Ke huahana Glemaz: kuhikuhi i ka hoʻohana

Ka puka ʻana - nā papa: ʻāpana, ʻākala, kukui ʻōmaʻomaʻo ma ke kala, me 3 mau ʻaukā pākuʻī i kau ʻia ma ka laulā o ka papa ma nā ʻaoʻao ʻelua a hoʻohele ʻia i nā ʻāpana like 4 (5 a i ʻole 10 mau ʻāpana i loko o kahi kīwī, i loko o kahi pā o ka pahu 3 a 6 mau blisters )

ʻO kēia papa hana: glimepiride, i 1 papa - 4 mg.

Nā kumuwai hou: microcrystalline cellulose, magnesium stearate, cellulose, croscarmellose sodium, polina ʻulaʻula nani, ʻeleʻele dile melemele.

Nā Hoʻohui

• ʻAno maʻi type 1
• Leukopenia
• Hōʻeha ka pilikia o ka renal maʻi (me ka contraindicated no nā mea maʻi ma ka hemodialysis),
• Kanaka kūpeʻe pale,
• ʻO ka precoma Diabetic a me kahi coma, ketoacidosis maʻi,
• ʻO nā kūlana me ka malabsorption o ka meaʻai a me ka hoʻomohala ʻana o ka hypoglycemia (me nā maʻi hopohopo),
• Ke lalo o 18 mau makahiki
• ʻŌpū a me ka lactation
• ʻO ka hypersensitivity i nā mea o ka lāʻau lapaʻau a iʻole nā ​​derivatives sulfonylurea a me nā mea kanu sulfonamide.

Pono e hoʻohana ʻia ʻo Glemaz me ka akahele i nā kūlana e koi ai i ka hoʻololi ʻana o ka mea maʻi i ka hoʻomehana ʻana o ka insulin, e like me ka malabsorption o ka meaʻai a me nā lāʻau i ka ʻeha gastrointestinal (e komo pū ana i ka gastes paresis a me ka pākī o ka ʻōpū), nā hana hōʻeha nui, nā hōʻeha huhū nui, ʻā nui.

ʻLoe a me ke kākele

Lawe ʻia a Glemaz. Pono ka ʻai ʻia o kēlā me kēia lā i loko o hoʻokahi hapa ma mua a i ʻole i ka wā o ka ʻaina kakahiaka a i ʻole ka kīʻaha mua. Pono e ʻōlelo ʻia nā papa me ka ʻole o ka nalo ʻana, holoi ʻia me ka nui o ka wai (ma kahi o ½ kīʻaha). Ma hope o ka lawe ʻana i ka paila, ʻaʻole ia e ʻōlelo ʻia e skipī i kahi pāʻina.

Hoʻoholo ka pakanā mua a me ka mālama mālama i kēlā me kēia ma muli o nā hopena o ka hoʻoholo maʻamau o ka neʻe o ka glucose i loko o ke koko.

I ka hoʻomaka ʻana o ka hoʻōla, ʻo ka 1 mg o ka glimepiride e kuhikuhi maʻamau (1 /₄ papa) 1 ka manawa i kēlā me kēia lā. Inā hiki ke hoʻokō i ka hopena therapeutic maikaʻi loa, e hoʻomau ʻia ka lāʻau lapaʻau i loko o ia mau ka hopena (ma ke ʻano he mālama mālama).

Ma ka haʻalele ʻana o ka mana glycemic, e hoʻonui pinepine ʻia ka nui o ka lā i ka neʻe ʻana, mālama mau i ka ʻike ʻana o ka glucose i ke koko: i kēlā me kēia 1-2 mau pule, mua a hala i 2 mg, a laila e piʻi i ka 3 mg, a laila e piʻi i ka 4 mg (nui kahi kō ma lalo o 4 mg i nā hanana kūikawā ) ʻO ka pae pae ʻokoʻa loa ka lā no 8 mg.

