Pehea e hoʻohana ai i ka lāʻau lapaʻau Tsiprolet 500?
ʻO ka lāʻau lapaʻau "Tsiprolet 500" e pili ana i ka lāʻau lapaʻau a hoʻokomo ʻia i loko o ka hui o nā fluoroquinolones. Ua manaʻo ia no ka mālama ʻana i nā ala mālamuhī hopohopo e hōʻoli ai i ka microflora pili i ka lāʻau. He hana kiʻekiʻe a wikiwiki ka pono.
Ka hopena hopena o ka lāʻau lapaʻau "Tsiprolet 500"
Hoʻopili ka lāʻau lapaʻau me ka hana hou o ka DNA huakini, a laila hōʻino ko lākou hoʻokaʻawale a me ka ulu. ʻOi aku ka maikaʻi o ka lāʻau lapaʻau no ka mālama ʻana i nā maʻi e hōʻoli ai i ka maʻi bacteria-kino (salmonella, E. coli, Klebsiella, Shigella). Hoʻopilikia ka lāʻau lapaʻau i nā microorganisms kūpono i nā lāʻau (streptococci, staphylococci). Hoʻohana ʻia ka mea hana e mālama i nā pathologies ma muli o ka mana o ke microbes intracellular (chlamydia, tuberculous mycobacteria). ʻO ka lāʻau maikaʻi hoʻi no ka mālama ʻana i nā maʻi i hoʻoiho ʻia e Pseudomonas aeruginosa. Hoʻokumu ʻia ka Ciprolet 500 i ke ʻano o nā papa me ka waihona hua e hoʻōla ai i nā mea he 0,5 mauʻu. Aia kekahi mau pū me kahi puʻupuʻu liʻiliʻi o kēia mea (250 mg). Hoʻokuʻu a me ke kūleʻa no ka infusion. ʻO nā analogues o ka lāʻau lapaʻau ka Siflox, Ciprinol, Ciprofloxacin.
Nā hōʻailona no ka hoʻohana ʻana
Hoʻohana ʻia ka lāʻau lapaʻau "Tsiprolet 500" e mālama i nā maʻi o ka pepeiao, ka ʻāʻī, ka ihu, a me nā mea hanu. Ua hōʻike ʻia kona hoʻohana ʻana i ka pneumonia i hōʻā ʻia e staphylococci, hemophilic bacilli, legionella, Klebsiella, enterobacter. Me ke kōkua o ka mea lapaʻau, mālama ʻia nā maʻi o ka membula, ka pāpā a me ke ahi, nā ʻāpana ʻimi ʻana, ka ʻili, nā maka, nā palupalu, nā hua genitourinary, e kākoʻo ana i ka ʻōnaehana musculoskeletal, a me nā pelvis liʻiliʻi. Lawe i nā peni no sepsis, peritonitis, prostatitis, pelvioperitonitis, adnexitis.
ʻO nā hiʻohiʻona o ka lāʻau paʻi "Tsiprolet 500"
Ua papa ʻia ia e hoʻohana i ka lāʻau lapaʻau i ka wā hapai, nā keiki ma lalo o nā makahiki he nui loa, nā makuahine hānai, me ka hypersensitivity. Hoʻohana lākou i ka lāʻau lapaʻau me ka mālama ʻana i nā hihia o ka pilikia o ka lolo, ka hiki ʻole o ka lolo, a me ka ʻāʻī, ka maʻi noʻonoʻo, a me ka epilepsy. ʻAʻole hiki ke hāʻawi i kahi lāʻau lapaʻau i ka poʻe maʻi.
Nā hopena hopena
Ke hoʻohana nei i ka lāʻau lapaʻau, hiki ke loaʻa nā hopena maikaʻiʻole e like me ka psychosis, diplopia, hallucinations, tinnitus, he ʻōpū o ka ʻōpū, hoʻonui i ka hoʻoikaika i ka intracranial, ʻeha, a me ka insomnia. Hoʻomaʻo nā kino Digestive i ka hoʻohana ʻana i nā papa me ka maʻi palupalu, lemela, hoʻoluhi i ka makemake nui, ka luaʻi, ka ʻeha o ka ʻōpū a me ka ʻōpū. I ka wā mālama, hypotension, tachycardia, jaundice cholestatic, ʻāʻī a me ka ʻeha o ka naʻau, ke ʻano o ka anaphylactic, urticaria, ʻulaʻula a me ka ʻeha e hoʻomohala.
