wale ia no na pākeke, a manaʻo ia no ka mālama ʻana i ka maʻi metabolism lipid a no ka pale ʻana i nā hoʻopiʻi cardiovascular e pili ana i ke ʻano o ka atherosclerosis vascular ua ulu mua. ʻAʻole maopopo ka hopena o ka statin i nā keiki a me nā ʻōpio, no laila ʻaʻole pilikia ka poʻe kauka i ka hoʻohana ʻana i nā mea maʻi ma lalo o ka makahiki 18.

Nā hopena hopena

He haʻahaʻa ka hopena o ka hopena: i hiki i ka hopena ʻaoʻao ke 1-3% o nā hihia o ka hoʻohana lōʻihi ʻana o Atorvastatin.

1. ʻO ka hapa pinepine, ʻo kēia mau hōʻailona neʻeneʻeli ma ke ʻano o ka ʻōpū, ke poʻo, a me nā maʻi tigā o ka maʻi.
2. Ma muli o ka manaʻo o ka waiwai ola e hoʻopili ai i ka palupalu, hiki i ka dyspepsia ke ulu - ulu i ka uhi, maʻi, ka ʻōpū, ke aʻa paha ka constipation, ʻeha ma ka ʻōpū.
3. I kekahi manawa he mau maʻi hōʻeha hōʻemi.
4. Ke kāhea nei ke aʻo i nā maʻi kūlohelohe (mai ka hōʻeha o ka ʻili i ka anaphylaxis), he hoʻemi i ka potency, he hōʻoki i ka naʻau o ka nīnipeka peripheral, cramps, a me nā hōʻeha puʻupuʻu e like me nā hopena ʻokoʻa rarer.
5. Maʻalahi loa ka hoʻomohala ʻana i ka maʻi hepatitis a me ka pancreatitis, nā loli i loko o ke ʻano o ke koko e hele nei: kahi hōʻemi o ka nui o nā platelets, hoʻonui i ka pae o ka huina o ka huina.
6. Ma nā hihia kaawale, ua hoʻopaʻa ʻia ka rhabdomyolysis - ka luku ʻana i nā hua māi me ke kāohi ʻana o nā tubula māla ma o kā lākou hana decompposation, e alakaʻi ana i ka maikaʻi ʻole o ka renal.

Pono e hāʻawi ʻia ka ʻike kūikawā i nā maʻi maʻi maʻi mau ʻano 'elua. ʻO ka angiopathy Diabetic kahi hōʻike hōʻike i ka maʻi. A eia kekahi, ʻaʻole ka wikiwiki o ka loiloi o ka atherosclerotic vascular. Ua kuhikuhi ʻia ʻo Atorvastatin i nā maʻi maʻi maʻi i ka wā i ʻike ʻia ai ka dyslipidemia. E hoʻohāʻī i ke kō koko? He kūmole ka pane: he ʻokoʻa nā mea āpau; ʻaʻole i pili ka lāʻau lapaʻau i nā kiʻekiʻe glucose, akā hiki i ka liʻiliʻi o ka hypo- a i ʻole hyperglycemia. ʻO ka hoʻohana ʻana o ka statin therapy no ka maʻi type a me ka type 2 e pili ana i ka mālama pinepine ʻana i nā puna.

ʻLoe a me ke kākele

Hoʻoholo ʻia ka nui o ka lāʻau lapaʻau e ke kauka, ma muli o ka pae a me ke ʻano o ka dyslipidemia. Ua hoʻoholo pū ʻo ia i ehia mau mahina a i ʻole mau mahina ma hope o ka mālama ʻana. Pēlā i hoʻohālikelike ʻia a i ʻole nā ​​lāʻau lapaʻau i kauoha ʻia no ke kolamu kiʻekiʻe, a me kahi kīʻaha lipid-hoʻemi ʻana i ka meaʻai i ka wā e lawe ai iā lākou, hiki ke kuhikuhi. E aʻo aku ka mea loea i ka inu ʻana i ka wai maʻemaʻe a me ka hoʻohālikelike ʻana i nā hana kino.

