ʻOhi ʻia ʻo Finlepsin® (ʻulaʻula ʻo Finlepsin®)

No kēia antiepileptickā kumu kalekaiakekahi ʻano ʻano antidepressant, antipsychotic, antidiuretic a analgesichopena. Pili ka hana a ka lāʻau lapaʻau e pili ana i ka blockade. nā pulu kikowaena sodium-gated, ka hāʻawi ʻana i ka hoʻomau o nā membrane o nā neurons overexcited, hoʻohaʻahaʻa iho i ka hoʻokaʻawale o ka synaptic impulses a me ka pale ʻana i nā hoʻokuʻu o nā neurons. Hoʻokuʻu ʻia ka hoʻokuʻu ʻana o kahi waikawa neurotransmitter amino - gūleʻaloaʻa ka hopena hōʻeuʻeu, e kōkua ana e hōʻemi i ka paepae hoʻokelima o ka wahī, a, a, ke kīpē ʻana, ʻo ka hopu ʻana he epileptic.

Hōʻike ʻia ka hopena o ka lāʻau i nā hana hoʻokele epileptic maʻalahi a paʻakikī paha, hiki ke hele pū ʻia me kahi kekona loulou a pela aku. I kēia hihia, kahi hōʻemi i nā hōʻailona hopohopo, hoʻomāʻeha, huhūahoohiolii.

Hōʻike ʻia kēia lāʻau lāʻau me ka lohi, akā piha Hoʻopaukūʻokoʻa o ka ʻaina meaʻai. Loaʻa ka ʻike ʻana o nā mea i loko o ke kino i loko o nā hola 12 me kahi noi hoʻokahi Finardpsin Kauhau 400 mg, ʻoiai e mālama ana i ka pono therapeutic no 4-5 mau hola. I ka manawa like, ua ʻike ʻia nā kūlike o ka neʻe ʻana o ka mea ikaika i ka plasma ma hope o ka hopena therapeutic o 1-2 mau pule. Eia nō naʻe, hilinaʻi kēia ma nā hiʻohiʻona o ka metabolism o ka mea maʻi: ka hoʻemi ʻana o ka hana o ka pūnaehana enzyme i loko o ka ate, he-induction e nā lāʻau ʻē aʻe i lawe ʻia i ka manawa like, ke ʻano o ka mea maʻi, ka nui a me ka lōʻihi o ka mālama ʻana. I loaʻa ʻia e hele nāamaama i loko o ka waiū o ka umauma a ma o ka paepae placental.

Hoʻomoe ka mea hoʻonāukiuki i ka palūʻai me ka hoʻokumu ʻana o nā metabolites koʻikoʻi: carbamazepine-10,11-epoxide - ka hana a me ka hana ole conjugate waikawa glucuronic. ^ E Ha yM. Ma muli o ke kaʻina metabola, kahi metabolite liʻiliʻi o ka emi loa o 9-hydroxymethyl-10-carbamoylacridane i hoʻohuli ʻia, hiki ke hoʻōla i kāna ʻano hana ponoʻī. Lawe ʻia ka hoʻokaʻawale ʻana o ka lāʻau i ka hana o ka urine, hapa me nā feces.

Nā Palapala Finlepsin

ʻO nā hōʻailona nui no ka hoʻohana ʻana iā Finlepsin:

• nā ʻano like ʻole epilepsy
• neuralgia
• ʻeha i ka hoʻoweliweli ʻana i nā maʻi me nā maʻi maʻi
• nā ʻano like ʻole o nā kūlana hoʻohālikelike - nā māla, ke hao, a pēlā aku.
• hue mele hōʻemi,
• nā maʻi noʻonoʻo maʻi.

Nā Hoʻohui

ʻAʻole i kuhikuhi ʻia ʻo Finlepsin no:

• haaheo i kāna mau māhele a i ʻole luanaole anti
• nā mea hōʻeha o ka puʻu hematopoiesis,
• pālāmole mea paʻa porphyria,
• Paʻi AV
• ka hoʻohana ʻana o ka hoʻomākaukau lithium a i ʻole nā ​​pale o MAO.

Hoʻomaopopo ʻia ka mālama ʻana i ka mālama ʻana o nā maʻi me ka decompensated paleka ka hopena o ka naʻau, ka hoʻokaʻina o ka hyponatremia, ka ate a me nā maʻi ʻōpio, nā poʻe ʻelemakule, ka hoʻōho ikaika ʻana, ka mālama ʻana i ka hematopoiesis pumehana o ka iwi, ʻoiai ke lawe nei i kekahi mau lāʻau lapaʻau, ka prostpl hyperplasia, hoʻonui i ke kōkōlike intraocular, a pēlā aku.

Nā hopena ʻokoʻa o ka finlepsin

Ma ke kānāwai, nā hopena hopena i ka wā o ka mālama ʻana me kēia lāʻau lapaʻau e ulu ma muli o nā keu nui a i ʻole ka piʻi nui ʻana i ka neʻe ʻana o ka mea hana ma ke kino. I ka nui o nā hihia, ua ʻike ʻia ka loaʻa ʻana o nā ku e ka neʻe ʻana o ka ʻōnaehana ma ka manawa. āhāhuʻe,ataxia, drowsiness, nawaliwali laulā, ʻeha a pela aku. Hiki ke hoʻololi pū ʻia. nā hopena kūloheloheno ke kuhi urticaria, erythrodermanā ʻili pehu a me nā hōʻailona ʻē aʻe.

Hiki i ka maʻi hematopoietic a me ke koko ke pane: leukopenia, thrombocytopenia, eosinophilia, leukocytosis, lymphadenopathy. ^ E Ha yM. ʻĀnō ka ʻōleʻa o ka wili ʻana i ka pānaehana ʻana: paakiki, holo, kahakai, hoonui i ka hana o gamma-glutamyl transferase, hana a me nā transaminases hepatic, nā ninia a i ʻole constipation.

Eia kekahi, pilikia nā mea pili me ka ʻōnaehana endocrine a me ka metabolism: hiki i ke huehue, ka nui ʻana o ka wai, ka nui o ka paona, huʻi, hyponatremia a pela aku. ʻAʻole e hoʻoponopono ʻia ka hoʻolālā ʻana o nā kūlō i nā hana o nā ʻōnaehana cardiovascular a me urogenital, ka ʻōnaehana musculoskeletal a me nā ʻatikala sensory.

ʻO nā papa Finlepsin, nā ʻōlelo e pili ana i ka hoʻohana ʻana (ke ʻano a me ke ʻano)

Kuhi ʻia kēia lāʻau lapaʻau no ka hoʻoponopono ʻana i ka waha, me ka ʻole o ka hoʻohana ʻana i nā meaʻai.

I ka mālamaʻana epilepsy Papa papa ʻia e like monotherapy. Inā pili ʻo Finlepsin i ka lāʻau antiepileptic, a laila e hana maʻalahi kēia, ma ka pale maoli ʻana i ka dosage. I nā hihia kahi i kahila ʻia ai ka pōpeka, pono koke ʻia, no ka mea he pau ʻole, akā pono ʻoe e hōʻihoʻi i ka mea i hele mai me ka pālua ʻelua.

Wahi a nā kuhikuhi i ka hoʻohana Finardpsin Kauhau, ke mau maʻi maʻi ʻōpiopio ma ka hoʻomaka ʻana o ka hana e kuhikuhi ʻia i kahi la i kēlā me kēia lā o 200-400 mg. A laila, hiki i ka hoʻonui ʻana i ka dosage ke hiki, e ʻae i ka hoʻokō pono ʻana i mau pono. ʻO ka hoʻoponopono mālama lā i kēlā me kēia lā - 800-1200 mg, ʻoiai kēia huina e māhele ʻia i nā dosis he 1-3. Pono e hoʻolōʻihi ʻia ka nui o ka lā ma nā lā he 1.6-2 g.

No nā keiki, ka hilinaʻi o ka lāʻau lapaʻau i ka makahiki. Eia kekahi, ke paʻakikī i kahi keiki ke lawe i ka paila piha, hiki ke hopu ʻia, nahu a hoʻokaʻawale ʻia i kahi wai liʻiliʻi.

Ua ʻōlelo ʻia nā keiki 1-5 makahiki 100-200 mg, e hoʻoulu ka laha i kēlā me kēia lā i mea e hiki ai ke hana maikaʻi loa.

Hoʻomaopopo ʻia nā keiki he 6-10 mau makahiki e hoʻomaka i ka mālama ʻana me ka mālama ʻana i kēlā me kēia lā Finardpsin Kauhau 200 mg, a laila hoʻonui pinepine ʻia ka dosis.

ʻO ka inikua mua i kēlā me kēia lā no nā keiki he 11-15 mau makahiki he 100-300 mg. Ma hope o kēlā me ke hoʻonui pinepine ʻia e 100 mg a hiki i ka hopena maikaʻi loa.

Ka nui o ka mālama ʻana i nā lā i kēlā me kēia lā: no nā mea maʻi liʻiliʻi 1,5 mau makahiki, 200–400 mg, 6-10 mau makahiki ma ka 400-6600 mg, 11-15 makahiki, 600-1-1000 mg, kahi i puʻunaue ʻia i kekahi mau doses.

ʻO ka lōʻihi o ka mālama ʻana e hilinaʻi pololei ʻia i nā hōʻike a me nā ʻano kūʻokoʻa o ka mea maʻi. I kēlā me kēia hihia, ʻo nā hoʻoholo āpau e pili ana i ka lāʻau lapaʻau e noho i ke kuleana o ke kauka. ʻO ka pinepine ke kūkākūkā i ka hopena o ka hōʻemi ʻana i ka make a i ʻole e hoʻokuʻu i ka lāʻau lapaʻau ke kūkākūkā ʻia i ka wā ʻaʻole i loaʻa ka hapanui o ka mea maʻi no 2-3 mau makahiki.

ʻO ka hōʻemi o ka mālama ʻana i kahi hoʻohaʻahaʻa i hōʻemi ʻia ka lōʻihi, mau makahiki 1-2 mau, ma lalo o ka mālama maʻamau o EEG. I kēia hihia, pono nā keiki e noʻonoʻo i ka nui o ka paona a me nā makahiki.

I ka wā o ka mālama ʻia ʻana o nā maʻi ʻē aʻe e like me nā hōʻike, ʻike ʻia ka nui a me ka lōʻihi o ke komo ʻana e ke kauka, i ka nānā ʻana i ka paʻakikī o ka maʻi a me ka mea maʻi.

Ke keu

Me kahi overdose o Finlepsin, hiki i nā ʻano like ʻole ke kūkulu, e hōʻike ana i ka hōʻino ʻana i nā ʻano o nā palupalu, cardiovascular a me nā mea hanu, nā ʻōpū sensory a me nā ʻōnaehana maʻamau.

Hōʻike ʻia kēia: hoʻoweliweli o ka wahī nūna o ka uka, hōʻeha, ka hiamoe, ʻūlohelohe, ahulau, coma, ʻike maka. tachycardiakaʻe ʻana o ke koko, nāwaliwali, ka uha ʻole ʻana o ka ʻōpū, ka edema pulmonary, ke alo, ka luaʻi, ka mālama ʻana i ka urinary, a pēlā aku.