"Tsiprolet 500": kuhikuhi i ka hoʻohana
Lawe ʻia nā papa maʻa wale ma mua o ka ʻai, holoi ʻia me ka nui o ka wai. Hoʻokumu ka dosis i ka maʻa o ka pathology, ʻo ka makahiki o ka mea maʻi a me kona paona kino. No ka mālamaʻana i ka gonorrhea, lawe iā 1 papa o Kaʻuolet (500 mg). Hoʻohana ʻia ka nui o ka leo no ka mālama ʻana i nā hōʻeha pilikia o ka ʻāpana urinary, prostatitis, gnecological abnormalities, osteomyelitis, enterocolitis.
E hoʻokuʻu i ke ʻano a me ka ʻano
Loaʻa ʻo Ciprolet i loko o kēia mauʻano hoʻohālikelike:
- ʻO nā papa ʻoniʻoni kiʻoniʻoni: biconvex, kahi pōʻai, me kahi pālahalaha ma nā ʻaoʻao ʻelua, aneane keʻokeʻo a ʻele paha paha, kokoke like ke keʻokeʻo a ʻūhā paha ke kiki (10 mau ʻāpana i nā palaka, 1 a i ʻole 2 mau blisters ma ka pūlima pepa).
- ʻO ka hopena no ka infusion: aniani ka malamalama, ke aniani, ka aniani (100 ml kēlā me kēia i loko o nā pahu o ka polyethylene haʻahaʻa haʻahaʻa, 1 pahu i loko o kahi pahu pahu)
- Nū nā maka: ke aniani, ka aniani paha a me ka waihoʻoluʻu (5 ml kēlā me kēia i loko o nā pahu ihe mau pahu, 1 pahu i loko o ka pūlima pepa.
Aia ka hoʻonohonoho ʻana o ka papa pākuhi 1:
- Mea waiwai koʻikoʻi: ciprofloxacin - 250 a i ʻole 500 mg (i ke ʻano o ka citrrofloxacin hydrochloride monohydrate - 291.106 a 582.211 mg, ia manawa),
- ʻO nā mea kōkua (250/500 mg, kēlā): starch corn - 50.323 / 27.789 mg, cellulose microcrystalline - 7.486 / 5 mg, talc - 5/6 mg, sodium croscarmellose - 10/20 mg, colloidal silicon dioxide - 5/5 mg, ka lāʻau o ka paʻahau mago - 3.514 / 4.5 mg,
- Palapala wili (250/500 mg, ia): polysorbate 80 - 0,08 / 0.072 mg, hypromellose (6 cps) - 4.8 / 5 mg, titanium dioxide - 2 / 1.784 mg, sorbic acid - 0.08 / 0.072 mg Macrogol 6000 - 1.36 / 1.216 mg, talc - 1.6 / 1.784 mg, dimethicone - 0.08 / 0.072 mg.
ʻO ka hoʻonohonohoʻana o 100 ml o ka hoʻonā no ka hoʻopili e komo:
- Mea waiwai waiwai: ciprofloxacin - 200 mg,
- ʻO nā mea kōkua: sodium klorida - 900 mg, disodium edetate - 10 mg, lactic acid - 75 mg, citric acid monxidate - 12 mg, sodium hydroxide - 8 mg, hydrochloric acid - 0.0231 ml, wai no ka hōʻemi - a hiki i 100 ml.
ʻO ka hoʻonohonohoʻana o 1 ml mau maka e loaʻa ai:
- Mea waiwai waiwai: ciprofloxacin - 3 mg (ma ke ʻano o ka hydrochloride ciprofloxacin - 3.49 mg),
- ʻO nā mea kōkua: disodium edetate - 0,5 mg, acid hydrochloric - 0,000034 mg, sodium klorida - 9 mg, benzalkonium chloride 50% kūlohelohe - 0.0002 ml, wai no ka hōʻemi - a hiki i ka 1 ml.
Nā hōʻailona no ka hoʻohana ʻana
ʻO Ciprolet i ke ʻano o nā papa a me kahi hoʻonā infusion i kuhikuhi no ka mālama ʻana o nā maʻi ʻeha a me nā maʻi nāʻi ʻia e nā microorganisms i pili i ka hana a ciprofloxacin, me ka:
- Hoʻokomo i nā genital, respiratory tract, urinary tract a me nā keiki, ENT organ, bile ducts and gall bladder, skin, tissues soft and mucous membranes, musculoskeletal system, gastrointestinal tract (me nā niho, waha, waha. ʻāʻā)
- Peritonitis
- Sepsis.