ʻO ka manawa a me ka pinepine o ka lawe ʻana i ka lāʻau lapaʻau e hoʻoholo ʻia e ke kauka ma muli o ke ʻano o ka mea maʻi. Pono lōʻihi ka mālama ʻana, e kaohi e ka glucose o ke koko.

Hoʻohana me ka hui pū me ka metformin

Inā ʻaʻole hiki ke hoʻokō ʻia ka mālama glycemic i nā maʻi e lawe ana i ka metformin, e kuhikuhi pū ʻia ka lāʻau hui pū me Glemaz. Ma kēia hihia, mālama ʻia ka nui o ka metformin ma ka pae like, a me ka glimepiride e kuhikuhi i ka pae liʻiliʻi loa, ma hope o ka manawa e hoʻonui iki ʻia i ka nui o kēlā me kēia lā (e pili ana i ka ʻaila o ka glucose i ke koko). Ke hana ʻia nei ka lāʻau hui ʻana ma lalo o ka mākaʻi lāʻau olakino.

Hoʻohana me ka insulin

Inā loaʻa nā mea maʻi i ka Glemaz ma ke kikoʻī loa ma ke ʻano he lāʻau hoʻokahi a e hui pū me ka nui loa o ka metformin hiki ʻole ke hoʻokō i ka glycemic control, hiki ke kuhikuhi ʻia i ka hui ʻana me ka insulin. Ma kēia hihia, ke waiho ʻia nei ka hopena o ka glimepiride hope loa, a ʻōlelo ʻia ka insulin ma ka palena liʻiliʻi ma a inā pono, e hoʻomāhuahua iki ʻia ma lalo o ka hoʻomalu o ka ʻaila o ka glucose i ke koko. Hoʻohālikelike ʻia ka hoʻomaʻamaʻa ʻana ma lalo o ka nānā mālama olakino.

Ka hoʻololi i ka mea maʻi i Glemaz mai kekahi lāʻau lapaʻau hypoglycemic waha

Ke hoʻihoʻi nei i ka mea maʻi mai kahi lawehala hypoglycemic waha, ʻo ka hopena mua o ka glimepiride e pono ka 1 mg, ʻoiai inā i lawe ʻia kahi lāʻau lapaʻau e loa ʻia ma ka nui loa. Inā pono, i ka wā e hiki mai ana, e hoʻonui ʻia ke ʻano o Glemaz e like me nā ʻōlelo aʻo i hōʻike ʻia ma luna aʻe a manaʻo i ka hana pono, pākahi a me ka lōʻihi o ka hana a ka lāʻau lapaʻau hypoglycemic pili. I kekahi mau hihia, ʻoi aku ka wā e hoʻohana ai i ka lawehala hypoglycemic me ka hapa hapa o ke ola lōʻihi, pono ia e hoʻopau iki i ka mālama iki (no kekahi mau lā) i mea e pale aku ai i ka hopena hoʻohui e hoʻonui i ka hōʻeha o ka hypoglycemia.

Ka hoʻololi i ka mea maʻi mai ka insulin i ka glimepiride

I nā ʻokoʻa kūʻokoʻa, ke hoʻokō nei i ka therapy insulin i nā poʻe maʻi me ka diabetes mellitus type 2, aʻo ka uku no ka maʻi a me ka hana huna i mālama ʻia i nā seleka pancreatic,-sel, hiki ke loli ke ʻano me ka glimepiride. Hoʻomaka ka ʻike ʻo Glemaz ma kahi liʻiliʻi loa o 1 mg, lawe ʻia ka hoʻoneʻe ʻia ma lalo o ka mākaʻi loea olakino.