Ua hoʻokumu ʻia ʻaʻole ʻaʻohe antidote no ka mālamaʻana o ka overdose, no laila, lawe ʻia ka hana kākoʻo e like me nā hōʻailona i hōʻike ʻia, i nā pilikia paʻakikī - ma kahi hoʻonohonoho o ke haukapila.

Hoʻohui

ʻO ka hui pū ʻana o kēia lāʻau lapaʻau me Kākoʻo CYP3A4 kumu a hoʻonui ai i ka ʻike carbamazepine i ka hoʻonohonohoʻana o nā kaila koko a me ka hoʻomohala ʻana i nā hopena kūlike. E hui pū me kaʻaahi o CYP3A4 hoʻomaʻemaʻe pinepine i nā metabolismcarbamazepine, ka hoʻohaʻahaʻa ʻana i kona ʻano a me ka hopena therapeutic.

Hoʻohana maʻalahi verapamil, diltiazem, felodipine, dextropropoxyphene, viloxazine, fluoxetine, fluvoxamine, cimetidine, acetazolamide,danazole, desipramine, nikotinamide, aoiaʻe macrolides - erythromycin, josamycin, clarithromycin, troleandomycin, kekahi mau huaʻala - itraconazole, ketoconazole a fluconazole hiki ke hoʻonui koʻikoʻi carbamazepineaka, aka. ^ E Ha yM. ʻO ia ka hana like me ka ʻano like o terfenadine, loratadine, isoniazid, propoxyphenewai huakai, viral pale hoʻohui kino. I kēia hihia, pono ka hoʻoponopono hoʻoponopono a me ke kāohi ʻana o ka ʻike i nā mea i loko o ka plasma.

Hiki i kahi hui ke hoʻopiʻi a hoʻoikaika paha i ka neʻe ʻana paha. felbamate a carbamazepine.

Maikaʻi haʻahaʻa carbamazepine ʻoiai paha: fenobarbital, primidone, metsuximide, phenytoin, fensuximide, theophylline, cisplatin, doxorubicin,rifampicin, clonazepam, valproic acid, valpromide, oxcarbazepine a me kahi o nā mākau lau no nā Hypericum perforatum.

Carbamazepine hōʻemi i ka hoʻoliʻi plasma o nā lāʻau lapaʻau e like me:clobazam, clonazepam, ethosuximide, primidone, digoxin, valproic acid, alprazolam, cyclosporine, tetracycline, haloperidol,nā mākaukau waha estrogen a progesterone a pela aku.

Ua hoʻokumu ʻia kēlā pākalepono hoʻonāwaliwali i ka hopena hoʻōla carbamazepine. ^ E Ha yM. E hoʻohana me paracetamol hoʻonui i nā hōʻemi o nā hopena o nā pika i ka pūpū, e hōʻemi i ka hoʻomehana therapeutic. E hui pū me phenothiazines, pimozide, molindone, clozapine, haloperidol, thioxanthenes, maprotilinea tricyclic antidepressants hoʻohui i ka hopena o ka pale i ka pānaehana o ka nūpepa, nā nāwaliwali i ka hopena anticonvulsant o ka lāʻau.

No laila, i kauoha ʻia iā Finlepsin i nā maʻi, pono ia e hoʻomaopopo koke i ke kauka e pili ana i nā lāʻau a lākou e lawe nei.

ʻO nā mea kālā Finlepsin

Ke hōʻike nei nā mea kikoʻī nui o Finlepsin e nā lāʻau lapaʻau: Actinval, Apo-Carbamazepine, Zagretol, Zeptol, Carbalepsin retard, Carbamazepine, Mazepin, Stazepin, Storilat, Tegretolme nā mea ʻē aʻe.

Ua hoʻokumu ʻia kēlā carbamazepinehoʻemi i ka hoʻohaʻahaʻa ethanol. Akā i ka inu ʻana i ka waiʻona i nā manawa e hōʻike ʻia ai kēia lāʻau lapaʻau, hiki iā mākou ke manaʻo i ka ulu ʻana o nā hopena ʻaoʻao a me nā ʻōmole like ʻole.

ʻO nā loiloi no Finlepsin

I ka nui o nā hihia, haʻalele nā ​​mea hoʻohana e pili ana i nā manaʻo Finardpsin KauhauKēia mau makahiki a lākou i aloha ai i kā lākou mea aloha. ʻO kekahi mau poʻe maʻi e ʻeha nei epilepsy, e nānā i ka lawe ʻana i kēia lāʻau lapaʻau e pili pono i kā lākou hana naʻauao, ke alakaʻi ʻana i ka hoʻomohala a me ka kamaʻilio ʻana o ka nohona. Eia naʻe, me kēia mau hōʻailona, ​​e hōʻoia i nā mea maʻi i ka hana kiʻekiʻe o ka lāʻau lapaʻau, e ʻae iā ʻoe e poina i ka hoʻouka ʻana.

Aia nā loiloi i ka wā i hoʻohana ai ʻo Finlepsin i ka mālama ʻana i nā hōʻeha panic e pili ana i ka makaʻu i ka hāmama, a i ʻole, i nā wahi i pani ʻia. Ma muli o ka mālama ʻana, ma ka hapa nui, nalo ka panikina, akā naʻe kekahi hopohopo i ka gait e hoʻomau ka hopohopo.

No laila, ʻo Finlepsin kekahi o nā huahana anticonvulsant maʻamau a me nā lāʻau antiepileptic i hoʻohana maikaʻi ʻia i loko o ka hana lapaʻau. Wahi a nā poʻe loea, ʻo ka mālama ʻana me kēia mea hana e hiki ai iā ʻoe ke hoʻokō i nā hopena kupaianaha. ʻO ka mea nui ka hoʻokō pono me nā ʻōlelo kau a pau a nā kauka, e pili ana i ka nui o nā lāʻau a me nā ʻano e ola ai, e ʻike maopopo ai i ke kumu o ka papa Finlepsin a lawe wale iā lākou e like me nā hōʻike.

E hoʻokuʻu i ke ʻano a me ka hoʻohui lāʻau

Loaʻa ka Finlepsin Retard i ke ʻano o nā papa no ka hoʻokele waha. He keʻokeʻo nā papa papaʻa, puni, me ka pilikia ma kekahi ʻaoʻao, i hoʻopili ʻia i nā alapine he 10 mau ʻāpana (5) i loko o kahi pahu pahu. Hoʻopili ʻia kahi hoʻohālikelike me kahi wehewehe kikoʻī i ka lāʻau lapaʻau.

Aia i kēlā me kēia papa pākuʻi hoʻonaninani Carbamazepine 200 mg a i 400 mg, a me kekahi helu o nā mea kōkua: microcrystalline cellulose, magnesium stearate, gelatin.

ʻLoe a me ke kākele

Hoʻonohonoho ʻia ka nui o ka lāʻau i kēlā me kēia e ke kauka, e pili ana i nā hiʻohiʻona o ke kino o ka mea maʻi a me nā maʻi.

ʻO ka hoʻomaka mua o ka lāʻau no nā poʻe ʻōpio a me nā wā'ōpiopio ma mua o 14 mau makahiki he 100-400 mg i ka lā. Ma ka haʻalele ʻana o kahi hopena a i ʻole ka lawa o ka hopena ma lalo o ka mākaʻi ʻana o ke kauka, hoʻonui ʻia ka nui o ka maʻi e ka 200 mg i kēlā me kēia lā me kahi 1 mau pule. Wahi a ka pākuʻi lā i kēlā me kēia lā, ua hoʻokaʻawale ʻia ka lāʻau i nā ona he 1-4, ʻoi ʻia ke kīloi koke i ka papa me ka nui o ka wai.

No nā keiki i lalo o 6 mau makahiki o ka make ʻana, e helu ʻia ka nui o ka lāʻau ma ke kumu o nā mea kaupaona o ke kino - 10 mg / kg i kēlā me kēia lā, ua hoʻokaʻawale ʻia ka nui o ka lāʻau ma loko o nā 2-3. Manaʻo nā keiki mai ka 6 a hiki i ka 14 makahiki o 200 mg o ka lāʻau i kēlā me kēia lā, ua māhele ʻia ka nui o ka make i 2 mau maʻi. Inā lawa ka hopena, ma hope o 1 hebedoma e hiki ke hoʻonui ʻia ka nui o ka lāʻau ma ka 100 mg. ʻO ka palena kiʻekiʻe loa i kēlā me kēia lā nā keiki he 1 g, no nā pākeke - 1200 mg.

ʻŌpū a me ka lactation

ʻAʻoheʻike me ka hoʻohana ʻana i ka lāʻau lapaʻau no ka mālama ʻana i nā wahine hāpai i ka trimester mua a me ka palekana o ka carbamazepine no ka ʻōpiopio ʻaʻole i hōʻike ʻia.

ʻO ka hoʻohana ʻana o nā papa ʻo Finlepsin Retard i ka trimesters o 2 a me 3 o ka hapai paha hiki ke loaʻa wale nō inā loaʻa nā hōʻailona koʻikoʻi, i ka mea ke loaʻa i nā pōmaikaʻi no ka makuahine i ʻoi aku ka nui o nā pōpoki no ke keiki hānau ʻole. Hiki ke hoʻohana ʻia ka lāʻau lapaʻau ma loko o ka inika liʻiliʻi liʻiliʻi i loko o ke ʻano o ka monotherapy.

Pono nā wahine e mālama ʻia me nā papa ʻo Finlepsin Retard e hoʻohana i nā contraceptives kiʻekiʻe e pale ai i ka hānau ʻana. Inā hiki i ka wā hānau, a laila pono e nīnau aku kahi wahine i ke kauka a kāpae i ka lawe ʻana i ka lāʻau.

Hiki ke hoʻopili ʻia nā Carbamazepine i loko o ka waiū umauma, no laila he mea pono ʻole e hoʻohana i nā papa ʻo Finlepsin Retard i nā wahine i ka wā o ka lactation. Inā pono ia ia nā lāʻau, e kuhikuhi ʻia ka umauma o ka hōʻeha ʻana i mea e kūʻē ʻole ai i ke pēpē.

Nā hopena hopena

I ka wā e lawe ai i ka papa ʻaina Finlepsin i nā mea maʻi me ka hoʻonui ʻana i ke ʻano o ka mea pilikino i nā mea o ka lāʻau, hiki i nā hopena ʻaoʻao:

• mai ka pūnaehana nūhou - ka ʻeha, ka hopohopo i ka mea e hana nei, ataxia, huki, hoʻonaninua ʻelua, nā ʻeha, ka huhū me ka haki ʻana o nā limahana, ka haunaele o ka noho ʻana, nā paresis, nā ʻuhala, ka neuritis, ka nāwaliwali o ka naʻau, ke kaumaha, ka huhū, ka haunaele o nā ʻono ʻono i ka pae o ka mea i hōʻea, nā leo. a kani ana i na pepeiao
• mai ka hanu ʻana mai - glossitis, stomatitis, hoʻemi i ka makemake, ʻawaʻī, nausea, luaʻi, hepatitis, ʻeha o ka ʻōpū, hoʻonui i ka hana o nā transaminases hepatic, ʻeha kūwaho,
• mai ka pūnaehana cardiovascular - kahalaha puʻuwai poloka, atrioventricular block, maʻi vascular incufficiency, thrombophlebitis, thromboembolism, hoʻomōhala o ka puʻuwai puʻuwai,
• mai nā ʻenehana hemopoietic - kahi emi o ka nui o leukocytes, platelets, agranulocytosis, anemia, hemolytic anemia,
• system endocrine a me metabolism - hyponatremia, impaired calcium metabolism, gynecomastia, galactorrhea, thyroid dysfunction, hoʻonui kolesterol, edema, kaohi paʻa ʻana,
• mai nā kino urinary - hana renal impaired, renal failed, interstitial nephritis,
• maʻi kūlohelohe - weli i ka ʻili, ke kauā, ka ʻōpū i nā lymph nīnū, ʻulaʻula i ka ʻili.