Hoʻohana ʻia ka lāʻau lapaʻau i ka mālama ʻana a me ka pale ʻana i nā maʻi i nā maʻi me ka hoʻēmi ʻia o ka pale (i ka wā hoʻohana o nā immunosuppressants).
Hoʻomaʻamaʻa ʻia nā maka no Ciprolet no nā maʻi ʻeha a me nā ʻehaʻeha o ka maka a me kāna mau mea i hoʻokumu ʻia e nā maʻi maʻi e pili ana i ka hana o ka lāʻau lapaʻau, e komo pū ana:
- Blepharitis, blepharoconjunctivitis,
- Conjunctivitis (subacute and acute),
- Nā ulia maʻi kanaluma,
- ʻO ka dacryocystitis mānoopili a me meibomite,
- Keratoconjunctivitis a me nā keratitis bacteria.
Hōʻike pū ʻia nā pūpū no ka prophylaxis preoperative a me ka mālama ʻana i nā hoʻopiʻi maʻi postoperative i ka ophthalmosurgery a no ka hoʻopiʻi ʻana i nā maka maʻi ma hope o ke komo ʻana o nā kino ʻē aʻe a i ʻole hōʻeha (mālama a me ka pale ʻana).
Nā Hoʻohui
- Keratitis Viral (no ka hāʻule o ka maka),
- ʻO ka colitis Pseudomembranous (no nā papa a me ke kūpaʻa no ka infusion),
- ʻO ka nele o Glucose-6-phosphate dehydrogenase (no ka hoʻonā wai infusion),
- ʻAe a hiki i 1 makahiki (no nā maka o ka maka) a i ʻole 18 mau makahiki (no nā papa a me ke kūpaʻa no ka infusion).
Nā koho hoʻohālikelike no nā puka āpau e hoʻokuʻu ai:
- ʻŌpū a me ka lactation
- ʻO ka hypersensitivity i nā mea o ka lāʻau lapaʻau a i ʻole nā lāʻau'ē aʻe mai ka hui o ka fluoroquinolones.
Me ka mālama aka, pono e kau ʻo Tsiprolet i nā ʻano āpau āpau i ka poʻe maʻi me ka atherosclerosis koʻikoʻi o nā moku cerebral, nā māka cerebrovascular a me nā maʻi hoʻomanawanui.
Pono e hana pono i ka lāʻau lapaʻau me ka mālama nui i nā mea maʻi, a me ka epilepsy, maʻi noʻonoʻo, maʻi hepatic a / a i ʻole ka hopena ʻole.
ʻLoe a me ke kākele
Hoʻoholo ʻia ka ʻai iki o Ciprolet ma ke ʻano o ka hoʻokuʻu ʻana o ka lāʻau, ka hōʻeha o ka maʻi, ke ʻano o ka maʻi ʻeha, ke ʻano o ke kino, ke kaumaha o ke kino, ka makahiki a me ke ʻano o nā kau.
ʻO ka Ciprolet i ke ʻano o nā papa i lawe ʻia ma ka waha, ma kahi ʻōpū ʻole, me nā wai nui.
E like me ke kānāwai, ua kuhikuhi ʻia kēia mauʻano hoʻohālikelike:
- ʻO nā maʻi kumu ʻole o ka pāpīpī a me nā puʻuwai, nā maʻi o ka ʻōpū hanu haʻahaʻa o ke ʻano hōʻeha: i nā manawa 2 i ka lā, 250 mg pākahi i kēlā me kēia, i nā maʻi koʻikoʻi o ka maʻi, hoʻokahi pae e hoʻonui i ka 2 mau manawa,
- Gonorrhea: 250-500 mg hoʻokahi,
- Nā maʻi gynecological, enteritis a me colitis me ke koʻikoʻi koʻikoʻi a me ke kiʻekiʻe kiʻekiʻe, ka prostatitis, osteomyelitis: mau manawa 2 i ka lā, 500 mg kēlā me kēia (ma ka mālama ʻana i nā maʻi maʻamau, hiki ke hoʻēmi ʻia ka pākahi i nā manawa 2).
