Pehea e hoʻohana ai i ka lāʻau lapaʻau Lisinopril Teva?

- ka momona o ka arterial (ma ka monotherapy a i hui pū ʻia me nā lāʻau antihypertensive),

- ka huhū puʻuwai kūpilikiʻi (ma ke ʻano he hui hoʻohui)

- ka mālama mua ʻana i ka maʻi myocardial akene (i nā hola 24 mua me ka hemodynamics paʻa e mālama i kēia mau ʻōuli a pale i nā hana neʻe o ka ventricular a me ka nele o ka naʻau),

- nephropathy diabetic (hoʻohaʻahaʻa i ka albuminuria i nā mea maʻi me ka maʻi diabetes mellitus type 1 me ke kaʻe koko maʻamau, a me nā mea maʻi me ka maʻi diabetes mellitus type 2 me ke arterial hypertension).

Nā Hoʻohui

- Hypersensitivity i ka lisinopril, nā ʻāpana ʻē aʻe o ka lāʻau a i ʻole nā mea ʻē aʻe o ACE,

- ka mōʻaukala o ka angioedema (me ka hoʻohana ʻana o nā mea ʻē aʻe o ka ACE),

- he hoʻohelehe Quincke edema a / a i ʻole angioedema idiopathic,

- makahiki a hiki i ka 18 makahiki (ʻaʻole i hoʻokū ʻia ka hana a me ka palekana),

- Ka hāpai a me ka manawa o ka umauma.

Nā mālamaheʻi: ʻo ka stenosis renalal renal stenosis a i ʻole ka stenosis o ke aʻalopona pālua me ka azotemia holomua, ke ʻano ma hope o ka hoʻololi ʻana i ka huehue, ka pilikia ʻole, hemodialysis e hoʻohana ana i nā membranes dialysis nui (AN69R), azotemia, hyperkalemia, stenosis o ka aortic orifice, hypertrophic obstructive cardiomyelopic primary, hypotension, cerebrovascular disease (me ka cerebrovascular insufficiency), maʻi ʻōpū coronary, kahakaha coronary, maʻi autoimmune hono konohū (me ka scleroderma, systemic lupus erythematosus), inhibition of bone marum hematopoiesis, nā kūlana i hui pū ʻia me ka hoʻēmi ʻana i ka nui o ke koko (BCC) (me ke ʻano o ka maʻi o ka maʻi, ka luaʻi), e hoʻohana i nā mea maʻi ma ka mea ʻai hoʻokaʻawale. papa paʻakai, i nā mea maʻi ʻelemakule, hoʻohana pinepine ʻia me nā hoʻomākaukau pālolo, diuretics, nā lāʻau ʻauhau antihypertensive, nā NSAID, ka hoʻomākaukau ʻana lithium, antacids, colestyramine, ethanol, insulin, me ka hoʻomākaukau ʻana o ka hypoglycemic hoʻomākaukau Tami, allopurinol, procainamide, gula hoomakaukau, antipsychotics, tricyclic antidepressants, barbiturates, Hoʻokolohua-blockers, kalipuna Kanal blockers lohi.

Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana

ʻO ka lāʻau Lisinopril-Teva lawe ʻia i ka manawa 1 i ka lā / iʻa, ʻaʻole o ka manawa ʻaina, ʻoi aku ka manawa like ʻole o ka lā. Kahi ʻia ke ʻano o ka ʻāʻī. Me ka hypertension arterial, ʻaʻole i loaʻa nā mea maʻi i nā lāʻau antihypertensive e hoʻohana i ka 5 mg / lā. I ka nele o kahi hopena therapeutic, hoʻonui ʻia ke kahe i kēlā me kēia 2-3 mau lā ma ka 5 mg i kahi dosis o 20-40 mg / lā (e hoʻonui ana i ka nui ma mua o 40 mg / lā maʻamau ʻaʻole alakaʻi i ka emi o ke kahe koko).

ʻO ka awelika mālama mālama pono o kēlā me kēia lā he 20 mg. ʻO ka pae ʻauʻau nui loa ʻo kēlā me kēia lā he 40 mg. Hoʻokomo pinepine ka hopena therapeutic ma hope o 2-4 mau pule mai ka hoʻomaka ʻana o ka hoʻomaʻamaʻa, pono ia e noʻonoʻo i ka wā e hoʻonui ai i ka ʻano lāʻau. Me ka hopena ʻole, hiki i ka hoʻohana pinepine ʻana i ka lāʻau me nā lāʻau antihypertensive ʻē aʻe.

Inā loaʻa i ka mea maʻi ka hoʻomaʻamaila mua me ka diuretics, a laila pono e hoʻokaʻawale ke kau i ka lāʻau lapaʻau i nā lā 2-3 ma mua o ka hoʻomaka ʻana o ka hoʻohana ʻana i ka lāʻau Lisinopril-Teva. Inā ʻaʻole hiki ʻole kēia, a laila ʻaʻole pono ka nui o ka hopena mua o Lisinopril-Teva ma mua o 5 mg / lā. Ma kēia hihia, ma hope o ka lawe ʻana i ka ʻai mua, ʻōlelo ʻia ke nānā ʻana i nā hola he nui (ʻo ka hopena ʻoi loa ka hopena ma hope o ka 6 mau hola), ʻoiai e loaʻa ana kahi hōʻailona o ka neʻe koko.

