ʻO Augmentin i ke ʻano o ka hoʻokuʻu ʻana: nā ʻōlelo i hoʻohana no nā keiki

ʻO ka pauka no ka hoʻomākaukau ʻana no ke keʻakeʻa ʻana no ka hoʻokele waha ʻana i ke keokeo a i ʻole hoʻi ke keʻokeʻo, me kahi ʻano ʻalaʻā, a i ka wā e hoʻokaʻawale ʻia, ʻike ʻia ke ʻano lae ke keʻokeʻo a ʻāhiʻokeʻo paha ke kūpaʻa ʻana, ke kū nei, kahi neʻe i ke keokeo a i ʻole hoʻi ke keʻokeʻo e hana lohi.

5 ml o ka pohō hoʻohemo ʻana.
amoxicillin (i ke ʻano o ka amoxicillin trihydrate)125 mg
clavulanic acid (ma ke ʻano o ka pā clavulanate potassium) *31.25 mg

Nā mea kūʻai: xanthan gum - 12,5 mg, aspartame - 12,5 mg, acid acidcinic - 0.84 mg, colloidal silicon dioxide - 25 mg, hypromellose - 150 mg, ʻono wai ʻulaʻa 1 - 15 mg, ʻono wai ʻeke 2 - 11.25 mg, ʻōpula ʻōpala - 22,5 mg, ʻākāwili "nā pōpō kukui" - 23.75 mg, silika ʻona - 125 mg.

11.5 g - nā hue aniani (1) hoʻopiha me kahi pōpoki ana - nā ʻeke pepa.

ʻO ka pauka no ka hoʻomākaukau ʻana no ke keʻakeʻa ʻana no ka hoʻokele waha ʻana i ke keokeo a i ʻole hoʻi ke keʻokeʻo, me kahi ʻano ʻalaʻā, a i ka wā e hoʻokaʻawale ʻia, ʻike ʻia ke ʻano lae ke keʻokeʻo a ʻāhiʻokeʻo paha ke kūpaʻa ʻana, ke kū nei, kahi neʻe i ke keokeo a i ʻole hoʻi ke keʻokeʻo e hana lohi.

5 ml o ka pohō hoʻohemo ʻana.
amoxicillin (i ke ʻano o ka amoxicillin trihydrate)200 mg
clavulanic acid (ma ke ʻano o ka pā clavulanate potassium) *28.5 mg

Nā mea kūʻai: xanthan gum - 12,5 mg, aspartame - 12,5 mg, acid acidandric - 0.84 mg, colloidal silicon dioxide - 25 mg, hypromellose - 79.65 mg, ʻono ʻeke o ka wai - 1 - 15 mg, ʻono wai ʻeke 2 - 11.25 mg, ʻōpala ʻōpala - 22,5 mg, Flavor "Molases" - 23.75 mg, silic dioxide - a hiki i 552 mg.

7.7 g - nā ipu aniani (1) hoʻopiha me kahi pōpoki ana - nā ʻeke pepa.

ʻO ka pauka no ka hoʻomākaukau ʻana no ke keʻakeʻa ʻana no ka hoʻokele waha ʻana i ke keokeo a i ʻole hoʻi ke keʻokeʻo, me kahi ʻano ʻalaʻā, a i ka wā e hoʻokaʻawale ʻia, ʻike ʻia ke ʻano lae ke keʻokeʻo a ʻāhiʻokeʻo paha ke kūpaʻa ʻana, ke kū nei, kahi neʻe i ke keokeo a i ʻole hoʻi ke keʻokeʻo e hana lohi.

5 ml o ka pohō hoʻohemo ʻana.
amoxicillin (i ke ʻano o ka amoxicillin trihydrate)400 mg
clavulanic acid (ma ke ʻano o ka pā clavulanate potassium) *57 mg

Nā mea kūʻai: xanthan gum - 12,5 mg, aspartame - 12,5 mg, acid acidandric - 0.84 mg, colloidal silicon dioxide - 25 mg, hypromellose - 79.65 mg, ʻono ʻeke o ka wai - 1 - 15 mg, ʻono wai ʻeke 2 - 11.25 mg, ʻōpala ʻōpala - 22,5 mg, ka ʻōhuhu "Ka ʻala ʻilohi" - 23.75 mg, silika ʻona a hiki i 900 mg.

12.6 g - nā hue wai (1) hoʻopiha me kahi pōpoki ana - nā ʻeke pepa.

* i ka hana o ka lāʻau, hoʻokomo ʻia ka pā clavulanate me ka nui o ka 5%.

Ka hana lāʻau lapaʻau

ʻO Amoxicillin kahi antibiotic ākea ākea ākea me ka hana e kūʻē i nā microorganisms gram-maikaʻi a me ka gram-negatif. I ka manawa like, hiki i ka amoxicillin ke hōʻemi ʻia e ka β-lactamases, a no laila ʻaʻole ka hoʻonuiʻana i nā mea hana o ka amoxicillin i nā microorganism e hana ai kēia enzyme.

ʻO Clavulanic acid, kahi β-lactamase inhibitor structurally pili i penicillins, hiki i ka hana ke hana i ka nui o nā β-lactamases i loaʻa i ka penicillin a me nā microorganisms kūpaʻa cephalosporin. Ua lawa ka hopena o ka waʻa Clavulanic e kū'ē i ka plasmid β-lactamases, ka mea pinepine e hoʻoholo ai i ka kūʻē o nā huakini, a i ʻole ka hopena i ka chromosomal β-lactamases o ka ʻano 1, ka mea i pale ʻole ʻia e ka clavulanic acid.

ʻO ka heleʻana o ka acid clavulanic i ka mākaukau o Augmentin ® mālama i ka amoxicillin mai ka luku ʻia e nā enzymes - β-lactamases, kahi e hiki ai ke hoʻonui i ke kiko o ka antibacterial o amoxicillin.

ʻO ka mea aʻe ka hana hoʻohui vitro o ka amoxicillin me ka waila clavulanic.

ʻO nā bakteria maʻamau i maʻalahi i ka hui pūʻana o ka amoxicillin me ka waikawa clavulanic

Aerobes Gram-positive: Bacillus anthracis, Enterococcus faecalis, Listeria monocytogenes, Nocardia asteroides, Streptococcus pyogenes 1,2, Streptococcus agalactiae 1,2, Streptococcus spp. (manuahi ʻē aʻe Hepolytic streptococci) 1,2, Staphylococcus aureus (pili i ka methicillin) 1, Staphylococcus saprophyticus (pili i ka methicillin), Staphylococcus spp. (coagulase-hewa, paʻakikī i ka methicillin).

Aerobes Gram-néleple: Bordetella pertussis, Haemophilus influenzae 1, Helicobacter pylori, Moraxella catarrhalis 1, Neisseria gonorrhoeae, Pasteurella multocida, Vibrio cholerae.

Anaerobes Gram-positive: Clostridium spp., Peptococcus niger, Peptostreptococcus magnus, Peptostreptococcus micros, Peptostreptococcus spp.

Anaerobes Gram-negative: Bacteroides fragilis, Bacteroides spp., Capnocytophaga spp., Eikenella corrodens, Fusobacterium nucleatum, Fusobacterium spp., Porphyromonas spp., Prevotella spp.

ʻO kekahi: Borrelia burgdorferi, Leptospira icterohaemorrhagiae, Treponema pallidum.

Hiki i nā maʻi ke loaʻa i ka kū kūʻē i ka hui pū ʻana o ka amoxicillin me ka clavulanic acid

Aerobes Gram-néleast: Escherichia coli 1, Klebsiella oxytoca, Klebsiella pneumoniae 1, Klebsiella spp., Proteus mirabilis, Proteus vulgaris, Proteus spp., Salmonella spp., Shigella spp.

Aerobes Gram-positive: Corynebacterium spp., Enterococcus faecium, Streptococcus pneumoniae 1,2, Streptococcus hui Viridans 2.