Hoʻoholo ʻia ka lōʻihi o ka hiki ʻana i ka maʻi ma muli o ka uha o ka maʻi, akā, e pono e lawe ʻia ʻo Ciprolet no ka liʻiliʻi loa 2 mau lā ma hope o ka nalowale ʻana o nā hōʻailona o ka maʻi. I ka awelika, ʻo ka lōʻihi o ka papa he 7-10 lā.
Ma kahi o ka hana nui o ka haneli pōpilikia, 1 /2 dosis o ka lāʻau.
I ka hopena ʻole o ka renal ka hopena, ua hoʻoholo ʻia ka hoʻoponopono ʻia o ka hoʻoponopono ʻia ʻana e nā hana loea.
- ʻOi aku ma mua o 50 ml i hoʻokahi minuke: ke ʻano maʻamau
- 30-50 ml mau minuke: 1 ka manawa i 12 mau hola, 250-500 mg kēlā me kēia.
- 5-29 ml i hoʻokahi minuke: hoʻokahi manawa o 18 mau hola, 250-500 mg.
Hoʻohana ʻia ka poʻe maʻi e pili ana i ka dialysis peritoneal i hoʻokahi manawa i kēlā me kēia 24 hola me 250-500 mg (ma hope o ka dialysis).
ʻO Ciprolet i ke ʻano o kahi hopena no ka hoʻopuʻi ʻia e hoʻokaʻawale i ke kahuhina no 30 mau minuke (200 mg i kēlā me kēia) a me 60 mau minuke (400 mg i kēlā me kēia).
Ua kūpono ka ʻōlelo infusion me ka hoʻonā a Ringer, 0.9% vahaolana sodium klorida, 10% kūmole fructose, 5% a me ka hopena o ka dextrose 10%, a me kahi hopena no ka hopena 5% dextrose me 0.45% a i ʻole 0.225% vahaolana sodium klorida.
ʻO ka awelika helu hoʻokahi he 200 mg (no nā maʻi koʻikoʻi - 400 mg), ka pinepine o ka hoʻokele - 2 mau manawa i ka lā. Hoʻoholo ʻia ka lōʻihi o ka mālama ʻia e ka hōʻeha o ka maʻi a me nā kumu haʻahaʻa 7-14 lā. Inā kūpono, hiki ke hoʻohana ʻia ka lāʻau lapaʻau no kahi manawa lōʻihi.
I ka mālamaʻana i ka maʻi gonorrhea, hōʻike kahi hoʻokahi o ka hoʻokele intravenous o 100 mg o ka hopena.
No ka pale ʻana i nā maʻi postoperative, ke mālama ʻia nei ʻo Ciprolet ma ka 200-400 mg 30-60 mau minuke ma mua o ka hoʻomaʻemaʻe ʻana.
ʻO Kāololeta i ke ʻano o ka nānā ʻana i ka maka me ka ʻili.
Ma ka hopena e pili ana i ka maʻi hōʻeha a me nā maʻi maʻamau, i kēlā me kēia mau hola 4, hoʻokomo ʻia ka 1-2 i loko o ka ʻeke conjunctival o ka maka i hoʻopiʻi ʻia, ma nā hihia koʻikoʻi, 2 hāʻule i kēlā me kēia hola. Ma hope o ka holomua, ke emi nei ke kiko o nā instillations a me ke kaʻe.
I ka mālama ʻana i nā maʻi ulia bakaleola i ʻōlelo ʻia:
- Ka lā 1: kēlā me kēia mau minuke 15, 1 hāʻule no 6 mau hola, ma hope o kēlā me kēia 30 mau minuke i ka wā e ala ana, 1 hāʻule.
- I ka lā 2 - i kēlā me kēia hola i ala, ala 1 malama
- 3-lā 14 lā - kēlā me kēia hola 4 i ka wā e ala ai, 1 ka hāʻule.
Inā ma hope o 14 mau lā o ka lāʻau epithelization i hana ʻia, ʻaʻole hiki ke hoʻomau ʻia ka lāʻau lapaʻau.
Nā hopena hopena
I ka wā o ka hoʻohana ʻana iā Ciprolet i loko a i ka intravenously, hiki i nā hopena kūpono ke hopena:
- Pūnaehana Cardiovascular: nā arrhythmias cardiac, tachycardia, hoʻohaʻahaʻa i ke koko, ke alo o ka maka.