Ka hana lāʻau lapaʻau

ʻO ka pale o ACE, e hōʻemi i ka hoʻokumu ʻana o ka angiotensin II mai angiotensin I. ʻO kahi hoʻoneʻe i loko o nā kiko o ka angiotensin II e alakaʻi ana i kahi emi o ka hoʻokuʻu ʻana o ka aldosterone. Hoʻemi i ka hōʻemi o ka bradykinin a hoʻonui i ke ʻano o ka prostaglandins. Hoʻemi i ka huakaʻi pale kime peripheral (OPSS), ke koko, ka preload, ke kaomi ʻana i nā pulillary pulmonary, e hoʻonui ai i ka nui o ke koko ka nui a me ka hoʻonui ʻana i ka hoʻokaʻawale Myocardial i loko o nā mea maʻi me ka hoʻopiʻi o ka naʻau maʻi. E hoʻonui i nā arela i ka ʻoi aku ka nui ma mua o nā veins. Hoʻokomo ʻia kekahi mau hopena i ka hōʻike ʻana i ka ʻōnaehana renin-angiotensin-aldosterone (RAAS). Me ka hoʻohana ʻana i ka lōʻihi, ua emi nā hypertrophy o ka myocardium a me nā paia o nā ʻāpana o ke ʻano o ka mea pale. Hoʻomaikaʻi i ka hāʻawi ʻana i ke koko i ka myocardium ischemic.

Hoʻopau ka Lisinopril i ka albuminuria. ʻAʻole pili i ka luhi o ke kaila koko i loko o nā poʻe maʻi me ka maʻi mellitus a ʻaʻole i alakaʻi i ka hoʻonui ʻana i nā hihia o ka hypoglycemia.

Nā hopena hopena

Mai ka ʻōnaehana cardiovascular: pinepine - he mau hōʻailona i hōʻemi i ke koko, a me ka hypotension orthostatic, pinepine - e haʻi ʻia ka maʻi myocardial, tachycardia, palpitations, ʻohiʻoni a Raynaud, ʻāleka - bradycardia, tachycardia, hōʻemi i nā hōʻailona o ka hoʻopiʻi o ka puʻuwai o ka naʻau, ʻeha o ka hōʻuluʻulu ʻana me ka ʻeha o ka ʻōpū.

Mai ka pūnaehana nūnaehana kikowaena: pinepine - dizziness, headache, infrequently - mood lability, paresthesia, sleep disturb, stroke, jarang - confingment, asthenic syndrome, convulsive twitching of the muscle of the limb and lips, drowsiness.

Ma ka ʻāpana o ka ʻōnaehana hematopoietic a me ka ʻōnaehana lymphatic: lohi - ka hoʻemi ʻana i ka hemoglobin, hematocrit, ʻehā loa - leukopenia, neutropenia, agranulocytosis, thrombocytenia, eosinophilia, erythropenia, hemolytic anemia, lymphadenopathy, autoimmune bone, inhibition.

Nā ʻōlelo kikoʻī

ʻO ka pinepine, ʻo ka hoʻohaʻahaʻa pane ʻana i ke kahe o ke koko e loaʻa me ka hoʻohaʻahaʻa i ka BCC i hoʻoulu ʻia e ka diuretic therapy, kahi hoʻohaʻahaʻa i ka sodium chloride i ka meaʻai, ka dialysis, ʻōpū, a me ka luaʻi. Ma lalo o ka mākaʻi o kahi kauka, noi ʻia e hoʻohana i ka lāʻau Lisinopril-Teva i nā mea maʻi me ka maʻi ʻalihi coronary, kaʻi ʻana o cerebrovascular, ma kēlā me ke kao nui o ke kahe koko hiki ke alakaʻi i ka myocardial infarction a i ʻole hōʻeha. ʻO ka hoʻohana ʻana i ka lāʻau Lisinopril-Teva hiki iā ia ke alakaʻi i ka hana o ka papalā i kahi hana ʻole, a me ka hoʻomaʻamaʻa ʻole ʻana i ka maʻi, ka mea maʻamau aʻaʻole hoʻi e hōʻemi ʻia ma hope o ka hoʻokuʻu ʻana o ka lāʻau. ʻO ka hypotension arential ka mea ʻaʻole he contraindication no ka hoʻohana hou ʻana i ka lāʻau.

Ma ka hihia o ka stenosis o ka aralula renal (ʻoi aku me ka bilateral stenosis a i ʻole ka hiki ʻana o ka stenosis o ke kino o hoʻokahi oiwi), a me ka pelalone o ka holo ʻana o ke kai i kumu ʻia e ka hyponatremia a me hypovolemia, ka hoʻohana ʻana i ka lāʻau Lisinopril-Teva hiki ke alakaʻi i ka hana ʻole ʻana i ka hopena, a me ka hana ʻole ʻana o ka maʻi kaulike. maʻamau pinepine ʻole o ka hōʻea ʻana ma hope o ka hoʻokuʻu ʻana o ka lāʻau.