ʻO nā hua maʻi kūlohelohe kūlohelohe i ka hui pūʻana o ka amoxicillin me ka clavulanic acid

Aerobes Gram-nélealea: Acinetobacter spp., Citrobacter freundii, Enterobacter spp., Hafnia alvei, Legionella pneumophila, Morganella morganii, Providencia spp., Pseudomonas spp., Serratia spp., Stenotrophomonas maltophilia, Yersinia enter.

Other: Chlamydia pneumoniae, Chlamydia psittaci, Chlamydia spp., Coxiella burnetti, Mycoplasma spp.

1 No kēia mau ʻano microorganisms, ua hōʻike ʻia ke ola kino o ka hui o ka huixicillin me ka clavulanic acid.

2 O nā kūlima o kēia mau ʻano o nā huakini ʻaʻole ia e hana i ka β-lactamases. ʻO ka uluʻana me ka monocroʻo laxicillin e hōʻike i ka hoʻowalewale like i ka hui pū ʻana o ka amoxicillin me ka clavulanic acid.

Lapaʻau lāʻau

ʻO nā mea ʻelua e hoʻohana ai i ka lāʻau Augmentin ®, amoxicillin a me ka acid clavulanic, ke wikiwiki a holo a piha loa mai ka gastrointestinal tract ma hope o ka lawelawe waha. ʻO ka wehe ʻana o nā mea ikaika e kūpono loa ka lawe ʻana i ka lāʻau lapaʻau ma ka hoʻomaka ʻana o kahi pāʻina.

Augmentin ® 125 mg / 31.25 mg no 5 ml oral suspension powder

Ke hōʻike nei ka lāʻau lapaʻau pharmacokinetic o amoxicillin a me ka waikawa clavulanic i loaʻa i nā haʻawina like ʻole ma lalo nei, i ka wā i ʻike ʻia ai nā mea hana olakino maikaʻi ʻo 2-12 mau makahiki i ka ʻōpū hakahaka 40 mg / 10 mg / kg momona kino / lā o ka lāʻau Augmentin ®, ka pauku no ka hoʻokuʻu ʻia ʻana no ke alakaʻi ʻana i nā 3osa ma ka waha, 125 mg / 31.25 mg ma 5 ml (156.25 mg).

Nā lamaʻehā pharmacokinetic kumu

HoʻomoeDosis
(mg / kg)
C max
(mg / l)
T max (h)Auc
(mg × h / l) ka
T 1/2 (h)
Amoxicillin
Augmentin ® 125 mg / 31.25 mg no 5 ml407.3±1.72.1 (1.2-3)18.6±2.61±0.33
Clavulanic waikawa
Augmentin ® 125 mg / 31.25 mg no 5 ml102.7±1.61.6 (1-2)5.5±3.11.6 (1-2)

Augmentin ® 200 mg / 28.5 mg ma 5 ml oral suspension powder

Ke hōʻike nei nā lāʻau lapaʻau ʻo ka pharmacokinetic o amoxicillin a me ka waikawa clavulanic i loaʻa i nā haʻawina like ʻole ma lalo nei, i ka wā i ʻike ʻia ai nā mea hana olakino ʻo 2-12 mau makahiki i ka ʻōpū ʻole e lawe ana iā Augmentin ®, ka pauka no ka hoʻokuʻu puki ʻana, 200 mg / 28.5 mg ma 5 ml (228.5 mg) i ka make o 45 mg / 6.4 mg / kg / lā, ua māhele ʻia i 2 mau pona.

Nā lamaʻehā pharmacokinetic kumu

ʻO ke ʻano waiwaiC max (mg / l)T max (h)AUC (mg × h / l) kaT 1/2 (h)
Amoxicillin11.99±3.281 (1-2)35.2±51.22±0.28
Clavulanic waikawa5.49±2.711 (1-2)13.26±5.880.99±0.14

Augmentin ® 400 mg / 57 mg keleawe waha ma 5 ml

Ke hōʻike nei ka lāʻau lapaʻau pharmacokinetic o amoxicillin a me ka acid clavulanic i loaʻa i nā haʻawina ʻokoʻa ma lalo nei, i ka manawa i lawe ai nā mea ola olakino i hoʻokahi dosis o Augmentin ®, ka pauka no ka pohō o ka waha, 400 mg / 57 mg ma 5 ml (457 mg).

Nā lamaʻehā pharmacokinetic kumu

ʻO ke ʻano waiwaiC max (mg / l)T max (h)AUC (mg × h / l) ka
Amoxicillin6.94±1.241.13 (0.75-1.75)17.29±2.28
Clavulanic waikawa1.1±0.421 (0.5-1.25)2.34±0.94

E like me ka lōnaehana iv o ka hui pū ʻana o ka amoxicillin me ka clavulanic acid, ka paʻa ʻana o ka therapeutic o ka amoxicillin a me nā kūmole clavulanic i loaʻa i nā ʻano o nā umau a me nā kiko, ka waiʻi interstitial (nā kino o ka ʻōpū o ka ʻōpū, adipose, iwi a me nā kiko o ka ʻōpū, ka synovial a me ka peritoneal flu, ka ʻili, ka ʻili, a me ka hoʻoiho purulent) )

ʻO Amoxicillin a me clavulanic acid ka mea nāwaliwali ikaika i ka paʻa ʻana i nā protein plasma. Ua hōʻike nā noiʻi e pili ana i 25% o ka nui o ka nui clavulanic acid a me 18% o ka amoxicillin e hoʻopaʻa ai i nā protein plasma koko.

I nā noiʻi holoholona, ​​ʻaʻole i ʻike ʻia ka hoʻohui ʻia o nā mea o ka lāʻau Augmentin ®.

ʻO Amoxicillin, e like me ka hapa nui o nā penicillins, i hele i loko o ka waiū umauma. Loaʻa ka loaʻa o nā punawai clavulanic i nā umauma umauma. Me ka ʻokoʻa ʻole o ka hiki ʻana o ka naʻau, ʻike ʻia ka hoʻomohala ʻana a me ka candidiasis o nā membous mucous waha, ʻaʻohe hopena maikaʻi ʻole o ka amoxicillin a me ka clavulanic acid ma ke olakino o nā keiki hānai hānai. Ua hōʻike ʻia nā noi ʻana o ka hana hānau i loko o nā holoholona i ka amoxicillin a me ke kūleʻa clavulanic e hele i ka pale o ka placental, me nā hōʻailona ʻole o nā hopena pōpilikia i ka pūpū.

ʻO 10-25% o ka pākuʻi mua o ka amoxicillin i hoʻopili ʻia e nā pōpoki ma ke ʻano o kahi metabolite kaheʻoleʻai (penicilloic acid). ʻO ka waikawa Clavulanic i hoʻohālikelike nui i ka 2,5-dihydro-4- (2-hydroxyethyl) -5-oxo-1H-pyrrole-3-carboxylic acid a me 1-amino-4-hydroxy-butan-2-hoʻokahi a hoʻopā ʻia e nā keiki. ma o ka digestive tract, a me ka hau i pau i ke ano o ke hone.

E like me nā penicillins ʻē aʻe, ua hoʻohana nui ʻia ka amoxicillin e nā ʻōpū, aʻo ka clavulanic acid i ʻoki ʻia e nā pūniki a me nā hana pū. Ma kahi o 60-70% o amoxicillin a ma kahi o 40-65% o ka clavulanic acid e hoʻopiʻi ʻia e nā keiki i hoʻololi ʻole ʻia i nā hola 6 mua ma hope o ka lawe ʻana i ka papa 1 o 250 mg / 125 mg a i 1 papa o 500 mg / 125 mg.