Inā hele a loaʻa paha nā hopena ʻē aʻe, pono e nīnau aku ke ahonui i ke kauka no ke aʻo ʻana.

Nosological ʻano papa (ICD-10)

Lapaʻau lāʻau

He lohi a pau ka holopapa (ʻo ka ʻai ʻana ʻaʻole i pili i ka helu a me ka nui o ka inu ʻana). Ma hope o hoʻokahi kakawahine ʻo ka pōkole C_max hiki i nā hola he 32 .. Pau loa C_max i nā mea ikaika e hoʻololi ʻia ma hope o hoʻokahi ka manawa o 400 mg o ka carbamazepine ma kahi o 2,5 μg / ml. C_{ai ʻo ss} hōʻea ka lāʻau lapaʻau i loko o ka plasma i 1-2 mau pule, ʻo ka nui o ka hoʻokō i kau ʻia i kēlā me kēia kumuhana o ka metabolism (auto-induction o nā ʻōnaehana enzim, hetero-induction e nā lāʻau lapaʻau ʻē aʻe i hoʻohana pū ʻia i ka manawa like, a me ka kūlana o ka mea maʻi, ka nui o ka lāʻau a me ka lōʻihi o ka mālama ʻana. Nui nā ʻike kūʻokoʻa i nā waiwai C i ʻike ʻia._{ai ʻo ss} i ka hopena therapeutic: ma ka hapanui o nā maʻi, nā helu ma waena o 4 a 12 μg / ml (17-50 17mol / l). ʻO nā mea o ke kūama o ka mau ʻoama o ka carbamazepine-10,11-epoxide (ka metabolite hoʻākāka lāʻau pharmacologically) e pili ana i 30% o ka kūlike o ka carbamazepine.

Ke kamaʻilio pū ʻana me nā protein plasma i nā keiki - 55–59%, i nā pākeke - 70-80%.

Kahi V_{e d} - 0.8-1.9 l / kg. Hoʻokumu ʻia nā kukū i loko o ka wai a me nā lawaiʻa cerebrospinal, kahi mea i hoʻohālikelike ʻia i ka nui o nā mea kaha a me nā protein (20-30%). Penetrates ma o ka paepae placental. ʻO ka hoʻoulu ʻana i ka waiū umauma he 25-60% o kēlā me ka plasma.

Hoʻomili ia i ka ate, ka mea nui i ka ala epoxy me ka hoʻokumu ʻana o nā metabolites koʻikoʻi: ka kaha o ka carbamazepine-10,11-epoxide a me ka hana o ka conjugate me ka waikawa glucuronic. ʻO ka isoenzyme nui e hāʻawi ana i ka biotransformation o ka carbamazepine i ka carbamazepine-10,11-epoxide ka cytochrome P450 (CYP3A 4). Ma muli o kēia mau hopena metabolic, kahi hana kekahi o ka metabolite o ka 9-hydroxymethyl-10-carbamoylacridane, ka mea nāwaliwali kahi hana lapaʻau.

Hiki i ka Carbamazepine ke hōʻoki i kona ake ponoʻī. T_1/2 ma hope o ka hoʻoponopono waha ʻana o kekahi maʻa he 60-100 mau hola (ma ka nui o 70 mau hola), me ka hoʻokele lōʻihi ʻana o T_1/2 ka emi ʻana ma muli o ka autoinduction o nā ʻōnaehana o ka huina. Ma hope o ka lawelawe waha ʻana o ka carbamazepine, ʻo 72% o ka nui i lawe ʻia i loko o ka pāʻai a me ka 28% i loko o nā feces, me kahi kokoke o 2% o ka huehue i hoʻopili ʻia i loko o ka urine e like me ka carbamazepine i loli ʻole, ma kahi o 1% i loko o kahi ʻano o kahi metabolite 10.11-epoxy.

ʻAʻohe mea hōʻailona i ka loli o ka pharmacokinetics o ka hoʻololi o ka carbamazepine i nā mea maʻi maʻi.

Hōʻikeʻike Indicationspsin ®

ka maʻi ʻepekema o ka epilepsy (me ka hoʻokaʻawale ʻana i nā hemahema), nā ʻāpana wahi o ka epilepsy (maʻalahi a me nā ʻōhumu paʻakikī), nā kuʻuna ākea kūhelu nui).

neuralgia trigeminal,

ʻurallelo, nā hana neuralgia idiotathic

ʻeha me nā ʻōwili o nā niperi pōkole o ka maʻi ma ke ʻano maʻi, ʻehaʻeha i ka neuropathy maʻi maʻi,

epileptiform hoʻokūkū i ka lehulehu sclerosis,

facial spasms me ka neuralgia trigeminal,

kaʻaila tonic, paroxysmal disorders o ka ʻōlelo a me nā neʻe (paroxysmal dysarthria a me ataxia),

nā paroxysmal paresthesias a me nā pale nui o ka hōʻeha,

Hōʻemi i ka waiʻona alkohol (hopohopo, hoʻāhewa, hoʻōho, hoʻāla no ka hiamoe,)

nā maʻi psychotic (affective a me schizoaffective disorders, ʻokaʻeha, nā pilikia o ke ʻōnaehana wāwae).

E hoʻokuʻu i ke ʻano a me ka ʻano

Loaʻa ka retlepsin retard i ke ʻano o nā papa pālahalaha lōʻihi: mai ke keʻokeʻo me kahi melemele pāpaʻi a keʻokeʻo, pālahalaha, puni, nā kihi o nā papa i beveled, hoʻopiʻi ʻia kahi pale hoʻowalewale i kēlā me kēia ʻaoʻao, he 4 kie ma ka ʻaoʻao ʻaoʻao (10 ʻāpana i nā palaka, ma ke kāleka kahi pākeke o 3, 4 a i ʻole 5 mau blisters).

Pākaukau 1 papa:

• mea waiwai: carbamazepine - 200 a i 400 mg,
• Nā haʻawina kōkua: triacetin, copolymer Eudragit RS30D methyl methacrylate, ethyl acrylate a trimethylammonioethyl methacrylate (1: 2: 0.1), copolymer Eudragit L30D-55 (ethyl acrylate, methacrylic acid), crospovidone, silicon dioxide colloidal, selolosa, selolosa

Nā ʻōkuhi no ka hoʻohana ʻana i ka retard Finlepsin: ʻano a me ka ʻihi

Hōʻalo ʻia nā Finlepsin papa 200 mg a 400 mg i ka waha o ka wā a ma hope o ka ʻai ʻana a holoi ʻia me ka wai o ka wai, wai a i ʻole nā ​​ʻano wai ʻē aʻe.

Inā makemake ʻia, kahi hoʻopau hoʻoneʻe mua o ka hopena o ka lāʻau i loko o kahi wai i ʻae ʻia, ʻaʻole i ʻole ʻia kona waiwai pharmacological.

Ua mahele ʻia ka ʻōhua o kēlā me kēia lā i ka dosis. ʻO ka palena kiʻekiʻe loa o kēlā me kēia lā he 1.6 g.

Palapala ʻia i kēlā me kēia lā:

• mālama ʻana i ka epilepsy. ʻApiopio: ke kau o ka mua (hoʻokahi manawa, i ke ahiahi) ʻo 0.2-0.4 g, pono e hoʻonui iki ʻia ka nui a hiki i kahi hopena e loaʻa ai ka hopena therapeutic maikaʻi loa i ka mea maʻi. ʻO ka pae ʻōlelo mālama mālama he 0.8–1.2 g. Ua mahele ʻia i 2 mau ō: 0.2-0.6 g i ke kakahiaka a me 0.4-0.6 g i ke ahiahi. mau makahiki (hoʻokahi, i ke ahiahi) - 0.2 g, ua lohi ka liki (0.1 g i kēlā me kēia lā) e loaʻa ai ka hopena maikaʻi loa. ʻO ka dosis mālama mālama no nā keiki he 6-10 mau makahiki he 0.4-0.6 g, ua māhele ʻia i 2 mau minamina i ka pae e hiki mai ana: i ke kakahiaka - 0.2 g a i ke ahiahi - 0.2-0.4 g. nā kamaliʻi 11-15 mau makahiki he 0.6-1 g: i ke kakahiaka - 0.2-0.4 g, i ke ahiahi - 0.4-0.6 g. ʻO ka lōʻihi o ka hana lapaʻau e hilinaʻi ʻia ma ke ʻano o ka maʻi o ka mea maʻi a me ka hoʻomanawanui pilikino o ka lāʻau. . ^ E Ha yM. ʻO ke koho ʻana o ka retard Finlepsin e like me ka monotherapy koho ʻia. ʻO ka hoʻokomo ʻana i ka lāʻau i loko o ka lāʻau antiepileptic i hoʻokō ʻia, pono e hana maʻalahi, inā pono, e hoʻoponopono ʻia i ka pau ʻana o nā lāʻau lapaʻau concomitant. Inā poina ʻoe i ka laʻi aʻe aʻe, hiki iā ʻoe ke lawe iā ia inā ʻaʻole ia e pili i ka hoʻokahakuhua ʻana o ka maʻi ʻelua o ka lāʻau. Ke hoʻoholo nei ke kauka i ka hoʻoholo i ka hoʻoneʻe ʻana i ka mea maʻi i ka mālama mea hoʻokele Finlepsin, ʻo ka lōʻihi o ka hoʻohanaʻana a i ʻole ke kāpae i ka lāʻau lapaʻau pilikino. Hiki ke hoʻohaʻahaʻa i ka ʻona a i ʻole ke kāpae i ka lāʻau lapaʻau wale nō me ka hala ʻole o ka hopu ʻana i loko o nā makahiki 2-3. Hoʻomaʻamaʻa ka mālama ʻana no 1-2 mau makahiki, e hoʻohaʻahaʻa i ka hopena ma lalo o ka kāohi o ka electroencephalography. I nā keiki, me ka hoʻohaʻahaʻa i nā lā i kēlā me kēia lā, pono e noʻonoʻo i ka hoʻonui ʻia ʻana o ka makahiki i ka nui o ke kino,
• nā hoʻopaʻi epileptiform me ka sclerosis lehulehu: 0.2-0.4 g,
• ʻO ka neuralgia trigeminal a me ka idiopathic glossopharyngeal neuralgia: ke kau mua ʻana he 0.2-0.4 g, hōʻike ʻia kona hoʻonui a hiki i ka ʻeha ʻana o ka ʻeha. ʻO 0.8 g ka nui loa ma kēlā me kēia lā maʻamau ʻo 0.4 g. ʻO ka dosis mua loa i nā poʻe maʻi maʻi a i ʻole ka ʻike pilikino o ka hana o ka carbamazepine ma kahi o 0.2 g hoʻokahi i ka lā.
• ʻeha hōʻeha i ka maʻi diabetes neuropathy: 0.2 g i ke kakahiaka a me 0.4 g i ke ahiahi. I nā hanana kūʻokoʻa, e hoʻokō i ka hopena therapeutic, hōʻike ʻia ke kāula Finlepsin i ke kakahiaka a me ke ahiahi ma ka paina o 0.6 g,
• ka mālama ʻana i ka maʻi hōʻemi o ka waiʻona ma kahi o ka haukapila: ka maʻamau 0.6 g (0.2 g i ke kakahiaka a me 0.4 g i ke ahiahi), i nā maʻi koʻikoʻi, 1,2 g i nā lā mua. Hiki ke hoʻohui pū ʻia ka lāʻau lapaʻau me nā lāʻau ʻē aʻe i hoʻohana ʻia e mālama ai i ka hoʻōmi ʻana i ka ʻona. ʻAʻole hiki iā ʻoe ke hoʻohui me ka Finlepsin retard me nā sedatives a me nā hypnotics. E pono e mālama pono ka nānā ʻana i ka mokuʻāina o ka mea maʻi. Pono e mālama pū ʻia ka hoʻomaʻamaʻa ʻana me ka mālama pinepine ʻana o ka pae o ka carbamazepine i loko o ke koko koko,
• nā psychoses (mālama a me ka pale ʻana): ʻo ka mua a me ka mālama mālama ʻana he 0.2-0.4 g. ʻO ka nui loa ma kēlā me kēia lā he 0.8 g.