- Pūnaehana urinary: interstitial nephritis, hematuria, crystalluria (ma mua me ka diuresis haʻahaʻa a me ka ural alkaline), glomerulonephritis, polyuria, dysuria, albuminuria, mālama i ka urinary, hoʻohemo urethral, hoʻemi i ka hana excretory kidney.
- ʻŌnaehana musculoskeletal: ruptures tendon, arthralgia, tendovaginitis, arthritis, myalgia,
- Hematopoietic system: thrombocytosis, granulocytopenia, leukopenia, thrombocytopenia, anemia, leukocytosis, hemolytic anemia,
- Pūnaehana digestive: anorexia, ʻeha o ka ʻōpū, nausea, luaʻi, ʻeha ʻana o ka maʻi, flatulence, jaundice cholestatic (ʻoi aku hoʻi i nā mea maʻi me nā maʻi o ka palau mua), hepatonecrosis, hepatitis, hoʻonui i ka hana o nā transaminases hepatic a me ka phosphatase alkaline.
- Pūnaehana maʻi: puʻuwai, dizziness, tremor, luhi, insomnia, nightmares, peripheral paralgesia (anomaly i ka ʻike ʻana i ka ʻeha), hoʻonui nui intracranial pressure, luhi, hopohopo, hoʻomāinoino, hoʻomāinoʻewa, hallucinations, a me nā mea'ē aʻe o ke ʻano psychotic (i kekahi manawa hiki iā lākou ke holomua i nā kūlana i hiki i ka mea maʻi ke hōʻeha iā ia iho), nāwaliwali, ka migraine, ka trombosis cerebral arebral,
- Nā kino ʻeha: lohe hoʻolohe, tinnitus, ʻaila ʻole a me ka hoʻāʻo, ʻike ʻole ʻia o ka ʻike (diplopia, loli i ka ʻike ʻulaʻula).
- Nā hōʻailona Laboratory: hypercreatininemia, hypoprothrombinemia, hyperglycemia, hyperbilirubinemia,
- Nā ʻano maʻi: ke ʻano o nā ʻōpala o nā nodules liʻiliʻi a me nā blisters i hui pū ʻia e ka pehu, ka ʻeha ʻili, ke ala ʻana i ka maʻi, ka urticaria, ka hemorrhages (petechiae), vasculitis, laryngeal a edial facial, eosinophilia, pōkole o ka hanu, hoʻonui ʻia photosensitivity, erythema nodosum, exudative toxic ʻO ka necrolysis epidermal (kahi o ka Lyell's syndrome), ʻo Stevens-Johnson syndrome (erythema exudative erythema).
- ʻO nā mea'ē aʻe: nāwaliwali laulā, superinfection (kandidiasis, pseudomembranous colitis).
Me ka hoʻokele intravenous, hiki i nā hopena kūloko ke hōʻike, i hōʻike ʻia e ka ʻeha a me ke ahi ʻana ma ka wahi i ʻōlelo ʻia, ka hoʻomohala ʻana o ka phlebitis.
Ke hoʻohana nei ʻo Ciprolet i ke ʻano o ka nānā ʻana o ka maka, hiki i kēia mau maʻi ke ʻano:
- Organ of vision: burn, itching, hyperemia and mild tend of the conjunctiva, rare photophobia, swelling of eyelids, lacrimation, foreign body sensation in the eyes, emi a visual acuity, ka helehelena o ke aniani keʻokeʻo e hoʻopau i nā maʻi me ka ulula corneal, keratopathy, keratitis, corneal infiltration,
- Nā mea hou: ke kuʻi, ke ʻano kūlohelohe, ʻaʻole luhi - ka hoʻomohala ʻana o ka superinfection, kahi ʻatikala maikaʻi ʻole i ka waha ma hope o ka instillation.
Nā ʻōlelo kikoʻī
ʻO ka poʻe maʻi me ka epilepsy, he mōʻaukala o ka makeʻe, nā maʻi vascular a me ka hōʻino o ka lolo kino ma muli o ka weliweli o nā hopena maikaʻi loa mai ka pūnaehana nū o mua e pono ke kuhikuhi iā Ciprolet i loko no nā kumu olakino wale nō.