Nā ʻĀina Augmentin ®

ʻO nā maʻi maʻi maʻi ma muli o nā micro-sensitive microorganisms:

  • nā maʻi o ka ʻōpū hanu o luna a me nā kino ENT (e ..g., tonsillitis ka hoʻomaka ʻana, sinusitis, otitis media), maʻamau ke kumu o ka Streptococcus pneumoniae, Haemophilus influenzae *, Moraxella catarrhalis *, Streptococcus pyogenes,
  • ʻōpū o ka hanu haʻahaʻa haʻahaʻa: exacerbations of bronchitis chronic, lobar pneumonia and bronchopneumonia, maʻamau i kumu no e Streptococcus pneumoniae, Haemophilus influenzae * a Moraxella catarrhalis *,
  • ka maʻi ʻeha o ka urary: cystitis, urethritis, pyelonephritis, maʻi ʻana o nā ʻōpiopio wahine, maʻamau i nā ʻano o ka ʻohana Enterobacteriaceae (ka nui Escherichia coli *), Staphylococcus saprophyticus a me nā ʻano o ka genus Enterococcus,
  • ua kumu ʻia e Neisseria gonorrhoeae *,
  • ka maʻi ʻana o ka ʻili a me nā lau palupalu, e laʻa ʻia e Staphylococcus aureus *, Streptococcus pyogenes a me nā ʻano o ka ʻano Bactero> * ʻO kekahi mau inoa o kēia ʻano ʻano microorganisms i hana i ka β-lactamase, ka mea e hoʻolako iā lākou i ka amoxicillin.

ʻO nā maʻi i hoʻomake ʻia e nā microorganisms i kūpono i ka amoxicillin e hiki ke mālama ʻia me Augmentin ®, no ka mea ʻo ʻAxinopillin kekahi o kāna mea hana.

Hoike pū ʻia ʻo Augmentin ® no ka mālama ʻana i nā ʻili like i hoʻoili ʻia e nā microorganisms i pili i ka amoxicillin, a me nā microorganism e hana ana i ka β-lactamase, pili i ka hui pū ʻana o ka amoxicillin me ka clavulanic acid.

ʻO ka lili ʻana o nā maʻi i ka hui pū ʻana o ka amoxicillin me ka clavulanic acid e like me ka palena a me ka wā. Ma kahi e hiki ai, e noʻonoʻo pono i ka ʻikepili hālima. Inā pono, pono e hōʻiliʻili ʻia nā mea ʻike microbiological a hoʻopaʻa ʻia no ka naʻau bacteriological.

Nā helu ICD-10
Aia ka helu ICD-10Hōʻike ʻano
A54ʻO ka maʻi Gonococcal
H66Pūnaewele ma Purulent a i ʻole i kikoʻī ʻia
J01Sinusitis huehue
J02ʻO ka pharyngitis akue
J03Tonsillitis huehue
J04ʻO ka laryngitis hoʻonani a me ka tracheitis
J15ʻO nā maʻi maʻi pneumonia, ʻaʻole kahi ʻokoʻa i kahi ʻē
J20Nā keleahi bronchitis
J31Rhinitis wāhole, nasopharyngitis a me pharyngitis
J32Sinusitis wāhole
J35.0He mau tonsilitis wāwahi
J37ʻO ka laryngitis maʻi a me ka laryngotracheitis
J42Palapala bronchitis, ʻaʻole i hoʻomaopopo ʻia
L01Impetigo
L02ʻO ka pohō ʻili, hoʻolapalapa a me ka carbuncle
L03Phlegmon
L08.0Pyoderma
M00ʻĀpilikia Pyogenic
M86Osteomyelitis
N10Nephritis Acul tubulointerstitial (pyelonephritis paleka)
N11Nephritisitis tubulointerstitial palula (pyelonephritis palola)
N30Cystitis
N34ʻO ka maʻi urethritis a me ka urethral syndrome
N41Hoʻopilikia i nā maʻi o ka prostate
N70Salpingitis a me ooporitis
N71ʻO ka maʻi pāpaʻi o ka ʻōpū, koe me ka cervix (me ka endometritis, myometritis, metritis, pyometra, kaʻe ʻana o ka ʻōpū)
N72ʻEha nā maʻi lōkahi (komo i ka cervicitis, endocervicitis, exocervicitis)
T79.3ʻO ka maʻi hōʻeha o ka ʻeha post-traumatic, ʻaʻole ma kahi ʻē aʻe

Ka hoʻoponopono ʻia ʻana

Lawe ʻia ka lāʻau lapaʻau.

Hoʻonohonoho ka dosimen dosage i kū hoʻokahi i ka makahiki, ke kino, ke kaupaona ʻana o ka hana a ka mea maʻi, a me ka nui o ka maʻi.

No ka haʻaluhi ʻana a maikaʻi loa a me ka hoʻēmi ʻana i nā hopena hopena mai ka hoʻopili ʻana, pono ʻia ʻo Augmentin ® e lawe ʻia i ka hoʻomaka ʻana o kahi pāʻina.

ʻO ka papa haʻahaʻa o nā mea maʻi maʻiʻo 5 mau lā.

ʻAʻole pono e hoʻomau ka hoʻomehana no nā lā 14 me ka ʻole o ka loiloi o ke kūlana haukapila.

Inā pono, hiki iā ia ke hana i ka hoʻokalakupua i ke ʻano (ma ka hoʻomaka ʻana o ke ʻano, ʻo ka hoʻomanawanui makua o ka lāʻau me ka hoʻololi hou ʻana i ka lawelawe waha).

ʻO nā pākeke a me nā keiki ma mua o 12 mau makahiki a koʻikoʻi paha he 40 kg a keu paha

Hoʻomaopopo ʻia e hoʻohana i nā ʻano lāʻau ʻē aʻe o Augmentin ® a i ʻole kahi hoʻokuʻu ʻia me ka ratio o ka amoxicillin i ka clavulanic acid 7: 1 (400 mg / 57 mg ma 5 ml).

ʻO nā keiki he 3 mau mahina a 12 mau makahiki me ke kaumaha o ke kino ma lalo o 40 kg

Hoʻolaha ʻia ka helu helu ʻana ma muli o ka makahiki a me ke kaumaha o ke kino, i hōʻike ʻia ma ke ʻano he nui mg / kg kino kino / lā (helu helu ma ke ʻano ʻoxxillillin) a i loko o ka mol o ka pakanā ʻana.

ʻO ka hoʻonui pinepine ʻana o ka hāpai ʻana i ka 125 mg / 31.25 mg ma 5 ml he 3 mau manawa / lā i kēlā me 8 mau hola.

ʻO ka hoʻonuiʻana o ka hoʻokuʻuʻana i ka 200 mg / 28.5 mg ma 5 ml a i ka 400 mg / 57 mg ma 5 ml - 2 mau manawa / lā i kēlā me kēia hola 12.

Hōʻike ʻia ka papa helu dosage i ʻōlelo ʻia ʻia a me nā pinepine o ka lawelawe i ka papa ma lalo.

Augmentin ® dosage regimen table (helu helu ana no amoxicillin)

Hoʻohui pinepine ʻia - 3 manawa / lā
Hoʻopaʻa 4: 1 (125 mg / 31.25 mg ma ka 5 ml)
Hoʻohui i ka hoʻonui ʻia - 2 manawa / lā
Hoʻopaʻa 7: 1 (200 mg / 28.5 mg ma 5 ml a i ka 400 mg / 57 mg ma 5 ml)
Nā helu liʻiliʻi loa20 mg / kg / lā25 mg / kg / lā
ʻO nā helu kiʻekiʻe40 mg / kg / lā45 mg / kg / lā

Hoʻohana ʻia nā dosis liʻiliʻi o Augmentin ® e mālama i nā hōʻeha o ka ʻili a me nā pāloʻi palupalu, a me ka tonillitis mau hoʻi.

Hoʻohana ʻia nā dosis nui o Augmentin ® e mālama i nā maʻi e like me ka otitis media, sinusitis, lalo o ka hanu a me nā maʻi a me ka maʻi ʻokiʻoki, a me nā iwi a me nā maʻi hui pū ʻana.