Nā ʻōlelo kikoʻī

ʻO ka palena o ka hopena o ka carbamazepine i ka hoʻomohala ʻana o ka maʻi antipsychotic malignant, ʻoiai inā i hui pū ʻia me ka antipsychotics, ʻaʻole i paʻa.

Hiki ke hoʻomohala ʻia ka hopena o ka hopena mai ke kikowaena o ka nūnū pokole e ka pili o ka nui o ka lāʻau a i ʻole ka piʻi nui ʻana i ka pae o ke kūpaʻa o ka carbamazepine i loko o ke kaila koko.

Hiki ke hana wale ʻia ke koho ʻana iā Finlepsin i hiki ke nānā ʻia ke kauka pinepine o ke kauka no ke ʻano o ka mea maʻi.

E kūʻē i ke kūmole o ka hoʻohana o ka lāʻau lapaʻau, aia kahi hopena o nā hana suicidal a i ʻole makemake paha, nā ʻano o ka mana i ʻike ʻole ʻia. ʻO nā mea maʻi, ʻike ʻia nā ʻohana a me nā limahana e pili ana i kēia a pono e ʻimi koke lākou i ka mālama olakino inā e loaʻa ana nā hōʻailona o ka hana suicidal.

Ke koho ʻana i kahi laila mua a me ka mālama mālama e hāʻawi ana i ka hopena kūpono loa, e aʻo ʻia e hoʻoholo i ke kiʻekiʻe o ka carbamazepine i loko o ke koko koko, ʻoi aku paha i ka ʻōlelo ʻana mai ʻo Finlepsin ma ke ʻano o ka hui hoʻohui ʻana, no ka mea, me ka hoʻokūkū wikiwiki e hōʻemi ʻia e ka hoʻohuihui o ka ʻohiʻohi o ka mikrosomal a i ʻole ka hui ʻana o nā lāʻau lapaʻau like, hiki i ka mea maʻi. he ʻai ʻokoʻa loa ʻana i kahi ʻoihana i manaʻo ʻia.

ʻO ka hiki koke ʻana o ka hoʻokaʻawale ʻana ʻo Finlepsin hiki i ka hoʻokau epileptic, no laila inā ʻoe e hoʻohuli koke i ka hoʻōla ʻana i ka maʻi maʻi, e hoʻokaʻawale ʻoe i kekahi lāʻau antiepileptic ma lalo o ka uhi o ka intravenous (iv) a i ʻole ka hoʻoponopono ʻalepale o diazepam, phenytoin (iv) a i ʻole nā ​​mea ʻē aʻe i hōʻike ʻia i kēlā mau hihia.

Hoʻohālikelike ʻia ka hoʻohana ʻana i ka waiʻona e pili ana i ke ʻano o ka hoʻohana ʻana i ka lāʻau.

Hoʻololi ʻia ka hoʻololi i ka mālama me ka carbamazepine ma ka hoʻoemi haʻahaʻa ʻana i ka make ma mua nā lāʻau antiepileptic i lawe ʻia ma mua.

ʻAʻole pono nā wahine o nā makahiki hānau hānau i nā contraceptives oral hormonal, no ka mea ʻaʻole lākou e hāʻawi i ka contracept e hiki ke hana i ka koko intermenstrual.

Pono e mālama pū ʻia nā pale me ka nānā pinepine ʻana i nā hōʻailona hana pili i ka ate, ka mea nui i nā mea maʻi a me nā poʻe maʻi me ka mōʻaukala o ka maʻi ate. Me ka hoʻolālāʻana o ka maʻi pūpū nui, pono e hoʻopau koke iā Finlepsin retard.

I ka helu ʻana i ka lāʻau lapaʻau i ka 4 mau pule o ka mālama mua, i ka hebedoma a laila hoʻokahi manawa i kēlā me kēia 4 hebedoma, pono e alakaʻi i ke ʻano he koko e hoʻoholo ai i nā helu platelet, reticulocytes, pae hao, urea, a me ka paʻa serule electrolytes. Eia kekahi, pono kahi urinalysis maʻamau, electroencephalography.

Pono e hoʻokaʻawale ʻia ke ʻano maʻi no ka leukopenia me nā hōʻailona koʻikoʻi o kahi pathology infectious a leukopenia holomua paha.

ʻO ka hiʻohiʻona o ka hopena o ka ʻili o ke kino ma ke ʻano o kahi mahele macular maculopapular a i ʻole hoʻi ke koi i ka haʻalele ʻana o ka retle Finlepsin, neʻe aku nā hōʻailona ma luna o lākou, ʻo ke ʻano ma hope o ka hoʻohaʻahaʻa ʻana i ka hopena o ka lāʻau. I kēia manawa hana, pono ka mea maʻi i ka nānā o kekahi kauka. Inā loaʻa iā ʻoe kahi hopena hypersensitivity, nā hōʻailona o ka maʻi Stevens-Johnson a i ʻole ʻo Lyell syndrome, pono ʻoe e hoʻōki i ka lawe ʻana i nā papa.

Pono ke kauka e hoʻomaopopo i ka mea maʻi e pili ana i ka hiki ke hoʻomau ʻia o nā hopena o nā mea maʻi, ka hōʻike ʻana o nā hōʻailona mua i hiki ke maʻi, ka ʻōpala, ka ʻehaʻeha, ka ʻōpala o ka mucosa waha, ka hanana o hematomas, hemorrhages a purpura. No ka manawa kūpono o kēia mau ʻōuli, pono ʻoe e nīnau i ke kauka.

Ma mua o ka hoʻomaka ʻana i ka hoʻomaʻamaʻa ʻia, ʻike ʻia ka mea maʻi e hoʻomaʻamaʻa i ka hoʻokolokolo ophthalmological. Me ka piʻi ʻana o ka intraocular pressure, pono e mālama ʻia ʻo ia e lawe ana i ka carbamazepine.

I nā maʻi koʻikoʻi o ka pūnao cardiovascular, ka mea hōʻino i ka poupa a me (a) paha i nā hina, a me ka poʻe no ka wā kahiko, ʻoi ʻia e hoʻohana iā Finlepsin retard i nā haʻahaʻa haʻahaʻa.

Hoʻololi ʻia ka pae maʻamau o ka pae o ka carbamazepine i loko o ka plasma inā he manaʻo kānalua no ka hōʻeuʻeu ʻana o kona kīnā ʻana, e kāohi i ka hana maʻamau o ka lāʻau lapaʻau ʻana e ka mea maʻi, me ka piʻi nui o ka piʻi, i ka wā hapai, i ka mālama ʻana i nā keiki, me nā hōʻailona o nā hopena ʻona.

Hoʻohui nūhou

Me ka hoʻohana ʻana o ka hoʻokele Finlepsin:

• inhibitor o ka isoenzyme CYP3A4: hiki i ka nui o ka hoʻonui i ka pae o ka carbamazepine i loko o ke kaila koko a me ka hoʻomohala ʻana i nā hopena kūpono ʻole,
• hiki i nā mea o ka isoenzyme CYP3A4: hiki i ka wikiwiki o ka hana o ka metabolama o ka carbamazepine a me kahi hoʻēmi ʻana i kona kaila plasma a me ka hopena therapeutic. Eia naʻe, ke hoʻokuʻu ʻia nei ka nui o ka neʻe o ka carbamazepine, no ka mea i emi ka nui o ka biotransformation,
• ʻO MAO inhibitors: hiki i ka hoʻomohala ʻana o nā ulu ʻana o ka hyperthermic a me ka hypertensive crises, seizure, hiki ke make, no laila, ʻo ka manawa ma waena o kā lākou intake e lilo i ʻelua mau pule,
• ka hoʻomākaukau ʻana o ka lithium: e hoʻonui i ka hopena me ka hopena neurotoxic o kēlā me kēia lāʻau lapaʻau,
• verapamil, nikotinamide, diltiazem, desipramine, felodipine, danazole, dextropropoxyphene, acetazolamide, viloxazine, cimetidine, fluoxetine, fluvoxamine, macrolides - clarithromycin, josamycin, troleandomycinina, eryromole , propoxifene, ritonavir a me nā mea hou aku i ka protease inhibitors no ka mālama ʻana i ka maʻi o ka maʻi immunodeficiency virus: hoʻonui i ke kahe o ka carbamazepine i loko o ke kō koko, no laila, ka nānā ʻana i ke kiʻekiʻe o ka carbamazepine i loko o ka plasma a i ʻole hoʻoponopono ʻana i kāna kāʻei kapu,
• valproic acid, primidone: neʻe i ka carbamazepine mai ka pilina me nā protein plasma, hiki ke hoʻonui i ka kaila o ka metabolite hoʻākāka ʻo pharmacologically (carbamazepine-10,11-epoxide) a me ka hoʻomohalaʻana i nā hopena maikaʻi loa.
• fenobarbital, primidone, phenytoin, metsuximide, fensuximide, rifampicin, theophylline, cisplatin, doxorubicin, clonazepam, valpromide, oxcarbazepine, acid acid, hoʻōlaʻai, hoʻomākaukau no ka lāʻau o John John wort perforated: hiki ke kōkua i ka hoʻēmi ʻana o ka wai,
• felbamate: kumu i ka hoʻohaʻahaʻa o ka pae o ka carbamazepine a me ka hoʻonui ʻana i ka ʻike o carbamazepine-10,11-epoxide i ka plasma koko, kahi hoʻolōʻihi i ka manawa like i loko o ka neʻe i ka serum koko a hiki i ka hopena o ka felbamate.
• isotretinoin: hoʻololi i ka bioavailability a (a) i huikala ʻia o ka carbamazepine, o ka carbamazepine-10,11-epoxide,
• fenothiazine, pimozide, thioxanthenes (chlorprotixen), molindone, haloperidol, maprotiline, clozapine, tricyclic antidepressants: hoʻonāwaliwali i ka hopena anticonvulsant o ka lāʻau lapaʻau, e hoʻonui ana i ka hopena o ka inhibitory ma ka pūnaehana mikina waena.
• clobazam, clonazepam, prednisone, digoxin, ethosuximide, prednisolone, valproic acid, prednisolone, alprazolam, dexamethasone, cyclosporine, methadone, doxycycline, haloperidol, theophylline, oral contraceptives me estrorochenoric, orarromeric, orarromeric ), topiramate, lamotrigine, antidepresan tricyclic (amitriptyline, imipramine, clomipramine, nortriptyline), clozapine, oxcarbazepine, tiagabin, inhibitor protease - indinavir, ritonavir a me saquinavir, levothyroxine, b nā hānela channel koho kai ʻona dihydropyridine (felodipine), midazolam, olanzapine, tramadol, praziquantel, risperidone, ziprasidone, itraconazole: hoʻohaʻahaʻa i kā lākou pae plasma a me kā lākou hopena therapeutic.
• tetracyclines: e hoʻonāwaliwali i ka hopena therapeutic o ka carbamazepine,
• myelotoxic lāʻau: kumu i hoʻonui ʻia hematotoxic hōʻike o carbamazepine,
• anticoagulants kūleʻa, contraceptives hormonal, acid folic, praziquantel: hoʻoikaika i kāu metabolism,
• paracetamol: hoʻoluhi i kona kaohiʻana, e alakaʻi ana i ka hoʻonui i ka hopena o nā hopena o ke kōpaʻa i ka puhaka a me ka hoʻolilo ʻana i ka hana pono o ka paracetamol,
• hydrochlorothiazide, furosemide (diuretics): hāʻawi i ka hoʻopuka ʻana o ka hyponatremia me nā hōʻike pilikino,
• Nā pancuronium a me nā mea hoʻoleʻā ʻole o nā pale hoʻomaha hōʻeha: nāwaliwali i kona hopena, koi ʻia ka hoʻoponopono ʻana,
• hiki i nā hormone thyroid: hiki ke hoʻonui i ka kinai,
• enflurane, halothane, fluorotan (anesthetics): hoʻoikaika i kāu metabolism, e hoʻonui nei i ka hopena o ka hopena hepatotoxic,
• methoxyflurane: hoʻonui i ka hana o kona mau nephrotoxic metabolites,
• isoniazid: hoʻonui i ka hopena hepatotoxic,
• ethanol: hoʻonui i kona hopena.

ʻO nā analogues o nā hāmeʻa Finlepsin he Finlepsin, Carbamazepine, Apo-Carbamazepine, retard Carbalepsin, Zagretol, Zeptol, Mazepin, Tegretol, Stazepin, Storilat.

He aha ka mea ʻo Finlepsin Retard

ʻO Finlepsin, i kau ʻia ma ka radar ʻo Finlepsin retard, ka ʻohana o ka pharmacological o nā lāʻau antiepileptic e hoʻoponopono i ka laka ʻana, e hōʻoluʻolu ana i nā hopu, ʻeha a me nā hōʻike ʻē aʻe o ka neuralgia. ʻO ka lāʻau ma hope o ka hoʻomaka ʻana o ka hoʻokele e loaʻa he anticonvulsant, antidepressant, analgesic hopena.

ʻO ka poʻe me nā maʻi neuralgic e hoʻomaopopo i ka hōʻemi ʻana o ka ʻeha, ua emi ka hopohopo. ʻO ka hana ikaika o Finlepsin e kōkua i ka pale ʻana i nā kao sodium-hilinaʻi, hoʻonā i nā membrane o nā neurons overexcited, hōʻemi i ka hoʻoneʻe ʻana o nā impulses, a hōʻemi i ka hopena o ka hoʻomohala ʻana a me ka hana hou ʻana i ka lawe epileptic.

ʻO ka inoa inoa hoʻoili honua ʻole o ka lāʻau lapaʻau, a i ʻole INN - carbamazepine, ʻo ia ka mea ikaika e Finlepsin. Hoʻohana ʻia nā mea kōkua:

• ka leʻaleʻa talcum
• ammonium methacrylate,
• konekena stearate,
• crospovidone
• likina silika
• gelatin.

Ma hope o 1-2 mau lā o ka hoʻokele ʻana, hoʻopau iki ʻia ka carbamazepine i loko o ke kino, a ma hope o hoʻokahi pule ua lawa ke kō koko o ka mea maʻi no ka hopena therapeutic. Hiki iā ia ke komo i loko o ka pale Plental, no laila e lawe ʻia ʻo Finlepsin me ka akahele i ka wā hapai, e noʻonoʻo pono e kamaʻilio me nā kauka.

E hoʻokuʻu i nā palapala

Loaʻa ka Finlepsin i ke ʻano o nā papa melemele a i ʻole ke keʻokeʻo me ka hopena lōʻihi, me ke ʻano he 200 a me 400 mg o ka hana ikaika. Loaʻa i kēlā me kēia pahuhopu he 10 mau ʻāpana. Kēia mau maʻi i ka hoʻohaʻahaʻa haʻahaʻa ʻia no nā keiki a me nā poʻe me nā maʻi hōʻemi o ka neʻe ʻana ma ka hoʻomaka ʻana o ka mālama ʻana, no laila ʻaʻole e hoʻolauna i nā hoʻopiʻi koʻikoʻi.

Ma hope o ka hoʻohou nui ʻana o ke kino, hoʻonui ʻia ke ʻano ma ka manaʻo o ke kauka e nānā ana i ka mea maʻi a hiki i ka hopena i makemake ʻia. Hoʻomaopopo ʻia ka ʻike ʻana iā Finlepsin-400 e hoʻomaka me nā papa 0.5, e ʻimi paʻa pono i nā ʻōkuhi a ʻike ʻia inā ua hui pū ʻia nā lāʻau lapaʻau a me nā ʻoihana ʻē aʻe. Ma kahi kīleʻa, kūʻai ʻia nā papa Finlepsin i loko o nā pahu kāleka o nā 3, 4, 5 bele.

ʻ a me ke kākele

Ma waho o nā ʻōlelo kikoʻī a kāu kauka, he ʻae ʻia ka hoʻoponopono ʻana i kēia maʻa no ka finlepsin 200 retard. Eʻoluʻolu e pili pono i nā palapala i kauoha ʻia e kāu kauka, no ka mea, inā ʻaʻole finlepsin 200 retard e loaʻa kahi hopena therapeutic!

Ehia mau a pehea pehea ʻoe e lawe ai i ka finlepsin 200 retard

Hoʻomaʻamaʻa maikaʻi ka mālama ʻana me ka finlepsin 200 retard, e kuhikuhi ana i ka lāʻau lapaʻau ma nā haʻahaʻa haʻahaʻa no kēlā me kēia maʻi, e pili ana i ke ʻano a me ka paʻakikī o ka maʻi. A laila e hoʻonui mālie ʻia ka nui a hiki i ka hopena mālama pono loa. ʻO ka hopena kūpono o ka lāʻau no ka mea maʻi, ʻoi aku me ka hui pū ʻana, e hoʻoholo ʻia e kona pae plasma. E like me ka ʻike i hōʻiliʻili ʻia, ʻo ka hoʻomehana therapeutic o finlepsin 200 retard i ka plasma he 4-112 μg / ml.

E hoʻopili i hoʻokahi antiepileptic me finlepsin 200 retard e hana lohi ʻia, e hōʻemi i ka pauʻana o ka lāʻau lapaʻau mua. Inā hiki, kahi hoʻohana antiepileptic wale nō e hoʻohana i ka monotherapy. ʻO ka papa kūpono o ka mālama ʻia e mālama ʻia e kekahi kauka loea.

ʻO ka laulima maʻa ʻānela i loaʻa ʻia he 400-112 mg o ka finlepsin 200 mau papa o ka lā, i hoʻokaʻawale ʻia i nā dosis he 1-2 i kēlā me kēia lā. Ke piʻi nei i ka nui o nā lā i kēlā me kēia lā he 1200 mg ʻaʻole kūpono. ʻAʻole pono ʻoi loa ka nui o kēlā me kēia lā ma 1600 mg, no ka mea, hiki i nā dosis kiʻekiʻe ke hoʻonui i ka nui o nā hopena like.

I kekahi mau hihia, hiki i ka nui o ka lāʻau i manaʻo ʻia no ka mālama ʻana ke neʻe i ka nui mai ka mea i hoʻolako ʻia ai ka hoʻomaka ʻana a me ka mālama mālama ʻana, no ka laʻana, no ka metabolism wikiwiki ʻana ma muli o ka hoʻoluhi ʻana o ka puʻukuhina mikrosomal a i ʻole ma muli o ke kaila o ka lāʻau i loko o ka hoʻohui hui.

Ma waho o nā ʻōlelo kūikawā a ke kauka, ke alakaʻi ʻia nei lākou e ke ʻano hoʻohālike o ka hoʻohana ʻana i ka lāʻau lapaʻau.

Hoʻohana ʻia Anticonvulsant

Ma ka laulā, i ka pākeke, ke kau pinepine nei ka nui o nā papa he 1-2 o ka pā (e pili ana i ka 200-400 mg o ka carbamazepine) e hoʻonui pinepine ʻia i kahi papa mālama i nā papa papaʻa o ka 4-6-6 o kahi o nā retard (e pili ana i ka 800-11200 mg o ka carbamazepine).

Ma keʻano holoʻokoʻa, ʻo ka mālama mālamaʻana i ka haʻama o nā carbamazepine no nā keiki haʻahaʻa e 10-20 mg / kg momona kino o ka lā.

Hoʻolaha ʻia ka papa kuhikuhi papa inoa.

Kuhi ʻia nā ʻōpio i ke kakahiaka / ahiahi200-300 mg i ke ahiahi 200-600 mg 400-600 mg Kau ʻia nā keikisee kime mai 6 a 10 mau makahiki i ke ahiahi150-200 mg i ke ahiahi200 mg i ke kakahiaka 200-400 mg 11 ke 15 mau kakahiaka me ke ahiahi150-200 mg i ke ahiahi200-400 mg 400-600 mg

No nā keiki ma lalo o 6 mau makahiki o ke ʻano, no ka mālama mua a me ka kākoʻo, aia i nā papa o nā hana ʻaʻole lōʻihi. Ma muli o ka nele o ka ʻike i loaʻa me nā papa retard, ʻaʻole lākou e ʻae ʻia no nā keiki i kēia makahiki.