Nā hopena hopena

• Metabolism: ke ʻano wahaheʻe hypoglycemic e hele kokoke mai nei ma hope o ka lawe ʻana i ka lāʻau (hiki iā lākou ke loaʻa kahi ʻano koʻikoʻi a me ke ʻano, ʻaʻole hiki ke neʻe iki ʻia),
• Pūnaehana digestive: ʻeha o ka ʻōpū, ka manaʻo ʻana o ke kaumaha a i ʻole ka ʻāʻī ma ka epigastrium, ʻāhaʻi, ka luaʻi, ka ʻeha, ka ʻuala, kolestasis, ka hana nui o ka transaminases hepatic, hepatitis (a hiki i ka hoʻopiʻi ʻana o ka ate).
• ʻO ka ʻōnaehana hematopoietic: aplastic a hemolytic anemia, erythrocytopenia, leukopenia, granulocytopenia, pancytopenia, agranulocytosis, thrombocytopenia (i ke kāʻei i ka kaumaha).
• Pūnaewele o ka hihiʻo: ʻoi aku ka pinepine ma ka hoʻomaka ʻana o ka hana maʻi - ʻike kino ʻole i ke kahe ʻana,
• He hopena alerika: urticaria, ʻili keokeo, ʻeha (maʻa mau ke kau ʻana, akā hiki ke holomua, i hele pū me ka pōkole o ka hanu a hoʻohaʻahaʻa i ke koko, alakaʻi i ka pīhoihoi anaphylactic), cross-allergy me sulfonamides a me nā sulfonylureas a i nā mea like, like me ka vasculitis allergic,
• Nā kumuhana hou: i kekahi mau hihia - hyponatremia, asthenia, photosensitivity, ʻeha, hōʻeha o ka ʻili o ka pehu.

Nā ʻōlelo kikoʻī

Pono e hoʻopili ʻia ʻo Glemaz e like me nā ʻōlelo a ke kauka. ʻO nā hewa hala (no ka laʻana, hemo i ka wai i hope) ʻaʻole hiki ke hoʻopau ʻia e ke ʻano hou aʻe o kahi kiʻekiʻe kiʻekiʻe. Pono ke kamaʻilio e kūkākūkā me ke kauka ma mua o nā hana e pono ai e mālama i ka hewa o nā kuhi hewa ʻole a i kahi kūlana paha inā ʻaʻole hiki ke loaʻa nā kaha hou i ka manawa i koho ʻia. Pono e haʻi aku ka mea maʻi i ke kauka inā loaʻa iā ia kahi papa kiʻekiʻe.

ʻO ka hoʻomohala ʻana o ka hypoglycemia ma hope o ka lawe ʻana iā Glemaz i kēlā me kēia lā o 1 mg ʻo ia ka mea e hiki ke mālama wale i ka glycemia ma kaʻai.

Ke loaʻa ka uku uku no ka maʻi diabetes type 2 e hoʻonui ʻia ka hoʻonui ʻana o ka insulin, no laila e koi ʻia kahi hōʻemi o ka glimepiride. I mea e pale ai i ka hoʻomohala ʻana o ka hypoglycemia, pono ʻoe e hōʻemi i ka waʻa iki a hoʻopau ʻole iā Glemaz. Pono ka hoʻololi ʻia ʻana o ka hana me ka loli ma ke kaumaha o ke kino, ke ola, a i ʻole nā ​​mea ʻē aʻe e alakaʻi i ke kūkulu ʻana o ka hyp- a i ka hyperglycemia.

Pono ka nānā pono ʻana o ka mea maʻi i nā hebedoma mua o ka mālama ʻana, no ka mea ʻO ia i ka manawa o ka hopena i ka uluʻana o ka uluʻana o ka hypoglycemia e hoʻonui. Loaʻa kahi ʻano like i ka wā e ʻaʻai ai i ka ʻai a ʻai paha i ka meʻe ʻole.

Pono e noʻonoʻo pono e hōʻiliʻili ʻia nā hōʻailona o ka hypoglycemia a i ʻole hele i ka poʻe kahiko, nā mea maʻi me ka neuropathy autonomic a me nā mea maʻi e loaʻa ana iā beta-blockers, reserpine, clonidine, guanethidine. Hiki i ka ʻōmaʻomaʻo o ka hypoglycemia ke kokoke koke i ka hoʻokeo koke ʻia i ka ʻai (gula a me ke kōpaʻa, no ka hoʻohālikelike ʻana, me nā hua pāpaʻi, nā wai momona a i ʻole nā ​​wai ʻona. No kēia kumu, ua hōʻike ʻia e loaʻa i nā mea maʻi i ka liʻiliʻi o 20 g ka glucose (4 mau ʻāpana o ka gula i hoʻolaʻa ʻia) me lākou. ʻO nā mea momona loa i ka mālama ʻana i ka hypoglycemia hikiʻole.