Hoʻohui

Me ka makaʻala, pono ka hoʻohana ʻana i ka lisinopril me ka diuretics potassium-sparing (spironolactone, triamteren, amiloride, eplerenone), hoʻomākaukau pākaha, nā mea paʻakai e loaʻa ana i ka pālolo, cyclosporine - hoʻonui ʻia ka hopena o ka hyperkalemia, ʻoi aku hoʻi me ka hana renal impaired. No laila, pono e hoʻohui pono ʻia kēia mau hui i ka hoʻoholo ʻana o kahi kauka ponoʻī me ka nānā pinepine ʻana i ka serum potassium a me ka hana ʻana o ka maʻi. Me ka hoʻohana like pū me nā diuretics a me nā mea pono antihypertensive, e hoʻonui ai i ka hopena antihypertensive o ka lisinopril.

Me ka hoʻohana like pū me nā NSAIDs (e komo pū ana me ka cyclooxygenase-2 (COX-2) inhibitors), ka waikawa acetylsalicylic i kahi pākaʻi ma mua o 3 g / lā, estrogens, a me nā puʻuwaiʻonikekikini, e hoʻemi ʻia ka hopena antihypertensive o lisinopril. Nā NSAID, e komo pū ai me COX-2, a me ACE inhibitors hoʻonui i ka serum potassium a hiki ke hoʻōki i ka hana renal. Hoʻololi hou kēia hopena. Hoʻololi ʻo Lisinopril i ka hoʻopiʻi ʻana o ka mākaukau lithium, no laila, me ka hoʻohana like ʻana, he hoʻolōʻihi i ka hoʻolilo ʻia o kona kao ʻana i ka plasma koko, e hiki ai ke hoʻonui i nā hanana o nā hanana ʻino, no laila, ka mālama pono ʻana o ka lithium ma ka serum.

Me ka hoʻohana like ʻana me nā antacids a me colestyramine, ke hoʻemi ʻia nei o ka lisinopril mai ka gastrointestinal tract.

Nā nīnau, nā pane, nā loiloi e pili ana i ka lāʻau Lisinopril-Teva

ʻO ka ʻikepili i hāʻawi ʻia e hana no nā lāʻau lapaʻau a me nā lāʻau lapaʻau. Aia nā ʻike e pili ana i ka lāʻau lapaʻau e pili ana i nā ʻōlelo i hoʻopili ʻia e ka mea hoʻopiʻi e ka mea hana. ʻAʻohe ʻikepili i hoʻopili ʻia ma kēia a ʻole kekahi ʻaoʻao o ka pūnaewele a mākou e hiki ke lawelawe ma kahi kūʻokoʻa no ka hoʻopiʻi pilikino i ka loea.

I ka manawa hea e lawe ʻia ai ka lāʻau lapaʻau me ka mālama?

E like me ke kānāwai, mālama ʻia ka "Lisinopril Teva" i hōʻike ʻia i loko o nā hihia penei:

ʻO ka hōʻeha o ka lua o ka pilikia me ka bilateral renal stenosis stenosis me ka azotemia holomua a me ke kūpaʻa ʻana o kahi kūlana ma hope o ka hoʻololi ʻana o kēia kino.
Me ka hyperkalemia, stenosis o ka waha o ka aorta, hypomyrophic obstract cardiomyopathy.
E kūʻē i ke kūmole o ka hyperaldosteronism maʻamau, hypotension arterial a me nā maʻi cerebrovascular (komo me ka hala o ke kaʻe o ka lolo).
I ka loaʻaʻana o ka maʻi naʻau coronary, ka pilikia coronary, nā maʻi ʻōnaehana o ka autoimmune o nā ʻili hoʻohui (me ka scleroderma, ka systemic lupus erythematosus).
I ka hihia o ka paʻa ʻana o ka hematopoiesis pumehana o ka iwi.
Me kaʻai ʻai i ka paʻakai.
E pale aku i ke kua o ke ʻano o ka maʻi hypovolemic ma muli o ka hopena o ka maʻi a i ʻole ka luaʻi.
Ona elemakule.

Nā ʻōkuhi no ka hoʻohana

Hoʻohana pinepine nā papa ʻo "Lisinopril Teva" i hoʻokahi lā i ke kakahiaka, i ke kakahiaka, me ka manaʻo o ka ʻai ʻana o ka meaʻai, ʻoi aku ka manawa like. Ma ka heleʻana o ka maʻi arterial hypertension, nā mea maʻi i loaʻa ʻole i nā lāʻau antihypertensive e kuhikuhi i nā milligrams 5 i hoʻokahi lā. Inā ʻaʻohe kumu, e piʻi ka dosage i kēlā me kēia lā ʻekolu o nā 5 milligrams i kahi maʻamau therapeutic maʻamau o 40 milligrams (ʻoi aku ka nui o kēia kuʻina o ka maʻamau ʻaʻole maʻamau e alakaʻi i kahi kao mau i ke kaomi). ʻO ka hāmeʻa kākoʻo maʻamau o ka lāʻau i ka 20 milligrams.

