Acetylsalicylic Acid MS
ʻO ka rheumatism, rheumatoid arthritis, infectious-allergic myocarditis, pericarditis, rheumatic chorea - ʻaʻole i kēia manawa.
ʻO ka maʻi keʻala ma nā maʻi maʻi a me nā maʻi.
ʻEha ka maʻi ʻeha (o nā ʻano kumu): ka ʻeha (me nā mea e pili ana i ka hoʻokaʻawale ʻana i ka waiʻona), ka maʻi migraine, ka ʻūhā, neuralgia, lumbago, radicular radicular syndrome, myalgia, arthralgia, algodismenorea.
Me ka lāʻau antiplatelet (e piʻi a hiki i 300 mg / lā): ka maʻi puʻukui coronary, ka ʻike ʻana i nā nui me nā pilikia no ka maʻi puʻuwai coronary, ischemia myocardial painless, palupalu ka theina pectoris, myocardial infarction (e hōʻemi i ka hopena o ka wā mau i ka wā myocardial infarction a me ka make ma hope o myocardial infarction) ʻO ka hōʻeha ʻana i nā kāne, ka hōʻili o ka puʻuwai prosthetic (pale a me ka mālama ʻana i ka thromboembolism), ka ballonary angioplasty a me ke kau ʻana i ka stent (hoʻemi i ka hopena o ka re-stenosis a me ka mālama ʻana i ka stratification kūloko o ka coronary artery), me ka atheros nā maʻi kīlaha o nā corerary artery (ʻo ka maʻi Kawasaki), aortoarteritis (maʻi ʻo Takayasu), nā puʻuwai mākaʻi mitral a me ka fibrillation atrial, prolaps mitral palolo (pale ʻana i ka thromboembolism), embolism aburrent pulmonary, pulmonary infarction, thrombophlebitis akut,
In the immunology clinical and allergology: in unti hoʻonui i nā wa no ka hooliolo ʻana i ka "aspirin" forensitization a me ka hoʻokumu ʻana o ka hoʻomanawanui mau i nā NSAID i nā maʻi me ka "aspirin" asthma a me ka "aspirin triad".
Nā Hoʻohui
Hypersensitivity, erosive a ulcerative lesus o ka gastrointestinal tract (ma ka hopena o ke ake), pehu ka gastrointestinal, "aspirin" triad (kahi hui o ka palaka bronchial, polipose ka waʻeha o ka ihu a me ka paranasal sinuses a intolerance i ka ʻAAA a me nā lāʻau lapaʻau o nā hemusopone hemorropagitis (hemorrhagic hemolele) telangiectasias, hypoprothrombinemia, thrombocytopenia, thrombocytopenic purpura), ʻae ʻana i ka aneurysm aortic, hypertension portal, kakō huawaʻi K, hōʻeha ate / hana ʻole, hapai (I and III trim Stryi), lactation, nele o ka monakō koko-6-posapahate dehydrogenase, na keiki o ka makahiki (i ka 15 makahiki - ka pilikia o ko Reye ka maʻi pale i na keiki me ka hyperthermia ma luna o ke kāʻei kua o ka mea hoʻomaʻi maʻi) .C mālama nui. ʻO ka Hyperuricemia, urate nephrourolithiasis, gout, maʻi o ka ate, ka maʻa gastric a me / a i ʻole ulia duodenal (mōʻaukala), decompensated ka puʻuwai naʻau.
Pehea e hoʻohana ai: dosis a me ke ʻano o ka mālama ʻana
Nā papa pāheʻe: i loko, i hoʻohemo ʻia i mua o kahi wai liʻiliʻi, 400-800 mg 2-3 mau manawa i ka lā (ʻaʻole iʻoi aku ma mua o 6 g). Ma ka hopena o ka rheumatism nui - 100 mg / kg / lā i ka nui o 5-6.
Hoʻololi ʻia nā papa e pili ana i ka ASA i nā inapo ma luna o 325 mg (400-500 mg) i hoʻohana no ka hoʻohana ʻana i kahi lāʻau lapaʻau analgesic a anti-inflammatory, i nā dosis o 50-75-100-300-325 mg i nā pākeke, ʻo ia ka mea ma ka lāʻau antiplatelet.
I loko, me ka ʻeha a me ka maʻi ʻeha, nā pākeke - 0.5-1 g / lā (a hiki i 3 g), i māhele ʻia i 3 mau puhaka. ʻAʻole pono nā lōʻihi o ka mālamaʻana i nā hebedoma 2.
Hoʻopau ʻia nā papa palepona i 100-200 ml o ka wai a lawe mau ʻia ma hope, ma hope o ka ʻai, hoʻokahi kū hoʻokahi - 0.25-1 g, i lawe ʻia he 3-4 mau lā i ka lā. Ka lōʻihi o ka mālama ʻana - mai kahi hoʻokahi i ka papa hoʻokahi papa.
E hoʻomaikaʻi i nā waiwai o ka rheological o ke koko - 0.15-0.25 g / lā no kekahi mau mahina.