ʻO ka pale ʻana i ka hoʻomohala ʻana o ka hopu pōkole me ka hoʻokaʻawale ʻana i ka waiʻona ma kahi haukapila

ʻO ka awelika o kēlā me kēia lā he 1 papa papa o ka hoʻihoʻi i ke kakahiaka, i ke ahiahi 2 ua kuhikuhi ʻia nā papa ʻelua o ka retard (e pili ana i ka 600 mg o ka carbamazepine). I nā hihia koʻikoʻi, hiki i ka lā mua, hiki ke hoʻonui ʻia i ka nui i 3 mau papa o ka hōʻina i 2 mau manawa i kahi lā (e like me 1200 mg o ka carbamazepine).

ʻAʻole pono e hui pū ʻo Finlepsin 200 i nā lāʻau lapaʻau sedative-hypnotic. E like me nā koina hauoli, akā naʻe, inā pono, hiki ke hoʻohui ʻia ka finlepsin 200 retard me nā mea ʻē aʻe e hoʻohana ai no ka mālama ʻana i ka hoʻēmi ʻana i ka wai.

I ka wā mālama, pono ia e kiaʻi pinepine i nā kiko o nā finlepsin 200 retards i loko o plasma koko.

No ka pilina me ka hoʻomohala ʻana i nā hopena ʻaoʻao mai ka pūnaehana waena a me ka autonomic (ʻike i nā ʻano o ka hoʻemi ʻana o ka ʻaluna ma ka ʻāpana "Side effects"), hoʻokūpaʻa ʻia ke nānā ʻana no nā maʻi.

Neuralgia Trigeminal, genuin glossopharyngeal neuralgia

ʻO ka maʻa mua loa he 1-2 mau papa o ka paila (e pili ana i ka 200-400 mg o ka carbamazepine), kahi, a nalowale ka ʻeha nui, hoʻonui ʻia e ka nui o 2-4 mau papa o ka paila (e like me 400–800 mg o ka carbamazepine), kahi i hoʻoili ʻia i 1-2 mau pākahi. lā. Ma hope o kēlā, i kekahi mahele o nā mea maʻi, hiki ke hoʻomau ʻia ka mālama ʻana me kahi hoʻohaʻahaʻa haʻahaʻa haʻahaʻa, hiki iā ia ke pale aku i nā hōʻeha ʻana o ka ʻeha o ka papa ʻaina o 2 mau manawa i kahi lā (e like me ka 400 mg o ka carbamazepine).

No nā mea maʻi a me nā mea maʻi koʻikoʻi, ua kau ʻia nā mea he 200 finlepsin i loko o ka pniha mua o 1 papa pā o ka ʻimi i hoʻokahi lā i ka lā (e like me ka 200 mg o ka carbamazepine).

ʻEha i ka maʻi neuropathy maʻi

ʻO ka awelika o kēlā me kēia lā he mau papa ʻaina i ka kakahiaka a me nā papa he 2 mau ahiahi ma ke ahiahi (e like me 600 mg o ka carbamazepine). I nā hihia kūʻokoʻa loa, hiki ke kuhikuhi ʻia ka hope o finlepsin 200 i loko o ka pākaʻi o 3 mau papa o ka paila 2 mau manawa i ka lā (e like me ka 1200 mg o ka carbamazepine).

ʻO ka hoʻopaʻapaʻa Epileptiform i nā sclerosis lehulehu

ʻO ka awelika o kēlā me kēia lā he 1-2 mau papa ʻaina 2 mau manawa i kahi lā (e like me 400–800 mg o ka carbamazepine).

Hoʻomaʻamaʻa a me ke pale aku i ka maʻi maʻi

ʻO ka dosis mua, ʻo ka mea maʻamau ka lawa ma ka mālama mālama ʻia, ʻo ia hoʻi nā papa ʻelua retard i kēlā me kēia lā (e like me 200-400 mg o ka carbamazepine). Inā kūpono, hiki ke hoʻonui ʻia kēia ʻauʻau i nā papa papaʻa 2 i mau manawa 2 i ka lā (e kūpono me ka 800 mg o ka carbamazepine).

ʻO nā maʻi me nā maʻi cardiovascular koʻikoʻi, nā poho o ka ʻōpala a me nā huehue, a me nā poʻeʻelemakule e kuhikuhi pū ʻia i nā palapala haʻahaʻa o ka lāʻau.

Pehea a pehea e lawe ai i ka finlepsin 200 retard

Ua hoʻolako ʻia nā papa retard me kahi alawai hoʻokaʻawale, lawe ʻia i ka wā a ma hope o ka ʻai ʻana, holoi ʻia me ka wai me ka nui wai (no ka laʻana, he kīʻaha wai).

Hiki ke kiʻi i nā papa papa lāʻau ma hope o ka hānai ʻana o ka mua i loko o ka wai (ma ke ʻano o kahi hana hoʻōki). Ke hoʻomau nei ka hana lōʻihi ma hope o ka papaʻa ʻana o ka papaʻaina i ka wai.

I kekahi mau manawa, ua hōʻike ka maikaʻi o ka hoʻoili ʻia o nā maʻi o kēlā me kēia lā i 4-5 mau pōpoki hoʻokahi i kēlā me kēia lā. No kēia, ʻoi aku nā kūpono dosage o nā hana he wā lohi ʻole.

Pehea ka lōʻihi e lawe ai iā finlepsin 200 retard

Ma muli o ka hōʻike a me ka pane kūʻokoʻa o ka mea maʻi i ka lāʻau lapaʻau.

Hana ʻia ʻo Epilepsy i ka lōʻihi. Pono ke kauka loea e hoʻoholo i ke neʻe ʻana o ka mea maʻi e finlepsin 200 retard, ka lōʻihi o ka hoʻohana a me kona wehe ʻana i kēlā me kēia hihia. Ma kahi ākea, hiki iā ʻoe ke hoʻokaʻawale i ka palena o ka lāʻau lapaʻau a hoʻopau ʻole i ka mālama ʻana inā ʻaʻole ma mua o ka hala o ka 2-3 mau makahiki o ka hopu ʻana.

Hoʻopauʻia ka mālamaʻana e kahi emi hōʻemi o ka hopena o ka lāʻau no 1-2 mau makahiki. I kēia hihia, pono e noʻonoʻo nā keiki i ka hoʻonui ʻana o ka paona kino. ʻAʻole pono nā hōʻailona o ka EEG.

I ka mālamaʻana i ka neuralgia, mea pono ke kuhikuhi i ka finlepsin 200 retard i ka mālama mālama ʻia, lawa wale nō e hoʻomaha ai i ka ʻeha, no kekahi mau pule. Ma ka haʻahaʻa ʻana i ka make, pono ia e hoʻoholo inā ua kala ʻia ka kala ʻole i nā hōʻailona o ka maʻi. Me ka hoʻi hou ʻana o ka hōʻeha ʻana o ka ʻeha, hoʻomau ʻia ka mālama ʻana me ka maʻi mālama o mua.

ʻO ka lōʻihi o ka mālama ʻana i ka ʻeha ma ka neuropathy maʻi diabetes a me nā mea hoʻihoʻi epileptiform i nā ʻōpū he nui e like nō no ka neuralgia.

Hoʻomaʻa ka mālama ʻia ʻana o ka maʻi hoʻonāukiuki waiʻona me ka finlepsin 200 mau mea a ka hōʻemi ʻana me ka hoʻohaʻahaʻa nui ʻana i ka manawa 7-10 mau lā.

Ke mālama ʻia nei nā hoʻomaʻamaʻa ʻana o nā kaʻina manic-depressive i lōʻihi.

ʻO nā hewa i ka hoʻohanaʻana i ka lāʻau lapaʻau a me ka overdose

Inā poina e lawe ʻoe i ka wai hoʻokahi o ka lāʻau lapaʻau, a laila ʻike koke ʻia ʻoe, lawe koke. Inā ma hope o kēia e lawe i ka ʻōkuhi i hōʻike ʻia, a laila e pili iho ʻoe i ia, a ma hope o ka hoʻāʻo hou e komo i kāu hoʻoponopono kaulike. Ma kahi hihia ʻole, ma hope o hoʻokahi kau kala e hoʻopoina ʻia, mai lawe i kahi pālua ʻelua o finlepsin 200 retard. Ma ka hihia o ka kānalua, e ʻoluʻolu e hāʻawi i kāu mea e mālama ai i kāu olakino kōkua no ke kōkua!

ʻO ka mea e pono ai ʻoe e noʻonoʻo inā makemake ʻoe e hoʻopilikia a ulia paha i ka mālama ʻana

Ke hoʻololi nei i ka dosis ponoʻī a kāpae paha i ka lāʻau lapaʻau me ka ʻole o ka nānā ʻana i ke kauka he pōʻino! I kēia hihia, e piʻi hou paha nā hōʻailona o kou maʻi. Ma mua o kou ho'ōki ʻana e lawe i ka finlepsin 200 ulana iā ʻoe iho, pono ʻoe e kamaʻilio i kāu kauka e pili ana i kēia.

He aha ka mea e hana inā lawe ʻia nā finlepsin 200 i mea nui

ʻO ka overdose o ka lāʻau pono e koi i ke komo ʻana o ka lāʻau mālama maʻi. Hōʻike ʻia ka kiʻi o ka overdose o finlepsin 200 retard i ka piʻi ʻana o ka hopena ma lalo, e like me ka haʻalulu (nā nui), nā aʻe ka mea i ka wā e hauʻoli ai ka lolo (nā koina tonic-clonic), ka kahi huki, a me ka hana ʻana o ka hanu a me ka hana cardiovascular me ka hoʻēmi pinepine ʻana. (i kekahi manawa i hoʻokiʻekiʻe ʻia) ke kahe o ke koko, piʻi i ka nui o ka naʻau (tachycardia) a me nā haunaele o ka leʻaleʻa i ka puʻuwai (atrioventricular block, e hoʻololi i ka ECG), ʻike hou ʻole i ka naehana hopu a me ka cardiac hopu. I nā hihia i neʻe ʻia, ua nānā ʻia ka leukocytosis, leukopenia, neutropenia, glucosuria a i ka acetonuria, i hoʻokumu ʻia e nā hōʻailona hoʻololi i nā hana hoʻokolohua.

ʻAʻohe mea antidote kiko'ī no ka mālamaʻana i ka puhī o ka maʻi me ka finlepsin 200 retard. Hoʻohana ʻia ka mālama ʻana o nā overdoses o finlepsin 200 mau mea hoʻokele, ma ke ʻano he kānāwai, e mālama ʻia ana i nā hōʻike hōʻeha i loko o ka haukapila.

ʻO nā hopena ʻaoʻao i nānā pinepine ʻia i ka mālama like me ka monotherapy. Wahi a ka maʻi nui a ma ka hoʻomaka ʻana o ka mālama ʻana, hiki mai paha nā hopena like ʻole:

Kaleponi ʻenehana kikowaena / noʻonoʻo

ʻO Stupor o ka ʻike, ʻike ʻole (hopohopo), ʻeha, nāwaliwali, naʻō o ka lewa a me ke neʻe (cerebellar ataxia) a me nā maʻi hōʻeha pinepine. Hiki i nā poʻe maʻi ke kūkulu i ka haunaele a me ka hopohopo.