ʻAʻohe lawa o nā ʻike kulekele e hōʻike i ka hoʻohana ʻana o Augmentin ® i kahi maʻa o ka ʻoi aku ma mua o 40 mg / kg / lā ma 3 mau ʻoka hoʻokaʻawale (4: 1 suspension) a me 45 mg / kg / lā ma 2 mau haʻawina i hoʻokaʻawale ʻia (7: 1 suspension) i lawa ʻole i ka ʻikepili lapaʻau e hōʻike i ka hoʻohana ʻana o nā ka make ma loko o nā keiki i lalo o nā makahiki o 2.

Na keiki mai ka hanau a 3 mahina

Ma muli o ka maikaʻi o ka hana excretory o nā pēpē, ʻo ka ʻāpono i hōʻike ʻia ʻo Augmentin ® (helu helu no kaxxillillin) ʻo 30 mg / kg / lā ma 2 mau māhele i māhele ʻia o 4: 1.

ʻO ka hoʻohana ʻana o kahi pānaʻi he 7: 1 (200 mg / 28.5 mg ma 5 ml a i ʻole 400 mg / 57 mg ma 5 ml) i pāpā ʻia i kēia heluna.

Pēlā keiki

ʻAʻohe mea hāʻawi e pili ana i ka regimen dosage.

ʻO nā maʻi maʻi

ʻAʻohe koi hoʻoponopono hoʻoponopono. I nā poʻe maʻi me nā hana renal impaired, pono ke hoʻoponopono ʻia ke ʻano e like me nā poʻe maʻi me ka hana ʻole o ka mālamalama.

ʻO ka maʻi me ka hana renal impaired

Kuhi ʻia ka hoʻoponopono ʻana i ka dosis me ka nui o ka ʻōlelo koi a ka amoxicillin a lawe ʻia i nā waiwai o QC.

QCKe kali 4: 1
(125 mg / 31.25 mg ma ka 5 ml)
> 30 ml / minʻAʻole pono kahi hoʻoponopono hoʻoponopono ʻia
10-30 ml / min15 mg / 3.75 mg / kg 2 mau manawa / lā, ʻo ka nui loa ka 500 mg / 125 mg 2 mau manawa / lā
nā mea maʻi me CC> 30 ml / min, me ka hoʻoponopono ʻia ʻana ʻaʻole pono.

I ka nui o nā hihia, inā hiki, e koho ʻia ka lawelawe makua.

Nā maʻi maʻi Hemodialysis

ʻO ka regimen dute ʻōlelo ʻia ʻo 15 mg / 3.75 mg / kg 1 manawa / lā.

Ma mua o kahi hālāwai hemodialysis, pono e lawelawe ʻia i kekahi nui o 15 mg / 3.75 mg / kg. E hoʻihoʻi hou i ka ʻike o nā mea ikaika o ka lāʻau Augmentin ® i loko o ke koko, e hoʻolako ʻia i kahi lua o 15 mg / 3.75 mg / kg ma hope o kahi hālāwai hemodialysis.

ʻO nā mea maʻi me ka hana pūlima hemahema

Hoʻohana ʻia ka mālama ʻana me ka akahele; ʻAʻole lawa nā ʻikepili e hoʻoponopono i ka regimen dosis i kēia māhele o nā maʻi.

Na rula no ka hoomakaukau ana o ka hoopanee ana

ʻAno hoʻomākaukau ʻia ka hoʻopanalo ma mua o ka hoʻohana mua ʻana.

Hoʻomoe ʻano hānau. A laila hoʻohui i ka wai i ka māka ma ka pahu a lūlū hou i ka hue hou. I ka huina, e pili ana i ka 92 ml o ka wai e hoʻomākaukau no ka hoʻokuʻu ʻana.

Hoʻomaʻamaʻa (200 mg / 28.5 mg ma 5 ml a i 400 mg / 57 mg ma 5 ml): hoʻohui i kahi o 40 ml o ka wai kuke i hoʻoluʻu ʻia i ka lumi lumi i loko o ka paukū pauka, a laila e pani i ka pahu me kahi uhi a lulu a hiki i ka pau ʻana o ka pauka, hāʻawi kū i ke kīʻaha no 5 mau minuke i mea e hōʻoia pono ai ka hoʻomaloʻo. A laila hoʻohui i ka wai i ka māka ma ka pahu a lūlū hou i ka hue hou. I ka huina, e pili ana i 64 ml wai e hoʻomākaukau ai i ka pēpē.

No nā keiki i lalo o 2 mau makahiki o ke ʻano, hiki i kahi hapa pākahi i hoʻolei ʻia i ka hoʻomākaukau o Augmentin ® ka mea i hoʻoheheʻe ʻia me ka wai ma kahi hoʻohālike o 1: 1.

Pono e lūlū maikaʻi ʻia ka pahu i mua o kēlā me kēia hoʻohana. No ka hoʻonui pono ʻana i ka lāʻau lapaʻau, pono e hoʻokaʻawale ʻia kahi kapa pale, pono e holoi maikaʻi ʻia me ka wai ma hope o kēlā me kēia hoʻohana. Ma hope o ka ninini ʻana, pono e mālama ʻia ka hoʻopiʻi ʻana no 7 mau lā i loko o ka friji, akā ʻaʻole maloʻo.

Loaʻa ka hopena

Palapala ʻia nā hanana keu i hōʻike ʻia e like me ka pōʻino o nā mea ola a me nā ʻōnaehana a me ka pinepine o ka hiki ʻana. Hoʻoholo ʻia ka alapine me ka pinepine e pili ana i ka manawa: pinepine pinepine (≥1 / 10), pinepine pinepine (≥1 / 100, nā maʻi maʻi a me nā maʻi parasitite: pinepine - kandidiasis o ka ʻili a me nā membrane mucous.

Mai ka ʻōnaehana hemopoietic: līlou - hiki i ka leukopenia hoʻihoʻi (me ka nuku neutropenia) a me ka thrombocytopenia hoihoi, ʻokoʻa loa - ka wā agranulocytosis hōkū a hiki ke hoʻoliuli hou ʻia, ka lōʻihi o ka manawa prothrombin a me ke wā kahe, ka anemia, eosinophilia, thrombocytosis.

Mai ka pānaʻi ʻana: ākea loa - angioedema, anaphylactic reaksi, kahi ʻeha like me ka maʻi serum, vasculitis allergic.

Mai ka pūnaehana pīhoihoi: pinepine - nā maʻi, hōʻeha, hōʻeha, hiki ke hoʻōla - hoʻololi i ka hyperactivity, hoʻopaʻapaʻa (hoʻopaʻi ʻia hiki i nā mea maʻi ke hana ʻole ʻia ka hopena, a me ka poʻe e loaʻa nā kiʻekiʻe o ka lāʻau lapaʻau), ka ʻahaʻeha, ka huhū, ka hopohopo, ke ʻano hoʻololi . ^ E Ha yM.

Mai ka pūnaehana hana ʻana: nā pākeke: pinepine - ka maʻi maʻamau, pinepine - kaila, ka luaʻi, nā keiki - pinepine - ka maʻi maʻamau, ka nausea, ka luaʻi, ka lehulehu holoʻokoʻa: nausea pinepine ka ʻike i ka wā e lawe ana i nā kiʻekiʻe kiʻekiʻe o ka lāʻau. Inā ma hope o ka hoʻomaka ʻana o ka lawe ʻana i ka lāʻau lapaʻau nā hopena kūlike mai ka hoʻowalewale ʻana, hiki ke hoʻopau ʻia inā ka lawe ʻana i ka lāʻau i ka hoʻomaka ʻana o ka ʻai. ʻO ka pinepine - ʻeha a me ka huehue, aneane loa - hoʻonaninani i ka antibiotika e pili ana i ka antibiotics (me ka pseudomembranous colitis a me ka hemorrhagic colitis), ke alualu lauoho lauoho, nā gastritis, stomatitis. I nā kamaliʻi, ke noi ʻana i ke kahuhina, discoloration o ka ʻili o ka papale o ka ʻili enamel niho i ʻike pinepine ʻia.