Me ka infarction myocardial, me ka pale ʻana i ka lua ma nā mea maʻi ma hope o ka myocardial infarction, 40-325 mg hoʻokahi i ka lā (e like me 160 mg). E like me ka mea e hoʻopili ai i ka hoʻohui platelet - 300-325 mg / lā no ka manawa lōʻihi. Me nā maʻi cerebrovascular ikaika i ka kāne, ka thromboembolism cerebral - 325 mg / lā me ka hoʻonui ikaika i ka nui o 1 g / lā, no ka pale ʻana i ka hoʻi hou ʻana - 125-300 mg / lā. No ka pale ʻana i ka trombosis a i ʻole komo ʻana o ka short aortic, 325 mg kēlā me kēia hola 7 i kahi intranasal gastric tube, a laila 325 mg mau waha he 3 mau lā i ka lā (maʻamau i hoʻohui pū me dipyridamole, kahi i hoʻopau ʻia ma hope o hoʻokahi pule, e hoʻomau i ka mālama mau ʻia me ASA).
Me ka rheumatism ikaika i kuhikuhi ʻia (ʻaʻole i kuhikuhi ʻia i kēia manawa) i loko o kēlā me kēia lā o 5-8 g no nā pākeke a me 100-125 mg / kg no nā ʻōpio (15-18 mau makahiki), ʻo ka nui o ka hoʻohana ʻana he 4-5 mau lā i ka lā. Ma hope o 1-2 mau pule o ka mālama ʻana, hoʻemi ʻia nā keiki i ka dosis i 60-70 mg / kg / lā, hoʻomau ʻia ka mālama ʻana o nā pākeke i nā maʻi like, a hiki i ka 6 wiki ka lōʻihi o ka mālama ʻana. Hoʻololi ʻia ka hoʻopau ʻana ma o nā hebedoma 1-2.
Ka hana lāʻau lapaʻau
Loaʻa i nā NSAID ka hopena anti-inflammatory, analgesic a me nā antipyretic e pili ana i ka pale ʻole o ka hana o COX1 a me COX2, nāna e hoʻoponopono i ka hoʻohuihui o Pg. I ka hopena, ʻaʻole i kūkulu ʻia Pg, hāʻawi i ka hoʻokumu o edema a me hyperalgesia. ʻO ka emi ʻana o nā kiko o Pg (ma mua o E1) i ka waena o ka thermoregulation alakaʻi i kahi kaohi o ke ʻano o ke kino ma muli o ka hoʻonuiʻana o ke kīʻaha koko o ka ʻili a hoʻonui hou i ka lulu.
ʻO ka hopena analgesic e pili ana i ka hana waena a me peripheral.
Hoʻēmi i ka hoʻohui, plathes adhesion a me ka thrombosis e ka pale ʻana i ka synthesis o ka thromboxane A2 i nā platelets. Ke hoʻomau nei ka hopena antiplatelet no 7 mau lā ma hope o hoʻokahi pākahi (ʻoi aʻe ka hoʻolaha ʻia i nā kāne ma mua o nā wahine). Hoʻemi i ka make a me ka hopena o ke kūkulu ʻana i ka infarction myocardial me ka angina paʻa. Loaʻa ia i ka pale mua ʻana o nā maʻi CVD, ināʻo ka infarction myocardial i nā kāne i ʻoi aku he mau makahiki he 40 mau makahiki, a i ka pale ʻana o ka wā hoʻokuʻi myocardial.
I loko o kēlā me kēia lā he 6 g a i ʻole paha, ke pale aku i ka synthesis o prothrombin i loko o ka ate a hoʻonui i ka manawa prothrombin.
Hoʻonui i ka hana fibrinolytic plasma a hōʻemi i ka hoʻoliʻoliʻana o nā huaʻala coagulation hilinaʻi o ka K (II, VII, IX, X). Hoʻonui i nā hoʻopiʻi hemorrhagic i ka wā o ka interventions ka hoʻonui ʻana i ka hopena o ke koko i ka wā o ka maʻi me nā anticoagulants.
Hoʻokomo i ka excretion o ka uric acid (hoʻonāukiuki hou i kona reabsorption i loko o ka renal tubules), akā i nā kiʻekiʻe kiʻekiʻe.
Hoʻopili i ka COX1 i ka mucosa gastric e alakaʻi i ka pale ʻana o ka gastroprotective Pg, hiki iā ia ke alakaʻi i ka ulceration o ka membrane mucous a me ke koko o ka wā. ʻO ka hopena o ka hoʻonāukiuki ʻana i ka membrane waha o ka gastrointestinal tract ke ʻano o nā ʻano wai me nā mea ʻawaʻawa, nā kāpili komo, a me nā ʻano "effervescent" kūikawā o nā papa.
Nā hopena hopena
ʻAno, hōʻeha o ka makemake, gastralgia, ʻehaʻeha, maʻi kūloko (kūloko o ke kino, angioedema, bronchospasm), heʻeha leʻa a me / a hana ʻana i ka maʻi, thrombocytopenia, anemia, leukopenia, Reye syndrome (encephalopathy a me nā maʻi momona ʻalopona me ka hoʻomohala wikiwiki i ka palalike o ka ate) , ka mea i hoʻokumu ʻia i ke kumu o ka mīkini hapten o ka 'aspirin "a me ka" aspirin triad "(kahi hui pūahi o ka bronchial asthma, recurrent polyposis o ka ihu a me ka paranasal sinuses a me ka hemahema o ka ASA a me nā lāʻau lapaʻau o ka hōʻike pyrazolone).