ʻO ka hopena piha, ma ke ʻano he kānāwai, hoʻomohala ma hope o ʻehā mau pule mai ka hoʻomaka ʻana o ka lāʻau, pono e noʻonoʻo ʻia i ka wā e hoʻonui ai i ka nui o ka lāʻau lapaʻau. E kū'ē i ke kua o ka hopena o ka hopena lapaʻau, hiki i ka hui pū ʻana me kēia lāʻau lapaʻau me nā lāʻau lapaʻau antihypertensive. Inā ua lawe mua ka mea maʻi i ka diuretics ma mua, a laila he mea nui kā lākou hoʻohana e pani i nā lā ʻekolu i mua o ka hoʻomaka ʻana o ka hoʻohana ʻana iā "Lisinopril Teva." Inā ʻaʻole hiki ʻole kēia, a laila ʻaʻole pono ka nui o ka dosis ma mua o 5 mau milligram i kēlā me kēia lā. Ma hope o ka ʻōlelo mua, pono ia e mālama i ke nānā olakino no kekahi mau hola (ka hopena ʻoi loa ka hopena ma hope o ka hapalua lā), no ka mea, hiki ke mālama ʻia kahi hōʻemi paneʻawa ʻia.

Ma ke alo o ka renovascular hypertension a i ʻole nā kūlana ʻē aʻe me ka hana nui o ka ʻōnaehana renin-aldosterone, ua hāmama ʻia hoʻi e kuhikuhi i kahi mea liʻiliʻi ma mua o 5 milligrams ma lalo o ka hoʻomohala ʻia o ke kauka. Pono ka hoʻoholo o ka mālama ʻana i ka lāʻau lapaʻau ma muli o ka dinamics o ke kahe.

E kū'ē i ke kiʻi o ka hypertension hoʻomau, mālama ʻia ka lāʻau mālama mālama lōʻihi i ka 15 milligrams o ka lāʻau i ka lā. I ka hopena o ka puʻuwai ulu, ua inu mua lākou i ka 2.5 me kahi hoʻonui e ulu iki ma hope o nā lā ʻelima i 5 a i ʻole 10 milligrams. ʻO 20 ka nui ka nui o ke kaila he 20 milligrams.

Ma ka hua myocardial infarction (ma ke ʻano o ka hui pū ʻana), ʻona nā 5 milligram i ka lā mua, a laila ʻoi aku ka nui ma hope o ka iwakāluakūmāhā mau hola a 10 ma hope o ʻelua lā. A laila e lawe i ka 10 milligrams i hoʻokahi lā. ʻO ka papa o ka lapaʻau ʻia ma kahi o ʻeono mau pule. Ma ke ʻano o ka emi ʻana o ke kaohi, ke hoʻōla ʻana me ka lāʻau lapaʻau e nīnau ʻia.

E kūʻē i ke kūleʻa o nephropathy i nā maʻi me nā maʻi maʻi type 2, hoʻohana ʻia nā milligram 10 i hoʻokahi lā i ka lā. Inā kūpono, hiki ke hoʻonui ʻia ka pākiha ina 20 i mea e hoʻokō ai i ka waiwai diastolic pressure ma lalo o ke anuanu 75 o ka mercury i kahi noho. No ka poʻe maʻi me ka maʻi diabetes type 1, like ka nui o nā lāʻau lapaʻau.

Ke keu

ʻO nā hōʻailona o kahi overdose kahi hua i hoʻohaʻahaʻa i ka neʻe ʻana me ka maloʻo o ka mucosa waha, ka wai pākē a me ka wai hoʻoneʻe, hoʻonui i ka hanu a me ka tachycardia. Hoʻomaopopo ʻia kēia ma nā ʻōkuhi no ka hoʻohana a me nā loiloi. "Lisinopril Teva" hiki i ka manaʻo o ka palpitations i hui pū me ka bradycardia, haunaele, hopohopo, huhū, ka hiamoe, ka uritation, mālama, urupapa, hina.

E koi ʻia ka mālama ʻana i ke ʻano o ka gastage lavage, ka hoʻohana ʻana o nā enterosorbents a me nā laxatives. Hōʻike ʻia ka sodium chloride intravenous. Pono ke kaohi o ke kaomi a me ke kaulike electrolyte. E lilo a hemodialysis.

ʻO ke kumukūʻai o kēia lāʻau lapaʻau ma kahi hapa o 10 mg mau nei ma kahi o 116 mau rubles. Aia ia i ka pae a me ka ʻoihana kūʻai.

ʻO ka hui ʻana o "Lisinopril Teva"

ʻO nā mea hoʻohālikelike o ka lāʻau lapaʻau i nīnau ʻia ai ʻo Diroton, Irumed, a me Lysinoton. He mea nui ia e hoʻomaopopo he kākau wale nō kauka kauka lāʻau i nā lāʻau ʻē aʻe ma mua o ka mea i hōʻike ʻia e mākou.