Ma ka ʻaoʻao o ka pūpū a me ka biliary tract: pinepine - i hoʻonui pinepine ʻia i ka hana o ACT a / a i ʻole ALT (ʻike ʻia i nā mea maʻi e loaʻa ana i ka therapy antibiotic beta-lactam, akā ʻike ke ʻano kuʻi o ka maʻi neʻe), aneane ʻole - hepatitis a me jaundice cholestatic (ua ʻike ʻia kēia mau hanana i ka wā o ka hana me nā poʻe ʻē aʻe penicillins a me cephalosporins), kahi piʻi i loko o ka neʻe ʻana o ka bilirubin a me ka phosphatase alkaline. ʻO nā hanana ʻino loa mai ka ate ka mea i nānā nui ʻia i nā kāne a me nā mea maʻi a hiki ke pili pū me ka lāʻau lōʻihi. ʻO nā hanana ʻino loa i nānā ʻole i nā keiki.

ʻO nā hōʻailona a me nā hōʻailona i hele pinepine ʻia ma ke a ma hope iho o ka pau ʻana o ka hoʻōla, eia naʻe i kekahi mau hihia ʻaʻole paha e ʻike ʻia no kekahi mau hebedoma ma hope o ka pau ʻana o ka maʻi. ʻO nā hanana ʻinoʻino ke hoʻololi pinepine ʻia. Hiki i nā pilikia hōʻeha mai ka luhi ka maʻi paʻakikī, ma nā hihia koʻikoʻi loa i hōʻike ʻia nā hopena o nā hopena hōʻeha. I ka hapa pinepine, ʻo kēia mau mea me ka pathology concomitant koʻikoʻi a i ʻole kekahi e loaʻa i nā lāʻau hepatotoxic i ka manawa like.

Mai nā ʻili a me ka ʻili o ka subcutaneous: pinepine - pinepine, kūmole, urectaria, līpeke - erythema multiforme, ʻokoʻa loa - Stevens-Johnson syndrome, necrolysis epidermalous, bullous exfoliative dermatitis, akahā pustulosis exanthematou.

Mai ka pūnaehana urinary: līpoki loa - neʻeneʻe interstitial nephritis, crystalluria, hematuria.

Nā Hoʻohui

  • hypersensitivity i ka amoxicillin, clavulanic acid, nā mea ʻē aʻe o ka lāʻau lapaʻau, beta-lactam antibiotics (e.g. penicillins, cephalosporins) i ke anamnesis,
  • nā hopena o mua o ka jaundice a i ʻole hemahema ka hana ʻana i ka wā e hoʻohana ai i ka hui pū ʻana o ka amoxicillin me ka clavulanic acid i ka mōʻaukala
  • ʻo nā keiki a hiki i ka 3 mau mahina (no kahi paila no ka hoʻomākaukau no ka hoʻomaʻamaʻa ʻana no ka hoʻopale ʻana i ka waha 200 mg / 28.5 mg ma 5 ml a me 400 mg / 57 mg ma 5 ml),
  • hana renal impaired (CC ma mua o 30 ml / min) - no ka pauku no ka hoʻopiʻi ʻana no ka hoʻokūkū waha 200 mg / 28.5 mg ma 5 ml a 400 mg / 57 mg ma 5 ml,
  • phenylketonuria.

Nā kaʻina hana: kaʻe ʻana o ka hana lūlū.

ʻŌpū a me ka lactation

I nā haʻawina o ka hana reproduction i nā holoholona, ​​waha a me ka hoʻoponopono makua ʻo Augmentin ® ʻaʻole i hopena i ka hopena teratogenic.

I loko o kahi haʻawina hoʻokahi i nā wahine me ka pupule mua o nā membranes, ua ʻike ʻia ka pili o ka prophylactic drug therapy e pili ana i ka nui o ka pilikia o ka necrotizing enterocolitis i ka poʻe hānau hou. E like me nā lāʻau āpau, ʻaʻole loea ʻia ʻo Augmentin ® no ka hoʻohana ʻana i ka wā hāpai, inā ʻaʻole ʻo ka pōmaikaʻi ka mea i manaʻo ʻia e ka ʻoihana ma mua o ka wahine.

Hiki ke hoʻohana ʻia ka lāʻau lapaʻau Augmentin ® i ka wā o ka umauma. Me ka ʻokoʻa ʻole o ka hoʻomohala ʻana i nā maʻi pakanā a i ʻole kandidiasis o nā membous waha o ka waha waha i hoʻopili ʻia me ka komo ʻana i loko o ka waiū o nā ʻāpana o nā mea ikaika o ka lāʻau lapaʻau, ʻaʻohe mau hopena ʻē aʻe i mālama ʻia i nā pēpē hānai. I ka hopena o nā hopena maikaʻiʻole i nā pēpē hānai hānai hānai, pono ke pani i ka hānai umauma.

Nā ʻōlelo kikoʻī

Ma mua o ka hoʻomaka ʻana i ka mālama ʻana me Augmentin ®, pono ia e hōʻiliʻili i ka moʻolelo olakino pili e pili ana i nā hopena hypersensitivity o mua i nā penicillins, cephalosporins a i nā mea waiwai ʻē aʻe e hōʻeha ai i kahi hopena maʻi i ka mea maʻi.

ʻO ka maʻi koʻikoʻi, a me kekahi manawa momona, nā hopena hypersensitivity (e pili ana i ka anaphylactic) i nā penicillins. Loaʻa ka hopena o kēlā mau hopena i ka poʻe maʻi me ka mōʻaukala o nā hopena hypersensitivity e pili ana i nā penicillins. Ma kahi o kahi hopena maʻi, pono ia e kāpae i ka mālamaʻana me Augmentin ® a hoʻomaka i kahi kūpono kūpono. Ma ka hihia o nā hopena hypersensitivity koʻikoʻi, e lawelawe koke ʻia ka epinephrine. Oxygen therapy, iv hoʻokō o GCS a me ka hāʻawi o ka airway patency, me nā intubation, pono pū kekahi.

Ma kahi o ka kānalua o ka mononucleosis infectious, ʻaʻole pono ʻo Augmentin ®, no ka mea i loko o nā mea maʻi me kēia maʻi, ʻo ka amoxicillin e hiki ke hōʻeha i ka ʻili o ka ʻili e like me ka ʻeha o ka maʻi, e hoʻopili ana i ka maʻi maʻi o ka maʻi.

Hoʻomaʻamaʻa ka lōʻihi o ka mālama ʻana me Augmentin ® i kekahi mau manawa i ka hoʻopuka nui ʻana o nā microorganisms insensitive.

Ma keʻano holoʻokoʻa, ʻae maikaʻi ʻia ʻo Augmentin ® a he mau haʻahaʻa haʻahaʻa haʻahaʻa no nā penicillins āpau.

I ka lōʻihi o ka hoʻokō ʻana me Augmentin ®, ka mea ia e loiloi pinepine i ka hana o nā kuhi, ʻāʻī a me nā ʻōnaehana hematopoiesis.

ʻO nā hihia o ka loaʻa ʻana o ka colitis pseudomembranous i ka wā e lawe ai i nā maʻi antibiotics i wehewehe, ʻo ka nui o kēlā me kēia ʻano e hoʻololi i ke ʻano hoʻoweliweli. No laila, he mea nui e noʻonoʻo i ka hiki ke hoʻomohala ʻana i ka colitis pseudomembranous i nā mea maʻi me ka maʻi maʻi i ka wā a ma hope o ka hoʻohana ʻana o nā antibiotics. Inā lōʻihi ke kaumaha a hōʻeha paha ka maʻi a hele paha ka mea maʻi i ka ʻōpū o ka ʻōpū, pono e hoʻokaʻawale ʻia ka mālama ʻana a pono e ʻike ʻia ka mea maʻi.