Me ka lōʻihi o ka hoʻohana ʻana - ka dizziness, headache, utuka, erosive a me ulcerative lesi o ka gastrointestinal tract, hypocoagulation, pehu (e komo ana i ka gastrointestinal tract), ʻike hoʻopiʻi, lohe ʻeha, tinnitus, bronchospasm, interstitial nephritis, hoʻonui prerenal azotemia creatinine blood and hypercalcemia, papillary necrosis, acute renal failed, nephrotic syndrome, aseptic meningitis, hoʻonui hōʻailona o ka puʻuwai naʻau, edema, hoʻonui i nā hana o ka "hepatic" transaminases. Overdose. ʻO nā ʻōpū (hoʻokahi ka wai o nā haʻahaʻa ma mua o 150 mg / kg - ke nānā nei i ka maʻi o ka huehue, 150-300 mg / kg - moderole, ʻoi aku ma mua o 300 mg / kg - ikaika): salicylism syndrome (nausea, hoʻopuka, tinnitus, blurred vision, dizziness, koʻikoʻi hōʻeha, ka maʻi maʻamau, ke kuni - ka hōʻailona prognostic maikaʻi i nā pākeke). ʻO ka laʻala huehue - hyperventilation o ka māmā o ka puka kumu, ke ea alkalosis, metabolic acidosis, ʻike papau, nā ʻūlū, hāʻule, hoʻopulapula, anuria, koko. I ka wā mua, ʻo ka hyperventilation koʻikoʻi o nā māmā e alakaʻi i ka alkalosis o ke ea - ka pōkole o ka hanu, ka puʻu, cyanosis, ke anuanu, ka palu palaka, me ka nui o ka hoʻonaninani, nā māpana o ka ea a me ka wehe i ka ohi?
I ka lāʻau nui o ka lolo, ʻaihue ka pilina o ka plasma me ka paʻakikī o ka lilo. Loaʻa ka pilikia nui loa o ka hoʻomohala ʻana i ka hoʻōla luhi i ka poʻe ʻelemakule me ka nui o kahi ʻoi aku o 100 mg / kg / lā no nā lā he nui. I nā keiki a me nā poʻe maʻi maʻi, ʻaʻole e ʻike mau ʻia nā hōʻailona mua o ka salicylism, no laila, e kuhikuhi ʻia e hoʻopaʻa i ka manawa maʻamau i ka neʻe ʻana o ka salicylates i ke koko: he pae aʻe ma mua o 70 mg% e hōʻike ana i ka meaʻawaʻawa a maʻalahi paha, ma mua o 100 mg% - koʻikoʻi nui, prognostically hikiʻole. No ka lāʻau ʻawaʻawa māmā, pono ʻia ka hale hoʻomaha ma 24 mau hola.
Hoʻomaʻamaʻa: hoʻonāukiuki o ka luaʻi, ka koho ʻana i ka uluhua a me ka laxatives, ka hoʻomau mau ʻana i ka nānā ʻana o ka BOC a me ka hoʻoponoponoʻana i nā electrolyte, hilinaʻi i ka ʻano o ka metabolism - ka hoʻokumu ʻana o ka sodium bicarbonate, sodium citrate a i ʻole sodium lactate. Hoʻonui ka nui o ka alkalinity i ka hoʻopau ʻana o ka ASA ma muli o ka alkalization o ka urine. Hōʻike ʻia ka alkalization urine no ka salicylates ma luna o 40 mg% a hoʻolako ʻia e ka iv infusion o ka sodium bicarbonate (88 mEq ma 1 l o kahi hopena o ka dextrose 5%, ma ka pae he 10-15 ml / h / kg), ka hoʻihoʻi hou o ka bcc, a me ka hoʻolake o ka diuresis i loaʻa i ka hoʻokumu ʻana o ka sodium bicarbonate ma nā lemea like a me nā hoʻopiha, kahi e mau ʻia ana nā manawa 2-3. Hoʻohana pono ʻia ka makaʻala ma nā mea maʻi ma waena o nā maʻi a hiki i nā maʻi infusion fluid hiki ke alakaʻi i ka edema pulmonary. ʻAʻole hoʻohana ʻia ka hoʻohana ʻana o ka acetazolamide no ka alkalization o ka urine (hiki iā ia ke hoʻoulu i ka acidemia a hoʻonui i ka hopena o nā salicylates. Hōʻike ʻia ka Hemodialysis no nā salicylates o ʻoi aku ma mua o 100-130 mg%, i loko o nā mea maʻi me ka hoʻomāino kino - 40 mg% a emi ʻole inā i hōʻike ʻia (refractory acidosis, holomua holomua, hōʻino koʻikoʻi i ka pūnaehana waena, pulmonary edema a me nā hana ʻole ʻole). Me ka edema pulmonary, hoʻopili ʻia ka pono o ka mīkini me ka oxygen.
Nā ʻōlelo kikoʻī
ʻAʻole lōʻihi ka lōʻihi o ka mālama ʻana (me ke kūkā ʻana i ke kauka) 7 mau lā i ka wā i kuhikuhi ʻia ai he lāʻau lapaʻau analgesic a ʻoi aku i nā lā 3 mau lā he antipyretic.
I kēia manawa, ʻo ka hoʻohana ʻana o ASA he lāʻau lapaʻau anti-inflammatory i kēlā me kēia lā o 5-8 g i kaupalena ʻia ma muli o ka nui o ka hopena o ka hopena mai ka gastrointestinal tract (NSAID gastropathy).
Ma mua o ka hōʻemi ʻana, e hōʻemi i ke koko i ka wā o ka hōʻemi ʻana a ma ka wā postoperative, pono ʻoe e hoʻokaʻawale i ka lawe ʻana i nā salicylates no nā lā 5-7 a hoʻolaha i ke kauka.