I loko o kā lākou ʻōlelo, ʻōlelo ka poʻe "Lisinopril Teva" he hopena maikaʻi loa no ka hypertension. Ua hoʻomaopopo ʻia he kūpono ia no ka monotherapy, a me ka hoʻohui pū ʻana me nā lāʻau lapaʻau antihypertensive ʻē aʻe.

Hoʻopili i nā mea hoʻohālikelike i ke koko kiʻekiʻe, kōkua ka lāʻau lapaʻau i nā mea maʻi me ka puʻuwai o ka puʻuwai, a ma ke ʻano o ka hoʻomaʻamaʻa mua ʻana o ka hōʻeha puʻuwai naʻau.

Ma nā loiloi o "Lisinopril Teva" loaʻa nā hoʻopiʻi i ka hopena o ka hopena ma ke ʻano o ka hoʻoulu ʻana nui a me ka hōʻike ʻana i nā rashes ma ka ʻili. Akā inā ʻaʻole, makemake ʻia kēia lāʻau lapaʻau e nā mea kūʻai aku no ka pono a me ka uku kumukūʻai.

Pākuʻi helu

5 mg, 10 mg, 20 mg papa

Aia ma ka papa papa

ʻo ka mea hana lisinopril dihydrate 5.44 mg, 10.89 mg a 21.78 mg, like me ka lisinopril anhydrous 5 mg, 10 mg, 20 mg,

nā mea waiwai: mannitol, calcium hydrogen phosphate dihydrate, pregelatinized starch, dye PB-24823, sodium croscarmellose, magnesium stearate.

Ke keʻokeʻo nā papa papa, puni, biconvex, me kahi kakana ma kekahi ʻaoʻao (no ke ʻano o ka nui 5 mg).

He kukui polū nā papa i ka waihoʻoluʻu, hoʻopuni, biconvex, me ka loaʻa ma ka ʻaoʻao (no ke ʻano o ka 10 mg).

He uliuli nā papa papa, hoʻopuni, biconvex me kahi kīʻaha ma kekahi ʻaoʻao (no ke ʻano o 20 mg).

ʻO nā waiwai Pharmacological

Loaʻa ka lōʻihi loa o ka plasma koko i kahi mau hola 7 ma hope o ka lawelawe waha. ʻAʻole ʻai i ka ʻai i ka helu o ka lawe ʻana o ka lisinopril. ʻAʻole paʻa ka Lisinopril i ka protein plasma. Hoʻopili ʻia nā kinipona biologically hoʻonaninani a hoʻololi ʻole ʻia ma o nā keiki. ʻO ka hapalua ola maikaʻi ʻo 12.6 hola. Hoʻopau ʻo Lisinopril i ka pleka.

ʻO Lisinopril-Teva kahi mea pale i ka angiotensin-hoʻohuli pūpuna (ACE inhibitor). ʻO ke kaohi ʻana o ka ACE e alakaʻi i kahi hōʻemi i ka neʻe ʻana o ka angiotensin II (me kahi hopena vasoconstrictor) a i kahi e hoʻoneʻeneʻe nei i ka mea huna o ka aldosterone. Lisinopril-Teva pani hoʻi i ka ʻohi ʻana o ka bradykinin, kahi peptide vasodepressor pāheʻe.A ʻo kahi hopena, ke hoʻemi nei ia i ke kahe o ke koko, i ke kūpaʻa o ka vascular peripheral, pre-a ma hope o ka puʻuwai, hoʻonui i ka nui o ka minuke, ka hopena o ka cardiac a hoʻonui i ka hoʻolilo i myocardial e hoʻopiʻi a hoʻonui i ka hoʻokahe koko i ka ischemic myocardium. I ka poʻe maʻi me ka maʻi myocardial infarction, Lisinopril-Teva, me nitrates, e hōʻemi ana i ka hoʻokumu ʻana o ka maʻi ventricular hema a i ʻole ke kani ʻana i ka naʻau.

- ka huhū puʻuwai ulu (ma ke ʻano o ka paʻakikī paʻakikī me ka diuretics a me nā glycosides cardiac)

- ka maʻi infococose myocardial i loko o nā mea maʻi me ka hemodynamics paʻa me nā hōʻailona ʻole o ka renal dysfunction.

ʻLoe a me ke kākele

Hoʻomaka ka lāʻau lapaʻau me 5 mg i kēlā me kēia lā i ke kakahiaka. Pono e kau ʻia ka paʻu i kahi ala e hāʻawi ai i ka kaohi o ke kahe koko. ʻO ka manawa manawa ma waena o ka hoʻonui ʻana i waena e neʻe ma lalo o 3 mau pule. ʻO ka dosis mālama mālama maʻamau he 10-20 mg o lisinopril 1 ka manawa i kēlā me kēia lā, a ʻo ka nui lahilahi o ka nui o kēlā me kēia lā he 40 mg 1 manawa i kēlā me kēia lā.