I ka poʻe maʻi e loaʻa ana i ka hui pū ʻana o ka amoxicillin me ka waila clavulanic i hui pū ʻia me ka anticoagulants indirect (waha), i nā hanana lohi, ua hōʻike ʻia ka piʻi ʻana o ka manawa prothrombin (hoʻonui i ka MHO). Me ka hoʻohui pūʻana o nā anticoagulants kūloko (waha) me ka hui pū ʻana o ka amoxicillin me ka clavulanic acid, pono ka nānā ʻana i nā kuhikuhi pono. No ka mālama ʻana i ka hopena i makemake ʻia o ka anticoagulants waha, pono paha ke hoʻoponopono ʻia.

I ka poʻe maʻi me ka hana renal impaired, pono ke hoʻemi ʻia ka nui o Augmentin ® e like me ia.

I nā maʻi me ka diuresis ho'ēmi, crystalluria pinepine loa i ka hanana, ʻo ka nui me ka lāʻau lapaʻau. Me ka hoʻomakaʻana o ka amoxicillin i nā kiʻekiʻena kiʻekiʻe, pono e hāpai i ka nui o ka waiʻoki a mālama i nā diuresis kūpono e hōʻemi ai i ka hopena o ka hoʻokumu ʻana o nā kristal amoxicillin.

Ke lawe nei ʻo Augmentin ® i loko, ke nānā nei ka nui o ka amoxicillin i loko o ka urine, hiki iā ia ke alakaʻi i nā hopena maikaʻi ʻole i ka hopena o ka glucose i ka pā (a me ka laʻana, kahi hōʻike Benedict, kahi hōʻike no Feling). I kēia hihia, ʻoi ʻia e hoʻohana i ke ʻano o ka glucose oxidant no ka hoʻoholo ʻana i ka ʻike ʻana o ka glucose i nā pāʻai.

Hiki i ka acid Clavulanic ke hoʻopuka i ka nonspecific o ka klase G immunoglobulin a me nā albumin i nā membran erythrocyte, kahi e alakaʻi ai i nā hopena maikaʻi ʻole o ka hoʻokolokolo Coombs.

E mālama ana ka mālama ʻōpiopio i ka pale ʻana i ka niho niho e pili ana i ka lawe ʻana i ka lāʻau, ʻoiai e lawa ka niho.

Ka hōʻino ʻana a me ka hilinaʻi kolohe

ʻAʻole i hilinaʻi ʻia ka lāʻau, hoʻohui a me ka hopena euphoria e pili ana me ka hoʻohana ʻana i ka lāʻau no Augmentin ®.

Hoʻokomo i ka hiki ke lawe i nā kaʻa a kāohi i nā mīkini

No ka mea e hōʻeha ka lāʻau lapaʻau i ka dizziness, pono e lapatai i nā mea maʻi e pili ana i ka pākōlani i ka wā e hoʻokele ai a hana paha me nā mīkini hoʻoneʻe.

Ke keu

Nā hōʻailona: nā gastrointestinal hōʻailona a me ke nānāʻole i ka wai-electrolyte. Ua wehewehe ʻia ka crystalluria Amoxicillin, i kekahi mau kūlana e alakaʻi i ka hiki ʻana o kahi hana hoʻokele. Hiki i nā hōʻemi ke hele mai i nā maʻi me ka hana ʻole a pau o ka pūpū, a me ka poʻe i loaʻa nā kaha kiʻekiʻe o ka lāʻau.

Hoʻomaʻamaʻa: nā maʻi gastrointestinal - hōʻailona hōʻola, e mālama pono ana i ka hoʻoponopono ʻana i ke kaulike wai-electrolyte. I kahi hihia o ka overdose, hiki i ke amoxicillin a me clavulanic acid ke hōʻea ʻia mai ke kahe koko e nā hemodialysis.

Hōʻike nā hopena o kahi hōʻike noiʻi i hana pū ʻia me 51 mau keiki ma kahi kikowaena ʻawaʻawa, ʻo ke alakaʻi o ka amoxicillin ma kahi haʻahaʻa o lalo iho o ka 250 mg / kg, ʻaʻole i alakaʻi i nā hōʻailona maʻi koʻikoʻi a ʻaʻole koi i ka lavage gastric.

Hoʻohui Kūʻai Kūʻai

Hoʻokuʻu ʻia ma ke kau inoa.

Ehia ka hopena o Suspona? ʻO ka kumukūʻai kumukūʻai i nā lāʻau lapaʻau ma:

  • ʻO Augmentin pauka no ka hoʻomākaukau no ka hoʻomaha ʻana o ka 125 / 31.25 - 118 - 161 mau rubles,
  • ʻO Augmentin pulupulu no ka hoʻomākaukau no ka hoʻomaha ʻana o 200 / 28.5 - 126 - 169 rubles,
  • ʻO Augmentin pauka no ka hoʻomākaukau ʻana o ke kāpena 400/57 - 240 - 291 mau rubles,
  • ʻO Augmentin EU pulupulu no ka hoʻomākaukau no ka hoʻomaha ʻana o 600 / 42.9 - 387 - 469 mau rubles,

Hoʻohui nūhou

ʻAʻole hoʻohana ʻia ka hoʻohana pinepine ʻana i ka lāʻau Augmentin ® a me ka probenecid. Hoʻololi ʻo Probenecid i ka pānaʻi tubular o ka amoxicillin, a no laila, i ka hoʻohana pinepine ʻana i ka lāʻau Augmentin ® a me ka probenecide hiki ke piʻi i ka ulu ʻana o ka hoʻomau i ke kahe koko o ka amoxicillin, akā ʻaʻole ka clavulanic acid.

ʻO ka hoʻohana like ʻana o ka allopurinol a me nā amoxicillin e hoʻonui i ka hopena o nā hopena alia o ka ʻili. I kēia manawa, ʻaʻohe ʻikepili i ka puke paʻi ma ka manawa like o ka hui ʻana o ka amoxicillin me ka clavulanic acid a me allopurinol.

Hiki i ka penicillins ke hoʻolohi i ka kinai o methotrexate mai ke kino ma o ka pale ʻana i ka ʻōlelo huna tubular, no laila, ka manawa like me ka hoʻohana ʻana i ka lāʻau Augmentin ® a me ka methotrexate hiki ke hoʻonui i ka lilo o ka huakaʻi o ka methotrexate.

E like me nā lāʻau lapaʻau hou, hiki i ka mākaukau o Augmentin ® ke hoʻopilikia i ka microflora o ka ʻōpū, e alakaʻi ana i ka hoʻoemi ʻana o ka hoʻoulu ʻana o ka estrogen mai ka ʻeha o ka gastrointestinal a me ka hoʻēmi ʻana o ka hana kūpono o nā ʻāpana hui i hui pū ʻia.

Hōʻike ka puke puke i nā hihia lihua o ka hoʻonui ʻana o ka MHO i nā mea maʻi me ka hoʻohana pū ʻana o acenocumarol a i ʻole warfarin a me amoxicillin. Inā pono e kuhikuhi kahakaha aku iā Augmentin ® me anticoagulants, pono ka nānā pono ʻana o ka manawa prothrombin a i ʻole MHO ke koho ʻana a kāpae paha iā Augmentin®, pono ʻia ka hoʻoponopono ʻana o nā anticoagulants no ka hoʻoponopono waha.

I ka poʻe maʻi e loaʻa ana i ka mycophenolate mofetil, ma hope o ka hoʻomaka ʻana o ka hoʻohana ʻana o ka hui o ʻoxxillillin me ka clavulanic acid, kahi hōʻemi i ka ʻike ʻana o ka metabolite ikaika, ka waika mycophenolic, ua nānā ʻia ma mua o ka lawe ʻana i ka hā aʻe o ka lāʻau i ka aneane 50%. ʻAʻole hiki i nā loli i loko o kēia neʻe ʻana i nā loli maʻamau i ka hoʻolaha ʻana o ka waila mycophenolic.