I ka wā lōʻihi, pono ke hōʻike i kahi hōʻike koko ākea a me ka hoʻāʻo ʻana i ka toto occult fecal.
ʻAʻole pono nā keiki i kuhikuhi i nā lāʻau lapaʻau e pili ana i ka ASA, no ka mea inā kahi maʻi maʻi, hiki iā lākou ke hoʻonui i ka hopena o ka hopena o Reye. Hoʻomaʻamaʻa i nā ʻōuli o Reye o ka maʻi me ka hoʻopuni lōʻihi, ka encephalopathy aʻai, a me ka nui i hoʻonui ʻia.
ʻO ke koho ʻana o nā papa ma hope o ka papaʻaina, kā lākou wili piha ʻana, ka hoʻohana ʻana i nā papa me nā poʻohiwi a i ʻole ʻia hoʻi me ka pani ʻana o ka enteric kūikawā, me ka hoʻohana like ʻana i nā lāʻau lapaʻau e hoʻokaʻawale i ke ʻano o ka wai o gastric, hōʻemi i ka hopena o ka irritating ma ka digestive tract.
Loaʻa ia i kahi hopena teratogenic, i ka wā i hoʻohana ʻia ma ka trimester mua, alakaʻi ia i ka hoʻomohala ʻana i ka palate o luna, i ka kolu o ka ʻekolu ka mea e hoʻoulu ai i ka hana hana (inhibition o Pg synthesis), ka hana mua o ka ductus arteriosus i loko o ka wā o ka fetus, pulmonary vascular hyperplasia a me hypertension i ka pulmonary circulation. Hoʻohui ʻia ia i ka umauma umauma, kahi e hoʻonui ai i ke kahe o ke koko i loko o kahi keiki ma muli o ka hana platelet impaired.
ʻO ASA i loko o nā poho liʻiliʻi e hōʻemi ana i ka hoʻonuiʻana i ka waikina uric mai ke kino, hiki iā ia ke alakaʻi i ka hoʻouka ʻana o kahi huakaʻi hōʻeha o ka gout i nā mea maʻi hiki.
I ka wā e pono ai ka mālama ʻana e pale aku i ka ethanol.
Hoʻohui
Hoʻonui ia i ka mea paʻa o ka methotrexate, hoʻoemi i ka hoʻomaʻemaʻe kino, nā hopena o nā NSAIDs, nā narcotic analgesics, nā hopena hypoglycemic oral, reserpine, heparin, indirect anticoagulants, thrombolytics a me platelet aggregation inhibitors, sulfonamides (me ka hopena o ka co-trimox 3, hoʻemi i ka co-trimox) nā uricosuric lāʻau (benzbromarone, sulfinpyrazone), nā lāʻau antihypertensive, diuretics (spironolactone, furosemide).
ʻO GCS, ethanol a me nā huaʻai e pili ana i ka ethanol ka hoʻonui ʻana i ka hopena hōʻino i ka mucosa gastrointestinal, hoʻonui i ka nui o ke koko o ka gastrointestinal.
Hoʻonui nā kuʻi o ka digoxin, barbiturates, a me nā paʻakai Li + i ka plasma.
Nā antacids i loaʻa Mg2 + a me Al3 + e hoʻolohi hoʻolohi i nā mea o ke kauʻana o ASA.
Hoʻonui ka lāʻau Myelotoxic i nā hōʻike o ka hematotoxicity o ka lāʻau.
ʻO ka hoʻohanaʻana i ka acetylsalicylic acid MS i ka wā o ka wā hāpai a me ka lactation
Contectedicated i ka I and III trimesters o ka hapai. I ka trimester II no ka hapai, hiki i ke komo ʻana kahi mea e like me ke kuhikuhi ʻana i ka nui.
Loaʻa ia i kahi hopena teratogenic: i ka wā i hoʻohana ʻia ma ka trimester mua, alakaʻi ia i ka hoʻomohala ʻana o ka palate o luna, i ka kolu o ka lāʻala ia e hana ai i ka hana o ka hana (inhibition of prostaglandin synthesis), ka wā o ka pani o ka ductus arteriosus i loko o ka pūpū, ka pulupulu o ka hyperplasia pulima a me ke hypertension i loko o ka pulmonary.
Hoʻopili ka Acetylsalicylic acid i ka waiū umauma, kahi e hoʻonui ai i ka hiki o ke kahe koko i loko o kahi keiki ma muli o ke ʻano o ke kumu platelet, no laila, ʻaʻole pono ka makuahine e hoʻohana i ka acetylsalicylic acid i ka wā lactation.
Nā NSAID. He ia anti-inflammatory, analgesic a me nā antipyretic hopena, a ke pale aku nei i ka platelet aggregation. Hoʻopili ka hana o ka hana me ka pale ʻana i ka hana COX - ka mea nui o ka hoʻoneʻe o ka metabolism o ka acid arachidonic, kahi mea he mea i ka mua o ka prostaglandins, e hana nui ana i ka pathogenesis o ka mumū, ʻeha a me nā maʻi. ʻO ka emi ʻana o nā kiko o ka prostaglandins (ʻoi loa ka E 1) i ka waena o ka thermoregulation alakaʻi i kahi kaohi o ke ana o ke kino ma muli o ka hoʻonuiʻana o nā kahe koko o ka ʻili a me ka hoʻonui nui ʻana. ʻO ka hopena analgesic e pili ana i ka hana waena a me peripheral. Hoʻēmi i ka hoʻohui, platelet adhesion a me ka thrombosis e ka pale ʻana i ke kāpili ʻana o ka thromboxane A 2 i nā platelets.