Eia nō naʻe, pono e ʻike ka mea maʻi i ka manawa o ka lā ʻoi aku ka maikaʻi e lawe i ka lāʻau lapaʻau (kakahiaka a i ke ahiahi) ma mua o ka inu ʻana, inu kīwī ma mua o a ma hope o ka ʻai.

1. ʻAʻole i hilinaʻi ʻia ka pae a me ka pae o ka hōʻemi o ka "bad" kolesterol i ke koko i ka komo ʻana o ka meaʻai.
2. ʻO ka ʻike ʻana o ka hana ikaika i loko o ke koko he 30% ʻoi aku ke kiʻekiʻe me ke kō ʻana o ke kakahiaka i nā papa, hoʻohālikelike ʻia me ke ahiahi.Akā, kahi lāʻau lapaʻau i ka pō i loaʻa ka hopena i ka nui o ka ate, ka mea e ʻoi aku ka ikaika i ka pō. No laila, ʻaʻohe mea ʻē i ka manawa o ka lā e lawe ʻia ai ka papa papa. ʻO ka mea nui i ka manawa like.
3. No ka luhi maʻalahi o ka lāʻau ma o ke kaomi hana ʻana, ʻoi aku ka maikaʻi e inu me ka wai maʻemaʻe. Hiki iā ia me kekahi mea ʻē aʻe, akā ʻaʻole me ka wai ʻōpala, ka mea e hoʻonui ai i ka ʻike ʻana o ka statin a laila e hoʻonui ai i kona paʻa ʻana i ke koko.
4. Hoʻomaka ka Therapy me nā liʻiliʻi liʻiliʻi (10 mg), a ma hope o 2, 3 a 4 paha mau pule e kau ʻia ai kahi hoʻolaha lipid. ʻO kēia ke kumu i hoʻomaka ai ka hopena therapeutic e hōʻike wale iā ia ma hope o ka hopena o ʻelua pule, a hiki i ka hopena nui loa i ka hopena o ka mahina. Wahi a ka ʻōlelo lipid, alakaʻi ke kauka i ke ʻano o ka hoʻololi ʻana i ka dosage.
5. Pākuʻi loa ka nui o Atorvastatin i ke ʻano o ka dyslipidemia, me kāna helu helu mua, ka manawa / ka hala ʻana o ka pathology ate, a me ka hoʻokele ʻana o nā lāʻau lapaʻau o nā ʻāpana ʻē aʻe. Aia nō i ka manawa pehea a ia e lawe ai.

Nā hiʻohiʻona noi

Ma mua o ka kuhikuhi ʻana i ka Atorvastatin, ke ho'āʻo nei nā kauka e hoʻokō i ka hoʻihoʻi hou o ka lipid kūloko ma o kaʻai ʻana, ka hana kino, hōʻemi kaumaha. I ka ʻoiaʻiʻo, hoʻomau kēia ʻano hana i loko o ke kaʻina hana a pau o statin. Ma mua koke o ka loaʻa mua o ka lāʻau lapaʻau hana ate. ^ E Ha yM. A laila lilo ia i mau loa: ʻo 1.5 mau pule ma hope o ka hoʻomaka ʻana o ka lapaʻau, ma hope o 3 mau mahina, a laila - i kēlā me kēia ʻeono mahina a ma hope o kēlā me kēia loli i ka makeʻe.

Eia kekahi, e nānā ʻia nā hoʻoponopono regrens no nā maʻi concomitant ma mua o ka hoʻomaka ʻana i ka ʻoihana. Me ke kiʻekiʻe o ke koko, ka hypothyroidism, obesity, pathology ate, koho ʻia nā lāʻau lapaʻau a i ʻole ka dosage i hoʻohana ʻia, e like me ka annotation. Eia kekahi, ua ʻōlelo ʻia ka maʻi maʻi e pili ana i ka hiki ʻana o myopathy, a no laila pono lākou e hoʻomaopopo i kā lākou kauka i kekahi ʻeha hōʻeha.

