Protaphane® HM (Protaphane® HM)

Protafan ® HM Penfill ®

Ka hana lāʻau lapaʻau

Hoʻopili ʻo ia me ka mea kūpaʻa membrane plasma hou a komo i loko o ka pū, kahi e hoʻōla ai i ka phosphorylation o nā protein cellular, hoʻowalewale i ka synthetase glycogen, pyruvate dehydrogenase, hexokinase, pale i ka lipipole a adipose a me lipoprotein lipase. I ka hui pū ʻana me kahi receptor kūikawā, e hoʻomaʻemaʻe i ke komo ʻana o ka glucose i loko o nā cell, hoʻomaikaʻi i kona uptake e nā ʻāpana a hāpai i ka hoʻololi ʻana i ka glycogen. Hoʻonui i nā lako glycogen, hoʻoulu i ka syntept peptide.

Lapaʻau Kauka

Hoʻomohala ka hopena i nā hola 1.5 ma hope o ka hoʻokele sc, hiki i ka lōʻihi ma hope o 4-12 mau hola a kū i nā hola 24. ʻO Protafan NM Penfill no ka maʻi melemele e paulele ana i ka insulin e hoʻohana ʻia me ka insulin basal i hui pū ʻia me nā pōkole hana pōkole, no ka hilinaʻi ʻole i ka insulin - e like me monotherapy , a i hui pū me nā insulins hana wikiwiki.

Hoʻohui

E hoʻonui ʻia ka hopena hypoglycemic e ka acetylsalicylic acid, alkohol, alpha and beta blockers, amphetamine, anabolic steroids, clofibrate, cyclophosphamide, fenfluramine, fluoxetine, ifosfamide, MAO inhibitors, methyldopa, tetracycline, trifamazidine, trifamquidix, trifamaquidiine, trifamquidiine thiazides), glucocorticoids, heparin, contraceptives hormonal, isoniazid, lithium carbonate, nicotinic acid, phenothiazines, sympathomimetics, tricyclic antidepressants.

ʻLoe a me ke kākele

Protafan ® HM Penfill ®

P / c. Kuhi ʻia ka lāʻau no ka hoʻokele subcutaneous. ʻAʻole hiki ke hoʻokomo ʻia ka hoʻokuʻu ʻia o ka insulin i loko.

Koho ʻia ke ʻano o ka lāʻau lapaʻau hoʻokahi, me ka noʻonoʻo ʻana i nā pono o ka mea maʻi. ʻO ka maʻamau, ma waena o 0.3 a me 1 IU / kg / lā. ʻOi paha ka pono o kēlā me kēia lā i ka insulin i ka mea maʻi me ka pale o ka insulin (no ka laʻana, no ka wā ʻōpiopio, a me ka poʻe maʻi me ka huelo), a haʻahaʻa ka poʻe maʻi me ka hoʻomaha o ka hana endogenous insulin.

Hiki ke hoʻohana ʻia ka Protafan ® NM ma ka monotherapy a me ka hoʻohui pū me ka insulin hana wikiwiki a pōkole wale nō.

ʻO ka Protafan ® NM e mālama pinepine ʻia nā subcutaneously i loko o ka ʻūhā. Inā kūpono kēia, a laila hiki ke hana ʻia nā inikini ma ka paia o ka ʻōpū o ke kuʻuna, i loko o ka wahi o gluteal a i ʻole ke ʻano o ka pīhoihoi o ka ʻōhā. Me ka hoʻopuka ʻana o ka lāʻau lapaʻau i loko o ka ʻūhā, aia ke ʻano o ka pānaʻi lohi ma mua o ke komo ʻana i nā wahi ʻē aʻe. Inā hana ʻia ka ʻōlohelohe i loko o kahi pālahalaha o ke kino i hoʻonui ʻia, hiki ke hoʻēmi ʻia ka nui o ka hōʻino o ka lawelawe ʻana i ka maʻi intramuscular o ka lāʻau.

Pono ka noho iki ma lalo o ka ʻili no ka liʻiliʻi o 6 kekona, e hōʻoiaʻiʻo ana i kahi maʻi piha. Pono e hoʻololi mau i ka pūnaewele injection i loko o ke kahawai anatomical i mea e pale ai i ka hoʻomohala ʻana o ka lipodystrophy.

Hoʻohana ʻia nā Protafan ® NM Penfill ® no ka hoʻohana ʻana me nā ʻōnaehana inikua o Novo Nordisk a me nā pono ponoʻī o NovoFine ® a i ʻole nā ​​manamana NovoTvist ®. Pono e nānā ʻia nā ʻōlelo kikoʻī no ka hoʻohana a me ka hoʻokele ʻana o ka lāʻau lapaʻau.

ʻO nā maʻi e like me ka maʻi hopohopo a hele pū ʻia me ke kuni, e hoʻonui pinepine i ke kino o ka maʻi o ka insulin. Hiki ke koi ʻia ka hoʻoponopono ʻana inā he maʻi nā mea maʻi i nā maʻi, nā ate, ka hana adrenal function, pituitary a i ʻole thyroid gland. Hiki pū paha ke pono no ka hoʻoponopono hoʻoponopono ʻana i ka wā e hoʻololi ai i ka hana kino a i ka ʻai maʻamau o ka mea maʻi. Hiki ke koi ʻia ka hoʻoponopono ʻana i ka neʻe ʻana i ka mea maʻi mai kahi ʻano like ʻole o ka insulin i kekahi

Ke keu

Nā Hoʻomaka ka hoʻomohala ʻana o ka hypoglycemia (kaomi anuʻo, palpitations, nā nui, ka pōloli, ka ʻōpū, ka huhū, ka palaka, ka ʻeha, ka luhiluhi, ka nele o ka neʻe, ka ʻōlelo a me ka nānā ʻana i ka ʻike, ʻeha). Hiki i ka hypoglycemia koʻikoʻi ke alakaʻi i ka pohō ʻole a paʻa ʻole i ka hana o ka lolo, ka coma, a me ka make.

Lāʻau: ka momona gula a i ʻole ka momona (inā ʻike ka mea maʻi), s / c, i / m a i ʻole iv - glucagon a i ʻole iv - glucose.

E hoʻokuʻu i ke ʻano

Hoʻopaʻa no ka hoʻokele subutaneus, 100 IU / ml (mau kīʻaha). I loko o nā pahu o nā aniani o ka papa hydrolytic 1, i hoʻopili ʻia me nā mea ʻoki mai ka brAVEutyl / polyisoprene kalo a me nā pahu aila, 10 ml kēlā me kēia, i loko o ka pā i ka pahu hopu 1 fl.

Hoʻopaʻa no ka hoʻokele subcutaneous, 100 IU / ml (cartridges). Ma 3 ml Penfill ® mau pahu pahu aniani, 5 mau pahu pahu i loko o nā kekeke, 1 mau bele i loko o kahi pā kāleka.