Ma nā hihia kaawale, ʻike ʻia ka ʻuhane kaumaha, nā ʻano hana ʻino, lethargy o ka noʻonoʻo ʻana, impoverment o nā motives, a me nā maʻi hoʻi ʻānia (hallucinations) a me nā tinnitus i nānā ʻia. Ke mālama nei me ka finlepsin 200 retard, hiki i ka psychent psychose ke hana.

Loaʻa pinepine ʻia nā neʻe i neʻe, e like me ke koʻikoʻi nui, nā hōʻiliʻili o ka ʻili, a i ʻole ka twitching o ka lālani (nystagmus). Eia kekahi, i nā poʻe maʻi maʻi a me nā luʻu o ka lolo, hiki ke hōʻeha ʻia nā hana ʻoi e hoʻokūkū ana, e like me ka neʻe ʻana o ka neʻe i ka wahi rotolitic ma ke ʻano o ka grimacing (rotolitic dyskinesias), ka neʻe ʻana i ka puli (choreoathetosis). ʻO kekahi mau hihia o ka hoʻopiʻi ʻana i nā maʻi, nā hōʻike hewa ʻole, nāwaliwali o ka naʻau, ka hana ʻana o ka nerve (peripheral neuritis), a me nā hōʻike ʻana o ka maʻi pālule ma lalo o ka parakuis (paresis) a me nā maʻi ʻono ʻano ʻono.

Hoʻopau wale ka hapa nui o kēia mau mea i ko lākou mau ma hope o 8-14 lā a i ʻole ma hope o ka hōʻemi iki ʻana i ka pona. No laila, inā hiki, hiki i ka finlepsin 200 retard ke dile me ka makaʻala, e hoʻomaka ana ka mālama ʻana me nā dosis haʻahaʻa, a laila e hoʻonui mālie iā lākou.

Na maka

I kekahi mau hihia, aia me ka palipila o ka membrane hoʻohui o ka maka (conjunctivitis), i kekahi manawa he mau hele ma nā hiʻohiʻona ʻike (nā hana ʻino ma ka noho ʻana o ka maka, ʻike pālua ʻia, ʻike maka. Ua hōʻike ʻia nā kuahiwi o ke kīpē.

I nā maʻi me ka glaucoma, pono ia e hoʻopaʻa pinepine i ka paipai intraocular.

ʻŌnaehana propulsion

Ma nā hihia hoʻokaʻawale, ua ʻike ʻia ka ʻeha i nā ʻōpū a me nā ʻōpū (arthralgia, myalgia) a me nā ʻuʻupu uaua. Ua neʻe aku kēia mau hanana i ka pau ʻana o ka lāʻau lapaʻau.

ʻO ka ʻili a me nā membus

Ua hōʻike ʻia nā hopena o ka maʻi o ke ʻano maʻi o ka maʻi a me ka ʻole o ka maʻi o ka maʻi, e like me ka wā pinepine a i ʻole ka pinepine ʻana o ka urticaria (urticaria), ka ʻeha, i nā manawa nui a nā palaki peʻahiʻu scaly (exfoliative dermatitis, erythroderma), nā nekrosis o ka ʻili o ka ʻula me ka blistering (syndrome Lyell), photosensitivity (photosensitivity), ʻulaʻula me ka ʻili polymorphic i ke ʻano o nā wahi a me ka hoʻokumu ʻana o nā nodes, me nā hemorrhages (e exudative erythema multiforme, erythema nodosum, Stevens syndrome Johnson), petechial hemorrhages i loko o kaʻili, a me ka systemic lupus erythematosus (lupus erythematosus hoʻolaha).

Ma nā noho ākea a nānā ʻole paha, ʻike ʻia nā luhi o ka lauoho (alopecia) a me ka lula (diaphoresis).

ʻŌnaehana a me ka lymphatic

Ma ka pili me nā hopena hypersensitivity ma ka mālama ʻana o finlepsin 200 mau mea hoʻokele, ʻo ka hoʻohui, a me nā hanana hoʻohua koko ma lalo iho nei: pinepine a piʻi pinepine paha (leukocytosis, eosinophilia) a hoʻoemi paha (leukopenia) i ka nui o leukocytes a platelets (thrombocytopenia) i loko o ke koko peripheral. Wahi a ka puke nūpepa, ʻike pinepine ʻia ka leukopenia maʻamau (transient i ka 10% o nā hihia, a hoʻomau ma ka 2% o nā hihia).

Ua hōʻike ʻia ma nā hihia pili i ka maʻi koko, i kekahi manawa he hoʻoweliweli ʻia, e like me ka agranulocytosis, aplastic anemia, a me nā ʻano like ʻole o ka anemia (hemolytic, megaloblastic), a me ka hoʻonui pū ka spleen a me nā lymph node.

Me ka ʻike o ka leukopenia (neutropenia ka manawa pinepine), thrombocytopenia, pulima ka maʻi ʻulaʻā (exanthema) a me ke ala maʻi finlepsin 200 mau paʻa.

ʻŌpala Gastrointestinal

I kekahi manawa ke nalowale i ka makemake o ka makemake, waha maloʻo, nilo a me ka luaʻi, hele aʻai a i ʻole constipation hiki pinepine ai. ʻO nā hihia i hoʻohālikelike ʻia i ka ʻōpū a me ka hoʻowalewale o ka me nā mucous o ka waha o ka oropharynx (stomatitis, gingivitis, glossitis) i hōʻike ʻia. Ke hele nei kēia mau hanana i hope iā lākou iho ma hope o 8-14 lā o ka mālama ʻana a ma hope o ka hoʻohaʻahaʻa iki ʻana i ka hopena o ka lāʻau. Hiki iā lākou ke pale aku ma ke koho mua ʻana i nā wīwī haʻahaʻa o ka lāleʻa me kā lākou hoʻonui pinepine ʻana.

Aia i kahi mau hōʻailona ma ka puke paʻi hiki i ka carbamazepine i kekahi manawa ke hōʻeha i ka maʻi pancreas (pancreatitis).

Hōʻalo a me ka ʻili

I kekahi manawa ke ʻike ʻia nā loli o ka hoʻāʻo ʻana o ka hana maʻa mau, i nā hanana lohi e loaʻa mai ai ka hana ʻana; i nā hihia loaʻa ʻole, nā ʻano like ʻole o ka hepatitis (cholestatic, hepatocellular, granulomatous, hui ʻia).

Ua hōʻike ʻia ʻelua mau hihia o ka porphyria intermittent.

Hālau ka mulu, ka wai a me ka paʻakai paʻakai

ʻO nā hihia i hoʻohālikelike ʻia i ka umauma nui o nā kāne (gynecomastia) a me ka hoʻopuka waiū i ka waiū mai nā momona mammary i nā wahine (galactorrhea) i hōʻike ʻia.

Hiki i ka retard Finin 200 ke hoʻopilikia i nā ʻōmaʻomaʻo o ka thyroid function (triiodothyronine, thyroxine, hormone thyroid-stimelling a me ka free thyroxine), ka mea ke hui pū me nā lāʻau antiepileptic ʻē aʻe.

Ma muli o ka hana o ka finlepsin 200 retard, e hōʻemi ana i ka ʻāʻī ʻana o ka urine mai ke kino (ka hopena antidiuretic), i nā hanana ka hopena, i ka emi ʻana o ka sodium serum (hyponatremia) e nānā ʻia, hoʻopili ʻia e ka luaʻi, ʻeha a me ka hilahila.

ʻO nā hihia kaawale o ka like o ka edema a me ka hoʻonui nui i ke kaupaona kino i mālama ʻia. Hiki i ka Finlepsin 200 Retard ke hoʻohaʻahaʻa i nā pae kalumona serum. Ma nā hihia kaʻawale, alakaʻi kēia i ka palalupua i nā iwi (osteomalacia).

Nā ʻōpū hanu

ʻO kekahi mau hihia o ka hopena o ka hoʻonui ʻia ʻana o ka māmā o ka māmā i ka lāʻau lapaʻau, e hele pū ana me ke kuni, ka pōkole o ka hanu (dyspnea), nā maʻi maʻi a me ka fibrosis pulmonary.

Palapala genitourinary

Kēia hiki mai nā hana renal impaired, i hōʻike ʻia e ka nui o ka nui o ka protein i loko o ka urine (proteinuria), ke ʻano o ke koko i ka urine (hematuria), i hoʻoneʻe i ka ʻopihope o ka urine (oliguria), i nā hihia lohi e ulu a hiki i ka holopū ʻole. ʻO kēia mau pilikia paha ma muli o ka hopena antidiuretic intrinsic o ka lāʻau. I kekahi manawa dysuria, pollakiuria a me ka mālama ʻana i ka urinary.

Eia kekahi, ʻike ʻia nā hihia o nā hana kolohe wahine, e like me ka hala a me ka hoʻohaʻahaʻa i ka makemake moekolohe.

ʻŌnaehana Cardiovascular

Ma nā hanana a ʻokoʻa paha, ʻo ka mea nui i ka poʻe elemakule a i nā mea maʻi me nā maʻi puʻuwai ʻike ʻia, he hōʻemi i ka nui o ka puʻuwai ma ke ala (bradycardia), nā kuʻuna o ka puʻuwai puʻuwai, a me ka hopohopo e pili ana i ka maʻi naʻau coronary.

Loaʻa kekahi mau hewaʻole o ka leʻaleʻa i ka puʻuwai (atrioventricular block), i nā hihia kūʻokoʻa i hele pū me ka nāwaliwali. Eia kekahi, i kekahi mau hihia, hoʻemi ʻia ke koko a piʻi paha. ʻO ka hāʻule o ke kaʻe koko ke loaʻa nui me ka hoʻohana ʻana i ka lāʻau lapaʻau i nā papa kiʻekiʻe.

Eia kekahi, ua nānāʻia ka vasculitis, thrombophlebitis, a me ka thromboembolism.

Hypersensitivity hopena

Ua lohi ka hopena o ke ʻano o ka hypersensitivity i ka lāʻau lapaʻau, hiki i ka hiʻona, ka ʻehaʻeha, ke ʻano ʻōwili, ke kīwī i nā lymph nīnū, hōʻeha hui, ka nui o nā keʻena koko keʻokeʻo i ke koko peripheral, ka nui a me ka pōpoki, a me ka loli i nā ʻāpana ʻokoʻa o ka hana e hiki ai i nā ʻokoʻa ʻē aʻe hui pū kekahi, a hoʻopili pū me nā ʻokoʻa ʻē aʻe o ke kaʻina, e like me ka ʻōpala, nā ʻōpū, ka pancreas a me ka myocardium.

I nā lā kaʻawale, ua nānā ʻia kahi ʻano maʻamau o ka maʻi a me ka hoʻoneʻe ʻana o ka meninges me ka myoclonus a me ka eosinophilia.

Inā ʻike ʻoe i nā hopena pili i hōʻike ʻole ʻia i loko o kēia kau inoa, e ʻoluʻolu e ʻike i kāu kauka a i ʻole mea hoʻohana lāʻau lapaʻau e pili ana i kēia.