Hoʻemi ʻia ka make ma ka hopena o ka hoʻomohala ʻana i ka infarction myocardial me ka angina pectoris kūpaʻa. E mālama pono i ka pale mua ʻana o nā maʻi o ka ʻōnaehana cardiovascular a me ka pale ʻana i ka lua o ka infarction myocardial. I loko o kēlā me kēia lā he 6 g a i ʻole paha, ke pale aku i ka synthesis o prothrombin i loko o ka ate a hoʻonui i ka manawa prothrombin. Hoʻonui i ka hana fibrinolytic plasma a hōʻemi i ka hoʻoliʻoliʻana o nā huaʻala coagulation hilinaʻi o ka K (II, VII, IX, X). Hoʻonui i nā hoʻopiʻi hemorrhagic i ka wā o ka interventions ka hoʻonui ʻana i ka hopena o ke koko i ka wā o ka maʻi me nā anticoagulants. Hoʻokomo i ka excretion o ka uric acid (hoʻonāukiuki hou i kona reabsorption i loko o ka renal tubules), akā i nā kiʻekiʻe kiʻekiʻe. Hoʻokiʻoki i ka COX-1 i ka mucosa gastric e alakaʻi i ka pale ʻana o nā prostaglandins gastroprotective, hiki iā ia ke alakaʻi i ka ulceration o ka membrane mucous a me ke koko hoʻoneʻe ma hope.
ʻO kekahi mau ʻike
ʻO ka lāʻau lapaʻau ka mea hoʻoneʻe e hoʻopau i nā kaʻina hana.ʻO ka mea hoʻohana nui a ka lāʻau lapaʻau he aspirin, a he nui kona mau hopena. ʻO ka mea nui ka puna wai i huna ʻia mai ka papalina keʻokeʻo. Ua hoʻohana ʻia ke ʻano o ka lāʻau i ke ʻano lāʻau lapaʻau i nā makahiki he mau makahiki i hala aku nei. I 1838, i Italia, ʻo ka mea hoʻokalakupuaʻo Rafael Piria i synthesized salicylic acid. Akā i ka hoʻomaka ʻana o ʻAukake 1897 i Kelemānia, ua hoʻohana kahi mea noiʻi ma Bayer AG i ke kaʻina acetylation i ka waikō, no laila e hoʻohālikelike ana i ka acetylsalicylic acid. ʻO Felix Hoffman kona inoa. Akā no ka inoa o ke kālepa ʻo Aspirin ka mea Kelemānia.
Ka hoʻonohonoho ʻana a me ke ʻano o ka hoʻokuʻu ʻana
ʻO ka pūnaehana o ka lāʻau lapaʻau e hoʻokomo i nā ʻāpana:
- acetylsalicylic acid
- kalaka kākāʻau
- ka leʻaleʻa talcum
- waiū waiū
- polyvinylpyrrolidone haʻahaʻa loa,
- lāʻau kūmole.
Loaʻa ka huahana i nā papa keʻokeʻo me nā kihi beveled a me kahi ʻano elliptical. Ma kekahi ʻaoʻao o ka uluna kahi hōʻailona hoʻokaʻawale. Hoʻopili ʻia nā paila ma nā palaha ʻelua, ʻo kēlā me kēia ʻāpana. Aia nā poli i nā pahu kāleka me nā kauoha no ka hoʻohana.
ʻO nā waiwai Pharmacological
Hoʻohana ʻia ka hoʻohana ʻana o ka acetylsalicylic acid MS no ka ʻeha, kehi, ka ʻōpala. He hopena maikaʻi ka maikaʻi, no ka mea he COX inhibitor. Hoʻemi ka mea i ka nui o nā enzyme, e pale ai i ka hoʻokumu ʻana o nā momona momona polyunsaturated, ʻo ia hoʻi, e kōkua i ka hoʻomohala ʻana i ka huehue. Pēlā nō hoʻi, hoʻolilo ka aspirin i nā capillaries i liʻiliʻi loa i ka neʻe ʻia, hōʻemi ʻia ka hana o nā enzyme e kuleana ai i ka hoʻopau ʻana i ka mucopolysaccharides waikawa, a me ka hoʻoluhi ʻana i nā hiʻohiʻona o ka ATP.
Hoʻopili maikaʻi loa ka waiwai i ke kino. Loaʻa ka ʻoiʻoi loa kiʻekiʻe ma hope o 120 mau minuke. Holo koke ia i ka kino o ke kino, komo i loko o ka iwi iwi, kaila cerebrospinal, a me nā mea hoʻi. I hoʻopili ʻia me ka urine i loko o 60% o ka nui i loaʻa. ʻO ka hapa hapalua he hapa loa he 2 mau hola, ʻoiai ka lōʻihi o ka manawa i hiki i 30 mau hola.
ʻO kahi hōʻailona no ka lawe ʻana i ka hopena hiki ke lilo i papa inoa hoihoi o nā maʻi, me ka:
- ka hana ʻana i nā ʻano ʻeha like ʻole (ke poʻo, ka niho, ka ʻōpū a me ka iwi, hoʻopili)
- nā mea hoʻonāukiuki o ke kaila wela o ke kino (ARVI, ARI a me ka mumū, loaʻa ke ʻano infectious),
- nā hana maikaʻi ʻole i ka hana o ka ʻōnaehana cardiovascular (ischemia, puʻuwai puʻuwai, hoʻopiʻi i ka naʻau, hōʻoki ʻia i loko o ka puʻuwai puʻuwai).