Inā ma ka manawa a ma hope o ka hoʻohana ʻana o ka lāʻau lapaʻau, e hele a hōʻeha paha i nā maʻi aʻeha paha i loko o ia mea a i ʻole intravenously, e pono ke kāpae i ka noho ʻana o pseudomembranous colitis, ka mea e koi koke i ka wehe ʻana iā Ciprolet a me ka koho ʻana i ka hopena kūpono. Pono e hoʻoneʻe ʻia ka mālama ʻana me ka hoʻomohala ʻana i ka ʻeha i nā tendons a i ʻole me nā ʻano o nā hōʻailona mua o ka tenosynovitis.
I ka wā o ka hoʻohana ʻana i ka lāʻau lapaʻau i ke ʻano me nā papa a me kahi hopena no ka infusion, e hāʻawi ʻia kahi nui o ka wai o ka wā e nānā ana i ka diuresis maʻamau.
Hiki ke hoʻohana ʻili i ka maka kuʻuna ʻo Ciprolet ma luna o ka maka, hiki ʻole ke kaha i ke kau ʻana i ka lāʻau lapaʻau i loko o ke keʻena o mua o ka maka a i ka subconjunctival. I ka wā e hoʻohana ai i ka lāʻau lapaʻau a me nā hopena ophthalmic ʻē aʻe, ʻo ka manawa ma waena o kā lākou mau lawelawe e liʻiliʻi ma kahi o 5 mau minuke. ʻAʻole mālama ʻia nā lole lono no ka mālama ʻana.
Ke hoʻohana nei iā Tsiprolet, pono mālama ʻia i ka wā e hoʻokele a hana i nā ʻano ʻē aʻe ʻē aʻe o ka hana e koi nui ana a me ka wikiwiki psychomotor ʻano (ʻo ka hui pū me ka waiʻona).
Hoʻohui nūhou
Ma ka hihia o ka hoʻohana pinepine ʻana o Ciprolet me kekahi mau lāʻau lapaʻau, hiki i nā hopena kūpono ʻole:
- Didanosine: i hōʻemi ʻia i ka lawe ʻana o ciprofloxacin,
- Theophylline: kahi hoʻonui i kona neʻe i ka plasma koko a me ka hopena o ka hoʻomohala ʻana i ka hopena olakino,
- ʻO nā anakopa, a me nā mākaukau e pili ana i ka zinc, alumini, magnesium a me nā mea hao paha: ua hoʻemi ʻia ka lawe ʻana ʻana o nā ciprofloxacin (ʻo ke kikowaena ma waena o ka hoʻohana ʻana i kēia mau lāʻau me ka liʻiliʻi loa he 4 mau hola).
- Anticoagulants: wā aloha koko,
- Cyclosporin: hoʻonui nephrotoxicity,
- ʻO nā lāʻau anti-inflammatory nonsteroidal (koe wale nō i ka acetylsalicylic acid): ʻoi aku ka nui o nā kuʻi,
- Metoclopramide: ka wikiwiki o ka lawe ʻana o ka ciprofloxacin,
- Hoʻomākaukau Uricosuric: kāpae i ka haʻalele a hoʻonui i ka neʻe plasma o ka ciprofloxacin,
- Kāohi i kahi anticoagulants: hoʻonui i kā lākou hana.
Me ka hana like o Ciprolet me nā lāʻau antimicrobial ʻē aʻe, hiki i kahi synergy o ka hana. Wahi i ka maʻi, hiki ke hoʻohana ʻia iā Ciprolet me ka hoʻohui pū me nā lāʻau lapaʻau e hiki mai ana:
- Azlocillin, ceftazidime: nā maʻi i hoʻokumu ʻia e Pseudomonas spp.,
- Meslocillin, azlocillin a me nā mea hou o ka beta-lactam antibiotics: nā maʻi streptococcal,
- Isoxazolylpenicillins a me vancomycin: staph maʻi,
- Metronidazole, clindamycin: maʻiʻino anaerobic.
ʻO ka hoʻonāʻauʻana o ka infusion Ciprotet ka lāʻau lapaʻau i kūpono ʻole i nā lāʻau āpau a me nā hopena infusion e kūlohelohe ai ke kino a me ke kūlohelohe ma lalo o nā kūlana acidic (ʻo ka pH o nā hopena infusion ciprofloxacin he 3.5-4.6). ʻAʻole hiki ke hoʻohui i ka hoʻonā o ka hoʻokō intravenous me nā hopena e ʻike ai ka pH i ka 7.