Ke papa haʻahaʻa ʻaʻole hana ʻia ka hoʻomaʻamaʻa ʻana no kekahi mau lā, a e lōʻihi e like me ka ʻōlelo ʻana a ka loea. ʻO ka maʻamau ka liʻiliʻi o kekahi mau mahina. Ma hope o nā mea a pau, hoʻomohala ʻia ka lipid hiki i nā makahiki a keu paha paha. A e lilo i manawa lōʻihi e hoʻoponopono. No laila, ʻo ka nīnau inā hiki iā ʻoe ke hoʻomaha i kāu iho pono iho: ʻaʻole pono e inu ʻokoʻa nā papa. Ma kahi o ka haki, hiki ke lawe ʻia ʻo Atorvastatin no mau makahiki, a pehea ka lōʻihi e hana ai ia mea i kēlā me kēia hihia - e haʻi ka ʻōlelo lipid.

Me ka hana pūpū hemahema

ʻAe ʻia ka Atorvastatin i ka haʻalele ʻana o ka pathology ate a me ke ʻano maʻalahi o ka hāʻule ʻole o ka ate. Eia naʻe, ke loiloi nei i ka pono no kona hoʻohana a me ka hiki ke hoʻololi hou i nā ʻano ʻē aʻe e pili ʻole ai i ka ate. ʻO ka nānā ponoʻana i ka hana hana o nā hepatocytes i ka hihia o ka pale ʻana o ka nui o ka mea nui. Pono e hana nā loiloi i ka manawa a ma hope o ka hoʻomākaukau ʻana.

Ka lāʻau kūʻai lāʻau

Hoʻololi ʻia nā lāʻau lapaʻau o kēia pūʻulu pharmacological i nā'āina he nui, a ʻo ke kumukūʻai o Atorvastatin i hilinaʻi i ka mea hana. Eia nō naʻe, me ka dosage i milligrams, a ma ka nui o nā papa i ke kaʻe. ʻO nā hui i ke kumukūʻai he hoʻomākaukau no nā hana ma Ukrania, Lusia, India a me ka hana English.

ʻO ke kumukūʻai o ka papa papa malama me kahi lā he 20 mg i kā mākou mau lāʻau lapaʻau ma waena o 90 ± 20 UAH. a i ʻole 250 ± 80 mau rubles. ʻO nā papa pōpilikia o ka ʻIseraʻela he 1.5 mau manawa hou aku, ʻoi aku ka nui o nā manawa Spanish, ʻo ʻAmelika a me Kelemania he mau manawa 3-4 ka uku

Nā mea inoa a me nā mea e hoʻololi ai no ka Atorvastatin

ʻO ka lāʻau pana mua ʻaʻole ia o kekahi ʻano. E pili ana i ke kumu hana nui, hana ʻia ka nui hoʻohaʻahaʻa me nā mea like (no ka laʻana, Atoris, Atokor, Atormak a Atorvoks) paha, a i ʻole holoʻokoʻa ʻē aʻe (Torvakard, Tulip, Vazator), nā inoa kālepa e ʻokoʻa ana i ka hoʻopili ʻana o nā mea hoʻohui. ʻOi aku kekahi o lākou, he mea ʻoi aku ka uku. Hiki iā lākou ke hoʻohuli ʻia e kekahi, akā me ka ʻike i ke kauka e hele mai ana.