Eia kekahi, hoʻohālike me ka lāʻau lapaʻau me ka hōʻeha i ka wā o ka haʻu ʻana a me nā hōʻeha nasopharyngeal.
Nā ʻano hana a me nā hiʻohiʻona
Ua kuhikuhi ʻia ʻo Aspirin no nā pākeke a me nā keiki i kēia mau iho mea:
- mai 6 mau makahiki, hapalua papa pākeke i ka manawa.
- mai 12 mau makahiki a ʻo nā mākua a i ʻole a i ʻole ka ʻāpana āpau.
Lawe pinepine ka lāʻau i ka manawa 3-4 i loko o 24 mau hola, me kahi manawa o 4 mau hola. Pono e kau ka nui o kēlā me kēia lā nui no kahi pākeke 3 mika, ʻo ia hoʻi, 6 papa, kahi ʻae ʻia hoʻokahi o ka waiwai i loko o ka 1 gram. No ka hoʻopauʻana i nā maʻi vascular, e ʻae ʻia e hoʻopau mai 0.75 i 3 mau grama i kēlā me kēia lā.
Pono e holoi ʻia kēlā me kēia paila me ka nui o ka waiū a i ʻole ka wai (mineral, distilled). I kēia hihia, pono ke kuhikuhi ʻia o ka hoʻohana ʻana ma hope o ka ʻai ʻana.
Inā hoʻohana ʻia ka lāʻau lapaʻau e hōʻemi i ka mahana, ʻo ka manawa o kona hoʻohana ʻana me ka ʻole o ka mālama ʻana e ke kauka ʻaʻole iʻoi aku i nā lā ʻekolu. Inā he kumu a hōʻeha paha ke kumu o ka lāʻau, hiki iā ʻoe ke hoʻonui i kēia manawa i hoʻokahi pule.
ʻO nā mea mālama palekana
No ka hoʻonuiʻana i ka pono o ka Acetylsalicylic Acid MS, he mea nui e ukali i nā aʻaluhi maʻalahi:
- Mai hoʻokō i ka aspirin ma mua o kahi hana i hoʻonohonoho ʻia. Hoʻonui ka hāmeʻa i ka pehu, no ka mea hiki ke hoʻopau ʻia ma mua o ka wehe ʻana o ka niho. ʻOi aku ka maikaʻi e hāʻawi i kahi waikahi i hoʻokahi pule ma mua o ka hoʻokō ʻana.
- Hoʻonui ka hāmeʻa i nā hōʻike hōʻike gouty.
- Manea ʻia e inu i nā pōpoki me ka wai nūhou wale nō i hoʻomaikaʻi ʻia, no ka mea e hoʻomaikaʻi ana i ko lākou komo ʻana.
- ʻAʻole pono ʻoe e lawe i ka waiwai ma ka ʻōpū ʻole, i ʻole e hoʻonāukiuki i ka hoʻokumu ʻana o kahi ulia.
I ka wā hāpai
No ka mea hiki i ka acetylsalicylic acid MS ke komo i ka papa o ka placental, ʻaʻole pāpā ia i kēia lāʻau lapaʻau i kēlā me kēia manawa i ka wā hāpai. Hoʻopilikia ka huahana ikaika i ke keiki a hoʻonāukiuki i ka lohi, ke kāohi ʻana i nā ʻalihi a me nā moku pulmonary, me ka hoʻokaʻawale hoʻi i ka pala o luna. Ua hūnā ʻia ʻo Aspirin i ke kaʻina o ka umauma, kahi e hoʻonāukiuki ai i ke koko ma kahi keiki hou. Inā ʻike ʻia ka wahine hāpai i ka wā o ka mālama ʻana me kēia lāʻau lapaʻau, pono ia e pani koke e lawe iā ia a hiki i ka hopena nui o ka ʻōpū.
Nā hopena hopena
ʻO ke ʻano o nā hana pākuʻi, hiki i nā hopena ke hiki mai ma muli o ka hoʻohana ʻana o ka acetylsalicylic acid MS:
- ka hoʻohaʻahaʻa ʻōpū, ʻeha o ka ʻōpū, ka puʻuwai, hōʻeha, ka ʻōpū, ka luaʻi,
- ka tinnitus, ʻeha ma ke poʻo, ka mea i hoʻohaʻahaʻa i ka acuity ʻike a me ka lohe,
- mahuahua i nā pilikia i ka hana o ka pūnaehana naʻau a me nā kīʻaha koko,
- hana hewa ʻana o ka pūpū a me nā pōpilikia, nephritis,
- ka ʻōpū o ke ʻāʻī a me ka ihu, ka ʻāʻī a wī ma ka ʻili.
Inā ʻike ʻoe i hoʻokahi a i ʻole paha o kēia mau ʻōuli, pono e nīnau koke i ke kauka a hoʻomaʻamaʻa hou i kahi keʻena haukapila.
Ke keu
Me ke kumu, ua hoʻokaʻawale ʻia kahi overdose o ka aspirin i ʻekolu mau ʻāpana, kēlā me kēia, aia ke ʻano o kona ʻano o nā hōʻailona:
- Waimea. He lua, he ʻeha, ka dizziness, ka noʻonoʻo vague. E lilo ana ka mea maʻalahi i ka mea maʻi i hōʻemi i ka nui o nā lāʻau lapaʻau i hoʻopau ʻia.