E hoʻokuʻu i ke ʻano a me ka ʻano

ʻO ka waihona lāʻau ka:

  1. ʻO Amoxicillin (i kapa ʻia e trihydrate),
  2. ʻO Clavulanic waikawa (i hōʻike ʻia ma ke ʻano o ka paʻakai pāhare).

Loaʻa i nā ʻano ʻano like ʻole:

  1. ʻĀpono. Ua manaʻo ia no ka hana ʻana o ke kāpoki ʻana o ka waha. Hoʻohana ʻia nā mea hoʻomaʻemaʻe kai e loaʻa: nā kūmole maloʻo (ʻulaʻula, "Light molases", raspberry), acid acidcinic, colloidal silicon dioxide, xanthan gum, hydroxypropyl methylcellulose, aspartame. Nā kikowaena i loko o nā pākuʻi. Hoʻokomo ʻia ka pahu bolo i kahi kāwele i hana ʻia i ka pahu.
  2. Nā Palaki I ka wā e hana ai iā lākou, ua hoʻohana ʻia nā mea like ʻole: silicon dioxide (anhydrous colloidal), sodium starch glycolate, titanium dioxide, cellulose (microcrystalline), dimethicone 500, magnesium stearate, macrogol, hypromellose (5, 15 cps). Hoʻopili ʻia ma 7, 10 mau papa i kahi pōpō. I loko o nā peke o kēlā mau pahu (i hana ʻia nā foil) kahi pālua.

ʻO ka Powder i manaʻo ʻia no ka hana ʻana o kahi pohō i loaʻa i ka UK (SmithKline Beecham Pharmaceuticals).

ʻO ka hopena Pharmacological

Kuhi ʻia ka hopena bacteriolytic. Hoʻomaʻamaʻa ka lāʻau i ka aerobic / anaerobic gram-maikaʻi, aerobic gram-negative microorganism. He kūpono loa i ka pale o ka hiki ke hana i ka beta-lactamase. Ma lalo o ka hopena o ka waikawa clavulanic, e hoʻonui ai ka pale ʻana i ka amoxicillin i ka mana o kahi mea like e like me ka beta-lactamase. I kēia hihia, aia kahi hoʻonui o ka hopena o kēia ʻano waiwai.

Hoʻomaʻaʻa ka lāʻau lapaʻau:

  • ʻO Legionella
  • ʻO Yersinia enterocolitica,
  • Streptococcus pneumoniae,
  • Paola
  • ʻO Bordetella pertussis,
  • Peptococcus spp.,
  • Bacillus anthracis,
  • Peptostreptococcus spp.,
  • Enterococcus faecium,
  • Streptococcus agalactiae,
  • Vibrio cholerae,
  • Listeria monocytogenes,
  • ʻO Borrelia ʻOihana
  • Moraxella catarrhalis,
  • Streptococcus
  • Proteus mirabilis,
  • Peptococcus spp.,
  • Leptospira icterohaemorrhagiae,
  • ʻO nā pyogenes Streptococcus,
  • Neisseria meningitidis,
  • Treponema pallidum,
  • ʻO ka helicobacter pylori,
  • Brucella spp.,
  • Streptococcus viridans,
  • ʻOla nani ʻoi,
  • Haemophilus influenza.

I ke koho ʻana i kahi lāʻau lapaʻau i kahi keiki, pono ke kauka i ke kumukūʻai pono o ka pohō nona.

Nā hōʻailona no ka hoʻohana ʻana

Ua kauoha ʻia ʻo Augmentin no nā maʻi maʻi bakteria e nā microorganism i pili i ka pehu o nā antibiotics.

  • nā hopena o nā iwi a me nā ʻalā: osteomyelitis,
  • nā maʻi odontogenic: periodontitis, sinusont odillogen sinusitis, pilikia ʻole o nā maʻi dental,
  • nāʻiʻa o ka ʻili, nā palupalu palupalu.
  • nā maʻi ʻeha hanu: bronchitis, lobar bronchopneumonia, empyema, maʻi hemo ʻole,
  • nā pūpū o ka ʻōnaehana genitourinary: cystitis, urethritis, pyelonephritis, seption abortion, syphilis, gonorrhea, nā maʻi o nā kino i ka wahi pelvic,
  • mai nā maʻi e hōʻea e like me ka hoʻopiʻi ʻana ma hope o ka hana: peritonitis.

Pēlā hoʻi, ʻo ka lāʻau lapaʻau e hoʻohana i ka hana maʻi, ke pale ʻana i nā hōʻeha hōʻeha hiki ke hele mai i ka wā o ka hana ma ka digestive tract, ʻāʻī, ke poʻo, ka pelvis, nā ʻōpū, nā mea pono, nā naʻau, nā ʻoihana dile.

Nā Hoʻohui

ʻO nā palapala āpau a Augmentin contraindicated no ka hoʻohana ʻana ma ke ʻano o nā hopena a i ʻole nā ​​maʻi i kahi kanaka:

  • He hopena ʻākina a i ʻole hypersensitivity i ka amoxicillin, clavulanic acid a i ʻole antibiotics mai ka hui o penicillins a cephalosporins,
  • ʻO ka hoʻomohala ʻana i ka hana jaundice a me ka nānā ʻole o ka hana maʻa i ka manawa ma mua me ka hoʻohana ʻana i nā lāʻau lapaʻau e loaʻa ana i ka amoxicillin a me ka clavulanic acid.

ʻO kekahi mauʻano dosage o Augmentin i ka ʻoihana i kuhikuhi ʻia i kēia mau hui hou aʻe.

1. Hoʻopaʻa 125 / 31.25:

2. Hoʻopilikia ʻana o 200 / 28.5 a me 400/57:

  • ʻO Phenylketonuria,
  • Hoʻololi ma kahi o cleince 30 mau / min,
  • Makahiki ma lalo o 3 mau mahina.

3. Nā papa o nā āpau (250/125, 500/125 a me 875/125):

  • ʻO ka makahiki ma lalo o 12 mau makahiki a i ʻole ka paona kino ma lalo o 40 kg,
  • Hoʻololi ka hoʻokumuʻana o ka creinine ma mua o 30 ml / min (wale nō no nā papa 875/125).

Nā ʻōkuhi no ka hoʻohana

ʻO nā keiki ma lalo o 12 mau makahiki a i ʻole ke kau ʻana o ke kino ma lalo o 40 kg e lawe iā Augmentin wale nō e hoʻokuʻu ʻia. I kēia hihia, hiki i nā pēpē ʻōpio ke emi aku ma nā mahina 3 mau mahina hiki ke hāʻawi wale ʻia i ka hoʻokuʻu pohō me ka nui o nā maʻi 125 / 31.25 mg. I nā keiki i ʻoi aku o nā makahiki he 3 mau makahiki, ʻae ʻia ka hoʻohana ʻana i nā pona me nā hala ʻana o nā mea ikaika. Ma muli o ke kumu no ka hoʻokuʻu ʻana o Augmentin i nā keiki, ua kapa pinepine ʻia ʻo ia he "keiki Augmentin" me ka ʻole o ka kikoʻī ana i ka ʻano hana (suspension). Hoʻololi ʻia nā helu o ke kakā no kēlā me kēia makahiki e pili ana i ka makahiki a me ke kaumaha o ke keiki.

Ke kuhikuhi nei nā ʻōkuhi no ka hoʻohana ʻana i ka nui o ka makemake o ka hoʻopiʻi ʻana i ka hopena (hoʻonā) ka ana e hoʻohana ana ma ke ana he ana me ke kīʻaha a i ʻole syringe. Ke lawe i ka lāʻau lapaʻau no nā keiki, hiki iā ʻoe ke hoʻohui i ke kōpana me ka wai, ma kahi hoʻohālike o kekahi i hoʻokahi, akā aia wale nō ma hope o ke ʻano loiloi koi ʻia.