ʻO ka manawa holoʻokoʻa o ka mālama ʻana me Glemaz, pono e kiaʻi pinepine i ka hoʻokaʻawale o ka glucose i loko o ke koko, ka pae o ka hemoglobin glycosylated, hana kino, ke kiʻi o ke koko peripheral (ʻoi aku ka nui o nā platelets a me nā keʻena koko keʻokeʻo).

I nā kūlana koʻikoʻi (no ka laʻana, me nā maʻi ʻeha me ke kuni ʻana, ka hana a i ʻole ka trauma) paha, he pono ka hoʻolilo ʻana o ka mea maʻi i ka insulin.

I ka wā o ka mālama ʻana, pono e hoʻomaʻamaʻa ʻia i ka wā e komo ai i nā hana hiki i ka pōpilikia, ka hana e koi ʻia ai ka nui o ke ʻano o ka hopena a me ka mālama nui (ʻoiai ke alakaʻi i nā kaʻa).

Hoʻohui nūhou

Me ka hoʻohana like ʻana o Glemaz me nā lāʻau lapaʻau ʻē aʻe, he mea hiki ke loli - e hoʻoikaika ana ʻole i ka nāwaliwali paha. No laila, hiki i ke kiʻi ke lawe i kekahi lāʻau lapaʻau e ʻae pū me kāu kauka.

Ke hoʻoikaika nei i ka hana hypoglycemic o Glemaz a, ma muli o ke ʻano, ʻo ka hoʻomohala ʻana o ka hypoglycemia hiki ke hōʻuluʻulu i ka hoʻoulu ʻana me nā lāʻau lapaʻau e hiki mai ana: insulin, metformin, nā huaʻōlelo hypoglycemic waha, angiotensin e hoʻohuli ana i ka enzyme inhibitors, anabolic steroid and male sex hormones, monoamine oxidase inhibitors, salicylates (in waikawa), nā ʻenehana antimicrobial - derivatives quinolone, tetracyclines, sympatholytics (me ka guanethidine), kekahi mau hana sulfonamides lōʻihi, etc. coumarin nā mea loaʻa, fibrates, allopurinol, trofosfamide, fenfluramine, ifosfamide, fluoxetine, miconazole, cyclophosphamide, chloramphenicol, oxyphenbutazone, tritokvalin, azapropazone, fluconazole, sulfinpyrazone, phenylbutazone, pentoxifylline (lawelawe parenterally ma kiʻekiʻe nā māhele).

ʻO ka nāwaliwali o ka hana hypoglycemic o Glemaz a, me ka hopena, ke piʻi ʻana o ka ʻike o ka glucose i loko o ke koko, hiki ke hoʻoulu ʻia i ka hui pū ʻana me nā lāʻau e like me kēia: glucocorticosteroids, thiazide diuretics, laxatives (me ka lōʻihi o ka hoʻohana), estrogens a progestogens, barbiturates, epinephrine a me nā ulama hou. nikotinic acid (i nā helu koʻikoʻi) a me nā mea waiwai o ia, glucagon, diazoxide, acetazolamide, nā derivatives phenothiazine, komo chlorpromazine, rifampicin, phenytoin, paʻakai lithium, nā hormone thyroid.

Reserpine, clonidine, histamine H blockers₂nā mea hoʻoneʻe hiki ke hoʻowalewale i ka hopena o ka hypoglycemic hopena o ka glimepiride. Ma lalo o ka hopena o kēia mau lāʻau a me ka guanethidine, kahi nāwaliwali a hōʻino piha ʻole paha i ka hōʻailona o ka maʻi hypoglycemia hiki.