ʻOi ka statin e pili ana i atorvastatin

Ma ka pale lāʻau lapaʻau, pinepine ma hope o ka inoa inoa inoa he mea pōkole a i ʻole kekahi ʻōlelo ʻē aʻe, no ka laʻana, ʻo Atorvastatin SZ a i Atorvastatin MS. Hōʻike kēia mau māhele i nā mea hana like. I kēia mau hihia, ke kamaʻilio nei mākou e pili ana i nāʻoihana lapaʻau Lūkini nui ʻo Severnaya Zvezda a me Medisorb. Ma nā pōkole ʻē aʻe hiki iā ʻoe ke ʻike i nā huaʻōlelo hou "Pranapharm", "Ozone", "LEXVM", "Vertex", "Canonfarm", "Akrikhin", "Actavis", "Biocom", "ALSI Pharma".

Ma waena o nā hui kikoʻī hiki iā ʻoe ke ʻike i Atorvastatin Alkaloid (Makedonia), Atorvastatin Teva (Israel), Ananta (India), Pfizer (USA), Blufish (Sweden), Ratiopharm (Germany), " Aveksima "(ʻoihana hui) ... ʻAʻole hiki ʻole ke hōʻoia pono e ʻōlelo i ka lāʻau a nā ʻoihana e ʻoi aku ka maikaʻi. ʻOiai, nā ʻenehana kēia, nā mea kikoʻī pololei. Aia nā loina i kapa ʻia ʻo Atorvastatin i ka waiwai like. ʻOkoʻa lākou i nā mea kōkua kaukaʻi: hiki ke hoʻololi ʻia nā papa me ka hoʻohana ʻana i nā mea i ʻoi aku ka hopena i loko o kahi hoʻoponopono mālama lāʻau hoʻokahi. Akā, e like me nā lāʻau lapaʻau atorvastatin me nā inoa kālepa ʻē aʻe.

Hōʻoia ʻia kēia e nā loiloi o nā loea a me nā mea maʻi: nā maʻi lapaʻau maikaʻi i hoʻokumu ʻia ma ka atorvastatin i koho ʻia no nā mea maʻi, a ʻaʻole i pili i ka hopena i nā hopena o ka ʻōlelo lipid. Akā, ʻaʻohe mea i pōmaikaʻi i ka hoʻopili pihaʻana i nā huahana pharmacological me nā mea hoʻoponopono kūlohelohe.

ʻO ka ʻokoʻa ma waena o ka atorvastatin a me rosuvastatin, simvastatin a me lovastatin

ʻO ka lāʻau ma lalo o ke kūkākūkā e pili ana i nā statins statins o ke kolu o ka hanauna. Ma lalo iho i ka laulā a ʻoi aku ka manawa i ke komo ʻana i ka hoʻomaʻamaʻa therapeutic, synthetic fluvastatin, semi-synthetic simvastatin a pravastatin, a me ka aloha lovastatin. ʻO nā mea hou e pili ana i ka hypolipidemic hou e loaʻa i nā lāʻau synthetic o nā hanauna hou o Pitavastatin a me Rosuvastatin. He aha ka ʻokoʻa ma waena o lākou?

Hoʻokumu ʻia ʻo Lovastatin ma ke kumu o nā huahana koʻikoʻi o nā fungi aspergillus. He pilikia ka hōʻino ʻana, lawe i ka manawa a ʻaʻole pono ka hoʻopukapuka kālā. Hoʻohana ʻia nā lako pahala like i ka hana hana o Simvastatin a me Fluvastatin. ʻO kēia mauʻikena he mau huahana: hana ka metabolites i ka lipid metabolism, ʻaʻole pono iā lākou iho. No laila, pono kekahi mau manawa o ka wā i loaʻa ai ka hopena i makemake ʻia. Ma kahi hoʻohālikelike, ʻo ʻAtorvastatin, ʻo Pitavastatin a i ʻole Rosuvastatin ua mākaukau e hakakā ke koloka "hewa" koke koke ma hope o ke komo ʻana i ke kahawai.