  1. I mea e hōʻemi ai i nā pilikia a me nā hopena mai ka gastrointestinal tract, ʻoi ʻia ia e lawe i nā lāʻau lapaʻau a me ke pohō i ka hoʻomaka ʻana o kahi pāʻina. Eia naʻe, inā hiki ʻole kēia no kekahi kumu, a laila hiki ke lawe ʻia nā papa i kēlā me kēia manawa e pili ana i ka meaʻai, no ka mea ʻaʻole i hoʻopilikia nui ka ʻai i nā hopena o ka lāʻau.
  2. ʻO ka hana o nā papa pākuʻi a me nā mea hoʻowalewale, a me ka hoʻokele kūloko i ka hopena o Augmentin, e mālama ʻia i nā manawa maʻamau. ʻO kahi laʻana, inā pono ʻoe e lawe i ka lāʻau lapaʻau ʻelua i ka lā hoʻokahi, a laila pono ʻoe e mālama pono i ka manawa o 12 mau hola ma waena o nā pale. Inā pono e lawe Augmentin 3 mau manawa i ka lā, a laila pono ʻoe e hana i kēlā me kēia 8 mau hola, e ho'āʻo nei e nānā pono i kēia manawa, a me nā mea like.

I mea e helu ai i ka nui o ka lāʻau lapaʻau, pono ʻoe e hoʻohana i kēia mau pae aʻe:

Hoʻopaʻa 200 mg.

  • I hoʻokahi makahiki, ke kaupaona mai ka 2 a me 5 kg. - 1,5 - 2,5 ml 2 mau manawa i ka lā,
  • Mai ka makahiki 1 a i 5 mau makahiki, ke kaumaha mai 6 a 9 kg - 5 ml 2 mau manawa i ka lā.

Hoʻopaʻa 400 mg.

  • ʻO nā keiki mai ka makahiki a hiki i 5 mau makahiki, ke kaupaona mai 10 a 18 kg - 5 ml 2 mau manawa i ka lā,
  • Mai ka 6 a 9 mau makahiki, me ka paona o 19 i 28 kg -7.5 ml 2 mau manawa i ka lā,
  • ʻO nā keiki mai 10 a 12 paha makahiki, paona mai 29 a 39 kg - 10 ml ʻelua mau lā i ka lā.

Hoʻopaʻa 125 mg.

  • I hoʻokahi makahiki, ke kaupaona mai 2 a 5 kg - 1,5 - 2,5 ml 3 mau manawa i ka lā,
  • ʻO nā keiki mai hoʻokahi makahiki a 5 mau makahiki, paona mai 6 a 9 kg - 5 ml hoʻokahi lā i ka lā.
  • Mai hoʻokahi makahiki a me 5 mau makahiki, ke kaupaona mai 10 a 18 kg - 10 ml 3 mau manawa i ka lā,
  • Mai 6 a 9 mau makahiki, paona mai 19 a 28 kg - 15 ml 3 mau manawa i ka lā,
  • Mai 10 a 12 makahiki paha, paona mai 29 a 39 kg - 20 ml 3 mau manawa i ka lā.

Hoʻoholo ʻia ka nui o ka lāʻau lapaʻau ma muli o ke ʻano o ka maʻi maʻi, ka wā, ka papa, ke kaupaona a me ke ʻano o ka mea maʻi. Pono ka hoʻomanaʻo e hiki i ke kauka ke kākau wale i ka dosis i makemake ʻia i ka mea maʻi. I ka heluʻana o ka dosage, ʻoi aku ia e noʻonoʻo i ke kiko o ka sodium amoxicillin.

Na rula no ka hoomakaukau ana o ka hoopanee ana

Pono mākaukau i ka hoʻokuʻu ʻia ma mua o ka lawe ʻana i ka lāʻau. Hoʻomaka Kaʻai:

  1. E hoʻohui i 60 ml o ka wai kuke i ka mahana o ka lumi i ka pahu pauka, e pani i ka uhi a lūlū a hiki i ka pau ʻana o ka pauka. Next, pono ʻoe e ʻae i ka pahu pahu no 5 mau minuke, ʻae ʻia kēia no ka hoʻopau piha ʻana o ka lāʻau lapaʻau.
  2. E hoʻohui i ka wai i ka hōʻailona ma ka pahu lāʻau a lūlū hou i ka hue hou.
  3. E koi ka 125 mg / 31.25 mg i ka wai o 92 ml o ka wai, kahi momona o 200 mg / 28.5 mg a me 400 mg / 57 mg e koi i ka 64 ml wai.

Pono e lūlū ʻia ka ipu wai ma mua o kēlā me kēia hoʻohana. I mea e hōʻoia pono ai i ka hala o ka wai o ka lāʻau, pono ʻia e hoʻohana i ke kapa ʻona, i hoʻokomo ʻia i loko o ka ipu kuhi. Pono e hoʻomaʻemaʻe pono ka pale ana ma hope o kēlā me kēia hoʻohana.

ʻO kaʻoi aku o ke ola o ka hoʻoneʻe ʻana i hoʻopau ʻia ma mua o 1 mau pule i loko o ka friji. ʻAʻole pono ke kāʻei ʻia.

No nā mea maʻi i ʻoi aku ma mua o 2 mau makahiki, hiki i kahi kolo pākahi ke hoʻomākaukau ʻia i ka lāʻau me ka wai i hoʻolapalapa ʻia ai ka wai a 1: 1.

Nā hopena hopena

Manaʻo ʻia kahi maʻi e mālama ʻia no ke kino o nā keiki. Ua hoʻāʻo ʻia ka lāʻau lapaʻau i nā makahiki he nui, ma muli o kēia, ua ʻano noiʻi ʻia ka ʻano o kāna hana. No ka mea maoli, hiki i nā hopena ʻaoʻao, akā i ka liʻiliʻi o kā lākou hanana.

  • Mai ka pūnaehana ʻana, hiki paha i kēlā ʻano hopena maikaʻi ʻole: hoʻopuka, nausea, ʻeha ʻana. ʻOiai ke lawe nei i ka antibiotic, ʻo ka maʻiʻeha ka hōʻailona maʻamau maʻamau. Ke hoʻohana nei i ka hoʻōki, hiki ke loli ke ʻano o ka enamel ma nā niho o ke keiki, ʻaʻole kēia i kahi makaʻeha nui.
  • I kekahi mau hihia, loaʻa paha nā ʻano like like ʻole. I waena o lākou: ka pīhoihoi anaphylactic, dermatitis, vasculitis, maʻi ʻo Stevens-Johnson. I kekahi mau hihia, ulu kahi maʻi alaka, erythema, urticaria i ulu. Hiki i ke keiki ke hōʻeha nui i ke poʻo, ka ʻeha.

Hiki ke loaʻa kahi papa inoa piha o nā hopena pā o Augmentin no nā keiki i loko o nā kauoha no ka lāʻau lapaʻau. A ʻo nā ʻōlelo hoʻi no ka hoʻohana ʻana he papa inoa piha o nā ʻōmole a me nā ʻōhua no ke ʻano e hana ai i kahi papa o ka lāʻau lapaʻau.

I mea e pale ai i ke kino o ke keiki mai kēia mau mea koʻikoʻi, pono ia e nānā pono i ke ʻano o ka lāʻau lapaʻau i kauoha ʻia ai e kekahi loea.

Ke mālama nei a me ke ola o ka noho

Hōʻike ʻia e mālama i ka ʻupena i loaʻa ka lāʻau lapaʻau ma kahi kihi kahi i hiki ʻole ai i nā keiki. Pono e koho i kahi maloʻo, hiki ke kiʻekiʻe ka mea wela ma loko o 25 0 C. No nā lā 7-10 hiki iā ʻoe ke mālama i ka hoʻokuʻu a pau i ke ʻano o ke 2-8 degere. ʻO kahi pahola i manaʻo ʻia no ka hoʻonāukiuki i loko o kahi vein e pono koke e hoʻohana koke ma hope o ka hoʻomākaukau.

Waiho I Kou ManaʻO HoʻOpuka