Hiki i ke Glimepiride ke hoʻonalo a hoʻomaikaʻi paha i ka hopena o nā derivatives Coumarin.

I ka hihia o ka hoʻohana like ʻana o nā lāʻau lapaʻau e ʻoki ana i ka hematopoiesis pumehana o ka iwi, hoʻonui ka ulu ʻana o ka myelosuppression.

Hiki i ka hoʻohana a hoʻokahi kūlohelohe ia i nā mea ʻawaʻawa hiki ke hoʻoikaika a hoʻonāwaliwali i ka hopena hypoglycemic o Glemaz.

ʻO nā mea hoʻohālikelike o ka lāʻau Glemaz: Amaryl, Glimepiride, Glimepiride Canon, Diamerid.

Nā ʻōkuhi no ka hoʻohana ʻana iā Glemaz (ke ʻano a me ka helu ana)

Lawe ʻia nā papa Glemaz ma ke ʻano hoʻokahi ma mua o a i ka wā o ka ʻaina kakahiaka, a i ʻole ka ʻai mua. Lawe i nā papa ʻaina piha, mai kolo, inu i nā ʻano wai he nui (ma kahi o 0.5 mau kīʻaha). Hoʻonohonoho ʻia ka dosage i kēlā me kēia ma muli o nā hopena o ka mālama pinepine ʻana i ka kaʻe koko.

Initial dosis: 1 mg 1 manawa i kēlā me kēia lā. Ke hoʻokō nei i ka hopena therapeutic maikaʻi loa, e hōʻike ʻia e lawe i kēia kaha ma ke ʻano he mālama mālama.

Ma ka haʻalele ʻana o ka mana glycemic, hiki i ka nui ke hoʻonui i ka wai i kēlā me kēia lā (me ka nānā pinepine ʻana o ka nānā ʻana i nā kaila glucose o ke koko ma waena o 1 a 2 mau pule) i ka 2 mg, 3 mg a i ʻole 4 mg i kēlā me kēia lā. Hiki ke kuhikuhi ʻia nā hala ma lalo o 4 mg i kēlā me kēia lā.

ʻO ka laʻau ʻāpono nui i kēlā me kēia lā: 8 mg.

Ka papa hana o ka mālama ʻana: no ka manawa lōʻihi, ma lalo o ka kaohi o ka glucose koko.

Hoʻohana me ka hui pū me ka metformin

I ka haʻalele ʻana o ka mana glycemic i loko o nā mea maʻi e lawe ana i ka metformin, hiki ke mālama ʻia ka maʻi concomitant me glimepiride.

ʻOiai ke hoʻomau nei i ka makeʻana o ka metformin ma ka pae like, hoʻomaka ka lāʻau me ka glimepiride me ka liʻiliʻi haʻahaʻa, a laila e hoʻonui mālie ka nui o ke ʻano e pili ana i ka makemake o ka glucose i loko o ke koko, a hiki i ka nui o nā lā i kēlā me kēia lā.

ʻO ka hoʻokūkū hui pono e hoʻokō ʻia ma lalo o ka nānā mālama olakino.

Hoʻohana me ka insulin

I kekahi mau hihia, ʻaʻole hiki i ka monotherapy me Glemaz, pū me ka hui pū me ka metformin, ʻaʻole i hāʻawi i ka hopena i makemake ʻia: ʻaʻole hiki ke hoʻokō glycemic control. I kēlā kūlana, hiki i ka hui pū ʻana o ka glimepiride me ka insulin. Ma kēia hihia, ua hoʻomau ke ʻano o ka hoʻopiʻi ʻana o ka glimepiride i ʻōlelo ʻia i ka mea maʻi, a hoʻomaka ka mālama ʻana i ka insulin ma kahi liʻiliʻi he nui, me ka hoʻolōʻihi o ka hoʻonui ʻia ʻana o kona kūlohelohe ma lalo o ka kāʻei o ke kaila o ka glucose koko.

Hoʻohālikelike ka hoʻomaʻamaʻa ʻana i ka lāʻau lapaʻau kauoha paʻa.