Lisinopril-Teva i kuhikuhi ʻia i ka hoʻohui ʻia me ka maʻi paʻa me nā diuretics a me nā digitalis. ʻO ka inamua hoʻomaka he 2.5 mg i ke kakahiaka. Pono e hoʻopaʻa ʻia ka mālama mālama ʻia i nā hana me nā piʻi o 2.5 mg me kahi manawa o nā hebedoma 2-4. ʻO ka papa mālama mālama maʻamau ʻo 5-20 mg hoʻokahi i kēlā me kēia lā. Mai ʻoi aku i kahi kiʻekiʻe loa o 35 mg o lisinopril / lā.

Acar myocardial infarction i nā mea maʻi me ka hemodynamics paʻa.

Hiki i ka mālama ʻana me ka lisinopril-Teva ke hoʻomaka i loko o 24 mau hola ma hope o ka hoʻomaka ʻana o nā hōʻailona, hoʻolako ʻia ka hemodynamics mau (ʻoi ke koko hoʻonaninani a ʻoi aku ma mua o 100 mmHg, ʻaʻohe hōʻailona o ka hakahaka renalop), a me nā mea maʻamau no ka hōʻeha ʻana i ka puʻuwai (thrombolytic agents, acetylsalicylic acid, beta-blockers, nitrate). ʻO ka maʻa mua he 5 mg, ma hope o 24 mau hola - kahi hou 5 mg, ma hope o 48 mau hola - 10 mg. A laila aia ka paila he 10 mg o lisinopril 1 manawa i ka lā.

ʻO nā mea maʻi me ka hoʻohaʻahaʻa koko systolic haʻahaʻa (≤ 120 mm Hg) ma mua o ka mālama ʻana a i ka wā 3 mau lā mua ma hope o ka hōʻeha ʻana o ka naʻau e loaʻa i kahi haʻahaʻa therapeutic haʻahaʻa o 2.5 mg o Lisinopril-Teva no ka mālama ʻana. Inā emi ke ʻano o ka systolic ma mua o 90 mm Hg. ʻAniā. ʻoi aku paha ma mua o ka hola 1 e haʻalele ʻia lisinopril-Teva.

E hoʻomau ʻia ka hoʻomanawanui ʻana no nā hebedoma 6. ʻO ka palena liʻiliʻi ma 5 mg no ka lā. ʻO nā maʻi me nā maʻi o ka puʻuwai puʻu e hoʻomau e mālama ʻia me ka lisinopril-Teva. Hiki ke hāʻawi ʻia ka lāʻau lapaʻa i ka manawa like me ka nitroglycerin (intravenously a i ʻole i ke ʻano o kahi mea ʻili kino).

Inā loaʻa i ka infarction myocardial, hāʻawi ka lisinopril i ka hoʻohui i ka maʻamau maʻamau maʻamau (a me nā ʻoihana thrombolytic, acetylsalicylic acid, beta-blockers), maikaʻi me ka nitrates.

I nā poʻe maʻi kahiko, pono ke hoʻoponopono ʻia ka ʻaha ʻana ma ke ʻano o ka pae o ka hana (no ka nānā ʻana i ka hana o ka pūpū), kahi i helu ʻia ai e ka ʻano ʻo Cockroft:

(140 - makahiki) × ke kaumaha o ke kino (kg)

0.814 × serum creatinine concentrations (μmol / L)

(No nā wahine, pono e hoʻonui ʻia ka hopena i loaʻa i kēia ʻatikala e 0.85).

Nā maʻi i loko o nā mea maʻi me ka hana renal i palena iki ʻia (ka cleinine clearance 30 - 70 ml / min):

ʻO ka dosis mua ka 2.5 mg ma ke kakahiaka, ʻo ka mālama mālama ʻia he 5-10 mg i ka lā. Mai oi aku i kahi kiʻekiʻe loa o 20 mg o lisinopril i kēlā me kēia lā.

Hiki ke lawe ʻia ka Lisinopril-Teva me nā manaʻo ʻole o nā meaʻai, akā me ka wai o ka wai lawa, ʻo ka manawa 1 ka lā i kēlā me kēia lā, ʻoi aku ka maikaʻi i ka manawa like.

Hoʻopili i nā lāʻau lapaʻau

Me ka hoʻohana like ʻana o nā papa Lisinopril-Teva a:

- hiki ke hoʻemi ʻia ka lithium ma ka lithium excretion mai ke kino, no laila, pono e nānā pono i ka nānāʻana o ka lithium i loko o ka serum koko.