He aha nā hana e pono ai me nā hopena ʻaoʻao

Inā ʻoe e ʻike i nā hopena hopena i hōʻike ʻia, a laila e hoʻomaopopo koke i kāu kauka e hoʻoholo i kā lākou hōʻeha a e hana i nā mea e kūʻē ai iā lākou (e ʻike i ka ʻāpana "Hoʻomohala no ka hoʻohana"). ʻO ka maʻa mau loa a laila, kahi ʻeha, ʻehaʻeha, kūloko o ka maʻi pakanā i ke ʻano o nā rashes me nā lymph node a me / a i ʻole nā ​​maʻi hōʻeha i ka wā o ka mālama ʻana me nā retardpsin 200 retard, pono ʻoe e kamaʻilio koke i kahi kauka a hoʻoili i ke kiʻi koko.

Me ka hoʻolālāʻana o nā hopena kūlohelohe koʻikoʻi, hoʻopau koke ka finlepsin 200 retard.

Inā kū kekahi mau loli i ke kiʻi koko (leukopenia, neutropenia pinepine, thrombocytopenia), huʻu ʻulaʻelima (exanthema) a me ke ala o ka finlepsin 200 mau keke.

Inā aia nā hōʻailona o ka hōʻeha o ka ate a i ʻole ka hana ʻole, e like me ka lethargy, ka nele o ka make nui, ka ʻōpū, ke kala ʻulaʻula a i ʻole ka hoʻonui ʻana i ka ate, e ʻimi koke i kahi kauka.

Hoʻolaha ka lā

3 mau makahiki
Hoʻomaopopo ʻia ke ola o nā papa retard i ka foil o ka pale kaula blister a ma kahi pahu pahu.
Ma hope o ka manawa i ʻōlelo ʻia, mai hoʻohana i nā papa pākuʻi hou o kēia haki.

ʻO nā lāʻau lapaʻau e mālama ʻia i ka hiki ʻole i nā keiki!

Hiki mai ʻo Finlepsin 200 retard i kahi pale palekana palekana keiki paha me kahi paila pale e ʻoi aku ka palekana. Ma ka hihia he mea paʻakikī iā ʻoe ke kāwili i ka papa kalepa, a ma mua o kēia hana ʻana i kēia hana, ke aʻo aku nei mākou iā ʻoe e hoʻoulu hou i ka ʻili e uhi.

Nā kūlana mālama

Mālama ʻia ka lāʻau ma lalo o nā kūlana maʻamau.

E hoʻokuʻu i nā palapala

Loaʻa nā hāleau o Finlepsin 200 i nā paena o 50, 100, a me nā papa 200 heʻe.

ʻŌpū a me ka lactation

I ka manawa hiki, ʻōmole Finlepsin ® i ʻōlelo ʻia i nā wāhine o ka hānau ʻana me ke ʻano monotherapy, ma kahi pāʻina liʻiliʻi pālua, e like me ʻoi aku ka nui o ka malenations ʻana o nā pēpē hou mai nā makuahine i lawe i ka ʻano antiepileptic hui ʻia ʻoi aku ka ʻoi me ka monotherapy.

I ka wā e loaʻa ai ka hapai, pono e hoʻohālikelike i ka pono o ka lapaʻau ʻia a me nā hoʻopiʻi hiki paha, ʻoi aku hoʻi i ka trimester mua o ka hāpai ʻana.

Ua ʻike ʻia na keiki o nā makuahine e loaʻa ana i ka epilepsy i predisposed i ka ulu ulu ʻana o ka hana hōʻeuʻeu a me ke kino, me ka malformations. Hiki i ka retard Finlepsin ® ke hoʻonui i ka hopena o kēia mau pilikia. Aia ma kahi kaʻawale o nā hihia o nā maʻi a me nā malformations, e komo me ka pani ʻole ʻana o nā pahe vertebral. (spina bifida). ^ E Ha yM. Hoʻonui ka lāʻau antiepileptic i ka nele o ka folic acid, i ʻike pinepine ʻia i ka wā hāpai, hiki iā ia ke hoʻonui i ka nui o ka hānau ʻana o ka hānau ʻana i nā keiki, no laila, ʻo ka lawe ʻana i ka waikawa folic e ʻōlelo ʻia ma mua o ka wahine i hoʻolālā ʻia a i ka wā hāpai. I mea e pale ai i nā hoʻopiʻi hemorrhagic i nā mea hou, ua ʻōlelo ʻia i nā wahine i nā mau pule hope o ka wā o ka hāpai ʻana, me nā pēpē hou,

Hōʻalo ka Carbamazepine i ka waiū umauma, no laila ʻo nā pōmaikaʻi a me nā hopena i makemake ʻole ʻia e like me nā hopena o ka umauma pono e hoʻohālikelike me ka hoʻomau ʻana i ka maʻi maʻamau. Me ka umauma hoʻomau i ka wā e lawe nei i ka lāʻau lapaʻau, pono ʻoe e hoʻokumu i ka nānā ʻana no ke keiki e pili ana i ka hiki ke hoʻomohala ʻana i nā hopena ʻino (ʻoi aku ka hoʻohuhōlohi, hoʻohālikelike nui ʻia, ʻano loea.

Mea hana

Koea Teva Operals Poland Sp. z oo, st. Mogilska 80, 31-564 Krakow, Polani.

ʻO ka inoa o ke ʻano loea i nona ka inoa o ka palapala kākau inoa kau inoa. Teva Pharmaceutical Enterprises Ltd., Israel.

Hoʻouna ʻia nā noi o nā mea kūʻai aku i ka helu: 115054, Moscow, ul. Kahi, 35.

Kelepona: (495) 644-22-34, fax: (495) 644-22-35 / 36.

Nā ʻōkuhi no ka hoʻohana ʻana iā Finlepsin retard

Wahi a nā ʻōlelo kuhikuhi, ʻaʻole pono ke ʻano o ka lāʻau lapaʻau me ka ʻai nui ʻana i ka meaʻai, no laila hiki iā ʻoe ke inu iā ia i kēlā me kēia manawa. No ka mālamaʻana o ka epilepsy, hoʻohana ʻia ʻo Finlepsin e like me ka monotherapy, me ka ʻole e hoʻopili me nā lāʻau lapaʻau ʻē aʻe. Hoʻolālā ʻia ka dosage no nā makahiki like ʻole, e hoʻomaka me ka liʻiliʻi a me ka hoʻonui pinepine ʻana. E like me nā kauoha a nā pākeke, ua hoʻohana ʻia nā dopala o kēlā me kēia lā.

• mua - 200-400 mg,
• kūlia a kākoʻo paha - 800-1200 mg,
• ʻo ka nui he 1600-2000 mg.

Loaʻa kēia hapa o ka carbamazepine i kēlā me kēia kanaka, ua mahele ʻia i 3-4 mau wā. Inā hala ʻole ka mea maʻi i kahi paila no kekahi kumu, a laila ʻaʻole ʻoe e inu i ʻelua manawa i hoʻokahi e pale ai i kahi overdose. I ka mālamaʻana i nā keiki, hilinaʻi ka nui o kēlā me kēia lā nui, hoʻonui i ka 100 mg a hiki i ka hopena i makemake ʻia:

• 1-5 makahiki - 100-200 i 400 mg,
• 6-10 mau makahiki - 200-300 a 600 mg,
• 11-15 mau makahiki - 300-400 a 1000 mg.

Pono ka lōʻihi o ka lawe ʻana iā Finlepsin e hoʻoponopono ʻia e ke kauka, e nānā ana i ka pono o ka mea maʻi. I kekahi mau hihia, pono i nā makahiki he nui no ka hoʻouka ʻana e hōʻalo. Hoʻemi ʻia ka nui o ka dosage ma hope o ka mālama ʻana a me ka loaʻa ʻole o nā huhui no 2-3 mau makahiki. ʻO ke ala ala maikaʻi loa e hoʻowalewale ai i ka hopena o ka hopena Finlepsin i loaʻa i ka electroencephalogram o ka lolo.

Palapala Uleʻa Finlepsin

Ma hope o ke koho ʻana i kauka, pono ʻoe e kūʻai i kahi ʻano lapaʻau kūpono a hoʻomaka e lawe. ʻO ka ʻokoʻa i ke kumukūʻai no Finlepsin ma St. Petersburg a me Moscow e hilinaʻi ana i ka nui o nā papa, ka ʻaki, ka hoʻomoʻa.

Finlepsin-200, 50 pcs.

Finlepsin-400, 30 pcs.

Finlepsin-400, 50 pcs.

Ke Lūkini, e lawe ʻia ana ke kūʻai aku o nā hāmeʻa Finlepsin e ka mea hana Polokalamu TEVA. Inā ʻaʻole kūpono ka lāʻau lapaʻau no ka mea maʻi, hiki i ke kauka ke koho i kekahi o nā mea hoʻohālike o Finlepsin. He like nā lāʻau lapaʻau, like nā like like. He mea maʻalahi nā analogs, ʻaʻole like me nā kumu mua, akā i nā hopena ʻē aʻe, no laila, ʻaʻole i hāʻawi ʻia e hoʻololi iā Finlepsin iā ʻoe iho.

ʻO ka papa inoa o nā lāʻau lapaʻau antiepileptic maikaʻi e loaʻa:

ʻO Regina, 53 makahiki. Ua inu au iā Finlepsin no 2 mau mahina, i ka manawa i kau ʻia ai e ke kauka iaʻu ma hope o ka hoʻonā ʻana o ka nerve trigeminal. Ua hōʻike ʻia iaʻu he nui nā hopena o ka lāʻau lapaʻau, no laila hoʻomaka wau e lawe i ka hapalua o kahi papa papa i ka mua. ʻAʻole hiki iā ia ke pale aku i kahi hana maikaʻi loa - i ke kakahiaka wau he mau maʻi iki wau, akā inā naʻe ʻo Finlepsin i kōkua iaʻu.

Julia, 35 makahiki. Me ke kōkua o kēia Finlepsin, ua hoʻopilikia wau i ka epilepsy i kahi keiki. Hoʻopili ʻia ka papa papa i ka pala. Pono wau e kau i nā hōʻeha o ka hiamoe a me ka nausea liʻiliʻi, akā no ka makahiki 1 o ke komo ʻana ma lalo o ka nānā ʻana o kekahi loea, ua paʻa mākou e pale i ka lawepili epileptic. Ua hoʻāʻo mākou e huli i kahi lāʻau lapaʻau like, e ʻokoʻa i ke kumukūʻai, akā ʻaʻole kūpono.

ʻO Eugene, 47 mau makahiki ʻo Finlepsin i lilo no ke kaumaha i ka ʻōlelo aʻo a ka mea lapaʻau. Kauoha aku au i kahi kūʻai ma ka hale kūʻai pūnaewele me ka hoʻopuka ʻana ma ka leka uila. I ke kumukūʻai, lilo ia i mea uku ʻole. Hoʻomaʻamaʻa mai ke kauka iaʻu ʻaʻole e hoʻohui i ka Finlepsin a me ka mea inu wai, inā ʻaʻole hiki ke loaʻa nā hopena ʻokoʻa ma mua o ka mea i hōʻike ʻia mai i ka hōʻemi lāʻau. ʻAʻole wau e'ōlelo i ka inu ʻana i ka lāʻau lapaʻau me ka loaʻa ʻole o kahi koho.