Ke hoʻololi nei i kekahi lāʻau lapaʻau hypoglycemic waha i glimepiride

Initial lā i kēlā me kēia lā: 1 mg (ʻoiai ke neʻe ʻia ka mea maʻi i ka glimepiride me ka nui o ka nui o kekahi lāʻau lapaʻau hypoglycemic waha).

Pono ke hoʻonui o ke koena o Glemaz i kahi mahele, e pili ana i ka hopena o ka mālama ʻana, ke ʻano a me ka lōʻihi o ka hana a ka luna hypoglycemic i hoʻohana ʻia.

I kekahi mau hihia, ʻoi aku ka wā e lawe ai i ka lāʻau hypoglycemic me ka hapalua hapalua, he mea pono paha ia no kahi pōkole (i loko o kahi mau lā) e hoʻokuʻu i ka hoʻomaʻamaʻa ʻana i mea e hōʻea ai i kahi hopena hoʻohui e hoʻonui i ka hōʻeha o ka hypoglycemia.

ʻO ka unuhi ʻana mai insulin a glimepiride

I nā hihia kūʻokoʻa loa, i ka wā e hoʻokele ana i ka inika insulin i nā poʻe maʻi me ka diabetes mellitus type 2, aʻo ka hoʻokūkū ʻana i ka maʻi a me ka mālama ʻana i ka hana huna i ka hana o ka pancreatic β-cells, hiki ke hoʻololi i ka insulin me ka glimepiride.

Hana ʻia ka unuhi ma lalo o ka mākaʻikaʻi paʻa o kahi kauka.

Initial dosis: 1 mg i kēlā me kēia lā.

Nā hopena hopena

Hiki i ka hoʻohana ʻana i ka lāʻau lapaʻau ke kumu i nā hopena hope loa:

• Metabolism: ma hope o ka lawe ʻana i ka lāʻau lapaʻau, hiki i ke ʻano o nā hopena hypoglycemic hiki ke loaʻa i kahi pilikia ʻino a ʻano paʻa a ʻaʻole hiki ke kaohi koke ʻia.
• Nā Organs o ka hihiʻo: i ka wā o ka maʻi (ma ka hoʻomaka ʻana), hiki ke nānā ʻia nā mea hoʻolāliʻi e pili ana me nā loli o ke kahe koko.
• Hematopoietic ʻōnaehana: leukopenia, aplastic a hemolytic anemia, i ke hoʻololi ʻana i ka thrombocytopenia koʻikoʻi, pancytopenia, agranulocytosis, erythrocytopenia a granulocytopenia.
• Pūnaehana Digestive: hōʻeuʻeu o ka nausea, ka luaʻi, ka ʻōpū o ka ʻōpū, ʻeha a ʻeha ʻole i ka ʻōpū o ka epigastrium, ka ʻōpū ʻana o ka maʻi, nā māhina o nā huina o nā huakini, jaundice, cholestasis, hepatitis (me ka hoʻomohala ʻana o ka hiki ʻole o ka pepī).
• Hōʻike Allergic: pili ʻili, ʻeha, urticaria i hele mai. ʻO ka maʻamau, ʻōlelo ʻia nā ʻano like ʻole, akā i kekahi manawa hiki iā lākou ke holomua, i hele pū me ka pōkole o ka hanu (a hiki i ke kūkulu ʻana o ka anaphylactic shock), kahi hōʻemi i ke kahe o ke koko. Hiki i kahi hopena cross-allergic me nā derivatives sulfonylurea, sulfonamides a i sulfonamides paha, me ka hoʻomohala ʻana i nā vasculitis allergic.
• Nā kumuhana hou: i kekahi mau hihia, hiki ke hoʻomohala ʻia ka hoʻomanawanui porphyria cutaneus, photosensitivity, hyponatremia, asthenia, a me ke poʻo.