- analgesics, non-steroidal anti-inflammatory drug (no ka laʻana, ka acetylsalicylic acid, indomethacin) - hiki ke hoʻonāwaliwali i ka hopena hypotensive o lisinopril

- baclofen - hiki iā ia ke hoʻoikaika i ka hopena hypotensive o ka lisinopril-diuretics - hiki ke hoʻonui i ka hopena hypotensive o ka lisinopril

- ka diuretics pākoki-sparing (spironolactone, triamteren a amiloride) a me nā mea hoʻomohala potassium e hoʻonui i ka hopena o ka hyperkalemia

- nā lāʻau antihypertensive - hiki iā ia ke hoʻonui i ka hopena hypotensive o lisinopril

- ka mea hoʻohālikelike, nā lāʻau lapaʻau, nā wahi hiamoe - he nui paha ka hopena o ke kahe koko

- allopurinol, cytostatics, immunosuppressants, cicicosteroids systemic, procainamide - ka hopena o ka hoʻomohala ʻana i ka leukopenia e hoʻonui

- nā kinemona antidiabetic waha (derony o ka sulfonylurea, biguanides) a me ka insulin - hiki ke hoʻonui i ka hopena hypotensive, ʻoi aku hoʻi i nā hebedoma mua o ka hui hui ʻana.

- amifostine - hiki ke hoʻonui ʻia ka hopena hypotensive

- antacids - i emi ka bioavailability o lisinopril

- sympathomimetics - hiki ke hoʻonui ʻia ka hopena hypotensive

- inu wai - ulu paha i hopena o ka inu wai

- sodium chloride - nāwaliwali o ka hopena hypotensive lisinopril a me nā hiʻohiʻona o nā hōʻailona o ka hana puʻuwai.

E hoʻokuʻu i ke ʻano

ʻO ka lāʻau lapaʻau ma ke ʻano o nā papa. ʻO ka nānā ʻole o ka hoihoi, ʻike lākou i ka ʻano o ka bvalvex a me ka pena keʻokeʻo. Aia ka pilikia ma kekahi ʻaoʻao o nā pā, ma ka ʻaoʻao ʻē ke kahakaha "LSN2.5 (5, 10, 20)".

Aia nā hiʻohiʻona o ka hoʻokō i ka hilinaʻi ʻana o ka waiwai ikaika i loko o ka lāʻau lapaʻau. ʻO ke kumu o kēia ʻano, ua hoʻokomo ʻia nā papa i loko o kahi pūʻulu blister o 10 mau ʻāpana. I kahi pākaha o 2.5 mg, 3 mau pahu like i kau ʻia i loko o hoʻokahi pākeke, 5 mg - 1 a i ʻole 3 mau ʻāpana. Hoʻololi ʻia nā paila he 10 a 20 mg ma 1, 2 a i ʻole 3 blisters ma kēlā me kēia pā.

Nā hana lāʻau

Lisinopril pale i ka angiotensin-hoʻololi lela, ʻo ia kahi mika no ka kaohi ʻana o ka angiotensin I i ka angiotensin II. A ʻo kahi hopena, ua hoʻemi ʻia ka synthesis aldosterone a me ke kū'ē o ke vipular peripheral, a hoʻonui ʻia ka hana prostaglandin. Hōʻemi kēia hopena i ka emi ʻana o ke koko, ke kaomi ʻana i nā capillary pulmonary a me ka preload, he hoʻonui i ke kahe o ke kahe koko.

Mālama i ka lāʻau lapaʻau e hoʻomaikaʻi i ka hāʻawi ʻana i ke koko i ka ischemic heart muscle. Hiki i ke hōʻola lōʻihi ke hoʻemi i ka myocardial hypertrophy. I ka poʻe maʻi me ka puʻuwai naʻau maʻi, e piʻi nui ka manaʻolana. Inā he hōʻeha ʻeha o ka puʻuwai, akā ʻaʻole i hōʻike ʻia ka puʻuwai naʻau o ka maʻi, a laila me ka hoʻohana ʻana i ka lāʻau lapaʻau, haʻalele nui ka maʻi ventricular a me ka wikiwiki.

I nā lā mua o ka lāʻau lapaʻau, ʻike ʻia ka hopena hypotensive o ka lāʻau. Aia a hōʻea i loko o 1-2 mau mahina o ka hoʻokomo mau ʻana i ka lāʻau.

Pono e hali ʻia ma ka noʻonoʻo kekahi mau ala i hiki ke hoʻopilikia i ka waiwai o ka pharmacokinetic o ka lāʻau lapaʻau.

hōʻemi i ka hoʻomaʻemaʻe, ke kīwī a me ka bioavailability (16%) i ke alo o ka hina ʻole o ka naʻau,
mahuahua i nā manawa paʻa o ka lisinopril ma ka plasma me ka hana ʻole ʻole;
2 mau manawa i ka neʻe ʻana o ka plasma i loko o nā ʻelemakule,
ʻO 30% ka emi ʻana o ka bioavailability a me nā kāpena 50% e kū'ē i ka cirrhosis.

Nā hopena hopena, overdose

ʻO ka hopena ʻino ke wā e lawe ai iā Lisinopril-Teva i mau ʻāpana e like me ke alapine i ka hōʻike. I ka pinepine aʻe, ʻo ke ʻano maʻi kēia alakaʻi i nā hopena i lalo:

orthostatic hypotension,
haʻi ʻia ʻana
ʻeha, poʻomana,
huhū
utuka
nā ninia
lawelawe inoa ʻole.