ʻO kahi kūlana like me ka pae a me ka wikiwiki o ka mana o ke kino: nā lāʻau lapaʻau o 3 a me 4 mau hanauna i ʻoi aku ka maikaʻi (Simvastatin - 2 mau manawa, Pravastatin a me Lovastatin - 4 mau manawa, Fluvastatin - 8 mau manawa). Eia nō naʻe, he mea makemake nā kauka a me nā mea maʻi e like ʻoi aku ka palekana. A laila pau ke kākoʻo āpau i ka ʻōlohelohe o ka lāʻau. ʻO ka momona-soluble lovastatin, simvastatin, a me atorvastatin e maʻalahi e komo i nā pehu o nā lolo. A ʻo nā hopena ʻaoʻao mai ke kaena o ka nūnū o ka pokela, ʻoi aku ka ʻoi aʻe ma mua o ka wai-wai piha rosuvastatin, fluvastatin a me pravastatin. Akā ʻo ka hopena hope loa i ka hopena o nā pūpū o nā puʻupaʻa, e hiki ke hōʻike ʻia e ka piʻi nui o ka pae o nā ate o ka ate i ke koko.

Inā mākou e hoʻohālikelike i nā lāʻau lapaʻau o nā hanauna hou me kēlā me kēia, ʻo ka mea nui e hoʻokaʻawale i ke Atorvastatin mai Rosuvastatin a me Pitavastatin he maikaʻi ʻole (2 mau manawa) a, pēlā, a me kahi papa liʻiliʻi o nā hanana ʻino. Eia kekahi, ʻo ka ʻike ʻana o nā lāka hou loa i loko o ke koko ʻaʻole i loaʻa i ka ʻai meaʻai, ʻoiai e pili ana nā kumuhana o nā statins i ka manawa o ka ʻai ʻana i ka ʻai.

ʻO Lovastatin, Simvastatin a i Atorvastatin, ʻo Rosuvastatin: ʻoi aku ka mea o lākou e ʻōlelo e ke kauka. Akā mai ka hiʻohiʻona o ka lāʻau lapaʻau e pili ana i ka hōʻike, ua hāʻule ka koho i nā statins me ka synthetic active ingredients atorvastatin a i rosuvastatin. ʻO kēia ka mea ʻo Rosart, Rosucard, Mertenil, Crestor, Suvardio, Cardiolip a me nā mea ʻē aʻe he nui. Akā inā manaʻo nā mea maʻi e lawe i nā lāʻau lapaʻau wale nō ma ke kumu o nā lāʻau lapaʻau, a laila hoʻopau ka ʻoki manu (Ateroklefit Evalar) i kahakaha synthetics.

Nā Hōʻike Hoʻohana

Nui nā poʻe, ma mua o ka hoʻomaka ʻana i ka mālama ʻana, makemake e ʻike i ka manaʻo kūʻokoʻa o nā kauka (nā mea lapaʻau, cardiologists), ʻo ia hoʻi e kamaʻilio me nā loiloi o nā mea maʻi i lawe i kēia lāʻau statin. Ma hope o ka hoʻokolokolo ʻana o nā loea a me nā maʻi maʻi, hiki i kekahi ke kiʻi i kēlā mau ʻōlapa.

• ʻO Atorvastatin ka lāʻau lapaʻau e koho ai no nā kauka he nui ma muli o kona kūlana maikaʻi a me nā hopena kūlohelohe nui,
• ka hapa nui o nā poʻe maʻi e lawe nei i ka pills no ka "kino" kolesterol i ka hoʻomaikaʻi ʻana i ka maikaʻi, ʻoi loa nā poʻe e pono ke hoʻololi i ka hanauna hou o statin me ka rosuvastatin me ka atorvastatin ma muli o nā hopena maʻamau.
• he helu liʻiliʻi wale nō nā mea maʻi i ka wā e lawe ai i ka lāʻau lapaʻau e hoʻopiʻi ana i ka maʻi palupalu, nāwaliwali a me ke poʻo, akā, he mau kānaka kahiko kēia i kuhikuhi ʻia i nā helu kiʻekiʻe o ka lāʻau.