Ka hana lāʻau lapaʻau

ʻO Glemaz kahi lāʻau lapaʻau hypoglycemic oral. ʻO ka mea hana nui o ka lāʻau ka glimepiride, ka mea e hoʻoulu ai i ka mea huna a hoʻokuʻu i ka insulin mai ka pancreatic β-cells (pancreatic effects), hoʻomaikaʻi i ka ʻike ʻana o nā ʻolua peripheral (pūpū a me ka momona) i ka hana a kāna iho i ka insulin (extra-pancreatic effects).

Me kahi inestion hoʻokahi, hoʻihoʻi ka ola i 60% o ka nui i lawe ʻia, ʻo ke koena 40% e hele ma loko o nā ʻōpū. ʻAʻole i ʻike ʻia ka waiwai i hoʻololi ʻia i loko o ka urine. T_1/2 i ka hoʻokaʻawale ʻana o nā wai o ka lāʻau ma ka serum e pili ana i ka regimen doses, he mau manawa 5 - 8 mau hola._1/2 ma hope o ka lawe ʻana i ka lāʻau lapaʻau i nā papa kiʻekiʻe.

Ke keu

Wahi a nā loiloi o Glemaz, ma hope o ka lawe ʻana i nā koina kiʻekiʻe o ka lāʻau, ulu ka hypoglycemia, mau loa 12-72 mau hola, hiki ke hana hou hou ma hope o ka hoʻihoʻi ʻana i nā pae glucose koko maʻamau.

Hōʻike ʻia ka hypoglycemia e: hoʻonui i ka hilo, tachycardia, hopohopo, palpitations, hoʻonui i ke koko, a me ka makemake, ʻeha ka naʻau, ka ʻeha, ka arrhythmia, dizziness, ka hiamoe mau, ka nausea, ka luaʻi, ka hopohopo, kaʻeha, ka hōʻeha, ka hoʻohaʻahaʻa, ka haunaele, , paresis, puʻuwai, hoʻopiʻi, hoʻonaninani loa, coma.

No ka mālamaʻana i kahi overdose, pono ia e hoʻonāukiuki i ka luaʻi i ka mea maʻi. Ua hōʻike pū ʻia ka wai inu momona me ka sodium picosulfate a me ka honi i hana ʻia.

Inā hoʻohana ʻia nā papa ʻai kiʻekiʻe o ka lāʻau lapaʻau, a laila hana ʻia ka lavage gastric, a laila hoʻōla ʻia ka sodium picosulfate a me nā arika i hoʻoili ʻia, ma hope o ka hoʻolilo ʻia o ka dextrose. Hoʻomaʻamaʻa hou ka hoʻomaʻamaʻa hou.

Hoʻopili pū me nā lāʻau ʻē aʻe

Me ka hoʻohana pū ʻana o ka lāʻau lapaʻau me:

• Metformin, insulina, nā moʻolelo hypoglycemic konohiki, allopurinol, ACE nā mea kūpale, kane keka hormones, anabolic steroid, chloramphenicol, cyclophosphamide, coumarin nā mea loaʻa, ifosfamide, trofosfamide, fibrates, fenfluramine, sympatholytic, fluoxetine, Mao nā mea kūpale, pentoxifylline, miconazole, probenecid, phenylbutazone , oxyphenbutazone, azapropazone, salicylates, derivatives quinolone, tetracyclines, sulfinpyrazone, fluconazole, tritokvalin - ola ka lethality o kāna hopena hypoglycemic,
• Acetazolamide, diazoxide, barbiturates, saluretics, glucocorticosteroids, thiazide diuretics, epinephrine, glucagon, acid nikotinic a me nā kumulima, nā derivia phenothiazine, estrogens a me progestogens, heʻano thyroid - ua nawaliwali kona hopena hypoglycemic,
• Kumuhana H₂- nā mea mālama, clonidine, ka waiʻona - hiki iā mākou ke nawaliwali a hoʻonui i ka hopena hypoglycemic,
• I nā lāʻau lapaʻau e pale i ka hematopoiesis pumehana o ka iwi, hoʻonui ʻia ka nui o ka myelosuppression.