- He kaumaha. Hōʻeu, ka coma, hoʻemi nui i ke kaomi, ka hoʻopiʻi ʻana a i ʻole hoʻi me ka hoʻāʻo ʻole e hoʻoulu i ka ea i loko o ke ake, ke piʻi ʻana hoʻi ka nui o ka glucose a me nā hāmeʻe i loko o ke koko, hiki ke hoʻopau ʻia ka pale kaulike-base.
- Ka Hoola Ua hoʻoholo ʻia e ka nui o ka salicylic acid i ke koko. Inā ʻike ʻia ka 0.7-1 g o ka acetylsalicylic acid no ka kilokena o ke kaupaona ʻana, hana ʻia kahi maʻi hoʻomaha wikiwiki.
ʻO ka maʻamau, hoʻāla ʻia ka loiloi, hemodialysis, hoʻoulu ʻia i nā wai, hoʻopau ʻia nā hōʻailona ʻānō no ka mālama ʻana. Pono ʻia ka pono ma waena.
Nā kūlana mālama
Pono e mālama i ka Acetylsalicylic acid MS ma kahi anu a maloʻo kahi e piʻi ai ka mahana ma luna o 25 degere Celsius. I kēia hihia, pono e hōʻike ka pā i ka radiation ultraviolet, a pono pono e hūnā ʻia nā keiki. ʻO 48 mau malama ka ola o ka papa o nā papa, e hoʻomaka ana mai ka lā i hōʻike ʻia ma ka ʻaoʻao. ʻAʻole pāpā ʻia e hoʻohana i ka huahana ma hope o kēia manawa.
I waena o nā lāʻau lapaʻau e loaʻa ai ka like me ka like pū me nā mea nui:
Eia naʻe, nā koi no ka lāʻau lapaʻau, ʻaʻohe pono o ka lāʻau lapaʻau ponoʻī iho, akā e wehewehe i ka mea lapaʻau i ka pololei o ke koho ʻana i kahi analogue, e pili ana i ka mōʻaukala pilikino.
Ke laikini laikini LO-77-02-010329 i a Iune 18, 2019
Inoa Kūʻai ʻole honua
Ka waikawa Acetylsalicylic (Acetylsalicylic acid).
ʻO Acetylsalicylic acid MS (medisorb) kahi mea hoʻohana non-steroidal anti-inflammatory lāʻau.
N02BA Salicylic acid a me nā mea pae palapala.
Lapaʻau lāʻau
Hoʻokomo ʻia ka holopapa mai ka ʻōpū ma loko piha. Hāʻawi ka ASA i nā ʻōnaehana ma kahi o ka anion o ka waikawa salicylic. Hoʻomoʻa ʻia ka lāʻau i ka plasma koko wale nō, akā, i loko o nā ʻiʻo o ka iwi-cartilage, a ma nā ʻano o synovial (inter-articular).
Hoʻokomo ʻia ka holopapa mai ka ʻōpū ma loko piha.
Mai ke kino, excreted i ka lāʻau i ke ʻano o ka metabolites me ka hoʻohana ʻana i ka ʻōnaehana urinary. Ka helu wikiwiki - mai 2 a 30 mau hola, hilinaʻi paha i ke ʻano lāʻau.
He aha ka mea e kōkua ai
He laulā ākea ka ASA o ka hana, ka hoʻoneʻe ʻana i nā kaʻina ʻeha a e hōʻemi i ka ʻeha. Eia kekahi, he waiwai ʻokoʻa ka lula o ka waikahe, kahi e pono ai i ka mālama a me ka pale ʻana o nā maʻi cardiovascular. I kēia mea, hoʻohana ʻia ka lāʻau lapaʻau i loko o nā hihia penei:
- mahuahua i ka nui o ke kino i ka wā o nā kaʻina hana a me nā maʻi maʻi maʻi,
- ka pale ʻana i nā koko koko a me ka embolism, pākaʻi hoʻoneʻe, nā varicose veins, thrombosis,
- nā ʻeha o nā kumu: ke kāne, ka hōʻeha, ka ʻeha, ka ʻeha, a me nā mea ʻē aʻe.
- ma ka ʻoihana ke hoʻohana nei au i kahi hoʻonāukiuki e hōʻoluʻolu i ke kuni a me ka ʻeha,
- cardiovascular pathologies: ischemia, arrhythmias, prevention of the recurrent myocardial infarction, stroke, Kawasaki disease, heart failed.
Hoʻohana ʻia ka lāʻau lapaʻau no ischemia.
Hoʻohana ʻia ka lāʻau lapaʻau no nā veins varicose.
Hoʻohana ʻia ka lāʻau lapaʻau i nā kiʻekiʻe kiʻekiʻe.
Hiki i kahi papa pākahi ke hoʻohaʻahaʻa i ka pāhana a hoʻomaha paha i kahi maʻi ʻehaʻeha. I loko o nā ala pilikia, no ka pale ʻana a i ka mālama ʻana, inu ka acetylsalicylic acid me kahi papa e hoʻoholo ai ke kauka i ka mea i kau ʻia.
Pehea e lawe ai i ka acetylsalicylic acid MS
Lawe ʻia ka lāʻau ma mua o ka ʻai a holoi ʻia me nā wai maʻemaʻe. Me kahi pākahi hoʻokahi, ua hoʻohana ʻia ka 0,5 mg o ka lāʻau (1 papa). Hiki ke hoʻohana hou ke hoʻohana hou ma mua o 4 mau hola. ʻAʻole pono nā dosis o kēlā me kēia lā e 6 papa.