Pono ke koho o ka dosage e kekahi loea. Ma ka hihia o kahi i koho ʻia ʻole a i ʻole ʻoi aku ka nui o ka paipai i hōʻike ʻia, hiki i kekahi helu o nā ʻaoʻao.

ʻO ka maʻamau, hōʻike ʻia kahi overdose e kēia mau hōʻailona:

hina hāʻule nui
ka malo maloʻo
waie ʻole wai-electrolyte,
pilikia kūlohelohe
wikiwiki hanu
palpitations
āhāhuʻe
hopohopo
hoʻonui ulu irritability
hiamoe
brieociaia
huhū
mālama urinary
constipation
pākaukau o ka māmā.

ʻAʻohe mea antidote kikoʻai no ka mālama ʻana i ka overdose. Pono e holoi i ka ʻōpū, e hōʻoia i ka intake o ka enterosorbent a me ka laxative. Hoʻokomo pū ka ʻaumua i ka hoʻokele intravenous i ka paʻakai. Inā kūpaʻa ka bradycardia i ka mālama ʻana, hoʻokipa a hoʻokomo i kahi pacemaker kūlohelohe. E hoʻohana pono a hemodialysis.

Ka kuʻikahi me nā mea ʻē aʻe, inu wai

Hiki ke hoʻonui ʻia ka hana o ka lisinopril me ka hoʻoliʻi ʻana i ka terapi diuretic a i ʻole ka hoʻokō ʻana o nā lāʻau pono antihypertensive. ʻO nā vasodilator i hoʻohana, nā barbiturates, nā antidepresi tricyclic, nā antagonis kalima, nā β-blockers hiki ke alakaʻi i kahi hopena like. ʻO ka hopena ʻē aʻe e nānā ʻia ke hui pū ʻia me ka acetylsalicylic acid, sympathomimetics, estrogens a i nā lāʻau lāʻehā o ka hui anti-inflammatory a non-steroidal.

ʻO ka hui like ʻana o Lisinopril-Teva a me ka diuretics o ka hui a-potassium sparing a i ʻole ka hoʻomākaukau ʻana i ka paʻakai e hiki ai i ka hyperkalemia. ʻO ka hoʻohui me ka insulin a me ka mea laikini hypoglycemic hiki ke alakaʻi i ka hyperglycemia.

Ma ka waiʻona a i ʻole nā mea kanu e loaʻa ai ka etanol e hoʻonui i ka hopena o ka lisinopril.

ʻO ke ola, kahi noho mālama

Pono e mālama ʻia i ka mālama ʻana i nā lāʻau i kahi wahi hiki ʻole i nā keiki i ke ana o ka nui o ke kumu o ka 25 kiʻekiʻe. Inā hālāwai kēia kūlana, hiki ke hoʻohana ʻia ka lāʻau lapaʻau i loko o 2 mau makahiki mai ka lā i hana ʻia ai.

ʻO ka kumukūʻai awelika o kēlā me kēia pā o Lisinopril-Teva 2.5 mg a i ʻole 5 mg no 125 rubles. ʻO ka lāʻau lapaʻau 10 mg ke kumukūʻai he awelika o 120 rubles no 20 mau ʻāpana a he 135 rubles no 30 mau ʻāpana. E kūʻai ka lāʻau lapaʻau he 20 mg paha ma kahi o 150 rubles no 20 mau papa a me 190 mau rubles no 30 mau pā.

E kūʻai, pono ʻoe e hāʻawi i ka lāʻau lapaʻau me kahi laoa mai nā kauka.

He nui nā analogues o Lisinopril-Teva. ʻO nā mea āpau āpau e kau i kahi mea ikaika - lisinopril. Ke komo nei kēia mau lāʻau:

Aurolyza,
Nā Diroton
Liloaia
Vitopril,
Lysoryl
Lizi Sandoz,
Zonixem
Lysinokol
Lisopril
Dapril
Lysigamma
Scopril
Ueihue
Lisighexal
Solipril
Linotor.

Hoʻopili ʻo Lisinopril-Teva i ka angiotensin-hoʻohuli o ka enzyme, e hāʻawi ana i ka hopena paʻakikī. Lawe ʻia ka lāʻau lapaʻau e pono ai e ke kauka ma ka nui i kikoʻī ʻia, inā ʻaʻole hiki i ka overdose. Ke hui pū ʻia me nā lāʻau lapaʻau ʻē aʻe, ʻokoʻa ka hopena o ka hopena o ka lisinopril.

Nā ʻano hana a me nā hiʻohiʻona

Hoʻohana ʻia ka lāʻau Lisinopril-Teva ma ke kai ʻana i ka wai nui o ka papa papa ʻia me ka nui o ka wai. Hoʻohālikelike ka nui o kēlā me kēia lā ma kahi papa hoʻokahi, pono e hoʻopau ʻia i ka papa holoʻokoʻa i hoʻokahi lā i ka lā a me ka manawa like, me ka ʻole o ka lawe ʻana i nā meaʻai. Koho ʻia ka nui o ka maʻi no kēlā me kēia maʻi e ka haʻi ʻana i ke kauka ma ke kū hoʻokahi.