I ka hoʻomaʻamaʻa paʻakikī ʻana i nā maʻi o nā maʻi a i ʻole nā maʻi paha, ua kuhikuhi ʻia ka ASA i loko o kahi waihona o 1 mg o ka lāʻau (2 papa) ʻekolu mau manawa o ka lā.
ʻAʻoleʻoi aku ka lōʻihi o ka lōʻihi o ka mālamaʻana i nā lā 7 me ka haʻalulu maʻamau a ʻaʻole iʻoi aku ma mua o 3 me kahi kahe o ke ana. Ke lawe nei i ka lāʻau lapaʻau, mea nui ka makaʻala ʻana i kahi ʻai olakino.
Mai ka pūnaehana urinary
ʻO ka hoʻomohala ʻana o ka hana ʻole i ka renal, ka pinepine o ka urination, nephrotic syndrome, ka ulu ʻana o ka nephritis ikaika loa.
Hiki i kahi hopena alia ke hopena ma muli o ka hoʻomalokaʻana i nā hana o ka aʻina a i ʻole hoʻokele kūpono ʻana o ka lāʻau. Hōʻike ʻia ka pathology e ka ʻāʻī o ka ʻili, kaʻili. I kekahi mau pilikia, pilikia ka hanu e pili ana me ka huehue ʻana o ka pharynx.
Koha i na keiki
ʻAʻole kuhikuhi nā keiki ma lalo o 15 mau makahiki i ka papa ASA MS ma muli o nā hopena koʻikoʻi o nā hopena ʻaoʻao. ʻO nā mea he okoa nā hopena koʻikoʻi o ka wela nui, kahi e mālama ai ke kauka i ka "triad" (Aspirin, Analgin a No-Shpu) i ka ulia pōpilikia. ʻAʻohe hoʻomaʻamaʻa hoʻomaʻamaʻa ʻole. Ma ka hoʻomau mau nei, ua āohi ʻia ʻo ASA i nā keiki.
Hoʻohana i ka wā hāpai a me ka lactation
ʻAʻole ia e hāʻawi i ka lāʻau i ka wā hāpai, ʻoi aku hoʻi i ka trimester mua, i ka wā i hoʻomoe ai ka pūpū. I ka lua o ka trimester, hiki iā ʻoe ke hoʻohana i ka lāʻau lapaʻau ma nā liʻiliʻi liʻiliʻi, inā uaʻoi aku ka hopena i manaʻo ʻia. No ka mea piha ka lāʻau i ke koko a me nā mea āpau o ke kino, i ka wā lactation he pōʻino loa ia e lawe, no laila ʻaʻole e hōʻino i ke keiki.
Ke noi no ka hana renal impaired
I ka wā hana ʻole ʻole, ʻaʻole hoʻohana ʻia ASA ma muli o ka hiki ʻole ke kāpae i nā huahana hope loa. Ma muli o kēia, hoʻonāukiuki ka metabolism a ke emi nei ka hana a aneane āpau a me nā ʻōnaehana.
I ka wā ʻole o ka noho ʻana, ʻaʻole i hoʻohana ʻia ʻo ASA ma muli o ka hiki ʻole ke hoʻoneʻe i nā huahana hope loa.
Hoʻolaha ka waipuna
ʻO nā mea inu wai hoʻohālikelike i ka ethanol, ka mea i ka wā e hoʻopili ai me ASA i hoʻonui i ka nui o ka hoʻokaʻeha o kaʻeha, ke hoʻomohala ʻana i ka gastritis a i nā ʻūhā a me nā mea hoʻowalewale.
I waena o nā lāʻau lapaʻau o kahi hana like, hiki ke hoʻomaopopo ʻia kēia:
- Koi Kapua,
- Aspirin Cardio,
- Cardiomagnyl.
I waena o nā lāʻau o nā hana like, hiki ke hoʻomaopopo ʻia ʻo Cardiomagnyl.
I waena o nā lāʻau o nā hana like, hiki ke hoʻomaopopo ʻia
I waena o nā lāʻau lapaʻau o ka hana like, ʻo Thrombo Ass.
He mea nui e hoʻomanaʻo e pili ana ka loiloi me ka ʻole o ka ʻōlelo ʻana i ka mea loea i hiki ke hōʻino i ka olakino, no laila e kamaʻilio ʻoe i kāu kauka ma mua o ka hoʻololi ʻana i kāu lāʻau lapaʻau.
Mea hana
CJSC Medisorb, Lūkia.
ʻO Marina Sergeevna, 48 makahiki, Oryol
Ua hala wau i ka ASA i mau makahiki he nui e hoʻokaʻawale i ke koko. Ua ʻōlelo ʻia ʻo Cardiomagnyl ma mua, akā i ka ʻimi ʻana no nā analogue, ua ʻōlelo mai ke kauka iaʻu e hoʻohana i ka lāʻau lapaʻau Medisorb. ʻO kahi hoʻoponopono maikaʻi loa, lawe koʻikoʻi wau e like me ke kākā, ʻaʻohe hopena hopena.
Ivan Karlovich, 37 makahiki, Yeysk
No ka arthrosis hui ʻia, ua kuhikuhi ʻia kēia mau lāʻau. ʻAʻole hiki iaʻu ke ʻōlelo aku ua pau nā mea āpau i ka hoʻopau koke ʻana, akā ua hala ke kaumaha no kekahi manawa. Kōkua wale ka ASA me ka mālama paʻakikī.